Caenorhabditis elegans

51 known processes

pbrm-1 (CELE_C26C6.1)

Protein PBRM-1

pbrm-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.909
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.867
Fly
embryo development GO:0009790 3052 0.867
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.843
Fly
organ development GO:0048513 1102 0.820
establishment of localization GO:0051234 1171 0.700
gonad development GO:0008406 840 0.673
reproductive system development GO:0061458 850 0.643
regulation of multicellular organismal development GO:2000026 317 0.640
locomotion GO:0040011 1634 0.639
transport GO:0006810 1093 0.629
positive regulation of transcription dna templated GO:0045893 102 0.589
Fly
reproductive structure development GO:0048608 850 0.585
positive regulation of gene expression GO:0010628 112 0.578
Fly
regulation of primary metabolic process GO:0080090 292 0.547
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.519
post embryonic development GO:0009791 2152 0.517
hermaphrodite genitalia development GO:0040035 734 0.479
regulation of rna metabolic process GO:0051252 173 0.460
Fly
genitalia development GO:0048806 741 0.448
negative regulation of vulval development GO:0040027 206 0.447
cell motility GO:0048870 313 0.436
sex differentiation GO:0007548 909 0.422
regulation of rna biosynthetic process GO:2001141 165 0.405
Fly
positive regulation of rna metabolic process GO:0051254 103 0.403
Fly
heterocycle biosynthetic process GO:0018130 187 0.403
Fly
regulation of multicellular organismal process GO:0051239 726 0.389
positive regulation of metabolic process GO:0009893 187 0.386
Fly
regulation of metabolic process GO:0019222 478 0.382
Fly
regulation of vulval development GO:0040028 248 0.378
positive regulation of nucleic acid templated transcription GO:1903508 102 0.375
Fly
regulation of nematode larval development GO:0061062 260 0.372
post embryonic organ development GO:0048569 336 0.369
development of primary sexual characteristics GO:0045137 840 0.364
macromolecule biosynthetic process GO:0009059 250 0.364
Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.363
Fly
regulation of cellular metabolic process GO:0031323 305 0.359
Fly
aromatic compound biosynthetic process GO:0019438 192 0.358
Fly
single organism organelle organization GO:1902589 501 0.347
neuron projection development GO:0031175 187 0.345
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.344
Fly
macromolecular complex subunit organization GO:0043933 320 0.342
protein complex subunit organization GO:0071822 280 0.342
vulval development GO:0040025 333 0.341
negative regulation of post embryonic development GO:0048581 208 0.331
negative regulation of biological process GO:0048519 567 0.313
transcription dna templated GO:0006351 168 0.310
Fly
gene expression GO:0010467 412 0.307
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.296
Fly
receptor mediated endocytosis GO:0006898 715 0.289
regulation of developmental process GO:0050793 684 0.285
cell migration GO:0016477 306 0.280
vesicle mediated transport GO:0016192 852 0.277
neuron differentiation GO:0030182 217 0.268
nervous system development GO:0007399 253 0.254
organic cyclic compound biosynthetic process GO:1901362 195 0.243
Fly
cellular biosynthetic process GO:0044249 315 0.242
Fly
neurogenesis GO:0022008 236 0.242
nucleoside catabolic process GO:0009164 78 0.241
endocytosis GO:0006897 819 0.239
regulation of biosynthetic process GO:0009889 189 0.233
Fly
regulation of nitrogen compound metabolic process GO:0051171 222 0.220
Fly
single organism signaling GO:0044700 401 0.220
single organism reproductive process GO:0044702 1196 0.214
positive regulation of biosynthetic process GO:0009891 109 0.210
Fly
rna biosynthetic process GO:0032774 169 0.204
Fly
positive regulation of cellular metabolic process GO:0031325 178 0.195
Fly
regulation of transcription dna templated GO:0006355 164 0.190
Fly
organelle organization GO:0006996 783 0.184
immune response GO:0006955 192 0.172
negative regulation of nematode larval development GO:0061064 208 0.165
localization of cell GO:0051674 313 0.164
regulation of post embryonic development GO:0048580 260 0.162
negative regulation of macromolecule metabolic process GO:0010605 229 0.158
Fly
ribonucleoside triphosphate metabolic process GO:0009199 87 0.156
transcription from rna polymerase ii promoter GO:0006366 149 0.156
nucleoside triphosphate catabolic process GO:0009143 72 0.152
multicellular organismal reproductive process GO:0048609 815 0.151
Fly
positive regulation of cellular biosynthetic process GO:0031328 109 0.149
Fly
cellular catabolic process GO:0044248 199 0.144
regulation of nucleic acid templated transcription GO:1903506 165 0.144
Fly
cellular component movement GO:0006928 388 0.142
single organism transport GO:0044765 447 0.139
nucleic acid metabolic process GO:0090304 299 0.139
Fly
regulation of gene expression GO:0010468 366 0.138
Fly
neuron development GO:0048666 199 0.137
regulation of cellular biosynthetic process GO:0031326 189 0.136
Fly
purine nucleotide catabolic process GO:0006195 75 0.132
microtubule based process GO:0007017 182 0.130
cytoskeleton organization GO:0007010 339 0.129
meiotic nuclear division GO:0007126 300 0.128
nucleotide catabolic process GO:0009166 77 0.128
positive regulation of rna biosynthetic process GO:1902680 102 0.127
Fly
negative regulation of cellular process GO:0048523 239 0.124
Human Fly
rna metabolic process GO:0016070 228 0.123
Fly
purine nucleoside triphosphate metabolic process GO:0009144 87 0.123
cellular component biogenesis GO:0044085 297 0.122
Fly
developmental process involved in reproduction GO:0003006 1165 0.121
cell cycle process GO:0022402 482 0.121
intracellular signal transduction GO:0035556 96 0.119
regulation of cell motility GO:2000145 57 0.118
regulation of locomotion GO:0040012 161 0.115
cell projection organization GO:0030030 231 0.113
multicellular organism reproduction GO:0032504 819 0.112
Fly
purine nucleotide metabolic process GO:0006163 95 0.112
negative regulation of developmental process GO:0051093 227 0.110
aging GO:0007568 812 0.109
negative regulation of multicellular organismal process GO:0051241 236 0.107
organic substance catabolic process GO:1901575 294 0.107
gene silencing GO:0016458 143 0.107
Fly
regulation of cell migration GO:0030334 55 0.106
cell projection morphogenesis GO:0048858 148 0.105
regulation of signaling GO:0023051 172 0.104
head development GO:0060322 1 0.103
positive regulation of macromolecule metabolic process GO:0010604 149 0.100
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.099
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.099
ribonucleoside metabolic process GO:0009119 98 0.098
regulation of macromolecule metabolic process GO:0060255 421 0.098
Fly
ribose phosphate metabolic process GO:0019693 99 0.098
regulation of macromolecule biosynthetic process GO:0010556 189 0.097
Fly
determination of adult lifespan GO:0008340 812 0.097
carbohydrate derivative metabolic process GO:1901135 141 0.097
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.095
Fly
positive regulation of developmental process GO:0051094 408 0.095
organic substance biosynthetic process GO:1901576 323 0.095
Fly
single organism localization GO:1902578 518 0.094
ribonucleotide metabolic process GO:0009259 99 0.092
macromolecule localization GO:0033036 771 0.090
negative regulation of metabolic process GO:0009892 240 0.089
Fly
ribonucleoside catabolic process GO:0042454 77 0.087
multi organism reproductive process GO:0044703 867 0.087
Fly
purine ribonucleotide catabolic process GO:0009154 75 0.086
sexual reproduction GO:0019953 546 0.086
Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.085
Fly
purine containing compound metabolic process GO:0072521 95 0.085
cell cycle GO:0007049 526 0.081
nucleobase containing compound metabolic process GO:0006139 406 0.081
Fly
signaling GO:0023052 401 0.081
regulation of cellular component movement GO:0051270 62 0.080
cellular component morphogenesis GO:0032989 318 0.080
Fly
rna interference GO:0016246 137 0.080
organophosphate metabolic process GO:0019637 125 0.079
ribonucleotide catabolic process GO:0009261 75 0.078
mitotic cell cycle process GO:1903047 194 0.077
purine nucleoside metabolic process GO:0042278 92 0.077
cellular localization GO:0051641 360 0.077
heterocycle catabolic process GO:0046700 119 0.076
regulation of response to stimulus GO:0048583 243 0.076
nucleobase containing small molecule metabolic process GO:0055086 115 0.074
purine ribonucleotide metabolic process GO:0009150 95 0.074
regulation of cell cycle GO:0051726 194 0.073
cell development GO:0048468 696 0.072
Fly
cellular response to stress GO:0033554 162 0.071
purine ribonucleoside catabolic process GO:0046130 75 0.071
nucleobase containing compound catabolic process GO:0034655 114 0.070
nucleic acid templated transcription GO:0097659 169 0.070
Fly
gamete generation GO:0007276 461 0.070
Fly
purine nucleoside triphosphate catabolic process GO:0009146 72 0.069
maintenance of location GO:0051235 580 0.068
cellular macromolecular complex assembly GO:0034622 184 0.067
meiotic cell cycle process GO:1903046 170 0.066
organophosphate catabolic process GO:0046434 81 0.066
response to biotic stimulus GO:0009607 101 0.065
glycosyl compound metabolic process GO:1901657 100 0.065
organonitrogen compound metabolic process GO:1901564 151 0.065
purine containing compound catabolic process GO:0072523 75 0.064
multicellular organismal aging GO:0010259 812 0.064
cellular macromolecule biosynthetic process GO:0034645 247 0.063
Fly
purine nucleoside catabolic process GO:0006152 75 0.063
dendrite development GO:0016358 42 0.063
ribonucleoside monophosphate metabolic process GO:0009161 45 0.062
positive regulation of cellular process GO:0048522 332 0.062
Fly
cellular component assembly GO:0022607 293 0.062
Fly
ribonucleoside triphosphate catabolic process GO:0009203 72 0.062
lipid localization GO:0010876 573 0.062
multi multicellular organism process GO:0044706 390 0.061
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.061
Fly
oviposition GO:0018991 364 0.061
tube development GO:0035295 126 0.059
aromatic compound catabolic process GO:0019439 116 0.059
posttranscriptional gene silencing by rna GO:0035194 143 0.059
small molecule metabolic process GO:0044281 186 0.058
lipid storage GO:0019915 565 0.058
regulation of biological quality GO:0065008 741 0.057
biosynthetic process GO:0009058 323 0.057
Fly
negative regulation of transcription dna templated GO:0045892 53 0.057
Fly
guanosine containing compound metabolic process GO:1901068 49 0.056
negative regulation of nucleic acid templated transcription GO:1903507 53 0.054
Fly
small gtpase mediated signal transduction GO:0007264 32 0.054
single organism catabolic process GO:0044712 129 0.054
generation of neurons GO:0048699 235 0.053
organonitrogen compound catabolic process GO:1901565 90 0.052
oxoacid metabolic process GO:0043436 47 0.051
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.051
Fly
regulation of mitotic cell cycle GO:0007346 76 0.051
positive regulation of vulval development GO:0040026 52 0.051
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.051
carbohydrate derivative catabolic process GO:1901136 82 0.050
regulation of cell differentiation GO:0045595 81 0.049
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.049
Fly
body morphogenesis GO:0010171 620 0.049
cellular nitrogen compound catabolic process GO:0044270 119 0.048
protein complex assembly GO:0006461 186 0.048
muscle cell development GO:0055001 158 0.047
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.047
regulation of signal transduction GO:0009966 135 0.046
positive regulation of signaling GO:0023056 66 0.045
molting cycle GO:0042303 281 0.045
nucleoside metabolic process GO:0009116 99 0.045
regulation of gene expression epigenetic GO:0040029 163 0.045
Fly
muscle structure development GO:0061061 191 0.044
positive regulation of epithelial cell proliferation GO:0050679 1 0.044
negative regulation of rna metabolic process GO:0051253 53 0.044
Fly
macromolecular complex assembly GO:0065003 193 0.044
nucleoside phosphate catabolic process GO:1901292 77 0.043
developmental growth GO:0048589 412 0.043
nucleoside phosphate metabolic process GO:0006753 108 0.043
regulation of cellular component organization GO:0051128 248 0.042
nucleotide metabolic process GO:0009117 108 0.042
multicellular organismal reproductive behavior GO:0033057 384 0.041
regulation of meiotic cell cycle GO:0051445 136 0.040
negative regulation of cellular biosynthetic process GO:0031327 65 0.040
Fly
histone modification GO:0016570 30 0.040
positive regulation of neurogenesis GO:0050769 4 0.039
cellular protein complex assembly GO:0043623 178 0.039
regulation of localization GO:0032879 194 0.038
protein complex biogenesis GO:0070271 186 0.038
response to external biotic stimulus GO:0043207 101 0.038
actin cytoskeleton organization GO:0030036 184 0.037
signal transduction GO:0007165 317 0.037
neuron projection morphogenesis GO:0048812 114 0.036
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.036
gastrulation GO:0007369 58 0.036
embryonic morphogenesis GO:0048598 152 0.036
regulation of cell cycle process GO:0010564 145 0.035
programmed cell death GO:0012501 500 0.034
anatomical structure formation involved in morphogenesis GO:0048646 250 0.034
Fly
striated muscle cell differentiation GO:0051146 158 0.034
striated muscle myosin thick filament assembly GO:0071688 138 0.034
purine ribonucleoside metabolic process GO:0046128 92 0.034
chromatin remodeling GO:0006338 2 0.032
positive regulation of signal transduction GO:0009967 40 0.032
nucleoside triphosphate metabolic process GO:0009141 87 0.032
striated muscle cell development GO:0055002 157 0.032
muscle tissue development GO:0060537 1 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.031
organic acid metabolic process GO:0006082 47 0.031
positive regulation of intracellular signal transduction GO:1902533 24 0.031
carboxylic acid metabolic process GO:0019752 34 0.031
epithelial cell proliferation GO:0050673 1 0.030
muscle cell differentiation GO:0042692 171 0.030
digestive tract morphogenesis GO:0048546 76 0.030
posttranscriptional gene silencing GO:0016441 143 0.030
phosphate containing compound metabolic process GO:0006796 232 0.030
ribonucleoprotein complex assembly GO:0022618 4 0.029
regulation of embryonic development GO:0045995 16 0.029
positive regulation of cell migration GO:0030335 3 0.029
negative regulation of biosynthetic process GO:0009890 65 0.029
Fly
cell fate commitment GO:0045165 139 0.029
digestive tract development GO:0048565 122 0.029
positive regulation of post embryonic development GO:0048582 54 0.028
tube morphogenesis GO:0035239 79 0.028
sensory organ morphogenesis GO:0090596 2 0.028
apoptotic process GO:0006915 478 0.028
response to other organism GO:0051707 101 0.028
negative regulation of gene expression GO:0010629 217 0.028
Fly
cuticle development GO:0042335 100 0.027
cell morphogenesis involved in differentiation GO:0000904 112 0.027
regulation of cell communication GO:0010646 176 0.027
organic cyclic compound catabolic process GO:1901361 119 0.027
cellular macromolecule localization GO:0070727 75 0.027
defense response GO:0006952 296 0.026
multi organism reproductive behavior GO:0044705 387 0.026
cell surface receptor signaling pathway GO:0007166 149 0.026
cellular component assembly involved in morphogenesis GO:0010927 183 0.026
Fly
regionalization GO:0003002 31 0.026
digestive system development GO:0055123 122 0.026
organ morphogenesis GO:0009887 67 0.025
Fly
collagen and cuticulin based cuticle development GO:0040002 99 0.025
regulation of meiosis GO:0040020 94 0.024
negative regulation of rna biosynthetic process GO:1902679 53 0.024
Fly
phagocytosis engulfment GO:0006911 98 0.024
organelle fission GO:0048285 363 0.024
cell part morphogenesis GO:0032990 152 0.024
actin filament based process GO:0030029 191 0.024
meiotic cell cycle GO:0051321 335 0.024
amine metabolic process GO:0009308 15 0.024
tissue development GO:0009888 112 0.023
Fly
chromatin modification GO:0016568 32 0.023
growth GO:0040007 562 0.023
secretion GO:0046903 147 0.023
posttranscriptional regulation of gene expression GO:0010608 166 0.023
reproductive behavior GO:0019098 387 0.023
catabolic process GO:0009056 318 0.022
response to bacterium GO:0009617 86 0.022
gene silencing by rna GO:0031047 143 0.022
cellular response to dna damage stimulus GO:0006974 41 0.022
establishment of organelle localization GO:0051656 123 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.022
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.022
Fly
dna templated transcription elongation GO:0006354 1 0.022
dna metabolic process GO:0006259 74 0.022
organelle assembly GO:0070925 214 0.021
multi organism behavior GO:0051705 389 0.021
spindle organization GO:0007051 92 0.020
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.020
chromatin organization GO:0006325 32 0.020
regulation of intracellular signal transduction GO:1902531 77 0.020
myosin filament assembly GO:0031034 138 0.020
chromosome segregation GO:0007059 180 0.020
organelle localization GO:0051640 127 0.020
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.020
phosphorylation GO:0016310 116 0.020
protein oligomerization GO:0051259 4 0.019
protein metabolic process GO:0019538 422 0.019
single organism biosynthetic process GO:0044711 91 0.019
cellular response to chemical stimulus GO:0070887 129 0.018
positive regulation of cell differentiation GO:0045597 8 0.018
chromatin assembly or disassembly GO:0006333 1 0.018
positive regulation of growth GO:0045927 369 0.018
regulation of multicellular organism growth GO:0040014 373 0.018
regulation of catalytic activity GO:0050790 78 0.018
regulation of phosphate metabolic process GO:0019220 81 0.018
phagocytosis GO:0006909 115 0.018
protein dna complex subunit organization GO:0071824 7 0.018
mrna metabolic process GO:0016071 31 0.018
regulation of epithelial cell proliferation GO:0050678 1 0.018
response to external stimulus GO:0009605 289 0.017
regulation of molecular function GO:0065009 89 0.017
multicellular organism growth GO:0035264 385 0.017
organic substance transport GO:0071702 113 0.017
inductive cell migration GO:0040039 145 0.017
nucleoside monophosphate metabolic process GO:0009123 46 0.017
regulation of cell proliferation GO:0042127 105 0.017
Human
regulation of organelle organization GO:0033043 164 0.017
cell cycle g1 s phase transition GO:0044843 2 0.017
actomyosin structure organization GO:0031032 154 0.017
tissue morphogenesis GO:0048729 65 0.017
chromosome organization GO:0051276 104 0.017
g1 s transition of mitotic cell cycle GO:0000082 2 0.017
glycosyl compound catabolic process GO:1901658 79 0.016
system process GO:0003008 136 0.016
myofibril assembly GO:0030239 154 0.016
regulation of growth GO:0040008 409 0.016
cellular protein metabolic process GO:0044267 279 0.016
transmembrane transport GO:0055085 110 0.016
innate immune response GO:0045087 190 0.016
meiotic chromosome segregation GO:0045132 139 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
canonical wnt signaling pathway GO:0060070 3 0.015
cell division GO:0051301 262 0.015
myosin filament organization GO:0031033 138 0.015
regulation of catabolic process GO:0009894 57 0.015
negative regulation of cellular metabolic process GO:0031324 95 0.015
Fly
establishment of localization in cell GO:0051649 318 0.014
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.014
cellular response to nutrient levels GO:0031669 13 0.014
cell morphogenesis GO:0000902 163 0.014
atp metabolic process GO:0046034 42 0.014
protein modification process GO:0036211 207 0.014
response to wounding GO:0009611 4 0.014
regulation of multi organism process GO:0043900 69 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
regulation of developmental growth GO:0048638 389 0.014
cell proliferation GO:0008283 116 0.014
Human
macromolecule modification GO:0043412 218 0.014
positive regulation of cell communication GO:0010647 69 0.013
regulation of purine nucleotide metabolic process GO:1900542 37 0.013
neuron recognition GO:0008038 83 0.013
negative regulation of response to stimulus GO:0048585 73 0.013
regulation of anatomical structure size GO:0090066 46 0.013
behavior GO:0007610 527 0.013
regulation of rna splicing GO:0043484 7 0.013
positive regulation of response to stimulus GO:0048584 55 0.013
cell cycle phase transition GO:0044770 19 0.013
positive regulation of multicellular organism growth GO:0040018 352 0.013
negative regulation of gene expression epigenetic GO:0045814 2 0.013
Fly
regulation of chromatin modification GO:1903308 2 0.013
death GO:0016265 547 0.013
regulation of cellular localization GO:0060341 42 0.013
intracellular transport GO:0046907 77 0.012
single organism intracellular transport GO:1902582 70 0.012
male gamete generation GO:0048232 41 0.012
neuroblast fate specification GO:0014018 4 0.012
defense response to other organism GO:0098542 100 0.012
enzyme linked receptor protein signaling pathway GO:0007167 50 0.012
regulation of cellular component biogenesis GO:0044087 26 0.012
covalent chromatin modification GO:0016569 30 0.012
spermatogenesis GO:0007283 41 0.012
phosphorus metabolic process GO:0006793 232 0.012
cell recognition GO:0008037 85 0.012
cellular protein modification process GO:0006464 207 0.012
axonal fasciculation GO:0007413 79 0.012
positive regulation of developmental growth GO:0048639 354 0.012
regulation of transport GO:0051049 91 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.012
cellular response to abiotic stimulus GO:0071214 4 0.012
membrane invagination GO:0010324 98 0.011
response to abiotic stimulus GO:0009628 152 0.011
positive regulation of multicellular organismal process GO:0051240 417 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
dauer larval development GO:0040024 92 0.011
regulation of nucleocytoplasmic transport GO:0046822 3 0.011
muscle organ morphogenesis GO:0048644 4 0.011
apoptotic cell clearance GO:0043277 111 0.011
germ cell development GO:0007281 351 0.011
Fly
regulation of chromatin organization GO:1902275 2 0.011
epithelium development GO:0060429 68 0.011
Fly
mitotic nuclear division GO:0007067 89 0.011
stem cell fate specification GO:0048866 4 0.011
cellular protein localization GO:0034613 75 0.010
cellular ketone metabolic process GO:0042180 14 0.010
response to ketone GO:1901654 1 0.010

pbrm-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
gastrointestinal system cancer DOID:3119 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
nervous system disease DOID:863 0 0.010