Caenorhabditis elegans

30 known processes

ost-1 (CELE_C44B12.2)

Protein OST-1

ost-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
reproductive structure development GO:0048608 850 0.607
organ development GO:0048513 1102 0.514
Zebrafish Mouse
developmental process involved in reproduction GO:0003006 1165 0.497
post embryonic development GO:0009791 2152 0.440
cellular component assembly GO:0022607 293 0.417
organelle organization GO:0006996 783 0.413
gonad development GO:0008406 840 0.398
reproductive system development GO:0061458 850 0.357
multicellular organism reproduction GO:0032504 819 0.323
single organism organelle organization GO:1902589 501 0.311
cell development GO:0048468 696 0.260
single organism reproductive process GO:0044702 1196 0.237
sex differentiation GO:0007548 909 0.234
cell motility GO:0048870 313 0.214
Human
regulation of cellular metabolic process GO:0031323 305 0.207
regulation of macromolecule metabolic process GO:0060255 421 0.207
oviposition GO:0018991 364 0.188
development of primary sexual characteristics GO:0045137 840 0.185
sarcomere organization GO:0045214 10 0.182
body morphogenesis GO:0010171 620 0.182
multi organism reproductive behavior GO:0044705 387 0.180
behavior GO:0007610 527 0.179
anatomical structure formation involved in morphogenesis GO:0048646 250 0.169
Human Zebrafish
actin cytoskeleton organization GO:0030036 184 0.168
striated muscle cell development GO:0055002 157 0.163
positive regulation of metabolic process GO:0009893 187 0.163
locomotion GO:0040011 1634 0.161
Human
multicellular organismal reproductive process GO:0048609 815 0.159
regulation of multicellular organismal process GO:0051239 726 0.151
cellular component biogenesis GO:0044085 297 0.151
muscle cell differentiation GO:0042692 171 0.141
striated muscle cell differentiation GO:0051146 158 0.138
multi organism reproductive process GO:0044703 867 0.128
actin filament based process GO:0030029 191 0.127
genitalia development GO:0048806 741 0.126
rna metabolic process GO:0016070 228 0.125
embryo development GO:0009790 3052 0.124
tissue development GO:0009888 112 0.123
Zebrafish
gene expression GO:0010467 412 0.121
positive regulation of cellular process GO:0048522 332 0.120
Human
multi multicellular organism process GO:0044706 390 0.116
positive regulation of developmental process GO:0051094 408 0.115
cellular macromolecular complex assembly GO:0034622 184 0.109
cell substrate adhesion GO:0031589 1 0.109
regulation of gene expression GO:0010468 366 0.106
cytoskeleton organization GO:0007010 339 0.104
multi organism behavior GO:0051705 389 0.104
regulation of developmental process GO:0050793 684 0.103
catabolic process GO:0009056 318 0.099
embryo development ending in birth or egg hatching GO:0009792 2992 0.099
cell migration GO:0016477 306 0.096
Human
cellular biosynthetic process GO:0044249 315 0.092
macromolecule biosynthetic process GO:0009059 250 0.090
signal transduction GO:0007165 317 0.088
reproductive behavior GO:0019098 387 0.088
macromolecule localization GO:0033036 771 0.085
regulation of metabolic process GO:0019222 478 0.084
multicellular organismal reproductive behavior GO:0033057 384 0.081
cell surface receptor signaling pathway GO:0007166 149 0.081
cellular component assembly involved in morphogenesis GO:0010927 183 0.080
phosphorus metabolic process GO:0006793 232 0.078
single organism signaling GO:0044700 401 0.077
cellular component morphogenesis GO:0032989 318 0.077
Human
muscle contraction GO:0006936 43 0.076
myofibril assembly GO:0030239 154 0.076
regulation of phosphate metabolic process GO:0019220 81 0.075
regulation of biosynthetic process GO:0009889 189 0.074
regulation of primary metabolic process GO:0080090 292 0.074
multicellular organismal aging GO:0010259 812 0.073
gamete generation GO:0007276 461 0.072
actomyosin structure organization GO:0031032 154 0.071
protein complex subunit organization GO:0071822 280 0.070
organic substance biosynthetic process GO:1901576 323 0.068
myosin filament assembly GO:0031034 138 0.066
organic substance catabolic process GO:1901575 294 0.066
cell cycle GO:0007049 526 0.065
nervous system development GO:0007399 253 0.065
determination of adult lifespan GO:0008340 812 0.064
death GO:0016265 547 0.064
growth GO:0040007 562 0.062
signaling GO:0023052 401 0.062
muscle cell development GO:0055001 158 0.062
macromolecular complex assembly GO:0065003 193 0.061
positive regulation of multicellular organismal process GO:0051240 417 0.061
aging GO:0007568 812 0.061
organelle assembly GO:0070925 214 0.060
muscle structure development GO:0061061 191 0.059
lipid storage GO:0019915 565 0.058
protein modification process GO:0036211 207 0.058
cellular protein modification process GO:0006464 207 0.056
skeletal muscle organ development GO:0060538 3 0.056
embryonic morphogenesis GO:0048598 152 0.056
Zebrafish
regulation of multicellular organism growth GO:0040014 373 0.055
regulation of biological quality GO:0065008 741 0.054
negative regulation of metabolic process GO:0009892 240 0.054
endocytosis GO:0006897 819 0.054
receptor mediated endocytosis GO:0006898 715 0.054
embryonic body morphogenesis GO:0010172 49 0.054
nucleic acid metabolic process GO:0090304 299 0.053
generation of neurons GO:0048699 235 0.053
vesicle mediated transport GO:0016192 852 0.052
positive regulation of developmental growth GO:0048639 354 0.052
positive regulation of cellular metabolic process GO:0031325 178 0.052
negative regulation of biological process GO:0048519 567 0.051
Human
macromolecular complex subunit organization GO:0043933 320 0.051
single organism transport GO:0044765 447 0.051
regulation of nucleoside metabolic process GO:0009118 37 0.051
regulation of macromolecule biosynthetic process GO:0010556 189 0.050
hermaphrodite genitalia development GO:0040035 734 0.050
regulation of signal transduction GO:0009966 135 0.050
cellular protein complex assembly GO:0043623 178 0.049
cellular component movement GO:0006928 388 0.048
Human
maintenance of location GO:0051235 580 0.048
protein metabolic process GO:0019538 422 0.048
establishment of localization GO:0051234 1171 0.047
cellular response to organic substance GO:0071310 119 0.047
Mouse
localization of cell GO:0051674 313 0.047
Human
lipid localization GO:0010876 573 0.047
sexual reproduction GO:0019953 546 0.046
organic cyclic compound catabolic process GO:1901361 119 0.044
chemotaxis GO:0006935 120 0.044
protein localization GO:0008104 205 0.044
developmental growth GO:0048589 412 0.043
regulation of multicellular organismal development GO:2000026 317 0.043
Human
cell death GO:0008219 547 0.043
regulation of response to stimulus GO:0048583 243 0.043
response to organic substance GO:0010033 131 0.043
Mouse
protein complex biogenesis GO:0070271 186 0.042
organ morphogenesis GO:0009887 67 0.042
Zebrafish
actin filament organization GO:0007015 21 0.042
regulation of actin filament based process GO:0032970 22 0.041
inductive cell migration GO:0040039 145 0.041
positive regulation of response to stimulus GO:0048584 55 0.041
ovulation GO:0030728 33 0.040
cell proliferation GO:0008283 116 0.040
Human Mouse
macromolecule modification GO:0043412 218 0.040
cell fate commitment GO:0045165 139 0.039
striated muscle myosin thick filament assembly GO:0071688 138 0.039
transport GO:0006810 1093 0.038
cellular protein metabolic process GO:0044267 279 0.038
response to chemical GO:0042221 356 0.038
Mouse
intracellular signal transduction GO:0035556 96 0.038
macromolecule catabolic process GO:0009057 202 0.037
response to external stimulus GO:0009605 289 0.037
cell projection organization GO:0030030 231 0.037
regulation of locomotion GO:0040012 161 0.036
Human
transcription dna templated GO:0006351 168 0.036
biosynthetic process GO:0009058 323 0.036
cellular macromolecule biosynthetic process GO:0034645 247 0.036
muscle tissue development GO:0060537 1 0.035
meiotic cell cycle GO:0051321 335 0.034
organelle fission GO:0048285 363 0.034
cytokinesis GO:0000910 80 0.034
neurogenesis GO:0022008 236 0.033
regulation of catabolic process GO:0009894 57 0.032
regulation of phosphorus metabolic process GO:0051174 81 0.032
posttranscriptional regulation of gene expression GO:0010608 166 0.031
cell morphogenesis GO:0000902 163 0.031
Human
single organism carbohydrate metabolic process GO:0044723 29 0.031
single organism catabolic process GO:0044712 129 0.030
negative regulation of cellular process GO:0048523 239 0.030
Human
cellular localization GO:0051641 360 0.029
neuron recognition GO:0008038 83 0.029
regulation of cellular biosynthetic process GO:0031326 189 0.029
rna biosynthetic process GO:0032774 169 0.029
meiotic nuclear division GO:0007126 300 0.028
protein phosphorylation GO:0006468 85 0.028
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.028
lamellipodium assembly GO:0030032 2 0.028
phosphate containing compound metabolic process GO:0006796 232 0.027
positive regulation of growth GO:0045927 369 0.027
regulation of growth GO:0040008 409 0.027
multicellular organism growth GO:0035264 385 0.027
negative regulation of developmental process GO:0051093 227 0.027
Human
cellular response to chemical stimulus GO:0070887 129 0.026
Mouse
positive regulation of multicellular organism growth GO:0040018 352 0.026
biological adhesion GO:0022610 21 0.025
epithelium development GO:0060429 68 0.025
Zebrafish
regulation of cell communication GO:0010646 176 0.025
positive regulation of catalytic activity GO:0043085 59 0.025
myosin filament organization GO:0031033 138 0.025
tube development GO:0035295 126 0.025
Zebrafish
tissue morphogenesis GO:0048729 65 0.024
Zebrafish
neuron differentiation GO:0030182 217 0.024
regulation of cellular component organization GO:0051128 248 0.023
Human
positive regulation of protein metabolic process GO:0051247 45 0.023
regulation of organelle organization GO:0033043 164 0.023
female gamete generation GO:0007292 254 0.023
cell adhesion GO:0007155 21 0.023
nucleobase containing compound metabolic process GO:0006139 406 0.022
neuron development GO:0048666 199 0.022
positive regulation of cell communication GO:0010647 69 0.022
regulation of cell migration GO:0030334 55 0.022
Human
regulation of rna biosynthetic process GO:2001141 165 0.022
nucleotide catabolic process GO:0009166 77 0.021
regulation of developmental growth GO:0048638 389 0.021
negative regulation of macromolecule metabolic process GO:0010605 229 0.021
regulation of cell motility GO:2000145 57 0.021
Human
axonogenesis GO:0007409 102 0.021
nucleobase containing compound biosynthetic process GO:0034654 184 0.021
single organismal cell cell adhesion GO:0016337 10 0.021
system process GO:0003008 136 0.021
phosphorylation GO:0016310 116 0.020
positive regulation of macromolecule metabolic process GO:0010604 149 0.020
organophosphate catabolic process GO:0046434 81 0.020
regulation of cell proliferation GO:0042127 105 0.020
Human Mouse
post embryonic organ development GO:0048569 336 0.019
regulation of cellular protein metabolic process GO:0032268 75 0.019
cell cycle process GO:0022402 482 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
response to abiotic stimulus GO:0009628 152 0.019
germ cell development GO:0007281 351 0.019
small molecule metabolic process GO:0044281 186 0.018
negative regulation of vulval development GO:0040027 206 0.018
regulation of purine nucleotide catabolic process GO:0033121 35 0.018
regulation of transcription dna templated GO:0006355 164 0.018
single organism localization GO:1902578 518 0.018
carbohydrate derivative metabolic process GO:1901135 141 0.018
vulval development GO:0040025 333 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
epithelial tube morphogenesis GO:0060562 1 0.017
protein catabolic process GO:0030163 162 0.017
organic substance transport GO:0071702 113 0.017
axon development GO:0061564 163 0.017
negative regulation of nematode larval development GO:0061064 208 0.017
protein complex assembly GO:0006461 186 0.016
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.016
positive regulation of phosphate metabolic process GO:0045937 56 0.016
axonal fasciculation GO:0007413 79 0.016
organic acid metabolic process GO:0006082 47 0.016
cellular response to stress GO:0033554 162 0.015
programmed cell death GO:0012501 500 0.015
phagocytosis GO:0006909 115 0.015
regulation of hydrolase activity GO:0051336 45 0.015
er nucleus signaling pathway GO:0006984 66 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.015
apoptotic process GO:0006915 478 0.015
organophosphate metabolic process GO:0019637 125 0.015
carboxylic acid metabolic process GO:0019752 34 0.015
nucleoside catabolic process GO:0009164 78 0.015
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.015
aromatic compound catabolic process GO:0019439 116 0.015
regulation of phosphorylation GO:0042325 45 0.015
cellular amine metabolic process GO:0044106 15 0.014
regulation of apoptotic process GO:0042981 36 0.014
meiotic cell cycle process GO:1903046 170 0.014
regulation of anatomical structure size GO:0090066 46 0.014
cell morphogenesis involved in differentiation GO:0000904 112 0.014
regulation of nucleic acid templated transcription GO:1903506 165 0.014
digestive tract development GO:0048565 122 0.014
small gtpase mediated signal transduction GO:0007264 32 0.014
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
actin filament bundle assembly GO:0051017 3 0.013
cellular nitrogen compound biosynthetic process GO:0044271 192 0.013
regulation of catalytic activity GO:0050790 78 0.013
organonitrogen compound catabolic process GO:1901565 90 0.013
positive regulation of signal transduction GO:0009967 40 0.013
signal transduction by phosphorylation GO:0023014 31 0.013
regulation of cytoskeleton organization GO:0051493 41 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
regulation of intracellular signal transduction GO:1902531 77 0.013
homeostatic process GO:0042592 51 0.013
cell division GO:0051301 262 0.013
ribonucleotide catabolic process GO:0009261 75 0.013
oxoacid metabolic process GO:0043436 47 0.013
cellular catabolic process GO:0044248 199 0.013
regulation of nucleotide catabolic process GO:0030811 35 0.013
establishment of localization in cell GO:0051649 318 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
transcription from rna polymerase ii promoter GO:0006366 149 0.012
nucleic acid templated transcription GO:0097659 169 0.012
regulation of protein metabolic process GO:0051246 81 0.012
regulation of nitrogen compound metabolic process GO:0051171 222 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.012
regulation of molecular function GO:0065009 89 0.012
nucleoside phosphate metabolic process GO:0006753 108 0.012
heterocycle catabolic process GO:0046700 119 0.012
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.012
response to wounding GO:0009611 4 0.012
cell matrix adhesion GO:0007160 1 0.012
cellular protein localization GO:0034613 75 0.012
integrin mediated signaling pathway GO:0007229 1 0.012
ribonucleoside triphosphate catabolic process GO:0009203 72 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
carbohydrate derivative catabolic process GO:1901136 82 0.011
nucleotide metabolic process GO:0009117 108 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.011
negative regulation of post embryonic development GO:0048581 208 0.011
positive regulation of phosphorus metabolic process GO:0010562 56 0.011
regulation of signaling GO:0023051 172 0.011
response to acid chemical GO:0001101 4 0.011
negative regulation of cellular protein metabolic process GO:0032269 27 0.011
regulation of vulval development GO:0040028 248 0.011
cell recognition GO:0008037 85 0.011
regulation of gene silencing GO:0060968 3 0.011
negative regulation of response to dna damage stimulus GO:2001021 2 0.011
peptidyl lysine trimethylation GO:0018023 2 0.010
regulation of cell differentiation GO:0045595 81 0.010
negative regulation of response to stimulus GO:0048585 73 0.010
regulation of purine nucleotide metabolic process GO:1900542 37 0.010
regulation of cellular component movement GO:0051270 62 0.010
Human
cellular nitrogen compound catabolic process GO:0044270 119 0.010
positive regulation of protein transport GO:0051222 4 0.010

ost-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
myopathy DOID:423 0 0.022
muscular disease DOID:0080000 0 0.022
heart disease DOID:114 0 0.022
cardiomyopathy DOID:0050700 0 0.022
dilated cardiomyopathy DOID:12930 0 0.022
intrinsic cardiomyopathy DOID:0060036 0 0.022
cardiovascular system disease DOID:1287 0 0.022
musculoskeletal system disease DOID:17 0 0.022
muscle tissue disease DOID:66 0 0.022