Caenorhabditis elegans

0 known processes

rop-1 (CELE_C12D8.11)

Protein ROP-1

rop-1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.625
establishment of localization GO:0051234 1171 0.366
post embryonic development GO:0009791 2152 0.284
embryo development ending in birth or egg hatching GO:0009792 2992 0.278
transport GO:0006810 1093 0.274
vesicle mediated transport GO:0016192 852 0.263
locomotion GO:0040011 1634 0.247
receptor mediated endocytosis GO:0006898 715 0.230
regulation of biological quality GO:0065008 741 0.179
single organism reproductive process GO:0044702 1196 0.173
multicellular organism reproduction GO:0032504 819 0.157
germ cell development GO:0007281 351 0.142
developmental process involved in reproduction GO:0003006 1165 0.135
sex differentiation GO:0007548 909 0.125
regulation of multicellular organismal process GO:0051239 726 0.122
reproductive structure development GO:0048608 850 0.121
single organism transport GO:0044765 447 0.112
multi organism reproductive process GO:0044703 867 0.110
growth GO:0040007 562 0.106
negative regulation of biological process GO:0048519 567 0.103
cell development GO:0048468 696 0.099
multicellular organismal aging GO:0010259 812 0.099
organelle organization GO:0006996 783 0.097
programmed cell death GO:0012501 500 0.093
organ development GO:0048513 1102 0.092
lipid localization GO:0010876 573 0.085
reproductive system development GO:0061458 850 0.085
defense response GO:0006952 296 0.084
body morphogenesis GO:0010171 620 0.083
response to chemical GO:0042221 356 0.082
macromolecule localization GO:0033036 771 0.082
behavior GO:0007610 527 0.081
establishment of organelle localization GO:0051656 123 0.079
regulation of developmental process GO:0050793 684 0.078
maintenance of location GO:0051235 580 0.073
determination of adult lifespan GO:0008340 812 0.072
lipid storage GO:0019915 565 0.072
single organism localization GO:1902578 518 0.070
death GO:0016265 547 0.068
regulation of multicellular organismal development GO:2000026 317 0.064
nucleobase containing compound metabolic process GO:0006139 406 0.064
apoptotic process GO:0006915 478 0.063
sexual reproduction GO:0019953 546 0.062
multicellular organismal reproductive process GO:0048609 815 0.061
gamete generation GO:0007276 461 0.061
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.061
endocytosis GO:0006897 819 0.056
single organism signaling GO:0044700 401 0.054
Mouse
organelle fission GO:0048285 363 0.054
regulation of developmental growth GO:0048638 389 0.054
negative regulation of cellular process GO:0048523 239 0.054
macromolecule modification GO:0043412 218 0.053
cell division GO:0051301 262 0.053
regulation of macromolecule metabolic process GO:0060255 421 0.052
hermaphrodite genitalia development GO:0040035 734 0.051
multicellular organism growth GO:0035264 385 0.051
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.051
genitalia development GO:0048806 741 0.050
regulation of post embryonic development GO:0048580 260 0.050
small molecule metabolic process GO:0044281 186 0.049
response to external stimulus GO:0009605 289 0.049
gonad development GO:0008406 840 0.049
aging GO:0007568 812 0.049
meiotic nuclear division GO:0007126 300 0.049
multicellular organismal reproductive behavior GO:0033057 384 0.047
regulation of metabolic process GO:0019222 478 0.047
protein metabolic process GO:0019538 422 0.046
organic substance biosynthetic process GO:1901576 323 0.046
anatomical structure formation involved in morphogenesis GO:0048646 250 0.046
cell cycle process GO:0022402 482 0.045
multi organism reproductive behavior GO:0044705 387 0.044
cell death GO:0008219 547 0.044
development of primary sexual characteristics GO:0045137 840 0.044
phagocytosis GO:0006909 115 0.043
cellular biosynthetic process GO:0044249 315 0.043
oogenesis GO:0048477 229 0.043
regulation of growth GO:0040008 409 0.043
positive regulation of multicellular organismal process GO:0051240 417 0.043
reproductive behavior GO:0019098 387 0.042
negative regulation of nematode larval development GO:0061064 208 0.042
meiotic cell cycle GO:0051321 335 0.042
female gamete generation GO:0007292 254 0.041
molting cycle GO:0042303 281 0.041
positive regulation of growth GO:0045927 369 0.040
biosynthetic process GO:0009058 323 0.040
posttranscriptional regulation of gene expression GO:0010608 166 0.039
response to biotic stimulus GO:0009607 101 0.039
negative regulation of metabolic process GO:0009892 240 0.039
regulation of nematode larval development GO:0061062 260 0.039
gene expression GO:0010467 412 0.039
organic acid metabolic process GO:0006082 47 0.039
sensory organ morphogenesis GO:0090596 2 0.038
oviposition GO:0018991 364 0.037
protein modification process GO:0036211 207 0.037
multi organism behavior GO:0051705 389 0.037
regulation of multicellular organism growth GO:0040014 373 0.037
post embryonic organ development GO:0048569 336 0.036
developmental growth GO:0048589 412 0.036
multi multicellular organism process GO:0044706 390 0.036
cell cycle GO:0007049 526 0.036
cellular protein metabolic process GO:0044267 279 0.035
positive regulation of multicellular organism growth GO:0040018 352 0.035
nucleic acid metabolic process GO:0090304 299 0.034
positive regulation of developmental growth GO:0048639 354 0.034
cellular localization GO:0051641 360 0.034
protein complex subunit organization GO:0071822 280 0.033
regulation of protein metabolic process GO:0051246 81 0.033
protein localization GO:0008104 205 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.032
regulation of cell communication GO:0010646 176 0.032
establishment of localization in cell GO:0051649 318 0.031
membrane organization GO:0061024 135 0.031
regulation of cellular metabolic process GO:0031323 305 0.031
head development GO:0060322 1 0.030
cellular protein modification process GO:0006464 207 0.030
regulation of apoptotic process GO:0042981 36 0.029
organelle localization GO:0051640 127 0.029
protein localization to basolateral plasma membrane GO:1903361 7 0.029
generation of neurons GO:0048699 235 0.029
rho protein signal transduction GO:0007266 2 0.029
vulval development GO:0040025 333 0.029
oxoacid metabolic process GO:0043436 47 0.028
macromolecular complex assembly GO:0065003 193 0.028
signaling GO:0023052 401 0.028
Mouse
carboxylic acid metabolic process GO:0019752 34 0.027
response to endoplasmic reticulum stress GO:0034976 71 0.027
positive regulation of developmental process GO:0051094 408 0.027
heterocycle catabolic process GO:0046700 119 0.027
regulation of gene expression GO:0010468 366 0.026
cell motility GO:0048870 313 0.026
phosphorus metabolic process GO:0006793 232 0.026
negative regulation of developmental process GO:0051093 227 0.026
regulation of cell death GO:0010941 65 0.026
negative regulation of macromolecule metabolic process GO:0010605 229 0.025
negative regulation of gene expression GO:0010629 217 0.025
signal transduction GO:0007165 317 0.025
Mouse
regulation of response to stimulus GO:0048583 243 0.025
single organism organelle organization GO:1902589 501 0.025
innate immune response GO:0045087 190 0.025
localization of cell GO:0051674 313 0.024
epithelial tube morphogenesis GO:0060562 1 0.024
phosphate containing compound metabolic process GO:0006796 232 0.024
cellular component biogenesis GO:0044085 297 0.023
regulation of cell differentiation GO:0045595 81 0.023
regulation of primary metabolic process GO:0080090 292 0.023
macromolecular complex subunit organization GO:0043933 320 0.022
phagocytosis engulfment GO:0006911 98 0.022
cellular component movement GO:0006928 388 0.022
regulation of vulval development GO:0040028 248 0.022
negative regulation of multicellular organismal process GO:0051241 236 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.021
macromolecule biosynthetic process GO:0009059 250 0.021
organic substance transport GO:0071702 113 0.021
cellular macromolecule biosynthetic process GO:0034645 247 0.021
epithelium development GO:0060429 68 0.021
cell part morphogenesis GO:0032990 152 0.021
Mouse
skeletal muscle organ development GO:0060538 3 0.020
muscle tissue development GO:0060537 1 0.020
actin filament based process GO:0030029 191 0.020
secretion by cell GO:0032940 138 0.020
catabolic process GO:0009056 318 0.020
regulation of signaling GO:0023051 172 0.020
system process GO:0003008 136 0.020
regulation of localization GO:0032879 194 0.020
tissue development GO:0009888 112 0.020
regulation of anatomical structure size GO:0090066 46 0.020
oocyte development GO:0048599 44 0.020
immune response GO:0006955 192 0.019
cell cell signaling GO:0007267 118 0.019
lipid metabolic process GO:0006629 77 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
negative regulation of post embryonic development GO:0048581 208 0.019
negative regulation of vulval development GO:0040027 206 0.019
regulation of signal transduction GO:0009966 135 0.018
single organism biosynthetic process GO:0044711 91 0.018
cell proliferation GO:0008283 116 0.018
organic cyclic compound biosynthetic process GO:1901362 195 0.018
regulation of macromolecule biosynthetic process GO:0010556 189 0.018
nervous system development GO:0007399 253 0.018
response to bacterium GO:0009617 86 0.017
regulation of cell cycle GO:0051726 194 0.017
cellular amino acid metabolic process GO:0006520 15 0.017
neurogenesis GO:0022008 236 0.017
cell projection morphogenesis GO:0048858 148 0.017
Mouse
embryonic body morphogenesis GO:0010172 49 0.017
rna interference GO:0016246 137 0.017
response to organic substance GO:0010033 131 0.017
cellular amine metabolic process GO:0044106 15 0.017
aromatic compound biosynthetic process GO:0019438 192 0.017
gene silencing by rna GO:0031047 143 0.017
negative regulation of response to stimulus GO:0048585 73 0.017
amine metabolic process GO:0009308 15 0.017
regulation of cellular component organization GO:0051128 248 0.017
rna localization GO:0006403 3 0.017
response to external biotic stimulus GO:0043207 101 0.016
cellular response to topologically incorrect protein GO:0035967 76 0.016
positive regulation of cellular process GO:0048522 332 0.016
adult behavior GO:0030534 3 0.016
regulation of programmed cell death GO:0043067 50 0.016
intracellular signal transduction GO:0035556 96 0.016
macromolecule catabolic process GO:0009057 202 0.016
posttranscriptional gene silencing GO:0016441 143 0.016
gene silencing GO:0016458 143 0.016
cell migration GO:0016477 306 0.016
response to wounding GO:0009611 4 0.016
protein complex biogenesis GO:0070271 186 0.016
protein complex assembly GO:0006461 186 0.016
cell morphogenesis involved in differentiation GO:0000904 112 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
response to temperature stimulus GO:0009266 66 0.015
myosin filament organization GO:0031033 138 0.015
positive regulation of cellular metabolic process GO:0031325 178 0.015
cytoskeleton organization GO:0007010 339 0.015
regulation of epithelial cell proliferation GO:0050678 1 0.015
cellular ketone metabolic process GO:0042180 14 0.015
neuromuscular junction development GO:0007528 2 0.015
regulation of cell proliferation GO:0042127 105 0.015
muscle cell differentiation GO:0042692 171 0.015
regulation of cellular biosynthetic process GO:0031326 189 0.015
response to oxygen containing compound GO:1901700 44 0.015
neuron projection development GO:0031175 187 0.015
transcription from rna polymerase ii promoter GO:0006366 149 0.015
ras protein signal transduction GO:0007265 31 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
regulation of nitrogen compound metabolic process GO:0051171 222 0.014
small gtpase mediated signal transduction GO:0007264 32 0.014
rna metabolic process GO:0016070 228 0.014
positive regulation of metabolic process GO:0009893 187 0.014
single organism behavior GO:0044708 83 0.014
synaptic transmission GO:0007268 106 0.014
protein catabolic process GO:0030163 162 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.014
neuron development GO:0048666 199 0.014
embryonic morphogenesis GO:0048598 152 0.014
regulation of cell division GO:0051302 142 0.014
actin cytoskeleton organization GO:0030036 184 0.014
cellular macromolecule catabolic process GO:0044265 73 0.013
regulation of neurogenesis GO:0050767 40 0.013
response to topologically incorrect protein GO:0035966 82 0.013
myofibril assembly GO:0030239 154 0.013
cellular component morphogenesis GO:0032989 318 0.013
Mouse
response to acid chemical GO:0001101 4 0.013
response to other organism GO:0051707 101 0.013
muscle structure development GO:0061061 191 0.013
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
single organism catabolic process GO:0044712 129 0.013
negative regulation of neurogenesis GO:0050768 4 0.013
regulation of transcription dna templated GO:0006355 164 0.013
ribonucleoside triphosphate catabolic process GO:0009203 72 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
meiotic cell cycle process GO:1903046 170 0.013
cellular catabolic process GO:0044248 199 0.013
response to abiotic stimulus GO:0009628 152 0.013
Mouse
sphingolipid metabolic process GO:0006665 2 0.013
membrane invagination GO:0010324 98 0.013
secretion GO:0046903 147 0.013
glycosyl compound metabolic process GO:1901657 100 0.013
ribosome biogenesis GO:0042254 4 0.013
protein phosphorylation GO:0006468 85 0.013
regulation of gene expression epigenetic GO:0040029 163 0.012
phosphorylation GO:0016310 116 0.012
cell surface receptor signaling pathway GO:0007166 149 0.012
Mouse
pigmentation GO:0043473 2 0.012
nucleic acid templated transcription GO:0097659 169 0.012
regulation of vesicle mediated transport GO:0060627 27 0.012
myosin filament assembly GO:0031034 138 0.012
striated muscle cell development GO:0055002 157 0.012
nucleoside phosphate catabolic process GO:1901292 77 0.012
carbohydrate derivative catabolic process GO:1901136 82 0.012
organic cyclic compound catabolic process GO:1901361 119 0.012
cellular protein complex assembly GO:0043623 178 0.012
negative regulation of signal transduction GO:0009968 60 0.012
ribonucleoside catabolic process GO:0042454 77 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.012
organelle assembly GO:0070925 214 0.012
organophosphate catabolic process GO:0046434 81 0.012
oocyte differentiation GO:0009994 45 0.012
cellular macromolecular complex assembly GO:0034622 184 0.012
regulation of mitotic cell cycle GO:0007346 76 0.012
cell substrate adhesion GO:0031589 1 0.012
regulation of organelle organization GO:0033043 164 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
dendrite development GO:0016358 42 0.012
nucleoside phosphate metabolic process GO:0006753 108 0.011
heterocycle biosynthetic process GO:0018130 187 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
golgi vesicle transport GO:0048193 3 0.011
muscle cell development GO:0055001 158 0.011
regulation of nucleic acid templated transcription GO:1903506 165 0.011
neuron differentiation GO:0030182 217 0.011
cellular component assembly GO:0022607 293 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
regulation of nervous system development GO:0051960 41 0.011
positive regulation of macromolecule metabolic process GO:0010604 149 0.011
regulation of response to wounding GO:1903034 1 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
organonitrogen compound catabolic process GO:1901565 90 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
rna biosynthetic process GO:0032774 169 0.011
cellular response to organic substance GO:0071310 119 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.011
glutathione metabolic process GO:0006749 2 0.011
synaptic vesicle endocytosis GO:0048488 3 0.011
response to inorganic substance GO:0010035 50 0.011
regulation of neuron differentiation GO:0045664 40 0.011
cell cycle g1 s phase transition GO:0044843 2 0.011
membrane budding GO:0006900 1 0.011
engulfment of apoptotic cell GO:0043652 94 0.011
hatching GO:0035188 48 0.010
nucleotide metabolic process GO:0009117 108 0.010
response to unfolded protein GO:0006986 71 0.010
regulation of transport GO:0051049 91 0.010
cellular response to stress GO:0033554 162 0.010
axonogenesis GO:0007409 102 0.010
oocyte construction GO:0007308 2 0.010
epithelial cell proliferation GO:0050673 1 0.010
mitotic nuclear division GO:0007067 89 0.010
organism emergence from protective structure GO:0071684 48 0.010
protein oligomerization GO:0051259 4 0.010
cellular nitrogen compound catabolic process GO:0044270 119 0.010
regulation of locomotion GO:0040012 161 0.010
negative regulation of cell communication GO:0010648 61 0.010
negative regulation of signaling GO:0023057 61 0.010
apoptotic cell clearance GO:0043277 111 0.010

rop-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.016