Caenorhabditis elegans

84 known processes

ash-2 (CELE_Y17G7B.2)

Protein ASH-2

ash-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.864
embryo development GO:0009790 3052 0.800
development of primary sexual characteristics GO:0045137 840 0.748
organ development GO:0048513 1102 0.726
reproductive structure development GO:0048608 850 0.648
single organism reproductive process GO:0044702 1196 0.640
post embryonic development GO:0009791 2152 0.628
reproductive system development GO:0061458 850 0.603
hermaphrodite genitalia development GO:0040035 734 0.523
developmental process involved in reproduction GO:0003006 1165 0.478
vulval development GO:0040025 333 0.469
regulation of developmental process GO:0050793 684 0.450
sex differentiation GO:0007548 909 0.445
meiotic cell cycle GO:0051321 335 0.436
genitalia development GO:0048806 741 0.401
gonad development GO:0008406 840 0.353
gamete generation GO:0007276 461 0.283
regulation of vulval development GO:0040028 248 0.270
sexual reproduction GO:0019953 546 0.266
locomotion GO:0040011 1634 0.260
germ cell development GO:0007281 351 0.240
cell division GO:0051301 262 0.230
multicellular organismal reproductive process GO:0048609 815 0.226
oogenesis GO:0048477 229 0.223
single organism organelle organization GO:1902589 501 0.207
meiotic nuclear division GO:0007126 300 0.196
negative regulation of vulval development GO:0040027 206 0.194
cell cycle process GO:0022402 482 0.189
regulation of cellular component organization GO:0051128 248 0.188
nucleobase containing compound metabolic process GO:0006139 406 0.184
Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.180
Mouse Fly
cell cycle GO:0007049 526 0.178
signal transduction GO:0007165 317 0.169
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.163
regulation of cell cycle GO:0051726 194 0.162
nucleic acid metabolic process GO:0090304 299 0.159
Mouse Fly
regulation of organelle organization GO:0033043 164 0.154
establishment of localization GO:0051234 1171 0.150
regulation of metabolic process GO:0019222 478 0.144
Mouse Fly
regulation of nematode larval development GO:0061062 260 0.143
regulation of meiotic cell cycle GO:0051445 136 0.143
post embryonic organ development GO:0048569 336 0.142
vesicle mediated transport GO:0016192 852 0.141
negative regulation of nematode larval development GO:0061064 208 0.141
negative regulation of multicellular organismal process GO:0051241 236 0.138
receptor mediated endocytosis GO:0006898 715 0.136
signaling GO:0023052 401 0.127
multi organism reproductive process GO:0044703 867 0.126
female gamete generation GO:0007292 254 0.122
organelle organization GO:0006996 783 0.121
regulation of multicellular organismal process GO:0051239 726 0.110
protein metabolic process GO:0019538 422 0.109
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.108
Mouse Fly
single organism signaling GO:0044700 401 0.103
regulation of transcription dna templated GO:0006355 164 0.101
Mouse Fly
regulation of primary metabolic process GO:0080090 292 0.097
Mouse Fly
regulation of macromolecule metabolic process GO:0060255 421 0.094
Mouse Fly
phosphate containing compound metabolic process GO:0006796 232 0.093
meiotic cell cycle process GO:1903046 170 0.091
cellular localization GO:0051641 360 0.090
cellular macromolecule biosynthetic process GO:0034645 247 0.089
Mouse Fly
aging GO:0007568 812 0.089
macromolecule localization GO:0033036 771 0.088
head development GO:0060322 1 0.086
multicellular organism reproduction GO:0032504 819 0.086
cellular protein modification process GO:0006464 207 0.086
protein modification process GO:0036211 207 0.082
regulation of biological quality GO:0065008 741 0.081
organelle fission GO:0048285 363 0.079
negative regulation of biological process GO:0048519 567 0.078
biosynthetic process GO:0009058 323 0.078
Mouse Fly
gene expression GO:0010467 412 0.077
Mouse Fly
regulation of cell cycle process GO:0010564 145 0.075
cell development GO:0048468 696 0.074
Fly
transport GO:0006810 1093 0.074
regulation of nitrogen compound metabolic process GO:0051171 222 0.073
Mouse Fly
single organism localization GO:1902578 518 0.072
positive regulation of signaling GO:0023056 66 0.072
endocytosis GO:0006897 819 0.072
multicellular organismal aging GO:0010259 812 0.071
regulation of biosynthetic process GO:0009889 189 0.071
Mouse Fly
regulation of growth GO:0040008 409 0.069
protein localization GO:0008104 205 0.069
chromosome organization GO:0051276 104 0.068
lipid localization GO:0010876 573 0.064
maintenance of location GO:0051235 580 0.064
positive regulation of multicellular organismal process GO:0051240 417 0.063
negative regulation of post embryonic development GO:0048581 208 0.063
positive regulation of nucleoside metabolic process GO:0045979 28 0.063
cellular macromolecule localization GO:0070727 75 0.062
regulation of post embryonic development GO:0048580 260 0.062
positive regulation of epithelial cell proliferation GO:0050679 1 0.061
regulation of cellular metabolic process GO:0031323 305 0.059
Mouse Fly
cytoskeleton organization GO:0007010 339 0.059
lipid storage GO:0019915 565 0.059
determination of adult lifespan GO:0008340 812 0.058
cell proliferation GO:0008283 116 0.058
regulation of cell division GO:0051302 142 0.058
multicellular organism growth GO:0035264 385 0.057
cellular biosynthetic process GO:0044249 315 0.057
Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.057
Mouse Fly
positive regulation of vulval development GO:0040026 52 0.056
positive regulation of ras protein signal transduction GO:0046579 7 0.053
regulation of multicellular organismal development GO:2000026 317 0.053
cell death GO:0008219 547 0.052
positive regulation of gtpase activity GO:0043547 28 0.051
regulation of signal transduction GO:0009966 135 0.050
macromolecule modification GO:0043412 218 0.050
single organism transport GO:0044765 447 0.050
dna metabolic process GO:0006259 74 0.050
cellular nitrogen compound biosynthetic process GO:0044271 192 0.048
Mouse Fly
chromosome segregation GO:0007059 180 0.047
cellular component movement GO:0006928 388 0.046
body morphogenesis GO:0010171 620 0.046
developmental growth GO:0048589 412 0.046
localization of cell GO:0051674 313 0.046
positive regulation of cellular process GO:0048522 332 0.045
Mouse Fly
positive regulation of small gtpase mediated signal transduction GO:0051057 7 0.044
death GO:0016265 547 0.043
positive regulation of growth GO:0045927 369 0.043
multi multicellular organism process GO:0044706 390 0.043
nucleic acid templated transcription GO:0097659 169 0.042
Mouse Fly
regulation of nuclear division GO:0051783 115 0.041
mitotic cell cycle process GO:1903047 194 0.041
transcription dna templated GO:0006351 168 0.040
Mouse Fly
regulation of gene expression GO:0010468 366 0.040
Mouse Fly
regulation of multicellular organism growth GO:0040014 373 0.039
negative regulation of cellular component organization GO:0051129 33 0.039
regulation of developmental growth GO:0048638 389 0.038
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.038
apoptotic process GO:0006915 478 0.038
regulation of rna biosynthetic process GO:2001141 165 0.037
Mouse Fly
rna metabolic process GO:0016070 228 0.037
Mouse Fly
cell cell signaling GO:0007267 118 0.037
positive regulation of developmental process GO:0051094 408 0.037
carboxylic acid metabolic process GO:0019752 34 0.037
positive regulation of nematode larval development GO:0061063 54 0.037
catabolic process GO:0009056 318 0.036
organonitrogen compound metabolic process GO:1901564 151 0.035
organelle localization GO:0051640 127 0.035
oocyte differentiation GO:0009994 45 0.035
cellular catabolic process GO:0044248 199 0.034
establishment of localization in cell GO:0051649 318 0.033
multi organism behavior GO:0051705 389 0.032
establishment or maintenance of cell polarity GO:0007163 63 0.032
positive regulation of cellular metabolic process GO:0031325 178 0.032
Mouse Fly
macromolecular complex subunit organization GO:0043933 320 0.032
molting cycle GO:0042303 281 0.032
nematode male tail tip morphogenesis GO:0045138 77 0.032
positive regulation of phosphorus metabolic process GO:0010562 56 0.032
protein complex subunit organization GO:0071822 280 0.032
establishment of organelle localization GO:0051656 123 0.031
nucleobase containing compound biosynthetic process GO:0034654 184 0.031
Mouse Fly
regulation of meiosis GO:0040020 94 0.031
positive regulation of post embryonic development GO:0048582 54 0.031
organic cyclic compound catabolic process GO:1901361 119 0.030
intracellular transport GO:0046907 77 0.030
protein phosphorylation GO:0006468 85 0.030
regulation of cell proliferation GO:0042127 105 0.030
regulation of signaling GO:0023051 172 0.030
positive regulation of developmental growth GO:0048639 354 0.030
regulation of cytoskeleton organization GO:0051493 41 0.029
digestive tract development GO:0048565 122 0.029
regulation of cytoplasmic transport GO:1903649 3 0.029
canonical wnt signaling pathway GO:0060070 3 0.029
regulation of macromolecule biosynthetic process GO:0010556 189 0.027
Mouse Fly
secretion GO:0046903 147 0.027
positive regulation of phosphate metabolic process GO:0045937 56 0.027
positive regulation of multicellular organism growth GO:0040018 352 0.027
regulation of rna metabolic process GO:0051252 173 0.026
Mouse Fly
cellular component assembly GO:0022607 293 0.025
negative regulation of macromolecule metabolic process GO:0010605 229 0.025
tube development GO:0035295 126 0.025
growth GO:0040007 562 0.025
heterocycle catabolic process GO:0046700 119 0.025
organic substance catabolic process GO:1901575 294 0.025
rna interference GO:0016246 137 0.025
digestive tract morphogenesis GO:0048546 76 0.025
regulation of phosphorylation GO:0042325 45 0.025
single organism cellular localization GO:1902580 72 0.025
regulation of response to stimulus GO:0048583 243 0.025
regulation of phosphate metabolic process GO:0019220 81 0.025
gene silencing by rna GO:0031047 143 0.025
digestive system development GO:0055123 122 0.024
tissue development GO:0009888 112 0.024
regulation of nucleic acid templated transcription GO:1903506 165 0.023
Mouse Fly
male sex differentiation GO:0046661 86 0.023
macromolecule biosynthetic process GO:0009059 250 0.023
Mouse Fly
cellular lipid metabolic process GO:0044255 40 0.023
behavior GO:0007610 527 0.022
positive regulation of metabolic process GO:0009893 187 0.022
Mouse Fly
posttranscriptional gene silencing by rna GO:0035194 143 0.022
programmed cell death GO:0012501 500 0.022
microtubule based process GO:0007017 182 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.021
Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.021
regulation of phosphorus metabolic process GO:0051174 81 0.021
regulation of cellular biosynthetic process GO:0031326 189 0.021
Mouse Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.020
epidermis development GO:0008544 24 0.020
oocyte development GO:0048599 44 0.020
pattern specification process GO:0007389 59 0.020
Fly
regulation of gene expression epigenetic GO:0040029 163 0.020
Fly
embryonic body morphogenesis GO:0010172 49 0.020
small molecule metabolic process GO:0044281 186 0.020
cellular nitrogen compound catabolic process GO:0044270 119 0.020
cell migration GO:0016477 306 0.020
reproductive behavior GO:0019098 387 0.020
regulation of locomotion GO:0040012 161 0.020
regulation of gtp catabolic process GO:0033124 32 0.019
immune response GO:0006955 192 0.019
positive regulation of signal transduction GO:0009967 40 0.019
positive regulation of macromolecule metabolic process GO:0010604 149 0.019
Mouse Fly
positive regulation of cell communication GO:0010647 69 0.019
male anatomical structure morphogenesis GO:0090598 78 0.019
endomembrane system organization GO:0010256 22 0.018
intracellular signal transduction GO:0035556 96 0.018
response to abiotic stimulus GO:0009628 152 0.018
tube morphogenesis GO:0035239 79 0.018
anatomical structure formation involved in morphogenesis GO:0048646 250 0.018
positive regulation of response to stimulus GO:0048584 55 0.018
cell fate commitment GO:0045165 139 0.018
single organism biosynthetic process GO:0044711 91 0.018
single organism intracellular transport GO:1902582 70 0.018
regulation of vesicle mediated transport GO:0060627 27 0.017
regulation of molecular function GO:0065009 89 0.017
regulation of nucleocytoplasmic transport GO:0046822 3 0.017
asymmetric neuroblast division GO:0055059 8 0.017
posttranscriptional gene silencing GO:0016441 143 0.017
oxoacid metabolic process GO:0043436 47 0.017
memory GO:0007613 3 0.017
cellular protein metabolic process GO:0044267 279 0.017
regulation of canonical wnt signaling pathway GO:0060828 1 0.017
ras protein signal transduction GO:0007265 31 0.017
aromatic compound biosynthetic process GO:0019438 192 0.017
Mouse Fly
positive regulation of gtp catabolic process GO:0033126 28 0.017
nucleoside phosphate catabolic process GO:1901292 77 0.017
regulation of ras protein signal transduction GO:0046578 41 0.017
embryonic morphogenesis GO:0048598 152 0.017
nucleoside phosphate metabolic process GO:0006753 108 0.017
negative regulation of cell cycle GO:0045786 53 0.017
response to endogenous stimulus GO:0009719 33 0.016
actin cytoskeleton reorganization GO:0031532 4 0.016
guanosine containing compound metabolic process GO:1901068 49 0.016
negative regulation of metabolic process GO:0009892 240 0.016
turning behavior involved in mating GO:0034607 12 0.016
organic acid metabolic process GO:0006082 47 0.016
establishment of protein localization to membrane GO:0090150 3 0.016
carbohydrate derivative metabolic process GO:1901135 141 0.016
nervous system development GO:0007399 253 0.016
Fly
nucleotide metabolic process GO:0009117 108 0.015
innate immune response GO:0045087 190 0.015
muscle cell differentiation GO:0042692 171 0.015
organelle assembly GO:0070925 214 0.015
heterocycle biosynthetic process GO:0018130 187 0.015
Mouse Fly
regulation of cell migration GO:0030334 55 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.015
small gtpase mediated signal transduction GO:0007264 32 0.015
cuticle development GO:0042335 100 0.015
ovulation GO:0030728 33 0.015
negative regulation of neurogenesis GO:0050768 4 0.015
striated muscle cell differentiation GO:0051146 158 0.015
organic substance biosynthetic process GO:1901576 323 0.015
Mouse Fly
defense response to bacterium GO:0042742 86 0.015
regulation of multi organism process GO:0043900 69 0.014
cell motility GO:0048870 313 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.014
nucleus localization GO:0051647 55 0.014
macromolecular complex assembly GO:0065003 193 0.014
negative regulation of cellular process GO:0048523 239 0.014
cellular response to stress GO:0033554 162 0.014
amine metabolic process GO:0009308 15 0.014
phosphorus metabolic process GO:0006793 232 0.014
neurogenesis GO:0022008 236 0.014
Fly
cellular amine metabolic process GO:0044106 15 0.014
actin filament based process GO:0030029 191 0.013
oxidation reduction process GO:0055114 59 0.013
cell surface receptor signaling pathway GO:0007166 149 0.013
cellular response to dna damage stimulus GO:0006974 41 0.013
regulation of reproductive process GO:2000241 66 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.013
organic substance transport GO:0071702 113 0.013
defense response to other organism GO:0098542 100 0.013
spindle organization GO:0007051 92 0.013
cellular response to endogenous stimulus GO:0071495 32 0.013
regulation of muscle cell differentiation GO:0051147 1 0.012
cellular response to chemical stimulus GO:0070887 129 0.012
positive regulation of nucleic acid templated transcription GO:1903508 102 0.012
Mouse Fly
nuclear migration GO:0007097 54 0.012
positive regulation of cell migration GO:0030335 3 0.012
positive regulation of neurogenesis GO:0050769 4 0.012
regulation of cell differentiation GO:0045595 81 0.012
cellular component biogenesis GO:0044085 297 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
organelle disassembly GO:1903008 2 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.012
gene silencing GO:0016458 143 0.012
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.012
neuron projection development GO:0031175 187 0.012
Fly
negative regulation of gene expression GO:0010629 217 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
regulation of bmp signaling pathway GO:0030510 3 0.012
epithelial cell proliferation GO:0050673 1 0.012
regulation of cellular response to stress GO:0080135 19 0.012
nuclear transcribed mrna catabolic process GO:0000956 15 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.012
Mouse Fly
aromatic compound catabolic process GO:0019439 116 0.012
cellular protein localization GO:0034613 75 0.012
rna biosynthetic process GO:0032774 169 0.011
Mouse Fly
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
gtp catabolic process GO:0006184 46 0.011
embryonic pattern specification GO:0009880 21 0.011
regulation of transport GO:0051049 91 0.011
protein complex assembly GO:0006461 186 0.011
glycosyl compound metabolic process GO:1901657 100 0.011
cytokinesis GO:0000910 80 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
Mouse Fly
regulation of nucleoside metabolic process GO:0009118 37 0.011
negative regulation of axonogenesis GO:0050771 2 0.011
response to bacterium GO:0009617 86 0.011
macromolecule catabolic process GO:0009057 202 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
response to inorganic substance GO:0010035 50 0.011
regulation of cell motility GO:2000145 57 0.011
regulation of cell communication GO:0010646 176 0.011
oocyte axis specification GO:0007309 2 0.011
system process GO:0003008 136 0.011
regulation of epithelial cell proliferation GO:0050678 1 0.011
cellular macromolecular complex assembly GO:0034622 184 0.011
negative regulation of developmental process GO:0051093 227 0.010
cellular lipid catabolic process GO:0044242 5 0.010
lipid metabolic process GO:0006629 77 0.010
transcription from rna polymerase ii promoter GO:0006366 149 0.010
Mouse
regulation of apoptotic signaling pathway GO:2001233 1 0.010
oocyte construction GO:0007308 2 0.010
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.010
regulation of catabolic process GO:0009894 57 0.010
peptidyl amino acid modification GO:0018193 58 0.010
organophosphate metabolic process GO:0019637 125 0.010
ribonucleoside metabolic process GO:0009119 98 0.010
ribonucleoside triphosphate metabolic process GO:0009199 87 0.010

ash-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.020
muscular disease DOID:0080000 0 0.020
heart disease DOID:114 0 0.020
cardiomyopathy DOID:0050700 0 0.020
disease of anatomical entity DOID:7 0 0.020
cardiovascular system disease DOID:1287 0 0.020
musculoskeletal system disease DOID:17 0 0.020
muscle tissue disease DOID:66 0 0.020
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
dilated cardiomyopathy DOID:12930 0 0.011
intrinsic cardiomyopathy DOID:0060036 0 0.011