Caenorhabditis elegans

11 known processes

hlh-27 (CELE_C17C3.10)

Protein HLH-27

hlh-27 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 852 0.312
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.295
sex differentiation GO:0007548 909 0.291
Worm
developmental process involved in reproduction GO:0003006 1165 0.244
Worm
embryo development GO:0009790 3052 0.238
development of primary sexual characteristics GO:0045137 840 0.224
Worm
post embryonic development GO:0009791 2152 0.203
Worm
transport GO:0006810 1093 0.203
Worm
single organism reproductive process GO:0044702 1196 0.201
Worm
reproductive structure development GO:0048608 850 0.195
Worm
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.191
endocytosis GO:0006897 819 0.191
Worm
locomotion GO:0040011 1634 0.189
establishment of localization GO:0051234 1171 0.185
Worm
reproductive system development GO:0061458 850 0.180
Worm
oviposition GO:0018991 364 0.172
Worm
vulval development GO:0040025 333 0.165
Worm
receptor mediated endocytosis GO:0006898 715 0.164
Worm
genitalia development GO:0048806 741 0.154
Worm
gonad development GO:0008406 840 0.139
Worm
axonogenesis GO:0007409 102 0.133
multicellular organismal reproductive process GO:0048609 815 0.129
Worm
organ development GO:0048513 1102 0.125
Worm
regulation of primary metabolic process GO:0080090 292 0.124
cellular component movement GO:0006928 388 0.123
gene expression GO:0010467 412 0.117
body morphogenesis GO:0010171 620 0.117
hermaphrodite genitalia development GO:0040035 734 0.117
Worm
regulation of biological quality GO:0065008 741 0.115
Worm
regulation of developmental process GO:0050793 684 0.108
regulation of macromolecule metabolic process GO:0060255 421 0.107
reproductive behavior GO:0019098 387 0.105
Worm
regulation of multicellular organismal process GO:0051239 726 0.102
transcription dna templated GO:0006351 168 0.101
regulation of metabolic process GO:0019222 478 0.099
organelle organization GO:0006996 783 0.098
cell death GO:0008219 547 0.098
cellular macromolecule biosynthetic process GO:0034645 247 0.096
regulation of nitrogen compound metabolic process GO:0051171 222 0.096
negative regulation of metabolic process GO:0009892 240 0.095
behavior GO:0007610 527 0.095
Worm
negative regulation of gene expression GO:0010629 217 0.094
regulation of rna metabolic process GO:0051252 173 0.093
macromolecule localization GO:0033036 771 0.093
Worm
neuron projection morphogenesis GO:0048812 114 0.091
multicellular organismal aging GO:0010259 812 0.090
multicellular organism reproduction GO:0032504 819 0.088
Worm
negative regulation of transcription dna templated GO:0045892 53 0.087
negative regulation of biological process GO:0048519 567 0.087
rna metabolic process GO:0016070 228 0.086
neuron differentiation GO:0030182 217 0.086
multi organism reproductive process GO:0044703 867 0.086
Worm
axon development GO:0061564 163 0.085
multi multicellular organism process GO:0044706 390 0.084
Worm
cell part morphogenesis GO:0032990 152 0.081
multi organism behavior GO:0051705 389 0.080
Worm
aging GO:0007568 812 0.079
cell projection morphogenesis GO:0048858 148 0.079
determination of adult lifespan GO:0008340 812 0.077
aromatic compound biosynthetic process GO:0019438 192 0.076
cell development GO:0048468 696 0.076
nucleic acid metabolic process GO:0090304 299 0.076
nucleobase containing compound metabolic process GO:0006139 406 0.076
regulation of gene expression GO:0010468 366 0.076
generation of neurons GO:0048699 235 0.076
growth GO:0040007 562 0.074
cell motility GO:0048870 313 0.074
maintenance of location GO:0051235 580 0.074
Worm
regulation of macromolecule biosynthetic process GO:0010556 189 0.073
head development GO:0060322 1 0.073
multi organism reproductive behavior GO:0044705 387 0.073
Worm
neuron development GO:0048666 199 0.071
regulation of rna biosynthetic process GO:2001141 165 0.070
programmed cell death GO:0012501 500 0.070
post embryonic organ development GO:0048569 336 0.070
Worm
cell migration GO:0016477 306 0.069
lipid localization GO:0010876 573 0.069
Worm
neurogenesis GO:0022008 236 0.069
cellular component morphogenesis GO:0032989 318 0.067
regulation of cellular metabolic process GO:0031323 305 0.067
regulation of nucleic acid templated transcription GO:1903506 165 0.067
positive regulation of multicellular organismal process GO:0051240 417 0.065
localization of cell GO:0051674 313 0.065
developmental growth GO:0048589 412 0.064
anatomical structure formation involved in morphogenesis GO:0048646 250 0.064
multicellular organismal reproductive behavior GO:0033057 384 0.063
Worm
neuron projection development GO:0031175 187 0.062
cell morphogenesis GO:0000902 163 0.062
lipid storage GO:0019915 565 0.062
Worm
regulation of transcription dna templated GO:0006355 164 0.062
apoptotic process GO:0006915 478 0.060
organic substance biosynthetic process GO:1901576 323 0.059
biosynthetic process GO:0009058 323 0.058
negative regulation of macromolecule metabolic process GO:0010605 229 0.057
response to chemical GO:0042221 356 0.057
Worm
cell projection organization GO:0030030 231 0.057
death GO:0016265 547 0.055
cell morphogenesis involved in differentiation GO:0000904 112 0.055
regulation of growth GO:0040008 409 0.054
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.053
regulation of developmental growth GO:0048638 389 0.053
negative regulation of nucleic acid templated transcription GO:1903507 53 0.052
developmental growth involved in morphogenesis GO:0060560 37 0.052
negative regulation of biosynthetic process GO:0009890 65 0.052
positive regulation of rna biosynthetic process GO:1902680 102 0.052
rna biosynthetic process GO:0032774 169 0.052
macromolecule biosynthetic process GO:0009059 250 0.052
nucleobase containing compound biosynthetic process GO:0034654 184 0.051
positive regulation of nucleic acid templated transcription GO:1903508 102 0.051
signaling GO:0023052 401 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.050
regulation of multicellular organismal development GO:2000026 317 0.049
positive regulation of cellular process GO:0048522 332 0.049
cellular biosynthetic process GO:0044249 315 0.049
transcription from rna polymerase ii promoter GO:0006366 149 0.049
cellular protein metabolic process GO:0044267 279 0.049
positive regulation of multicellular organism growth GO:0040018 352 0.049
response to external stimulus GO:0009605 289 0.049
single organism localization GO:1902578 518 0.048
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.048
neuron projection guidance GO:0097485 82 0.048
positive regulation of rna metabolic process GO:0051254 103 0.048
positive regulation of growth GO:0045927 369 0.047
cellular nitrogen compound biosynthetic process GO:0044271 192 0.047
regulation of nematode larval development GO:0061062 260 0.047
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.047
positive regulation of developmental process GO:0051094 408 0.046
regulation of cellular biosynthetic process GO:0031326 189 0.046
organic cyclic compound biosynthetic process GO:1901362 195 0.046
nervous system development GO:0007399 253 0.046
positive regulation of developmental growth GO:0048639 354 0.045
negative regulation of cellular metabolic process GO:0031324 95 0.045
positive regulation of macromolecule metabolic process GO:0010604 149 0.044
cell fate commitment GO:0045165 139 0.044
cytoskeleton organization GO:0007010 339 0.044
multicellular organism growth GO:0035264 385 0.043
negative regulation of rna biosynthetic process GO:1902679 53 0.043
mesoderm morphogenesis GO:0048332 24 0.043
heterocycle biosynthetic process GO:0018130 187 0.042
regulation of post embryonic development GO:0048580 260 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.042
regulation of biosynthetic process GO:0009889 189 0.041
chemotaxis GO:0006935 120 0.041
single organism organelle organization GO:1902589 501 0.041
gamete generation GO:0007276 461 0.041
negative regulation of cellular biosynthetic process GO:0031327 65 0.040
regulation of vulval development GO:0040028 248 0.040
organelle assembly GO:0070925 214 0.039
negative regulation of cellular process GO:0048523 239 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.039
posttranscriptional regulation of gene expression GO:0010608 166 0.039
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.038
positive regulation of gene expression GO:0010628 112 0.038
positive regulation of cellular biosynthetic process GO:0031328 109 0.038
response to wounding GO:0009611 4 0.037
regulation of multicellular organism growth GO:0040014 373 0.037
protein metabolic process GO:0019538 422 0.037
cell type specific apoptotic process GO:0097285 4 0.036
negative regulation of nematode larval development GO:0061064 208 0.036
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.036
negative regulation of vulval development GO:0040027 206 0.035
nucleic acid templated transcription GO:0097659 169 0.035
axon guidance GO:0007411 82 0.035
positive regulation of transcription dna templated GO:0045893 102 0.035
positive regulation of biosynthetic process GO:0009891 109 0.035
cellular component assembly GO:0022607 293 0.035
macromolecular complex subunit organization GO:0043933 320 0.034
positive regulation of metabolic process GO:0009893 187 0.034
negative regulation of developmental process GO:0051093 227 0.034
cell cycle process GO:0022402 482 0.034
germ cell development GO:0007281 351 0.034
molting cycle GO:0042303 281 0.033
gene silencing GO:0016458 143 0.033
nematode male tail tip morphogenesis GO:0045138 77 0.033
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.033
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.032
taxis GO:0042330 128 0.032
cellular component assembly involved in morphogenesis GO:0010927 183 0.032
male anatomical structure morphogenesis GO:0090598 78 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.032
sexual reproduction GO:0019953 546 0.031
single organism signaling GO:0044700 401 0.031
axon extension GO:0048675 37 0.031
negative regulation of post embryonic development GO:0048581 208 0.031
cellular component biogenesis GO:0044085 297 0.030
protein localization GO:0008104 205 0.030
single organism transport GO:0044765 447 0.028
female gamete generation GO:0007292 254 0.028
neuron projection extension GO:1990138 37 0.028
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.028
cellular localization GO:0051641 360 0.027
cell growth GO:0016049 44 0.027
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.027
cell cycle GO:0007049 526 0.027
regulation of cellular ketone metabolic process GO:0010565 3 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.027
regulation of gene expression epigenetic GO:0040029 163 0.026
muscle cell differentiation GO:0042692 171 0.026
negative regulation of multicellular organismal process GO:0051241 236 0.025
actin cytoskeleton organization GO:0030036 184 0.024
sensory organ morphogenesis GO:0090596 2 0.024
negative regulation of rna metabolic process GO:0051253 53 0.024
embryonic morphogenesis GO:0048598 152 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.024
oogenesis GO:0048477 229 0.024
defense response GO:0006952 296 0.024
inductive cell migration GO:0040039 145 0.024
cell fate specification involved in pattern specification GO:0060573 4 0.024
actin filament based process GO:0030029 191 0.024
regulation of response to stimulus GO:0048583 243 0.024
posttranscriptional gene silencing GO:0016441 143 0.024
regulation of cell communication GO:0010646 176 0.024
positive regulation of cellular metabolic process GO:0031325 178 0.023
signal transduction GO:0007165 317 0.023
protein complex subunit organization GO:0071822 280 0.022
cell cell signaling GO:0007267 118 0.022
tissue development GO:0009888 112 0.022
posttranscriptional gene silencing by rna GO:0035194 143 0.022
establishment of localization in cell GO:0051649 318 0.022
striated muscle cell differentiation GO:0051146 158 0.022
canonical wnt signaling pathway GO:0060070 3 0.021
regulation of localization GO:0032879 194 0.021
developmental cell growth GO:0048588 39 0.021
regulation of apoptotic signaling pathway GO:2001233 1 0.021
organic acid metabolic process GO:0006082 47 0.021
striated muscle cell development GO:0055002 157 0.021
collagen and cuticulin based cuticle development GO:0040002 99 0.021
translation GO:0006412 37 0.021
secretion GO:0046903 147 0.021
cell division GO:0051301 262 0.021
secretion by cell GO:0032940 138 0.021
small molecule metabolic process GO:0044281 186 0.020
regulation of cytoplasmic transport GO:1903649 3 0.020
oxoacid metabolic process GO:0043436 47 0.020
muscle structure development GO:0061061 191 0.020
muscle cell development GO:0055001 158 0.020
system process GO:0003008 136 0.020
digestive tract development GO:0048565 122 0.020
male sex differentiation GO:0046661 86 0.020
cell surface receptor signaling pathway GO:0007166 149 0.020
cellular protein complex assembly GO:0043623 178 0.020
digestive system development GO:0055123 122 0.020
positive regulation of vulval development GO:0040026 52 0.019
epithelial tube morphogenesis GO:0060562 1 0.019
epithelial cell proliferation GO:0050673 1 0.019
negative regulation of gene expression epigenetic GO:0045814 2 0.019
regulation of cellular component organization GO:0051128 248 0.019
muscle tissue development GO:0060537 1 0.019
immune response GO:0006955 192 0.019
cuticle development GO:0042335 100 0.019
organ morphogenesis GO:0009887 67 0.019
positive regulation of neurogenesis GO:0050769 4 0.019
striated muscle myosin thick filament assembly GO:0071688 138 0.019
catabolic process GO:0009056 318 0.018
regulation of cell differentiation GO:0045595 81 0.018
phagocytosis GO:0006909 115 0.018
myosin filament assembly GO:0031034 138 0.018
myofibril assembly GO:0030239 154 0.018
regulation of protein metabolic process GO:0051246 81 0.018
pattern specification process GO:0007389 59 0.018
microtubule based process GO:0007017 182 0.018
actomyosin structure organization GO:0031032 154 0.017
negative regulation of neurogenesis GO:0050768 4 0.017
myosin filament organization GO:0031033 138 0.017
regulation of signaling GO:0023051 172 0.017
neuron projection extension involved in neuron projection guidance GO:1902284 13 0.017
germ line sex determination GO:0018992 51 0.017
regulation of nucleocytoplasmic transport GO:0046822 3 0.017
single organism catabolic process GO:0044712 129 0.017
tube morphogenesis GO:0035239 79 0.017
hindgut development GO:0061525 3 0.016
macromolecule modification GO:0043412 218 0.016
lipid metabolic process GO:0006629 77 0.016
regulation of epithelial cell proliferation GO:0050678 1 0.016
regulation of lipid metabolic process GO:0019216 4 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
carboxylic acid metabolic process GO:0019752 34 0.016
positive regulation of intracellular transport GO:0032388 2 0.016
adult behavior GO:0030534 3 0.016
positive regulation of nematode larval development GO:0061063 54 0.015
macromolecular complex assembly GO:0065003 193 0.015
cellular ketone metabolic process GO:0042180 14 0.015
pharynx development GO:0060465 51 0.015
apoptotic cell clearance GO:0043277 111 0.015
meiotic cell cycle GO:0051321 335 0.015
rna interference GO:0016246 137 0.015
regulation of signal transduction GO:0009966 135 0.015
neurological system process GO:0050877 53 0.015
regeneration GO:0031099 4 0.014
membrane organization GO:0061024 135 0.014
digestive tract morphogenesis GO:0048546 76 0.014
protein complex assembly GO:0006461 186 0.014
organonitrogen compound metabolic process GO:1901564 151 0.014
spindle organization GO:0007051 92 0.014
dendrite development GO:0016358 42 0.014
pigmentation GO:0043473 2 0.014
chromosome organization GO:0051276 104 0.014
regulation of nervous system development GO:0051960 41 0.014
meiotic cell cycle process GO:1903046 170 0.014
regulation of neurogenesis GO:0050767 40 0.014
cellular response to chemical stimulus GO:0070887 129 0.014
organelle fission GO:0048285 363 0.014
rrna metabolic process GO:0016072 3 0.014
tube development GO:0035295 126 0.014
cellular macromolecular complex assembly GO:0034622 184 0.014
organism emergence from protective structure GO:0071684 48 0.014
Worm
neuromuscular junction development GO:0007528 2 0.014
regulation of cell death GO:0010941 65 0.014
positive regulation of cell migration GO:0030335 3 0.014
regulation of translation GO:0006417 19 0.013
positive regulation of post embryonic development GO:0048582 54 0.013
ribosome biogenesis GO:0042254 4 0.013
intracellular signal transduction GO:0035556 96 0.013
gene silencing by rna GO:0031047 143 0.013
regulation of programmed cell death GO:0043067 50 0.013
excretion GO:0007588 49 0.013
internal peptidyl lysine acetylation GO:0018393 3 0.013
cellular catabolic process GO:0044248 199 0.013
regulation of organelle organization GO:0033043 164 0.013
regulation of protein import into nucleus GO:0042306 3 0.013
protein complex biogenesis GO:0070271 186 0.013
cilium organization GO:0044782 32 0.013
regulation of cell division GO:0051302 142 0.013
cell projection assembly GO:0030031 35 0.013
organic substance transport GO:0071702 113 0.013
response to organic substance GO:0010033 131 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
mitotic cell cycle process GO:1903047 194 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
neuron apoptotic process GO:0051402 4 0.012
positive regulation of protein transport GO:0051222 4 0.012
skeletal muscle organ development GO:0060538 3 0.012
oocyte axis specification GO:0007309 2 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
cellular response to topologically incorrect protein GO:0035967 76 0.012
phagocytosis engulfment GO:0006911 98 0.012
response to biotic stimulus GO:0009607 101 0.012
regulation of response to wounding GO:1903034 1 0.012
rrna processing GO:0006364 3 0.012
oocyte construction GO:0007308 2 0.012
meiotic nuclear division GO:0007126 300 0.012
regulation of protein targeting GO:1903533 3 0.011
regulation of cell cycle GO:0051726 194 0.011
ribonucleoprotein complex assembly GO:0022618 4 0.011
cell proliferation GO:0008283 116 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
innate immune response GO:0045087 190 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
response to bacterium GO:0009617 86 0.011
axon extension involved in axon guidance GO:0048846 13 0.011
cellular response to organic substance GO:0071310 119 0.011
chromosome segregation GO:0007059 180 0.011
defense response to gram negative bacterium GO:0050829 64 0.011
ras protein signal transduction GO:0007265 31 0.011
regulation of nuclear division GO:0051783 115 0.011
phosphorus metabolic process GO:0006793 232 0.011
organelle localization GO:0051640 127 0.011
dauer larval development GO:0040024 92 0.011
embryonic body morphogenesis GO:0010172 49 0.011
autophagy GO:0006914 29 0.011
hormone transport GO:0009914 2 0.011
development of primary male sexual characteristics GO:0046546 4 0.011
amine metabolic process GO:0009308 15 0.011
cellular amine metabolic process GO:0044106 15 0.011
regulation of hormone secretion GO:0046883 2 0.011
defecation GO:0030421 47 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
phosphorylation GO:0016310 116 0.011
cellular protein modification process GO:0006464 207 0.011
defense response to bacterium GO:0042742 86 0.010
regulation of meiosis GO:0040020 94 0.010
axonal fasciculation GO:0007413 79 0.010
macromolecule catabolic process GO:0009057 202 0.010
mitotic spindle organization GO:0007052 81 0.010
chromatin assembly or disassembly GO:0006333 1 0.010
regulation of meiotic cell cycle GO:0051445 136 0.010
response to topologically incorrect protein GO:0035966 82 0.010
feeding behavior GO:0007631 70 0.010
engulfment of apoptotic cell GO:0043652 94 0.010
cellular response to stress GO:0033554 162 0.010
intracellular receptor signaling pathway GO:0030522 2 0.010
cilium morphogenesis GO:0060271 33 0.010
protein oligomerization GO:0051259 4 0.010
response to endoplasmic reticulum stress GO:0034976 71 0.010

hlh-27 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.010