Caenorhabditis elegans

26 known processes

his-18 (CELE_K06C4.10)

Protein HIS-18

his-18 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.153
embryo development ending in birth or egg hatching GO:0009792 2992 0.144
reproductive system development GO:0061458 850 0.111
single organism reproductive process GO:0044702 1196 0.110
locomotion GO:0040011 1634 0.102
post embryonic development GO:0009791 2152 0.101
genitalia development GO:0048806 741 0.098
sex differentiation GO:0007548 909 0.095
organ development GO:0048513 1102 0.093
reproductive structure development GO:0048608 850 0.093
transport GO:0006810 1093 0.093
Worm
development of primary sexual characteristics GO:0045137 840 0.090
developmental process involved in reproduction GO:0003006 1165 0.090
macromolecule localization GO:0033036 771 0.085
Worm
establishment of localization GO:0051234 1171 0.082
Worm
organelle organization GO:0006996 783 0.081
Yeast Worm
hermaphrodite genitalia development GO:0040035 734 0.078
multi organism reproductive process GO:0044703 867 0.076
Yeast
gonad development GO:0008406 840 0.076
regulation of biological quality GO:0065008 741 0.072
Worm
determination of adult lifespan GO:0008340 812 0.069
cell cycle process GO:0022402 482 0.068
Yeast
endocytosis GO:0006897 819 0.068
Worm
maintenance of location GO:0051235 580 0.067
Worm
lipid localization GO:0010876 573 0.066
Worm
lipid storage GO:0019915 565 0.065
Worm
meiotic cell cycle GO:0051321 335 0.065
Yeast
body morphogenesis GO:0010171 620 0.063
Worm
multicellular organismal aging GO:0010259 812 0.063
single organism localization GO:1902578 518 0.061
Worm
defense response GO:0006952 296 0.060
Worm
cell cycle GO:0007049 526 0.060
Yeast
vesicle mediated transport GO:0016192 852 0.060
Worm
multicellular organismal reproductive process GO:0048609 815 0.059
aging GO:0007568 812 0.059
cell development GO:0048468 696 0.055
Worm
single organism organelle organization GO:1902589 501 0.053
Yeast Worm
receptor mediated endocytosis GO:0006898 715 0.053
Worm
multicellular organism reproduction GO:0032504 819 0.052
sexual reproduction GO:0019953 546 0.052
Yeast
protein metabolic process GO:0019538 422 0.051
Yeast
regulation of macromolecule metabolic process GO:0060255 421 0.050
Yeast Worm
negative regulation of biological process GO:0048519 567 0.048
Yeast
regulation of multicellular organismal process GO:0051239 726 0.047
regulation of developmental process GO:0050793 684 0.045
cell death GO:0008219 547 0.045
cellular localization GO:0051641 360 0.044
Worm
single organism transport GO:0044765 447 0.043
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.043
establishment of localization in cell GO:0051649 318 0.042
Worm
cytoskeleton organization GO:0007010 339 0.041
Worm
growth GO:0040007 562 0.040
behavior GO:0007610 527 0.039
gene expression GO:0010467 412 0.039
Yeast Worm
regulation of growth GO:0040008 409 0.038
protein complex subunit organization GO:0071822 280 0.038
Worm
gamete generation GO:0007276 461 0.038
positive regulation of growth GO:0045927 369 0.038
developmental growth GO:0048589 412 0.038
programmed cell death GO:0012501 500 0.037
regulation of multicellular organism growth GO:0040014 373 0.037
macromolecular complex subunit organization GO:0043933 320 0.037
Yeast Worm
organelle fission GO:0048285 363 0.036
regulation of gene expression GO:0010468 366 0.036
Yeast Worm
nucleobase containing compound metabolic process GO:0006139 406 0.036
Yeast Worm
cellular protein modification process GO:0006464 207 0.036
Yeast
positive regulation of developmental process GO:0051094 408 0.036
regulation of developmental growth GO:0048638 389 0.036
positive regulation of multicellular organism growth GO:0040018 352 0.035
meiotic cell cycle process GO:1903046 170 0.035
Yeast
head development GO:0060322 1 0.035
cellular component movement GO:0006928 388 0.034
positive regulation of developmental growth GO:0048639 354 0.034
multi organism behavior GO:0051705 389 0.034
death GO:0016265 547 0.034
multicellular organism growth GO:0035264 385 0.034
regulation of metabolic process GO:0019222 478 0.034
Yeast Worm
meiotic nuclear division GO:0007126 300 0.034
post embryonic organ development GO:0048569 336 0.033
multicellular organismal reproductive behavior GO:0033057 384 0.032
apoptotic process GO:0006915 478 0.032
reproductive behavior GO:0019098 387 0.032
cellular protein metabolic process GO:0044267 279 0.032
Yeast
biosynthetic process GO:0009058 323 0.031
Yeast Worm
molting cycle GO:0042303 281 0.031
protein modification process GO:0036211 207 0.031
Yeast
actin cytoskeleton organization GO:0030036 184 0.031
Worm
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.031
macromolecule modification GO:0043412 218 0.031
Yeast
organic substance biosynthetic process GO:1901576 323 0.031
Yeast Worm
multi multicellular organism process GO:0044706 390 0.030
oviposition GO:0018991 364 0.030
positive regulation of cellular process GO:0048522 332 0.030
Worm
organelle assembly GO:0070925 214 0.030
Worm
regulation of primary metabolic process GO:0080090 292 0.030
Yeast Worm
single organism signaling GO:0044700 401 0.030
multi organism reproductive behavior GO:0044705 387 0.030
cellular biosynthetic process GO:0044249 315 0.030
Yeast Worm
negative regulation of gene expression GO:0010629 217 0.029
Yeast
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.029
Worm
vulval development GO:0040025 333 0.029
cellular component assembly GO:0022607 293 0.028
Worm
response to chemical GO:0042221 356 0.028
localization of cell GO:0051674 313 0.028
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.028
Yeast Worm
cell migration GO:0016477 306 0.028
protein complex assembly GO:0006461 186 0.028
Worm
nucleic acid metabolic process GO:0090304 299 0.027
Yeast Worm
cell motility GO:0048870 313 0.027
macromolecule biosynthetic process GO:0009059 250 0.027
Yeast Worm
protein complex biogenesis GO:0070271 186 0.027
Worm
gene silencing GO:0016458 143 0.026
Yeast
negative regulation of gene expression epigenetic GO:0045814 2 0.026
Yeast
germ cell development GO:0007281 351 0.026
muscle structure development GO:0061061 191 0.026
Worm
rna metabolic process GO:0016070 228 0.026
Yeast Worm
regulation of cellular metabolic process GO:0031323 305 0.026
Yeast Worm
striated muscle cell development GO:0055002 157 0.025
Worm
heterocycle biosynthetic process GO:0018130 187 0.025
Yeast Worm
anatomical structure formation involved in morphogenesis GO:0048646 250 0.025
Yeast Worm
regulation of multicellular organismal development GO:2000026 317 0.025
negative regulation of macromolecule metabolic process GO:0010605 229 0.025
Yeast
cellular component assembly involved in morphogenesis GO:0010927 183 0.025
Worm
organic cyclic compound biosynthetic process GO:1901362 195 0.025
Yeast Worm
regulation of cellular biosynthetic process GO:0031326 189 0.025
Yeast Worm
cell division GO:0051301 262 0.025
regulation of post embryonic development GO:0048580 260 0.025
positive regulation of metabolic process GO:0009893 187 0.024
Worm
muscle cell differentiation GO:0042692 171 0.024
Worm
macromolecular complex assembly GO:0065003 193 0.024
Worm
regulation of gene expression epigenetic GO:0040029 163 0.024
Yeast
actomyosin structure organization GO:0031032 154 0.024
Worm
signaling GO:0023052 401 0.024
signal transduction GO:0007165 317 0.023
negative regulation of metabolic process GO:0009892 240 0.023
Yeast
microtubule based process GO:0007017 182 0.023
striated muscle myosin thick filament assembly GO:0071688 138 0.023
Worm
myofibril assembly GO:0030239 154 0.023
Worm
myosin filament assembly GO:0031034 138 0.023
Worm
regulation of response to stimulus GO:0048583 243 0.023
cellular component biogenesis GO:0044085 297 0.023
Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.023
Yeast Worm
negative regulation of developmental process GO:0051093 227 0.023
cellular protein complex assembly GO:0043623 178 0.023
Worm
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.023
regulation of organelle organization GO:0033043 164 0.023
negative regulation of cellular process GO:0048523 239 0.023
Yeast
catabolic process GO:0009056 318 0.022
positive regulation of cellular metabolic process GO:0031325 178 0.022
Worm
regulation of biosynthetic process GO:0009889 189 0.022
Yeast Worm
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.022
Yeast Worm
secretion by cell GO:0032940 138 0.022
Worm
rna biosynthetic process GO:0032774 169 0.022
Yeast Worm
actin filament based process GO:0030029 191 0.021
Worm
response to wounding GO:0009611 4 0.021
positive regulation of macromolecule metabolic process GO:0010604 149 0.021
Worm
regulation of cellular component organization GO:0051128 248 0.021
nucleic acid templated transcription GO:0097659 169 0.021
Yeast Worm
muscle cell development GO:0055001 158 0.021
Worm
inductive cell migration GO:0040039 145 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.021
Worm
regulation of nematode larval development GO:0061062 260 0.021
cellular macromolecule biosynthetic process GO:0034645 247 0.021
Yeast Worm
cellular component morphogenesis GO:0032989 318 0.021
Worm
organic substance catabolic process GO:1901575 294 0.021
transcription from rna polymerase ii promoter GO:0006366 149 0.020
Yeast Worm
myosin filament organization GO:0031033 138 0.020
Worm
positive regulation of rna biosynthetic process GO:1902680 102 0.020
Worm
cellular macromolecular complex assembly GO:0034622 184 0.020
Worm
negative regulation of post embryonic development GO:0048581 208 0.020
chromosome segregation GO:0007059 180 0.020
small molecule metabolic process GO:0044281 186 0.020
nucleobase containing compound biosynthetic process GO:0034654 184 0.020
Yeast Worm
secretion GO:0046903 147 0.020
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.020
Yeast Worm
positive regulation of cellular biosynthetic process GO:0031328 109 0.019
Worm
negative regulation of nematode larval development GO:0061064 208 0.019
sensory organ morphogenesis GO:0090596 2 0.019
regulation of nucleic acid templated transcription GO:1903506 165 0.019
Yeast Worm
regulation of meiotic cell cycle GO:0051445 136 0.019
regulation of vulval development GO:0040028 248 0.019
regulation of cell cycle GO:0051726 194 0.019
neurogenesis GO:0022008 236 0.019
posttranscriptional regulation of gene expression GO:0010608 166 0.019
aromatic compound biosynthetic process GO:0019438 192 0.019
Yeast Worm
regulation of transcription dna templated GO:0006355 164 0.019
Yeast Worm
transcription dna templated GO:0006351 168 0.019
Yeast Worm
regulation of macromolecule biosynthetic process GO:0010556 189 0.019
Yeast Worm
macromolecule catabolic process GO:0009057 202 0.018
organonitrogen compound metabolic process GO:1901564 151 0.018
regulation of rna metabolic process GO:0051252 173 0.018
Yeast Worm
cellular nitrogen compound biosynthetic process GO:0044271 192 0.018
Yeast Worm
generation of neurons GO:0048699 235 0.018
chromosome organization GO:0051276 104 0.018
Yeast
regulation of cell cycle process GO:0010564 145 0.018
digestive system development GO:0055123 122 0.018
Worm
tube development GO:0035295 126 0.018
Worm
negative regulation of vulval development GO:0040027 206 0.018
digestive tract development GO:0048565 122 0.018
Worm
response to external stimulus GO:0009605 289 0.018
cell type specific apoptotic process GO:0097285 4 0.018
regulation of nuclear division GO:0051783 115 0.018
phosphorus metabolic process GO:0006793 232 0.017
posttranscriptional gene silencing by rna GO:0035194 143 0.017
oogenesis GO:0048477 229 0.017
cell projection organization GO:0030030 231 0.017
meiotic chromosome segregation GO:0045132 139 0.017
cell proliferation GO:0008283 116 0.017
cellular catabolic process GO:0044248 199 0.017
negative regulation of multicellular organismal process GO:0051241 236 0.016
gene silencing by rna GO:0031047 143 0.016
positive regulation of neurogenesis GO:0050769 4 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
regulation of meiosis GO:0040020 94 0.016
female gamete generation GO:0007292 254 0.016
embryonic morphogenesis GO:0048598 152 0.016
regulation of cell communication GO:0010646 176 0.016
posttranscriptional gene silencing GO:0016441 143 0.016
nervous system development GO:0007399 253 0.016
innate immune response GO:0045087 190 0.016
immune response GO:0006955 192 0.016
striated muscle cell differentiation GO:0051146 158 0.015
Worm
regulation of cell division GO:0051302 142 0.015
positive regulation of nucleic acid templated transcription GO:1903508 102 0.015
Worm
mitotic cell cycle process GO:1903047 194 0.015
protein catabolic process GO:0030163 162 0.015
chromatin assembly or disassembly GO:0006333 1 0.015
cellular response to stress GO:0033554 162 0.015
neuron projection development GO:0031175 187 0.015
rna interference GO:0016246 137 0.015
regulation of cytoplasmic transport GO:1903649 3 0.015
protein localization GO:0008104 205 0.014
neuron differentiation GO:0030182 217 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
negative regulation of cellular metabolic process GO:0031324 95 0.014
Yeast
neuron recognition GO:0008038 83 0.014
regulation of signaling GO:0023051 172 0.014
phagocytosis GO:0006909 115 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
axon development GO:0061564 163 0.014
phosphate containing compound metabolic process GO:0006796 232 0.014
regulation of cell proliferation GO:0042127 105 0.014
membrane organization GO:0061024 135 0.013
intracellular signal transduction GO:0035556 96 0.013
protein oligomerization GO:0051259 4 0.013
apoptotic cell clearance GO:0043277 111 0.013
axonal fasciculation GO:0007413 79 0.013
neuron development GO:0048666 199 0.013
positive regulation of transcription dna templated GO:0045893 102 0.013
Worm
positive regulation of biosynthetic process GO:0009891 109 0.013
Worm
organic substance transport GO:0071702 113 0.013
neuromuscular junction development GO:0007528 2 0.013
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
male anatomical structure morphogenesis GO:0090598 78 0.012
cell recognition GO:0008037 85 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.012
Worm
epithelial cell proliferation GO:0050673 1 0.012
cellular response to chemical stimulus GO:0070887 129 0.012
positive regulation of rna metabolic process GO:0051254 103 0.012
Worm
organic cyclic compound catabolic process GO:1901361 119 0.012
regulation of localization GO:0032879 194 0.012
engulfment of apoptotic cell GO:0043652 94 0.012
organic acid metabolic process GO:0006082 47 0.012
amine metabolic process GO:0009308 15 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
Yeast
cuticle development GO:0042335 100 0.012
carbohydrate derivative metabolic process GO:1901135 141 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.011
Yeast
chemotaxis GO:0006935 120 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
response to organic substance GO:0010033 131 0.011
regulation of rna biosynthetic process GO:2001141 165 0.011
Yeast Worm
phagocytosis engulfment GO:0006911 98 0.011
system process GO:0003008 136 0.011
oxoacid metabolic process GO:0043436 47 0.011
pharynx development GO:0060465 51 0.011
Worm
response to abiotic stimulus GO:0009628 152 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.011
Worm
carboxylic acid metabolic process GO:0019752 34 0.011
ribosome biogenesis GO:0042254 4 0.011
membrane invagination GO:0010324 98 0.011
cellular response to organic substance GO:0071310 119 0.011
cellular ketone metabolic process GO:0042180 14 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
feeding behavior GO:0007631 70 0.011
heterocycle catabolic process GO:0046700 119 0.011
regulation of behavior GO:0050795 97 0.011
glycosyl compound catabolic process GO:1901658 79 0.011
aromatic compound catabolic process GO:0019439 116 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
negative regulation of rna biosynthetic process GO:1902679 53 0.011
Yeast
regulation of signal transduction GO:0009966 135 0.010
regulation of intracellular signal transduction GO:1902531 77 0.010
cellular amine metabolic process GO:0044106 15 0.010
regulation of response to wounding GO:1903034 1 0.010
negative regulation of nucleic acid templated transcription GO:1903507 53 0.010
Yeast
cell projection morphogenesis GO:0048858 148 0.010
regulation of protein targeting GO:1903533 3 0.010
cellular response to abiotic stimulus GO:0071214 4 0.010
negative regulation of neurogenesis GO:0050768 4 0.010
response to acid chemical GO:0001101 4 0.010
spindle organization GO:0007051 92 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
nematode male tail tip morphogenesis GO:0045138 77 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.010
Yeast
nucleoside metabolic process GO:0009116 99 0.010
nucleobase containing small molecule metabolic process GO:0055086 115 0.010

his-18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.011