Caenorhabditis elegans

0 known processes

hot-2 (CELE_Y39B6A.48)

Protein HOT-2

hot-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.503
embryo development ending in birth or egg hatching GO:0009792 2992 0.472
post embryonic development GO:0009791 2152 0.361
transport GO:0006810 1093 0.316
organ development GO:0048513 1102 0.277
establishment of localization GO:0051234 1171 0.240
single organism signaling GO:0044700 401 0.188
locomotion GO:0040011 1634 0.177
endocytosis GO:0006897 819 0.176
vesicle mediated transport GO:0016192 852 0.164
developmental process involved in reproduction GO:0003006 1165 0.155
single organism organelle organization GO:1902589 501 0.148
organelle organization GO:0006996 783 0.147
regulation of metabolic process GO:0019222 478 0.142
regulation of multicellular organismal process GO:0051239 726 0.140
single organism reproductive process GO:0044702 1196 0.137
macromolecule localization GO:0033036 771 0.123
cytoskeleton organization GO:0007010 339 0.122
multicellular organismal aging GO:0010259 812 0.119
phosphorus metabolic process GO:0006793 232 0.118
receptor mediated endocytosis GO:0006898 715 0.115
multi organism reproductive process GO:0044703 867 0.114
determination of adult lifespan GO:0008340 812 0.110
multicellular organismal reproductive process GO:0048609 815 0.109
sexual reproduction GO:0019953 546 0.109
regulation of developmental process GO:0050793 684 0.107
cell surface receptor signaling pathway GO:0007166 149 0.106
negative regulation of biological process GO:0048519 567 0.098
cell development GO:0048468 696 0.097
single organism localization GO:1902578 518 0.097
response to chemical GO:0042221 356 0.096
signal transduction GO:0007165 317 0.095
regulation of localization GO:0032879 194 0.094
developmental growth GO:0048589 412 0.093
signaling GO:0023052 401 0.093
sex differentiation GO:0007548 909 0.093
behavior GO:0007610 527 0.092
regulation of cellular component organization GO:0051128 248 0.091
regulation of biological quality GO:0065008 741 0.090
regulation of signaling GO:0023051 172 0.089
development of primary sexual characteristics GO:0045137 840 0.089
establishment of localization in cell GO:0051649 318 0.088
growth GO:0040007 562 0.087
genitalia development GO:0048806 741 0.085
aging GO:0007568 812 0.085
tissue development GO:0009888 112 0.084
regulation of growth GO:0040008 409 0.081
cell motility GO:0048870 313 0.081
protein complex subunit organization GO:0071822 280 0.080
single organism transport GO:0044765 447 0.078
apoptotic process GO:0006915 478 0.077
death GO:0016265 547 0.077
lipid storage GO:0019915 565 0.074
oviposition GO:0018991 364 0.073
germ cell development GO:0007281 351 0.073
cellular localization GO:0051641 360 0.072
cellular protein modification process GO:0006464 207 0.071
phosphate containing compound metabolic process GO:0006796 232 0.071
organic substance catabolic process GO:1901575 294 0.070
macromolecular complex subunit organization GO:0043933 320 0.070
lipid localization GO:0010876 573 0.070
regulation of multicellular organismal development GO:2000026 317 0.068
multicellular organism reproduction GO:0032504 819 0.067
protein metabolic process GO:0019538 422 0.066
response to external stimulus GO:0009605 289 0.066
muscle cell development GO:0055001 158 0.066
maintenance of location GO:0051235 580 0.065
multicellular organism growth GO:0035264 385 0.065
cellular component movement GO:0006928 388 0.064
regulation of gene expression GO:0010468 366 0.063
gamete generation GO:0007276 461 0.063
regulation of multicellular organism growth GO:0040014 373 0.063
neurogenesis GO:0022008 236 0.062
regulation of nitrogen compound metabolic process GO:0051171 222 0.062
hermaphrodite genitalia development GO:0040035 734 0.061
multicellular organismal reproductive behavior GO:0033057 384 0.060
response to abiotic stimulus GO:0009628 152 0.060
localization of cell GO:0051674 313 0.058
cellular component morphogenesis GO:0032989 318 0.058
programmed cell death GO:0012501 500 0.058
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.058
regulation of primary metabolic process GO:0080090 292 0.057
memory GO:0007613 3 0.057
muscle structure development GO:0061061 191 0.056
muscle tissue development GO:0060537 1 0.056
immune response GO:0006955 192 0.056
cell migration GO:0016477 306 0.055
regulation of developmental growth GO:0048638 389 0.055
synaptic transmission GO:0007268 106 0.053
positive regulation of developmental process GO:0051094 408 0.053
regulation of cell communication GO:0010646 176 0.053
macromolecule modification GO:0043412 218 0.053
cell death GO:0008219 547 0.053
reproductive system development GO:0061458 850 0.052
multi organism behavior GO:0051705 389 0.051
nucleic acid metabolic process GO:0090304 299 0.050
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.050
positive regulation of multicellular organismal process GO:0051240 417 0.050
cell cell signaling GO:0007267 118 0.049
female gamete generation GO:0007292 254 0.049
muscle cell differentiation GO:0042692 171 0.049
secretion GO:0046903 147 0.049
enzyme linked receptor protein signaling pathway GO:0007167 50 0.048
body morphogenesis GO:0010171 620 0.048
cellular catabolic process GO:0044248 199 0.048
ribose phosphate metabolic process GO:0019693 99 0.048
actin cytoskeleton organization GO:0030036 184 0.048
protein modification process GO:0036211 207 0.047
anatomical structure formation involved in morphogenesis GO:0048646 250 0.047
cellular component biogenesis GO:0044085 297 0.047
membrane organization GO:0061024 135 0.047
skeletal muscle organ development GO:0060538 3 0.047
positive regulation of growth GO:0045927 369 0.046
nucleobase containing compound biosynthetic process GO:0034654 184 0.045
biosynthetic process GO:0009058 323 0.045
positive regulation of developmental growth GO:0048639 354 0.045
macromolecular complex assembly GO:0065003 193 0.045
catabolic process GO:0009056 318 0.045
gonad development GO:0008406 840 0.045
carbohydrate derivative metabolic process GO:1901135 141 0.045
cell cycle process GO:0022402 482 0.045
head development GO:0060322 1 0.045
cell cycle GO:0007049 526 0.044
neuron development GO:0048666 199 0.043
reproductive structure development GO:0048608 850 0.043
positive regulation of multicellular organism growth GO:0040018 352 0.041
cellular biosynthetic process GO:0044249 315 0.041
organic substance biosynthetic process GO:1901576 323 0.041
regulation of signal transduction GO:0009966 135 0.041
multi organism reproductive behavior GO:0044705 387 0.040
protein localization GO:0008104 205 0.040
embryonic morphogenesis GO:0048598 152 0.040
oogenesis GO:0048477 229 0.040
acetate ester metabolic process GO:1900619 4 0.039
response to temperature stimulus GO:0009266 66 0.039
nucleobase containing compound metabolic process GO:0006139 406 0.039
organophosphate metabolic process GO:0019637 125 0.039
macromolecule catabolic process GO:0009057 202 0.039
organonitrogen compound metabolic process GO:1901564 151 0.038
aromatic compound biosynthetic process GO:0019438 192 0.038
organ morphogenesis GO:0009887 67 0.038
regulation of cellular metabolic process GO:0031323 305 0.037
secretion by cell GO:0032940 138 0.037
gene expression GO:0010467 412 0.037
actin filament based process GO:0030029 191 0.037
ribonucleotide metabolic process GO:0009259 99 0.035
reproductive behavior GO:0019098 387 0.035
acetylcholine catabolic process GO:0006581 4 0.035
protein complex biogenesis GO:0070271 186 0.035
purine nucleotide metabolic process GO:0006163 95 0.034
regulation of phosphate metabolic process GO:0019220 81 0.034
single organism cellular localization GO:1902580 72 0.034
regulation of response to stimulus GO:0048583 243 0.034
protein phosphorylation GO:0006468 85 0.033
mitotic spindle organization GO:0007052 81 0.033
phosphorylation GO:0016310 116 0.033
regulation of macromolecule metabolic process GO:0060255 421 0.033
organic cyclic compound biosynthetic process GO:1901362 195 0.033
acetylcholine metabolic process GO:0008291 4 0.032
positive regulation of cellular process GO:0048522 332 0.032
striated muscle cell differentiation GO:0051146 158 0.032
cellular protein complex assembly GO:0043623 178 0.032
heterocycle biosynthetic process GO:0018130 187 0.031
protein catabolic process GO:0030163 162 0.031
regulation of locomotion GO:0040012 161 0.031
single organism behavior GO:0044708 83 0.031
purine containing compound metabolic process GO:0072521 95 0.031
regulation of behavior GO:0050795 97 0.031
cellular component assembly involved in morphogenesis GO:0010927 183 0.031
cellular protein metabolic process GO:0044267 279 0.031
regulation of phosphorus metabolic process GO:0051174 81 0.031
small molecule metabolic process GO:0044281 186 0.030
nervous system development GO:0007399 253 0.030
organelle fission GO:0048285 363 0.030
cellular macromolecular complex assembly GO:0034622 184 0.030
cellular component assembly GO:0022607 293 0.030
regulation of synaptic transmission GO:0050804 34 0.030
adult behavior GO:0030534 3 0.030
transcription from rna polymerase ii promoter GO:0006366 149 0.030
regulation of reproductive process GO:2000241 66 0.030
defense response GO:0006952 296 0.030
generation of neurons GO:0048699 235 0.030
negative regulation of gene expression GO:0010629 217 0.030
negative regulation of metabolic process GO:0009892 240 0.030
protein complex assembly GO:0006461 186 0.029
apoptotic cell clearance GO:0043277 111 0.029
rna metabolic process GO:0016070 228 0.029
regulation of organelle organization GO:0033043 164 0.029
intracellular signal transduction GO:0035556 96 0.029
regulation of cell differentiation GO:0045595 81 0.029
establishment of organelle localization GO:0051656 123 0.029
cell division GO:0051301 262 0.029
response to mechanical stimulus GO:0009612 28 0.029
organic substance transport GO:0071702 113 0.028
neuron differentiation GO:0030182 217 0.028
myofibril assembly GO:0030239 154 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.028
system process GO:0003008 136 0.028
positive regulation of cellular metabolic process GO:0031325 178 0.027
epithelium development GO:0060429 68 0.027
striated muscle cell development GO:0055002 157 0.027
positive regulation of metabolic process GO:0009893 187 0.027
regulation of neuromuscular synaptic transmission GO:1900073 1 0.027
response to biotic stimulus GO:0009607 101 0.027
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.027
regulation of macromolecule biosynthetic process GO:0010556 189 0.026
organelle assembly GO:0070925 214 0.026
regulation of multi organism process GO:0043900 69 0.026
carbohydrate derivative catabolic process GO:1901136 82 0.026
ion transmembrane transport GO:0034220 91 0.025
cell projection organization GO:0030030 231 0.025
ion transport GO:0006811 113 0.025
actomyosin structure organization GO:0031032 154 0.025
nucleoside triphosphate catabolic process GO:0009143 72 0.025
regulation of rna biosynthetic process GO:2001141 165 0.025
single organism catabolic process GO:0044712 129 0.025
multi multicellular organism process GO:0044706 390 0.025
innate immune response GO:0045087 190 0.024
nucleotide metabolic process GO:0009117 108 0.024
positive regulation of phosphorus metabolic process GO:0010562 56 0.024
myosin filament assembly GO:0031034 138 0.024
meiotic nuclear division GO:0007126 300 0.024
cellular nitrogen compound catabolic process GO:0044270 119 0.024
negative regulation of macromolecule metabolic process GO:0010605 229 0.024
regulation of cell cycle GO:0051726 194 0.024
nucleoside metabolic process GO:0009116 99 0.024
muscle system process GO:0003012 43 0.023
nucleobase containing small molecule metabolic process GO:0055086 115 0.023
cell type specific apoptotic process GO:0097285 4 0.023
regulation of cell cycle process GO:0010564 145 0.023
nucleobase containing compound catabolic process GO:0034655 114 0.023
transmembrane transport GO:0055085 110 0.023
ribonucleoside triphosphate metabolic process GO:0009199 87 0.023
positive regulation of cell migration GO:0030335 3 0.023
ribonucleoside catabolic process GO:0042454 77 0.023
regulation of synapse assembly GO:0051963 2 0.023
nucleoside phosphate catabolic process GO:1901292 77 0.023
axon development GO:0061564 163 0.023
regulation of ion transport GO:0043269 39 0.022
meiotic cell cycle GO:0051321 335 0.022
neuron projection development GO:0031175 187 0.022
regulation of catalytic activity GO:0050790 78 0.022
mitotic cell cycle process GO:1903047 194 0.022
response to organic substance GO:0010033 131 0.022
negative regulation of signaling GO:0023057 61 0.022
macromolecule biosynthetic process GO:0009059 250 0.022
g protein coupled receptor signaling pathway GO:0007186 46 0.022
response to wounding GO:0009611 4 0.022
regulation of cellular biosynthetic process GO:0031326 189 0.022
phagocytosis engulfment GO:0006911 98 0.022
nucleoside phosphate metabolic process GO:0006753 108 0.022
organelle localization GO:0051640 127 0.022
negative regulation of developmental process GO:0051093 227 0.021
regeneration GO:0031099 4 0.021
cellular response to abiotic stimulus GO:0071214 4 0.021
response to external biotic stimulus GO:0043207 101 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.021
response to other organism GO:0051707 101 0.021
spindle localization GO:0051653 51 0.021
purine ribonucleotide metabolic process GO:0009150 95 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.021
phagocytosis GO:0006909 115 0.020
negative regulation of response to stimulus GO:0048585 73 0.020
feeding behavior GO:0007631 70 0.020
purine nucleoside catabolic process GO:0006152 75 0.020
response to heat GO:0009408 50 0.020
striated muscle myosin thick filament assembly GO:0071688 138 0.020
positive regulation of phosphate metabolic process GO:0045937 56 0.020
response to osmotic stress GO:0006970 29 0.020
chemotaxis GO:0006935 120 0.020
muscle contraction GO:0006936 43 0.020
negative regulation of locomotion GO:0040013 21 0.020
regulation of cellular localization GO:0060341 42 0.020
inductive cell migration GO:0040039 145 0.020
regulation of transport GO:0051049 91 0.019
ribonucleotide catabolic process GO:0009261 75 0.019
purine ribonucleotide catabolic process GO:0009154 75 0.019
digestive system development GO:0055123 122 0.019
purine nucleoside metabolic process GO:0042278 92 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.019
cation transmembrane transport GO:0098655 59 0.019
purine ribonucleoside catabolic process GO:0046130 75 0.019
small gtpase mediated signal transduction GO:0007264 32 0.019
negative regulation of cell communication GO:0010648 61 0.019
regulation of feeding behavior GO:0060259 38 0.019
heterocycle catabolic process GO:0046700 119 0.018
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.018
pharyngeal pumping GO:0043050 58 0.018
cell morphogenesis GO:0000902 163 0.018
aromatic compound catabolic process GO:0019439 116 0.018
sensory organ morphogenesis GO:0090596 2 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
cellular macromolecule biosynthetic process GO:0034645 247 0.018
oocyte differentiation GO:0009994 45 0.018
regulation of rna metabolic process GO:0051252 173 0.018
regulation of protein localization GO:0032880 50 0.018
neuron projection morphogenesis GO:0048812 114 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.018
nucleic acid templated transcription GO:0097659 169 0.018
cellular response to stress GO:0033554 162 0.018
eating behavior GO:0042755 59 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.018
oocyte development GO:0048599 44 0.018
molting cycle GO:0042303 281 0.017
vulval development GO:0040025 333 0.017
posttranscriptional gene silencing GO:0016441 143 0.017
establishment of protein localization to membrane GO:0090150 3 0.017
organonitrogen compound catabolic process GO:1901565 90 0.017
negative regulation of signal transduction GO:0009968 60 0.017
membrane invagination GO:0010324 98 0.017
cellular nitrogen compound biosynthetic process GO:0044271 192 0.017
ribonucleoside metabolic process GO:0009119 98 0.017
myosin filament organization GO:0031033 138 0.017
nucleoside triphosphate metabolic process GO:0009141 87 0.017
post embryonic organ development GO:0048569 336 0.017
tube development GO:0035295 126 0.017
regulation of neurotransmitter levels GO:0001505 36 0.017
gene silencing by rna GO:0031047 143 0.017
cellular response to chemical stimulus GO:0070887 129 0.017
nucleotide catabolic process GO:0009166 77 0.017
negative regulation of cellular process GO:0048523 239 0.017
regulation of catabolic process GO:0009894 57 0.016
engulfment of apoptotic cell GO:0043652 94 0.016
regulation of molecular function GO:0065009 89 0.016
amine metabolic process GO:0009308 15 0.016
epithelial tube morphogenesis GO:0060562 1 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
canonical wnt signaling pathway GO:0060070 3 0.016
neuron projection guidance GO:0097485 82 0.016
transcription dna templated GO:0006351 168 0.016
nucleoside catabolic process GO:0009164 78 0.016
cell projection morphogenesis GO:0048858 148 0.016
rna interference GO:0016246 137 0.016
regulation of post embryonic development GO:0048580 260 0.016
regulation of intracellular signal transduction GO:1902531 77 0.016
regulation of transcription dna templated GO:0006355 164 0.016
cation transport GO:0006812 78 0.016
regulation of protein metabolic process GO:0051246 81 0.016
nematode male tail tip morphogenesis GO:0045138 77 0.016
organic cyclic compound catabolic process GO:1901361 119 0.016
positive regulation of transcription dna templated GO:0045893 102 0.016
purine ribonucleoside metabolic process GO:0046128 92 0.016
embryonic body morphogenesis GO:0010172 49 0.015
spindle organization GO:0007051 92 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
cellular amine metabolic process GO:0044106 15 0.015
axon guidance GO:0007411 82 0.015
purine containing compound catabolic process GO:0072523 75 0.015
taxis GO:0042330 128 0.015
regulation of nucleoside metabolic process GO:0009118 37 0.015
organic acid metabolic process GO:0006082 47 0.015
cell proliferation GO:0008283 116 0.015
muscle organ morphogenesis GO:0048644 4 0.015
purine nucleoside triphosphate metabolic process GO:0009144 87 0.015
developmental maturation GO:0021700 26 0.015
gene silencing GO:0016458 143 0.015
lipid metabolic process GO:0006629 77 0.015
cell fate commitment GO:0045165 139 0.015
cellular macromolecule localization GO:0070727 75 0.014
positive regulation of macromolecule metabolic process GO:0010604 149 0.014
rna biosynthetic process GO:0032774 169 0.014
glycosyl compound metabolic process GO:1901657 100 0.014
response to oxygen containing compound GO:1901700 44 0.014
adult locomotory behavior GO:0008344 1 0.014
positive regulation of signaling GO:0023056 66 0.014
positive regulation of gene expression GO:0010628 112 0.014
guanosine containing compound catabolic process GO:1901069 48 0.014
cell part morphogenesis GO:0032990 152 0.014
positive regulation of intracellular transport GO:0032388 2 0.014
purine nucleoside triphosphate catabolic process GO:0009146 72 0.013
neuromuscular junction development GO:0007528 2 0.013
axonogenesis GO:0007409 102 0.013
ribonucleoside triphosphate catabolic process GO:0009203 72 0.013
positive regulation of neuron differentiation GO:0045666 4 0.013
male sex differentiation GO:0046661 86 0.013
cellular ketone metabolic process GO:0042180 14 0.013
negative regulation of multicellular organismal process GO:0051241 236 0.013
negative regulation of biosynthetic process GO:0009890 65 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
response to inorganic substance GO:0010035 50 0.013
ras protein signal transduction GO:0007265 31 0.013
positive regulation of nucleotide metabolic process GO:0045981 28 0.013
cellular protein localization GO:0034613 75 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
organophosphate catabolic process GO:0046434 81 0.013
p38mapk cascade GO:0038066 2 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
protein oligomerization GO:0051259 4 0.013
detection of external stimulus GO:0009581 4 0.012
regulation of nematode larval development GO:0061062 260 0.012
positive regulation of locomotion GO:0040017 42 0.012
cell morphogenesis involved in differentiation GO:0000904 112 0.012
intercellular transport GO:0010496 1 0.012
regulation of oviposition GO:0046662 43 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
cell maturation GO:0048469 26 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
regulation of vesicle mediated transport GO:0060627 27 0.012
microtubule based process GO:0007017 182 0.012
positive regulation of catalytic activity GO:0043085 59 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
pattern specification process GO:0007389 59 0.012
regulation of phosphorylation GO:0042325 45 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
oxoacid metabolic process GO:0043436 47 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.012
embryonic pattern specification GO:0009880 21 0.012
cell matrix adhesion GO:0007160 1 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.012
defense response to other organism GO:0098542 100 0.012
single organism membrane organization GO:0044802 35 0.012
regulation of purine nucleotide metabolic process GO:1900542 37 0.012
regulation of cytoskeleton organization GO:0051493 41 0.012
cell recognition GO:0008037 85 0.011
regulation of biosynthetic process GO:0009889 189 0.011
rna localization GO:0006403 3 0.011
positive regulation of molecular function GO:0044093 61 0.011
detection of abiotic stimulus GO:0009582 4 0.011
regulation of lipid metabolic process GO:0019216 4 0.011
regulation of cellular component movement GO:0051270 62 0.011
nucleus localization GO:0051647 55 0.011
muscle organ development GO:0007517 26 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.011
dendrite development GO:0016358 42 0.011
mechanosensory behavior GO:0007638 25 0.011
negative regulation of neurogenesis GO:0050768 4 0.011
neuromuscular process GO:0050905 1 0.011
intracellular transport GO:0046907 77 0.011
dauer larval development GO:0040024 92 0.011
positive regulation of phosphorylation GO:0042327 27 0.011
regulation of purine nucleotide catabolic process GO:0033121 35 0.011
homeostatic process GO:0042592 51 0.011
digestive tract development GO:0048565 122 0.011
negative regulation of post embryonic development GO:0048581 208 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
cellular response to organic substance GO:0071310 119 0.011
response to endoplasmic reticulum stress GO:0034976 71 0.010
regulation of nervous system development GO:0051960 41 0.010
mitotic nuclear division GO:0007067 89 0.010
axonal fasciculation GO:0007413 79 0.010
regulation of response to wounding GO:1903034 1 0.010
establishment of vesicle localization GO:0051650 23 0.010
negative regulation of vulval development GO:0040027 206 0.010
positive regulation of cell cycle GO:0045787 55 0.010
fertilization GO:0009566 63 0.010
negative regulation of cellular metabolic process GO:0031324 95 0.010

hot-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016