Caenorhabditis elegans

38 known processes

kcc-2 (CELE_H16O14.1)

Protein KCC-2

kcc-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 1634 0.218
Worm
death GO:0016265 547 0.187
embryo development GO:0009790 3052 0.183
Worm
response to external stimulus GO:0009605 289 0.170
multicellular organismal reproductive behavior GO:0033057 384 0.147
multi organism reproductive process GO:0044703 867 0.139
sex differentiation GO:0007548 909 0.138
transport GO:0006810 1093 0.135
single organism reproductive process GO:0044702 1196 0.133
signaling GO:0023052 401 0.125
negative regulation of biological process GO:0048519 567 0.122
single organism localization GO:1902578 518 0.116
organ development GO:0048513 1102 0.115
establishment of localization GO:0051234 1171 0.114
nucleobase containing compound metabolic process GO:0006139 406 0.110
vesicle mediated transport GO:0016192 852 0.108
post embryonic development GO:0009791 2152 0.099
organelle organization GO:0006996 783 0.096
oviposition GO:0018991 364 0.095
receptor mediated endocytosis GO:0006898 715 0.094
programmed cell death GO:0012501 500 0.090
embryo development ending in birth or egg hatching GO:0009792 2992 0.090
Worm
establishment of cell polarity GO:0030010 46 0.089
multi organism reproductive behavior GO:0044705 387 0.087
regulation of biological quality GO:0065008 741 0.084
cell development GO:0048468 696 0.084
multicellular organismal reproductive process GO:0048609 815 0.082
multicellular organism reproduction GO:0032504 819 0.081
signal transduction GO:0007165 317 0.081
regulation of multicellular organismal process GO:0051239 726 0.078
cell cycle process GO:0022402 482 0.077
endocytosis GO:0006897 819 0.076
defense response GO:0006952 296 0.075
cellular response to inorganic substance GO:0071241 3 0.075
apoptotic process GO:0006915 478 0.074
multi multicellular organism process GO:0044706 390 0.074
sexual reproduction GO:0019953 546 0.073
single organism transport GO:0044765 447 0.072
development of primary sexual characteristics GO:0045137 840 0.071
cellular protein modification process GO:0006464 207 0.070
determination of adult lifespan GO:0008340 812 0.070
developmental process involved in reproduction GO:0003006 1165 0.068
maintenance of location GO:0051235 580 0.068
macromolecule localization GO:0033036 771 0.068
organelle fission GO:0048285 363 0.065
single fertilization GO:0007338 61 0.065
establishment of mitotic spindle orientation GO:0000132 28 0.063
lipid localization GO:0010876 573 0.063
cellular protein metabolic process GO:0044267 279 0.062
lipid storage GO:0019915 565 0.062
hermaphrodite genitalia development GO:0040035 734 0.062
behavior GO:0007610 527 0.060
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.060
cell motility GO:0048870 313 0.059
cellular macromolecule biosynthetic process GO:0034645 247 0.056
response to wounding GO:0009611 4 0.055
aging GO:0007568 812 0.055
multi organism behavior GO:0051705 389 0.054
gene expression GO:0010467 412 0.053
negative regulation of multicellular organismal process GO:0051241 236 0.052
pronuclear migration GO:0035046 51 0.052
cell death GO:0008219 547 0.051
protein modification process GO:0036211 207 0.051
protein metabolic process GO:0019538 422 0.050
positive regulation of cellular process GO:0048522 332 0.049
regulation of post embryonic development GO:0048580 260 0.048
cell division GO:0051301 262 0.047
genitalia development GO:0048806 741 0.047
positive regulation of developmental process GO:0051094 408 0.047
cell migration GO:0016477 306 0.046
response to chemical GO:0042221 356 0.046
Mouse
innate immune response GO:0045087 190 0.046
nucleic acid metabolic process GO:0090304 299 0.045
negative regulation of metabolic process GO:0009892 240 0.045
multicellular organismal aging GO:0010259 812 0.045
small molecule metabolic process GO:0044281 186 0.045
regulation of metabolic process GO:0019222 478 0.044
reproductive behavior GO:0019098 387 0.044
regulation of cell projection assembly GO:0060491 3 0.042
striated muscle cell development GO:0055002 157 0.042
establishment of organelle localization GO:0051656 123 0.041
cellular component movement GO:0006928 388 0.041
establishment of localization in cell GO:0051649 318 0.041
reproductive system development GO:0061458 850 0.040
muscle cell development GO:0055001 158 0.040
cellular component morphogenesis GO:0032989 318 0.040
neuroblast division GO:0055057 9 0.040
negative regulation of macromolecule metabolic process GO:0010605 229 0.040
regulation of signaling GO:0023051 172 0.040
response to abiotic stimulus GO:0009628 152 0.039
Mouse
heterocycle catabolic process GO:0046700 119 0.038
regulation of cytoplasmic transport GO:1903649 3 0.038
single organism organelle organization GO:1902589 501 0.038
regulation of reproductive process GO:2000241 66 0.038
regulation of developmental process GO:0050793 684 0.037
generation of neurons GO:0048699 235 0.037
macromolecule modification GO:0043412 218 0.036
neurogenesis GO:0022008 236 0.036
body morphogenesis GO:0010171 620 0.036
spindle localization GO:0051653 51 0.036
gonad development GO:0008406 840 0.035
intracellular signal transduction GO:0035556 96 0.035
nucleus localization GO:0051647 55 0.035
organelle localization GO:0051640 127 0.035
fertilization GO:0009566 63 0.035
carbohydrate metabolic process GO:0005975 34 0.035
microtubule based process GO:0007017 182 0.034
muscle structure development GO:0061061 191 0.034
regulation of cell communication GO:0010646 176 0.034
muscle tissue development GO:0060537 1 0.033
macromolecule biosynthetic process GO:0009059 250 0.033
meiotic cell cycle GO:0051321 335 0.032
organonitrogen compound metabolic process GO:1901564 151 0.032
localization of cell GO:0051674 313 0.032
regulation of nematode larval development GO:0061062 260 0.031
cellular nitrogen compound catabolic process GO:0044270 119 0.031
reproductive structure development GO:0048608 850 0.031
catabolic process GO:0009056 318 0.031
negative regulation of nematode larval development GO:0061064 208 0.030
immune response GO:0006955 192 0.030
establishment of spindle orientation GO:0051294 34 0.030
inductive cell migration GO:0040039 145 0.030
response to organic substance GO:0010033 131 0.030
positive regulation of intracellular transport GO:0032388 2 0.029
regulation of multicellular organism growth GO:0040014 373 0.029
regulation of response to stimulus GO:0048583 243 0.029
cellular macromolecular complex assembly GO:0034622 184 0.029
single organism signaling GO:0044700 401 0.029
meiotic nuclear division GO:0007126 300 0.028
head development GO:0060322 1 0.028
macromolecular complex subunit organization GO:0043933 320 0.028
female gamete generation GO:0007292 254 0.028
negative regulation of cellular process GO:0048523 239 0.028
negative regulation of post embryonic development GO:0048581 208 0.028
growth GO:0040007 562 0.028
Mouse
regulation of gene expression GO:0010468 366 0.027
regulation of multicellular organismal development GO:2000026 317 0.027
cytoskeleton organization GO:0007010 339 0.027
regulation of growth GO:0040008 409 0.027
cell cycle GO:0007049 526 0.027
developmental growth GO:0048589 412 0.027
nuclear migration GO:0007097 54 0.027
negative regulation of gene expression GO:0010629 217 0.027
regulation of cell cycle GO:0051726 194 0.027
multicellular organism growth GO:0035264 385 0.026
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.026
post embryonic organ development GO:0048569 336 0.026
protein complex subunit organization GO:0071822 280 0.026
regulation of primary metabolic process GO:0080090 292 0.026
taxis GO:0042330 128 0.026
asymmetric protein localization GO:0008105 35 0.025
gene silencing GO:0016458 143 0.025
cellular component assembly involved in morphogenesis GO:0010927 183 0.025
negative regulation of vulval development GO:0040027 206 0.025
positive regulation of growth GO:0045927 369 0.024
mitotic cell cycle process GO:1903047 194 0.024
germ cell development GO:0007281 351 0.024
oxoacid metabolic process GO:0043436 47 0.024
cellular component assembly GO:0022607 293 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.024
posttranscriptional gene silencing GO:0016441 143 0.024
cellular biosynthetic process GO:0044249 315 0.024
gene silencing by rna GO:0031047 143 0.024
axon development GO:0061564 163 0.024
regulation of developmental growth GO:0048638 389 0.023
regulation of gene expression epigenetic GO:0040029 163 0.023
macromolecular complex assembly GO:0065003 193 0.023
mechanosensory behavior GO:0007638 25 0.023
positive regulation of developmental growth GO:0048639 354 0.023
actin cytoskeleton organization GO:0030036 184 0.023
regulation of behavior GO:0050795 97 0.023
establishment of mitotic spindle localization GO:0040001 41 0.022
organic substance biosynthetic process GO:1901576 323 0.022
myosin filament assembly GO:0031034 138 0.022
response to external biotic stimulus GO:0043207 101 0.022
protein complex assembly GO:0006461 186 0.022
striated muscle cell differentiation GO:0051146 158 0.022
establishment or maintenance of cell polarity GO:0007163 63 0.022
establishment of spindle localization GO:0051293 51 0.022
cellular component biogenesis GO:0044085 297 0.021
establishment of nucleus localization GO:0040023 55 0.021
regulation of pharyngeal pumping GO:0043051 36 0.021
organic substance catabolic process GO:1901575 294 0.021
single organism behavior GO:0044708 83 0.021
Mouse
regulation of multi organism process GO:0043900 69 0.021
protein phosphorylation GO:0006468 85 0.021
carbohydrate derivative metabolic process GO:1901135 141 0.021
positive regulation of multicellular organism growth GO:0040018 352 0.021
gamete generation GO:0007276 461 0.021
regulation of locomotion GO:0040012 161 0.021
regulation of signal transduction GO:0009966 135 0.021
cell surface receptor signaling pathway GO:0007166 149 0.020
response to heat GO:0009408 50 0.020
protein complex biogenesis GO:0070271 186 0.020
cellular localization GO:0051641 360 0.020
cellular protein complex assembly GO:0043623 178 0.020
rna interference GO:0016246 137 0.020
cellular catabolic process GO:0044248 199 0.019
carboxylic acid metabolic process GO:0019752 34 0.019
organic acid metabolic process GO:0006082 47 0.019
myofibril assembly GO:0030239 154 0.019
muscle cell differentiation GO:0042692 171 0.019
skeletal muscle organ development GO:0060538 3 0.019
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.019
macromolecule catabolic process GO:0009057 202 0.019
cell fate commitment GO:0045165 139 0.019
neurological system process GO:0050877 53 0.019
Mouse
phagocytosis GO:0006909 115 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.018
response to oxygen containing compound GO:1901700 44 0.018
rna metabolic process GO:0016070 228 0.018
regulation of cellular metabolic process GO:0031323 305 0.018
protein catabolic process GO:0030163 162 0.018
transmembrane transport GO:0055085 110 0.018
negative regulation of developmental process GO:0051093 227 0.018
regulation of nucleocytoplasmic transport GO:0046822 3 0.018
response to biotic stimulus GO:0009607 101 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.018
regulation of molecular function GO:0065009 89 0.018
pattern specification process GO:0007389 59 0.018
posttranscriptional gene silencing by rna GO:0035194 143 0.018
regulation of cell division GO:0051302 142 0.018
response to inorganic substance GO:0010035 50 0.018
aromatic compound catabolic process GO:0019439 116 0.018
regulation of lipid metabolic process GO:0019216 4 0.017
cytokinesis GO:0000910 80 0.017
positive regulation of multicellular organismal process GO:0051240 417 0.017
neuron projection development GO:0031175 187 0.017
organelle assembly GO:0070925 214 0.017
organic cyclic compound catabolic process GO:1901361 119 0.017
neuron differentiation GO:0030182 217 0.017
oogenesis GO:0048477 229 0.017
response to acid chemical GO:0001101 4 0.017
regulation of cell cycle process GO:0010564 145 0.017
response to bacterium GO:0009617 86 0.017
regulation of macromolecule biosynthetic process GO:0010556 189 0.016
meiotic cell cycle process GO:1903046 170 0.016
response to temperature stimulus GO:0009266 66 0.016
Mouse
oxidation reduction process GO:0055114 59 0.016
phagocytosis engulfment GO:0006911 98 0.016
striated muscle myosin thick filament assembly GO:0071688 138 0.016
molting cycle GO:0042303 281 0.016
single organism carbohydrate metabolic process GO:0044723 29 0.016
cellular response to abiotic stimulus GO:0071214 4 0.016
peptidyl amino acid modification GO:0018193 58 0.016
nervous system development GO:0007399 253 0.016
apoptotic cell clearance GO:0043277 111 0.016
negative regulation of biosynthetic process GO:0009890 65 0.016
biosynthetic process GO:0009058 323 0.016
regeneration GO:0031099 4 0.015
epithelial tube morphogenesis GO:0060562 1 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.015
metal ion transport GO:0030001 49 0.015
sensory organ morphogenesis GO:0090596 2 0.015
myosin filament organization GO:0031033 138 0.015
cellular ketone metabolic process GO:0042180 14 0.015
chromosome segregation GO:0007059 180 0.015
actomyosin structure organization GO:0031032 154 0.015
nucleoside triphosphate catabolic process GO:0009143 72 0.015
vulval development GO:0040025 333 0.015
positive regulation of neuron differentiation GO:0045666 4 0.015
positive regulation of metabolic process GO:0009893 187 0.015
cellular response to metal ion GO:0071248 3 0.015
regulation of localization GO:0032879 194 0.014
synaptic transmission GO:0007268 106 0.014
dauer larval development GO:0040024 92 0.014
membrane organization GO:0061024 135 0.014
regulation of vulval development GO:0040028 248 0.014
regulation of biosynthetic process GO:0009889 189 0.014
neuron recognition GO:0008038 83 0.014
regulation of response to wounding GO:1903034 1 0.014
intracellular transport GO:0046907 77 0.014
single organism cellular localization GO:1902580 72 0.014
ion transport GO:0006811 113 0.014
regulation of protein targeting GO:1903533 3 0.013
glycosyl compound metabolic process GO:1901657 100 0.013
phosphate containing compound metabolic process GO:0006796 232 0.013
regulation of protein import into nucleus GO:0042306 3 0.013
hormone transport GO:0009914 2 0.013
mitotic spindle organization GO:0007052 81 0.013
glycoprotein metabolic process GO:0009100 29 0.012
cellular response to chemical stimulus GO:0070887 129 0.012
purine nucleotide catabolic process GO:0006195 75 0.012
protein localization GO:0008104 205 0.012
response to food GO:0032094 9 0.012
neuron projection morphogenesis GO:0048812 114 0.012
regulation of cellular biosynthetic process GO:0031326 189 0.012
apical junction assembly GO:0043297 1 0.012
positive regulation of protein transport GO:0051222 4 0.012
monovalent inorganic cation transport GO:0015672 33 0.012
purine ribonucleoside metabolic process GO:0046128 92 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.011
cell type specific apoptotic process GO:0097285 4 0.011
purine nucleoside metabolic process GO:0042278 92 0.011
aromatic compound biosynthetic process GO:0019438 192 0.011
membrane invagination GO:0010324 98 0.011
defense response to bacterium GO:0042742 86 0.011
cation transport GO:0006812 78 0.011
regulation of cell death GO:0010941 65 0.011
engulfment of apoptotic cell GO:0043652 94 0.011
actin filament based process GO:0030029 191 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.011
rna localization GO:0006403 3 0.011
cell projection organization GO:0030030 231 0.011
nucleoside phosphate catabolic process GO:1901292 77 0.011
single organism biosynthetic process GO:0044711 91 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
regulation of oviposition GO:0046662 43 0.011
meiotic chromosome segregation GO:0045132 139 0.011
purine ribonucleoside catabolic process GO:0046130 75 0.011
negative regulation of cellular biosynthetic process GO:0031327 65 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.011
establishment of vesicle localization GO:0051650 23 0.011
chemotaxis GO:0006935 120 0.011
pigmentation GO:0043473 2 0.011
regulation of nuclear division GO:0051783 115 0.010
cellular response to stress GO:0033554 162 0.010
directional locomotion GO:0033058 14 0.010
cuticle development GO:0042335 100 0.010
single organism intracellular transport GO:1902582 70 0.010
system process GO:0003008 136 0.010
Mouse
pharyngeal pumping GO:0043050 58 0.010

kcc-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.012