Caenorhabditis elegans

2 known processes

unc-8 (CELE_R13A1.4)

Protein UNC-8

unc-8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.247
post embryonic development GO:0009791 2152 0.218
embryo development GO:0009790 3052 0.180
developmental process involved in reproduction GO:0003006 1165 0.131
regulation of developmental process GO:0050793 684 0.123
Mouse
growth GO:0040007 562 0.121
sex differentiation GO:0007548 909 0.119
vesicle mediated transport GO:0016192 852 0.118
locomotion GO:0040011 1634 0.117
multicellular organismal aging GO:0010259 812 0.114
establishment of localization GO:0051234 1171 0.111
Mouse
endocytosis GO:0006897 819 0.106
determination of adult lifespan GO:0008340 812 0.106
aging GO:0007568 812 0.097
transport GO:0006810 1093 0.092
Mouse
single organism reproductive process GO:0044702 1196 0.091
multicellular organism reproduction GO:0032504 819 0.090
organ development GO:0048513 1102 0.088
hermaphrodite genitalia development GO:0040035 734 0.085
genitalia development GO:0048806 741 0.082
reproductive system development GO:0061458 850 0.082
cell development GO:0048468 696 0.076
regulation of biological quality GO:0065008 741 0.075
Mouse
regulation of multicellular organismal process GO:0051239 726 0.072
Mouse
development of primary sexual characteristics GO:0045137 840 0.072
regulation of growth GO:0040008 409 0.072
organelle organization GO:0006996 783 0.071
multi organism reproductive process GO:0044703 867 0.071
multicellular organism growth GO:0035264 385 0.071
regulation of developmental growth GO:0048638 389 0.069
positive regulation of multicellular organism growth GO:0040018 352 0.068
developmental growth GO:0048589 412 0.066
lipid localization GO:0010876 573 0.066
reproductive structure development GO:0048608 850 0.066
maintenance of location GO:0051235 580 0.066
negative regulation of biological process GO:0048519 567 0.064
Mouse
lipid storage GO:0019915 565 0.063
receptor mediated endocytosis GO:0006898 715 0.063
macromolecule localization GO:0033036 771 0.061
Mouse
single organism organelle organization GO:1902589 501 0.061
multi organism behavior GO:0051705 389 0.061
death GO:0016265 547 0.059
Mouse
multicellular organismal reproductive process GO:0048609 815 0.059
positive regulation of developmental process GO:0051094 408 0.059
Mouse
regulation of multicellular organism growth GO:0040014 373 0.057
body morphogenesis GO:0010171 620 0.056
single organism localization GO:1902578 518 0.056
Mouse
sexual reproduction GO:0019953 546 0.055
gonad development GO:0008406 840 0.054
multicellular organismal reproductive behavior GO:0033057 384 0.052
positive regulation of multicellular organismal process GO:0051240 417 0.052
Mouse
cellular component movement GO:0006928 388 0.051
cellular component biogenesis GO:0044085 297 0.051
Mouse
positive regulation of developmental growth GO:0048639 354 0.051
cytoskeleton organization GO:0007010 339 0.051
behavior GO:0007610 527 0.050
Mouse
positive regulation of growth GO:0045927 369 0.048
cellular component assembly GO:0022607 293 0.048
Mouse
multi multicellular organism process GO:0044706 390 0.047
cellular localization GO:0051641 360 0.047
Mouse
single organism transport GO:0044765 447 0.047
Mouse
establishment of localization in cell GO:0051649 318 0.046
Mouse
regulation of metabolic process GO:0019222 478 0.046
macromolecular complex subunit organization GO:0043933 320 0.046
oviposition GO:0018991 364 0.045
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.045
programmed cell death GO:0012501 500 0.044
Mouse
macromolecular complex assembly GO:0065003 193 0.044
cellular component morphogenesis GO:0032989 318 0.043
molting cycle GO:0042303 281 0.043
protein complex subunit organization GO:0071822 280 0.042
macromolecule modification GO:0043412 218 0.042
muscle tissue development GO:0060537 1 0.042
response to external stimulus GO:0009605 289 0.041
Mouse
multi organism reproductive behavior GO:0044705 387 0.040
response to chemical GO:0042221 356 0.040
Mouse
neuron development GO:0048666 199 0.040
actin filament based process GO:0030029 191 0.039
protein complex assembly GO:0006461 186 0.038
muscle structure development GO:0061061 191 0.038
protein modification process GO:0036211 207 0.037
muscle cell differentiation GO:0042692 171 0.037
female gamete generation GO:0007292 254 0.037
cellular protein metabolic process GO:0044267 279 0.036
muscle cell development GO:0055001 158 0.036
cell motility GO:0048870 313 0.036
germ cell development GO:0007281 351 0.036
cellular component assembly involved in morphogenesis GO:0010927 183 0.036
reproductive behavior GO:0019098 387 0.036
cell death GO:0008219 547 0.035
Mouse
cellular protein modification process GO:0006464 207 0.034
ion transmembrane transport GO:0034220 91 0.034
Mouse
nervous system development GO:0007399 253 0.033
Mouse
system process GO:0003008 136 0.033
Mouse
apoptotic process GO:0006915 478 0.032
Mouse
regulation of multicellular organismal development GO:2000026 317 0.032
Mouse
single organism signaling GO:0044700 401 0.032
Mouse
gamete generation GO:0007276 461 0.032
synaptic transmission GO:0007268 106 0.032
Mouse
small molecule metabolic process GO:0044281 186 0.032
taxis GO:0042330 128 0.032
negative regulation of multicellular organismal process GO:0051241 236 0.032
generation of neurons GO:0048699 235 0.031
skeletal muscle organ development GO:0060538 3 0.031
secretion GO:0046903 147 0.031
Mouse
regulation of response to stimulus GO:0048583 243 0.030
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.030
localization of cell GO:0051674 313 0.030
signaling GO:0023052 401 0.029
Mouse
response to wounding GO:0009611 4 0.029
negative regulation of developmental process GO:0051093 227 0.028
organic substance catabolic process GO:1901575 294 0.028
transmembrane transport GO:0055085 110 0.028
Mouse
regulation of cation channel activity GO:2001257 3 0.027
anatomical structure formation involved in morphogenesis GO:0048646 250 0.027
protein metabolic process GO:0019538 422 0.027
cellular protein complex assembly GO:0043623 178 0.027
cellular macromolecular complex assembly GO:0034622 184 0.027
regulation of transport GO:0051049 91 0.027
Mouse
chemotaxis GO:0006935 120 0.026
actin cytoskeleton organization GO:0030036 184 0.026
oogenesis GO:0048477 229 0.026
actomyosin structure organization GO:0031032 154 0.026
neuron differentiation GO:0030182 217 0.026
striated muscle myosin thick filament assembly GO:0071688 138 0.026
protein complex biogenesis GO:0070271 186 0.025
myofibril assembly GO:0030239 154 0.025
head development GO:0060322 1 0.025
phosphate containing compound metabolic process GO:0006796 232 0.025
organonitrogen compound metabolic process GO:1901564 151 0.025
regulation of signaling GO:0023051 172 0.024
Mouse
phosphorus metabolic process GO:0006793 232 0.024
eating behavior GO:0042755 59 0.024
striated muscle cell differentiation GO:0051146 158 0.024
cell migration GO:0016477 306 0.024
catabolic process GO:0009056 318 0.024
cell projection organization GO:0030030 231 0.024
regulation of reproductive process GO:2000241 66 0.023
organic substance biosynthetic process GO:1901576 323 0.023
neurotransmitter catabolic process GO:0042135 4 0.023
regulation of macromolecule metabolic process GO:0060255 421 0.023
gene expression GO:0010467 412 0.023
nucleobase containing compound metabolic process GO:0006139 406 0.023
regulation of cellular metabolic process GO:0031323 305 0.023
inactivation of mapkkk activity GO:0051390 2 0.022
regulation of cellular component organization GO:0051128 248 0.022
Mouse
protein localization GO:0008104 205 0.022
Mouse
neuron projection development GO:0031175 187 0.022
metal ion transport GO:0030001 49 0.022
Mouse
cell type specific apoptotic process GO:0097285 4 0.021
inductive cell migration GO:0040039 145 0.021
calcium mediated signaling GO:0019722 3 0.021
regulation of synaptic transmission GO:0050804 34 0.021
Mouse
cell morphogenesis GO:0000902 163 0.021
cellular biosynthetic process GO:0044249 315 0.021
cell cell signaling GO:0007267 118 0.021
Mouse
biosynthetic process GO:0009058 323 0.021
regulation of feeding behavior GO:0060259 38 0.020
defecation rhythm GO:0035882 3 0.020
regulation of pharyngeal pumping GO:0043051 36 0.020
regulation of neuromuscular synaptic transmission GO:1900073 1 0.020
regulation of defecation rhythm GO:2000746 3 0.020
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.020
neurogenesis GO:0022008 236 0.019
feeding behavior GO:0007631 70 0.019
pharyngeal pumping GO:0043050 58 0.019
organic substance transport GO:0071702 113 0.019
Mouse
negative regulation of metabolic process GO:0009892 240 0.019
carbohydrate derivative metabolic process GO:1901135 141 0.019
positive regulation of cellular process GO:0048522 332 0.019
Mouse
cellular response to organic substance GO:0071310 119 0.019
cation transport GO:0006812 78 0.018
Mouse
phosphorylation GO:0016310 116 0.018
regulation of primary metabolic process GO:0080090 292 0.018
response to organic substance GO:0010033 131 0.018
regulation of localization GO:0032879 194 0.018
Mouse
acetylcholine catabolic process GO:0006581 4 0.018
regulation of multi organism process GO:0043900 69 0.017
regulation of cell division GO:0051302 142 0.017
organic acid metabolic process GO:0006082 47 0.017
ion transport GO:0006811 113 0.017
Mouse
myosin filament organization GO:0031033 138 0.017
myosin filament assembly GO:0031034 138 0.017
muscle system process GO:0003012 43 0.017
organelle assembly GO:0070925 214 0.017
cell division GO:0051301 262 0.017
negative regulation of macromolecule metabolic process GO:0010605 229 0.017
nitrogen compound transport GO:0071705 49 0.017
single organism catabolic process GO:0044712 129 0.017
regulation of locomotion GO:0040012 161 0.016
neuromuscular junction development GO:0007528 2 0.016
intercellular transport GO:0010496 1 0.016
cell cycle process GO:0022402 482 0.016
muscle contraction GO:0006936 43 0.016
cellular catabolic process GO:0044248 199 0.016
regulation of cytoplasmic transport GO:1903649 3 0.016
striated muscle cell development GO:0055002 157 0.016
single organism cellular localization GO:1902580 72 0.016
secretion by cell GO:0032940 138 0.016
Mouse
regulation of synapse assembly GO:0051963 2 0.016
Mouse
excretion GO:0007588 49 0.016
response to abiotic stimulus GO:0009628 152 0.016
Mouse
axon development GO:0061564 163 0.016
regulation of cell communication GO:0010646 176 0.016
Mouse
adult behavior GO:0030534 3 0.016
oxoacid metabolic process GO:0043436 47 0.016
regulation of gene expression GO:0010468 366 0.016
protein phosphorylation GO:0006468 85 0.015
memory GO:0007613 3 0.015
Mouse
organelle fission GO:0048285 363 0.015
cellular amine metabolic process GO:0044106 15 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
protein oligomerization GO:0051259 4 0.015
regulation of behavior GO:0050795 97 0.015
macromolecule biosynthetic process GO:0009059 250 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.015
regulation of post embryonic development GO:0048580 260 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
negative regulation of transporter activity GO:0032410 3 0.014
regulation of epithelial cell proliferation GO:0050678 1 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
negative regulation of post embryonic development GO:0048581 208 0.014
carboxylic acid metabolic process GO:0019752 34 0.014
regulation of response to wounding GO:1903034 1 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.014
defense response GO:0006952 296 0.014
signal transduction GO:0007165 317 0.014
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
immune response GO:0006955 192 0.014
regulation of ion transport GO:0043269 39 0.014
Mouse
embryonic body morphogenesis GO:0010172 49 0.014
chromosome segregation GO:0007059 180 0.014
collagen and cuticulin based cuticle development GO:0040002 99 0.014
negative regulation of neurogenesis GO:0050768 4 0.014
adult locomotory behavior GO:0008344 1 0.014
amine metabolic process GO:0009308 15 0.014
regulation of nitrogen compound metabolic process GO:0051171 222 0.013
negative regulation of gene expression GO:0010629 217 0.013
post embryonic organ development GO:0048569 336 0.013
regulation of signal transduction GO:0009966 135 0.013
canonical wnt signaling pathway GO:0060070 3 0.013
peptidyl tyrosine phosphorylation GO:0018108 2 0.013
membrane organization GO:0061024 135 0.013
gene silencing by rna GO:0031047 143 0.013
male anatomical structure morphogenesis GO:0090598 78 0.013
rna interference GO:0016246 137 0.013
rna metabolic process GO:0016070 228 0.013
negative regulation of ion transmembrane transport GO:0034766 3 0.013
cuticle development GO:0042335 100 0.013
negative regulation of cation channel activity GO:2001258 2 0.013
regulation of intracellular signal transduction GO:1902531 77 0.012
defense response to other organism GO:0098542 100 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
embryonic morphogenesis GO:0048598 152 0.012
nucleic acid metabolic process GO:0090304 299 0.012
negative regulation of transmembrane transport GO:0034763 3 0.012
cellular ketone metabolic process GO:0042180 14 0.012
ribose phosphate metabolic process GO:0019693 99 0.012
regulation of cell cycle GO:0051726 194 0.012
ribonucleoside metabolic process GO:0009119 98 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
cellular macromolecule biosynthetic process GO:0034645 247 0.012
cell part morphogenesis GO:0032990 152 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
positive regulation of cell migration GO:0030335 3 0.012
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
posttranscriptional gene silencing GO:0016441 143 0.012
negative regulation of cellular process GO:0048523 239 0.012
Mouse
regulation of nematode larval development GO:0061062 260 0.012
regulation of oviposition GO:0046662 43 0.012
hormone transport GO:0009914 2 0.012
cell projection morphogenesis GO:0048858 148 0.012
vulval development GO:0040025 333 0.012
mitotic spindle organization GO:0007052 81 0.012
rna biosynthetic process GO:0032774 169 0.012
cell substrate adhesion GO:0031589 1 0.011
establishment of spindle orientation GO:0051294 34 0.011
muscle fiber development GO:0048747 2 0.011
membrane depolarization GO:0051899 1 0.011
neuron projection morphogenesis GO:0048812 114 0.011
ribonucleoprotein complex assembly GO:0022618 4 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.011
heterocycle catabolic process GO:0046700 119 0.011
innate immune response GO:0045087 190 0.011
regulation of striated muscle contraction GO:0006942 4 0.011
regulation of cell differentiation GO:0045595 81 0.011
response to external biotic stimulus GO:0043207 101 0.011
male sex differentiation GO:0046661 86 0.011
regulation of phosphate metabolic process GO:0019220 81 0.011
striated muscle contraction GO:0006941 17 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
regulation of protein targeting GO:1903533 3 0.011
meiotic cell cycle process GO:1903046 170 0.011
nematode male tail tip morphogenesis GO:0045138 77 0.011
regulation of system process GO:0044057 27 0.011
Mouse
divalent inorganic cation transport GO:0072511 17 0.011
Mouse
purine nucleotide metabolic process GO:0006163 95 0.011
cellular response to stress GO:0033554 162 0.011
cell cycle GO:0007049 526 0.011
intracellular signal transduction GO:0035556 96 0.011
cation transmembrane transport GO:0098655 59 0.011
Mouse
regulation of cell proliferation GO:0042127 105 0.011
regulation of organelle organization GO:0033043 164 0.011
regulation of molecular function GO:0065009 89 0.011
epithelial cell proliferation GO:0050673 1 0.011
response to other organism GO:0051707 101 0.011
axonogenesis GO:0007409 102 0.011
organic cyclic compound catabolic process GO:1901361 119 0.010
establishment of organelle localization GO:0051656 123 0.010
detection of external stimulus GO:0009581 4 0.010
Mouse
signal release GO:0023061 28 0.010
Mouse
acetate ester metabolic process GO:1900619 4 0.010
positive regulation of striated muscle contraction GO:0045989 2 0.010
acetylcholine metabolic process GO:0008291 4 0.010
regulation of hormone secretion GO:0046883 2 0.010
organonitrogen compound catabolic process GO:1901565 90 0.010
macromolecule catabolic process GO:0009057 202 0.010
mitotic cell cycle process GO:1903047 194 0.010
positive regulation of cellular metabolic process GO:0031325 178 0.010
neuromuscular process GO:0050905 1 0.010
purine nucleoside metabolic process GO:0042278 92 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010

unc-8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.010