Caenorhabditis elegans

132 known processes

tbc-2 (CELE_ZK1248.10)

Protein TBC-2

tbc-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.618
multicellular organism reproduction GO:0032504 819 0.541
organ development GO:0048513 1102 0.497
cell projection organization GO:0030030 231 0.490
aging GO:0007568 812 0.484
developmental process involved in reproduction GO:0003006 1165 0.483
single organism organelle organization GO:1902589 501 0.438
neuron projection development GO:0031175 187 0.431
determination of adult lifespan GO:0008340 812 0.429
development of primary sexual characteristics GO:0045137 840 0.392
single organism reproductive process GO:0044702 1196 0.388
spindle localization GO:0051653 51 0.377
post embryonic development GO:0009791 2152 0.375
sexual reproduction GO:0019953 546 0.374
single organism localization GO:1902578 518 0.368
multicellular organismal reproductive process GO:0048609 815 0.366
oogenesis GO:0048477 229 0.349
cell development GO:0048468 696 0.299
locomotion GO:0040011 1634 0.298
axonogenesis GO:0007409 102 0.297
organelle localization GO:0051640 127 0.272
neuron development GO:0048666 199 0.268
neurogenesis GO:0022008 236 0.267
female gamete generation GO:0007292 254 0.267
gamete generation GO:0007276 461 0.266
reproductive structure development GO:0048608 850 0.259
cell cycle GO:0007049 526 0.258
establishment of localization GO:0051234 1171 0.253
axon development GO:0061564 163 0.253
multicellular organismal aging GO:0010259 812 0.227
establishment of localization in cell GO:0051649 318 0.224
cytoskeleton organization GO:0007010 339 0.222
embryo development ending in birth or egg hatching GO:0009792 2992 0.219
negative regulation of biological process GO:0048519 567 0.206
cell cycle process GO:0022402 482 0.190
sex differentiation GO:0007548 909 0.181
negative regulation of metabolic process GO:0009892 240 0.176
multi organism reproductive process GO:0044703 867 0.176
genitalia development GO:0048806 741 0.175
neuron differentiation GO:0030182 217 0.173
germ cell development GO:0007281 351 0.169
organelle organization GO:0006996 783 0.166
cell part morphogenesis GO:0032990 152 0.162
reproductive system development GO:0061458 850 0.161
protein complex subunit organization GO:0071822 280 0.161
generation of neurons GO:0048699 235 0.156
vesicle mediated transport GO:0016192 852 0.151
microtubule based process GO:0007017 182 0.150
behavior GO:0007610 527 0.149
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.149
macromolecular complex subunit organization GO:0043933 320 0.137
nucleobase containing compound catabolic process GO:0034655 114 0.137
meiotic chromosome segregation GO:0045132 139 0.136
cell projection morphogenesis GO:0048858 148 0.133
cell morphogenesis GO:0000902 163 0.132
regulation of biological quality GO:0065008 741 0.132
Worm
organelle fission GO:0048285 363 0.128
signal transduction GO:0007165 317 0.128
hermaphrodite genitalia development GO:0040035 734 0.126
chromosome segregation GO:0007059 180 0.125
establishment of spindle orientation GO:0051294 34 0.123
response to chemical GO:0042221 356 0.117
macromolecule localization GO:0033036 771 0.117
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.114
endocytosis GO:0006897 819 0.111
cell death GO:0008219 547 0.110
protein complex biogenesis GO:0070271 186 0.104
apoptotic process GO:0006915 478 0.103
tube development GO:0035295 126 0.101
regulation of response to stimulus GO:0048583 243 0.099
phosphorus metabolic process GO:0006793 232 0.099
neuron projection guidance GO:0097485 82 0.098
meiotic cell cycle process GO:1903046 170 0.091
establishment of cell polarity GO:0030010 46 0.089
response to external stimulus GO:0009605 289 0.087
transport GO:0006810 1093 0.086
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.085
establishment or maintenance of cell polarity GO:0007163 63 0.085
nucleic acid metabolic process GO:0090304 299 0.077
growth GO:0040007 562 0.077
negative regulation of gene expression GO:0010629 217 0.076
cellular component morphogenesis GO:0032989 318 0.075
signaling GO:0023052 401 0.074
regulation of developmental process GO:0050793 684 0.071
ribonucleoside triphosphate metabolic process GO:0009199 87 0.071
regulation of multicellular organismal process GO:0051239 726 0.071
heterocycle biosynthetic process GO:0018130 187 0.070
protein localization GO:0008104 205 0.070
regulation of gene expression GO:0010468 366 0.068
neuron projection morphogenesis GO:0048812 114 0.067
oviposition GO:0018991 364 0.067
lipid localization GO:0010876 573 0.067
Worm
programmed cell death GO:0012501 500 0.066
cellular component assembly GO:0022607 293 0.064
single organism cellular localization GO:1902580 72 0.064
gonad development GO:0008406 840 0.063
nervous system development GO:0007399 253 0.062
establishment of mitotic spindle localization GO:0040001 41 0.062
digestive tract development GO:0048565 122 0.062
cellular localization GO:0051641 360 0.062
body morphogenesis GO:0010171 620 0.061
nuclear migration GO:0007097 54 0.059
negative regulation of response to stimulus GO:0048585 73 0.058
regulation of rna biosynthetic process GO:2001141 165 0.058
rna metabolic process GO:0016070 228 0.057
maintenance of location GO:0051235 580 0.056
Worm
positive regulation of cellular metabolic process GO:0031325 178 0.055
lipid storage GO:0019915 565 0.055
Worm
secretion by cell GO:0032940 138 0.055
cellular catabolic process GO:0044248 199 0.054
establishment of mitotic spindle orientation GO:0000132 28 0.054
macromolecule modification GO:0043412 218 0.054
multi organism behavior GO:0051705 389 0.053
purine ribonucleoside metabolic process GO:0046128 92 0.053
purine ribonucleotide catabolic process GO:0009154 75 0.052
negative regulation of macromolecule metabolic process GO:0010605 229 0.051
receptor mediated endocytosis GO:0006898 715 0.050
multi organism reproductive behavior GO:0044705 387 0.050
single organism transport GO:0044765 447 0.049
establishment of spindle localization GO:0051293 51 0.049
negative regulation of developmental process GO:0051093 227 0.048
taxis GO:0042330 128 0.048
response to organic substance GO:0010033 131 0.048
homeostatic process GO:0042592 51 0.047
gene expression GO:0010467 412 0.047
carbohydrate derivative catabolic process GO:1901136 82 0.047
regulation of nitrogen compound metabolic process GO:0051171 222 0.047
developmental growth GO:0048589 412 0.047
organonitrogen compound metabolic process GO:1901564 151 0.046
macromolecule catabolic process GO:0009057 202 0.046
positive regulation of neurogenesis GO:0050769 4 0.046
nucleobase containing compound metabolic process GO:0006139 406 0.045
protein complex assembly GO:0006461 186 0.045
negative regulation of cellular metabolic process GO:0031324 95 0.045
meiotic cell cycle GO:0051321 335 0.045
mitotic cell cycle process GO:1903047 194 0.044
positive regulation of developmental process GO:0051094 408 0.043
digestive system development GO:0055123 122 0.043
meiotic nuclear division GO:0007126 300 0.043
single organism signaling GO:0044700 401 0.042
regulation of localization GO:0032879 194 0.042
macromolecular complex assembly GO:0065003 193 0.042
establishment of organelle localization GO:0051656 123 0.041
regulation of macromolecule metabolic process GO:0060255 421 0.039
cuticle development GO:0042335 100 0.039
regulation of cell communication GO:0010646 176 0.038
cellular component movement GO:0006928 388 0.038
nucleoside metabolic process GO:0009116 99 0.038
carbohydrate derivative metabolic process GO:1901135 141 0.038
cellular protein metabolic process GO:0044267 279 0.038
cell surface receptor signaling pathway GO:0007166 149 0.037
protein modification process GO:0036211 207 0.036
actin cytoskeleton organization GO:0030036 184 0.036
cellular protein modification process GO:0006464 207 0.036
regulation of cell differentiation GO:0045595 81 0.036
single organism catabolic process GO:0044712 129 0.036
negative regulation of signaling GO:0023057 61 0.036
regulation of phosphorus metabolic process GO:0051174 81 0.036
organic substance biosynthetic process GO:1901576 323 0.035
protein phosphorylation GO:0006468 85 0.035
catabolic process GO:0009056 318 0.035
negative regulation of rna biosynthetic process GO:1902679 53 0.035
single organism behavior GO:0044708 83 0.035
death GO:0016265 547 0.034
cellular component biogenesis GO:0044085 297 0.034
chemotaxis GO:0006935 120 0.034
cellular response to stress GO:0033554 162 0.034
nucleobase containing small molecule metabolic process GO:0055086 115 0.033
negative regulation of cellular process GO:0048523 239 0.032
regulation of cellular metabolic process GO:0031323 305 0.032
organic substance catabolic process GO:1901575 294 0.032
cell adhesion GO:0007155 21 0.032
negative regulation of signal transduction GO:0009968 60 0.032
regulation of cell death GO:0010941 65 0.031
regulation of vesicle mediated transport GO:0060627 27 0.031
nucleoside triphosphate catabolic process GO:0009143 72 0.031
cellular biosynthetic process GO:0044249 315 0.031
cytokinesis GO:0000910 80 0.030
protein catabolic process GO:0030163 162 0.029
cellular protein complex assembly GO:0043623 178 0.029
positive regulation of multicellular organismal process GO:0051240 417 0.029
reproductive behavior GO:0019098 387 0.029
cellular macromolecule localization GO:0070727 75 0.028
endosomal transport GO:0016197 26 0.028
anatomical structure formation involved in morphogenesis GO:0048646 250 0.027
regulation of cellular component organization GO:0051128 248 0.027
developmental growth involved in morphogenesis GO:0060560 37 0.026
muscle cell differentiation GO:0042692 171 0.026
cell recognition GO:0008037 85 0.026
positive regulation of cell projection organization GO:0031346 4 0.026
negative regulation of cell communication GO:0010648 61 0.026
organelle assembly GO:0070925 214 0.026
phosphate containing compound metabolic process GO:0006796 232 0.025
regulation of primary metabolic process GO:0080090 292 0.025
chromosome organization GO:0051276 104 0.025
ribonucleoside triphosphate catabolic process GO:0009203 72 0.025
ras protein signal transduction GO:0007265 31 0.025
multi multicellular organism process GO:0044706 390 0.025
nucleoside phosphate metabolic process GO:0006753 108 0.025
positive regulation of multicellular organism growth GO:0040018 352 0.024
negative regulation of post embryonic development GO:0048581 208 0.023
nucleic acid templated transcription GO:0097659 169 0.023
regulation of catalytic activity GO:0050790 78 0.023
purine ribonucleoside catabolic process GO:0046130 75 0.023
macromolecule biosynthetic process GO:0009059 250 0.023
positive regulation of growth GO:0045927 369 0.023
positive regulation of neuron differentiation GO:0045666 4 0.023
response to wounding GO:0009611 4 0.023
organophosphate catabolic process GO:0046434 81 0.022
ribonucleotide catabolic process GO:0009261 75 0.022
regulation of locomotion GO:0040012 161 0.022
cellular macromolecular complex assembly GO:0034622 184 0.022
dna metabolic process GO:0006259 74 0.022
system process GO:0003008 136 0.022
rho protein signal transduction GO:0007266 2 0.022
striated muscle cell development GO:0055002 157 0.022
vulval development GO:0040025 333 0.022
sensory organ morphogenesis GO:0090596 2 0.022
adult behavior GO:0030534 3 0.021
regulation of signaling GO:0023051 172 0.021
protein oligomerization GO:0051259 4 0.021
negative regulation of cellular component organization GO:0051129 33 0.021
neuron recognition GO:0008038 83 0.021
regulation of nucleoside metabolic process GO:0009118 37 0.021
cellular protein localization GO:0034613 75 0.021
phagocytosis GO:0006909 115 0.021
actin filament based process GO:0030029 191 0.021
negative regulation of transcription dna templated GO:0045892 53 0.020
regulation of multicellular organism growth GO:0040014 373 0.020
nucleoside phosphate catabolic process GO:1901292 77 0.020
striated muscle cell differentiation GO:0051146 158 0.020
posttranscriptional gene silencing GO:0016441 143 0.020
intracellular transport GO:0046907 77 0.020
cell division GO:0051301 262 0.020
regulation of cell development GO:0060284 49 0.020
response to oxygen containing compound GO:1901700 44 0.020
defense response GO:0006952 296 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.019
positive regulation of cellular process GO:0048522 332 0.019
cellular response to chemical stimulus GO:0070887 129 0.019
muscle structure development GO:0061061 191 0.019
protein transport GO:0015031 45 0.019
cellular response to organic substance GO:0071310 119 0.019
positive regulation of transferase activity GO:0051347 21 0.019
regulation of cell migration GO:0030334 55 0.019
regulation of developmental growth GO:0048638 389 0.019
purine containing compound catabolic process GO:0072523 75 0.019
regulation of gene expression epigenetic GO:0040029 163 0.019
protein metabolic process GO:0019538 422 0.018
male gamete generation GO:0048232 41 0.018
regulation of signal transduction GO:0009966 135 0.018
positive regulation of jnk cascade GO:0046330 3 0.018
phosphorylation GO:0016310 116 0.018
positive regulation of developmental growth GO:0048639 354 0.018
defense response to gram negative bacterium GO:0050829 64 0.018
post embryonic organ development GO:0048569 336 0.018
regulation of growth GO:0040008 409 0.018
spindle organization GO:0007051 92 0.018
organic substance transport GO:0071702 113 0.017
purine nucleotide catabolic process GO:0006195 75 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.017
biosynthetic process GO:0009058 323 0.017
positive regulation of stress activated mapk cascade GO:0032874 3 0.017
purine nucleoside metabolic process GO:0042278 92 0.017
regulation of molecular function GO:0065009 89 0.017
actomyosin structure organization GO:0031032 154 0.017
dauer larval development GO:0040024 92 0.017
intracellular signal transduction GO:0035556 96 0.017
positive regulation of metabolic process GO:0009893 187 0.017
asymmetric protein localization GO:0008105 35 0.017
lipid metabolic process GO:0006629 77 0.016
response to external biotic stimulus GO:0043207 101 0.016
regulation of multicellular organismal development GO:2000026 317 0.016
biological adhesion GO:0022610 21 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.016
regulation of metabolic process GO:0019222 478 0.016
rna interference GO:0016246 137 0.016
positive regulation of cellular catabolic process GO:0031331 35 0.015
organic cyclic compound biosynthetic process GO:1901362 195 0.015
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.015
regulation of transcription dna templated GO:0006355 164 0.015
oocyte differentiation GO:0009994 45 0.015
tissue morphogenesis GO:0048729 65 0.015
germ line stem cell division GO:0042078 9 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
aromatic compound biosynthetic process GO:0019438 192 0.014
cellular response to dna damage stimulus GO:0006974 41 0.014
intracellular receptor signaling pathway GO:0030522 2 0.014
regulation of programmed cell death GO:0043067 50 0.014
spermatogenesis GO:0007283 41 0.014
organophosphate metabolic process GO:0019637 125 0.014
regulation of nervous system development GO:0051960 41 0.014
glycosyl compound metabolic process GO:1901657 100 0.014
cell matrix adhesion GO:0007160 1 0.014
embryonic morphogenesis GO:0048598 152 0.014
gene silencing GO:0016458 143 0.014
microtubule polymerization or depolymerization GO:0031109 22 0.014
posttranscriptional regulation of gene expression GO:0010608 166 0.014
cell type specific apoptotic process GO:0097285 4 0.014
proteolysis GO:0006508 61 0.014
cell migration GO:0016477 306 0.013
axon guidance GO:0007411 82 0.013
response to organonitrogen compound GO:0010243 15 0.013
regulation of neurogenesis GO:0050767 40 0.013
regulation of cellular component movement GO:0051270 62 0.013
positive regulation of neuron projection development GO:0010976 4 0.013
regulation of phosphate metabolic process GO:0019220 81 0.013
purine nucleotide metabolic process GO:0006163 95 0.013
dendrite development GO:0016358 42 0.013
adult locomotory behavior GO:0008344 1 0.012
negative regulation of multicellular organismal process GO:0051241 236 0.012
secretion GO:0046903 147 0.012
defense response to bacterium GO:0042742 86 0.012
multicellular organism growth GO:0035264 385 0.012
nucleotide metabolic process GO:0009117 108 0.012
regulation of behavior GO:0050795 97 0.012
positive regulation of catalytic activity GO:0043085 59 0.012
establishment of nucleus localization GO:0040023 55 0.012
nucleobase containing compound biosynthetic process GO:0034654 184 0.012
gene silencing by rna GO:0031047 143 0.012
axonal fasciculation GO:0007413 79 0.012
regulation of post embryonic development GO:0048580 260 0.012
head development GO:0060322 1 0.012
regeneration GO:0031099 4 0.012
neuromuscular junction development GO:0007528 2 0.012
cellular macromolecule biosynthetic process GO:0034645 247 0.012
glycosyl compound catabolic process GO:1901658 79 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
cellular nitrogen compound catabolic process GO:0044270 119 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.012
cell substrate adhesion GO:0031589 1 0.011
purine nucleoside triphosphate catabolic process GO:0009146 72 0.011
heterocycle catabolic process GO:0046700 119 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
immune response GO:0006955 192 0.011
notch signaling pathway GO:0007219 22 0.011
tissue development GO:0009888 112 0.011
purine ribonucleotide metabolic process GO:0009150 95 0.011
response to acid chemical GO:0001101 4 0.011
ion transport GO:0006811 113 0.011
mitotic spindle organization GO:0007052 81 0.011
localization of cell GO:0051674 313 0.011
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.011
ovulation GO:0030728 33 0.011
regulation of organelle organization GO:0033043 164 0.011
cellular response to nitrogen compound GO:1901699 24 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
response to bacterium GO:0009617 86 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.011
cellular component assembly involved in morphogenesis GO:0010927 183 0.010
establishment of protein localization to mitochondrial membrane GO:0090151 2 0.010
neurological system process GO:0050877 53 0.010
positive regulation of response to stimulus GO:0048584 55 0.010
ribose phosphate metabolic process GO:0019693 99 0.010
regulation of cytoskeleton organization GO:0051493 41 0.010
ribonucleotide metabolic process GO:0009259 99 0.010
regulation of transport GO:0051049 91 0.010
regulation of biosynthetic process GO:0009889 189 0.010
regulation of ras protein signal transduction GO:0046578 41 0.010

tbc-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036