Caenorhabditis elegans

52 known processes

peb-1 (CELE_T14F9.4)

Protein PEB-1

peb-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
developmental process involved in reproduction GO:0003006 1165 0.650
post embryonic development GO:0009791 2152 0.577
nucleic acid metabolic process GO:0090304 299 0.554
cellular biosynthetic process GO:0044249 315 0.550
cellular macromolecule biosynthetic process GO:0034645 247 0.544
embryo development ending in birth or egg hatching GO:0009792 2992 0.543
cellular response to chemical stimulus GO:0070887 129 0.541
neuron projection development GO:0031175 187 0.538
embryo development GO:0009790 3052 0.538
positive regulation of cellular process GO:0048522 332 0.526
negative regulation of nematode larval development GO:0061064 208 0.504
regulation of gene expression GO:0010468 366 0.502
regulation of multicellular organismal development GO:2000026 317 0.484
heterocycle biosynthetic process GO:0018130 187 0.476
regulation of macromolecule biosynthetic process GO:0010556 189 0.457
nucleic acid templated transcription GO:0097659 169 0.447
regulation of developmental process GO:0050793 684 0.438
single organism reproductive process GO:0044702 1196 0.436
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.419
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.411
regulation of macromolecule metabolic process GO:0060255 421 0.408
neurogenesis GO:0022008 236 0.392
regulation of multicellular organismal process GO:0051239 726 0.391
rna metabolic process GO:0016070 228 0.383
gene expression GO:0010467 412 0.383
cellular nitrogen compound biosynthetic process GO:0044271 192 0.380
macromolecule biosynthetic process GO:0009059 250 0.376
organic cyclic compound biosynthetic process GO:1901362 195 0.375
regulation of biosynthetic process GO:0009889 189 0.365
axon development GO:0061564 163 0.364
multicellular organismal aging GO:0010259 812 0.352
aging GO:0007568 812 0.351
biosynthetic process GO:0009058 323 0.348
regulation of nucleic acid templated transcription GO:1903506 165 0.340
regulation of metabolic process GO:0019222 478 0.334
reproductive system development GO:0061458 850 0.319
determination of adult lifespan GO:0008340 812 0.319
negative regulation of vulval development GO:0040027 206 0.314
reproductive structure development GO:0048608 850 0.311
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.310
negative regulation of biological process GO:0048519 567 0.304
positive regulation of multicellular organismal process GO:0051240 417 0.302
regulation of cellular metabolic process GO:0031323 305 0.301
cellular response to organic substance GO:0071310 119 0.300
cellular component morphogenesis GO:0032989 318 0.297
organic substance biosynthetic process GO:1901576 323 0.293
regulation of rna biosynthetic process GO:2001141 165 0.291
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.289
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.286
genitalia development GO:0048806 741 0.285
single organism signaling GO:0044700 401 0.284
cell development GO:0048468 696 0.283
regulation of vulval development GO:0040028 248 0.276
neuron development GO:0048666 199 0.274
rna biosynthetic process GO:0032774 169 0.268
behavior GO:0007610 527 0.267
cellular component movement GO:0006928 388 0.267
cellular response to endogenous stimulus GO:0071495 32 0.264
regulation of nitrogen compound metabolic process GO:0051171 222 0.260
vulval development GO:0040025 333 0.254
neuron differentiation GO:0030182 217 0.250
multicellular organism reproduction GO:0032504 819 0.248
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.248
response to external stimulus GO:0009605 289 0.244
sex differentiation GO:0007548 909 0.232
positive regulation of metabolic process GO:0009893 187 0.231
molting cycle GO:0042303 281 0.231
regulation of nematode larval development GO:0061062 260 0.227
multicellular organismal reproductive process GO:0048609 815 0.226
negative regulation of transcription dna templated GO:0045892 53 0.224
cell projection morphogenesis GO:0048858 148 0.221
aromatic compound biosynthetic process GO:0019438 192 0.220
transcription dna templated GO:0006351 168 0.217
signal transduction GO:0007165 317 0.213
locomotion GO:0040011 1634 0.213
axon guidance GO:0007411 82 0.209
gastrulation GO:0007369 58 0.205
negative regulation of post embryonic development GO:0048581 208 0.201
generation of neurons GO:0048699 235 0.201
cell projection organization GO:0030030 231 0.201
development of primary sexual characteristics GO:0045137 840 0.198
signaling GO:0023052 401 0.191
regulation of cellular biosynthetic process GO:0031326 189 0.191
tube development GO:0035295 126 0.186
post embryonic organ development GO:0048569 336 0.185
positive regulation of growth GO:0045927 369 0.172
nucleobase containing compound metabolic process GO:0006139 406 0.170
negative regulation of macromolecule metabolic process GO:0010605 229 0.169
neuron projection morphogenesis GO:0048812 114 0.169
gonad development GO:0008406 840 0.168
taxis GO:0042330 128 0.166
positive regulation of nucleic acid templated transcription GO:1903508 102 0.162
response to chemical GO:0042221 356 0.155
positive regulation of rna biosynthetic process GO:1902680 102 0.153
positive regulation of cellular biosynthetic process GO:0031328 109 0.151
cell part morphogenesis GO:0032990 152 0.150
developmental growth GO:0048589 412 0.149
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.148
neuron projection guidance GO:0097485 82 0.148
negative regulation of response to stimulus GO:0048585 73 0.144
hermaphrodite genitalia development GO:0040035 734 0.143
macromolecule localization GO:0033036 771 0.142
regulation of transcription dna templated GO:0006355 164 0.141
regulation of developmental growth GO:0048638 389 0.140
regulation of rna metabolic process GO:0051252 173 0.139
transport GO:0006810 1093 0.136
body morphogenesis GO:0010171 620 0.133
cell fate commitment GO:0045165 139 0.132
death GO:0016265 547 0.130
negative regulation of cellular process GO:0048523 239 0.129
enzyme linked receptor protein signaling pathway GO:0007167 50 0.129
negative regulation of biosynthetic process GO:0009890 65 0.128
negative regulation of developmental process GO:0051093 227 0.128
single organism localization GO:1902578 518 0.127
regulation of post embryonic development GO:0048580 260 0.126
positive regulation of rna metabolic process GO:0051254 103 0.126
organ development GO:0048513 1102 0.125
nucleobase containing compound biosynthetic process GO:0034654 184 0.121
response to organic substance GO:0010033 131 0.120
regulation of neurogenesis GO:0050767 40 0.120
regulation of signaling GO:0023051 172 0.118
cell morphogenesis GO:0000902 163 0.118
positive regulation of gene expression GO:0010628 112 0.116
nervous system development GO:0007399 253 0.116
growth GO:0040007 562 0.115
regulation of growth GO:0040008 409 0.114
vesicle mediated transport GO:0016192 852 0.114
negative regulation of metabolic process GO:0009892 240 0.113
negative regulation of gene expression GO:0010629 217 0.112
positive regulation of developmental growth GO:0048639 354 0.111
protein metabolic process GO:0019538 422 0.111
positive regulation of transcription dna templated GO:0045893 102 0.110
positive regulation of macromolecule metabolic process GO:0010604 149 0.107
positive regulation of cellular metabolic process GO:0031325 178 0.106
regulation of multicellular organism growth GO:0040014 373 0.105
multicellular organism growth GO:0035264 385 0.103
positive regulation of multicellular organism growth GO:0040018 352 0.103
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.103
lipid localization GO:0010876 573 0.103
negative regulation of cellular metabolic process GO:0031324 95 0.102
regulation of signal transduction GO:0009966 135 0.101
cell morphogenesis involved in differentiation GO:0000904 112 0.100
reproductive behavior GO:0019098 387 0.100
multi organism reproductive process GO:0044703 867 0.099
programmed cell death GO:0012501 500 0.099
pattern specification process GO:0007389 59 0.097
cellular protein modification process GO:0006464 207 0.097
axonogenesis GO:0007409 102 0.097
negative regulation of multicellular organismal process GO:0051241 236 0.097
organelle organization GO:0006996 783 0.096
multi organism reproductive behavior GO:0044705 387 0.095
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.093
regulation of biological quality GO:0065008 741 0.090
maintenance of location GO:0051235 580 0.090
apoptotic process GO:0006915 478 0.090
germ cell development GO:0007281 351 0.089
positive regulation of developmental process GO:0051094 408 0.087
receptor mediated endocytosis GO:0006898 715 0.083
tissue development GO:0009888 112 0.082
multicellular organismal reproductive behavior GO:0033057 384 0.081
cell death GO:0008219 547 0.080
cell migration GO:0016477 306 0.078
embryonic morphogenesis GO:0048598 152 0.078
lipid storage GO:0019915 565 0.078
nematode male tail tip morphogenesis GO:0045138 77 0.076
multi organism behavior GO:0051705 389 0.076
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.072
transcription from rna polymerase ii promoter GO:0006366 149 0.072
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.071
head development GO:0060322 1 0.071
positive regulation of epithelial cell proliferation GO:0050679 1 0.070
chemotaxis GO:0006935 120 0.070
oviposition GO:0018991 364 0.069
positive regulation of cell projection organization GO:0031346 4 0.068
positive regulation of biosynthetic process GO:0009891 109 0.068
regulation of primary metabolic process GO:0080090 292 0.068
cell motility GO:0048870 313 0.068
response to endogenous stimulus GO:0009719 33 0.065
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.064
cell proliferation GO:0008283 116 0.064
negative regulation of cell communication GO:0010648 61 0.063
multi multicellular organism process GO:0044706 390 0.061
negative regulation of rna biosynthetic process GO:1902679 53 0.061
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.060
negative regulation of signaling GO:0023057 61 0.056
cell surface receptor signaling pathway GO:0007166 149 0.054
protein modification process GO:0036211 207 0.054
dendrite development GO:0016358 42 0.054
digestive system development GO:0055123 122 0.053
gamete generation GO:0007276 461 0.052
negative regulation of signal transduction GO:0009968 60 0.052
sexual reproduction GO:0019953 546 0.050
cellular protein metabolic process GO:0044267 279 0.049
organic substance catabolic process GO:1901575 294 0.049
defense response GO:0006952 296 0.048
negative regulation of cellular biosynthetic process GO:0031327 65 0.048
endocytosis GO:0006897 819 0.047
positive regulation of nematode larval development GO:0061063 54 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.047
regulation of response to stimulus GO:0048583 243 0.046
single organism behavior GO:0044708 83 0.046
macromolecular complex assembly GO:0065003 193 0.046
dauer larval development GO:0040024 92 0.045
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.044
response to biotic stimulus GO:0009607 101 0.044
macromolecule modification GO:0043412 218 0.044
lipid metabolic process GO:0006629 77 0.044
embryonic body morphogenesis GO:0010172 49 0.044
neurological system process GO:0050877 53 0.043
cellular response to growth factor stimulus GO:0071363 18 0.043
response to bacterium GO:0009617 86 0.042
regulation of neuron differentiation GO:0045664 40 0.042
cell division GO:0051301 262 0.042
single organism transport GO:0044765 447 0.042
positive regulation of neuron projection development GO:0010976 4 0.041
mesodermal cell differentiation GO:0048333 15 0.040
bmp signaling pathway GO:0030509 3 0.040
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.040
regulation of cell differentiation GO:0045595 81 0.040
positive regulation of vulval development GO:0040026 52 0.040
macromolecular complex subunit organization GO:0043933 320 0.039
positive regulation of neurogenesis GO:0050769 4 0.038
adult behavior GO:0030534 3 0.038
female gamete generation GO:0007292 254 0.038
anatomical structure formation involved in morphogenesis GO:0048646 250 0.037
regulation of cell development GO:0060284 49 0.035
male anatomical structure morphogenesis GO:0090598 78 0.035
phagocytosis GO:0006909 115 0.035
oogenesis GO:0048477 229 0.035
inductive cell migration GO:0040039 145 0.034
regulation of cellular protein metabolic process GO:0032268 75 0.034
phosphorus metabolic process GO:0006793 232 0.033
positive regulation of neuron differentiation GO:0045666 4 0.033
cellular response to stress GO:0033554 162 0.033
regulation of cell communication GO:0010646 176 0.033
small molecule metabolic process GO:0044281 186 0.032
cellular localization GO:0051641 360 0.032
localization of cell GO:0051674 313 0.032
negative regulation of bmp signaling pathway GO:0030514 1 0.032
embryonic pattern specification GO:0009880 21 0.031
male sex differentiation GO:0046661 86 0.031
regulation of cell fate commitment GO:0010453 22 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.031
organelle fission GO:0048285 363 0.029
organic acid metabolic process GO:0006082 47 0.029
cellular response to transforming growth factor beta stimulus GO:0071560 13 0.029
phagocytosis engulfment GO:0006911 98 0.029
cuticle development GO:0042335 100 0.029
digestive tract development GO:0048565 122 0.028
cell cycle GO:0007049 526 0.028
digestive tract morphogenesis GO:0048546 76 0.027
regulation of cellular component organization GO:0051128 248 0.026
regulation of nervous system development GO:0051960 41 0.026
negative regulation of rna metabolic process GO:0051253 53 0.025
cellular component assembly GO:0022607 293 0.025
response to oxygen containing compound GO:1901700 44 0.025
defense response to bacterium GO:0042742 86 0.025
establishment of localization in cell GO:0051649 318 0.024
membrane organization GO:0061024 135 0.024
organic substance transport GO:0071702 113 0.024
response to transforming growth factor beta GO:0071559 13 0.024
tube morphogenesis GO:0035239 79 0.023
sensory organ morphogenesis GO:0090596 2 0.023
protein catabolic process GO:0030163 162 0.023
apoptotic cell clearance GO:0043277 111 0.023
response to mechanical stimulus GO:0009612 28 0.022
epithelium development GO:0060429 68 0.022
regulation of cell proliferation GO:0042127 105 0.022
negative regulation of nucleic acid templated transcription GO:1903507 53 0.021
regulation of behavior GO:0050795 97 0.021
single organism organelle organization GO:1902589 501 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.021
positive regulation of stem cell differentiation GO:2000738 1 0.020
detection of external stimulus GO:0009581 4 0.020
epithelial tube morphogenesis GO:0060562 1 0.020
secretion by cell GO:0032940 138 0.020
secretion GO:0046903 147 0.020
oxoacid metabolic process GO:0043436 47 0.020
cell cycle process GO:0022402 482 0.020
epithelial cell proliferation GO:0050673 1 0.020
establishment of localization GO:0051234 1171 0.020
macromolecule catabolic process GO:0009057 202 0.020
neuromuscular junction development GO:0007528 2 0.020
catabolic process GO:0009056 318 0.020
defense response to other organism GO:0098542 100 0.019
cellular catabolic process GO:0044248 199 0.019
regionalization GO:0003002 31 0.019
cellular component biogenesis GO:0044085 297 0.019
regulation of cell fate specification GO:0042659 22 0.019
phosphorylation GO:0016310 116 0.019
protein localization GO:0008104 205 0.019
protein complex subunit organization GO:0071822 280 0.019
mitotic cell cycle process GO:1903047 194 0.018
meiotic cell cycle GO:0051321 335 0.018
response to wounding GO:0009611 4 0.018
cellular macromolecular complex assembly GO:0034622 184 0.018
canonical wnt signaling pathway GO:0060070 3 0.018
cellular response to abiotic stimulus GO:0071214 4 0.018
response to abiotic stimulus GO:0009628 152 0.017
long term memory GO:0007616 2 0.017
regulation of nucleocytoplasmic transport GO:0046822 3 0.017
regulation of cell division GO:0051302 142 0.017
cellular response to oxygen containing compound GO:1901701 21 0.017
phosphate containing compound metabolic process GO:0006796 232 0.017
regeneration GO:0031099 4 0.016
membrane invagination GO:0010324 98 0.016
organ morphogenesis GO:0009887 67 0.016
regulation of locomotion GO:0040012 161 0.016
single organism membrane organization GO:0044802 35 0.016
neuron recognition GO:0008038 83 0.015
carbohydrate metabolic process GO:0005975 34 0.015
regulation of reproductive process GO:2000241 66 0.015
axonal fasciculation GO:0007413 79 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.015
adult locomotory behavior GO:0008344 1 0.015
cellular lipid metabolic process GO:0044255 40 0.015
regulation of cytoplasmic transport GO:1903649 3 0.015
establishment of synaptic vesicle localization GO:0097480 21 0.015
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 2 0.015
positive regulation of cell communication GO:0010647 69 0.015
regulation of epithelial cell proliferation GO:0050678 1 0.014
somatic stem cell division GO:0048103 9 0.014
regulation of anatomical structure morphogenesis GO:0022603 51 0.014
carboxylic acid metabolic process GO:0019752 34 0.014
system process GO:0003008 136 0.014
striated muscle cell development GO:0055002 157 0.014
regulation of multi organism process GO:0043900 69 0.014
muscle cell differentiation GO:0042692 171 0.014
engulfment of apoptotic cell GO:0043652 94 0.014
meiotic nuclear division GO:0007126 300 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
positive regulation of chromosome organization GO:2001252 2 0.013
regulation of development heterochronic GO:0040034 18 0.013
establishment of cell polarity GO:0030010 46 0.013
regulation of protein import into nucleus GO:0042306 3 0.013
positive regulation of post embryonic development GO:0048582 54 0.013
regulation of system process GO:0044057 27 0.013
regulation of hormone secretion GO:0046883 2 0.013
cell type specific apoptotic process GO:0097285 4 0.013
regulation of meiosis GO:0040020 94 0.013
regulation of organelle organization GO:0033043 164 0.012
regulation of cellular catabolic process GO:0031329 51 0.012
cell recognition GO:0008037 85 0.012
chromosome segregation GO:0007059 180 0.012
myosin filament organization GO:0031033 138 0.012
myosin filament assembly GO:0031034 138 0.011
regulation of protein targeting GO:1903533 3 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
chemical homeostasis GO:0048878 29 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
regulation of phosphate metabolic process GO:0019220 81 0.011
cellular amine metabolic process GO:0044106 15 0.011
regulation of organ morphogenesis GO:2000027 4 0.011
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.011
regulation of lipid metabolic process GO:0019216 4 0.011
detection of abiotic stimulus GO:0009582 4 0.011
proximal distal pattern formation GO:0009954 6 0.011
negative regulation of neuron differentiation GO:0045665 4 0.011
muscle structure development GO:0061061 191 0.011
cell maturation GO:0048469 26 0.011
protein phosphorylation GO:0006468 85 0.011
immune response GO:0006955 192 0.010
cellular amino acid metabolic process GO:0006520 15 0.010
organism emergence from protective structure GO:0071684 48 0.010
carbohydrate derivative metabolic process GO:1901135 141 0.010
mesoderm morphogenesis GO:0048332 24 0.010

peb-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.047
cancer DOID:162 0 0.047
organ system cancer DOID:0050686 0 0.047
gastrointestinal system cancer DOID:3119 0 0.045
disease of anatomical entity DOID:7 0 0.025
musculoskeletal system disease DOID:17 0 0.019
large intestine cancer DOID:5672 0 0.017
intestinal cancer DOID:10155 0 0.017