Caenorhabditis elegans

22 known processes

rol-3 (CELE_C16D9.2)

Protein ROL-3

rol-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 1634 0.579
establishment of localization GO:0051234 1171 0.399
Mouse Worm
post embryonic development GO:0009791 2152 0.366
Worm
behavior GO:0007610 527 0.321
gamete generation GO:0007276 461 0.285
Mouse Worm
embryo development GO:0009790 3052 0.275
multi organism reproductive process GO:0044703 867 0.270
Mouse Worm
growth GO:0040007 562 0.258
Human Worm
transport GO:0006810 1093 0.237
Mouse Worm
regulation of locomotion GO:0040012 161 0.233
regulation of developmental process GO:0050793 684 0.230
Worm Fly
multicellular organismal reproductive process GO:0048609 815 0.230
Mouse Worm
cellular component movement GO:0006928 388 0.214
body morphogenesis GO:0010171 620 0.208
single organism localization GO:1902578 518 0.203
Mouse Worm
single organism organelle organization GO:1902589 501 0.200
developmental process involved in reproduction GO:0003006 1165 0.200
regulation of biological quality GO:0065008 741 0.198
Worm
endocytosis GO:0006897 819 0.192
multicellular organism reproduction GO:0032504 819 0.188
Mouse Worm
positive regulation of multicellular organismal process GO:0051240 417 0.188
Worm Fly
sexual reproduction GO:0019953 546 0.183
Mouse Worm
sex differentiation GO:0007548 909 0.181
protein localization GO:0008104 205 0.179
Worm
cell development GO:0048468 696 0.174
Mouse Fly
germ cell development GO:0007281 351 0.174
multi organism reproductive behavior GO:0044705 387 0.168
female gamete generation GO:0007292 254 0.161
single organism signaling GO:0044700 401 0.148
Human Mouse Fly
single organism transport GO:0044765 447 0.146
Mouse Worm
developmental growth GO:0048589 412 0.137
Worm
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.137
cellular localization GO:0051641 360 0.137
Worm
protein metabolic process GO:0019538 422 0.130
phosphate containing compound metabolic process GO:0006796 232 0.129
Human Mouse Fly
cell migration GO:0016477 306 0.126
reproductive behavior GO:0019098 387 0.126
genitalia development GO:0048806 741 0.126
organelle fission GO:0048285 363 0.122
death GO:0016265 547 0.122
regulation of multicellular organismal process GO:0051239 726 0.119
Worm Fly
regulation of metabolic process GO:0019222 478 0.118
Mouse Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.116
regulation of multicellular organism growth GO:0040014 373 0.116
Worm
vesicle mediated transport GO:0016192 852 0.115
catabolic process GO:0009056 318 0.114
determination of adult lifespan GO:0008340 812 0.113
Worm
apoptotic process GO:0006915 478 0.111
multicellular organismal reproductive behavior GO:0033057 384 0.109
gene expression GO:0010467 412 0.107
Mouse
hermaphrodite genitalia development GO:0040035 734 0.105
single organism reproductive process GO:0044702 1196 0.104
Mouse Worm
reproductive structure development GO:0048608 850 0.104
cell motility GO:0048870 313 0.103
macromolecule localization GO:0033036 771 0.102
Worm
signaling GO:0023052 401 0.099
Human Mouse Fly
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.098
multicellular organismal aging GO:0010259 812 0.097
Worm
positive regulation of multicellular organism growth GO:0040018 352 0.096
Worm
development of primary sexual characteristics GO:0045137 840 0.095
anatomical structure formation involved in morphogenesis GO:0048646 250 0.092
regulation of developmental growth GO:0048638 389 0.092
Worm
multi organism behavior GO:0051705 389 0.092
localization of cell GO:0051674 313 0.091
lipid localization GO:0010876 573 0.090
Worm
oogenesis GO:0048477 229 0.090
programmed cell death GO:0012501 500 0.089
regulation of multicellular organismal development GO:2000026 317 0.089
Fly
oviposition GO:0018991 364 0.087
aging GO:0007568 812 0.087
Worm
cell cycle process GO:0022402 482 0.086
regulation of macromolecule metabolic process GO:0060255 421 0.086
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 192 0.084
cell cycle GO:0007049 526 0.084
maintenance of location GO:0051235 580 0.084
Worm
positive regulation of cellular metabolic process GO:0031325 178 0.081
reproductive system development GO:0061458 850 0.080
regulation of cellular metabolic process GO:0031323 305 0.079
Mouse Worm
establishment of localization in cell GO:0051649 318 0.078
Worm
positive regulation of developmental growth GO:0048639 354 0.078
Worm
nucleic acid templated transcription GO:0097659 169 0.077
multi multicellular organism process GO:0044706 390 0.075
organ development GO:0048513 1102 0.075
Fly
nucleobase containing compound metabolic process GO:0006139 406 0.072
lipid storage GO:0019915 565 0.072
Worm
heterocycle biosynthetic process GO:0018130 187 0.067
sensory organ morphogenesis GO:0090596 2 0.067
Fly
regulation of signal transduction GO:0009966 135 0.067
Human Mouse
molting cycle GO:0042303 281 0.067
organelle organization GO:0006996 783 0.066
Worm
cellular protein metabolic process GO:0044267 279 0.066
Human Mouse Fly
cellular response to organic substance GO:0071310 119 0.066
receptor mediated endocytosis GO:0006898 715 0.065
rna metabolic process GO:0016070 228 0.065
cellular protein modification process GO:0006464 207 0.064
Human Mouse Fly
cell death GO:0008219 547 0.062
regulation of localization GO:0032879 194 0.061
Mouse Worm
cell cell signaling GO:0007267 118 0.061
regulation of cell communication GO:0010646 176 0.061
Human Mouse Worm
negative regulation of biological process GO:0048519 567 0.060
Mouse Worm
gonad development GO:0008406 840 0.060
regulation of gene expression GO:0010468 366 0.059
Mouse
cation transmembrane transport GO:0098655 59 0.059
positive regulation of growth GO:0045927 369 0.059
Worm
regulation of cellular protein metabolic process GO:0032268 75 0.059
nucleic acid metabolic process GO:0090304 299 0.058
muscle organ development GO:0007517 26 0.057
regulation of growth GO:0040008 409 0.055
Worm
protein complex subunit organization GO:0071822 280 0.055
regulation of macromolecule biosynthetic process GO:0010556 189 0.055
feeding behavior GO:0007631 70 0.053
multicellular organism growth GO:0035264 385 0.053
Worm
regulation of rna biosynthetic process GO:2001141 165 0.053
positive regulation of developmental process GO:0051094 408 0.051
Worm Fly
regulation of anatomical structure size GO:0090066 46 0.050
macromolecular complex subunit organization GO:0043933 320 0.050
macromolecule biosynthetic process GO:0009059 250 0.050
organic substance biosynthetic process GO:1901576 323 0.048
signal transduction GO:0007165 317 0.047
Human Mouse Fly
cellular macromolecule localization GO:0070727 75 0.047
Worm
negative regulation of cellular process GO:0048523 239 0.046
Worm
regulation of nucleic acid templated transcription GO:1903506 165 0.044
regulation of organ morphogenesis GO:2000027 4 0.044
Fly
positive regulation of cellular process GO:0048522 332 0.044
Fly
rna biosynthetic process GO:0032774 169 0.043
response to chemical GO:0042221 356 0.043
Worm
regulation of transcription dna templated GO:0006355 164 0.043
secretion by cell GO:0032940 138 0.042
cytoskeleton organization GO:0007010 339 0.042
secretion GO:0046903 147 0.042
mitotic cell cycle process GO:1903047 194 0.041
response to external biotic stimulus GO:0043207 101 0.041
regulation of cellular component organization GO:0051128 248 0.041
Worm
regulation of biosynthetic process GO:0009889 189 0.041
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.040
cellular catabolic process GO:0044248 199 0.040
Worm
organic cyclic compound biosynthetic process GO:1901362 195 0.040
purine ribonucleoside catabolic process GO:0046130 75 0.040
regulation of signaling GO:0023051 172 0.040
Human Mouse
phosphorylation GO:0016310 116 0.039
Human Mouse Fly
regulation of response to stimulus GO:0048583 243 0.039
Human Mouse Worm
glycosyl compound metabolic process GO:1901657 100 0.038
negative regulation of metabolic process GO:0009892 240 0.038
Mouse
regulation of cellular biosynthetic process GO:0031326 189 0.037
cellular component biogenesis GO:0044085 297 0.036
Worm
chromosome organization GO:0051276 104 0.036
regulation of primary metabolic process GO:0080090 292 0.036
cellular response to chemical stimulus GO:0070887 129 0.036
ion transmembrane transport GO:0034220 91 0.036
regulation of cytoplasmic transport GO:1903649 3 0.035
Worm
purine containing compound metabolic process GO:0072521 95 0.035
positive regulation of metabolic process GO:0009893 187 0.035
cellular component morphogenesis GO:0032989 318 0.034
organic substance catabolic process GO:1901575 294 0.034
vulval development GO:0040025 333 0.034
macromolecule catabolic process GO:0009057 202 0.034
generation of neurons GO:0048699 235 0.034
Fly
synaptic transmission GO:0007268 106 0.034
regulation of cellular component size GO:0032535 40 0.033
phosphorus metabolic process GO:0006793 232 0.032
Human Mouse Fly
positive regulation of macromolecule metabolic process GO:0010604 149 0.032
phagocytosis GO:0006909 115 0.032
ribonucleotide metabolic process GO:0009259 99 0.032
meiotic cell cycle GO:0051321 335 0.032
protein phosphorylation GO:0006468 85 0.032
Human Mouse Fly
positive regulation of secretion GO:0051047 17 0.032
transmembrane transport GO:0055085 110 0.031
nuclear migration GO:0007097 54 0.031
transcription from rna polymerase ii promoter GO:0006366 149 0.031
cellular macromolecule biosynthetic process GO:0034645 247 0.031
small molecule metabolic process GO:0044281 186 0.031
negative regulation of macromolecule metabolic process GO:0010605 229 0.031
Mouse
phagocytosis engulfment GO:0006911 98 0.031
membrane organization GO:0061024 135 0.030
positive regulation of locomotion GO:0040017 42 0.030
protein modification process GO:0036211 207 0.030
Human Mouse Fly
purine nucleotide catabolic process GO:0006195 75 0.030
aromatic compound biosynthetic process GO:0019438 192 0.030
cation transport GO:0006812 78 0.029
nucleoside phosphate catabolic process GO:1901292 77 0.029
response to fibroblast growth factor GO:0071774 5 0.029
embryonic morphogenesis GO:0048598 152 0.028
microtubule based process GO:0007017 182 0.028
response to biotic stimulus GO:0009607 101 0.028
response to organic substance GO:0010033 131 0.028
ion transport GO:0006811 113 0.028
Mouse
neurogenesis GO:0022008 236 0.028
Fly
carbohydrate derivative metabolic process GO:1901135 141 0.027
response to external stimulus GO:0009605 289 0.026
Worm
apoptotic cell clearance GO:0043277 111 0.026
organelle localization GO:0051640 127 0.026
nucleoside phosphate metabolic process GO:0006753 108 0.026
single organism catabolic process GO:0044712 129 0.026
Worm
chromosome segregation GO:0007059 180 0.026
purine nucleoside metabolic process GO:0042278 92 0.026
single organism cellular localization GO:1902580 72 0.026
Worm
regulation of cell cycle GO:0051726 194 0.026
ribonucleotide catabolic process GO:0009261 75 0.025
posttranscriptional regulation of gene expression GO:0010608 166 0.025
purine nucleoside triphosphate catabolic process GO:0009146 72 0.025
organophosphate metabolic process GO:0019637 125 0.025
meiotic nuclear division GO:0007126 300 0.024
organonitrogen compound metabolic process GO:1901564 151 0.024
purine containing compound catabolic process GO:0072523 75 0.024
tissue development GO:0009888 112 0.024
Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.024
meiotic chromosome segregation GO:0045132 139 0.023
neurological system process GO:0050877 53 0.023
ribonucleoside metabolic process GO:0009119 98 0.023
skeletal muscle organ development GO:0060538 3 0.023
cellular component assembly involved in morphogenesis GO:0010927 183 0.023
developmental growth involved in morphogenesis GO:0060560 37 0.023
regulation of pharyngeal pumping GO:0043051 36 0.022
positive regulation of phosphate metabolic process GO:0045937 56 0.022
nucleobase containing small molecule metabolic process GO:0055086 115 0.022
system process GO:0003008 136 0.022
taxis GO:0042330 128 0.022
cell projection organization GO:0030030 231 0.022
negative regulation of gene expression GO:0010629 217 0.022
Mouse
regulation of rna metabolic process GO:0051252 173 0.022
cellular biosynthetic process GO:0044249 315 0.021
membrane invagination GO:0010324 98 0.021
memory GO:0007613 3 0.021
organelle assembly GO:0070925 214 0.021
Worm
nucleotide catabolic process GO:0009166 77 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.021
macromolecule modification GO:0043412 218 0.021
Human Mouse Fly
cellular macromolecular complex assembly GO:0034622 184 0.020
regulation of protein ubiquitination GO:0031396 3 0.020
nucleotide metabolic process GO:0009117 108 0.020
regulation of multi organism process GO:0043900 69 0.020
detection of external stimulus GO:0009581 4 0.020
positive regulation of transcription dna templated GO:0045893 102 0.020
nucleoside triphosphate metabolic process GO:0009141 87 0.020
neuron development GO:0048666 199 0.020
regulation of vulval development GO:0040028 248 0.020
regulation of behavior GO:0050795 97 0.020
regulation of neurotransmitter levels GO:0001505 36 0.020
response to wounding GO:0009611 4 0.020
defense response GO:0006952 296 0.019
pharyngeal pumping GO:0043050 58 0.019
neurotransmitter transport GO:0006836 32 0.019
positive regulation of cellular biosynthetic process GO:0031328 109 0.019
nucleoside triphosphate catabolic process GO:0009143 72 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.019
muscle structure development GO:0061061 191 0.019
cellular component assembly GO:0022607 293 0.018
Worm
response to other organism GO:0051707 101 0.018
cuticle development GO:0042335 100 0.018
ribonucleoside catabolic process GO:0042454 77 0.018
establishment of organelle localization GO:0051656 123 0.018
ribonucleoside triphosphate catabolic process GO:0009203 72 0.018
aromatic compound catabolic process GO:0019439 116 0.018
positive regulation of gene expression GO:0010628 112 0.018
regulation of protein metabolic process GO:0051246 81 0.018
glycosyl compound catabolic process GO:1901658 79 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.018
negative regulation of multicellular organismal process GO:0051241 236 0.018
eating behavior GO:0042755 59 0.018
post embryonic organ development GO:0048569 336 0.018
regulation of bmp signaling pathway GO:0030510 3 0.017
head development GO:0060322 1 0.017
regulation of nematode larval development GO:0061062 260 0.017
purine nucleotide metabolic process GO:0006163 95 0.017
transcription dna templated GO:0006351 168 0.017
regulation of phosphorus metabolic process GO:0051174 81 0.017
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 43 0.017
ribose phosphate metabolic process GO:0019693 99 0.017
nucleoside catabolic process GO:0009164 78 0.017
positive regulation of biosynthetic process GO:0009891 109 0.017
negative regulation of developmental process GO:0051093 227 0.017
biosynthetic process GO:0009058 323 0.016
regulation of cell differentiation GO:0045595 81 0.016
Fly
response to bacterium GO:0009617 86 0.016
purine ribonucleotide catabolic process GO:0009154 75 0.016
nucleobase containing compound catabolic process GO:0034655 114 0.016
calcium mediated signaling GO:0019722 3 0.016
organic cyclic compound catabolic process GO:1901361 119 0.016
neuron projection development GO:0031175 187 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.016
negative regulation of locomotion GO:0040013 21 0.016
single organism intracellular transport GO:1902582 70 0.015
Worm
striated muscle cell differentiation GO:0051146 158 0.015
actomyosin structure organization GO:0031032 154 0.015
intracellular signal transduction GO:0035556 96 0.015
Human Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.015
sensory perception of chemical stimulus GO:0007606 15 0.015
long term memory GO:0007616 2 0.015
defense response to gram negative bacterium GO:0050829 64 0.015
pigmentation GO:0043473 2 0.015
defense response to other organism GO:0098542 100 0.015
heterocycle catabolic process GO:0046700 119 0.015
cellular protein localization GO:0034613 75 0.015
Worm
regulation of reproductive process GO:2000241 66 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.014
nucleus localization GO:0051647 55 0.014
regulation of nitrogen compound metabolic process GO:0051171 222 0.014
engulfment of apoptotic cell GO:0043652 94 0.014
cell proliferation GO:0008283 116 0.014
Mouse
cellular response to inorganic substance GO:0071241 3 0.014
innate immune response GO:0045087 190 0.014
cellular protein complex assembly GO:0043623 178 0.014
purine ribonucleotide metabolic process GO:0009150 95 0.014
nucleoside metabolic process GO:0009116 99 0.014
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 2 0.014
cellular response to metal ion GO:0071248 3 0.014
neuron differentiation GO:0030182 217 0.014
Fly
positive regulation of neurogenesis GO:0050769 4 0.014
Fly
negative regulation of cellular metabolic process GO:0031324 95 0.014
negative regulation of post embryonic development GO:0048581 208 0.013
muscle cell differentiation GO:0042692 171 0.013
nematode male tail tip morphogenesis GO:0045138 77 0.013
epithelium development GO:0060429 68 0.013
Mouse Fly
sterol transport GO:0015918 4 0.013
negative regulation of rna metabolic process GO:0051253 53 0.013
adult behavior GO:0030534 3 0.013
rna localization GO:0006403 3 0.013
regulation of mitotic cell cycle GO:0007346 76 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.013
nervous system development GO:0007399 253 0.013
Fly
epithelial tube morphogenesis GO:0060562 1 0.013
regulation of synaptic transmission dopaminergic GO:0032225 1 0.013
response to nitrogen compound GO:1901698 25 0.012
regulation of striated muscle contraction GO:0006942 4 0.012
regulation of cellular localization GO:0060341 42 0.012
Worm
pronuclear migration GO:0035046 51 0.012
regulation of cell migration GO:0030334 55 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
striated muscle cell development GO:0055002 157 0.012
ras protein signal transduction GO:0007265 31 0.012
single fertilization GO:0007338 61 0.012
divalent metal ion transport GO:0070838 17 0.012
positive regulation of phosphorus metabolic process GO:0010562 56 0.012
nucleoside monophosphate metabolic process GO:0009123 46 0.012
regulation of cell cycle process GO:0010564 145 0.012
negative regulation of cellular biosynthetic process GO:0031327 65 0.012
regulation of cell motility GO:2000145 57 0.012
cell maturation GO:0048469 26 0.011
organic substance transport GO:0071702 113 0.011
Worm
negative regulation of biosynthetic process GO:0009890 65 0.011
meiotic cell cycle process GO:1903046 170 0.011
positive regulation of transport GO:0051050 32 0.011
muscle fiber development GO:0048747 2 0.011
cell division GO:0051301 262 0.011
purine ribonucleoside metabolic process GO:0046128 92 0.011
cellular response to stress GO:0033554 162 0.011
Worm
protein complex biogenesis GO:0070271 186 0.011
ribonucleoside monophosphate metabolic process GO:0009161 45 0.011
pharynx development GO:0060465 51 0.011
posttranscriptional gene silencing by rna GO:0035194 143 0.011
response to temperature stimulus GO:0009266 66 0.011
Worm
positive regulation of signaling GO:0023056 66 0.011
positive regulation of intracellular transport GO:0032388 2 0.011
developmental maturation GO:0021700 26 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
regulation of nucleocytoplasmic transport GO:0046822 3 0.011
Worm
negative regulation of cell communication GO:0010648 61 0.011
regulation of protein targeting GO:1903533 3 0.011
Worm
cell projection morphogenesis GO:0048858 148 0.011
sensory perception of taste GO:0050909 4 0.011
divalent inorganic cation transport GO:0072511 17 0.011
regulation of meiotic cell cycle GO:0051445 136 0.010
tube development GO:0035295 126 0.010
purine nucleoside monophosphate catabolic process GO:0009128 28 0.010
fertilization GO:0009566 63 0.010
establishment of nucleus localization GO:0040023 55 0.010
mechanosensory behavior GO:0007638 25 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.010
actin cytoskeleton organization GO:0030036 184 0.010
rna interference GO:0016246 137 0.010
cellular nitrogen compound catabolic process GO:0044270 119 0.010
response to topologically incorrect protein GO:0035966 82 0.010
single organism behavior GO:0044708 83 0.010
positive regulation of nucleic acid templated transcription GO:1903508 102 0.010
cytokinesis GO:0000910 80 0.010

rol-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.015
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011