Caenorhabditis elegans

57 known processes

rpn-6.1 (CELE_F57B9.10)

Protein RPN-6.1

rpn-6.1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.898
post embryonic development GO:0009791 2152 0.894
embryo development GO:0009790 3052 0.746
ubiquitin dependent protein catabolic process GO:0006511 32 0.615
sexual reproduction GO:0019953 546 0.603
gamete generation GO:0007276 461 0.545
organ development GO:0048513 1102 0.537
multicellular organism reproduction GO:0032504 819 0.532
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.532
germ cell development GO:0007281 351 0.495
apoptotic process GO:0006915 478 0.465
cellular catabolic process GO:0044248 199 0.458
sex differentiation GO:0007548 909 0.427
cell death GO:0008219 547 0.426
catabolic process GO:0009056 318 0.419
developmental process involved in reproduction GO:0003006 1165 0.417
vulval development GO:0040025 333 0.405
regulation of macromolecule metabolic process GO:0060255 421 0.382
axon development GO:0061564 163 0.382
protein metabolic process GO:0019538 422 0.375
single organism reproductive process GO:0044702 1196 0.349
establishment of localization GO:0051234 1171 0.348
regulation of developmental process GO:0050793 684 0.342
cellular protein catabolic process GO:0044257 37 0.342
multicellular organismal reproductive process GO:0048609 815 0.328
locomotion GO:0040011 1634 0.326
aging GO:0007568 812 0.312
macromolecule catabolic process GO:0009057 202 0.308
vesicle mediated transport GO:0016192 852 0.307
organelle organization GO:0006996 783 0.302
negative regulation of nematode larval development GO:0061064 208 0.294
endocytosis GO:0006897 819 0.280
hermaphrodite genitalia development GO:0040035 734 0.269
modification dependent macromolecule catabolic process GO:0043632 32 0.268
protein catabolic process GO:0030163 162 0.259
cellular protein metabolic process GO:0044267 279 0.252
organic substance catabolic process GO:1901575 294 0.251
death GO:0016265 547 0.251
positive regulation of cellular process GO:0048522 332 0.243
gene expression GO:0010467 412 0.229
regulation of vulval development GO:0040028 248 0.229
regulation of metabolic process GO:0019222 478 0.224
regulation of multicellular organismal process GO:0051239 726 0.220
programmed cell death GO:0012501 500 0.217
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.216
regulation of nematode larval development GO:0061062 260 0.213
transport GO:0006810 1093 0.212
multicellular organismal aging GO:0010259 812 0.202
reproductive system development GO:0061458 850 0.195
growth GO:0040007 562 0.194
regulation of response to stimulus GO:0048583 243 0.191
negative regulation of vulval development GO:0040027 206 0.187
organic substance biosynthetic process GO:1901576 323 0.184
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.182
regulation of cellular metabolic process GO:0031323 305 0.174
cell projection organization GO:0030030 231 0.172
regulation of post embryonic development GO:0048580 260 0.165
determination of adult lifespan GO:0008340 812 0.164
signal transduction GO:0007165 317 0.162
signaling GO:0023052 401 0.159
positive regulation of macromolecule metabolic process GO:0010604 149 0.155
body morphogenesis GO:0010171 620 0.153
cytoskeleton organization GO:0007010 339 0.152
receptor mediated endocytosis GO:0006898 715 0.151
cell cycle GO:0007049 526 0.149
microtubule based process GO:0007017 182 0.144
multicellular organismal reproductive behavior GO:0033057 384 0.140
regulation of growth GO:0040008 409 0.139
small gtpase mediated signal transduction GO:0007264 32 0.138
proteolysis GO:0006508 61 0.134
proteasomal protein catabolic process GO:0010498 20 0.131
reproductive structure development GO:0048608 850 0.131
regulation of catabolic process GO:0009894 57 0.128
oviposition GO:0018991 364 0.127
gonad development GO:0008406 840 0.125
post embryonic organ development GO:0048569 336 0.125
ras protein signal transduction GO:0007265 31 0.123
oocyte axis specification GO:0007309 2 0.122
cellular component movement GO:0006928 388 0.122
cellular component biogenesis GO:0044085 297 0.122
regulation of primary metabolic process GO:0080090 292 0.121
reproductive behavior GO:0019098 387 0.120
regulation of biological quality GO:0065008 741 0.120
generation of neurons GO:0048699 235 0.119
regulation of developmental growth GO:0048638 389 0.119
neuron differentiation GO:0030182 217 0.118
ribonucleoside triphosphate metabolic process GO:0009199 87 0.117
mitotic cell cycle process GO:1903047 194 0.113
positive regulation of cellular metabolic process GO:0031325 178 0.112
cell migration GO:0016477 306 0.110
fertilization GO:0009566 63 0.107
macromolecule biosynthetic process GO:0009059 250 0.106
regulation of cellular catabolic process GO:0031329 51 0.104
behavior GO:0007610 527 0.102
nucleobase containing small molecule metabolic process GO:0055086 115 0.101
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.099
organophosphate metabolic process GO:0019637 125 0.099
organophosphate catabolic process GO:0046434 81 0.098
cellular macromolecule catabolic process GO:0044265 73 0.097
single fertilization GO:0007338 61 0.097
phosphorus metabolic process GO:0006793 232 0.097
regulation of multicellular organismal development GO:2000026 317 0.097
single organism signaling GO:0044700 401 0.094
cellular protein complex assembly GO:0043623 178 0.093
organelle fission GO:0048285 363 0.093
protein complex subunit organization GO:0071822 280 0.093
cellular macromolecule biosynthetic process GO:0034645 247 0.093
multi organism reproductive process GO:0044703 867 0.092
female gamete generation GO:0007292 254 0.092
single organism organelle organization GO:1902589 501 0.089
regulation of cellular biosynthetic process GO:0031326 189 0.089
single organism localization GO:1902578 518 0.088
cell motility GO:0048870 313 0.087
cell part morphogenesis GO:0032990 152 0.085
neurogenesis GO:0022008 236 0.085
phosphate containing compound metabolic process GO:0006796 232 0.082
neuron development GO:0048666 199 0.082
regulation of small gtpase mediated signal transduction GO:0051056 41 0.080
biosynthetic process GO:0009058 323 0.080
nervous system development GO:0007399 253 0.080
regulation of rna biosynthetic process GO:2001141 165 0.079
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.079
macromolecule localization GO:0033036 771 0.078
developmental growth GO:0048589 412 0.078
single organism catabolic process GO:0044712 129 0.074
nucleobase containing compound metabolic process GO:0006139 406 0.073
positive regulation of metabolic process GO:0009893 187 0.072
development of primary sexual characteristics GO:0045137 840 0.072
regulation of organelle organization GO:0033043 164 0.071
nucleic acid metabolic process GO:0090304 299 0.071
maintenance of location GO:0051235 580 0.070
single organism transport GO:0044765 447 0.070
response to organic substance GO:0010033 131 0.069
macromolecular complex subunit organization GO:0043933 320 0.067
regulation of ras protein signal transduction GO:0046578 41 0.066
regulation of cell communication GO:0010646 176 0.066
regulation of signal transduction GO:0009966 135 0.066
positive regulation of rna biosynthetic process GO:1902680 102 0.066
macromolecule modification GO:0043412 218 0.065
response to abiotic stimulus GO:0009628 152 0.065
regulation of multicellular organism growth GO:0040014 373 0.065
muscle structure development GO:0061061 191 0.065
positive regulation of growth GO:0045927 369 0.064
nucleobase containing compound catabolic process GO:0034655 114 0.063
positive regulation of neurogenesis GO:0050769 4 0.063
posttranscriptional regulation of gene expression GO:0010608 166 0.063
lipid localization GO:0010876 573 0.062
heterocycle catabolic process GO:0046700 119 0.062
protein modification process GO:0036211 207 0.061
purine ribonucleotide metabolic process GO:0009150 95 0.061
meiotic cell cycle GO:0051321 335 0.061
lipid storage GO:0019915 565 0.060
cell division GO:0051301 262 0.060
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 5 0.059
cell development GO:0048468 696 0.059
spindle organization GO:0007051 92 0.058
small molecule metabolic process GO:0044281 186 0.058
negative regulation of post embryonic development GO:0048581 208 0.058
response to external stimulus GO:0009605 289 0.057
negative regulation of biological process GO:0048519 567 0.057
organic cyclic compound catabolic process GO:1901361 119 0.057
receptor metabolic process GO:0043112 6 0.057
negative regulation of developmental process GO:0051093 227 0.055
cell surface receptor signaling pathway GO:0007166 149 0.055
regulation of meiotic cell cycle GO:0051445 136 0.055
regulation of catalytic activity GO:0050790 78 0.055
oocyte construction GO:0007308 2 0.054
regulation of signaling GO:0023051 172 0.054
regulation of cellular component organization GO:0051128 248 0.054
oogenesis GO:0048477 229 0.054
purine nucleotide metabolic process GO:0006163 95 0.052
cell projection morphogenesis GO:0048858 148 0.051
multi organism behavior GO:0051705 389 0.051
protein complex biogenesis GO:0070271 186 0.051
nucleoside catabolic process GO:0009164 78 0.051
organonitrogen compound metabolic process GO:1901564 151 0.050
meiotic nuclear division GO:0007126 300 0.050
cell cycle process GO:0022402 482 0.049
positive regulation of multicellular organism growth GO:0040018 352 0.049
positive regulation of developmental process GO:0051094 408 0.048
negative regulation of metabolic process GO:0009892 240 0.047
positive regulation of catalytic activity GO:0043085 59 0.047
positive regulation of developmental growth GO:0048639 354 0.047
meiotic chromosome segregation GO:0045132 139 0.046
nucleoside phosphate metabolic process GO:0006753 108 0.046
regulation of neuron differentiation GO:0045664 40 0.045
nucleoside metabolic process GO:0009116 99 0.045
positive regulation of multicellular organismal process GO:0051240 417 0.045
multicellular organism growth GO:0035264 385 0.045
negative regulation of cellular process GO:0048523 239 0.044
axis specification GO:0009798 23 0.044
male gamete generation GO:0048232 41 0.044
macromolecular complex assembly GO:0065003 193 0.043
purine containing compound metabolic process GO:0072521 95 0.043
modification dependent protein catabolic process GO:0019941 32 0.043
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.043
actin cytoskeleton organization GO:0030036 184 0.042
molting cycle GO:0042303 281 0.042
regulation of phosphate metabolic process GO:0019220 81 0.041
anatomical structure formation involved in morphogenesis GO:0048646 250 0.041
regulation of protein metabolic process GO:0051246 81 0.040
cellular response to chemical stimulus GO:0070887 129 0.040
protein complex assembly GO:0006461 186 0.040
nucleotide metabolic process GO:0009117 108 0.039
organelle localization GO:0051640 127 0.038
cellular protein modification process GO:0006464 207 0.038
cellular response to stress GO:0033554 162 0.038
establishment of localization in cell GO:0051649 318 0.038
mitotic spindle organization GO:0007052 81 0.038
purine ribonucleoside metabolic process GO:0046128 92 0.037
negative regulation of multicellular organismal process GO:0051241 236 0.037
cellular component morphogenesis GO:0032989 318 0.037
aromatic compound catabolic process GO:0019439 116 0.037
digestive system development GO:0055123 122 0.037
establishment of organelle localization GO:0051656 123 0.036
phagocytosis GO:0006909 115 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.034
neuron projection development GO:0031175 187 0.034
localization of cell GO:0051674 313 0.034
rna metabolic process GO:0016070 228 0.034
purine nucleoside triphosphate metabolic process GO:0009144 87 0.033
pronuclear migration GO:0035046 51 0.032
purine nucleoside triphosphate catabolic process GO:0009146 72 0.032
ribonucleoside metabolic process GO:0009119 98 0.032
organelle assembly GO:0070925 214 0.032
purine nucleoside catabolic process GO:0006152 75 0.032
neuron projection guidance GO:0097485 82 0.031
membrane organization GO:0061024 135 0.031
regulation of nervous system development GO:0051960 41 0.031
nucleobase containing compound biosynthetic process GO:0034654 184 0.031
genitalia development GO:0048806 741 0.030
regulation of cellular protein metabolic process GO:0032268 75 0.030
ribonucleotide metabolic process GO:0009259 99 0.030
gtp catabolic process GO:0006184 46 0.030
mitotic g2 m transition checkpoint GO:0044818 1 0.030
intracellular receptor signaling pathway GO:0030522 2 0.030
purine ribonucleotide catabolic process GO:0009154 75 0.029
actin filament based process GO:0030029 191 0.029
protein localization GO:0008104 205 0.028
regulation of nitrogen compound metabolic process GO:0051171 222 0.028
guanosine containing compound metabolic process GO:1901068 49 0.028
ribonucleotide catabolic process GO:0009261 75 0.028
carbohydrate derivative metabolic process GO:1901135 141 0.028
chromosome segregation GO:0007059 180 0.028
regulation of nuclear division GO:0051783 115 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.028
multi multicellular organism process GO:0044706 390 0.028
positive regulation of cellular catabolic process GO:0031331 35 0.028
carbohydrate derivative catabolic process GO:1901136 82 0.027
negative regulation of macromolecule metabolic process GO:0010605 229 0.027
regulation of cell proliferation GO:0042127 105 0.027
positive regulation of phosphorylation GO:0042327 27 0.027
negative regulation of cellular protein metabolic process GO:0032269 27 0.026
cellular biosynthetic process GO:0044249 315 0.026
negative regulation of gene expression epigenetic GO:0045814 2 0.026
digestive tract development GO:0048565 122 0.026
cell morphogenesis GO:0000902 163 0.026
multi organism reproductive behavior GO:0044705 387 0.026
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.026
cellular localization GO:0051641 360 0.026
purine nucleotide catabolic process GO:0006195 75 0.026
cellular response to dna damage stimulus GO:0006974 41 0.025
spermatogenesis GO:0007283 41 0.025
regulation of cell differentiation GO:0045595 81 0.025
regulation of multi organism process GO:0043900 69 0.025
intracellular signal transduction GO:0035556 96 0.024
regulation of cell division GO:0051302 142 0.024
meiotic cell cycle process GO:1903046 170 0.024
response to chemical GO:0042221 356 0.024
positive regulation of hydrolase activity GO:0051345 38 0.023
negative regulation of cellular metabolic process GO:0031324 95 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 5 0.023
regulation of intracellular signal transduction GO:1902531 77 0.023
negative regulation of protein metabolic process GO:0051248 27 0.023
positive regulation of cellular component organization GO:0051130 34 0.023
oxidation reduction process GO:0055114 59 0.023
muscle cell differentiation GO:0042692 171 0.022
purine nucleoside metabolic process GO:0042278 92 0.022
protein modification by small protein conjugation or removal GO:0070647 40 0.022
regulation of nucleic acid templated transcription GO:1903506 165 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 5 0.022
negative regulation of chromosome segregation GO:0051985 4 0.022
aromatic compound biosynthetic process GO:0019438 192 0.022
organonitrogen compound catabolic process GO:1901565 90 0.021
regulation of gene expression GO:0010468 366 0.021
oxoacid metabolic process GO:0043436 47 0.021
ribonucleoside triphosphate catabolic process GO:0009203 72 0.021
chromosome organization GO:0051276 104 0.021
regulation of molecular function GO:0065009 89 0.020
transcription from rna polymerase ii promoter GO:0006366 149 0.020
cellular macromolecular complex assembly GO:0034622 184 0.020
taxis GO:0042330 128 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.020
glycosyl compound metabolic process GO:1901657 100 0.020
nucleoside triphosphate metabolic process GO:0009141 87 0.020
regulation of cell development GO:0060284 49 0.020
glycosyl compound catabolic process GO:1901658 79 0.020
organic acid metabolic process GO:0006082 47 0.019
pattern specification process GO:0007389 59 0.019
regulation of hydrolase activity GO:0051336 45 0.019
apoptotic cell clearance GO:0043277 111 0.019
cellular component assembly GO:0022607 293 0.019
axon guidance GO:0007411 82 0.019
cell morphogenesis involved in differentiation GO:0000904 112 0.019
rna biosynthetic process GO:0032774 169 0.019
positive regulation of molecular function GO:0044093 61 0.018
nucleic acid templated transcription GO:0097659 169 0.018
nucleotide catabolic process GO:0009166 77 0.018
negative regulation of cell cycle GO:0045786 53 0.018
regulation of mitosis GO:0007088 18 0.018
guanosine containing compound catabolic process GO:1901069 48 0.018
single organism carbohydrate metabolic process GO:0044723 29 0.018
regulation of neurogenesis GO:0050767 40 0.018
nuclear migration GO:0007097 54 0.018
tissue development GO:0009888 112 0.017
protein modification by small protein conjugation GO:0032446 31 0.017
negative regulation of gene expression GO:0010629 217 0.017
response to endogenous stimulus GO:0009719 33 0.017
nucleoside triphosphate catabolic process GO:0009143 72 0.017
carboxylic acid metabolic process GO:0019752 34 0.017
regulation of biosynthetic process GO:0009889 189 0.017
regulation of transcription dna templated GO:0006355 164 0.017
positive regulation of catabolic process GO:0009896 38 0.017
positive regulation of nucleotide catabolic process GO:0030813 28 0.017
response to mechanical stimulus GO:0009612 28 0.017
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.017
regulation of phosphorus metabolic process GO:0051174 81 0.017
regulation of mitotic cell cycle GO:0007346 76 0.017
positive regulation of intracellular signal transduction GO:1902533 24 0.017
embryonic morphogenesis GO:0048598 152 0.016
positive regulation of nucleoside metabolic process GO:0045979 28 0.016
secretion GO:0046903 147 0.016
regeneration GO:0031099 4 0.016
ribose phosphate metabolic process GO:0019693 99 0.016
regulation of nucleotide metabolic process GO:0006140 37 0.016
mitotic nuclear envelope reassembly GO:0007084 3 0.016
sensory organ morphogenesis GO:0090596 2 0.016
positive regulation of phosphate metabolic process GO:0045937 56 0.016
cell proliferation GO:0008283 116 0.016
membrane invagination GO:0010324 98 0.016
tube development GO:0035295 126 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.015
regulation of localization GO:0032879 194 0.015
regulation of cell cycle process GO:0010564 145 0.015
tissue morphogenesis GO:0048729 65 0.015
ribonucleoside catabolic process GO:0042454 77 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.014
gene silencing GO:0016458 143 0.014
negative regulation of cell communication GO:0010648 61 0.014
positive regulation of gene expression GO:0010628 112 0.014
purine ribonucleoside catabolic process GO:0046130 75 0.014
neuron projection morphogenesis GO:0048812 114 0.014
regulation of meiosis GO:0040020 94 0.014
regionalization GO:0003002 31 0.014
single organism biosynthetic process GO:0044711 91 0.014
organic cyclic compound biosynthetic process GO:1901362 195 0.013
positive regulation of neuron differentiation GO:0045666 4 0.013
phagocytosis engulfment GO:0006911 98 0.013
centrosomal and pronuclear rotation GO:0035047 6 0.013
regulation of protein catabolic process GO:0042176 13 0.013
regulation of rna metabolic process GO:0051252 173 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
engulfment of apoptotic cell GO:0043652 94 0.013
heterocycle biosynthetic process GO:0018130 187 0.013
golgi vesicle transport GO:0048193 3 0.013
cell cell signaling GO:0007267 118 0.013
positive regulation of nucleotide metabolic process GO:0045981 28 0.012
dendrite development GO:0016358 42 0.012
response to wounding GO:0009611 4 0.012
negative regulation of mitotic sister chromatid segregation GO:0033048 4 0.012
regulation of protein stability GO:0031647 3 0.012
positive regulation of phosphorus metabolic process GO:0010562 56 0.012
regulation of macromolecule biosynthetic process GO:0010556 189 0.012
regulation of purine nucleotide metabolic process GO:1900542 37 0.012
cell growth GO:0016049 44 0.012
positive regulation of biosynthetic process GO:0009891 109 0.012
cellular amine metabolic process GO:0044106 15 0.012
cellular response to organic substance GO:0071310 119 0.012
positive regulation of cellular biosynthetic process GO:0031328 109 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.012
muscle organ morphogenesis GO:0048644 4 0.011
positive regulation of transcription dna templated GO:0045893 102 0.011
positive regulation of rna metabolic process GO:0051254 103 0.011
purine containing compound catabolic process GO:0072523 75 0.011
generation of precursor metabolites and energy GO:0006091 18 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 4 0.011
regulation of nucleotide catabolic process GO:0030811 35 0.011
nematode male tail tip morphogenesis GO:0045138 77 0.011
cell cycle g1 s phase transition GO:0044843 2 0.011
translation GO:0006412 37 0.011
striated muscle cell differentiation GO:0051146 158 0.011
maintenance of protein location GO:0045185 15 0.011
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
axonogenesis GO:0007409 102 0.011
regulation of behavior GO:0050795 97 0.010
negative regulation of signaling GO:0023057 61 0.010
cell cycle phase transition GO:0044770 19 0.010
regulation of purine nucleotide catabolic process GO:0033121 35 0.010
protein ubiquitination GO:0016567 25 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.010
posttranscriptional gene silencing GO:0016441 143 0.010
attachment of spindle microtubules to kinetochore GO:0008608 8 0.010
posttranscriptional gene silencing by rna GO:0035194 143 0.010
digestive tract morphogenesis GO:0048546 76 0.010

rpn-6.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.014
congenital muscular dystrophy DOID:0050557 0 0.014
muscular disease DOID:0080000 0 0.014
muscular dystrophy DOID:9884 0 0.014
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
muscle tissue disease DOID:66 0 0.014
disease of metabolism DOID:0014667 0 0.014
nervous system disease DOID:863 0 0.012
inherited metabolic disorder DOID:655 0 0.011