Caenorhabditis elegans

83 known processes

vrk-1 (CELE_F28B12.3)

Protein VRK-1

vrk-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
reproductive system development GO:0061458 850 0.764
development of primary sexual characteristics GO:0045137 840 0.611
embryo development ending in birth or egg hatching GO:0009792 2992 0.602
sex differentiation GO:0007548 909 0.570
genitalia development GO:0048806 741 0.557
organ development GO:0048513 1102 0.554
gonad development GO:0008406 840 0.516
organelle organization GO:0006996 783 0.490
Human Fly
positive regulation of cellular process GO:0048522 332 0.472
Fly
cell cycle process GO:0022402 482 0.451
Fly
chromosome organization GO:0051276 104 0.398
Human Fly
transport GO:0006810 1093 0.366
developmental process involved in reproduction GO:0003006 1165 0.352
cell cycle GO:0007049 526 0.334
Fly
cell projection organization GO:0030030 231 0.332
organic substance biosynthetic process GO:1901576 323 0.309
single organism organelle organization GO:1902589 501 0.296
Human Fly
apoptotic process GO:0006915 478 0.280
macromolecular complex subunit organization GO:0043933 320 0.278
Human Fly
reproductive structure development GO:0048608 850 0.276
post embryonic development GO:0009791 2152 0.260
regulation of macromolecule metabolic process GO:0060255 421 0.252
programmed cell death GO:0012501 500 0.238
macromolecule biosynthetic process GO:0009059 250 0.230
transcription from rna polymerase ii promoter GO:0006366 149 0.229
regulation of cellular metabolic process GO:0031323 305 0.229
Human Fly
hermaphrodite genitalia development GO:0040035 734 0.225
protein metabolic process GO:0019538 422 0.222
gene expression GO:0010467 412 0.210
organelle fission GO:0048285 363 0.207
Fly
regulation of multicellular organismal process GO:0051239 726 0.207
embryo development GO:0009790 3052 0.203
protein modification process GO:0036211 207 0.193
regulation of vulval development GO:0040028 248 0.188
cellular macromolecule biosynthetic process GO:0034645 247 0.184
death GO:0016265 547 0.180
cellular protein metabolic process GO:0044267 279 0.163
body morphogenesis GO:0010171 620 0.163
meiotic nuclear division GO:0007126 300 0.162
Fly
chromosome segregation GO:0007059 180 0.162
Fly
vesicle mediated transport GO:0016192 852 0.157
post embryonic organ development GO:0048569 336 0.155
regulation of post embryonic development GO:0048580 260 0.151
signal transduction GO:0007165 317 0.149
axon development GO:0061564 163 0.149
single organism reproductive process GO:0044702 1196 0.149
multicellular organism reproduction GO:0032504 819 0.145
negative regulation of biological process GO:0048519 567 0.141
locomotion GO:0040011 1634 0.137
multicellular organismal reproductive process GO:0048609 815 0.134
signaling GO:0023052 401 0.130
vulval development GO:0040025 333 0.129
mitotic cell cycle process GO:1903047 194 0.129
Fly
cell death GO:0008219 547 0.125
cellular component assembly GO:0022607 293 0.122
Fly
positive regulation of cellular metabolic process GO:0031325 178 0.120
Fly
neuron projection development GO:0031175 187 0.117
regulation of organelle organization GO:0033043 164 0.113
cellular component biogenesis GO:0044085 297 0.113
Fly
regulation of response to stimulus GO:0048583 243 0.108
nucleic acid metabolic process GO:0090304 299 0.108
cell division GO:0051301 262 0.107
sexual reproduction GO:0019953 546 0.106
neuron differentiation GO:0030182 217 0.102
negative regulation of multicellular organismal process GO:0051241 236 0.099
regulation of cellular component organization GO:0051128 248 0.099
negative regulation of developmental process GO:0051093 227 0.099
regulation of rna biosynthetic process GO:2001141 165 0.095
behavior GO:0007610 527 0.093
positive regulation of metabolic process GO:0009893 187 0.092
Fly
meiotic cell cycle GO:0051321 335 0.092
Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.091
regulation of biological quality GO:0065008 741 0.090
cellular component movement GO:0006928 388 0.090
single organism signaling GO:0044700 401 0.089
oviposition GO:0018991 364 0.085
multi multicellular organism process GO:0044706 390 0.085
regulation of nitrogen compound metabolic process GO:0051171 222 0.085
multi organism reproductive process GO:0044703 867 0.084
macromolecule localization GO:0033036 771 0.082
cellular macromolecular complex assembly GO:0034622 184 0.077
neurogenesis GO:0022008 236 0.076
Fly
regulation of cell cycle process GO:0010564 145 0.074
regulation of transcription dna templated GO:0006355 164 0.072
establishment of localization GO:0051234 1171 0.072
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.070
purine ribonucleoside catabolic process GO:0046130 75 0.070
negative regulation of metabolic process GO:0009892 240 0.070
tissue development GO:0009888 112 0.069
negative regulation of gene expression GO:0010629 217 0.067
rna biosynthetic process GO:0032774 169 0.066
protein complex subunit organization GO:0071822 280 0.065
Fly
aging GO:0007568 812 0.064
aromatic compound biosynthetic process GO:0019438 192 0.064
negative regulation of gene expression epigenetic GO:0045814 2 0.064
multicellular organismal aging GO:0010259 812 0.064
localization of cell GO:0051674 313 0.064
multi organism behavior GO:0051705 389 0.063
regulation of rna metabolic process GO:0051252 173 0.063
ribonucleotide metabolic process GO:0009259 99 0.062
protein localization GO:0008104 205 0.062
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.061
cell migration GO:0016477 306 0.061
cellular nitrogen compound biosynthetic process GO:0044271 192 0.061
cell surface receptor signaling pathway GO:0007166 149 0.061
epithelium development GO:0060429 68 0.061
macromolecule modification GO:0043412 218 0.059
regulation of primary metabolic process GO:0080090 292 0.059
regulation of multicellular organismal development GO:2000026 317 0.059
chromatin modification GO:0016568 32 0.059
Human Fly
negative regulation of nematode larval development GO:0061064 208 0.059
protein complex assembly GO:0006461 186 0.057
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.057
maintenance of location GO:0051235 580 0.056
biosynthetic process GO:0009058 323 0.056
regulation of cell cycle GO:0051726 194 0.055
cellular catabolic process GO:0044248 199 0.055
negative regulation of vulval development GO:0040027 206 0.054
cellular localization GO:0051641 360 0.054
single organism localization GO:1902578 518 0.054
cell projection morphogenesis GO:0048858 148 0.054
neuron development GO:0048666 199 0.053
regulation of macromolecule biosynthetic process GO:0010556 189 0.052
head development GO:0060322 1 0.051
nucleoside triphosphate catabolic process GO:0009143 72 0.051
microtubule based process GO:0007017 182 0.051
Fly
organonitrogen compound metabolic process GO:1901564 151 0.050
regulation of apoptotic process GO:0042981 36 0.049
lipid storage GO:0019915 565 0.049
cell development GO:0048468 696 0.049
Fly
cellular biosynthetic process GO:0044249 315 0.048
negative regulation of cellular process GO:0048523 239 0.047
reproductive behavior GO:0019098 387 0.047
positive regulation of catalytic activity GO:0043085 59 0.046
regulation of cell communication GO:0010646 176 0.045
catabolic process GO:0009056 318 0.045
meiotic cell cycle process GO:1903046 170 0.044
Fly
regulation of nematode larval development GO:0061062 260 0.043
regulation of cell differentiation GO:0045595 81 0.042
regulation of gene expression GO:0010468 366 0.042
lipid localization GO:0010876 573 0.041
nucleobase containing compound metabolic process GO:0006139 406 0.041
endocytosis GO:0006897 819 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.041
purine ribonucleotide catabolic process GO:0009154 75 0.040
establishment of organelle localization GO:0051656 123 0.040
regulation of developmental process GO:0050793 684 0.040
generation of neurons GO:0048699 235 0.039
regulation of mitotic cell cycle GO:0007346 76 0.039
cellular response to dna damage stimulus GO:0006974 41 0.039
Fly
organonitrogen compound catabolic process GO:1901565 90 0.038
multi organism reproductive behavior GO:0044705 387 0.038
positive regulation of multicellular organismal process GO:0051240 417 0.038
dna conformation change GO:0071103 11 0.037
dna metabolic process GO:0006259 74 0.036
cellular protein modification process GO:0006464 207 0.036
gamete generation GO:0007276 461 0.036
cell type specific apoptotic process GO:0097285 4 0.036
regulation of cell division GO:0051302 142 0.036
cell motility GO:0048870 313 0.035
organelle localization GO:0051640 127 0.035
cytoskeleton organization GO:0007010 339 0.035
Fly
carbohydrate derivative metabolic process GO:1901135 141 0.035
glycosyl compound catabolic process GO:1901658 79 0.035
receptor mediated endocytosis GO:0006898 715 0.034
neuron recognition GO:0008038 83 0.034
multicellular organismal reproductive behavior GO:0033057 384 0.034
nucleoside catabolic process GO:0009164 78 0.034
cell proliferation GO:0008283 116 0.033
chromatin assembly or disassembly GO:0006333 1 0.033
carboxylic acid metabolic process GO:0019752 34 0.033
positive regulation of macromolecule metabolic process GO:0010604 149 0.032
regulation of protein metabolic process GO:0051246 81 0.032
cell recognition GO:0008037 85 0.032
organic acid metabolic process GO:0006082 47 0.032
posttranscriptional regulation of gene expression GO:0010608 166 0.031
nucleotide metabolic process GO:0009117 108 0.030
positive regulation of developmental process GO:0051094 408 0.030
rna metabolic process GO:0016070 228 0.030
regulation of meiotic cell cycle GO:0051445 136 0.030
peptidyl amino acid modification GO:0018193 58 0.030
Human Fly
regulation of metabolic process GO:0019222 478 0.030
Human Fly
cell part morphogenesis GO:0032990 152 0.030
determination of adult lifespan GO:0008340 812 0.030
positive regulation of neurogenesis GO:0050769 4 0.029
meiotic chromosome segregation GO:0045132 139 0.028
phagocytosis engulfment GO:0006911 98 0.027
nucleoside metabolic process GO:0009116 99 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.027
response to chemical GO:0042221 356 0.027
nucleic acid templated transcription GO:0097659 169 0.027
macromolecular complex assembly GO:0065003 193 0.027
anatomical structure formation involved in morphogenesis GO:0048646 250 0.026
cellular response to abiotic stimulus GO:0071214 4 0.025
regulation of molecular function GO:0065009 89 0.025
positive regulation of molecular function GO:0044093 61 0.025
growth GO:0040007 562 0.025
positive regulation of hydrolase activity GO:0051345 38 0.025
ribose phosphate metabolic process GO:0019693 99 0.025
positive regulation of rna metabolic process GO:0051254 103 0.025
spindle organization GO:0007051 92 0.025
Fly
meiosis i GO:0007127 19 0.025
Fly
cell fate commitment GO:0045165 139 0.024
single organism catabolic process GO:0044712 129 0.024
purine ribonucleoside metabolic process GO:0046128 92 0.024
organ morphogenesis GO:0009887 67 0.024
gene silencing by rna GO:0031047 143 0.023
positive regulation of vulval development GO:0040026 52 0.023
negative regulation of response to stimulus GO:0048585 73 0.023
small molecule metabolic process GO:0044281 186 0.023
response to wounding GO:0009611 4 0.023
transcription dna templated GO:0006351 168 0.023
regulation of cellular biosynthetic process GO:0031326 189 0.022
intracellular signal transduction GO:0035556 96 0.022
Human Fly
ribonucleoside triphosphate metabolic process GO:0009199 87 0.022
embryonic morphogenesis GO:0048598 152 0.022
posttranscriptional gene silencing GO:0016441 143 0.022
organophosphate metabolic process GO:0019637 125 0.022
organic substance catabolic process GO:1901575 294 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.022
digestive tract development GO:0048565 122 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.022
positive regulation of biosynthetic process GO:0009891 109 0.021
muscle tissue development GO:0060537 1 0.021
axonal fasciculation GO:0007413 79 0.021
negative regulation of rna metabolic process GO:0051253 53 0.021
regulation of nuclear division GO:0051783 115 0.021
nucleobase containing compound biosynthetic process GO:0034654 184 0.021
purine nucleoside triphosphate catabolic process GO:0009146 72 0.021
negative regulation of post embryonic development GO:0048581 208 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.021
nucleoside triphosphate metabolic process GO:0009141 87 0.021
oxoacid metabolic process GO:0043436 47 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.020
regulation of catalytic activity GO:0050790 78 0.020
tissue morphogenesis GO:0048729 65 0.020
nervous system development GO:0007399 253 0.020
Fly
membrane invagination GO:0010324 98 0.020
positive regulation of protein metabolic process GO:0051247 45 0.020
posttranscriptional gene silencing by rna GO:0035194 143 0.020
single organism transport GO:0044765 447 0.019
gene silencing GO:0016458 143 0.019
inductive cell migration GO:0040039 145 0.019
protein complex biogenesis GO:0070271 186 0.019
regulation of developmental growth GO:0048638 389 0.019
regulation of multicellular organism growth GO:0040014 373 0.019
chromosome localization GO:0050000 10 0.018
purine nucleotide metabolic process GO:0006163 95 0.018
regulation of signaling GO:0023051 172 0.018
glycosyl compound metabolic process GO:1901657 100 0.018
purine nucleoside triphosphate metabolic process GO:0009144 87 0.018
nucleobase containing small molecule metabolic process GO:0055086 115 0.018
regulation of biosynthetic process GO:0009889 189 0.018
carbohydrate derivative catabolic process GO:1901136 82 0.018
ion transport GO:0006811 113 0.017
neurological system process GO:0050877 53 0.017
dna replication GO:0006260 15 0.017
neuron projection morphogenesis GO:0048812 114 0.017
ribonucleoside catabolic process GO:0042454 77 0.017
molting cycle GO:0042303 281 0.017
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.017
phosphate containing compound metabolic process GO:0006796 232 0.017
positive regulation of phosphate metabolic process GO:0045937 56 0.016
Fly
engulfment of apoptotic cell GO:0043652 94 0.016
developmental growth GO:0048589 412 0.016
response to oxidative stress GO:0006979 42 0.016
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.016
Fly
atp catabolic process GO:0006200 27 0.016
positive regulation of multicellular organism growth GO:0040018 352 0.016
rna interference GO:0016246 137 0.016
oogenesis GO:0048477 229 0.016
Fly
positive regulation of developmental growth GO:0048639 354 0.016
mitotic sister chromatid segregation GO:0000070 38 0.016
Fly
negative regulation of programmed cell death GO:0043069 19 0.015
ribonucleoside metabolic process GO:0009119 98 0.015
heterocycle biosynthetic process GO:0018130 187 0.015
response to abiotic stimulus GO:0009628 152 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.015
regulation of cellular protein metabolic process GO:0032268 75 0.014
single organism biosynthetic process GO:0044711 91 0.014
regulation of intracellular signal transduction GO:1902531 77 0.014
Human Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.014
cell cycle g1 s phase transition GO:0044843 2 0.014
taxis GO:0042330 128 0.014
cellular response to inorganic substance GO:0071241 3 0.014
ribonucleoside triphosphate catabolic process GO:0009203 72 0.014
covalent chromatin modification GO:0016569 30 0.014
Human Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.014
regulation of programmed cell death GO:0043067 50 0.014
positive regulation of nucleoside metabolic process GO:0045979 28 0.014
regulation of signal transduction GO:0009966 135 0.014
ribonucleotide catabolic process GO:0009261 75 0.013
system process GO:0003008 136 0.013
axonogenesis GO:0007409 102 0.013
cuticle development GO:0042335 100 0.013
dna recombination GO:0006310 19 0.013
purine nucleotide catabolic process GO:0006195 75 0.013
regulation of phosphorus metabolic process GO:0051174 81 0.013
Human Fly
negative regulation of cellular biosynthetic process GO:0031327 65 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
dauer larval development GO:0040024 92 0.013
phosphorylation GO:0016310 116 0.013
positive regulation of kinase activity GO:0033674 19 0.013
organic substance transport GO:0071702 113 0.013
positive regulation of apoptotic process GO:0043065 17 0.013
aromatic compound catabolic process GO:0019439 116 0.013
regulation of protein stability GO:0031647 3 0.013
organic cyclic compound catabolic process GO:1901361 119 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
negative regulation of cell cycle GO:0045786 53 0.012
cell morphogenesis GO:0000902 163 0.012
protein oligomerization GO:0051259 4 0.012
response to external stimulus GO:0009605 289 0.012
phosphorus metabolic process GO:0006793 232 0.012
proteasomal protein catabolic process GO:0010498 20 0.012
amine metabolic process GO:0009308 15 0.012
sensory organ morphogenesis GO:0090596 2 0.012
positive regulation of nucleic acid templated transcription GO:1903508 102 0.012
purine nucleoside catabolic process GO:0006152 75 0.012
regulation of phosphate metabolic process GO:0019220 81 0.012
Human Fly
dna duplex unwinding GO:0032508 3 0.012
macromolecule catabolic process GO:0009057 202 0.012
positive regulation of rna biosynthetic process GO:1902680 102 0.012
negative regulation of rna biosynthetic process GO:1902679 53 0.012
purine ribonucleotide metabolic process GO:0009150 95 0.012
ribonucleoside monophosphate metabolic process GO:0009161 45 0.012
mitotic g2 m transition checkpoint GO:0044818 1 0.011
epithelial cell proliferation GO:0050673 1 0.011
negative regulation of cellular protein metabolic process GO:0032269 27 0.011
digestive system development GO:0055123 122 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.011
nucleoside phosphate catabolic process GO:1901292 77 0.011
spermatogenesis GO:0007283 41 0.011
embryonic body morphogenesis GO:0010172 49 0.011
regulation of cell death GO:0010941 65 0.011
dna packaging GO:0006323 7 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.011
actin filament based process GO:0030029 191 0.011
chromatin organization GO:0006325 32 0.011
Human Fly
ras protein signal transduction GO:0007265 31 0.011
Fly
maintenance of protein localization in organelle GO:0072595 1 0.011
nucleoside phosphate metabolic process GO:0006753 108 0.011
negative regulation of signaling GO:0023057 61 0.011
purine containing compound catabolic process GO:0072523 75 0.011
multicellular organism growth GO:0035264 385 0.011
cellular response to organic substance GO:0071310 119 0.011
positive regulation of growth GO:0045927 369 0.011
intracellular transport GO:0046907 77 0.011
cellular ketone metabolic process GO:0042180 14 0.010
cellular component morphogenesis GO:0032989 318 0.010
negative regulation of cell communication GO:0010648 61 0.010
muscle contraction GO:0006936 43 0.010
establishment of localization in cell GO:0051649 318 0.010

vrk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org