Caenorhabditis elegans

43 known processes

nrde-3 (CELE_R04A9.2)

Protein NRDE-3

nrde-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.778
embryo development GO:0009790 3052 0.633
organ development GO:0048513 1102 0.578
post embryonic development GO:0009791 2152 0.502
Worm
establishment of localization GO:0051234 1171 0.470
sex differentiation GO:0007548 909 0.467
regulation of multicellular organismal development GO:2000026 317 0.455
development of primary sexual characteristics GO:0045137 840 0.432
post embryonic organ development GO:0048569 336 0.431
reproductive system development GO:0061458 850 0.387
regulation of nematode larval development GO:0061062 260 0.348
multicellular organism reproduction GO:0032504 819 0.341
behavior GO:0007610 527 0.335
cell projection organization GO:0030030 231 0.331
negative regulation of developmental process GO:0051093 227 0.320
locomotion GO:0040011 1634 0.313
transcription dna templated GO:0006351 168 0.312
positive regulation of nucleic acid templated transcription GO:1903508 102 0.300
hermaphrodite genitalia development GO:0040035 734 0.297
negative regulation of multicellular organismal process GO:0051241 236 0.294
multicellular organismal reproductive process GO:0048609 815 0.265
organelle organization GO:0006996 783 0.265
single organism transport GO:0044765 447 0.263
regulation of vulval development GO:0040028 248 0.252
vulval development GO:0040025 333 0.249
rna biosynthetic process GO:0032774 169 0.249
negative regulation of vulval development GO:0040027 206 0.246
negative regulation of post embryonic development GO:0048581 208 0.246
regulation of post embryonic development GO:0048580 260 0.235
neuron differentiation GO:0030182 217 0.234
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.224
negative regulation of nematode larval development GO:0061064 208 0.215
cell part morphogenesis GO:0032990 152 0.215
multi organism reproductive process GO:0044703 867 0.200
gonad development GO:0008406 840 0.199
multicellular organismal aging GO:0010259 812 0.195
nervous system development GO:0007399 253 0.195
taxis GO:0042330 128 0.190
cellular biosynthetic process GO:0044249 315 0.188
regulation of nitrogen compound metabolic process GO:0051171 222 0.186
localization of cell GO:0051674 313 0.183
endocytosis GO:0006897 819 0.180
multi multicellular organism process GO:0044706 390 0.169
organic cyclic compound biosynthetic process GO:1901362 195 0.165
developmental process involved in reproduction GO:0003006 1165 0.163
multi organism behavior GO:0051705 389 0.161
cell motility GO:0048870 313 0.160
generation of neurons GO:0048699 235 0.159
macromolecule biosynthetic process GO:0009059 250 0.159
regulation of cellular component organization GO:0051128 248 0.157
oviposition GO:0018991 364 0.152
single organism reproductive process GO:0044702 1196 0.152
rna metabolic process GO:0016070 228 0.150
cellular component movement GO:0006928 388 0.149
negative regulation of macromolecule metabolic process GO:0010605 229 0.149
cell morphogenesis GO:0000902 163 0.148
cellular component morphogenesis GO:0032989 318 0.145
macromolecular complex subunit organization GO:0043933 320 0.141
regulation of rna biosynthetic process GO:2001141 165 0.141
organ morphogenesis GO:0009887 67 0.140
positive regulation of biosynthetic process GO:0009891 109 0.137
neuron projection development GO:0031175 187 0.131
negative regulation of cellular process GO:0048523 239 0.131
regulation of macromolecule metabolic process GO:0060255 421 0.130
vesicle mediated transport GO:0016192 852 0.130
regulation of developmental process GO:0050793 684 0.130
multi organism reproductive behavior GO:0044705 387 0.126
regulation of biological quality GO:0065008 741 0.125
reproductive behavior GO:0019098 387 0.123
protein metabolic process GO:0019538 422 0.123
biosynthetic process GO:0009058 323 0.121
phosphate containing compound metabolic process GO:0006796 232 0.120
transport GO:0006810 1093 0.118
genitalia development GO:0048806 741 0.117
aromatic compound biosynthetic process GO:0019438 192 0.115
nucleic acid metabolic process GO:0090304 299 0.114
reproductive structure development GO:0048608 850 0.112
determination of adult lifespan GO:0008340 812 0.111
cellular protein metabolic process GO:0044267 279 0.108
membrane organization GO:0061024 135 0.105
regulation of multicellular organismal process GO:0051239 726 0.104
response to wounding GO:0009611 4 0.102
neurogenesis GO:0022008 236 0.102
positive regulation of cellular biosynthetic process GO:0031328 109 0.101
nucleobase containing compound metabolic process GO:0006139 406 0.100
neuron development GO:0048666 199 0.098
signaling GO:0023052 401 0.098
single organism localization GO:1902578 518 0.097
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.096
cellular component assembly GO:0022607 293 0.096
actin cytoskeleton organization GO:0030036 184 0.095
positive regulation of transcription dna templated GO:0045893 102 0.094
programmed cell death GO:0012501 500 0.091
receptor mediated endocytosis GO:0006898 715 0.090
cell cell signaling GO:0007267 118 0.089
regulation of response to stimulus GO:0048583 243 0.088
cellular protein modification process GO:0006464 207 0.087
nucleobase containing compound biosynthetic process GO:0034654 184 0.086
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.083
transcription from rna polymerase ii promoter GO:0006366 149 0.082
organic substance biosynthetic process GO:1901576 323 0.081
digestive system development GO:0055123 122 0.081
negative regulation of gene expression GO:0010629 217 0.078
positive regulation of macromolecule metabolic process GO:0010604 149 0.078
cell cycle GO:0007049 526 0.077
regulation of macromolecule biosynthetic process GO:0010556 189 0.076
lipid localization GO:0010876 573 0.075
regulation of signaling GO:0023051 172 0.074
regulation of cell communication GO:0010646 176 0.074
positive regulation of rna biosynthetic process GO:1902680 102 0.074
regulation of cellular metabolic process GO:0031323 305 0.074
response to chemical GO:0042221 356 0.074
positive regulation of gene expression GO:0010628 112 0.073
positive regulation of rna metabolic process GO:0051254 103 0.073
protein complex subunit organization GO:0071822 280 0.070
death GO:0016265 547 0.069
regulation of locomotion GO:0040012 161 0.069
cell division GO:0051301 262 0.069
gene expression GO:0010467 412 0.069
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.069
purine containing compound metabolic process GO:0072521 95 0.068
positive regulation of metabolic process GO:0009893 187 0.067
gamete generation GO:0007276 461 0.067
cell migration GO:0016477 306 0.067
positive regulation of signaling GO:0023056 66 0.065
head development GO:0060322 1 0.065
striated muscle cell development GO:0055002 157 0.064
negative regulation of metabolic process GO:0009892 240 0.063
regulation of biosynthetic process GO:0009889 189 0.063
regulation of primary metabolic process GO:0080090 292 0.062
regulation of cellular biosynthetic process GO:0031326 189 0.062
regulation of rna metabolic process GO:0051252 173 0.060
positive regulation of growth GO:0045927 369 0.060
lipid storage GO:0019915 565 0.059
regulation of transcription dna templated GO:0006355 164 0.058
striated muscle cell differentiation GO:0051146 158 0.058
regulation of nucleic acid templated transcription GO:1903506 165 0.057
maintenance of location GO:0051235 580 0.057
aging GO:0007568 812 0.057
heterocycle biosynthetic process GO:0018130 187 0.056
regulation of molecular function GO:0065009 89 0.056
muscle cell differentiation GO:0042692 171 0.054
cell death GO:0008219 547 0.053
regulation of metabolic process GO:0019222 478 0.051
muscle structure development GO:0061061 191 0.051
macromolecule localization GO:0033036 771 0.051
negative regulation of biological process GO:0048519 567 0.049
cellular component biogenesis GO:0044085 297 0.049
peptidyl tyrosine phosphorylation GO:0018108 2 0.048
cellular ketone metabolic process GO:0042180 14 0.047
positive regulation of cell communication GO:0010647 69 0.047
tube development GO:0035295 126 0.047
single organism organelle organization GO:1902589 501 0.047
growth GO:0040007 562 0.046
regulation of growth GO:0040008 409 0.045
digestive tract development GO:0048565 122 0.045
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.044
axon development GO:0061564 163 0.044
chromosome segregation GO:0007059 180 0.044
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.042
regulation of response to wounding GO:1903034 1 0.042
cellular nitrogen compound biosynthetic process GO:0044271 192 0.042
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.041
protein modification process GO:0036211 207 0.040
immune response GO:0006955 192 0.040
axonogenesis GO:0007409 102 0.040
negative regulation of cellular metabolic process GO:0031324 95 0.039
neuron projection morphogenesis GO:0048812 114 0.039
establishment of organelle localization GO:0051656 123 0.039
small molecule metabolic process GO:0044281 186 0.039
organelle localization GO:0051640 127 0.038
signal transduction GO:0007165 317 0.038
cellular macromolecular complex assembly GO:0034622 184 0.038
regulation of gene expression GO:0010468 366 0.038
cellular macromolecule biosynthetic process GO:0034645 247 0.037
macromolecular complex assembly GO:0065003 193 0.036
regulation of endocytosis GO:0030100 25 0.035
regulation of cellular component movement GO:0051270 62 0.035
tube morphogenesis GO:0035239 79 0.035
actin filament based process GO:0030029 191 0.035
muscle cell development GO:0055001 158 0.035
response to external stimulus GO:0009605 289 0.035
single organism signaling GO:0044700 401 0.034
multicellular organismal reproductive behavior GO:0033057 384 0.034
sexual reproduction GO:0019953 546 0.033
cellular localization GO:0051641 360 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.033
cytoskeleton organization GO:0007010 339 0.033
carbohydrate derivative metabolic process GO:1901135 141 0.033
body morphogenesis GO:0010171 620 0.032
regulation of transport GO:0051049 91 0.032
positive regulation of multicellular organismal process GO:0051240 417 0.032
cell projection morphogenesis GO:0048858 148 0.032
positive regulation of cellular process GO:0048522 332 0.032
intracellular receptor signaling pathway GO:0030522 2 0.031
organonitrogen compound metabolic process GO:1901564 151 0.030
organelle fission GO:0048285 363 0.030
mitotic cell cycle process GO:1903047 194 0.030
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.029
cell development GO:0048468 696 0.029
positive regulation of developmental process GO:0051094 408 0.029
nucleic acid templated transcription GO:0097659 169 0.028
sensory organ morphogenesis GO:0090596 2 0.027
cell cycle process GO:0022402 482 0.027
negative regulation of biosynthetic process GO:0009890 65 0.027
epithelial tube morphogenesis GO:0060562 1 0.027
anatomical structure formation involved in morphogenesis GO:0048646 250 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
regulation of localization GO:0032879 194 0.026
regulation of multicellular organism growth GO:0040014 373 0.026
cellular component assembly involved in morphogenesis GO:0010927 183 0.026
glycosyl compound metabolic process GO:1901657 100 0.026
apoptotic cell clearance GO:0043277 111 0.026
regulation of signal transduction GO:0009966 135 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
cell surface receptor signaling pathway GO:0007166 149 0.025
positive regulation of developmental growth GO:0048639 354 0.025
positive regulation of signal transduction GO:0009967 40 0.025
negative regulation of nucleic acid templated transcription GO:1903507 53 0.025
organic substance catabolic process GO:1901575 294 0.025
synaptic transmission GO:0007268 106 0.024
negative regulation of rna metabolic process GO:0051253 53 0.024
amine metabolic process GO:0009308 15 0.023
tissue morphogenesis GO:0048729 65 0.023
regulation of developmental growth GO:0048638 389 0.023
regulation of phagocytosis engulfment GO:0060099 17 0.023
oxoacid metabolic process GO:0043436 47 0.022
cellular amine metabolic process GO:0044106 15 0.021
cell type specific apoptotic process GO:0097285 4 0.021
neuron recognition GO:0008038 83 0.021
apoptotic process GO:0006915 478 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.020
developmental growth GO:0048589 412 0.020
cell morphogenesis involved in differentiation GO:0000904 112 0.020
posttranscriptional regulation of gene expression GO:0010608 166 0.020
negative regulation of rna biosynthetic process GO:1902679 53 0.020
actomyosin structure organization GO:0031032 154 0.019
organelle assembly GO:0070925 214 0.019
positive regulation of multicellular organism growth GO:0040018 352 0.019
endoplasmic reticulum unfolded protein response GO:0030968 66 0.019
embryonic morphogenesis GO:0048598 152 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.018
macromolecule modification GO:0043412 218 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.018
negative regulation of cellular component organization GO:0051129 33 0.018
regulation of phosphate metabolic process GO:0019220 81 0.018
response to organic substance GO:0010033 131 0.017
inactivation of mapkkk activity GO:0051390 2 0.017
cell recognition GO:0008037 85 0.017
meiotic nuclear division GO:0007126 300 0.017
enzyme linked receptor protein signaling pathway GO:0007167 50 0.016
positive regulation of neuron projection development GO:0010976 4 0.016
organic acid metabolic process GO:0006082 47 0.016
regulation of cell differentiation GO:0045595 81 0.016
regulation of catalytic activity GO:0050790 78 0.016
actin filament organization GO:0007015 21 0.016
locomotory behavior GO:0007626 40 0.016
carboxylic acid metabolic process GO:0019752 34 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.015
negative regulation of signaling GO:0023057 61 0.015
positive regulation of cellular metabolic process GO:0031325 178 0.015
system process GO:0003008 136 0.015
cellular response to stress GO:0033554 162 0.015
negative regulation of cellular biosynthetic process GO:0031327 65 0.015
ras protein signal transduction GO:0007265 31 0.015
cell fate commitment GO:0045165 139 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.014
regulation of protein metabolic process GO:0051246 81 0.014
adult behavior GO:0030534 3 0.014
muscle fiber development GO:0048747 2 0.014
regulation of behavior GO:0050795 97 0.014
regulation of gene expression epigenetic GO:0040029 163 0.014
cellular amino acid metabolic process GO:0006520 15 0.014
regulation of defense response GO:0031347 10 0.014
response to biotic stimulus GO:0009607 101 0.014
single organism behavior GO:0044708 83 0.014
myofibril assembly GO:0030239 154 0.013
digestive tract morphogenesis GO:0048546 76 0.013
multicellular organism growth GO:0035264 385 0.013
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.013
establishment of localization in cell GO:0051649 318 0.013
ribonucleoprotein complex assembly GO:0022618 4 0.013
regulation of protein stability GO:0031647 3 0.013
response to endogenous stimulus GO:0009719 33 0.013
regulation of chromatin modification GO:1903308 2 0.013
positive regulation of protein metabolic process GO:0051247 45 0.013
neuroblast fate specification GO:0014018 4 0.013
dosage compensation GO:0007549 13 0.013
phagocytosis engulfment GO:0006911 98 0.013
protein catabolic process GO:0030163 162 0.013
dosage compensation by hypoactivation of x chromosome GO:0042464 11 0.013
membrane invagination GO:0010324 98 0.012
positive regulation of molecular function GO:0044093 61 0.012
myosin filament organization GO:0031033 138 0.012
canonical wnt signaling pathway GO:0060070 3 0.012
cellular response to organic substance GO:0071310 119 0.012
protein complex assembly GO:0006461 186 0.012
nucleoside metabolic process GO:0009116 99 0.012
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
cellular response to chemical stimulus GO:0070887 129 0.012
male gamete generation GO:0048232 41 0.012
ribonucleotide metabolic process GO:0009259 99 0.012
female gamete generation GO:0007292 254 0.012
regulation of cell migration GO:0030334 55 0.012
organophosphate metabolic process GO:0019637 125 0.011
cell proliferation GO:0008283 116 0.011
positive regulation of intracellular signal transduction GO:1902533 24 0.011
muscle tissue development GO:0060537 1 0.011
germ cell development GO:0007281 351 0.011
axonal fasciculation GO:0007413 79 0.011
single organism catabolic process GO:0044712 129 0.011
ribonucleoside catabolic process GO:0042454 77 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
positive regulation of chromosome organization GO:2001252 2 0.011
cell growth GO:0016049 44 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
positive regulation of cellular component organization GO:0051130 34 0.011
carbohydrate derivative catabolic process GO:1901136 82 0.011
epithelium development GO:0060429 68 0.011
catabolic process GO:0009056 318 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.010
regulation of g protein coupled receptor protein signaling pathway GO:0008277 4 0.010
microtubule based process GO:0007017 182 0.010
regulation of cell cycle process GO:0010564 145 0.010
histone modification GO:0016570 30 0.010
organophosphate catabolic process GO:0046434 81 0.010
regulation of nervous system development GO:0051960 41 0.010
regulation of organelle organization GO:0033043 164 0.010

nrde-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.045
congenital muscular dystrophy DOID:0050557 0 0.045
muscular disease DOID:0080000 0 0.045
muscular dystrophy DOID:9884 0 0.045
disease of anatomical entity DOID:7 0 0.045
musculoskeletal system disease DOID:17 0 0.045
muscle tissue disease DOID:66 0 0.045