Caenorhabditis elegans

94 known processes

egl-43 (CELE_R53.3)

Protein EGL-43

egl-43 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.336
Zebrafish Mouse
single organism reproductive process GO:0044702 1196 0.299
post embryonic development GO:0009791 2152 0.293
embryo development GO:0009790 3052 0.283
Zebrafish Mouse
multicellular organism reproduction GO:0032504 819 0.269
multicellular organismal reproductive process GO:0048609 815 0.247
organ development GO:0048513 1102 0.206
multi organism reproductive process GO:0044703 867 0.185
multi organism reproductive behavior GO:0044705 387 0.168
post embryonic organ development GO:0048569 336 0.160
locomotion GO:0040011 1634 0.156
response to external stimulus GO:0009605 289 0.154
Mouse
developmental process involved in reproduction GO:0003006 1165 0.152
multicellular organismal reproductive behavior GO:0033057 384 0.148
death GO:0016265 547 0.141
vulval development GO:0040025 333 0.135
endocytosis GO:0006897 819 0.125
muscle tissue development GO:0060537 1 0.123
sexual reproduction GO:0019953 546 0.123
gonad development GO:0008406 840 0.121
oviposition GO:0018991 364 0.117
reproductive behavior GO:0019098 387 0.114
regulation of metabolic process GO:0019222 478 0.112
Mouse Fly
cell death GO:0008219 547 0.112
cell development GO:0048468 696 0.111
reproductive system development GO:0061458 850 0.111
negative regulation of biological process GO:0048519 567 0.104
cellular biosynthetic process GO:0044249 315 0.098
Mouse Fly
regulation of vulval development GO:0040028 248 0.097
single organism signaling GO:0044700 401 0.093
Mouse
multi organism behavior GO:0051705 389 0.093
hermaphrodite genitalia development GO:0040035 734 0.092
organic cyclic compound biosynthetic process GO:1901362 195 0.091
Mouse Fly
development of primary sexual characteristics GO:0045137 840 0.091
reproductive structure development GO:0048608 850 0.090
multi multicellular organism process GO:0044706 390 0.087
aromatic compound biosynthetic process GO:0019438 192 0.086
Mouse Fly
head development GO:0060322 1 0.085
Mouse
transport GO:0006810 1093 0.085
sex differentiation GO:0007548 909 0.085
response to chemical GO:0042221 356 0.082
Mouse
macromolecule localization GO:0033036 771 0.078
cellular nitrogen compound biosynthetic process GO:0044271 192 0.077
Mouse Fly
genitalia development GO:0048806 741 0.076
vesicle mediated transport GO:0016192 852 0.076
determination of adult lifespan GO:0008340 812 0.076
programmed cell death GO:0012501 500 0.074
negative regulation of metabolic process GO:0009892 240 0.072
Mouse
behavior GO:0007610 527 0.072
neuron differentiation GO:0030182 217 0.071
multicellular organismal aging GO:0010259 812 0.071
regulation of post embryonic development GO:0048580 260 0.071
gamete generation GO:0007276 461 0.070
organic substance biosynthetic process GO:1901576 323 0.069
Mouse Fly
regulation of biological quality GO:0065008 741 0.068
Mouse
transcription from rna polymerase ii promoter GO:0006366 149 0.068
Mouse
maintenance of location GO:0051235 580 0.066
cellular macromolecule biosynthetic process GO:0034645 247 0.066
Mouse Fly
lipid storage GO:0019915 565 0.065
aging GO:0007568 812 0.064
regulation of cellular metabolic process GO:0031323 305 0.064
Mouse Fly
regulation of multicellular organismal process GO:0051239 726 0.063
nucleic acid templated transcription GO:0097659 169 0.062
Mouse Fly
lipid localization GO:0010876 573 0.061
nucleobase containing compound metabolic process GO:0006139 406 0.060
Mouse Fly
regulation of gene expression GO:0010468 366 0.060
Mouse Fly
regulation of rna biosynthetic process GO:2001141 165 0.059
Mouse Fly
regulation of response to stimulus GO:0048583 243 0.059
Mouse
nucleic acid metabolic process GO:0090304 299 0.058
Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.057
Mouse Fly
establishment of localization GO:0051234 1171 0.057
apoptotic process GO:0006915 478 0.055
response to wounding GO:0009611 4 0.053
signal transduction GO:0007165 317 0.052
Mouse
female gamete generation GO:0007292 254 0.052
cell projection organization GO:0030030 231 0.052
Fly
growth GO:0040007 562 0.051
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.051
regulation of multicellular organismal development GO:2000026 317 0.051
neuron development GO:0048666 199 0.050
Fly
regulation of nematode larval development GO:0061062 260 0.050
negative regulation of gene expression GO:0010629 217 0.049
Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.049
gene expression GO:0010467 412 0.048
Mouse Fly
signaling GO:0023052 401 0.048
Mouse
response to external biotic stimulus GO:0043207 101 0.046
Mouse
cell morphogenesis GO:0000902 163 0.046
Fly
regulation of nitrogen compound metabolic process GO:0051171 222 0.046
Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.045
Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.043
macromolecule biosynthetic process GO:0009059 250 0.043
Mouse Fly
receptor mediated endocytosis GO:0006898 715 0.043
regulation of macromolecule biosynthetic process GO:0010556 189 0.043
Mouse Fly
regulation of signaling GO:0023051 172 0.043
Mouse
nervous system development GO:0007399 253 0.043
germ cell development GO:0007281 351 0.042
positive regulation of developmental process GO:0051094 408 0.041
regulation of cellular biosynthetic process GO:0031326 189 0.040
Mouse Fly
molting cycle GO:0042303 281 0.040
single organism transport GO:0044765 447 0.040
regulation of rna metabolic process GO:0051252 173 0.040
Mouse Fly
regulation of developmental process GO:0050793 684 0.040
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.040
Mouse Fly
generation of neurons GO:0048699 235 0.039
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.039
cell cycle process GO:0022402 482 0.039
heterocycle biosynthetic process GO:0018130 187 0.039
Mouse Fly
negative regulation of cellular metabolic process GO:0031324 95 0.038
Mouse
cellular component morphogenesis GO:0032989 318 0.038
Fly
regulation of biosynthetic process GO:0009889 189 0.038
Mouse Fly
oogenesis GO:0048477 229 0.038
rna metabolic process GO:0016070 228 0.038
Mouse Fly
positive regulation of transcription dna templated GO:0045893 102 0.037
Mouse
biosynthetic process GO:0009058 323 0.037
Mouse Fly
response to other organism GO:0051707 101 0.036
Mouse
organic substance catabolic process GO:1901575 294 0.036
positive regulation of rna biosynthetic process GO:1902680 102 0.036
Mouse
negative regulation of macromolecule metabolic process GO:0010605 229 0.036
Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.035
Mouse Fly
organelle organization GO:0006996 783 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.034
Mouse
regulation of multicellular organism growth GO:0040014 373 0.034
transcription dna templated GO:0006351 168 0.033
Mouse Fly
cell migration GO:0016477 306 0.033
regulation of growth GO:0040008 409 0.033
neuron projection development GO:0031175 187 0.032
Fly
regulation of transcription dna templated GO:0006355 164 0.032
Mouse Fly
positive regulation of multicellular organism growth GO:0040018 352 0.032
developmental growth GO:0048589 412 0.031
response to abiotic stimulus GO:0009628 152 0.031
regulation of nucleic acid templated transcription GO:1903506 165 0.030
Mouse Fly
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.030
Mouse
regulation of cell communication GO:0010646 176 0.030
Mouse
positive regulation of rna metabolic process GO:0051254 103 0.030
Mouse
small molecule metabolic process GO:0044281 186 0.029
regulation of primary metabolic process GO:0080090 292 0.029
Mouse Fly
negative regulation of post embryonic development GO:0048581 208 0.029
multicellular organism growth GO:0035264 385 0.028
cell proliferation GO:0008283 116 0.028
Mouse Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.028
Mouse
positive regulation of growth GO:0045927 369 0.028
cell type specific apoptotic process GO:0097285 4 0.028
mating behavior GO:0007617 32 0.027
mating GO:0007618 34 0.027
negative regulation of cellular process GO:0048523 239 0.027
Mouse Fly
negative regulation of biosynthetic process GO:0009890 65 0.027
Mouse
negative regulation of transcription dna templated GO:0045892 53 0.027
Mouse
regulation of cell differentiation GO:0045595 81 0.026
positive regulation of macromolecule metabolic process GO:0010604 149 0.026
Mouse
cell morphogenesis involved in differentiation GO:0000904 112 0.026
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.026
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.026
single organism localization GO:1902578 518 0.025
cellular localization GO:0051641 360 0.025
cellular component movement GO:0006928 388 0.025
response to biotic stimulus GO:0009607 101 0.025
Mouse
body morphogenesis GO:0010171 620 0.025
regulation of cell proliferation GO:0042127 105 0.025
Mouse Fly
negative regulation of nematode larval development GO:0061064 208 0.025
negative regulation of rna biosynthetic process GO:1902679 53 0.025
Mouse
positive regulation of developmental growth GO:0048639 354 0.025
system process GO:0003008 136 0.025
cellular component biogenesis GO:0044085 297 0.024
neurogenesis GO:0022008 236 0.024
response to osmotic stress GO:0006970 29 0.024
regulation of developmental growth GO:0048638 389 0.024
regulation of signal transduction GO:0009966 135 0.023
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.023
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.023
Mouse Fly
positive regulation of cellular process GO:0048522 332 0.023
Mouse
regulation of multi organism process GO:0043900 69 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.022
Mouse
organonitrogen compound metabolic process GO:1901564 151 0.022
protein localization GO:0008104 205 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
Mouse
regulation of cell cycle process GO:0010564 145 0.021
positive regulation of biosynthetic process GO:0009891 109 0.021
Mouse
cell cycle GO:0007049 526 0.020
cell division GO:0051301 262 0.020
tube development GO:0035295 126 0.020
ras protein signal transduction GO:0007265 31 0.020
digestive tract development GO:0048565 122 0.020
cell motility GO:0048870 313 0.020
negative regulation of response to stimulus GO:0048585 73 0.019
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.019
Fly
dna metabolic process GO:0006259 74 0.019
protein metabolic process GO:0019538 422 0.019
embryonic morphogenesis GO:0048598 152 0.019
Zebrafish Mouse
small gtpase mediated signal transduction GO:0007264 32 0.019
secretion GO:0046903 147 0.019
regulation of reproductive process GO:2000241 66 0.019
regulation of cell cycle GO:0051726 194 0.018
cellular component assembly GO:0022607 293 0.018
digestive tract morphogenesis GO:0048546 76 0.018
sensory organ morphogenesis GO:0090596 2 0.018
digestive system development GO:0055123 122 0.018
intracellular signal transduction GO:0035556 96 0.018
negative regulation of cellular biosynthetic process GO:0031327 65 0.018
Mouse
defense response GO:0006952 296 0.017
Mouse
dendrite development GO:0016358 42 0.017
Fly
cellular component assembly involved in morphogenesis GO:0010927 183 0.017
neuron recognition GO:0008038 83 0.017
positive regulation of cellular metabolic process GO:0031325 178 0.017
Mouse
macromolecule modification GO:0043412 218 0.017
single organism biosynthetic process GO:0044711 91 0.017
cell recognition GO:0008037 85 0.017
negative regulation of nucleic acid templated transcription GO:1903507 53 0.017
Mouse
negative regulation of signaling GO:0023057 61 0.016
Mouse
regulation of cellular component organization GO:0051128 248 0.016
Fly
single organism behavior GO:0044708 83 0.016
response to mechanical stimulus GO:0009612 28 0.016
localization of cell GO:0051674 313 0.016
negative regulation of developmental process GO:0051093 227 0.015
collagen and cuticulin based cuticle development GO:0040002 99 0.015
regulation of localization GO:0032879 194 0.015
cuticle development GO:0042335 100 0.015
organelle fission GO:0048285 363 0.015
anatomical structure formation involved in morphogenesis GO:0048646 250 0.015
catabolic process GO:0009056 318 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
organic acid metabolic process GO:0006082 47 0.015
axon development GO:0061564 163 0.015
g1 s transition of mitotic cell cycle GO:0000082 2 0.015
cellular protein metabolic process GO:0044267 279 0.015
regulation of locomotion GO:0040012 161 0.015
neurological system process GO:0050877 53 0.015
regulation of ras protein signal transduction GO:0046578 41 0.015
oxoacid metabolic process GO:0043436 47 0.015
cell part morphogenesis GO:0032990 152 0.014
Fly
chemosensory behavior GO:0007635 33 0.014
cell cycle g1 s phase transition GO:0044843 2 0.014
tissue development GO:0009888 112 0.014
Mouse
regulation of organelle organization GO:0033043 164 0.014
protein modification process GO:0036211 207 0.014
macromolecule catabolic process GO:0009057 202 0.013
cellular response to abiotic stimulus GO:0071214 4 0.013
ribonucleoprotein complex assembly GO:0022618 4 0.013
intracellular receptor signaling pathway GO:0030522 2 0.013
axonal fasciculation GO:0007413 79 0.013
regulation of response to wounding GO:1903034 1 0.013
negative regulation of signal transduction GO:0009968 60 0.013
Mouse
organic substance transport GO:0071702 113 0.013
meiotic nuclear division GO:0007126 300 0.013
single organism organelle organization GO:1902589 501 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
macromolecular complex subunit organization GO:0043933 320 0.012
macromolecular complex assembly GO:0065003 193 0.012
adult behavior GO:0030534 3 0.012
protein complex biogenesis GO:0070271 186 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
secretion by cell GO:0032940 138 0.012
cellular catabolic process GO:0044248 199 0.012
regulation of mitotic cell cycle GO:0007346 76 0.012
turning behavior involved in mating GO:0034607 12 0.012
meiotic cell cycle process GO:1903046 170 0.012
protein catabolic process GO:0030163 162 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
positive regulation of metabolic process GO:0009893 187 0.012
Mouse
regulation of striated muscle contraction GO:0006942 4 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
regeneration GO:0031099 4 0.012
chemotaxis GO:0006935 120 0.012
chromosome segregation GO:0007059 180 0.012
skeletal muscle organ development GO:0060538 3 0.012
negative regulation of neurogenesis GO:0050768 4 0.012
inductive cell migration GO:0040039 145 0.012
meiotic chromosome segregation GO:0045132 139 0.012
organonitrogen compound catabolic process GO:1901565 90 0.012
defense response to other organism GO:0098542 100 0.011
hyperosmotic response GO:0006972 19 0.011
meiotic cell cycle GO:0051321 335 0.011
positive regulation of chromosome organization GO:2001252 2 0.011
protein complex assembly GO:0006461 186 0.011
response to temperature stimulus GO:0009266 66 0.011
regulation of cytoplasmic transport GO:1903649 3 0.011
single organism catabolic process GO:0044712 129 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
positive regulation of cellular biosynthetic process GO:0031328 109 0.011
Mouse
response to acid chemical GO:0001101 4 0.011
cellular protein modification process GO:0006464 207 0.011
chromatin remodeling GO:0006338 2 0.011
organ morphogenesis GO:0009887 67 0.011
Zebrafish
organelle assembly GO:0070925 214 0.011
myosin filament assembly GO:0031034 138 0.011
positive regulation of vulval development GO:0040026 52 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
positive regulation of nucleic acid templated transcription GO:1903508 102 0.011
Mouse
epithelial tube morphogenesis GO:0060562 1 0.011
innate immune response GO:0045087 190 0.011
regulation of small gtpase mediated signal transduction GO:0051056 41 0.011
positive regulation of gene expression GO:0010628 112 0.011
Mouse
protein complex subunit organization GO:0071822 280 0.010
adult locomotory behavior GO:0008344 1 0.010
regulation of cell death GO:0010941 65 0.010
negative regulation of transmembrane transport GO:0034763 3 0.010
cellular protein complex assembly GO:0043623 178 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
mitotic cell cycle process GO:1903047 194 0.010
pigmentation GO:0043473 2 0.010
negative regulation of ion transmembrane transport GO:0034766 3 0.010
posttranscriptional gene silencing by rna GO:0035194 143 0.010

egl-43 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.010