Caenorhabditis elegans

43 known processes

ace-3 (CELE_Y48B6A.8)

Protein ACE-3

ace-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
acetylcholine catabolic process GO:0006581 4 0.925
cellular biogenic amine catabolic process GO:0042402 1 0.836
Fly
neurotransmitter catabolic process GO:0042135 4 0.826
acetylcholine metabolic process GO:0008291 4 0.809
acetate ester metabolic process GO:1900619 4 0.799
post embryonic development GO:0009791 2152 0.662
organ development GO:0048513 1102 0.624
Mouse
locomotion GO:0040011 1634 0.486
regulation of cellular metabolic process GO:0031323 305 0.460
Mouse
cellular component morphogenesis GO:0032989 318 0.408
Zebrafish
cellular response to chemical stimulus GO:0070887 129 0.393
Zebrafish
cell cell signaling GO:0007267 118 0.368
neuron differentiation GO:0030182 217 0.350
Zebrafish
organelle organization GO:0006996 783 0.349
Zebrafish
taxis GO:0042330 128 0.347
Fly
neurogenesis GO:0022008 236 0.345
Zebrafish
striated muscle cell differentiation GO:0051146 158 0.314
Zebrafish
establishment of localization GO:0051234 1171 0.312
Mouse
single organism signaling GO:0044700 401 0.305
nervous system development GO:0007399 253 0.290
Zebrafish
single organism localization GO:1902578 518 0.284
Mouse
striated muscle cell development GO:0055002 157 0.280
Zebrafish
cell development GO:0048468 696 0.275
Zebrafish
cytoskeleton organization GO:0007010 339 0.271
Zebrafish
endocytosis GO:0006897 819 0.262
Mouse
macromolecule biosynthetic process GO:0009059 250 0.252
Mouse
regulation of locomotion GO:0040012 161 0.248
regulation of metabolic process GO:0019222 478 0.248
Mouse
neuron development GO:0048666 199 0.247
Zebrafish
actin filament based process GO:0030029 191 0.237
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 2992 0.236
muscle cell differentiation GO:0042692 171 0.227
Zebrafish
anatomical structure formation involved in morphogenesis GO:0048646 250 0.224
Zebrafish
regulation of macromolecule metabolic process GO:0060255 421 0.216
Mouse
muscle cell development GO:0055001 158 0.212
Zebrafish
protein complex subunit organization GO:0071822 280 0.208
Mouse
actin cytoskeleton organization GO:0030036 184 0.207
Zebrafish
generation of neurons GO:0048699 235 0.206
Zebrafish
determination of adult lifespan GO:0008340 812 0.206
Worm
muscle structure development GO:0061061 191 0.202
Zebrafish
embryo development GO:0009790 3052 0.199
single organism organelle organization GO:1902589 501 0.198
Zebrafish
cellular response to organic substance GO:0071310 119 0.192
Zebrafish
response to external stimulus GO:0009605 289 0.188
Fly
response to chemical GO:0042221 356 0.178
Zebrafish
regulation of biological quality GO:0065008 741 0.178
transport GO:0006810 1093 0.175
Mouse
vesicle mediated transport GO:0016192 852 0.174
Mouse
multicellular organismal aging GO:0010259 812 0.168
Worm
cellular component assembly involved in morphogenesis GO:0010927 183 0.165
Zebrafish
body morphogenesis GO:0010171 620 0.160
organonitrogen compound catabolic process GO:1901565 90 0.157
Fly
organic substance biosynthetic process GO:1901576 323 0.157
Mouse
actomyosin structure organization GO:0031032 154 0.155
Zebrafish
aging GO:0007568 812 0.150
Worm
sex differentiation GO:0007548 909 0.148
biosynthetic process GO:0009058 323 0.147
Mouse
cellular component biogenesis GO:0044085 297 0.143
Zebrafish Mouse
response to acid chemical GO:0001101 4 0.143
Zebrafish
catabolic process GO:0009056 318 0.142
cellular component assembly GO:0022607 293 0.133
Zebrafish Mouse
tissue development GO:0009888 112 0.129
Mouse
response to abiotic stimulus GO:0009628 152 0.124
Fly
single organism reproductive process GO:0044702 1196 0.123
regulation of developmental process GO:0050793 684 0.120
response to organic substance GO:0010033 131 0.117
Zebrafish
organelle assembly GO:0070925 214 0.116
Zebrafish
growth GO:0040007 562 0.116
multicellular organism reproduction GO:0032504 819 0.110
gamete generation GO:0007276 461 0.109
myofibril assembly GO:0030239 154 0.108
Zebrafish
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.108
macromolecular complex subunit organization GO:0043933 320 0.107
Mouse
neuromuscular junction development GO:0007528 2 0.101
Zebrafish
receptor mediated endocytosis GO:0006898 715 0.101
Mouse
regulation of backward locomotion GO:0043058 8 0.098
multi organism reproductive process GO:0044703 867 0.097
protein complex biogenesis GO:0070271 186 0.096
Mouse
signaling GO:0023052 401 0.095
single organism transport GO:0044765 447 0.093
Mouse
negative regulation of biological process GO:0048519 567 0.090
developmental process involved in reproduction GO:0003006 1165 0.090
synaptic transmission GO:0007268 106 0.086
germ cell development GO:0007281 351 0.085
multicellular organismal reproductive process GO:0048609 815 0.085
axon development GO:0061564 163 0.083
macromolecular complex assembly GO:0065003 193 0.082
Mouse
regulation of primary metabolic process GO:0080090 292 0.082
organonitrogen compound metabolic process GO:1901564 151 0.081
Fly
regulation of signaling GO:0023051 172 0.079
Mouse
multi multicellular organism process GO:0044706 390 0.078
protein complex assembly GO:0006461 186 0.077
Mouse
receptor metabolic process GO:0043112 6 0.076
Mouse
response to organonitrogen compound GO:0010243 15 0.073
Zebrafish
synaptic transmission cholinergic GO:0007271 21 0.072
Worm
development of primary sexual characteristics GO:0045137 840 0.072
nucleobase containing compound metabolic process GO:0006139 406 0.070
organic substance catabolic process GO:1901575 294 0.070
neurotransmitter metabolic process GO:0042133 6 0.070
reproductive system development GO:0061458 850 0.069
energy taxis GO:0009453 3 0.068
Fly
cell fate commitment GO:0045165 139 0.067
organism emergence from protective structure GO:0071684 48 0.067
macromolecule localization GO:0033036 771 0.067
lipid localization GO:0010876 573 0.065
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.064
sexual reproduction GO:0019953 546 0.063
regulation of gene expression GO:0010468 366 0.061
cell surface receptor signaling pathway GO:0007166 149 0.061
cellular catabolic process GO:0044248 199 0.059
positive regulation of developmental process GO:0051094 408 0.059
cellular biosynthetic process GO:0044249 315 0.059
maintenance of location GO:0051235 580 0.059
regulation of cellular biosynthetic process GO:0031326 189 0.059
lipid storage GO:0019915 565 0.058
single organism catabolic process GO:0044712 129 0.058
amine metabolic process GO:0009308 15 0.058
Fly
positive regulation of rna biosynthetic process GO:1902680 102 0.058
head development GO:0060322 1 0.058
amine catabolic process GO:0009310 1 0.057
Fly
regulation of multicellular organism growth GO:0040014 373 0.055
cell cycle process GO:0022402 482 0.054
reproductive structure development GO:0048608 850 0.054
gonad development GO:0008406 840 0.054
cellular component movement GO:0006928 388 0.053
regulation of multicellular organismal development GO:2000026 317 0.053
small molecule metabolic process GO:0044281 186 0.053
Fly
regulation of rna metabolic process GO:0051252 173 0.053
transcription from rna polymerase ii promoter GO:0006366 149 0.051
developmental growth GO:0048589 412 0.051
regulation of multicellular organismal process GO:0051239 726 0.050
cell morphogenesis GO:0000902 163 0.050
behavior GO:0007610 527 0.050
negative regulation of macromolecule metabolic process GO:0010605 229 0.050
synaptic target recognition GO:0008039 3 0.049
cellular amine metabolic process GO:0044106 15 0.049
Fly
axonogenesis GO:0007409 102 0.049
regulation of growth GO:0040008 409 0.049
neuron projection development GO:0031175 187 0.048
regulation of developmental growth GO:0048638 389 0.048
synapse organization GO:0050808 24 0.048
Zebrafish
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.046
regulation of biosynthetic process GO:0009889 189 0.046
regulation of cellular component organization GO:0051128 248 0.046
response to oxygen containing compound GO:1901700 44 0.046
Zebrafish
negative regulation of gene expression GO:0010629 217 0.046
negative regulation of cellular process GO:0048523 239 0.045
positive regulation of multicellular organism growth GO:0040018 352 0.045
signal transduction GO:0007165 317 0.044
positive regulation of growth GO:0045927 369 0.044
regulation of rna biosynthetic process GO:2001141 165 0.043
localization of cell GO:0051674 313 0.043
cell division GO:0051301 262 0.043
organic cyclic compound biosynthetic process GO:1901362 195 0.042
sensory organ morphogenesis GO:0090596 2 0.042
rna biosynthetic process GO:0032774 169 0.042
gene expression GO:0010467 412 0.042
protein metabolic process GO:0019538 422 0.041
aromatic compound biosynthetic process GO:0019438 192 0.041
cellular nitrogen compound biosynthetic process GO:0044271 192 0.041
heterocycle biosynthetic process GO:0018130 187 0.039
positive regulation of nucleic acid templated transcription GO:1903508 102 0.039
multi organism reproductive behavior GO:0044705 387 0.039
cellular macromolecule biosynthetic process GO:0034645 247 0.039
negative regulation of metabolic process GO:0009892 240 0.038
multicellular organism growth GO:0035264 385 0.038
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.038
response to endogenous stimulus GO:0009719 33 0.038
Zebrafish
positive regulation of rna metabolic process GO:0051254 103 0.038
death GO:0016265 547 0.037
muscle organ morphogenesis GO:0048644 4 0.037
female gamete generation GO:0007292 254 0.037
response to wounding GO:0009611 4 0.037
cell death GO:0008219 547 0.037
cell migration GO:0016477 306 0.036
multi organism behavior GO:0051705 389 0.036
nucleic acid metabolic process GO:0090304 299 0.035
transcription dna templated GO:0006351 168 0.035
chemotaxis GO:0006935 120 0.035
oviposition GO:0018991 364 0.035
cell cycle GO:0007049 526 0.034
positive regulation of cellular process GO:0048522 332 0.034
regulation of organelle organization GO:0033043 164 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.034
regulation of macromolecule biosynthetic process GO:0010556 189 0.034
positive regulation of transcription dna templated GO:0045893 102 0.034
nucleic acid templated transcription GO:0097659 169 0.034
multicellular organismal reproductive behavior GO:0033057 384 0.033
hermaphrodite genitalia development GO:0040035 734 0.033
multicellular organismal movement GO:0050879 2 0.033
positive regulation of multicellular organismal process GO:0051240 417 0.033
hatching GO:0035188 48 0.033
tube development GO:0035295 126 0.032
nucleobase containing compound biosynthetic process GO:0034654 184 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.032
rna metabolic process GO:0016070 228 0.032
neuron projection morphogenesis GO:0048812 114 0.032
cellular protein complex assembly GO:0043623 178 0.032
reproductive behavior GO:0019098 387 0.032
oogenesis GO:0048477 229 0.031
positive regulation of developmental growth GO:0048639 354 0.031
regulation of nitrogen compound metabolic process GO:0051171 222 0.031
apoptotic process GO:0006915 478 0.031
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.031
genitalia development GO:0048806 741 0.030
cellular macromolecular complex assembly GO:0034622 184 0.030
protein oligomerization GO:0051259 4 0.030
Mouse
organic hydroxy compound catabolic process GO:1901616 4 0.030
Fly
cellular response to stress GO:0033554 162 0.030
cell recognition GO:0008037 85 0.030
neuroblast fate determination GO:0007400 1 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.029
positive regulation of gene expression GO:0010628 112 0.029
regulation of neuron differentiation GO:0045664 40 0.029
positive regulation of neuron differentiation GO:0045666 4 0.029
cell motility GO:0048870 313 0.028
phosphorus metabolic process GO:0006793 232 0.028
response to nitrogen compound GO:1901698 25 0.028
Zebrafish
regulation of synapse structure and activity GO:0050803 13 0.027
Zebrafish
striated muscle myosin thick filament assembly GO:0071688 138 0.027
macromolecule catabolic process GO:0009057 202 0.027
epithelial tube morphogenesis GO:0060562 1 0.027
positive regulation of cellular biosynthetic process GO:0031328 109 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.026
cellular response to oxygen containing compound GO:1901701 21 0.026
Zebrafish
programmed cell death GO:0012501 500 0.026
membrane organization GO:0061024 135 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.025
positive regulation of metabolic process GO:0009893 187 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.025
protein catabolic process GO:0030163 162 0.025
negative regulation of cellular biosynthetic process GO:0031327 65 0.025
backward locomotion GO:0043057 11 0.025
cell part morphogenesis GO:0032990 152 0.025
negative regulation of biosynthetic process GO:0009890 65 0.025
tube morphogenesis GO:0035239 79 0.025
regulation of nucleic acid templated transcription GO:1903506 165 0.024
regulation of transcription dna templated GO:0006355 164 0.024
digestive tract development GO:0048565 122 0.024
cell projection organization GO:0030030 231 0.024
apoptotic cell clearance GO:0043277 111 0.024
macromolecule modification GO:0043412 218 0.024
molting cycle GO:0042303 281 0.024
cell morphogenesis involved in differentiation GO:0000904 112 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.023
cell projection morphogenesis GO:0048858 148 0.023
regulation of cell cycle GO:0051726 194 0.023
myosin filament organization GO:0031033 138 0.023
embryonic morphogenesis GO:0048598 152 0.023
regulation of anatomical structure morphogenesis GO:0022603 51 0.023
negative regulation of cellular metabolic process GO:0031324 95 0.023
neuron recognition GO:0008038 83 0.023
regulation of cell communication GO:0010646 176 0.023
digestive system development GO:0055123 122 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.022
positive regulation of cellular metabolic process GO:0031325 178 0.022
phagocytosis GO:0006909 115 0.022
regulation of localization GO:0032879 194 0.022
cellular protein metabolic process GO:0044267 279 0.022
positive regulation of biosynthetic process GO:0009891 109 0.022
negative regulation of developmental process GO:0051093 227 0.021
canonical wnt signaling pathway GO:0060070 3 0.021
myosin filament assembly GO:0031034 138 0.021
protein localization GO:0008104 205 0.021
cellular response to unfolded protein GO:0034620 71 0.021
negative regulation of transcription dna templated GO:0045892 53 0.021
cuticle development GO:0042335 100 0.021
muscle tissue development GO:0060537 1 0.021
establishment of localization in cell GO:0051649 318 0.020
cellular response to topologically incorrect protein GO:0035967 76 0.020
organic hydroxy compound metabolic process GO:1901615 25 0.020
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.020
protein tetramerization GO:0051262 1 0.019
Mouse
adult behavior GO:0030534 3 0.019
dauer larval development GO:0040024 92 0.019
defense response GO:0006952 296 0.019
cellular protein modification process GO:0006464 207 0.019
regulation of neurotransmitter levels GO:0001505 36 0.019
purine nucleotide metabolic process GO:0006163 95 0.019
axon guidance GO:0007411 82 0.018
cellular localization GO:0051641 360 0.018
regulation of cell cycle process GO:0010564 145 0.018
defense response to bacterium GO:0042742 86 0.018
phagocytosis engulfment GO:0006911 98 0.018
posttranscriptional regulation of gene expression GO:0010608 166 0.018
regeneration GO:0031099 4 0.017
phosphorylation GO:0016310 116 0.017
negative regulation of rna biosynthetic process GO:1902679 53 0.017
negative regulation of rna metabolic process GO:0051253 53 0.017
inductive cell migration GO:0040039 145 0.017
regulation of post embryonic development GO:0048580 260 0.017
negative regulation of nucleic acid templated transcription GO:1903507 53 0.017
regulation of cell development GO:0060284 49 0.016
defense response to other organism GO:0098542 100 0.016
cell type specific apoptotic process GO:0097285 4 0.016
developmental cell growth GO:0048588 39 0.016
regulation of cell division GO:0051302 142 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
mitotic cell cycle process GO:1903047 194 0.016
meiotic cell cycle GO:0051321 335 0.016
regulation of cation channel activity GO:2001257 3 0.016
vulval development GO:0040025 333 0.016
regulation of organ morphogenesis GO:2000027 4 0.016
response to external biotic stimulus GO:0043207 101 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
adult locomotory behavior GO:0008344 1 0.015
positive regulation of neurogenesis GO:0050769 4 0.015
nucleobase containing small molecule metabolic process GO:0055086 115 0.015
membrane invagination GO:0010324 98 0.015
immune response GO:0006955 192 0.015
positive regulation of macromolecule metabolic process GO:0010604 149 0.015
regulation of cell proliferation GO:0042127 105 0.015
engulfment of apoptotic cell GO:0043652 94 0.015
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.015
collagen and cuticulin based cuticle development GO:0040002 99 0.015
regulation of synapse assembly GO:0051963 2 0.015
response to topologically incorrect protein GO:0035966 82 0.015
protein modification process GO:0036211 207 0.015
response to bacterium GO:0009617 86 0.014
response to other organism GO:0051707 101 0.014
peptidyl tyrosine phosphorylation GO:0018108 2 0.014
post embryonic organ development GO:0048569 336 0.014
neuron projection guidance GO:0097485 82 0.014
regulation of cytoskeleton organization GO:0051493 41 0.014
intracellular receptor signaling pathway GO:0030522 2 0.014
regulation of stem cell differentiation GO:2000736 1 0.014
ribonucleotide metabolic process GO:0009259 99 0.014
regulation of meiotic cell cycle GO:0051445 136 0.014
carbohydrate derivative metabolic process GO:1901135 141 0.014
negative regulation of multicellular organismal process GO:0051241 236 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
axonal fasciculation GO:0007413 79 0.014
negative regulation of neurogenesis GO:0050768 4 0.013
meiotic nuclear division GO:0007126 300 0.013
regulation of neurogenesis GO:0050767 40 0.013
response to unfolded protein GO:0006986 71 0.013
purine containing compound metabolic process GO:0072521 95 0.013
single organism behavior GO:0044708 83 0.013
actin cytoskeleton reorganization GO:0031532 4 0.013
organ morphogenesis GO:0009887 67 0.013
ribose phosphate metabolic process GO:0019693 99 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
ion transmembrane transport GO:0034220 91 0.013
organophosphate metabolic process GO:0019637 125 0.013
ribonucleoprotein complex assembly GO:0022618 4 0.013
nematode male tail tip morphogenesis GO:0045138 77 0.013
regulation of nematode larval development GO:0061062 260 0.013
regulation of gastrulation GO:0010470 4 0.013
regulation of nervous system development GO:0051960 41 0.013
cytokinesis GO:0000910 80 0.012
glycosyl compound metabolic process GO:1901657 100 0.012
wnt signaling pathway GO:0016055 27 0.012
chromosome segregation GO:0007059 180 0.012
cell growth GO:0016049 44 0.012
organelle fission GO:0048285 363 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
developmental growth involved in morphogenesis GO:0060560 37 0.012
small gtpase mediated signal transduction GO:0007264 32 0.012
regulation of nuclear division GO:0051783 115 0.012
regulation of cell migration GO:0030334 55 0.012
organic cyclic compound catabolic process GO:1901361 119 0.012
cell proliferation GO:0008283 116 0.012
regulation of meiosis GO:0040020 94 0.012
gene silencing GO:0016458 143 0.012
regulation of response to stimulus GO:0048583 243 0.011
ribonucleoside triphosphate metabolic process GO:0009199 87 0.011
single organism cellular localization GO:1902580 72 0.011
regulation of axonogenesis GO:0050770 24 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.011
regulation of cellular component size GO:0032535 40 0.011
spindle localization GO:0051653 51 0.011
microtubule based process GO:0007017 182 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
epithelial cell proliferation GO:0050673 1 0.011
regulation of gene expression epigenetic GO:0040029 163 0.011
nucleoside phosphate metabolic process GO:0006753 108 0.011
organic substance transport GO:0071702 113 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
development of primary male sexual characteristics GO:0046546 4 0.011
digestive tract morphogenesis GO:0048546 76 0.011
regulation of cell differentiation GO:0045595 81 0.011
protein phosphorylation GO:0006468 85 0.011
aromatic compound catabolic process GO:0019439 116 0.011
neuron projection extension GO:1990138 37 0.011
regulation of cell motility GO:2000145 57 0.011
skeletal muscle organ development GO:0060538 3 0.011
regulation of extent of cell growth GO:0061387 20 0.011
purine ribonucleotide metabolic process GO:0009150 95 0.011
nucleotide catabolic process GO:0009166 77 0.011
feeding behavior GO:0007631 70 0.010
response to biotic stimulus GO:0009607 101 0.010
mesoderm development GO:0007498 27 0.010
small molecule catabolic process GO:0044282 9 0.010
Fly
regulation of cell morphogenesis GO:0022604 40 0.010
regulation of canonical wnt signaling pathway GO:0060828 1 0.010
negative regulation of cellular component organization GO:0051129 33 0.010
axon extension GO:0048675 37 0.010

ace-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.019