Caenorhabditis elegans

63 known processes

sphk-1 (CELE_C34C6.5)

Protein SPHK-1

sphk-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization GO:0051234 1171 0.261
post embryonic development GO:0009791 2152 0.200
embryo development ending in birth or egg hatching GO:0009792 2992 0.193
locomotion GO:0040011 1634 0.182
transport GO:0006810 1093 0.165
embryo development GO:0009790 3052 0.145
organ development GO:0048513 1102 0.142
Mouse
aging GO:0007568 812 0.119
reproductive structure development GO:0048608 850 0.118
developmental process involved in reproduction GO:0003006 1165 0.102
cell development GO:0048468 696 0.098
endocytosis GO:0006897 819 0.095
determination of adult lifespan GO:0008340 812 0.092
multicellular organismal aging GO:0010259 812 0.088
macromolecule localization GO:0033036 771 0.087
development of primary sexual characteristics GO:0045137 840 0.084
multicellular organism reproduction GO:0032504 819 0.083
Fly
reproductive system development GO:0061458 850 0.078
single organism reproductive process GO:0044702 1196 0.078
receptor mediated endocytosis GO:0006898 715 0.076
regulation of biological quality GO:0065008 741 0.073
vesicle mediated transport GO:0016192 852 0.072
lipid localization GO:0010876 573 0.067
single organism organelle organization GO:1902589 501 0.065
maintenance of location GO:0051235 580 0.063
lipid storage GO:0019915 565 0.063
body morphogenesis GO:0010171 620 0.063
multicellular organismal reproductive process GO:0048609 815 0.063
Fly
gonad development GO:0008406 840 0.060
cellular biosynthetic process GO:0044249 315 0.060
cell migration GO:0016477 306 0.057
death GO:0016265 547 0.055
localization of cell GO:0051674 313 0.055
cellular component movement GO:0006928 388 0.055
protein metabolic process GO:0019538 422 0.054
organelle organization GO:0006996 783 0.054
sex differentiation GO:0007548 909 0.054
small molecule metabolic process GO:0044281 186 0.051
Mouse
biosynthetic process GO:0009058 323 0.051
negative regulation of biological process GO:0048519 567 0.051
genitalia development GO:0048806 741 0.050
gamete generation GO:0007276 461 0.050
regulation of macromolecule metabolic process GO:0060255 421 0.050
positive regulation of developmental process GO:0051094 408 0.049
organic substance biosynthetic process GO:1901576 323 0.049
regulation of developmental process GO:0050793 684 0.049
positive regulation of growth GO:0045927 369 0.048
cytoskeleton organization GO:0007010 339 0.048
phosphate containing compound metabolic process GO:0006796 232 0.048
Mouse Fly
catabolic process GO:0009056 318 0.047
microtubule based process GO:0007017 182 0.047
organic substance catabolic process GO:1901575 294 0.046
positive regulation of cellular process GO:0048522 332 0.045
growth GO:0040007 562 0.045
cell death GO:0008219 547 0.044
sexual reproduction GO:0019953 546 0.043
apoptotic process GO:0006915 478 0.042
organelle fission GO:0048285 363 0.042
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.042
cell motility GO:0048870 313 0.042
signaling GO:0023052 401 0.041
neuron differentiation GO:0030182 217 0.040
regulation of developmental growth GO:0048638 389 0.040
female gamete generation GO:0007292 254 0.040
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.039
molting cycle GO:0042303 281 0.039
multi organism reproductive process GO:0044703 867 0.038
Fly
vulval development GO:0040025 333 0.038
organonitrogen compound metabolic process GO:1901564 151 0.038
Mouse Fly
programmed cell death GO:0012501 500 0.038
single organism transport GO:0044765 447 0.037
nucleobase containing compound metabolic process GO:0006139 406 0.037
positive regulation of multicellular organismal process GO:0051240 417 0.037
positive regulation of developmental growth GO:0048639 354 0.037
behavior GO:0007610 527 0.036
Fly
gene expression GO:0010467 412 0.036
signal transduction GO:0007165 317 0.036
response to external stimulus GO:0009605 289 0.036
regulation of multicellular organism growth GO:0040014 373 0.035
regulation of multicellular organismal process GO:0051239 726 0.035
Mouse
regulation of gene expression GO:0010468 366 0.035
multi organism behavior GO:0051705 389 0.035
Fly
single organism localization GO:1902578 518 0.035
regulation of growth GO:0040008 409 0.034
developmental growth GO:0048589 412 0.034
cellular macromolecule biosynthetic process GO:0034645 247 0.034
cell cycle GO:0007049 526 0.034
phosphorus metabolic process GO:0006793 232 0.034
Mouse Fly
regulation of metabolic process GO:0019222 478 0.034
muscle tissue development GO:0060537 1 0.034
cellular localization GO:0051641 360 0.034
oogenesis GO:0048477 229 0.033
cell cycle process GO:0022402 482 0.033
multicellular organism growth GO:0035264 385 0.033
multicellular organismal reproductive behavior GO:0033057 384 0.033
Fly
neurogenesis GO:0022008 236 0.033
positive regulation of multicellular organism growth GO:0040018 352 0.032
nucleotide metabolic process GO:0009117 108 0.032
regulation of locomotion GO:0040012 161 0.032
post embryonic organ development GO:0048569 336 0.031
cellular protein metabolic process GO:0044267 279 0.031
positive regulation of cellular metabolic process GO:0031325 178 0.031
neuron development GO:0048666 199 0.031
hermaphrodite genitalia development GO:0040035 734 0.030
cell projection organization GO:0030030 231 0.030
establishment of localization in cell GO:0051649 318 0.030
rna localization GO:0006403 3 0.030
generation of neurons GO:0048699 235 0.030
macromolecule biosynthetic process GO:0009059 250 0.029
cellular component morphogenesis GO:0032989 318 0.029
germ cell development GO:0007281 351 0.029
macromolecular complex subunit organization GO:0043933 320 0.029
reproductive behavior GO:0019098 387 0.028
Fly
regulation of post embryonic development GO:0048580 260 0.028
oviposition GO:0018991 364 0.028
Fly
protein complex subunit organization GO:0071822 280 0.027
meiotic cell cycle GO:0051321 335 0.027
negative regulation of post embryonic development GO:0048581 208 0.027
negative regulation of developmental process GO:0051093 227 0.027
single organism signaling GO:0044700 401 0.026
macromolecule catabolic process GO:0009057 202 0.025
rna interference GO:0016246 137 0.025
aromatic compound biosynthetic process GO:0019438 192 0.025
nervous system development GO:0007399 253 0.025
Mouse
gene silencing GO:0016458 143 0.025
posttranscriptional regulation of gene expression GO:0010608 166 0.025
lipid metabolic process GO:0006629 77 0.025
Mouse Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.024
organophosphate metabolic process GO:0019637 125 0.024
macromolecular complex assembly GO:0065003 193 0.024
regulation of nitrogen compound metabolic process GO:0051171 222 0.023
posttranscriptional gene silencing GO:0016441 143 0.023
carbohydrate derivative metabolic process GO:1901135 141 0.023
cellular component biogenesis GO:0044085 297 0.023
posttranscriptional gene silencing by rna GO:0035194 143 0.023
protein modification process GO:0036211 207 0.023
organic acid metabolic process GO:0006082 47 0.023
regulation of gene expression epigenetic GO:0040029 163 0.023
response to chemical GO:0042221 356 0.023
negative regulation of gene expression GO:0010629 217 0.022
macromolecule modification GO:0043412 218 0.022
nucleobase containing small molecule metabolic process GO:0055086 115 0.022
regulation of cellular metabolic process GO:0031323 305 0.022
nucleic acid metabolic process GO:0090304 299 0.022
single organism biosynthetic process GO:0044711 91 0.022
protein localization GO:0008104 205 0.022
gene silencing by rna GO:0031047 143 0.022
mitotic nuclear division GO:0007067 89 0.022
multi multicellular organism process GO:0044706 390 0.022
Fly
oxoacid metabolic process GO:0043436 47 0.021
head development GO:0060322 1 0.021
Mouse
negative regulation of nematode larval development GO:0061064 208 0.021
organelle localization GO:0051640 127 0.021
purine nucleoside metabolic process GO:0042278 92 0.021
muscle structure development GO:0061061 191 0.021
axon development GO:0061564 163 0.020
negative regulation of macromolecule metabolic process GO:0010605 229 0.020
regulation of multicellular organismal development GO:2000026 317 0.020
rrna metabolic process GO:0016072 3 0.020
cellular protein modification process GO:0006464 207 0.020
organophosphate catabolic process GO:0046434 81 0.020
cell projection morphogenesis GO:0048858 148 0.020
chromosome segregation GO:0007059 180 0.020
ribonucleoside metabolic process GO:0009119 98 0.020
organic cyclic compound catabolic process GO:1901361 119 0.019
cellular catabolic process GO:0044248 199 0.019
ribosome biogenesis GO:0042254 4 0.019
positive regulation of cell projection organization GO:0031346 4 0.019
heterocycle biosynthetic process GO:0018130 187 0.019
regulation of localization GO:0032879 194 0.018
defense response GO:0006952 296 0.018
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.018
nucleobase containing compound catabolic process GO:0034655 114 0.018
regulation of cellular component organization GO:0051128 248 0.018
purine nucleoside triphosphate catabolic process GO:0009146 72 0.018
cellular protein complex assembly GO:0043623 178 0.018
muscle cell differentiation GO:0042692 171 0.018
regulation of vulval development GO:0040028 248 0.018
glycosyl compound metabolic process GO:1901657 100 0.018
nucleoside phosphate metabolic process GO:0006753 108 0.018
mitotic cell cycle process GO:1903047 194 0.018
rna metabolic process GO:0016070 228 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.017
striated muscle cell differentiation GO:0051146 158 0.017
cell division GO:0051301 262 0.017
negative regulation of metabolic process GO:0009892 240 0.017
muscle organ morphogenesis GO:0048644 4 0.017
multi organism reproductive behavior GO:0044705 387 0.017
Fly
collagen and cuticulin based cuticle development GO:0040002 99 0.017
carboxylic acid metabolic process GO:0019752 34 0.017
cellular component assembly GO:0022607 293 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.017
positive regulation of metabolic process GO:0009893 187 0.017
muscle cell development GO:0055001 158 0.017
regulation of nematode larval development GO:0061062 260 0.017
protein complex biogenesis GO:0070271 186 0.017
response to wounding GO:0009611 4 0.016
oocyte construction GO:0007308 2 0.016
actin filament based process GO:0030029 191 0.016
cell surface receptor signaling pathway GO:0007166 149 0.016
striated muscle cell development GO:0055002 157 0.016
purine containing compound metabolic process GO:0072521 95 0.016
cell part morphogenesis GO:0032990 152 0.016
purine ribonucleoside metabolic process GO:0046128 92 0.015
heterocycle catabolic process GO:0046700 119 0.015
nucleotide catabolic process GO:0009166 77 0.015
nucleoside phosphate catabolic process GO:1901292 77 0.015
chemotaxis GO:0006935 120 0.015
small molecule biosynthetic process GO:0044283 38 0.015
sensory organ morphogenesis GO:0090596 2 0.015
purine nucleotide catabolic process GO:0006195 75 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
nucleoside metabolic process GO:0009116 99 0.015
cell morphogenesis GO:0000902 163 0.014
negative regulation of vulval development GO:0040027 206 0.014
regulation of primary metabolic process GO:0080090 292 0.014
cellular nitrogen compound biosynthetic process GO:0044271 192 0.014
cellular nitrogen compound catabolic process GO:0044270 119 0.014
negative regulation of multicellular organismal process GO:0051241 236 0.014
protein catabolic process GO:0030163 162 0.014
myosin filament assembly GO:0031034 138 0.014
regulation of nuclear division GO:0051783 115 0.014
regulation of signaling GO:0023051 172 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.014
response to abiotic stimulus GO:0009628 152 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
inductive cell migration GO:0040039 145 0.014
rrna processing GO:0006364 3 0.014
myosin filament organization GO:0031033 138 0.014
meiotic nuclear division GO:0007126 300 0.014
purine nucleoside triphosphate metabolic process GO:0009144 87 0.013
innate immune response GO:0045087 190 0.013
organelle assembly GO:0070925 214 0.013
ribonucleotide catabolic process GO:0009261 75 0.013
purine ribonucleotide catabolic process GO:0009154 75 0.013
cellular response to abiotic stimulus GO:0071214 4 0.013
cell morphogenesis involved in differentiation GO:0000904 112 0.013
protein complex assembly GO:0006461 186 0.013
ribonucleoside catabolic process GO:0042454 77 0.013
nucleoside catabolic process GO:0009164 78 0.013
regulation of transcription dna templated GO:0006355 164 0.013
translation GO:0006412 37 0.013
myofibril assembly GO:0030239 154 0.013
regulation of cell projection assembly GO:0060491 3 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.012
regulation of synapse assembly GO:0051963 2 0.012
regulation of transport GO:0051049 91 0.012
cellular macromolecular complex assembly GO:0034622 184 0.012
ribonucleoside triphosphate metabolic process GO:0009199 87 0.012
purine nucleotide metabolic process GO:0006163 95 0.012
regulation of cell cycle GO:0051726 194 0.012
carbohydrate derivative catabolic process GO:1901136 82 0.012
neuron projection development GO:0031175 187 0.012
secretion GO:0046903 147 0.012
purine ribonucleoside catabolic process GO:0046130 75 0.012
meiotic cell cycle process GO:1903046 170 0.012
cell fate commitment GO:0045165 139 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
engulfment of apoptotic cell GO:0043652 94 0.012
neuron projection morphogenesis GO:0048812 114 0.012
glycosyl compound catabolic process GO:1901658 79 0.012
neuromuscular junction development GO:0007528 2 0.012
mating GO:0007618 34 0.012
regulation of reproductive process GO:2000241 66 0.012
protein oligomerization GO:0051259 4 0.012
spindle organization GO:0007051 92 0.012
ribonucleotide metabolic process GO:0009259 99 0.012
meiotic chromosome segregation GO:0045132 139 0.012
ribose phosphate metabolic process GO:0019693 99 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.011
nucleobase containing compound biosynthetic process GO:0034654 184 0.011
oxidation reduction process GO:0055114 59 0.011
cell type specific apoptotic process GO:0097285 4 0.011
organonitrogen compound biosynthetic process GO:1901566 44 0.011
regulation of organelle organization GO:0033043 164 0.011
regulation of cell cycle process GO:0010564 145 0.011
secretion by cell GO:0032940 138 0.011
epithelial tube morphogenesis GO:0060562 1 0.011
aromatic compound catabolic process GO:0019439 116 0.011
membrane invagination GO:0010324 98 0.011
establishment of organelle localization GO:0051656 123 0.011
negative regulation of gene expression epigenetic GO:0045814 2 0.011
apoptotic cell clearance GO:0043277 111 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.011
regulation of signal transduction GO:0009966 135 0.011
cellular component assembly involved in morphogenesis GO:0010927 183 0.011
gtp metabolic process GO:0046039 46 0.011
actomyosin structure organization GO:0031032 154 0.011
purine nucleoside catabolic process GO:0006152 75 0.011
regulation of cell division GO:0051302 142 0.011
regulation of cell communication GO:0010646 176 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.010
membrane organization GO:0061024 135 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.010
defense response to bacterium GO:0042742 86 0.010
positive regulation of neurogenesis GO:0050769 4 0.010
canonical wnt signaling pathway GO:0060070 3 0.010
transcription from rna polymerase ii promoter GO:0006366 149 0.010
system process GO:0003008 136 0.010
actin cytoskeleton organization GO:0030036 184 0.010
cellular ketone metabolic process GO:0042180 14 0.010
neuron projection guidance GO:0097485 82 0.010
single organism catabolic process GO:0044712 129 0.010
cytokinesis GO:0000910 80 0.010
negative regulation of cellular process GO:0048523 239 0.010
single organism cellular localization GO:1902580 72 0.010
organic cyclic compound biosynthetic process GO:1901362 195 0.010
regulation of biosynthetic process GO:0009889 189 0.010
intracellular signal transduction GO:0035556 96 0.010
embryonic morphogenesis GO:0048598 152 0.010
tissue morphogenesis GO:0048729 65 0.010

sphk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.012