Caenorhabditis elegans

28 known processes

pas-6 (CELE_CD4.6)

Protein PAS-6

pas-6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.746
single organism reproductive process GO:0044702 1196 0.733
post embryonic development GO:0009791 2152 0.609
cell death GO:0008219 547 0.596
protein catabolic process GO:0030163 162 0.592
Yeast
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.557
programmed cell death GO:0012501 500 0.506
embryo development GO:0009790 3052 0.491
modification dependent protein catabolic process GO:0019941 32 0.473
Yeast
apoptotic process GO:0006915 478 0.434
multicellular organismal aging GO:0010259 812 0.432
death GO:0016265 547 0.394
aging GO:0007568 812 0.351
modification dependent macromolecule catabolic process GO:0043632 32 0.341
Yeast
establishment of localization in cell GO:0051649 318 0.325
cellular response to stress GO:0033554 162 0.316
fertilization GO:0009566 63 0.315
catabolic process GO:0009056 318 0.308
Yeast
organ development GO:0048513 1102 0.302
organic substance catabolic process GO:1901575 294 0.291
Yeast
signal transduction GO:0007165 317 0.289
single fertilization GO:0007338 61 0.289
locomotion GO:0040011 1634 0.287
negative regulation of biological process GO:0048519 567 0.282
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.272
nucleobase containing compound biosynthetic process GO:0034654 184 0.269
regulation of biosynthetic process GO:0009889 189 0.266
gene expression GO:0010467 412 0.266
pronuclear migration GO:0035046 51 0.265
sexual reproduction GO:0019953 546 0.250
proteasome assembly GO:0043248 1 0.249
cellular macromolecule biosynthetic process GO:0034645 247 0.242
cellular biosynthetic process GO:0044249 315 0.227
determination of adult lifespan GO:0008340 812 0.225
mitotic cell cycle process GO:1903047 194 0.222
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.221
Yeast
organic substance biosynthetic process GO:1901576 323 0.219
heterocycle biosynthetic process GO:0018130 187 0.215
regulation of response to stimulus GO:0048583 243 0.215
Mouse
ubiquitin dependent protein catabolic process GO:0006511 32 0.210
Yeast
positive regulation of rna biosynthetic process GO:1902680 102 0.199
transport GO:0006810 1093 0.198
regulation of transcription dna templated GO:0006355 164 0.196
cytoskeleton organization GO:0007010 339 0.193
regulation of macromolecule metabolic process GO:0060255 421 0.186
receptor mediated endocytosis GO:0006898 715 0.185
regulation of metabolic process GO:0019222 478 0.181
signaling GO:0023052 401 0.178
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.175
endocytosis GO:0006897 819 0.173
positive regulation of transcription dna templated GO:0045893 102 0.172
vesicle mediated transport GO:0016192 852 0.170
positive regulation of cellular process GO:0048522 332 0.170
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.168
organelle assembly GO:0070925 214 0.163
macromolecule localization GO:0033036 771 0.160
regulation of gene expression GO:0010468 366 0.158
regulation of cellular metabolic process GO:0031323 305 0.155
nervous system development GO:0007399 253 0.151
regulation of macromolecule biosynthetic process GO:0010556 189 0.150
positive regulation of cellular metabolic process GO:0031325 178 0.146
cell cycle process GO:0022402 482 0.144
cellular protein metabolic process GO:0044267 279 0.140
Yeast
regulation of signaling GO:0023051 172 0.140
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.140
mitotic nuclear division GO:0007067 89 0.134
organic cyclic compound biosynthetic process GO:1901362 195 0.132
cell motility GO:0048870 313 0.129
development of primary sexual characteristics GO:0045137 840 0.128
cellular protein catabolic process GO:0044257 37 0.128
Yeast
gamete generation GO:0007276 461 0.124
regulation of biological quality GO:0065008 741 0.124
actin filament based process GO:0030029 191 0.119
organelle organization GO:0006996 783 0.116
positive regulation of biosynthetic process GO:0009891 109 0.113
gonad development GO:0008406 840 0.113
transcription from rna polymerase ii promoter GO:0006366 149 0.111
response to abiotic stimulus GO:0009628 152 0.111
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.110
Yeast
cell migration GO:0016477 306 0.109
cellular localization GO:0051641 360 0.109
response to chemical GO:0042221 356 0.109
macromolecule catabolic process GO:0009057 202 0.108
Yeast
regulation of cellular biosynthetic process GO:0031326 189 0.108
positive regulation of nucleic acid templated transcription GO:1903508 102 0.107
cell development GO:0048468 696 0.104
establishment of localization GO:0051234 1171 0.103
nucleic acid templated transcription GO:0097659 169 0.103
intracellular signal transduction GO:0035556 96 0.102
positive regulation of cellular biosynthetic process GO:0031328 109 0.102
rna metabolic process GO:0016070 228 0.100
reproductive system development GO:0061458 850 0.096
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.095
neurogenesis GO:0022008 236 0.095
developmental process involved in reproduction GO:0003006 1165 0.094
genitalia development GO:0048806 741 0.094
single organism signaling GO:0044700 401 0.093
centrosomal and pronuclear rotation GO:0035047 6 0.092
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.091
regulation of nucleic acid templated transcription GO:1903506 165 0.091
aromatic compound biosynthetic process GO:0019438 192 0.089
reproductive structure development GO:0048608 850 0.089
cell cycle GO:0007049 526 0.089
protein complex subunit organization GO:0071822 280 0.089
positive regulation of macromolecule metabolic process GO:0010604 149 0.089
proteolysis GO:0006508 61 0.088
Yeast
regulation of rna metabolic process GO:0051252 173 0.088
body morphogenesis GO:0010171 620 0.087
hermaphrodite genitalia development GO:0040035 734 0.086
response to topologically incorrect protein GO:0035966 82 0.086
rna biosynthetic process GO:0032774 169 0.085
protein complex assembly GO:0006461 186 0.084
regulation of rna biosynthetic process GO:2001141 165 0.083
cellular protein complex assembly GO:0043623 178 0.082
multicellular organismal reproductive process GO:0048609 815 0.080
meiotic cell cycle GO:0051321 335 0.080
regulation of cell communication GO:0010646 176 0.080
regulation of localization GO:0032879 194 0.079
growth GO:0040007 562 0.079
er associated misfolded protein catabolic process GO:0071712 4 0.079
regulation of multicellular organismal process GO:0051239 726 0.079
regulation of primary metabolic process GO:0080090 292 0.078
maintenance of location GO:0051235 580 0.078
multicellular organism growth GO:0035264 385 0.077
response to organic substance GO:0010033 131 0.077
regulation of growth GO:0040008 409 0.077
multi organism reproductive process GO:0044703 867 0.077
germ cell development GO:0007281 351 0.075
positive regulation of developmental process GO:0051094 408 0.075
macromolecular complex subunit organization GO:0043933 320 0.074
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.073
cellular response to topologically incorrect protein GO:0035967 76 0.073
lipid localization GO:0010876 573 0.072
protein metabolic process GO:0019538 422 0.072
Yeast
macromolecular complex assembly GO:0065003 193 0.071
cellular response to chemical stimulus GO:0070887 129 0.070
protein complex biogenesis GO:0070271 186 0.069
cellular component assembly GO:0022607 293 0.069
lipid storage GO:0019915 565 0.069
cell proliferation GO:0008283 116 0.069
secretion by cell GO:0032940 138 0.068
secretion GO:0046903 147 0.067
er associated ubiquitin dependent protein catabolic process GO:0030433 6 0.067
cellular component morphogenesis GO:0032989 318 0.067
cellular macromolecule catabolic process GO:0044265 73 0.065
Yeast
positive regulation of metabolic process GO:0009893 187 0.063
regulation of nitrogen compound metabolic process GO:0051171 222 0.061
cellular nitrogen compound biosynthetic process GO:0044271 192 0.059
sex differentiation GO:0007548 909 0.059
golgi vesicle transport GO:0048193 3 0.059
regulation of intracellular signal transduction GO:1902531 77 0.058
developmental growth GO:0048589 412 0.058
regulation of developmental process GO:0050793 684 0.056
intracellular receptor signaling pathway GO:0030522 2 0.056
posttranscriptional regulation of gene expression GO:0010608 166 0.055
pole plasm assembly GO:0007315 2 0.054
multicellular organism reproduction GO:0032504 819 0.053
muscle cell differentiation GO:0042692 171 0.052
oocyte axis specification GO:0007309 2 0.052
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.050
female gamete generation GO:0007292 254 0.048
striated muscle cell development GO:0055002 157 0.048
positive regulation of multicellular organism growth GO:0040018 352 0.048
response to external stimulus GO:0009605 289 0.048
Mouse
regulation of developmental growth GO:0048638 389 0.048
oogenesis GO:0048477 229 0.048
macromolecule biosynthetic process GO:0009059 250 0.048
multicellular organismal reproductive behavior GO:0033057 384 0.048
response to wounding GO:0009611 4 0.047
Mouse
sensory organ morphogenesis GO:0090596 2 0.046
actin cytoskeleton organization GO:0030036 184 0.046
transcription dna templated GO:0006351 168 0.046
positive regulation of developmental growth GO:0048639 354 0.046
negative regulation of multicellular organismal process GO:0051241 236 0.046
regulation of signal transduction GO:0009966 135 0.045
negative regulation of developmental process GO:0051093 227 0.045
anatomical structure formation involved in morphogenesis GO:0048646 250 0.045
positive regulation of rna metabolic process GO:0051254 103 0.044
protein localization GO:0008104 205 0.044
small molecule metabolic process GO:0044281 186 0.044
regulation of multicellular organism growth GO:0040014 373 0.043
muscle structure development GO:0061061 191 0.043
meiotic cell cycle process GO:1903046 170 0.043
negative regulation of metabolic process GO:0009892 240 0.039
nucleobase containing compound metabolic process GO:0006139 406 0.038
actomyosin structure organization GO:0031032 154 0.038
response to bacterium GO:0009617 86 0.038
behavior GO:0007610 527 0.038
molting cycle GO:0042303 281 0.038
neuron development GO:0048666 199 0.038
establishment of organelle localization GO:0051656 123 0.037
striated muscle cell differentiation GO:0051146 158 0.037
cellular component biogenesis GO:0044085 297 0.037
mitotic spindle organization GO:0007052 81 0.037
biosynthetic process GO:0009058 323 0.036
response to external biotic stimulus GO:0043207 101 0.036
head development GO:0060322 1 0.036
cellular protein modification process GO:0006464 207 0.035
single organism organelle organization GO:1902589 501 0.035
organophosphate metabolic process GO:0019637 125 0.035
negative regulation of gene expression GO:0010629 217 0.035
negative regulation of cellular process GO:0048523 239 0.034
cellular catabolic process GO:0044248 199 0.034
Yeast
proteasomal protein catabolic process GO:0010498 20 0.034
Yeast
cellular component assembly involved in morphogenesis GO:0010927 183 0.034
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.034
positive regulation of gene expression GO:0010628 112 0.034
oocyte construction GO:0007308 2 0.033
localization of cell GO:0051674 313 0.033
dauer larval development GO:0040024 92 0.032
asymmetric protein localization GO:0008105 35 0.032
myofibril assembly GO:0030239 154 0.032
nucleic acid metabolic process GO:0090304 299 0.031
nucleotide metabolic process GO:0009117 108 0.031
carboxylic acid metabolic process GO:0019752 34 0.031
establishment of nucleus localization GO:0040023 55 0.031
cell type specific apoptotic process GO:0097285 4 0.031
atp metabolic process GO:0046034 42 0.030
p38mapk cascade GO:0038066 2 0.030
striated muscle myosin thick filament assembly GO:0071688 138 0.030
misfolded or incompletely synthesized protein catabolic process GO:0006515 4 0.030
regulation of transport GO:0051049 91 0.030
organonitrogen compound metabolic process GO:1901564 151 0.029
organelle fission GO:0048285 363 0.029
nucleoside triphosphate catabolic process GO:0009143 72 0.029
generation of neurons GO:0048699 235 0.028
single organism transport GO:0044765 447 0.028
intracellular transport GO:0046907 77 0.028
rna localization GO:0006403 3 0.028
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.028
regulation of apoptotic signaling pathway GO:2001233 1 0.028
regulation of molecular function GO:0065009 89 0.028
spindle organization GO:0007051 92 0.027
regulation of locomotion GO:0040012 161 0.027
carbohydrate derivative metabolic process GO:1901135 141 0.027
negative regulation of bmp signaling pathway GO:0030514 1 0.027
negative regulation of response to stimulus GO:0048585 73 0.027
Mouse
single organism localization GO:1902578 518 0.026
cellular response to misfolded protein GO:0071218 7 0.026
positive regulation of multicellular organismal process GO:0051240 417 0.026
gene silencing GO:0016458 143 0.025
collagen and cuticulin based cuticle development GO:0040002 99 0.025
macromolecule modification GO:0043412 218 0.025
regulation of protein ubiquitination GO:0031396 3 0.025
atp catabolic process GO:0006200 27 0.025
myosin filament assembly GO:0031034 138 0.025
myosin filament organization GO:0031033 138 0.025
response to heat GO:0009408 50 0.025
meiotic nuclear division GO:0007126 300 0.024
nuclear migration GO:0007097 54 0.024
organelle localization GO:0051640 127 0.024
vulval development GO:0040025 333 0.023
homeostatic process GO:0042592 51 0.023
positive regulation of growth GO:0045927 369 0.023
regulation of apoptotic process GO:0042981 36 0.023
nucleus localization GO:0051647 55 0.022
cellular component movement GO:0006928 388 0.022
meiotic chromosome segregation GO:0045132 139 0.022
protein refolding GO:0042026 1 0.022
muscle cell development GO:0055001 158 0.022
response to temperature stimulus GO:0009266 66 0.022
innate immune response GO:0045087 190 0.021
rna interference GO:0016246 137 0.021
organic substance transport GO:0071702 113 0.021
phosphorus metabolic process GO:0006793 232 0.021
neuromuscular process GO:0050905 1 0.021
cellular macromolecular complex assembly GO:0034622 184 0.021
heterocycle catabolic process GO:0046700 119 0.021
regulation of behavior GO:0050795 97 0.020
dna templated transcription initiation GO:0006352 3 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.020
ribonucleoprotein complex assembly GO:0022618 4 0.020
purine nucleoside metabolic process GO:0042278 92 0.019
cellular response to organic substance GO:0071310 119 0.019
organic acid metabolic process GO:0006082 47 0.019
single organism carbohydrate metabolic process GO:0044723 29 0.019
reproductive behavior GO:0019098 387 0.019
cuticle development GO:0042335 100 0.019
cellular response to dna damage stimulus GO:0006974 41 0.018
pigmentation GO:0043473 2 0.018
response to biotic stimulus GO:0009607 101 0.018
oxidation reduction process GO:0055114 59 0.018
negative regulation of cell communication GO:0010648 61 0.018
neurological system process GO:0050877 53 0.017
positive regulation of signaling GO:0023056 66 0.017
digestive tract development GO:0048565 122 0.017
oxoacid metabolic process GO:0043436 47 0.017
cellular response to unfolded protein GO:0034620 71 0.017
microtubule based process GO:0007017 182 0.017
defense response GO:0006952 296 0.017
Mouse
regeneration GO:0031099 4 0.017
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.017
axon development GO:0061564 163 0.017
establishment of rna localization GO:0051236 3 0.016
purine nucleotide metabolic process GO:0006163 95 0.016
negative regulation of macromolecule metabolic process GO:0010605 229 0.016
single organism intracellular transport GO:1902582 70 0.016
response to inorganic substance GO:0010035 50 0.016
regulation of cell differentiation GO:0045595 81 0.016
cellular nitrogen compound catabolic process GO:0044270 119 0.016
multi multicellular organism process GO:0044706 390 0.016
immune response GO:0006955 192 0.016
Mouse
cellular amino acid metabolic process GO:0006520 15 0.016
basement membrane organization GO:0071711 3 0.016
regulation of cell death GO:0010941 65 0.016
male gamete generation GO:0048232 41 0.015
multi organism behavior GO:0051705 389 0.015
response to other organism GO:0051707 101 0.015
positive regulation of epithelial cell proliferation GO:0050679 1 0.015
regulation of catalytic activity GO:0050790 78 0.015
regulation of cell proliferation GO:0042127 105 0.015
response to unfolded protein GO:0006986 71 0.015
post embryonic organ development GO:0048569 336 0.015
nucleic acid transport GO:0050657 3 0.015
nucleoside monophosphate metabolic process GO:0009123 46 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.015
stress activated protein kinase signaling cascade GO:0031098 10 0.014
protein modification process GO:0036211 207 0.014
response to oxygen containing compound GO:1901700 44 0.014
purine containing compound metabolic process GO:0072521 95 0.014
regulation of programmed cell death GO:0043067 50 0.014
stress activated mapk cascade GO:0051403 10 0.014
protein localization to mitochondrion GO:0070585 2 0.014
oviposition GO:0018991 364 0.014
protein modification by small protein conjugation or removal GO:0070647 40 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
regulation of post embryonic development GO:0048580 260 0.014
cellular lipid metabolic process GO:0044255 40 0.014
regulation of cellular localization GO:0060341 42 0.013
chromosome segregation GO:0007059 180 0.013
gene silencing by rna GO:0031047 143 0.013
system process GO:0003008 136 0.013
negative regulation of programmed cell death GO:0043069 19 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
positive regulation of apoptotic process GO:0043065 17 0.013
single organism catabolic process GO:0044712 129 0.013
positive regulation of cell communication GO:0010647 69 0.013
establishment or maintenance of cell polarity GO:0007163 63 0.012
inductive cell migration GO:0040039 145 0.012
regulation of cell cycle GO:0051726 194 0.012
regulation of jun kinase activity GO:0043506 3 0.012
endoplasmic reticulum unfolded protein response GO:0030968 66 0.012
cellular response to inorganic substance GO:0071241 3 0.012
regulation of cytoplasmic transport GO:1903649 3 0.012
organophosphate catabolic process GO:0046434 81 0.012
ribonucleoside triphosphate metabolic process GO:0009199 87 0.012
response to metal ion GO:0010038 33 0.012
regulation of response to wounding GO:1903034 1 0.012
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
defense response to bacterium GO:0042742 86 0.011
er nucleus signaling pathway GO:0006984 66 0.011
dna templated transcription elongation GO:0006354 1 0.011
positive regulation of cell migration GO:0030335 3 0.011
establishment of mitotic spindle orientation GO:0000132 28 0.011
negative regulation of signal transduction GO:0009968 60 0.011
tube development GO:0035295 126 0.011
negative regulation of vulval development GO:0040027 206 0.011
protein dna complex subunit organization GO:0071824 7 0.011
protein ubiquitination GO:0016567 25 0.011
negative regulation of nematode larval development GO:0061064 208 0.011
phosphate containing compound metabolic process GO:0006796 232 0.011
cell recognition GO:0008037 85 0.011
protein modification by small protein conjugation GO:0032446 31 0.011
ribonucleoside triphosphate catabolic process GO:0009203 72 0.011
regulation of vulval development GO:0040028 248 0.011
nucleobase containing compound catabolic process GO:0034655 114 0.011
purine ribonucleotide metabolic process GO:0009150 95 0.011
defense response to other organism GO:0098542 100 0.010
spermatogenesis GO:0007283 41 0.010
single organism cellular localization GO:1902580 72 0.010
regulation of lipid biosynthetic process GO:0046890 1 0.010
protein transport GO:0015031 45 0.010
tissue development GO:0009888 112 0.010
regulation of stress activated protein kinase signaling cascade GO:0070302 5 0.010
ribonucleotide metabolic process GO:0009259 99 0.010

pas-6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
neuromuscular disease DOID:440 0 0.014
charcot marie tooth disease type 2 DOID:0050539 0 0.014
charcot marie tooth disease DOID:10595 0 0.014
nervous system disease DOID:863 0 0.014
neuropathy DOID:870 0 0.014