Caenorhabditis elegans

51 known processes

msh-2 (CELE_H26D21.2)

Protein MSH-2

msh-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.513
embryo development ending in birth or egg hatching GO:0009792 2992 0.454
post embryonic development GO:0009791 2152 0.310
single organism reproductive process GO:0044702 1196 0.279
Yeast
phosphorus metabolic process GO:0006793 232 0.266
Human Yeast
cell cycle GO:0007049 526 0.251
Yeast
multicellular organism reproduction GO:0032504 819 0.218
nucleobase containing compound metabolic process GO:0006139 406 0.207
organelle fission GO:0048285 363 0.180
Yeast
negative regulation of biological process GO:0048519 567 0.177
Human Yeast
multicellular organismal reproductive process GO:0048609 815 0.166
reproductive structure development GO:0048608 850 0.153
locomotion GO:0040011 1634 0.144
regulation of multicellular organism growth GO:0040014 373 0.143
growth GO:0040007 562 0.143
regulation of multicellular organismal process GO:0051239 726 0.137
developmental process involved in reproduction GO:0003006 1165 0.132
Yeast
nucleobase containing small molecule metabolic process GO:0055086 115 0.131
Human Yeast
transport GO:0006810 1093 0.130
chromosome segregation GO:0007059 180 0.126
regulation of metabolic process GO:0019222 478 0.125
Human Yeast
regulation of growth GO:0040008 409 0.120
genitalia development GO:0048806 741 0.118
positive regulation of developmental growth GO:0048639 354 0.109
ribonucleotide metabolic process GO:0009259 99 0.107
Human Yeast
vesicle mediated transport GO:0016192 852 0.107
cellular biosynthetic process GO:0044249 315 0.104
Yeast
macromolecule localization GO:0033036 771 0.101
regulation of gene expression GO:0010468 366 0.100
Yeast
hermaphrodite genitalia development GO:0040035 734 0.100
gamete generation GO:0007276 461 0.098
body morphogenesis GO:0010171 620 0.093
sex differentiation GO:0007548 909 0.090
regulation of developmental process GO:0050793 684 0.089
receptor mediated endocytosis GO:0006898 715 0.087
cell cycle process GO:0022402 482 0.086
Yeast
sexual reproduction GO:0019953 546 0.081
endocytosis GO:0006897 819 0.081
purine nucleoside triphosphate catabolic process GO:0009146 72 0.079
Human Yeast
organ development GO:0048513 1102 0.078
positive regulation of multicellular organism growth GO:0040018 352 0.078
regulation of biological quality GO:0065008 741 0.078
single organism localization GO:1902578 518 0.077
multicellular organism growth GO:0035264 385 0.077
ribonucleoside triphosphate metabolic process GO:0009199 87 0.076
Human Yeast
establishment of localization GO:0051234 1171 0.074
meiotic chromosome segregation GO:0045132 139 0.072
cellular macromolecule biosynthetic process GO:0034645 247 0.072
Yeast
developmental growth GO:0048589 412 0.071
organonitrogen compound metabolic process GO:1901564 151 0.071
Human Yeast
glycosyl compound metabolic process GO:1901657 100 0.070
Human Yeast
regulation of cellular metabolic process GO:0031323 305 0.070
Human Yeast
positive regulation of growth GO:0045927 369 0.069
ribonucleoside metabolic process GO:0009119 98 0.069
Human Yeast
organic substance biosynthetic process GO:1901576 323 0.069
Yeast
regulation of developmental growth GO:0048638 389 0.067
cellular catabolic process GO:0044248 199 0.067
Human Yeast
cell division GO:0051301 262 0.067
phosphate containing compound metabolic process GO:0006796 232 0.065
Human Yeast
nucleoside triphosphate metabolic process GO:0009141 87 0.064
Human Yeast
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.063
positive regulation of developmental process GO:0051094 408 0.063
nucleotide metabolic process GO:0009117 108 0.062
Human Yeast
multi organism reproductive process GO:0044703 867 0.060
reproductive system development GO:0061458 850 0.060
organic substance catabolic process GO:1901575 294 0.060
Human Yeast
regulation of cell cycle GO:0051726 194 0.059
female meiotic division GO:0007143 17 0.059
maintenance of location GO:0051235 580 0.058
protein localization GO:0008104 205 0.058
sister chromatid segregation GO:0000819 46 0.058
biosynthetic process GO:0009058 323 0.058
Yeast
membrane organization GO:0061024 135 0.057
development of primary sexual characteristics GO:0045137 840 0.057
lipid storage GO:0019915 565 0.057
meiotic cell cycle GO:0051321 335 0.056
Yeast
lipid localization GO:0010876 573 0.056
carbohydrate derivative catabolic process GO:1901136 82 0.055
Human Yeast
posttranscriptional regulation of gene expression GO:0010608 166 0.053
nucleoside metabolic process GO:0009116 99 0.052
Human Yeast
nucleic acid metabolic process GO:0090304 299 0.052
ribose phosphate metabolic process GO:0019693 99 0.052
Human Yeast
multicellular organismal aging GO:0010259 812 0.051
positive regulation of multicellular organismal process GO:0051240 417 0.049
catabolic process GO:0009056 318 0.049
Human Yeast
meiotic cell cycle process GO:1903046 170 0.049
Yeast
gene silencing GO:0016458 143 0.048
Yeast
chromosome organization GO:0051276 104 0.048
single organism organelle organization GO:1902589 501 0.048
regulation of localization GO:0032879 194 0.048
cellular protein metabolic process GO:0044267 279 0.048
purine nucleoside metabolic process GO:0042278 92 0.047
Human Yeast
organelle assembly GO:0070925 214 0.047
signal transduction GO:0007165 317 0.047
positive regulation of cellular process GO:0048522 332 0.045
purine nucleotide catabolic process GO:0006195 75 0.044
Human Yeast
cell development GO:0048468 696 0.044
cellular component assembly involved in morphogenesis GO:0010927 183 0.044
mitotic nuclear division GO:0007067 89 0.044
rna interference GO:0016246 137 0.043
dna duplex unwinding GO:0032508 3 0.043
aging GO:0007568 812 0.043
multicellular organismal reproductive behavior GO:0033057 384 0.042
negative regulation of cellular process GO:0048523 239 0.042
Human Yeast
purine ribonucleotide metabolic process GO:0009150 95 0.041
Human Yeast
purine nucleotide metabolic process GO:0006163 95 0.041
Human Yeast
single organism transport GO:0044765 447 0.040
oviposition GO:0018991 364 0.038
carbohydrate derivative metabolic process GO:1901135 141 0.038
Human Yeast
small molecule metabolic process GO:0044281 186 0.038
Human Yeast
ribonucleoside monophosphate metabolic process GO:0009161 45 0.038
Human Yeast
regulation of primary metabolic process GO:0080090 292 0.036
Human Yeast
cellular localization GO:0051641 360 0.036
multi organism reproductive behavior GO:0044705 387 0.036
purine containing compound catabolic process GO:0072523 75 0.035
Human Yeast
gene expression GO:0010467 412 0.035
Yeast
purine containing compound metabolic process GO:0072521 95 0.035
Human Yeast
single organism signaling GO:0044700 401 0.034
microtubule based movement GO:0007018 33 0.034
chromosome organization involved in meiosis GO:0070192 25 0.034
rna metabolic process GO:0016070 228 0.033
Yeast
germ cell development GO:0007281 351 0.033
negative regulation of metabolic process GO:0009892 240 0.033
Human Yeast
cell fate commitment GO:0045165 139 0.033
Yeast
multi multicellular organism process GO:0044706 390 0.033
regulation of macromolecule biosynthetic process GO:0010556 189 0.033
Yeast
purine ribonucleotide catabolic process GO:0009154 75 0.033
Human Yeast
oogenesis GO:0048477 229 0.032
purine ribonucleoside catabolic process GO:0046130 75 0.031
Human Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.031
Human Yeast
nucleoside triphosphate catabolic process GO:0009143 72 0.031
Human Yeast
maintenance of protein location in cell GO:0032507 12 0.031
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.030
regulation of cellular biosynthetic process GO:0031326 189 0.030
Yeast
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.030
Human Yeast
macromolecule modification GO:0043412 218 0.030
glycosyl compound catabolic process GO:1901658 79 0.030
Human Yeast
behavior GO:0007610 527 0.030
regulation of macromolecule metabolic process GO:0060255 421 0.030
Human Yeast
meiotic nuclear division GO:0007126 300 0.029
Yeast
establishment of organelle localization GO:0051656 123 0.029
multi organism behavior GO:0051705 389 0.029
posttranscriptional gene silencing GO:0016441 143 0.028
ribonucleoside catabolic process GO:0042454 77 0.028
Human Yeast
regulation of catabolic process GO:0009894 57 0.027
macromolecule biosynthetic process GO:0009059 250 0.027
Yeast
protein complex subunit organization GO:0071822 280 0.027
organophosphate metabolic process GO:0019637 125 0.027
Human Yeast
regulation of catalytic activity GO:0050790 78 0.027
Human
cell death GO:0008219 547 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.026
Human Yeast
determination of adult lifespan GO:0008340 812 0.026
positive regulation of catalytic activity GO:0043085 59 0.026
Human
purine ribonucleoside metabolic process GO:0046128 92 0.025
Human Yeast
collagen and cuticulin based cuticle development GO:0040002 99 0.025
cell cell signaling GO:0007267 118 0.025
polar body extrusion after meiotic divisions GO:0040038 14 0.025
positive regulation of epithelial cell proliferation GO:0050679 1 0.025
membrane invagination GO:0010324 98 0.025
purine nucleoside monophosphate metabolic process GO:0009126 43 0.025
Human Yeast
regulation of multicellular organismal development GO:2000026 317 0.025
regulation of response to stimulus GO:0048583 243 0.025
protein metabolic process GO:0019538 422 0.025
protein complex assembly GO:0006461 186 0.025
organelle organization GO:0006996 783 0.024
female gamete generation GO:0007292 254 0.024
cellular component biogenesis GO:0044085 297 0.024
microtubule based process GO:0007017 182 0.024
anatomical structure formation involved in morphogenesis GO:0048646 250 0.024
response to bacterium GO:0009617 86 0.023
nucleoside monophosphate metabolic process GO:0009123 46 0.023
Human Yeast
tube development GO:0035295 126 0.023
cellular protein localization GO:0034613 75 0.023
purine nucleoside triphosphate metabolic process GO:0009144 87 0.023
Human Yeast
cuticle development GO:0042335 100 0.022
purine nucleoside catabolic process GO:0006152 75 0.022
Human Yeast
ribonucleotide catabolic process GO:0009261 75 0.021
Human Yeast
single organism biosynthetic process GO:0044711 91 0.021
regulation of organelle organization GO:0033043 164 0.021
nucleobase containing compound biosynthetic process GO:0034654 184 0.021
Yeast
organelle localization GO:0051640 127 0.020
macromolecular complex subunit organization GO:0043933 320 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.020
cellular component assembly GO:0022607 293 0.020
gonad development GO:0008406 840 0.020
actomyosin structure organization GO:0031032 154 0.020
protein complex biogenesis GO:0070271 186 0.020
cell proliferation GO:0008283 116 0.020
striated muscle cell differentiation GO:0051146 158 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.019
Human Yeast
nucleobase containing compound catabolic process GO:0034655 114 0.019
Human Yeast
establishment of localization in cell GO:0051649 318 0.018
molting cycle GO:0042303 281 0.018
organophosphate catabolic process GO:0046434 81 0.018
Human Yeast
neuron differentiation GO:0030182 217 0.018
cellular component morphogenesis GO:0032989 318 0.018
attachment of mitotic spindle microtubules to kinetochore GO:0051315 6 0.018
aromatic compound biosynthetic process GO:0019438 192 0.018
Yeast
cellular response to stress GO:0033554 162 0.018
nucleoside phosphate metabolic process GO:0006753 108 0.018
Human Yeast
macromolecular complex assembly GO:0065003 193 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
protein modification process GO:0036211 207 0.017
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.017
reproductive behavior GO:0019098 387 0.017
cellular macromolecular complex assembly GO:0034622 184 0.017
regulation of nematode larval development GO:0061062 260 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
rna localization GO:0006403 3 0.016
response to chemical GO:0042221 356 0.016
cellular macromolecule localization GO:0070727 75 0.016
male gamete generation GO:0048232 41 0.016
dna metabolic process GO:0006259 74 0.016
regulation of intracellular signal transduction GO:1902531 77 0.016
rna biosynthetic process GO:0032774 169 0.016
Yeast
establishment of spindle localization GO:0051293 51 0.016
gene silencing by rna GO:0031047 143 0.016
dna recombination GO:0006310 19 0.016
Human Yeast
regulation of cell communication GO:0010646 176 0.016
cellular component movement GO:0006928 388 0.016
regulation of phosphorus metabolic process GO:0051174 81 0.016
dna geometric change GO:0032392 3 0.016
intracellular transport GO:0046907 77 0.015
regulation of protein metabolic process GO:0051246 81 0.015
kinetochore organization GO:0051383 7 0.015
cellular nitrogen compound catabolic process GO:0044270 119 0.015
Human Yeast
spindle organization GO:0007051 92 0.015
macromolecule catabolic process GO:0009057 202 0.015
Yeast
spermatogenesis GO:0007283 41 0.015
defense response to bacterium GO:0042742 86 0.015
regulation of nucleic acid templated transcription GO:1903506 165 0.015
Yeast
negative regulation of gene expression GO:0010629 217 0.015
Yeast
positive regulation of catabolic process GO:0009896 38 0.015
atp catabolic process GO:0006200 27 0.015
Human Yeast
regulation of biosynthetic process GO:0009889 189 0.015
Yeast
mitotic cell cycle process GO:1903047 194 0.015
single organism intracellular transport GO:1902582 70 0.015
defense response GO:0006952 296 0.015
dna conformation change GO:0071103 11 0.015
regulation of gene expression epigenetic GO:0040029 163 0.015
Yeast
cellular response to chemical stimulus GO:0070887 129 0.014
organic substance transport GO:0071702 113 0.014
myosin filament assembly GO:0031034 138 0.014
myosin filament organization GO:0031033 138 0.014
muscle structure development GO:0061061 191 0.014
single organism membrane organization GO:0044802 35 0.014
spindle localization GO:0051653 51 0.014
regulation of meiotic cell cycle GO:0051445 136 0.014
regulation of cell cycle process GO:0010564 145 0.014
cell projection organization GO:0030030 231 0.014
regulation of nitrogen compound metabolic process GO:0051171 222 0.014
Human Yeast
oocyte differentiation GO:0009994 45 0.014
ribonucleoside triphosphate catabolic process GO:0009203 72 0.014
Human Yeast
phagocytosis GO:0006909 115 0.014
protein oligomerization GO:0051259 4 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
mitotic sister chromatid segregation GO:0000070 38 0.013
neuron projection development GO:0031175 187 0.013
negative regulation of developmental process GO:0051093 227 0.013
cellular response to abiotic stimulus GO:0071214 4 0.013
negative regulation of multicellular organismal process GO:0051241 236 0.013
regulation of signal transduction GO:0009966 135 0.013
response to acid chemical GO:0001101 4 0.013
regulation of cell proliferation GO:0042127 105 0.013
post embryonic organ development GO:0048569 336 0.013
phagocytosis engulfment GO:0006911 98 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.012
muscle cell differentiation GO:0042692 171 0.012
heterocycle biosynthetic process GO:0018130 187 0.012
Yeast
g1 s transition of mitotic cell cycle GO:0000082 2 0.012
regulation of translation GO:0006417 19 0.012
nucleoside phosphate catabolic process GO:1901292 77 0.012
Human Yeast
regulation of cellular catabolic process GO:0031329 51 0.012
cellular protein modification process GO:0006464 207 0.012
negative regulation of macromolecule metabolic process GO:0010605 229 0.012
Human Yeast
oocyte development GO:0048599 44 0.012
regulation of phosphate metabolic process GO:0019220 81 0.012
protein catabolic process GO:0030163 162 0.012
single fertilization GO:0007338 61 0.012
male sex differentiation GO:0046661 86 0.012
regulation of protein localization GO:0032880 50 0.012
intracellular signal transduction GO:0035556 96 0.012
signaling GO:0023052 401 0.012
positive regulation of cellular protein catabolic process GO:1903364 3 0.012
nucleoside catabolic process GO:0009164 78 0.011
Human Yeast
meiosis ii GO:0007135 16 0.011
regulation of mitotic cell cycle GO:0007346 76 0.011
cytoskeleton organization GO:0007010 339 0.011
digestive system development GO:0055123 122 0.011
regulation of cellular component organization GO:0051128 248 0.011
vulval development GO:0040025 333 0.011
cellular response to organic substance GO:0071310 119 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
ubiquitin dependent protein catabolic process GO:0006511 32 0.011
engulfment of apoptotic cell GO:0043652 94 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
cell cycle g1 s phase transition GO:0044843 2 0.011
actin cytoskeleton organization GO:0030036 184 0.011
cell surface receptor signaling pathway GO:0007166 149 0.011
single organism cellular localization GO:1902580 72 0.010
regulation of nuclear division GO:0051783 115 0.010
regulation of transcription dna templated GO:0006355 164 0.010
Yeast
localization of cell GO:0051674 313 0.010
meiosis i GO:0007127 19 0.010
Yeast
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.010
protein localization to organelle GO:0033365 37 0.010
embryonic morphogenesis GO:0048598 152 0.010
response to wounding GO:0009611 4 0.010

msh-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
disease of anatomical entity DOID:7 0 0.014
organ system cancer DOID:0050686 0 0.013
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013