Caenorhabditis elegans

0 known processes

hil-3 (CELE_F22F1.1)

Protein HIL-3

hil-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.682
meiotic cell cycle process GO:1903046 170 0.587
embryo development ending in birth or egg hatching GO:0009792 2992 0.563
single fertilization GO:0007338 61 0.544
post embryonic development GO:0009791 2152 0.510
meiotic chromosome segregation GO:0045132 139 0.379
locomotion GO:0040011 1634 0.325
chromosome organization GO:0051276 104 0.300
Human
regulation of nematode larval development GO:0061062 260 0.265
multi organism reproductive process GO:0044703 867 0.256
Rat
multicellular organism reproduction GO:0032504 819 0.253
Rat
organ development GO:0048513 1102 0.245
Mouse
multicellular organismal reproductive process GO:0048609 815 0.245
Rat
multi organism reproductive behavior GO:0044705 387 0.239
meiotic nuclear division GO:0007126 300 0.230
developmental process involved in reproduction GO:0003006 1165 0.206
oviposition GO:0018991 364 0.198
regulation of meiotic cell cycle GO:0051445 136 0.195
negative regulation of macromolecule metabolic process GO:0010605 229 0.186
Human
cell cycle GO:0007049 526 0.179
chromosome segregation GO:0007059 180 0.178
sexual reproduction GO:0019953 546 0.171
Rat
gonad development GO:0008406 840 0.170
reproductive behavior GO:0019098 387 0.162
multi organism behavior GO:0051705 389 0.161
single organism reproductive process GO:0044702 1196 0.159
Rat
vesicle mediated transport GO:0016192 852 0.157
behavior GO:0007610 527 0.149
programmed cell death GO:0012501 500 0.147
endocytosis GO:0006897 819 0.140
regulation of gene expression GO:0010468 366 0.140
Human
gamete generation GO:0007276 461 0.140
Rat
cell development GO:0048468 696 0.139
cellular component movement GO:0006928 388 0.137
regulation of cellular biosynthetic process GO:0031326 189 0.136
Human
regulation of post embryonic development GO:0048580 260 0.135
organelle fission GO:0048285 363 0.135
multicellular organismal reproductive behavior GO:0033057 384 0.133
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.132
transcription dna templated GO:0006351 168 0.131
Human
receptor mediated endocytosis GO:0006898 715 0.127
negative regulation of biological process GO:0048519 567 0.124
Human
reproductive structure development GO:0048608 850 0.119
gene expression GO:0010467 412 0.119
Human
meiotic cell cycle GO:0051321 335 0.115
regulation of multicellular organismal process GO:0051239 726 0.115
development of primary sexual characteristics GO:0045137 840 0.114
dna metabolic process GO:0006259 74 0.114
transport GO:0006810 1093 0.113
multi multicellular organism process GO:0044706 390 0.112
cellular macromolecule biosynthetic process GO:0034645 247 0.102
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.102
Human
growth GO:0040007 562 0.100
Human
regulation of vulval development GO:0040028 248 0.092
establishment of localization GO:0051234 1171 0.092
Human
germ cell development GO:0007281 351 0.092
nucleobase containing compound biosynthetic process GO:0034654 184 0.091
Human
multicellular organismal aging GO:0010259 812 0.090
regulation of rna biosynthetic process GO:2001141 165 0.090
Human
negative regulation of metabolic process GO:0009892 240 0.088
Human
regulation of developmental process GO:0050793 684 0.087
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.086
Human
regulation of mitotic cell cycle GO:0007346 76 0.085
regulation of multicellular organismal development GO:2000026 317 0.083
single organism organelle organization GO:1902589 501 0.081
Human
chromatin assembly or disassembly GO:0006333 1 0.080
single organism behavior GO:0044708 83 0.080
vulval development GO:0040025 333 0.078
biosynthetic process GO:0009058 323 0.078
Human
protein dna complex subunit organization GO:0071824 7 0.078
body morphogenesis GO:0010171 620 0.076
chromatin organization GO:0006325 32 0.074
Human
nucleobase containing compound metabolic process GO:0006139 406 0.071
Human
negative regulation of developmental process GO:0051093 227 0.070
regulation of macromolecule metabolic process GO:0060255 421 0.069
Human
negative regulation of nematode larval development GO:0061064 208 0.069
positive regulation of cellular process GO:0048522 332 0.069
Human
cell motility GO:0048870 313 0.068
sex differentiation GO:0007548 909 0.068
hermaphrodite genitalia development GO:0040035 734 0.067
post embryonic organ development GO:0048569 336 0.066
apoptotic process GO:0006915 478 0.066
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.065
regulation of biological quality GO:0065008 741 0.064
Human
macromolecule localization GO:0033036 771 0.063
Human
negative regulation of post embryonic development GO:0048581 208 0.062
negative regulation of vulval development GO:0040027 206 0.062
aging GO:0007568 812 0.062
maintenance of location GO:0051235 580 0.061
head development GO:0060322 1 0.061
cell death GO:0008219 547 0.060
cell fate commitment GO:0045165 139 0.060
canonical wnt signaling pathway GO:0060070 3 0.060
sensory organ morphogenesis GO:0090596 2 0.059
regulation of gene expression epigenetic GO:0040029 163 0.059
protein metabolic process GO:0019538 422 0.058
Human
digestive tract development GO:0048565 122 0.057
reproductive system development GO:0061458 850 0.056
determination of adult lifespan GO:0008340 812 0.056
cellular component biogenesis GO:0044085 297 0.055
lipid storage GO:0019915 565 0.055
response to abiotic stimulus GO:0009628 152 0.055
defense response GO:0006952 296 0.055
rna biosynthetic process GO:0032774 169 0.054
Human
lipid localization GO:0010876 573 0.054
death GO:0016265 547 0.054
organic cyclic compound biosynthetic process GO:1901362 195 0.053
Human
negative regulation of cellular process GO:0048523 239 0.052
Human
genitalia development GO:0048806 741 0.051
cellular component assembly GO:0022607 293 0.050
aromatic compound biosynthetic process GO:0019438 192 0.050
Human
negative regulation of gene expression GO:0010629 217 0.049
Human
posttranscriptional regulation of gene expression GO:0010608 166 0.049
Human
protein complex subunit organization GO:0071822 280 0.049
response to chemical GO:0042221 356 0.049
negative regulation of mitotic cell cycle GO:0045930 42 0.048
organic substance biosynthetic process GO:1901576 323 0.047
Human
negative regulation of cell cycle GO:0045786 53 0.047
regulation of cell cycle GO:0051726 194 0.047
developmental growth GO:0048589 412 0.046
posttranscriptional gene silencing GO:0016441 143 0.046
organelle organization GO:0006996 783 0.046
Human
digestive system development GO:0055123 122 0.046
spermatogenesis GO:0007283 41 0.045
Rat
positive regulation of macromolecule metabolic process GO:0010604 149 0.045
Human
muscle cell development GO:0055001 158 0.045
muscle tissue development GO:0060537 1 0.045
cellular nitrogen compound biosynthetic process GO:0044271 192 0.044
Human
rna metabolic process GO:0016070 228 0.044
Human
macromolecule biosynthetic process GO:0009059 250 0.042
Human
regulation of cellular protein metabolic process GO:0032268 75 0.042
Human
cell migration GO:0016477 306 0.041
gene silencing GO:0016458 143 0.040
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.040
Human
regulation of metabolic process GO:0019222 478 0.040
Human
immune response GO:0006955 192 0.039
dna conformation change GO:0071103 11 0.038
positive regulation of cell cycle GO:0045787 55 0.038
negative regulation of multicellular organismal process GO:0051241 236 0.037
nucleic acid metabolic process GO:0090304 299 0.037
Human
cell cycle process GO:0022402 482 0.037
nucleic acid templated transcription GO:0097659 169 0.037
Human
cellular protein metabolic process GO:0044267 279 0.036
Human
cellular biosynthetic process GO:0044249 315 0.036
Human
negative regulation of cellular biosynthetic process GO:0031327 65 0.036
Human
striated muscle cell differentiation GO:0051146 158 0.035
response to wounding GO:0009611 4 0.035
posttranscriptional gene silencing by rna GO:0035194 143 0.035
cellular protein modification process GO:0006464 207 0.034
Human
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 35 0.034
gene silencing by rna GO:0031047 143 0.034
regulation of nitrogen compound metabolic process GO:0051171 222 0.033
Human
positive regulation of cellular metabolic process GO:0031325 178 0.033
Human
macromolecule modification GO:0043412 218 0.033
Human
skeletal muscle organ development GO:0060538 3 0.032
negative regulation of biosynthetic process GO:0009890 65 0.032
Human
intracellular receptor signaling pathway GO:0030522 2 0.032
macromolecular complex assembly GO:0065003 193 0.031
spindle organization GO:0007051 92 0.031
regulation of cellular metabolic process GO:0031323 305 0.031
Human
signal transduction GO:0007165 317 0.030
cellular component morphogenesis GO:0032989 318 0.030
negative regulation of cellular metabolic process GO:0031324 95 0.030
Human
positive regulation of meiotic cell cycle GO:0051446 47 0.029
rna interference GO:0016246 137 0.029
dna packaging GO:0006323 7 0.029
tissue development GO:0009888 112 0.029
organelle localization GO:0051640 127 0.029
positive regulation of rna metabolic process GO:0051254 103 0.029
epithelium development GO:0060429 68 0.028
positive regulation of developmental growth GO:0048639 354 0.028
regulation of multicellular organism growth GO:0040014 373 0.028
male gamete generation GO:0048232 41 0.028
Rat
transcription from rna polymerase ii promoter GO:0006366 149 0.027
Human
wnt signaling pathway GO:0016055 27 0.027
regulation of growth GO:0040008 409 0.027
Human
cellular response to stress GO:0033554 162 0.027
negative regulation of cell communication GO:0010648 61 0.027
neuron projection guidance GO:0097485 82 0.026
regulation of developmental growth GO:0048638 389 0.026
cytoskeleton organization GO:0007010 339 0.026
positive regulation of epithelial cell proliferation GO:0050679 1 0.026
positive regulation of multicellular organism growth GO:0040018 352 0.026
positive regulation of rna biosynthetic process GO:1902680 102 0.026
regulation of response to stimulus GO:0048583 243 0.026
heterocycle biosynthetic process GO:0018130 187 0.026
Human
regeneration GO:0031099 4 0.025
multicellular organism growth GO:0035264 385 0.025
regulation of cell communication GO:0010646 176 0.024
muscle structure development GO:0061061 191 0.024
Mouse
neuron projection development GO:0031175 187 0.024
positive regulation of multicellular organismal process GO:0051240 417 0.024
regulation of biosynthetic process GO:0009889 189 0.024
Human
taxis GO:0042330 128 0.024
muscle fiber development GO:0048747 2 0.024
macromolecular complex subunit organization GO:0043933 320 0.023
Human
cell part morphogenesis GO:0032990 152 0.023
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.023
chemotaxis GO:0006935 120 0.023
cell division GO:0051301 262 0.023
cellular response to topologically incorrect protein GO:0035967 76 0.023
single organism signaling GO:0044700 401 0.023
localization of cell GO:0051674 313 0.023
regulation of protein metabolic process GO:0051246 81 0.022
Human
regulation of nucleic acid templated transcription GO:1903506 165 0.022
Human
cell recognition GO:0008037 85 0.022
regulation of cellular component organization GO:0051128 248 0.022
Human
homeostatic process GO:0042592 51 0.022
inductive cell migration GO:0040039 145 0.022
regulation of organelle organization GO:0033043 164 0.022
Human
myofibril assembly GO:0030239 154 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.022
positive regulation of developmental process GO:0051094 408 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.021
Human
epithelial cell proliferation GO:0050673 1 0.021
oocyte axis specification GO:0007309 2 0.021
aromatic compound catabolic process GO:0019439 116 0.020
muscle cell differentiation GO:0042692 171 0.020
feeding behavior GO:0007631 70 0.020
regulation of signal transduction GO:0009966 135 0.020
regulation of intracellular signal transduction GO:1902531 77 0.020
positive regulation of nucleic acid templated transcription GO:1903508 102 0.020
negative regulation of nucleic acid templated transcription GO:1903507 53 0.020
Human
cell morphogenesis GO:0000902 163 0.020
positive regulation of metabolic process GO:0009893 187 0.020
Human
negative regulation of response to stimulus GO:0048585 73 0.020
organic cyclic compound catabolic process GO:1901361 119 0.020
embryonic morphogenesis GO:0048598 152 0.020
cellular amino acid metabolic process GO:0006520 15 0.020
signaling GO:0023052 401 0.019
regulation of cell fate specification GO:0042659 22 0.019
catabolic process GO:0009056 318 0.019
molting cycle GO:0042303 281 0.019
cell projection organization GO:0030030 231 0.019
protein modification process GO:0036211 207 0.019
Human
regulation of cellular ketone metabolic process GO:0010565 3 0.019
single organism transport GO:0044765 447 0.019
cell proliferation GO:0008283 116 0.019
cellular nitrogen compound catabolic process GO:0044270 119 0.018
negative regulation of signal transduction GO:0009968 60 0.018
response to external stimulus GO:0009605 289 0.018
striated muscle cell development GO:0055002 157 0.018
adult behavior GO:0030534 3 0.018
mechanosensory behavior GO:0007638 25 0.018
macromolecule catabolic process GO:0009057 202 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
positive regulation of signaling GO:0023056 66 0.018
cell surface receptor signaling pathway GO:0007166 149 0.017
positive regulation of transcription dna templated GO:0045893 102 0.017
regulation of transcription dna templated GO:0006355 164 0.017
Human
fertilization GO:0009566 63 0.017
chemosensory behavior GO:0007635 33 0.017
establishment of localization in cell GO:0051649 318 0.017
mrna metabolic process GO:0016071 31 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.017
Human
translation GO:0006412 37 0.016
nucleobase containing compound catabolic process GO:0034655 114 0.016
intracellular signal transduction GO:0035556 96 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.016
Human
adult locomotory behavior GO:0008344 1 0.016
female gamete generation GO:0007292 254 0.016
positive regulation of growth GO:0045927 369 0.016
Human
negative regulation of rna biosynthetic process GO:1902679 53 0.016
Human
negative regulation of transcription dna templated GO:0045892 53 0.016
Human
cellular amine metabolic process GO:0044106 15 0.016
regulation of signaling GO:0023051 172 0.016
carboxylic acid metabolic process GO:0019752 34 0.016
protein complex assembly GO:0006461 186 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.015
negative regulation of neuron differentiation GO:0045665 4 0.015
rrna processing GO:0006364 3 0.015
negative regulation of rna metabolic process GO:0051253 53 0.015
Human
microtubule based process GO:0007017 182 0.015
chromatin remodeling GO:0006338 2 0.015
neuron development GO:0048666 199 0.015
mitotic cell cycle process GO:1903047 194 0.015
anatomical structure formation involved in morphogenesis GO:0048646 250 0.015
translational initiation GO:0006413 2 0.015
ribosome biogenesis GO:0042254 4 0.015
regulation of locomotion GO:0040012 161 0.015
axon guidance GO:0007411 82 0.015
actin cytoskeleton organization GO:0030036 184 0.015
single organism localization GO:1902578 518 0.014
negative regulation of gene expression epigenetic GO:0045814 2 0.014
establishment of mitotic spindle localization GO:0040001 41 0.014
regulation of response to wounding GO:1903034 1 0.014
negative regulation of response to external stimulus GO:0032102 3 0.014
innate immune response GO:0045087 190 0.014
system process GO:0003008 136 0.014
regulation of cell fate commitment GO:0010453 22 0.014
response to topologically incorrect protein GO:0035966 82 0.014
cellular localization GO:0051641 360 0.014
Human
collagen and cuticulin based cuticle development GO:0040002 99 0.014
atp metabolic process GO:0046034 42 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.014
Human
chromatin assembly GO:0031497 1 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.014
organic substance catabolic process GO:1901575 294 0.014
actomyosin structure organization GO:0031032 154 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
apical junction assembly GO:0043297 1 0.013
amine metabolic process GO:0009308 15 0.013
cell cycle switching GO:0060184 35 0.013
neuromuscular process GO:0050905 1 0.013
cell type specific apoptotic process GO:0097285 4 0.013
organonitrogen compound metabolic process GO:1901564 151 0.013
cellular component assembly involved in morphogenesis GO:0010927 183 0.013
protein localization GO:0008104 205 0.013
Human
rna processing GO:0006396 34 0.013
positive regulation of phosphorus metabolic process GO:0010562 56 0.013
organic acid metabolic process GO:0006082 47 0.013
purine nucleoside triphosphate metabolic process GO:0009144 87 0.013
organelle assembly GO:0070925 214 0.013
regulation of primary metabolic process GO:0080090 292 0.013
Human
neuron recognition GO:0008038 83 0.013
phosphorus metabolic process GO:0006793 232 0.012
response to heat GO:0009408 50 0.012
response to endoplasmic reticulum stress GO:0034976 71 0.012
regionalization GO:0003002 31 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
response to temperature stimulus GO:0009266 66 0.012
cuticle development GO:0042335 100 0.012
regulation of localization GO:0032879 194 0.012
olfactory behavior GO:0042048 27 0.012
nervous system development GO:0007399 253 0.012
myosin filament assembly GO:0031034 138 0.012
protein complex biogenesis GO:0070271 186 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
chromatin modification GO:0016568 32 0.012
Human
cellular catabolic process GO:0044248 199 0.011
generation of neurons GO:0048699 235 0.011
small molecule metabolic process GO:0044281 186 0.011
protein modification by small protein conjugation or removal GO:0070647 40 0.011
regulation of epithelial cell proliferation GO:0050678 1 0.011
proximal distal pattern formation GO:0009954 6 0.011
negative regulation of signaling GO:0023057 61 0.011
internal peptidyl lysine acetylation GO:0018393 3 0.011
er nucleus signaling pathway GO:0006984 66 0.011
regulation of cell motility GO:2000145 57 0.011
mitotic spindle organization GO:0007052 81 0.011
regulation of organ morphogenesis GO:2000027 4 0.011
cellular response to abiotic stimulus GO:0071214 4 0.011
establishment of nucleus localization GO:0040023 55 0.011
regulation of bmp signaling pathway GO:0030510 3 0.011
heterocycle catabolic process GO:0046700 119 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.011
Human
cellular response to dna damage stimulus GO:0006974 41 0.011
negative chemotaxis GO:0050919 1 0.011
cellular ketone metabolic process GO:0042180 14 0.011
neuromuscular junction development GO:0007528 2 0.011
asymmetric cell division GO:0008356 36 0.010
oogenesis GO:0048477 229 0.010
hormone transport GO:0009914 2 0.010
endoplasmic reticulum unfolded protein response GO:0030968 66 0.010
tube development GO:0035295 126 0.010

hil-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of metabolism DOID:0014667 0 0.012
nervous system disease DOID:863 0 0.012