Caenorhabditis elegans

89 known processes

unc-15 (CELE_F07A5.7)

Protein UNC-15

unc-15 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sarcomere organization GO:0045214 10 1.000
muscle tissue development GO:0060537 1 0.833
skeletal muscle thin filament assembly GO:0030240 3 0.787
cellular component morphogenesis GO:0032989 318 0.776
striated muscle cell development GO:0055002 157 0.718
organelle assembly GO:0070925 214 0.705
body morphogenesis GO:0010171 620 0.704
cytoskeleton organization GO:0007010 339 0.679
embryonic body morphogenesis GO:0010172 49 0.672
cellular component assembly GO:0022607 293 0.615
embryo development GO:0009790 3052 0.610
skeletal muscle organ development GO:0060538 3 0.590
actin filament based process GO:0030029 191 0.580
cellular component assembly involved in morphogenesis GO:0010927 183 0.574
locomotion GO:0040011 1634 0.554
muscle cell development GO:0055001 158 0.537
post embryonic development GO:0009791 2152 0.519
actomyosin structure organization GO:0031032 154 0.468
anatomical structure formation involved in morphogenesis GO:0048646 250 0.467
organelle organization GO:0006996 783 0.442
establishment of localization GO:0051234 1171 0.420
female gamete generation GO:0007292 254 0.416
skeletal myofibril assembly GO:0014866 7 0.414
actin cytoskeleton organization GO:0030036 184 0.413
single organism organelle organization GO:1902589 501 0.409
cellular component biogenesis GO:0044085 297 0.400
gamete generation GO:0007276 461 0.389
embryo development ending in birth or egg hatching GO:0009792 2992 0.388
myofibril assembly GO:0030239 154 0.352
muscle organ development GO:0007517 26 0.345
regulation of atp catabolic process GO:1903289 3 0.328
embryonic morphogenesis GO:0048598 152 0.324
nucleobase containing compound metabolic process GO:0006139 406 0.319
muscle cell differentiation GO:0042692 171 0.311
transport GO:0006810 1093 0.299
sexual reproduction GO:0019953 546 0.294
cellular protein complex assembly GO:0043623 178 0.274
protein complex subunit organization GO:0071822 280 0.274
inductive cell migration GO:0040039 145 0.272
cellular macromolecular complex assembly GO:0034622 184 0.271
muscle structure development GO:0061061 191 0.269
single organism localization GO:1902578 518 0.253
muscle contraction GO:0006936 43 0.253
nucleoside triphosphate catabolic process GO:0009143 72 0.235
myosin filament assembly GO:0031034 138 0.225
protein complex biogenesis GO:0070271 186 0.219
ribonucleotide catabolic process GO:0009261 75 0.217
endocytosis GO:0006897 819 0.203
oviposition GO:0018991 364 0.201
multicellular organism reproduction GO:0032504 819 0.200
nucleoside catabolic process GO:0009164 78 0.198
germ cell development GO:0007281 351 0.198
cell development GO:0048468 696 0.193
vesicle mediated transport GO:0016192 852 0.190
receptor mediated endocytosis GO:0006898 715 0.190
regulation of cytoskeleton organization GO:0051493 41 0.187
single organism reproductive process GO:0044702 1196 0.184
ovulation GO:0030728 33 0.182
tissue development GO:0009888 112 0.178
Fly
striated muscle cell differentiation GO:0051146 158 0.173
cellular component movement GO:0006928 388 0.169
negative regulation of biological process GO:0048519 567 0.167
nucleic acid metabolic process GO:0090304 299 0.165
macromolecular complex subunit organization GO:0043933 320 0.161
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.158
regulation of multicellular organismal process GO:0051239 726 0.157
meiotic nuclear division GO:0007126 300 0.152
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.149
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.148
signaling GO:0023052 401 0.144
regulation of metabolic process GO:0019222 478 0.143
ribonucleotide metabolic process GO:0009259 99 0.139
cell cycle process GO:0022402 482 0.138
muscle system process GO:0003012 43 0.137
protein complex assembly GO:0006461 186 0.135
striated muscle myosin thick filament assembly GO:0071688 138 0.133
multicellular organismal aging GO:0010259 812 0.133
regulation of primary metabolic process GO:0080090 292 0.132
regulation of growth GO:0040008 409 0.131
cell motility GO:0048870 313 0.125
cellular homeostasis GO:0019725 22 0.121
actin filament organization GO:0007015 21 0.121
ribonucleoside triphosphate catabolic process GO:0009203 72 0.120
multi organism reproductive process GO:0044703 867 0.117
regulation of nitrogen compound metabolic process GO:0051171 222 0.115
cellular nitrogen compound biosynthetic process GO:0044271 192 0.113
molting cycle GO:0042303 281 0.112
regulation of actin filament based process GO:0032970 22 0.110
meiotic cell cycle GO:0051321 335 0.110
purine ribonucleoside catabolic process GO:0046130 75 0.108
tube morphogenesis GO:0035239 79 0.107
mitotic cell cycle process GO:1903047 194 0.104
regulation of developmental growth GO:0048638 389 0.104
nucleotide catabolic process GO:0009166 77 0.104
growth GO:0040007 562 0.103
protein metabolic process GO:0019538 422 0.102
nucleoside phosphate catabolic process GO:1901292 77 0.101
organophosphate catabolic process GO:0046434 81 0.100
neuron development GO:0048666 199 0.099
determination of adult lifespan GO:0008340 812 0.098
single organism transport GO:0044765 447 0.096
positive regulation of multicellular organism growth GO:0040018 352 0.093
regulation of cellular metabolic process GO:0031323 305 0.093
signal transduction GO:0007165 317 0.092
cell projection organization GO:0030030 231 0.091
spicule insertion GO:0034609 2 0.091
biosynthetic process GO:0009058 323 0.091
negative regulation of metabolic process GO:0009892 240 0.090
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.089
regulation of rna biosynthetic process GO:2001141 165 0.089
positive regulation of multicellular organismal process GO:0051240 417 0.088
oogenesis GO:0048477 229 0.088
cytokinesis GO:0000910 80 0.087
nucleoside phosphate metabolic process GO:0006753 108 0.083
regulation of catalytic activity GO:0050790 78 0.083
regulation of nucleoside metabolic process GO:0009118 37 0.081
cellular biosynthetic process GO:0044249 315 0.081
macromolecule biosynthetic process GO:0009059 250 0.081
organic cyclic compound catabolic process GO:1901361 119 0.080
regulation of biological quality GO:0065008 741 0.079
behavior GO:0007610 527 0.079
aromatic compound catabolic process GO:0019439 116 0.078
single organism signaling GO:0044700 401 0.077
multi multicellular organism process GO:0044706 390 0.076
aging GO:0007568 812 0.075
macromolecule catabolic process GO:0009057 202 0.075
multi organism behavior GO:0051705 389 0.075
purine containing compound catabolic process GO:0072523 75 0.074
reproductive structure development GO:0048608 850 0.074
purine nucleoside triphosphate catabolic process GO:0009146 72 0.073
purine nucleotide metabolic process GO:0006163 95 0.073
developmental growth GO:0048589 412 0.073
purine nucleoside catabolic process GO:0006152 75 0.072
posttranscriptional regulation of gene expression GO:0010608 166 0.072
ribose phosphate metabolic process GO:0019693 99 0.072
mesoderm development GO:0007498 27 0.071
Fly
organic substance catabolic process GO:1901575 294 0.071
striated muscle contraction GO:0006941 17 0.071
macromolecule localization GO:0033036 771 0.071
homeostatic process GO:0042592 51 0.071
ribonucleoside catabolic process GO:0042454 77 0.070
regulation of gene expression GO:0010468 366 0.070
multicellular organism growth GO:0035264 385 0.069
bmp signaling pathway GO:0030509 3 0.069
myosin filament organization GO:0031033 138 0.068
organ development GO:0048513 1102 0.067
apical junction assembly GO:0043297 1 0.067
regulation of cellular biosynthetic process GO:0031326 189 0.066
positive regulation of growth GO:0045927 369 0.066
purine nucleotide catabolic process GO:0006195 75 0.066
regulation of developmental process GO:0050793 684 0.065
muscle organ morphogenesis GO:0048644 4 0.065
carbohydrate derivative catabolic process GO:1901136 82 0.064
negative regulation of macromolecule metabolic process GO:0010605 229 0.064
reproductive behavior GO:0019098 387 0.063
heterocycle catabolic process GO:0046700 119 0.063
macromolecular complex assembly GO:0065003 193 0.062
carbohydrate derivative metabolic process GO:1901135 141 0.062
positive regulation of developmental growth GO:0048639 354 0.059
regulation of macromolecule metabolic process GO:0060255 421 0.059
multicellular organismal reproductive process GO:0048609 815 0.059
multicellular organismal reproductive behavior GO:0033057 384 0.058
maintenance of location GO:0051235 580 0.058
regulation of atpase activity GO:0043462 3 0.057
ribonucleoside triphosphate metabolic process GO:0009199 87 0.057
collagen and cuticulin based cuticle development GO:0040002 99 0.057
cytoskeleton dependent cytokinesis GO:0061640 35 0.056
gene silencing GO:0016458 143 0.056
catabolic process GO:0009056 318 0.055
atp metabolic process GO:0046034 42 0.055
genitalia development GO:0048806 741 0.055
regulation of biosynthetic process GO:0009889 189 0.053
nucleoside metabolic process GO:0009116 99 0.053
lipid storage GO:0019915 565 0.053
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.053
negative regulation of cellular process GO:0048523 239 0.052
regulation of cellular component size GO:0032535 40 0.052
rna metabolic process GO:0016070 228 0.052
pharyngeal pumping GO:0043050 58 0.051
regulation of system process GO:0044057 27 0.051
cellular nitrogen compound catabolic process GO:0044270 119 0.050
somatic muscle development GO:0007525 1 0.050
cellular catabolic process GO:0044248 199 0.049
gonad development GO:0008406 840 0.049
organonitrogen compound catabolic process GO:1901565 90 0.048
positive regulation of developmental process GO:0051094 408 0.048
system process GO:0003008 136 0.048
regulation of molecular function GO:0065009 89 0.047
neuron recognition GO:0008038 83 0.047
regulation of muscle system process GO:0090257 20 0.047
organic substance biosynthetic process GO:1901576 323 0.046
nucleoside triphosphate metabolic process GO:0009141 87 0.046
neuron projection development GO:0031175 187 0.046
nucleotide metabolic process GO:0009117 108 0.046
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.046
regulation of multicellular organism growth GO:0040014 373 0.045
purine ribonucleoside metabolic process GO:0046128 92 0.045
cell migration GO:0016477 306 0.045
purine nucleoside monophosphate catabolic process GO:0009128 28 0.045
multi organism reproductive behavior GO:0044705 387 0.045
muscle fiber development GO:0048747 2 0.044
nucleoside monophosphate metabolic process GO:0009123 46 0.043
atp catabolic process GO:0006200 27 0.043
establishment or maintenance of cell polarity GO:0007163 63 0.043
regulation of purine nucleotide catabolic process GO:0033121 35 0.042
sex differentiation GO:0007548 909 0.041
small gtpase mediated signal transduction GO:0007264 32 0.041
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.041
lipid localization GO:0010876 573 0.041
regulation of cellular catabolic process GO:0031329 51 0.041
phagocytosis GO:0006909 115 0.040
establishment of localization in cell GO:0051649 318 0.039
regulation of purine nucleotide metabolic process GO:1900542 37 0.039
regulation of cell communication GO:0010646 176 0.039
negative regulation of gene expression epigenetic GO:0045814 2 0.038
cell death GO:0008219 547 0.038
purine nucleoside metabolic process GO:0042278 92 0.037
reproductive system development GO:0061458 850 0.037
localization of cell GO:0051674 313 0.037
cuticle development GO:0042335 100 0.036
gene expression GO:0010467 412 0.035
purine nucleoside monophosphate metabolic process GO:0009126 43 0.035
neurogenesis GO:0022008 236 0.035
regulation of nucleic acid templated transcription GO:1903506 165 0.035
regulation of locomotion GO:0040012 161 0.035
tube development GO:0035295 126 0.034
purine nucleoside triphosphate metabolic process GO:0009144 87 0.034
purine containing compound metabolic process GO:0072521 95 0.034
establishment of cell polarity GO:0030010 46 0.034
multicellular organismal movement GO:0050879 2 0.033
intracellular signal transduction GO:0035556 96 0.033
protein catabolic process GO:0030163 162 0.033
regulation of ras protein signal transduction GO:0046578 41 0.033
meiotic cell cycle process GO:1903046 170 0.033
response to chemical GO:0042221 356 0.032
rna biosynthetic process GO:0032774 169 0.032
organophosphate metabolic process GO:0019637 125 0.032
transcription dna templated GO:0006351 168 0.032
cell part morphogenesis GO:0032990 152 0.032
nucleobase containing compound catabolic process GO:0034655 114 0.032
regulation of multicellular organismal development GO:2000026 317 0.031
epithelial tube morphogenesis GO:0060562 1 0.031
generation of neurons GO:0048699 235 0.031
purine ribonucleotide catabolic process GO:0009154 75 0.031
directional locomotion GO:0033058 14 0.031
eating behavior GO:0042755 59 0.030
positive regulation of ras gtpase activity GO:0032320 19 0.030
regulation of gtpase activity GO:0043087 30 0.030
developmental process involved in reproduction GO:0003006 1165 0.029
nucleobase containing compound biosynthetic process GO:0034654 184 0.029
regulation of transcription dna templated GO:0006355 164 0.029
glycosyl compound metabolic process GO:1901657 100 0.028
glycosyl compound catabolic process GO:1901658 79 0.028
regulation of hydrolase activity GO:0051336 45 0.028
actin filament based movement GO:0030048 4 0.028
purine ribonucleotide metabolic process GO:0009150 95 0.028
protein phosphorylation GO:0006468 85 0.028
microtubule based process GO:0007017 182 0.027
heterocycle biosynthetic process GO:0018130 187 0.027
regulation of nucleotide catabolic process GO:0030811 35 0.027
ras protein signal transduction GO:0007265 31 0.027
nucleobase containing small molecule metabolic process GO:0055086 115 0.027
anatomical structure homeostasis GO:0060249 11 0.026
dna metabolic process GO:0006259 74 0.026
positive regulation of calcium ion transport GO:0051928 1 0.026
secretion GO:0046903 147 0.026
regulation of nucleotide metabolic process GO:0006140 37 0.026
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.026
cellular ion homeostasis GO:0006873 11 0.025
phosphorus metabolic process GO:0006793 232 0.025
cellular macromolecule biosynthetic process GO:0034645 247 0.025
response to biotic stimulus GO:0009607 101 0.025
programmed cell death GO:0012501 500 0.025
negative regulation of cellular metabolic process GO:0031324 95 0.025
negative regulation of cellular biosynthetic process GO:0031327 65 0.025
regulation of organelle organization GO:0033043 164 0.025
regulation of phosphate metabolic process GO:0019220 81 0.024
organonitrogen compound metabolic process GO:1901564 151 0.024
synaptic transmission GO:0007268 106 0.024
cellular localization GO:0051641 360 0.024
nervous system development GO:0007399 253 0.024
regulation of phosphorus metabolic process GO:0051174 81 0.023
ribonucleoside monophosphate metabolic process GO:0009161 45 0.023
regulation of rna metabolic process GO:0051252 173 0.023
macromolecule modification GO:0043412 218 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.023
protein modification process GO:0036211 207 0.023
neuron differentiation GO:0030182 217 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.023
protein localization GO:0008104 205 0.023
organelle fission GO:0048285 363 0.023
actin filament bundle assembly GO:0051017 3 0.022
negative regulation of multicellular organismal process GO:0051241 236 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.022
ribonucleoside metabolic process GO:0009119 98 0.021
cellular response to organic substance GO:0071310 119 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.021
death GO:0016265 547 0.021
aromatic compound biosynthetic process GO:0019438 192 0.021
positive regulation of gtp catabolic process GO:0033126 28 0.021
response to wounding GO:0009611 4 0.021
regulation of gene expression epigenetic GO:0040029 163 0.020
calcium ion homeostasis GO:0055074 6 0.020
positive regulation of cellular metabolic process GO:0031325 178 0.020
regulation of transport GO:0051049 91 0.020
gtp metabolic process GO:0046039 46 0.020
mitotic nuclear division GO:0007067 89 0.020
ribonucleoprotein complex assembly GO:0022618 4 0.020
regulation of cell morphogenesis GO:0022604 40 0.019
organic cyclic compound biosynthetic process GO:1901362 195 0.019
hermaphrodite genitalia development GO:0040035 734 0.019
membrane invagination GO:0010324 98 0.019
cellular response to chemical stimulus GO:0070887 129 0.019
gtp catabolic process GO:0006184 46 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.019
regulation of cell development GO:0060284 49 0.019
cell projection morphogenesis GO:0048858 148 0.018
transcription from rna polymerase ii promoter GO:0006366 149 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.018
regulation of signaling GO:0023051 172 0.018
digestive system development GO:0055123 122 0.018
rho protein signal transduction GO:0007266 2 0.018
feeding behavior GO:0007631 70 0.018
chromosome segregation GO:0007059 180 0.018
backward locomotion GO:0043057 11 0.018
regulation of response to stimulus GO:0048583 243 0.018
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.018
regulation of small gtpase mediated signal transduction GO:0051056 41 0.018
divalent metal ion transport GO:0070838 17 0.018
male anatomical structure morphogenesis GO:0090598 78 0.017
positive regulation of hydrolase activity GO:0051345 38 0.017
monovalent inorganic cation transport GO:0015672 33 0.017
single organism catabolic process GO:0044712 129 0.017
single organism behavior GO:0044708 83 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.017
adult locomotory behavior GO:0008344 1 0.017
regulation of macromolecule biosynthetic process GO:0010556 189 0.017
apoptotic process GO:0006915 478 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
metal ion transport GO:0030001 49 0.016
negative regulation of gene expression GO:0010629 217 0.016
regulation of localization GO:0032879 194 0.016
regulation of anatomical structure size GO:0090066 46 0.016
regulation of actin cytoskeleton organization GO:0032956 17 0.016
nucleic acid templated transcription GO:0097659 169 0.016
pattern specification process GO:0007389 59 0.016
negative regulation of rna biosynthetic process GO:1902679 53 0.016
positive regulation of metabolic process GO:0009893 187 0.015
cellular protein complex disassembly GO:0043624 18 0.015
cell cell junction assembly GO:0007043 2 0.015
cell division GO:0051301 262 0.015
adult behavior GO:0030534 3 0.015
cellular protein modification process GO:0006464 207 0.015
regulation of signal transduction GO:0009966 135 0.015
cell recognition GO:0008037 85 0.015
negative regulation of developmental process GO:0051093 227 0.015
ribonucleoside monophosphate catabolic process GO:0009158 28 0.015
small molecule metabolic process GO:0044281 186 0.014
regulation of ion transport GO:0043269 39 0.014
chemosensory behavior GO:0007635 33 0.014
negative regulation of nematode larval development GO:0061064 208 0.014
negative regulation of biosynthetic process GO:0009890 65 0.014
regulation of atp metabolic process GO:1903578 5 0.014
regulation of catabolic process GO:0009894 57 0.014
regulation of secretion GO:0051046 29 0.014
cell junction organization GO:0034330 18 0.013
cation homeostasis GO:0055080 20 0.013
engulfment of apoptotic cell GO:0043652 94 0.013
regulation of protein stability GO:0031647 3 0.013
regulation of actin filament polymerization GO:0030833 11 0.013
regulation of intracellular signal transduction GO:1902531 77 0.013
response to oxygen containing compound GO:1901700 44 0.013
organic substance transport GO:0071702 113 0.013
regulation of muscle cell differentiation GO:0051147 1 0.013
gene silencing by rna GO:0031047 143 0.013
apoptotic cell clearance GO:0043277 111 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.012
phagocytosis engulfment GO:0006911 98 0.012
membrane organization GO:0061024 135 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
ion transport GO:0006811 113 0.012
cell morphogenesis involved in differentiation GO:0000904 112 0.012
cellular metal ion homeostasis GO:0006875 7 0.012
locomotory behavior GO:0007626 40 0.012
regulation of calcium ion transport GO:0051924 3 0.012
positive regulation of nucleoside metabolic process GO:0045979 28 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
secretion by cell GO:0032940 138 0.011
posttranscriptional gene silencing GO:0016441 143 0.011
cellular protein metabolic process GO:0044267 279 0.011
negative regulation of transcription dna templated GO:0045892 53 0.011
response to acid chemical GO:0001101 4 0.011
regulation of nematode larval development GO:0061062 260 0.011
sensory perception of bitter taste GO:0050913 3 0.011
axonal fasciculation GO:0007413 79 0.011
regulation of muscle contraction GO:0006937 20 0.011
axon development GO:0061564 163 0.011
regulation of anatomical structure morphogenesis GO:0022603 51 0.010
single organism intracellular transport GO:1902582 70 0.010
ribosome biogenesis GO:0042254 4 0.010
rna interference GO:0016246 137 0.010
single organism membrane organization GO:0044802 35 0.010
nucleoside monophosphate catabolic process GO:0009125 28 0.010
muscle thin filament assembly GO:0071689 5 0.010
cell cycle GO:0007049 526 0.010

unc-15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.186
muscular disease DOID:0080000 0 0.186
heart disease DOID:114 0 0.186
cardiomyopathy DOID:0050700 0 0.186
disease of anatomical entity DOID:7 0 0.186
cardiovascular system disease DOID:1287 0 0.186
musculoskeletal system disease DOID:17 0 0.186
muscle tissue disease DOID:66 0 0.186
dilated cardiomyopathy DOID:12930 0 0.051
intrinsic cardiomyopathy DOID:0060036 0 0.051
hypertrophic cardiomyopathy DOID:11984 0 0.026
progeria DOID:3911 0 0.017
lipodystrophy DOID:811 0 0.012
skin disease DOID:37 0 0.012
integumentary system disease DOID:16 0 0.012
familial partial lipodystrophy DOID:0050440 0 0.012
disease of metabolism DOID:0014667 0 0.012
congenital muscular dystrophy DOID:0050557 0 0.011
muscular dystrophy DOID:9884 0 0.011
inherited metabolic disorder DOID:655 0 0.011