Caenorhabditis elegans

60 known processes

tom-1 (CELE_M01A10.2)

Protein TOM-1

tom-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.201
embryo development ending in birth or egg hatching GO:0009792 2992 0.171
post embryonic development GO:0009791 2152 0.122
determination of adult lifespan GO:0008340 812 0.094
programmed cell death GO:0012501 500 0.091
death GO:0016265 547 0.089
cell death GO:0008219 547 0.086
endocytosis GO:0006897 819 0.086
apoptotic process GO:0006915 478 0.084
multicellular organismal aging GO:0010259 812 0.082
locomotion GO:0040011 1634 0.077
aging GO:0007568 812 0.076
transport GO:0006810 1093 0.074
regulation of biological quality GO:0065008 741 0.073
organelle organization GO:0006996 783 0.073
sexual reproduction GO:0019953 546 0.069
single organism localization GO:1902578 518 0.063
signaling GO:0023052 401 0.062
regulation of growth GO:0040008 409 0.061
macromolecule localization GO:0033036 771 0.060
positive regulation of growth GO:0045927 369 0.060
lipid localization GO:0010876 573 0.059
establishment of localization GO:0051234 1171 0.059
multicellular organism growth GO:0035264 385 0.058
regulation of multicellular organismal process GO:0051239 726 0.057
Human
developmental growth GO:0048589 412 0.057
lipid storage GO:0019915 565 0.057
regulation of developmental growth GO:0048638 389 0.054
maintenance of location GO:0051235 580 0.054
developmental process involved in reproduction GO:0003006 1165 0.052
vesicle mediated transport GO:0016192 852 0.052
cell development GO:0048468 696 0.051
nucleoside phosphate metabolic process GO:0006753 108 0.050
actomyosin structure organization GO:0031032 154 0.050
organophosphate metabolic process GO:0019637 125 0.049
oogenesis GO:0048477 229 0.049
multi organism reproductive process GO:0044703 867 0.048
organelle assembly GO:0070925 214 0.048
positive regulation of developmental growth GO:0048639 354 0.045
multicellular organism reproduction GO:0032504 819 0.045
regulation of macromolecule metabolic process GO:0060255 421 0.044
Human
post embryonic organ development GO:0048569 336 0.044
regulation of multicellular organism growth GO:0040014 373 0.042
negative regulation of biological process GO:0048519 567 0.041
multicellular organismal reproductive process GO:0048609 815 0.041
multicellular organismal reproductive behavior GO:0033057 384 0.040
positive regulation of multicellular organismal process GO:0051240 417 0.039
multi multicellular organism process GO:0044706 390 0.038
ion transport GO:0006811 113 0.037
positive regulation of gtpase activity GO:0043547 28 0.036
regulation of cellular metabolic process GO:0031323 305 0.036
signal transduction GO:0007165 317 0.035
cellular component assembly GO:0022607 293 0.034
behavior GO:0007610 527 0.034
myofibril assembly GO:0030239 154 0.034
positive regulation of multicellular organism growth GO:0040018 352 0.033
actin cytoskeleton organization GO:0030036 184 0.032
organ development GO:0048513 1102 0.032
cytoskeleton organization GO:0007010 339 0.032
nucleobase containing small molecule metabolic process GO:0055086 115 0.032
cellular component assembly involved in morphogenesis GO:0010927 183 0.032
reproductive behavior GO:0019098 387 0.030
phosphate containing compound metabolic process GO:0006796 232 0.030
ribonucleotide metabolic process GO:0009259 99 0.030
multi organism reproductive behavior GO:0044705 387 0.030
nucleobase containing compound metabolic process GO:0006139 406 0.030
cell type specific apoptotic process GO:0097285 4 0.030
single organism signaling GO:0044700 401 0.030
organonitrogen compound metabolic process GO:1901564 151 0.029
small molecule metabolic process GO:0044281 186 0.029
g protein coupled receptor signaling pathway GO:0007186 46 0.029
body morphogenesis GO:0010171 620 0.029
secretion by cell GO:0032940 138 0.029
female gamete generation GO:0007292 254 0.029
regulation of neurotransmitter levels GO:0001505 36 0.029
single organism reproductive process GO:0044702 1196 0.029
single organism organelle organization GO:1902589 501 0.028
regulation of developmental process GO:0050793 684 0.028
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.028
phosphorus metabolic process GO:0006793 232 0.028
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.028
nucleoside triphosphate metabolic process GO:0009141 87 0.027
gamete generation GO:0007276 461 0.027
catabolic process GO:0009056 318 0.027
positive regulation of developmental process GO:0051094 408 0.027
response to abiotic stimulus GO:0009628 152 0.027
regulation of metabolic process GO:0019222 478 0.027
Human
myosin filament assembly GO:0031034 138 0.026
positive regulation of cellular process GO:0048522 332 0.026
Mouse
negative regulation of metabolic process GO:0009892 240 0.026
aromatic compound biosynthetic process GO:0019438 192 0.026
response to chemical GO:0042221 356 0.026
negative regulation of cellular process GO:0048523 239 0.026
single organism transport GO:0044765 447 0.025
regulation of response to stimulus GO:0048583 243 0.025
Human
myosin filament organization GO:0031033 138 0.025
response to wounding GO:0009611 4 0.025
Human
growth GO:0040007 562 0.025
vulval development GO:0040025 333 0.025
cellular protein modification process GO:0006464 207 0.025
aromatic compound catabolic process GO:0019439 116 0.025
ribonucleoside metabolic process GO:0009119 98 0.024
macromolecular complex assembly GO:0065003 193 0.024
regulation of cell communication GO:0010646 176 0.024
cyclic nucleotide biosynthetic process GO:0009190 2 0.023
regulation of gene expression GO:0010468 366 0.022
Human
actin filament based process GO:0030029 191 0.022
glycosyl compound metabolic process GO:1901657 100 0.022
organelle fission GO:0048285 363 0.022
sex differentiation GO:0007548 909 0.022
organic cyclic compound catabolic process GO:1901361 119 0.022
regulation of signaling GO:0023051 172 0.022
head development GO:0060322 1 0.021
muscle cell development GO:0055001 158 0.021
regulation of synaptic plasticity GO:0048167 1 0.021
germ cell development GO:0007281 351 0.021
regulation of post embryonic development GO:0048580 260 0.021
purine nucleotide metabolic process GO:0006163 95 0.021
cell cycle GO:0007049 526 0.021
oviposition GO:0018991 364 0.020
purine ribonucleoside metabolic process GO:0046128 92 0.020
membrane organization GO:0061024 135 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.020
striated muscle cell differentiation GO:0051146 158 0.020
receptor mediated endocytosis GO:0006898 715 0.020
cell cycle process GO:0022402 482 0.020
multi organism behavior GO:0051705 389 0.020
positive regulation of gtp catabolic process GO:0033126 28 0.019
cellular catabolic process GO:0044248 199 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
regulation of neurotransmitter secretion GO:0046928 16 0.019
cellular biosynthetic process GO:0044249 315 0.019
negative regulation of macromolecule metabolic process GO:0010605 229 0.019
molting cycle GO:0042303 281 0.019
protein modification process GO:0036211 207 0.019
heterocycle catabolic process GO:0046700 119 0.019
regulation of g protein coupled receptor protein signaling pathway GO:0008277 4 0.018
carbohydrate derivative metabolic process GO:1901135 141 0.018
reproductive system development GO:0061458 850 0.018
response to external stimulus GO:0009605 289 0.018
Human
ribose phosphate metabolic process GO:0019693 99 0.018
gtp metabolic process GO:0046039 46 0.018
gene silencing GO:0016458 143 0.018
organic substance catabolic process GO:1901575 294 0.018
negative regulation of gene expression GO:0010629 217 0.018
single organism catabolic process GO:0044712 129 0.018
phagocytosis engulfment GO:0006911 98 0.018
cell surface receptor signaling pathway GO:0007166 149 0.018
muscle cell differentiation GO:0042692 171 0.018
carbohydrate derivative catabolic process GO:1901136 82 0.017
neuromuscular junction development GO:0007528 2 0.017
heterocycle biosynthetic process GO:0018130 187 0.017
memory GO:0007613 3 0.017
purine nucleoside catabolic process GO:0006152 75 0.017
gene expression GO:0010467 412 0.017
Human
establishment of organelle localization GO:0051656 123 0.017
nervous system development GO:0007399 253 0.017
nucleoside catabolic process GO:0009164 78 0.017
cellular response to abiotic stimulus GO:0071214 4 0.017
feeding behavior GO:0007631 70 0.017
cellular component morphogenesis GO:0032989 318 0.017
striated muscle cell development GO:0055002 157 0.017
nucleoside phosphate catabolic process GO:1901292 77 0.017
calcium mediated signaling GO:0019722 3 0.017
transcription from rna polymerase ii promoter GO:0006366 149 0.017
establishment of localization in cell GO:0051649 318 0.017
regulation of nitrogen compound metabolic process GO:0051171 222 0.017
nucleoside triphosphate catabolic process GO:0009143 72 0.017
cellular localization GO:0051641 360 0.017
posttranscriptional gene silencing GO:0016441 143 0.017
single fertilization GO:0007338 61 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.016
hermaphrodite genitalia development GO:0040035 734 0.016
ribonucleotide catabolic process GO:0009261 75 0.016
chemotaxis GO:0006935 120 0.016
striated muscle myosin thick filament assembly GO:0071688 138 0.016
negative regulation of developmental process GO:0051093 227 0.016
purine nucleoside metabolic process GO:0042278 92 0.016
nucleobase containing compound biosynthetic process GO:0034654 184 0.016
nucleic acid metabolic process GO:0090304 299 0.016
negative regulation of multicellular organismal process GO:0051241 236 0.016
nucleobase containing compound catabolic process GO:0034655 114 0.016
regulation of cellular biosynthetic process GO:0031326 189 0.016
macromolecule modification GO:0043412 218 0.016
organic cyclic compound biosynthetic process GO:1901362 195 0.016
nucleoside metabolic process GO:0009116 99 0.016
muscle structure development GO:0061061 191 0.016
cellular component biogenesis GO:0044085 297 0.016
regulation of filopodium assembly GO:0051489 2 0.015
protein complex biogenesis GO:0070271 186 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
cellular amine metabolic process GO:0044106 15 0.015
copulation GO:0007620 2 0.015
gene silencing by rna GO:0031047 143 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
purine containing compound catabolic process GO:0072523 75 0.015
cellular nitrogen compound biosynthetic process GO:0044271 192 0.015
nucleic acid templated transcription GO:0097659 169 0.015
nucleotide metabolic process GO:0009117 108 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.015
single organism behavior GO:0044708 83 0.014
rna interference GO:0016246 137 0.014
cellular macromolecule biosynthetic process GO:0034645 247 0.014
organelle localization GO:0051640 127 0.014
regulation of rna metabolic process GO:0051252 173 0.014
neurotransmitter secretion GO:0007269 26 0.014
development of primary sexual characteristics GO:0045137 840 0.014
ribonucleoside triphosphate metabolic process GO:0009199 87 0.014
purine ribonucleoside catabolic process GO:0046130 75 0.014
cellular macromolecular complex assembly GO:0034622 184 0.014
cell division GO:0051301 262 0.014
organonitrogen compound catabolic process GO:1901565 90 0.014
apoptotic cell clearance GO:0043277 111 0.014
regulation of nucleotide catabolic process GO:0030811 35 0.014
organic substance biosynthetic process GO:1901576 323 0.014
biosynthetic process GO:0009058 323 0.014
guanosine containing compound metabolic process GO:1901068 49 0.014
oocyte axis specification GO:0007309 2 0.014
positive regulation of synaptic transmission GO:0050806 24 0.014
macromolecule biosynthetic process GO:0009059 250 0.014
regulation of response to wounding GO:1903034 1 0.014
Human
macromolecular complex subunit organization GO:0043933 320 0.014
rho protein signal transduction GO:0007266 2 0.014
response to organic substance GO:0010033 131 0.014
ribonucleoside catabolic process GO:0042454 77 0.013
adult behavior GO:0030534 3 0.013
purine nucleoside triphosphate metabolic process GO:0009144 87 0.013
amine metabolic process GO:0009308 15 0.013
purine ribonucleotide metabolic process GO:0009150 95 0.013
purine nucleotide catabolic process GO:0006195 75 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
fertilization GO:0009566 63 0.013
cellular component movement GO:0006928 388 0.013
cyclic purine nucleotide metabolic process GO:0052652 2 0.013
protein metabolic process GO:0019538 422 0.013
response to heat GO:0009408 50 0.013
regulation of locomotion GO:0040012 161 0.013
regulation of nematode larval development GO:0061062 260 0.013
regulation of primary metabolic process GO:0080090 292 0.013
lipid metabolic process GO:0006629 77 0.013
meiotic cell cycle GO:0051321 335 0.013
cation transport GO:0006812 78 0.013
cellular protein complex assembly GO:0043623 178 0.013
synaptic transmission GO:0007268 106 0.013
positive regulation of nucleoside metabolic process GO:0045979 28 0.013
regulation of multicellular organismal development GO:2000026 317 0.013
filopodium assembly GO:0046847 2 0.013
establishment of protein localization to membrane GO:0090150 3 0.013
phagocytosis GO:0006909 115 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
regulation of neuromuscular synaptic transmission GO:1900073 1 0.012
membrane invagination GO:0010324 98 0.012
purine nucleoside triphosphate catabolic process GO:0009146 72 0.012
transmembrane transport GO:0055085 110 0.012
neurotransmitter metabolic process GO:0042133 6 0.012
regulation of localization GO:0032879 194 0.012
Mouse
regulation of apoptotic signaling pathway GO:2001233 1 0.012
positive regulation of neurotransmitter transport GO:0051590 11 0.012
negative regulation of post embryonic development GO:0048581 208 0.012
vesicle organization GO:0016050 15 0.012
nucleotide catabolic process GO:0009166 77 0.012
macromolecule catabolic process GO:0009057 202 0.012
protein complex assembly GO:0006461 186 0.012
guanosine containing compound catabolic process GO:1901069 48 0.012
engulfment of apoptotic cell GO:0043652 94 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.012
regulation of exocytosis GO:0017157 1 0.012
Mouse
rna metabolic process GO:0016070 228 0.012
purine ribonucleotide catabolic process GO:0009154 75 0.012
cellular protein metabolic process GO:0044267 279 0.011
skeletal muscle organ development GO:0060538 3 0.011
positive regulation of rna biosynthetic process GO:1902680 102 0.011
gtp catabolic process GO:0006184 46 0.011
response to acid chemical GO:0001101 4 0.011
defense response GO:0006952 296 0.011
ras protein signal transduction GO:0007265 31 0.011
regulation of reproductive process GO:2000241 66 0.011
response to inorganic substance GO:0010035 50 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
rna localization GO:0006403 3 0.011
regulation of purine nucleotide metabolic process GO:1900542 37 0.011
male sex differentiation GO:0046661 86 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
purine containing compound metabolic process GO:0072521 95 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
regulation of intracellular signal transduction GO:1902531 77 0.011
regulation of oviposition GO:0046662 43 0.011
detection of external stimulus GO:0009581 4 0.011
system process GO:0003008 136 0.010
regulation of gtp catabolic process GO:0033124 32 0.010
genitalia development GO:0048806 741 0.010
regulation of nucleotide metabolic process GO:0006140 37 0.010
meiotic nuclear division GO:0007126 300 0.010
hyperosmotic response GO:0006972 19 0.010
acetate ester metabolic process GO:1900619 4 0.010
neurotransmitter transport GO:0006836 32 0.010
negative regulation of cellular metabolic process GO:0031324 95 0.010
regulation of nuclear division GO:0051783 115 0.010
rna biosynthetic process GO:0032774 169 0.010

tom-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.016
immune system disease DOID:2914 0 0.011