Caenorhabditis elegans

8 known processes

best-8 (CELE_C37A5.1)

Protein BEST-8

best-8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism reproductive process GO:0044702 1196 0.132
embryo development ending in birth or egg hatching GO:0009792 2992 0.106
locomotion GO:0040011 1634 0.097
Worm
multi organism reproductive process GO:0044703 867 0.091
single organism organelle organization GO:1902589 501 0.090
post embryonic development GO:0009791 2152 0.088
developmental process involved in reproduction GO:0003006 1165 0.086
vesicle mediated transport GO:0016192 852 0.081
oviposition GO:0018991 364 0.079
reproductive structure development GO:0048608 850 0.079
sex differentiation GO:0007548 909 0.078
reproductive behavior GO:0019098 387 0.074
macromolecule localization GO:0033036 771 0.072
embryo development GO:0009790 3052 0.070
transport GO:0006810 1093 0.068
multicellular organismal reproductive process GO:0048609 815 0.065
gonad development GO:0008406 840 0.063
multi organism reproductive behavior GO:0044705 387 0.063
endocytosis GO:0006897 819 0.060
maintenance of location GO:0051235 580 0.059
lipid storage GO:0019915 565 0.059
multicellular organism reproduction GO:0032504 819 0.056
development of primary sexual characteristics GO:0045137 840 0.056
body morphogenesis GO:0010171 620 0.053
genitalia development GO:0048806 741 0.052
multicellular organismal reproductive behavior GO:0033057 384 0.051
regulation of biological quality GO:0065008 741 0.050
lipid localization GO:0010876 573 0.050
organ development GO:0048513 1102 0.050
hermaphrodite genitalia development GO:0040035 734 0.050
multi multicellular organism process GO:0044706 390 0.048
reproductive system development GO:0061458 850 0.047
multi organism behavior GO:0051705 389 0.046
cytoskeleton organization GO:0007010 339 0.046
growth GO:0040007 562 0.046
Worm
establishment of localization GO:0051234 1171 0.045
multicellular organism growth GO:0035264 385 0.044
Worm
regulation of developmental growth GO:0048638 389 0.044
Worm
single organism localization GO:1902578 518 0.042
gamete generation GO:0007276 461 0.042
cell development GO:0048468 696 0.041
organelle organization GO:0006996 783 0.041
localization of cell GO:0051674 313 0.041
cell cycle process GO:0022402 482 0.040
regulation of developmental process GO:0050793 684 0.040
Worm
protein complex subunit organization GO:0071822 280 0.040
positive regulation of multicellular organismal process GO:0051240 417 0.040
Worm
regulation of multicellular organismal process GO:0051239 726 0.039
Worm
receptor mediated endocytosis GO:0006898 715 0.038
developmental growth GO:0048589 412 0.038
Worm
cell cycle GO:0007049 526 0.036
macromolecular complex subunit organization GO:0043933 320 0.035
sexual reproduction GO:0019953 546 0.034
programmed cell death GO:0012501 500 0.034
actin cytoskeleton organization GO:0030036 184 0.033
determination of adult lifespan GO:0008340 812 0.033
cellular component movement GO:0006928 388 0.033
cellular component assembly involved in morphogenesis GO:0010927 183 0.033
phosphate containing compound metabolic process GO:0006796 232 0.032
cellular component morphogenesis GO:0032989 318 0.032
phosphorus metabolic process GO:0006793 232 0.031
regulation of metabolic process GO:0019222 478 0.031
death GO:0016265 547 0.031
regulation of multicellular organism growth GO:0040014 373 0.030
Worm
cell motility GO:0048870 313 0.030
protein complex assembly GO:0006461 186 0.030
inductive cell migration GO:0040039 145 0.030
protein metabolic process GO:0019538 422 0.028
muscle structure development GO:0061061 191 0.028
regulation of growth GO:0040008 409 0.028
Worm
multicellular organismal aging GO:0010259 812 0.028
positive regulation of multicellular organism growth GO:0040018 352 0.027
Worm
positive regulation of developmental process GO:0051094 408 0.027
Worm
actomyosin structure organization GO:0031032 154 0.027
meiotic cell cycle GO:0051321 335 0.026
aging GO:0007568 812 0.026
myofibril assembly GO:0030239 154 0.025
striated muscle cell development GO:0055002 157 0.025
cell migration GO:0016477 306 0.025
behavior GO:0007610 527 0.024
cellular component biogenesis GO:0044085 297 0.024
macromolecular complex assembly GO:0065003 193 0.023
regulation of response to stimulus GO:0048583 243 0.023
single organism transport GO:0044765 447 0.022
catabolic process GO:0009056 318 0.022
organelle fission GO:0048285 363 0.022
actin filament based process GO:0030029 191 0.022
macromolecule modification GO:0043412 218 0.022
cell death GO:0008219 547 0.022
regulation of cellular metabolic process GO:0031323 305 0.022
nucleobase containing compound metabolic process GO:0006139 406 0.022
regulation of organelle organization GO:0033043 164 0.022
positive regulation of growth GO:0045927 369 0.022
Worm
positive regulation of developmental growth GO:0048639 354 0.021
Worm
cellular macromolecular complex assembly GO:0034622 184 0.021
regulation of cell cycle GO:0051726 194 0.021
striated muscle cell differentiation GO:0051146 158 0.021
regulation of response to wounding GO:1903034 1 0.020
regulation of locomotion GO:0040012 161 0.020
organelle assembly GO:0070925 214 0.020
protein complex biogenesis GO:0070271 186 0.020
cellular component assembly GO:0022607 293 0.020
cellular protein complex assembly GO:0043623 178 0.020
negative regulation of biological process GO:0048519 567 0.020
organonitrogen compound metabolic process GO:1901564 151 0.019
cellular protein modification process GO:0006464 207 0.018
response to topologically incorrect protein GO:0035966 82 0.018
cellular localization GO:0051641 360 0.018
protein localization GO:0008104 205 0.018
cellular protein metabolic process GO:0044267 279 0.018
biosynthetic process GO:0009058 323 0.018
signaling GO:0023052 401 0.018
regulation of macromolecule metabolic process GO:0060255 421 0.018
cellular response to stress GO:0033554 162 0.017
regulation of post embryonic development GO:0048580 260 0.017
apoptotic process GO:0006915 478 0.017
response to wounding GO:0009611 4 0.017
neurogenesis GO:0022008 236 0.017
molting cycle GO:0042303 281 0.017
nematode male tail tip morphogenesis GO:0045138 77 0.017
regulation of epithelial cell proliferation GO:0050678 1 0.017
meiotic nuclear division GO:0007126 300 0.017
protein oligomerization GO:0051259 4 0.017
negative regulation of developmental process GO:0051093 227 0.017
signal transduction GO:0007165 317 0.017
cell surface receptor signaling pathway GO:0007166 149 0.017
single organism signaling GO:0044700 401 0.016
secretion GO:0046903 147 0.016
positive regulation of cellular process GO:0048522 332 0.016
regulation of cellular component organization GO:0051128 248 0.016
negative regulation of multicellular organismal process GO:0051241 236 0.016
organic substance catabolic process GO:1901575 294 0.016
gene silencing by rna GO:0031047 143 0.016
muscle cell differentiation GO:0042692 171 0.016
regeneration GO:0031099 4 0.016
establishment of localization in cell GO:0051649 318 0.015
phagocytosis engulfment GO:0006911 98 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.015
epithelial cell proliferation GO:0050673 1 0.015
myosin filament assembly GO:0031034 138 0.014
regulation of nuclear division GO:0051783 115 0.014
anatomical structure formation involved in morphogenesis GO:0048646 250 0.014
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.014
muscle cell development GO:0055001 158 0.014
organic substance biosynthetic process GO:1901576 323 0.014
sensory organ morphogenesis GO:0090596 2 0.014
posttranscriptional regulation of gene expression GO:0010608 166 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
regulation of nematode larval development GO:0061062 260 0.014
acetylcholine metabolic process GO:0008291 4 0.014
cell division GO:0051301 262 0.014
small molecule metabolic process GO:0044281 186 0.014
positive regulation of neurogenesis GO:0050769 4 0.014
myosin filament organization GO:0031033 138 0.014
cell fate commitment GO:0045165 139 0.014
chromosome segregation GO:0007059 180 0.014
head development GO:0060322 1 0.014
regulation of meiosis GO:0040020 94 0.014
cellular biosynthetic process GO:0044249 315 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.013
cellular amine metabolic process GO:0044106 15 0.013
posttranscriptional gene silencing GO:0016441 143 0.013
acetylcholine catabolic process GO:0006581 4 0.013
regulation of primary metabolic process GO:0080090 292 0.013
protein modification process GO:0036211 207 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
protein catabolic process GO:0030163 162 0.013
negative regulation of cellular process GO:0048523 239 0.013
gene silencing GO:0016458 143 0.013
regulation of cell proliferation GO:0042127 105 0.013
small gtpase mediated signal transduction GO:0007264 32 0.013
germ cell development GO:0007281 351 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
amine metabolic process GO:0009308 15 0.012
engulfment of apoptotic cell GO:0043652 94 0.012
regulation of stem cell differentiation GO:2000736 1 0.012
response to external stimulus GO:0009605 289 0.012
regulation of meiotic cell cycle GO:0051445 136 0.012
cellular response to topologically incorrect protein GO:0035967 76 0.012
oogenesis GO:0048477 229 0.012
ion transmembrane transport GO:0034220 91 0.012
organelle localization GO:0051640 127 0.012
organophosphate metabolic process GO:0019637 125 0.012
nucleic acid metabolic process GO:0090304 299 0.012
epithelial tube morphogenesis GO:0060562 1 0.012
transmembrane transport GO:0055085 110 0.011
female gamete generation GO:0007292 254 0.011
macromolecule catabolic process GO:0009057 202 0.011
apoptotic cell clearance GO:0043277 111 0.011
gene expression GO:0010467 412 0.011
regulation of cell division GO:0051302 142 0.011
mitotic cell cycle process GO:1903047 194 0.011
defense response GO:0006952 296 0.011
response to bacterium GO:0009617 86 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
cell adhesion GO:0007155 21 0.011
cell proliferation GO:0008283 116 0.011
regulation of gene expression epigenetic GO:0040029 163 0.011
generation of neurons GO:0048699 235 0.011
cell matrix adhesion GO:0007160 1 0.011
skeletal muscle organ development GO:0060538 3 0.011
regulation of localization GO:0032879 194 0.011
defense response to other organism GO:0098542 100 0.011
negative regulation of post embryonic development GO:0048581 208 0.010
cellular macromolecule biosynthetic process GO:0034645 247 0.010
regulation of organ morphogenesis GO:2000027 4 0.010
negative regulation of gene expression GO:0010629 217 0.010
adult behavior GO:0030534 3 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.010
ras protein signal transduction GO:0007265 31 0.010
male anatomical structure morphogenesis GO:0090598 78 0.010
cell substrate adhesion GO:0031589 1 0.010
organic substance transport GO:0071702 113 0.010
rna interference GO:0016246 137 0.010
negative regulation of ion transmembrane transport GO:0034766 3 0.010
regulation of gene expression GO:0010468 366 0.010

best-8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014