Caenorhabditis elegans

83 known processes

sma-4 (CELE_R12B2.1)

Protein SMA-4

sma-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
male sex differentiation GO:0046661 86 0.279
establishment of localization GO:0051234 1171 0.257
Mouse
gonad development GO:0008406 840 0.230
positive regulation of multicellular organismal process GO:0051240 417 0.230
sex differentiation GO:0007548 909 0.190
cell surface receptor signaling pathway GO:0007166 149 0.178
Human Mouse Fly
single organism transport GO:0044765 447 0.160
Mouse
innate immune response GO:0045087 190 0.159
Worm
reproductive structure development GO:0048608 850 0.149
behavior GO:0007610 527 0.148
Worm
signaling GO:0023052 401 0.144
Human Mouse Worm Fly
aging GO:0007568 812 0.138
locomotion GO:0040011 1634 0.138
organ development GO:0048513 1102 0.136
single organism localization GO:1902578 518 0.131
Mouse
response to chemical GO:0042221 356 0.127
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 421 0.124
regulation of biological quality GO:0065008 741 0.121
neurogenesis GO:0022008 236 0.119
Mouse Fly
single organism reproductive process GO:0044702 1196 0.116
Fly
response to external stimulus GO:0009605 289 0.113
Mouse Worm Fly
regulation of cellular metabolic process GO:0031323 305 0.111
Human Mouse Worm
cation transport GO:0006812 78 0.110
negative regulation of biological process GO:0048519 567 0.104
multi organism behavior GO:0051705 389 0.104
Worm
regulation of multicellular organismal process GO:0051239 726 0.103
defense response to bacterium GO:0042742 86 0.099
Worm
catabolic process GO:0009056 318 0.098
response to organic substance GO:0010033 131 0.095
Human Mouse Fly
cellular response to organic substance GO:0071310 119 0.095
Human Mouse Fly
positive regulation of rna biosynthetic process GO:1902680 102 0.090
Human Mouse Worm
receptor mediated endocytosis GO:0006898 715 0.090
nematode male tail tip morphogenesis GO:0045138 77 0.088
positive regulation of growth GO:0045927 369 0.086
response to endogenous stimulus GO:0009719 33 0.084
Human Mouse Fly
positive regulation of developmental growth GO:0048639 354 0.082
transport GO:0006810 1093 0.080
Mouse
developmental growth GO:0048589 412 0.079
organic substance biosynthetic process GO:1901576 323 0.077
Human Mouse Worm
positive regulation of gene expression GO:0010628 112 0.076
Human Mouse Worm
intracellular signal transduction GO:0035556 96 0.075
Human Worm
macromolecule localization GO:0033036 771 0.073
Mouse
phagocytosis GO:0006909 115 0.072
nucleobase containing compound metabolic process GO:0006139 406 0.072
Human Mouse Worm
reproductive system development GO:0061458 850 0.071
small molecule metabolic process GO:0044281 186 0.071
multicellular organismal reproductive behavior GO:0033057 384 0.070
Worm
growth GO:0040007 562 0.069
organonitrogen compound metabolic process GO:1901564 151 0.069
negative regulation of macromolecule metabolic process GO:0010605 229 0.069
Human Worm
single organism signaling GO:0044700 401 0.069
Human Mouse Worm Fly
lipid storage GO:0019915 565 0.067
positive regulation of developmental process GO:0051094 408 0.067
signal transduction GO:0007165 317 0.064
Human Mouse Worm Fly
regulation of multicellular organism growth GO:0040014 373 0.063
neuron projection development GO:0031175 187 0.062
Mouse Fly
positive regulation of multicellular organism growth GO:0040018 352 0.060
regulation of developmental process GO:0050793 684 0.060
neuron differentiation GO:0030182 217 0.058
Mouse Fly
cellular protein metabolic process GO:0044267 279 0.056
Mouse
cell fate commitment GO:0045165 139 0.056
Mouse
development of primary sexual characteristics GO:0045137 840 0.054
multicellular organismal aging GO:0010259 812 0.053
protein metabolic process GO:0019538 422 0.052
lipid localization GO:0010876 573 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.051
Human Mouse Worm
organic substance catabolic process GO:1901575 294 0.050
hermaphrodite genitalia development GO:0040035 734 0.050
regulation of signaling GO:0023051 172 0.050
Human Mouse
developmental process involved in reproduction GO:0003006 1165 0.048
phosphorus metabolic process GO:0006793 232 0.047
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.046
Human Mouse Worm
maintenance of location GO:0051235 580 0.045
response to other organism GO:0051707 101 0.044
Worm
generation of neurons GO:0048699 235 0.044
Mouse Fly
determination of adult lifespan GO:0008340 812 0.043
multicellular organismal reproductive process GO:0048609 815 0.042
Worm Fly
post embryonic development GO:0009791 2152 0.041
death GO:0016265 547 0.041
Mouse
transcription from rna polymerase ii promoter GO:0006366 149 0.041
Human Mouse Worm
programmed cell death GO:0012501 500 0.040
positive regulation of signal transduction GO:0009967 40 0.039
Human Mouse
regulation of cell communication GO:0010646 176 0.039
Human Mouse
regulation of metabolic process GO:0019222 478 0.039
reproductive behavior GO:0019098 387 0.039
Worm
regulation of cell proliferation GO:0042127 105 0.039
Mouse
localization of cell GO:0051674 313 0.038
negative regulation of cellular process GO:0048523 239 0.038
Human Mouse Worm Fly
cell motility GO:0048870 313 0.038
head development GO:0060322 1 0.037
oviposition GO:0018991 364 0.036
Worm
regulation of growth GO:0040008 409 0.035
embryo development ending in birth or egg hatching GO:0009792 2992 0.034
Mouse
epithelial cell proliferation GO:0050673 1 0.034
cellular biosynthetic process GO:0044249 315 0.034
Human Mouse Worm
genitalia development GO:0048806 741 0.034
multi organism reproductive behavior GO:0044705 387 0.034
Worm
regulation of signal transduction GO:0009966 135 0.033
Human Mouse
multi multicellular organism process GO:0044706 390 0.033
Worm
endocytosis GO:0006897 819 0.033
regulation of cellular component organization GO:0051128 248 0.033
Human Mouse Fly
positive regulation of epithelial cell proliferation GO:0050679 1 0.033
cellular macromolecule biosynthetic process GO:0034645 247 0.031
Human Mouse Worm
establishment of localization in cell GO:0051649 318 0.030
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.030
Human Worm
gene expression GO:0010467 412 0.030
Human Mouse Worm
negative regulation of metabolic process GO:0009892 240 0.029
Human Worm
cellular protein modification process GO:0006464 207 0.029
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 102 0.029
Human Mouse Worm
defense response to gram negative bacterium GO:0050829 64 0.029
Worm
cellular catabolic process GO:0044248 199 0.029
intraspecies interaction between organisms GO:0051703 3 0.028
Worm
positive regulation of cellular process GO:0048522 332 0.027
Human Mouse Worm Fly
cellular localization GO:0051641 360 0.027
Mouse
macromolecule catabolic process GO:0009057 202 0.027
regulation of anatomical structure size GO:0090066 46 0.027
transcription dna templated GO:0006351 168 0.026
Human Mouse Worm
vesicle mediated transport GO:0016192 852 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.026
Human Mouse Worm
multicellular organism reproduction GO:0032504 819 0.025
Worm Fly
regulation of phosphate metabolic process GO:0019220 81 0.025
Mouse
cellular component movement GO:0006928 388 0.024
Mouse Fly
carboxylic acid metabolic process GO:0019752 34 0.024
mapk cascade GO:0000165 31 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.024
Human Mouse Worm
regulation of cell morphogenesis GO:0022604 40 0.024
Mouse
regulation of epithelial cell proliferation GO:0050678 1 0.024
organic acid metabolic process GO:0006082 47 0.024
multi organism reproductive process GO:0044703 867 0.023
Worm Fly
response to wounding GO:0009611 4 0.023
positive regulation of organ growth GO:0046622 4 0.023
cell projection organization GO:0030030 231 0.022
Mouse Fly
embryo development GO:0009790 3052 0.022
Mouse
ribonucleotide catabolic process GO:0009261 75 0.022
multicellular organism growth GO:0035264 385 0.022
regulation of lipid biosynthetic process GO:0046890 1 0.022
nucleotide metabolic process GO:0009117 108 0.022
single organism catabolic process GO:0044712 129 0.021
cellular response to chemical stimulus GO:0070887 129 0.021
Human Mouse Fly
ion transport GO:0006811 113 0.021
defense response GO:0006952 296 0.021
Worm
male anatomical structure morphogenesis GO:0090598 78 0.021
lipid metabolic process GO:0006629 77 0.020
cell death GO:0008219 547 0.020
Mouse
canonical wnt signaling pathway GO:0060070 3 0.020
ribonucleoside triphosphate catabolic process GO:0009203 72 0.020
regulation of multicellular organismal development GO:2000026 317 0.020
response to bacterium GO:0009617 86 0.020
Worm
cell proliferation GO:0008283 116 0.020
Mouse Fly
regulation of cellular protein metabolic process GO:0032268 75 0.020
Mouse
positive regulation of macromolecule metabolic process GO:0010604 149 0.020
cell migration GO:0016477 306 0.019
protein localization GO:0008104 205 0.019
Mouse
positive regulation of cell communication GO:0010647 69 0.019
Human Mouse
cellular amine metabolic process GO:0044106 15 0.019
cellular component biogenesis GO:0044085 297 0.019
Human Fly
regulation of intracellular signal transduction GO:1902531 77 0.019
biosynthetic process GO:0009058 323 0.018
Human Mouse Worm
molting cycle GO:0042303 281 0.018
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.018
cell part morphogenesis GO:0032990 152 0.018
Mouse Fly
dna modification GO:0006304 2 0.017
macromolecule modification GO:0043412 218 0.017
Mouse
positive regulation of biosynthetic process GO:0009891 109 0.017
Human Mouse Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.017
Human Mouse Worm
amine metabolic process GO:0009308 15 0.017
posttranscriptional regulation of gene expression GO:0010608 166 0.017
collagen and cuticulin based cuticle development GO:0040002 99 0.017
nucleic acid metabolic process GO:0090304 299 0.017
Human Mouse Worm
nervous system development GO:0007399 253 0.016
Mouse Fly
regulation of primary metabolic process GO:0080090 292 0.016
gene silencing by rna GO:0031047 143 0.016
post embryonic organ development GO:0048569 336 0.016
regulation of cellular biosynthetic process GO:0031326 189 0.016
Human Mouse Worm
organophosphate metabolic process GO:0019637 125 0.016
cell recognition GO:0008037 85 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
Mouse
lipid biosynthetic process GO:0008610 28 0.015
regulation of transcription dna templated GO:0006355 164 0.015
Human Mouse Worm
negative regulation of mitotic cell cycle GO:0045930 42 0.015
Worm
carbohydrate derivative catabolic process GO:1901136 82 0.015
ribonucleoside catabolic process GO:0042454 77 0.015
carbohydrate derivative metabolic process GO:1901135 141 0.015
positive regulation of metabolic process GO:0009893 187 0.014
regulation of macromolecule biosynthetic process GO:0010556 189 0.014
Human Mouse Worm
positive regulation of cellular biosynthetic process GO:0031328 109 0.014
Human Mouse Worm
cuticle development GO:0042335 100 0.014
membrane organization GO:0061024 135 0.014
defense response to other organism GO:0098542 100 0.014
Worm
regulation of developmental growth GO:0048638 389 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.013
cell type specific apoptotic process GO:0097285 4 0.013
regulation of protein targeting GO:1903533 3 0.012
Mouse
axis specification GO:0009798 23 0.012
Mouse Fly
body morphogenesis GO:0010171 620 0.012
nucleoside phosphate metabolic process GO:0006753 108 0.012
negative regulation of nematode larval development GO:0061064 208 0.012
purine ribonucleotide metabolic process GO:0009150 95 0.012
oxoacid metabolic process GO:0043436 47 0.012
adult locomotory behavior GO:0008344 1 0.012
apoptotic process GO:0006915 478 0.012
carbohydrate metabolic process GO:0005975 34 0.012
neuromuscular junction development GO:0007528 2 0.012
Fly
cellular response to endogenous stimulus GO:0071495 32 0.012
Human Mouse Fly
response to abiotic stimulus GO:0009628 152 0.012
Human
negative regulation of neurogenesis GO:0050768 4 0.012
negative regulation of transcription dna templated GO:0045892 53 0.011
Human Worm
cell projection morphogenesis GO:0048858 148 0.011
Mouse Fly
nucleoside phosphate catabolic process GO:1901292 77 0.011
response to biotic stimulus GO:0009607 101 0.011
Worm
regulation of apoptotic signaling pathway GO:2001233 1 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
Fly
gtp catabolic process GO:0006184 46 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.011
Human Mouse Worm
posttranscriptional gene silencing by rna GO:0035194 143 0.011
purine nucleoside catabolic process GO:0006152 75 0.011
posttranscriptional gene silencing GO:0016441 143 0.011
ribose phosphate metabolic process GO:0019693 99 0.011
digestive tract development GO:0048565 122 0.011
Mouse
negative regulation of vulval development GO:0040027 206 0.011
regulation of hydrolase activity GO:0051336 45 0.011
response to growth factor GO:0070848 18 0.010
Human Mouse Fly
protein modification process GO:0036211 207 0.010
Mouse
apoptotic cell clearance GO:0043277 111 0.010
organophosphate catabolic process GO:0046434 81 0.010
neuron development GO:0048666 199 0.010
Mouse Fly
regulation of post embryonic development GO:0048580 260 0.010

sma-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org