Caenorhabditis elegans

20 known processes

phy-2 (CELE_F35G2.4)

Protein PHY-2

phy-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.360
vesicle mediated transport GO:0016192 852 0.281
multicellular organismal reproductive process GO:0048609 815 0.256
death GO:0016265 547 0.235
locomotion GO:0040011 1634 0.205
endocytosis GO:0006897 819 0.202
regulation of developmental process GO:0050793 684 0.186
organ development GO:0048513 1102 0.178
developmental process involved in reproduction GO:0003006 1165 0.165
organelle organization GO:0006996 783 0.162
multicellular organism reproduction GO:0032504 819 0.162
heterocycle biosynthetic process GO:0018130 187 0.160
sex differentiation GO:0007548 909 0.159
regulation of biological quality GO:0065008 741 0.152
cell death GO:0008219 547 0.147
embryo development GO:0009790 3052 0.138
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.134
receptor mediated endocytosis GO:0006898 715 0.131
reproductive system development GO:0061458 850 0.130
genitalia development GO:0048806 741 0.126
hermaphrodite genitalia development GO:0040035 734 0.124
multi organism reproductive process GO:0044703 867 0.123
single organism reproductive process GO:0044702 1196 0.122
embryonic body morphogenesis GO:0010172 49 0.119
macromolecule localization GO:0033036 771 0.119
body morphogenesis GO:0010171 620 0.118
cellular component movement GO:0006928 388 0.115
macromolecular complex subunit organization GO:0043933 320 0.108
gene expression GO:0010467 412 0.107
cell development GO:0048468 696 0.105
cellular macromolecule biosynthetic process GO:0034645 247 0.104
establishment of localization GO:0051234 1171 0.103
regulation of metabolic process GO:0019222 478 0.102
nucleobase containing compound biosynthetic process GO:0034654 184 0.101
muscle organ morphogenesis GO:0048644 4 0.100
maintenance of location GO:0051235 580 0.099
regulation of multicellular organismal process GO:0051239 726 0.099
protein catabolic process GO:0030163 162 0.099
regulation of cell migration GO:0030334 55 0.099
transport GO:0006810 1093 0.096
regulation of rna biosynthetic process GO:2001141 165 0.096
aging GO:0007568 812 0.096
regulation of gene expression GO:0010468 366 0.094
cellular nitrogen compound biosynthetic process GO:0044271 192 0.093
sexual reproduction GO:0019953 546 0.093
regulation of macromolecule metabolic process GO:0060255 421 0.091
gonad development GO:0008406 840 0.091
positive regulation of developmental process GO:0051094 408 0.088
post embryonic development GO:0009791 2152 0.087
positive regulation of developmental growth GO:0048639 354 0.086
oviposition GO:0018991 364 0.085
development of primary sexual characteristics GO:0045137 840 0.083
positive regulation of multicellular organism growth GO:0040018 352 0.083
protein hydroxylation GO:0018126 5 0.081
regulation of transcription dna templated GO:0006355 164 0.079
lipid localization GO:0010876 573 0.079
positive regulation of multicellular organismal process GO:0051240 417 0.079
regulation of nitrogen compound metabolic process GO:0051171 222 0.079
multi organism behavior GO:0051705 389 0.078
apoptotic process GO:0006915 478 0.075
anatomical structure formation involved in morphogenesis GO:0048646 250 0.075
protein modification process GO:0036211 207 0.074
regulation of primary metabolic process GO:0080090 292 0.068
determination of adult lifespan GO:0008340 812 0.067
lipid storage GO:0019915 565 0.067
small molecule metabolic process GO:0044281 186 0.067
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.066
multicellular organism growth GO:0035264 385 0.066
reproductive structure development GO:0048608 850 0.066
cellular protein complex assembly GO:0043623 178 0.065
cellular biosynthetic process GO:0044249 315 0.065
positive regulation of cellular process GO:0048522 332 0.065
multicellular organismal aging GO:0010259 812 0.064
negative regulation of biological process GO:0048519 567 0.063
positive regulation of growth GO:0045927 369 0.062
behavior GO:0007610 527 0.061
regulation of response to stimulus GO:0048583 243 0.061
cell migration GO:0016477 306 0.060
multicellular organismal reproductive behavior GO:0033057 384 0.060
programmed cell death GO:0012501 500 0.059
multi multicellular organism process GO:0044706 390 0.057
single organism organelle organization GO:1902589 501 0.055
nucleobase containing compound metabolic process GO:0006139 406 0.055
reproductive behavior GO:0019098 387 0.053
regulation of developmental growth GO:0048638 389 0.053
regulation of locomotion GO:0040012 161 0.050
muscle cell differentiation GO:0042692 171 0.050
nucleic acid templated transcription GO:0097659 169 0.049
aromatic compound biosynthetic process GO:0019438 192 0.049
growth GO:0040007 562 0.049
oxoacid metabolic process GO:0043436 47 0.048
Mouse
macromolecule biosynthetic process GO:0009059 250 0.047
regulation of multicellular organism growth GO:0040014 373 0.047
signal transduction GO:0007165 317 0.046
regulation of biosynthetic process GO:0009889 189 0.045
striated muscle cell differentiation GO:0051146 158 0.045
germ cell development GO:0007281 351 0.045
multi organism reproductive behavior GO:0044705 387 0.044
regulation of gene expression epigenetic GO:0040029 163 0.043
macromolecular complex assembly GO:0065003 193 0.043
protein complex subunit organization GO:0071822 280 0.041
regulation of growth GO:0040008 409 0.041
gamete generation GO:0007276 461 0.040
myosin filament assembly GO:0031034 138 0.039
chromosome organization GO:0051276 104 0.039
molting cycle GO:0042303 281 0.039
regulation of cellular biosynthetic process GO:0031326 189 0.039
biosynthetic process GO:0009058 323 0.038
striated muscle myosin thick filament assembly GO:0071688 138 0.038
regulation of multicellular organismal development GO:2000026 317 0.037
organic cyclic compound biosynthetic process GO:1901362 195 0.037
cell cycle process GO:0022402 482 0.037
muscle cell development GO:0055001 158 0.037
cellular component biogenesis GO:0044085 297 0.036
negative regulation of vulval development GO:0040027 206 0.035
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.035
protein metabolic process GO:0019538 422 0.034
myosin filament organization GO:0031033 138 0.034
transcription from rna polymerase ii promoter GO:0006366 149 0.034
macromolecule modification GO:0043412 218 0.033
cell cycle GO:0007049 526 0.033
collagen and cuticulin based cuticle development GO:0040002 99 0.033
organ morphogenesis GO:0009887 67 0.033
female gamete generation GO:0007292 254 0.033
response to abiotic stimulus GO:0009628 152 0.032
muscle structure development GO:0061061 191 0.032
developmental growth GO:0048589 412 0.032
meiotic nuclear division GO:0007126 300 0.032
cellular component morphogenesis GO:0032989 318 0.031
organic substance biosynthetic process GO:1901576 323 0.031
cellular protein modification process GO:0006464 207 0.031
oogenesis GO:0048477 229 0.031
establishment of localization in cell GO:0051649 318 0.030
regulation of cell motility GO:2000145 57 0.030
organic acid metabolic process GO:0006082 47 0.030
Mouse
vulval development GO:0040025 333 0.030
posttranscriptional regulation of gene expression GO:0010608 166 0.030
regulation of vulval development GO:0040028 248 0.029
negative regulation of metabolic process GO:0009892 240 0.029
rna biosynthetic process GO:0032774 169 0.029
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.028
myofibril assembly GO:0030239 154 0.028
negative regulation of multicellular organismal process GO:0051241 236 0.028
organelle fission GO:0048285 363 0.028
cellular component assembly involved in morphogenesis GO:0010927 183 0.028
actomyosin structure organization GO:0031032 154 0.028
embryonic morphogenesis GO:0048598 152 0.028
tissue development GO:0009888 112 0.027
regulation of cellular metabolic process GO:0031323 305 0.027
chromosome segregation GO:0007059 180 0.027
regulation of cellular component movement GO:0051270 62 0.027
cellular component assembly GO:0022607 293 0.027
generation of neurons GO:0048699 235 0.026
cuticle development GO:0042335 100 0.026
regulation of signaling GO:0023051 172 0.026
cell motility GO:0048870 313 0.026
regulation of localization GO:0032879 194 0.025
nucleic acid metabolic process GO:0090304 299 0.025
protein complex assembly GO:0006461 186 0.025
regulation of cell communication GO:0010646 176 0.025
protein localization GO:0008104 205 0.025
single organism signaling GO:0044700 401 0.025
actin cytoskeleton organization GO:0030036 184 0.024
negative regulation of macromolecule metabolic process GO:0010605 229 0.024
intracellular signal transduction GO:0035556 96 0.024
cellular response to chemical stimulus GO:0070887 129 0.024
regulation of nematode larval development GO:0061062 260 0.023
cellular protein metabolic process GO:0044267 279 0.023
carboxylic acid metabolic process GO:0019752 34 0.023
Mouse
nervous system development GO:0007399 253 0.023
cellular amino acid metabolic process GO:0006520 15 0.022
Mouse
single organism transport GO:0044765 447 0.021
negative regulation of nematode larval development GO:0061064 208 0.021
organelle assembly GO:0070925 214 0.021
signaling GO:0023052 401 0.021
macromolecule catabolic process GO:0009057 202 0.021
mitotic nuclear envelope reassembly GO:0007084 3 0.021
phagocytosis GO:0006909 115 0.021
phosphate containing compound metabolic process GO:0006796 232 0.021
chromatin organization GO:0006325 32 0.020
nucleoside phosphate metabolic process GO:0006753 108 0.020
carbohydrate derivative metabolic process GO:1901135 141 0.020
cytoskeleton organization GO:0007010 339 0.020
male anatomical structure morphogenesis GO:0090598 78 0.020
cellular macromolecular complex assembly GO:0034622 184 0.020
phosphorus metabolic process GO:0006793 232 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.020
cell proliferation GO:0008283 116 0.019
rna metabolic process GO:0016070 228 0.019
mitotic cell cycle process GO:1903047 194 0.019
chemotaxis GO:0006935 120 0.018
sensory organ morphogenesis GO:0090596 2 0.018
negative regulation of gene expression GO:0010629 217 0.018
cell surface receptor signaling pathway GO:0007166 149 0.018
striated muscle cell development GO:0055002 157 0.018
nematode male tail tip morphogenesis GO:0045138 77 0.018
regulation of signal transduction GO:0009966 135 0.017
regulation of post embryonic development GO:0048580 260 0.017
gene silencing GO:0016458 143 0.017
male sex differentiation GO:0046661 86 0.017
taxis GO:0042330 128 0.017
negative regulation of cellular process GO:0048523 239 0.017
localization of cell GO:0051674 313 0.017
phagocytosis engulfment GO:0006911 98 0.017
tube development GO:0035295 126 0.017
tissue morphogenesis GO:0048729 65 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.016
cellular response to growth factor stimulus GO:0071363 18 0.016
regulation of cell proliferation GO:0042127 105 0.016
negative regulation of gene expression epigenetic GO:0045814 2 0.016
regulation of rna metabolic process GO:0051252 173 0.016
response to chemical GO:0042221 356 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.016
protein complex biogenesis GO:0070271 186 0.016
neuron differentiation GO:0030182 217 0.016
cellular response to stress GO:0033554 162 0.016
regulation of cell differentiation GO:0045595 81 0.015
intracellular transport GO:0046907 77 0.015
muscle tissue development GO:0060537 1 0.015
negative regulation of post embryonic development GO:0048581 208 0.015
negative regulation of developmental process GO:0051093 227 0.015
skeletal muscle organ development GO:0060538 3 0.015
regulation of phagocytosis engulfment GO:0060099 17 0.015
membrane invagination GO:0010324 98 0.014
extracellular structure organization GO:0043062 7 0.014
regulation of phosphorus metabolic process GO:0051174 81 0.014
regulation of nucleic acid templated transcription GO:1903506 165 0.014
regulation of cellular component organization GO:0051128 248 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.013
secondary metabolic process GO:0019748 3 0.013
rna interference GO:0016246 137 0.013
single organism localization GO:1902578 518 0.013
meiotic cell cycle GO:0051321 335 0.013
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
rna localization GO:0006403 3 0.013
actin filament based process GO:0030029 191 0.012
response to wounding GO:0009611 4 0.012
peptidyl amino acid modification GO:0018193 58 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
regulation of organelle organization GO:0033043 164 0.012
organic substance catabolic process GO:1901575 294 0.012
purine containing compound metabolic process GO:0072521 95 0.011
bmp signaling pathway GO:0030509 3 0.011
organonitrogen compound metabolic process GO:1901564 151 0.011
Mouse
single organism intracellular transport GO:1902582 70 0.011
purine nucleoside monophosphate metabolic process GO:0009126 43 0.011
membrane organization GO:0061024 135 0.011
positive regulation of gene expression GO:0010628 112 0.011
gene silencing by rna GO:0031047 143 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.011
single organism membrane organization GO:0044802 35 0.011
regulation of protein localization GO:0032880 50 0.010
positive regulation of cellular biosynthetic process GO:0031328 109 0.010
regulation of cell cycle GO:0051726 194 0.010
adult behavior GO:0030534 3 0.010
cellular localization GO:0051641 360 0.010
apoptotic cell clearance GO:0043277 111 0.010
response to organic substance GO:0010033 131 0.010
negative regulation of response to stimulus GO:0048585 73 0.010
regulation of macromolecule biosynthetic process GO:0010556 189 0.010
post embryonic organ development GO:0048569 336 0.010
localization within membrane GO:0051668 2 0.010

phy-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.020
muscular disease DOID:0080000 0 0.020
heart disease DOID:114 0 0.020
cardiomyopathy DOID:0050700 0 0.020
disease of anatomical entity DOID:7 0 0.020
cardiovascular system disease DOID:1287 0 0.020
musculoskeletal system disease DOID:17 0 0.020
muscle tissue disease DOID:66 0 0.020
dilated cardiomyopathy DOID:12930 0 0.018
intrinsic cardiomyopathy DOID:0060036 0 0.018
muscular dystrophy DOID:9884 0 0.016
limb girdle muscular dystrophy DOID:11724 0 0.016
emery dreifuss muscular dystrophy DOID:11726 0 0.016
progeria DOID:3911 0 0.014