Caenorhabditis elegans

29 known processes

pole-2 (CELE_F08B4.5)

Protein POLE-2

pole-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.850
embryo development ending in birth or egg hatching GO:0009792 2992 0.581
negative regulation of vulval development GO:0040027 206 0.526
hermaphrodite genitalia development GO:0040035 734 0.395
post embryonic development GO:0009791 2152 0.393
locomotion GO:0040011 1634 0.361
organ development GO:0048513 1102 0.350
genitalia development GO:0048806 741 0.350
oviposition GO:0018991 364 0.307
cell cycle process GO:0022402 482 0.307
sex differentiation GO:0007548 909 0.301
vulval development GO:0040025 333 0.286
meiotic nuclear division GO:0007126 300 0.281
reproductive structure development GO:0048608 850 0.245
body morphogenesis GO:0010171 620 0.244
development of primary sexual characteristics GO:0045137 840 0.227
multicellular organism reproduction GO:0032504 819 0.225
behavior GO:0007610 527 0.225
multicellular organismal reproductive behavior GO:0033057 384 0.208
regulation of vulval development GO:0040028 248 0.207
negative regulation of nematode larval development GO:0061064 208 0.201
organelle fission GO:0048285 363 0.195
multicellular organismal reproductive process GO:0048609 815 0.195
reproductive system development GO:0061458 850 0.193
cellular component movement GO:0006928 388 0.185
response to chemical GO:0042221 356 0.167
multi organism reproductive behavior GO:0044705 387 0.157
gonad development GO:0008406 840 0.157
multi organism behavior GO:0051705 389 0.143
cell cycle GO:0007049 526 0.140
meiotic cell cycle GO:0051321 335 0.136
multi organism reproductive process GO:0044703 867 0.134
neuron projection guidance GO:0097485 82 0.133
gamete generation GO:0007276 461 0.131
regulation of cell cycle GO:0051726 194 0.129
catabolic process GO:0009056 318 0.124
developmental process involved in reproduction GO:0003006 1165 0.122
negative regulation of biological process GO:0048519 567 0.120
multi multicellular organism process GO:0044706 390 0.118
cell motility GO:0048870 313 0.114
cell migration GO:0016477 306 0.109
cell division GO:0051301 262 0.105
regulation of multicellular organismal process GO:0051239 726 0.101
cellular protein metabolic process GO:0044267 279 0.100
reproductive behavior GO:0019098 387 0.099
organic substance catabolic process GO:1901575 294 0.098
regulation of meiotic cell cycle GO:0051445 136 0.096
post embryonic organ development GO:0048569 336 0.096
regulation of gene expression GO:0010468 366 0.092
regulation of organelle organization GO:0033043 164 0.092
regulation of nematode larval development GO:0061062 260 0.088
nervous system development GO:0007399 253 0.086
organelle organization GO:0006996 783 0.084
germ cell development GO:0007281 351 0.084
chromosome segregation GO:0007059 180 0.081
single organism signaling GO:0044700 401 0.079
regulation of multicellular organismal development GO:2000026 317 0.076
regulation of meiosis GO:0040020 94 0.074
regulation of biological quality GO:0065008 741 0.073
cell projection organization GO:0030030 231 0.073
negative regulation of post embryonic development GO:0048581 208 0.073
cell development GO:0048468 696 0.070
growth GO:0040007 562 0.068
oogenesis GO:0048477 229 0.068
regulation of developmental process GO:0050793 684 0.067
meiotic cell cycle process GO:1903046 170 0.064
axonogenesis GO:0007409 102 0.064
regulation of growth GO:0040008 409 0.062
organic substance biosynthetic process GO:1901576 323 0.061
protein metabolic process GO:0019538 422 0.061
determination of adult lifespan GO:0008340 812 0.060
regulation of cellular metabolic process GO:0031323 305 0.058
single organism reproductive process GO:0044702 1196 0.058
regulation of metabolic process GO:0019222 478 0.058
sexual reproduction GO:0019953 546 0.056
cellular catabolic process GO:0044248 199 0.054
negative regulation of developmental process GO:0051093 227 0.053
regulation of nuclear division GO:0051783 115 0.052
mrna catabolic process GO:0006402 16 0.052
programmed cell death GO:0012501 500 0.051
cellular component morphogenesis GO:0032989 318 0.051
macromolecule biosynthetic process GO:0009059 250 0.050
neurogenesis GO:0022008 236 0.050
generation of neurons GO:0048699 235 0.049
negative regulation of cellular process GO:0048523 239 0.049
negative regulation of macromolecule metabolic process GO:0010605 229 0.049
cellular nitrogen compound catabolic process GO:0044270 119 0.049
biosynthetic process GO:0009058 323 0.048
maintenance of location GO:0051235 580 0.047
multicellular organismal aging GO:0010259 812 0.047
meiotic chromosome segregation GO:0045132 139 0.047
cellular biosynthetic process GO:0044249 315 0.047
macromolecule modification GO:0043412 218 0.046
neuron projection development GO:0031175 187 0.046
aromatic compound catabolic process GO:0019439 116 0.045
receptor mediated endocytosis GO:0006898 715 0.045
lipid storage GO:0019915 565 0.044
vesicle mediated transport GO:0016192 852 0.044
regulation of gene expression epigenetic GO:0040029 163 0.043
regulation of macromolecule metabolic process GO:0060255 421 0.043
negative regulation of multicellular organismal process GO:0051241 236 0.041
axon guidance GO:0007411 82 0.040
lipid localization GO:0010876 573 0.040
localization of cell GO:0051674 313 0.039
organic cyclic compound catabolic process GO:1901361 119 0.037
regulation of cellular component organization GO:0051128 248 0.037
regulation of cell division GO:0051302 142 0.037
macromolecule localization GO:0033036 771 0.037
neuron projection morphogenesis GO:0048812 114 0.035
female gamete generation GO:0007292 254 0.035
macromolecule catabolic process GO:0009057 202 0.034
signaling GO:0023052 401 0.034
protein modification process GO:0036211 207 0.034
regulation of cell cycle process GO:0010564 145 0.034
positive regulation of developmental process GO:0051094 408 0.034
endocytosis GO:0006897 819 0.034
developmental growth GO:0048589 412 0.033
gene expression GO:0010467 412 0.032
nucleobase containing compound catabolic process GO:0034655 114 0.032
phosphate containing compound metabolic process GO:0006796 232 0.032
cellular localization GO:0051641 360 0.031
heterocycle catabolic process GO:0046700 119 0.031
negative regulation of gene expression GO:0010629 217 0.031
small molecule metabolic process GO:0044281 186 0.031
organelle assembly GO:0070925 214 0.031
rna metabolic process GO:0016070 228 0.030
posttranscriptional gene silencing GO:0016441 143 0.030
cellular component biogenesis GO:0044085 297 0.030
neuron development GO:0048666 199 0.030
regulation of post embryonic development GO:0048580 260 0.029
regulation of developmental growth GO:0048638 389 0.029
cell part morphogenesis GO:0032990 152 0.028
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.028
chemotaxis GO:0006935 120 0.028
regulation of rna biosynthetic process GO:2001141 165 0.027
cellular protein modification process GO:0006464 207 0.027
multicellular organism growth GO:0035264 385 0.027
gene silencing by rna GO:0031047 143 0.027
head development GO:0060322 1 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.025
regulation of cell communication GO:0010646 176 0.025
axon development GO:0061564 163 0.025
nucleobase containing compound metabolic process GO:0006139 406 0.025
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 9 0.025
aging GO:0007568 812 0.025
positive regulation of vulval development GO:0040026 52 0.024
mitotic cell cycle process GO:1903047 194 0.024
rna biosynthetic process GO:0032774 169 0.023
positive regulation of multicellular organism growth GO:0040018 352 0.023
positive regulation of nematode larval development GO:0061063 54 0.023
single organism organelle organization GO:1902589 501 0.022
negative regulation of metabolic process GO:0009892 240 0.022
cellular component assembly GO:0022607 293 0.022
positive regulation of developmental growth GO:0048639 354 0.022
neuron differentiation GO:0030182 217 0.021
rrna processing GO:0006364 3 0.021
carbohydrate derivative metabolic process GO:1901135 141 0.021
posttranscriptional regulation of gene expression GO:0010608 166 0.021
cellular response to organic substance GO:0071310 119 0.020
actin filament based process GO:0030029 191 0.020
regulation of primary metabolic process GO:0080090 292 0.020
regulation of multicellular organism growth GO:0040014 373 0.020
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
signal transduction GO:0007165 317 0.019
positive regulation of multicellular organismal process GO:0051240 417 0.019
molting cycle GO:0042303 281 0.018
gene silencing GO:0016458 143 0.018
nucleic acid metabolic process GO:0090304 299 0.018
regulation of response to stimulus GO:0048583 243 0.018
cell death GO:0008219 547 0.018
oocyte construction GO:0007308 2 0.018
death GO:0016265 547 0.017
tissue development GO:0009888 112 0.017
posttranscriptional gene silencing by rna GO:0035194 143 0.017
cell projection morphogenesis GO:0048858 148 0.017
single organism localization GO:1902578 518 0.017
positive regulation of growth GO:0045927 369 0.016
secretion GO:0046903 147 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.016
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.016
sister chromatid segregation GO:0000819 46 0.015
cell proliferation GO:0008283 116 0.015
cellular macromolecule biosynthetic process GO:0034645 247 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.015
mitotic g2 m transition checkpoint GO:0044818 1 0.014
organelle localization GO:0051640 127 0.014
muscle cell development GO:0055001 158 0.014
cellular macromolecule catabolic process GO:0044265 73 0.014
single organism catabolic process GO:0044712 129 0.014
pattern specification process GO:0007389 59 0.014
rna catabolic process GO:0006401 21 0.014
organonitrogen compound metabolic process GO:1901564 151 0.014
macromolecular complex subunit organization GO:0043933 320 0.014
striated muscle cell development GO:0055002 157 0.014
organophosphate metabolic process GO:0019637 125 0.013
positive regulation of cellular metabolic process GO:0031325 178 0.013
taxis GO:0042330 128 0.013
muscle structure development GO:0061061 191 0.013
regulation of signaling GO:0023051 172 0.013
protein complex subunit organization GO:0071822 280 0.013
cell recognition GO:0008037 85 0.013
polarity specification of proximal distal axis GO:0010085 6 0.013
rna interference GO:0016246 137 0.013
aromatic compound biosynthetic process GO:0019438 192 0.013
neuron recognition GO:0008038 83 0.012
actomyosin structure organization GO:0031032 154 0.012
lipid metabolic process GO:0006629 77 0.012
cytoskeleton organization GO:0007010 339 0.012
response to external stimulus GO:0009605 289 0.012
regulation of biosynthetic process GO:0009889 189 0.012
cytokinesis GO:0000910 80 0.012
apoptotic process GO:0006915 478 0.012
glycosyl compound catabolic process GO:1901658 79 0.012
axonal fasciculation GO:0007413 79 0.012
myosin filament organization GO:0031033 138 0.011
neuromuscular junction development GO:0007528 2 0.011
epithelial tube morphogenesis GO:0060562 1 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
positive regulation of post embryonic development GO:0048582 54 0.011
regulation of rna metabolic process GO:0051252 173 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.011
macromolecular complex assembly GO:0065003 193 0.011
regulation of cell proliferation GO:0042127 105 0.011
protein complex biogenesis GO:0070271 186 0.011
nucleobase containing compound biosynthetic process GO:0034654 184 0.011
negative regulation of cellular component organization GO:0051129 33 0.010
protein oligomerization GO:0051259 4 0.010
collagen and cuticulin based cuticle development GO:0040002 99 0.010
regulation of locomotion GO:0040012 161 0.010
microtubule based movement GO:0007018 33 0.010
muscle cell differentiation GO:0042692 171 0.010

pole-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027