Caenorhabditis elegans

80 known processes

vha-12 (CELE_F20B6.2)

Protein VHA-12

vha-12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.597
embryo development GO:0009790 3052 0.585
establishment of localization GO:0051234 1171 0.538
Mouse Fly
multicellular organism reproduction GO:0032504 819 0.439
post embryonic development GO:0009791 2152 0.361
sexual reproduction GO:0019953 546 0.308
vesicle mediated transport GO:0016192 852 0.268
aging GO:0007568 812 0.267
Worm
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.234
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.217
transport GO:0006810 1093 0.212
Mouse Fly
membrane organization GO:0061024 135 0.207
developmental process involved in reproduction GO:0003006 1165 0.178
multicellular organismal reproductive process GO:0048609 815 0.172
determination of adult lifespan GO:0008340 812 0.162
Worm
single organism localization GO:1902578 518 0.159
Mouse Fly
single organism reproductive process GO:0044702 1196 0.156
endocytosis GO:0006897 819 0.152
localization of cell GO:0051674 313 0.127
organ development GO:0048513 1102 0.127
multi organism reproductive process GO:0044703 867 0.125
receptor mediated endocytosis GO:0006898 715 0.125
body morphogenesis GO:0010171 620 0.117
cellular localization GO:0051641 360 0.108
macromolecule localization GO:0033036 771 0.108
Worm
cellular response to chemical stimulus GO:0070887 129 0.106
fatty acid metabolic process GO:0006631 16 0.105
regulation of biological quality GO:0065008 741 0.103
signaling GO:0023052 401 0.096
programmed cell death GO:0012501 500 0.093
regulation of signaling GO:0023051 172 0.093
cell development GO:0048468 696 0.093
germ cell development GO:0007281 351 0.090
female gamete generation GO:0007292 254 0.088
catabolic process GO:0009056 318 0.088
Fly
signal transduction GO:0007165 317 0.087
cell migration GO:0016477 306 0.082
head development GO:0060322 1 0.077
multicellular organismal reproductive behavior GO:0033057 384 0.076
multicellular organismal aging GO:0010259 812 0.075
Worm
locomotion GO:0040011 1634 0.075
muscle organ morphogenesis GO:0048644 4 0.071
oogenesis GO:0048477 229 0.070
maintenance of location GO:0051235 580 0.067
Worm
cellular component movement GO:0006928 388 0.066
lipid storage GO:0019915 565 0.065
Worm
lipid localization GO:0010876 573 0.065
Worm
molting cycle GO:0042303 281 0.065
digestive system development GO:0055123 122 0.064
multicellular organism growth GO:0035264 385 0.058
tissue development GO:0009888 112 0.057
apoptotic process GO:0006915 478 0.057
regulation of developmental growth GO:0048638 389 0.056
organonitrogen compound metabolic process GO:1901564 151 0.056
Fly
mitotic nuclear envelope reassembly GO:0007084 3 0.055
cellular component assembly GO:0022607 293 0.055
regulation of developmental process GO:0050793 684 0.053
organelle localization GO:0051640 127 0.050
regulation of multicellular organismal process GO:0051239 726 0.049
cellular response to organic substance GO:0071310 119 0.049
single organism signaling GO:0044700 401 0.048
cellular component assembly involved in morphogenesis GO:0010927 183 0.047
endoplasmic reticulum unfolded protein response GO:0030968 66 0.047
reproductive system development GO:0061458 850 0.047
reproductive behavior GO:0019098 387 0.046
regulation of locomotion GO:0040012 161 0.045
cell motility GO:0048870 313 0.045
single organism membrane organization GO:0044802 35 0.043
sex differentiation GO:0007548 909 0.043
regulation of macromolecule metabolic process GO:0060255 421 0.043
cellular response to stress GO:0033554 162 0.039
regulation of multicellular organism growth GO:0040014 373 0.039
gamete generation GO:0007276 461 0.038
secretion GO:0046903 147 0.038
cellular component morphogenesis GO:0032989 318 0.037
tube morphogenesis GO:0035239 79 0.037
organelle fission GO:0048285 363 0.037
protein metabolic process GO:0019538 422 0.037
developmental growth GO:0048589 412 0.036
cell death GO:0008219 547 0.036
multi organism behavior GO:0051705 389 0.035
oxoacid metabolic process GO:0043436 47 0.035
regulation of growth GO:0040008 409 0.033
lipid metabolic process GO:0006629 77 0.033
response to chemical GO:0042221 356 0.033
protein catabolic process GO:0030163 162 0.032
organ morphogenesis GO:0009887 67 0.032
biosynthetic process GO:0009058 323 0.032
gene expression GO:0010467 412 0.031
positive regulation of developmental process GO:0051094 408 0.031
cellular nitrogen compound biosynthetic process GO:0044271 192 0.031
muscle organ development GO:0007517 26 0.031
positive regulation of developmental growth GO:0048639 354 0.030
behavior GO:0007610 527 0.030
secretion by cell GO:0032940 138 0.030
death GO:0016265 547 0.030
cellular response to topologically incorrect protein GO:0035967 76 0.030
meiotic nuclear division GO:0007126 300 0.029
organic substance catabolic process GO:1901575 294 0.029
Fly
growth GO:0040007 562 0.029
response to organic substance GO:0010033 131 0.028
small molecule metabolic process GO:0044281 186 0.028
Fly
regulation of response to stimulus GO:0048583 243 0.028
embryonic morphogenesis GO:0048598 152 0.027
tube development GO:0035295 126 0.026
cellular biosynthetic process GO:0044249 315 0.026
nuclear pore distribution GO:0031081 2 0.026
regulation of localization GO:0032879 194 0.026
phosphate containing compound metabolic process GO:0006796 232 0.026
Fly
organic substance biosynthetic process GO:1901576 323 0.026
anatomical structure formation involved in morphogenesis GO:0048646 250 0.025
multi organism reproductive behavior GO:0044705 387 0.025
organelle organization GO:0006996 783 0.025
response to wounding GO:0009611 4 0.024
nucleus localization GO:0051647 55 0.024
negative regulation of biological process GO:0048519 567 0.023
establishment or maintenance of cell polarity GO:0007163 63 0.023
establishment of nucleus localization GO:0040023 55 0.023
phosphorus metabolic process GO:0006793 232 0.023
Fly
positive regulation of multicellular organism growth GO:0040018 352 0.023
regulation of metabolic process GO:0019222 478 0.023
inductive cell migration GO:0040039 145 0.023
regulation of gene expression GO:0010468 366 0.023
macromolecule catabolic process GO:0009057 202 0.023
monocarboxylic acid metabolic process GO:0032787 22 0.022
organic acid metabolic process GO:0006082 47 0.022
apoptotic cell clearance GO:0043277 111 0.022
gonad development GO:0008406 840 0.021
reproductive structure development GO:0048608 850 0.021
muscle tissue development GO:0060537 1 0.020
macromolecular complex subunit organization GO:0043933 320 0.020
er nucleus signaling pathway GO:0006984 66 0.020
membrane invagination GO:0010324 98 0.020
multi multicellular organism process GO:0044706 390 0.019
regulation of signal transduction GO:0009966 135 0.019
carboxylic acid metabolic process GO:0019752 34 0.019
striated muscle cell differentiation GO:0051146 158 0.019
protein complex assembly GO:0006461 186 0.019
organic substance transport GO:0071702 113 0.018
establishment of localization in cell GO:0051649 318 0.018
development of primary sexual characteristics GO:0045137 840 0.018
sensory organ morphogenesis GO:0090596 2 0.017
oviposition GO:0018991 364 0.017
transcription dna templated GO:0006351 168 0.017
nuclear migration GO:0007097 54 0.017
response to acid chemical GO:0001101 4 0.017
cellular response to unfolded protein GO:0034620 71 0.017
macromolecular complex assembly GO:0065003 193 0.017
nucleobase containing compound metabolic process GO:0006139 406 0.016
Fly
regulation of apoptotic signaling pathway GO:2001233 1 0.016
regulation of cellular component organization GO:0051128 248 0.016
response to topologically incorrect protein GO:0035966 82 0.016
protein complex biogenesis GO:0070271 186 0.016
regulation of actin filament based process GO:0032970 22 0.016
meiotic cell cycle GO:0051321 335 0.016
regeneration GO:0031099 4 0.016
regulation of gene expression epigenetic GO:0040029 163 0.016
protein complex subunit organization GO:0071822 280 0.016
chromosome segregation GO:0007059 180 0.016
muscle cell development GO:0055001 158 0.015
regulation of cell communication GO:0010646 176 0.015
skeletal muscle thin filament assembly GO:0030240 3 0.015
regulation of vulval development GO:0040028 248 0.015
digestive tract development GO:0048565 122 0.015
engulfment of apoptotic cell GO:0043652 94 0.015
adult behavior GO:0030534 3 0.015
phagocytosis GO:0006909 115 0.015
muscle cell differentiation GO:0042692 171 0.015
gene silencing GO:0016458 143 0.015
cell projection organization GO:0030030 231 0.015
single organism transport GO:0044765 447 0.015
Mouse Fly
phagocytosis engulfment GO:0006911 98 0.014
single organism biosynthetic process GO:0044711 91 0.014
localization within membrane GO:0051668 2 0.014
macromolecule biosynthetic process GO:0009059 250 0.014
posttranscriptional regulation of gene expression GO:0010608 166 0.014
negative regulation of post embryonic development GO:0048581 208 0.014
cellular amine metabolic process GO:0044106 15 0.014
cytoskeleton organization GO:0007010 339 0.014
ovulation GO:0030728 33 0.013
organophosphate metabolic process GO:0019637 125 0.013
Fly
regulation of organelle organization GO:0033043 164 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.013
cellular protein localization GO:0034613 75 0.013
cuticle development GO:0042335 100 0.013
hormone metabolic process GO:0042445 3 0.013
post embryonic organ development GO:0048569 336 0.013
striated muscle cell development GO:0055002 157 0.013
negative regulation of multicellular organismal process GO:0051241 236 0.012
cellular ketone metabolic process GO:0042180 14 0.012
establishment of protein localization to membrane GO:0090150 3 0.012
single organism organelle organization GO:1902589 501 0.012
regulation of transcription dna templated GO:0006355 164 0.012
hermaphrodite genitalia development GO:0040035 734 0.012
carbohydrate derivative metabolic process GO:1901135 141 0.012
Fly
chromatin remodeling GO:0006338 2 0.012
positive regulation of growth GO:0045927 369 0.012
myofibril assembly GO:0030239 154 0.012
genitalia development GO:0048806 741 0.012
negative regulation of dna dependent dna replication GO:2000104 1 0.012
digestive tract morphogenesis GO:0048546 76 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
cellular response to hormone stimulus GO:0032870 14 0.011
regulation of nematode larval development GO:0061062 260 0.011
actomyosin structure organization GO:0031032 154 0.011
vulval development GO:0040025 333 0.011
rna localization GO:0006403 3 0.010
amine metabolic process GO:0009308 15 0.010
posttranscriptional gene silencing GO:0016441 143 0.010
myosin filament organization GO:0031033 138 0.010
collagen and cuticulin based cuticle development GO:0040002 99 0.010
actin cytoskeleton organization GO:0030036 184 0.010
negative regulation of nematode larval development GO:0061064 208 0.010
heterocycle biosynthetic process GO:0018130 187 0.010
positive regulation of multicellular organismal process GO:0051240 417 0.010
aromatic compound biosynthetic process GO:0019438 192 0.010
posttranscriptional gene silencing by rna GO:0035194 143 0.010

vha-12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
disease of metabolism DOID:0014667 0 0.017
muscular disease DOID:0080000 0 0.017
musculoskeletal system disease DOID:17 0 0.017
myopathy DOID:423 0 0.017
muscular dystrophy DOID:9884 0 0.017
emery dreifuss muscular dystrophy DOID:11726 0 0.017
muscle tissue disease DOID:66 0 0.017
congenital muscular dystrophy DOID:0050557 0 0.015
lipodystrophy DOID:811 0 0.014
skin disease DOID:37 0 0.014
integumentary system disease DOID:16 0 0.014
familial partial lipodystrophy DOID:0050440 0 0.014
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cardiovascular system disease DOID:1287 0 0.011