Caenorhabditis elegans

10 known processes

fkb-3 (CELE_C05C8.3)

Protein FKB-3

fkb-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ development GO:0048513 1102 0.342
post embryonic development GO:0009791 2152 0.234
gonad development GO:0008406 840 0.194
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.176
determination of adult lifespan GO:0008340 812 0.174
aging GO:0007568 812 0.167
embryo development ending in birth or egg hatching GO:0009792 2992 0.162
er nucleus signaling pathway GO:0006984 66 0.148
oviposition GO:0018991 364 0.142
multicellular organismal aging GO:0010259 812 0.135
regulation of developmental process GO:0050793 684 0.132
reproductive behavior GO:0019098 387 0.122
biosynthetic process GO:0009058 323 0.122
digestive tract morphogenesis GO:0048546 76 0.113
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.112
sex differentiation GO:0007548 909 0.110
cellular response to chemical stimulus GO:0070887 129 0.094
cellular component morphogenesis GO:0032989 318 0.092
regulation of developmental growth GO:0048638 389 0.090
reproductive structure development GO:0048608 850 0.087
multicellular organism reproduction GO:0032504 819 0.087
locomotion GO:0040011 1634 0.084
embryo development GO:0009790 3052 0.083
nuclear pore localization GO:0051664 2 0.082
reproductive system development GO:0061458 850 0.080
multi organism reproductive behavior GO:0044705 387 0.079
apoptotic process GO:0006915 478 0.076
cellular component assembly involved in morphogenesis GO:0010927 183 0.074
multi organism reproductive process GO:0044703 867 0.073
cell death GO:0008219 547 0.073
multi organism behavior GO:0051705 389 0.073
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.071
genitalia development GO:0048806 741 0.070
multi multicellular organism process GO:0044706 390 0.070
cell development GO:0048468 696 0.070
developmental process involved in reproduction GO:0003006 1165 0.067
maintenance of location GO:0051235 580 0.066
multicellular organismal reproductive process GO:0048609 815 0.065
macromolecule localization GO:0033036 771 0.065
nucleobase containing compound metabolic process GO:0006139 406 0.065
development of primary sexual characteristics GO:0045137 840 0.065
programmed cell death GO:0012501 500 0.064
organelle organization GO:0006996 783 0.063
lipid localization GO:0010876 573 0.062
multicellular organismal reproductive behavior GO:0033057 384 0.060
cell migration GO:0016477 306 0.059
macromolecular complex subunit organization GO:0043933 320 0.058
germ cell development GO:0007281 351 0.057
regulation of growth GO:0040008 409 0.056
cellular component movement GO:0006928 388 0.055
lipid storage GO:0019915 565 0.054
death GO:0016265 547 0.050
single organism reproductive process GO:0044702 1196 0.050
cytoskeleton organization GO:0007010 339 0.048
developmental growth GO:0048589 412 0.047
digestive system development GO:0055123 122 0.046
behavior GO:0007610 527 0.045
single organism organelle organization GO:1902589 501 0.044
regulation of gene expression GO:0010468 366 0.044
muscle structure development GO:0061061 191 0.043
positive regulation of rna metabolic process GO:0051254 103 0.043
positive regulation of multicellular organismal process GO:0051240 417 0.043
positive regulation of cellular process GO:0048522 332 0.041
myofibril assembly GO:0030239 154 0.041
multicellular organism growth GO:0035264 385 0.040
organelle fission GO:0048285 363 0.040
response to chemical GO:0042221 356 0.040
regulation of biological quality GO:0065008 741 0.040
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.038
muscle cell development GO:0055001 158 0.038
cellular biosynthetic process GO:0044249 315 0.038
muscle cell differentiation GO:0042692 171 0.037
striated muscle cell development GO:0055002 157 0.037
regulation of multicellular organism growth GO:0040014 373 0.037
mitotic nuclear envelope reassembly GO:0007084 3 0.036
growth GO:0040007 562 0.036
cellular macromolecule biosynthetic process GO:0034645 247 0.036
cell motility GO:0048870 313 0.035
molting cycle GO:0042303 281 0.035
epithelial cell proliferation GO:0050673 1 0.034
organic substance biosynthetic process GO:1901576 323 0.034
positive regulation of developmental process GO:0051094 408 0.034
regulation of cell death GO:0010941 65 0.034
establishment or maintenance of cell polarity GO:0007163 63 0.034
signal transduction GO:0007165 317 0.033
cell surface receptor signaling pathway GO:0007166 149 0.032
macromolecule biosynthetic process GO:0009059 250 0.031
regulation of multicellular organismal development GO:2000026 317 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.030
actomyosin structure organization GO:0031032 154 0.030
cellular nitrogen compound biosynthetic process GO:0044271 192 0.030
hermaphrodite genitalia development GO:0040035 734 0.030
protein complex subunit organization GO:0071822 280 0.030
regulation of multicellular organismal process GO:0051239 726 0.029
macromolecule catabolic process GO:0009057 202 0.029
organic cyclic compound biosynthetic process GO:1901362 195 0.028
regulation of organelle organization GO:0033043 164 0.028
rna biosynthetic process GO:0032774 169 0.028
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.028
localization of cell GO:0051674 313 0.028
transcription from rna polymerase ii promoter GO:0006366 149 0.027
regulation of nitrogen compound metabolic process GO:0051171 222 0.027
positive regulation of transcription dna templated GO:0045893 102 0.027
positive regulation of developmental growth GO:0048639 354 0.027
negative regulation of gene expression GO:0010629 217 0.026
single organism signaling GO:0044700 401 0.025
regulation of macromolecule metabolic process GO:0060255 421 0.025
cellular response to stress GO:0033554 162 0.025
regulation of locomotion GO:0040012 161 0.025
regulation of metabolic process GO:0019222 478 0.025
cellular response to topologically incorrect protein GO:0035967 76 0.024
regulation of cell migration GO:0030334 55 0.024
peptidyl proline hydroxylation to 4 hydroxy l proline GO:0018401 3 0.024
positive regulation of cellular biosynthetic process GO:0031328 109 0.023
response to abiotic stimulus GO:0009628 152 0.022
striated muscle myosin thick filament assembly GO:0071688 138 0.022
nucleic acid metabolic process GO:0090304 299 0.022
cellular component biogenesis GO:0044085 297 0.022
positive regulation of rna biosynthetic process GO:1902680 102 0.022
small molecule metabolic process GO:0044281 186 0.022
cellular response to organic substance GO:0071310 119 0.022
positive regulation of biosynthetic process GO:0009891 109 0.022
striated muscle cell differentiation GO:0051146 158 0.022
male sex differentiation GO:0046661 86 0.021
cellular macromolecular complex assembly GO:0034622 184 0.020
macromolecular complex assembly GO:0065003 193 0.020
nuclear pore distribution GO:0031081 2 0.020
vulval development GO:0040025 333 0.020
positive regulation of multicellular organism growth GO:0040018 352 0.020
aromatic compound biosynthetic process GO:0019438 192 0.020
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
myosin filament organization GO:0031033 138 0.019
regulation of epithelial cell proliferation GO:0050678 1 0.019
regulation of apoptotic signaling pathway GO:2001233 1 0.019
head development GO:0060322 1 0.019
cellular protein metabolic process GO:0044267 279 0.019
Mouse
regulation of programmed cell death GO:0043067 50 0.019
protein metabolic process GO:0019538 422 0.018
Mouse
regulation of macromolecule biosynthetic process GO:0010556 189 0.018
body morphogenesis GO:0010171 620 0.018
regulation of gene expression epigenetic GO:0040029 163 0.018
myosin filament assembly GO:0031034 138 0.018
negative regulation of biological process GO:0048519 567 0.017
regulation of vulval development GO:0040028 248 0.017
cell division GO:0051301 262 0.017
negative regulation of developmental process GO:0051093 227 0.017
gene expression GO:0010467 412 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.017
gene silencing GO:0016458 143 0.016
immune response GO:0006955 192 0.016
negative regulation of metabolic process GO:0009892 240 0.016
nucleic acid templated transcription GO:0097659 169 0.016
catabolic process GO:0009056 318 0.016
nucleobase containing compound biosynthetic process GO:0034654 184 0.016
organelle assembly GO:0070925 214 0.016
vesicle mediated transport GO:0016192 852 0.015
defense response GO:0006952 296 0.015
protein homooligomerization GO:0051260 3 0.015
regulation of biosynthetic process GO:0009889 189 0.015
actin filament based process GO:0030029 191 0.015
cellular amino acid metabolic process GO:0006520 15 0.015
cellular component assembly GO:0022607 293 0.015
positive regulation of growth GO:0045927 369 0.015
organonitrogen compound metabolic process GO:1901564 151 0.015
protein complex assembly GO:0006461 186 0.015
regulation of response to stimulus GO:0048583 243 0.015
cell proliferation GO:0008283 116 0.015
nervous system development GO:0007399 253 0.014
regulation of apoptotic process GO:0042981 36 0.014
carboxylic acid metabolic process GO:0019752 34 0.014
muscle organ morphogenesis GO:0048644 4 0.014
cell part morphogenesis GO:0032990 152 0.014
organic substance catabolic process GO:1901575 294 0.014
actin cytoskeleton organization GO:0030036 184 0.013
regulation of gene silencing GO:0060968 3 0.013
positive regulation of gene expression GO:0010628 112 0.013
oogenesis GO:0048477 229 0.013
organic acid metabolic process GO:0006082 47 0.013
protein catabolic process GO:0030163 162 0.013
phosphate containing compound metabolic process GO:0006796 232 0.013
cellular nitrogen compound catabolic process GO:0044270 119 0.013
digestive tract development GO:0048565 122 0.013
regulation of transcription dna templated GO:0006355 164 0.013
negative regulation of signaling GO:0023057 61 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.013
regulation of cell motility GO:2000145 57 0.013
regulation of cell proliferation GO:0042127 105 0.012
defense response to other organism GO:0098542 100 0.012
gamete generation GO:0007276 461 0.012
response to bacterium GO:0009617 86 0.012
negative regulation of signal transduction GO:0009968 60 0.012
cellular protein complex localization GO:0034629 3 0.012
axonogenesis GO:0007409 102 0.012
signaling GO:0023052 401 0.012
regulation of rna metabolic process GO:0051252 173 0.012
protein polymerization GO:0051258 26 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.012
post embryonic organ development GO:0048569 336 0.012
regulation of anatomical structure morphogenesis GO:0022603 51 0.012
receptor mediated endocytosis GO:0006898 715 0.012
male anatomical structure morphogenesis GO:0090598 78 0.012
negative regulation of gene expression epigenetic GO:0045814 2 0.011
response to wounding GO:0009611 4 0.011
cellular protein complex assembly GO:0043623 178 0.011
protein localization GO:0008104 205 0.011
response to biotic stimulus GO:0009607 101 0.011
sexual reproduction GO:0019953 546 0.011
secretion GO:0046903 147 0.011
regulation of anatomical structure size GO:0090066 46 0.011
chromosome segregation GO:0007059 180 0.010
nucleus organization GO:0006997 38 0.010
regulation of cellular biosynthetic process GO:0031326 189 0.010

fkb-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.116
muscular disease DOID:0080000 0 0.116
heart disease DOID:114 0 0.116
cardiomyopathy DOID:0050700 0 0.116
disease of anatomical entity DOID:7 0 0.116
cardiovascular system disease DOID:1287 0 0.116
musculoskeletal system disease DOID:17 0 0.116
muscle tissue disease DOID:66 0 0.116
muscular dystrophy DOID:9884 0 0.086
limb girdle muscular dystrophy DOID:11724 0 0.086
lipodystrophy DOID:811 0 0.027
skin disease DOID:37 0 0.027
integumentary system disease DOID:16 0 0.027
familial partial lipodystrophy DOID:0050440 0 0.027
dilated cardiomyopathy DOID:12930 0 0.020
intrinsic cardiomyopathy DOID:0060036 0 0.020
congenital muscular dystrophy DOID:0050557 0 0.010