Caenorhabditis elegans

146 known processes

unc-5 (CELE_B0273.4)

Protein UNC-5

unc-5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.355
tube development GO:0035295 126 0.354
multicellular organism reproduction GO:0032504 819 0.281
anterior posterior axon guidance GO:0033564 5 0.245
Mouse
dorsal ventral axon guidance GO:0033563 19 0.232
multicellular organismal reproductive process GO:0048609 815 0.227
multi organism behavior GO:0051705 389 0.218
regulation of developmental process GO:0050793 684 0.214
regulation of locomotion GO:0040012 161 0.206
multicellular organismal reproductive behavior GO:0033057 384 0.197
regulation of multicellular organismal process GO:0051239 726 0.195
cell morphogenesis GO:0000902 163 0.195
reproductive behavior GO:0019098 387 0.189
oviposition GO:0018991 364 0.171
multi organism reproductive process GO:0044703 867 0.166
neuron differentiation GO:0030182 217 0.163
neuron projection guidance GO:0097485 82 0.161
developmental growth GO:0048589 412 0.153
organ development GO:0048513 1102 0.150
negative regulation of developmental process GO:0051093 227 0.142
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 2992 0.142
chemotaxis GO:0006935 120 0.136
single organism signaling GO:0044700 401 0.134
Human Mouse Rat
anatomical structure formation involved in morphogenesis GO:0048646 250 0.132
locomotion GO:0040011 1634 0.126
post embryonic organ development GO:0048569 336 0.113
multi organism reproductive behavior GO:0044705 387 0.111
embryo development GO:0009790 3052 0.111
cell cycle GO:0007049 526 0.110
taxis GO:0042330 128 0.108
regulation of developmental growth GO:0048638 389 0.108
single organism localization GO:1902578 518 0.106
single organism transport GO:0044765 447 0.103
aging GO:0007568 812 0.101
establishment of vesicle localization GO:0051650 23 0.100
head development GO:0060322 1 0.098
Mouse
vesicle mediated transport GO:0016192 852 0.097
microtubule based process GO:0007017 182 0.096
epithelial tube morphogenesis GO:0060562 1 0.096
Zebrafish
positive regulation of jnk cascade GO:0046330 3 0.095
positive regulation of multicellular organismal process GO:0051240 417 0.095
establishment of localization GO:0051234 1171 0.094
neuron projection morphogenesis GO:0048812 114 0.093
multi multicellular organism process GO:0044706 390 0.091
negative regulation of biological process GO:0048519 567 0.090
Human Zebrafish
neuron projection development GO:0031175 187 0.089
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.089
axonogenesis GO:0007409 102 0.089
wnt signaling pathway GO:0016055 27 0.087
positive regulation of cellular process GO:0048522 332 0.085
behavior GO:0007610 527 0.085
localization of cell GO:0051674 313 0.078
establishment of localization in cell GO:0051649 318 0.077
generation of neurons GO:0048699 235 0.077
cell projection morphogenesis GO:0048858 148 0.076
canonical wnt signaling pathway GO:0060070 3 0.076
regulation of growth GO:0040008 409 0.074
developmental process involved in reproduction GO:0003006 1165 0.073
negative regulation of cellular process GO:0048523 239 0.071
Human
gonad development GO:0008406 840 0.071
embryonic morphogenesis GO:0048598 152 0.070
regulation of response to stimulus GO:0048583 243 0.069
Human
cell morphogenesis involved in differentiation GO:0000904 112 0.068
germ cell development GO:0007281 351 0.068
cellular protein metabolic process GO:0044267 279 0.065
apoptotic process GO:0006915 478 0.064
Human Mouse
determination of adult lifespan GO:0008340 812 0.062
regulation of multicellular organism growth GO:0040014 373 0.062
multicellular organismal aging GO:0010259 812 0.062
epidermis morphogenesis GO:0048730 7 0.062
positive regulation of developmental growth GO:0048639 354 0.062
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.061
neuron projection extension GO:1990138 37 0.061
transport GO:0006810 1093 0.060
establishment of organelle localization GO:0051656 123 0.059
reproductive structure development GO:0048608 850 0.059
regulation of cellular component movement GO:0051270 62 0.058
Mouse
growth GO:0040007 562 0.058
response to external stimulus GO:0009605 289 0.058
cell part morphogenesis GO:0032990 152 0.058
sex differentiation GO:0007548 909 0.057
cellular component movement GO:0006928 388 0.057
positive regulation of multicellular organism growth GO:0040018 352 0.057
positive regulation of stress activated mapk cascade GO:0032874 3 0.057
regulation of cell cycle process GO:0010564 145 0.055
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.055
sexual reproduction GO:0019953 546 0.055
cellular localization GO:0051641 360 0.054
organelle organization GO:0006996 783 0.053
nucleotide metabolic process GO:0009117 108 0.053
muscle tissue development GO:0060537 1 0.053
neuron development GO:0048666 199 0.053
axon development GO:0061564 163 0.052
regulation of canonical wnt signaling pathway GO:0060828 1 0.050
regulation of cell cycle GO:0051726 194 0.050
regulation of cellular component size GO:0032535 40 0.050
lipid storage GO:0019915 565 0.049
tissue morphogenesis GO:0048729 65 0.049
endocytosis GO:0006897 819 0.049
phosphorus metabolic process GO:0006793 232 0.048
positive regulation of developmental process GO:0051094 408 0.048
spindle organization GO:0007051 92 0.048
tissue development GO:0009888 112 0.047
cellular component morphogenesis GO:0032989 318 0.047
gamete generation GO:0007276 461 0.047
negative regulation of multicellular organismal process GO:0051241 236 0.047
Zebrafish
regulation of cell migration GO:0030334 55 0.046
Mouse
female gamete generation GO:0007292 254 0.045
positive regulation of neuron projection development GO:0010976 4 0.044
signal transduction GO:0007165 317 0.044
Human Mouse Rat
epithelium development GO:0060429 68 0.044
Zebrafish
body morphogenesis GO:0010171 620 0.043
regulation of biological quality GO:0065008 741 0.043
regulation of wnt signaling pathway GO:0030111 9 0.042
maintenance of location GO:0051235 580 0.042
cellular protein modification process GO:0006464 207 0.042
lipid localization GO:0010876 573 0.042
oogenesis GO:0048477 229 0.041
signaling GO:0023052 401 0.041
Human Mouse Rat
gene expression GO:0010467 412 0.041
phosphate containing compound metabolic process GO:0006796 232 0.041
filopodium assembly GO:0046847 2 0.041
positive regulation of neuron differentiation GO:0045666 4 0.040
cell death GO:0008219 547 0.040
Human Mouse
nucleobase containing compound metabolic process GO:0006139 406 0.039
multicellular organism growth GO:0035264 385 0.039
single organism reproductive process GO:0044702 1196 0.039
digestive system development GO:0055123 122 0.038
axon extension GO:0048675 37 0.038
negative regulation of wnt signaling pathway GO:0030178 6 0.038
protein complex subunit organization GO:0071822 280 0.038
small molecule metabolic process GO:0044281 186 0.038
regulation of primary metabolic process GO:0080090 292 0.037
macromolecule biosynthetic process GO:0009059 250 0.037
synaptic vesicle localization GO:0097479 22 0.036
actin filament based process GO:0030029 191 0.036
macromolecule localization GO:0033036 771 0.036
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.035
regulation of neuron differentiation GO:0045664 40 0.035
regulation of macromolecule metabolic process GO:0060255 421 0.035
innate immune response GO:0045087 190 0.035
organic substance biosynthetic process GO:1901576 323 0.034
vulval development GO:0040025 333 0.034
tube morphogenesis GO:0035239 79 0.034
regulation of cellular metabolic process GO:0031323 305 0.034
cell projection organization GO:0030030 231 0.034
regulation of gene expression GO:0010468 366 0.034
cell cycle process GO:0022402 482 0.034
regulation of vulval development GO:0040028 248 0.033
receptor mediated endocytosis GO:0006898 715 0.033
positive regulation of growth GO:0045927 369 0.033
cellular component assembly GO:0022607 293 0.033
positive regulation of neurogenesis GO:0050769 4 0.033
organelle localization GO:0051640 127 0.033
nervous system development GO:0007399 253 0.032
skin development GO:0043588 24 0.032
cell type specific apoptotic process GO:0097285 4 0.032
Human
apical junction assembly GO:0043297 1 0.032
positive regulation of signaling GO:0023056 66 0.032
Human
organonitrogen compound metabolic process GO:1901564 151 0.031
positive regulation of metabolic process GO:0009893 187 0.031
positive regulation of response to stimulus GO:0048584 55 0.031
Human
organic substance catabolic process GO:1901575 294 0.031
developmental cell growth GO:0048588 39 0.030
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.030
organelle assembly GO:0070925 214 0.030
axon guidance GO:0007411 82 0.029
cellular nitrogen compound biosynthetic process GO:0044271 192 0.029
skin morphogenesis GO:0043589 7 0.029
regulation of multicellular organismal development GO:2000026 317 0.029
rna metabolic process GO:0016070 228 0.029
cell motility GO:0048870 313 0.029
intracellular signal transduction GO:0035556 96 0.028
Human
development of primary sexual characteristics GO:0045137 840 0.028
ribonucleotide metabolic process GO:0009259 99 0.028
positive regulation of cellular metabolic process GO:0031325 178 0.028
negative regulation of signaling GO:0023057 61 0.028
Human
stress activated mapk cascade GO:0051403 10 0.028
neurogenesis GO:0022008 236 0.028
mesodermal cell migration GO:0008078 9 0.028
cell adhesion GO:0007155 21 0.027
macromolecular complex subunit organization GO:0043933 320 0.027
protein localization GO:0008104 205 0.027
regulation of mitotic cell cycle GO:0007346 76 0.027
embryonic body morphogenesis GO:0010172 49 0.027
response to chemical GO:0042221 356 0.027
epidermis development GO:0008544 24 0.026
negative chemotaxis GO:0050919 1 0.026
establishment or maintenance of cell polarity GO:0007163 63 0.026
immune response GO:0006955 192 0.026
muscle attachment GO:0016203 3 0.026
regulation of cell motility GO:2000145 57 0.026
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.025
striated muscle cell differentiation GO:0051146 158 0.025
regulation of stem cell differentiation GO:2000736 1 0.025
regulation of localization GO:0032879 194 0.025
Mouse
cell maturation GO:0048469 26 0.025
secretion by cell GO:0032940 138 0.024
extracellular matrix organization GO:0030198 6 0.024
regulation of catalytic activity GO:0050790 78 0.024
programmed cell death GO:0012501 500 0.024
Human Mouse
engulfment of apoptotic cell GO:0043652 94 0.024
regulation of phosphorus metabolic process GO:0051174 81 0.023
regulation of filopodium assembly GO:0051489 2 0.023
regulation of nematode larval development GO:0061062 260 0.023
biosynthetic process GO:0009058 323 0.023
single organism organelle organization GO:1902589 501 0.022
response to wounding GO:0009611 4 0.022
reproductive system development GO:0061458 850 0.022
regulation of metabolic process GO:0019222 478 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.022
cell division GO:0051301 262 0.022
muscle cell differentiation GO:0042692 171 0.021
positive regulation of rna metabolic process GO:0051254 103 0.021
cellular nitrogen compound catabolic process GO:0044270 119 0.021
mitotic cell cycle process GO:1903047 194 0.021
positive regulation of gene expression GO:0010628 112 0.021
short term memory GO:0007614 2 0.021
protein metabolic process GO:0019538 422 0.021
negative regulation of axonogenesis GO:0050771 2 0.021
muscle structure development GO:0061061 191 0.021
cell recognition GO:0008037 85 0.021
regulation of molecular function GO:0065009 89 0.021
sensory organ morphogenesis GO:0090596 2 0.021
regulation of cell division GO:0051302 142 0.021
cellular biosynthetic process GO:0044249 315 0.020
regulation of nitrogen compound metabolic process GO:0051171 222 0.020
cellular macromolecule biosynthetic process GO:0034645 247 0.020
biological adhesion GO:0022610 21 0.020
nucleobase containing small molecule metabolic process GO:0055086 115 0.019
muscle cell development GO:0055001 158 0.019
microtubule based movement GO:0007018 33 0.019
axon cargo transport GO:0008088 7 0.019
cell migration GO:0016477 306 0.019
positive regulation of cell projection organization GO:0031346 4 0.019
synaptic target recognition GO:0008039 3 0.018
organic substance transport GO:0071702 113 0.018
regulation of epithelial cell proliferation GO:0050678 1 0.018
positive regulation of molecular function GO:0044093 61 0.018
cell matrix adhesion GO:0007160 1 0.018
system process GO:0003008 136 0.018
skeletal muscle organ development GO:0060538 3 0.018
specification of axis polarity GO:0065001 13 0.017
muscle organ morphogenesis GO:0048644 4 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
negative regulation of axon extension GO:0030517 2 0.017
phagocytosis engulfment GO:0006911 98 0.017
protein modification process GO:0036211 207 0.017
negative regulation of vulval development GO:0040027 206 0.017
jnk cascade GO:0007254 8 0.017
synaptic vesicle transport GO:0048489 21 0.017
regulation of axonogenesis GO:0050770 24 0.017
posttranscriptional regulation of gene expression GO:0010608 166 0.017
cell cell signaling GO:0007267 118 0.017
positive regulation of epithelial cell proliferation GO:0050679 1 0.016
striated muscle cell development GO:0055002 157 0.016
neuron recognition GO:0008038 83 0.016
memory GO:0007613 3 0.016
actin cytoskeleton organization GO:0030036 184 0.016
negative regulation of neurogenesis GO:0050768 4 0.016
positive regulation of cell differentiation GO:0045597 8 0.016
cellular component biogenesis GO:0044085 297 0.016
regulation of anatomical structure morphogenesis GO:0022603 51 0.016
nucleic acid metabolic process GO:0090304 299 0.016
regulation of transcription dna templated GO:0006355 164 0.016
heterocycle catabolic process GO:0046700 119 0.016
mating GO:0007618 34 0.015
regulation of phosphate metabolic process GO:0019220 81 0.015
neuromuscular junction development GO:0007528 2 0.015
genitalia development GO:0048806 741 0.015
nucleobase containing compound catabolic process GO:0034655 114 0.015
vesicle localization GO:0051648 24 0.015
negative regulation of gene expression GO:0010629 217 0.015
regulation of cell proliferation GO:0042127 105 0.015
regulation of cell communication GO:0010646 176 0.015
Human
nucleoside phosphate metabolic process GO:0006753 108 0.015
regulation of cell morphogenesis GO:0022604 40 0.015
nucleotide sugar metabolic process GO:0009225 6 0.015
negative regulation of macromolecule metabolic process GO:0010605 229 0.015
positive regulation of cell migration GO:0030335 3 0.015
regulation of extent of cell growth GO:0061387 20 0.014
cell substrate adhesion GO:0031589 1 0.014
digestive tract development GO:0048565 122 0.014
regulation of cell projection organization GO:0031344 38 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.014
response to external biotic stimulus GO:0043207 101 0.014
regulation of cell development GO:0060284 49 0.014
macromolecule modification GO:0043412 218 0.014
regulation of jun kinase activity GO:0043506 3 0.013
axon extension involved in axon guidance GO:0048846 13 0.013
cell development GO:0048468 696 0.013
negative regulation of organ growth GO:0046621 1 0.013
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.013
regulation of post embryonic development GO:0048580 260 0.013
regulation of signal transduction GO:0009966 135 0.013
Human
lamellipodium organization GO:0097581 2 0.013
stress activated protein kinase signaling cascade GO:0031098 10 0.013
pattern specification process GO:0007389 59 0.013
Zebrafish Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.013
polarity specification of proximal distal axis GO:0010085 6 0.013
dna metabolic process GO:0006259 74 0.013
regulation of intracellular signal transduction GO:1902531 77 0.012
Human
positive regulation of cell cycle GO:0045787 55 0.012
negative regulation of locomotion GO:0040013 21 0.012
regeneration GO:0031099 4 0.012
negative regulation of response to stimulus GO:0048585 73 0.012
Human
regulation of macromolecule biosynthetic process GO:0010556 189 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.012
regulation of rna biosynthetic process GO:2001141 165 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
regulation of rna metabolic process GO:0051252 173 0.012
dendrite development GO:0016358 42 0.012
regulation of actin filament based process GO:0032970 22 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.012
catabolic process GO:0009056 318 0.012
muscle fiber development GO:0048747 2 0.012
positive regulation of locomotion GO:0040017 42 0.012
apoptotic cell clearance GO:0043277 111 0.012
phagocytosis GO:0006909 115 0.012
carbohydrate derivative metabolic process GO:1901135 141 0.012
regulation of cell differentiation GO:0045595 81 0.012
single organism intracellular transport GO:1902582 70 0.012
regulation of nervous system development GO:0051960 41 0.012
ovulation GO:0030728 33 0.012
regulation of biosynthetic process GO:0009889 189 0.012
cytoskeleton organization GO:0007010 339 0.011
ribonucleoside metabolic process GO:0009119 98 0.011
purine containing compound metabolic process GO:0072521 95 0.011
hermaphrodite genitalia development GO:0040035 734 0.011
cellular response to organic substance GO:0071310 119 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.011
membrane invagination GO:0010324 98 0.011
microtubule based transport GO:0010970 19 0.011
regulation of organelle organization GO:0033043 164 0.011
myofibril assembly GO:0030239 154 0.011
cellular response to stress GO:0033554 162 0.011
regulation of gene expression epigenetic GO:0040029 163 0.011
ribonucleotide catabolic process GO:0009261 75 0.011
positive regulation of phosphate metabolic process GO:0045937 56 0.011
cell cell junction assembly GO:0007043 2 0.011
cellular protein localization GO:0034613 75 0.011
regulation of cytoskeleton organization GO:0051493 41 0.011
actin cytoskeleton reorganization GO:0031532 4 0.011
lamellipodium assembly GO:0030032 2 0.010
aromatic compound biosynthetic process GO:0019438 192 0.010
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.010
regulation of anatomical structure size GO:0090066 46 0.010
negative regulation of neuron differentiation GO:0045665 4 0.010
phosphorylation GO:0016310 116 0.010
synaptic transmission GO:0007268 106 0.010
organic cyclic compound catabolic process GO:1901361 119 0.010
regulation of bmp signaling pathway GO:0030510 3 0.010
actin filament organization GO:0007015 21 0.010
motor neuron axon guidance GO:0008045 13 0.010
establishment of cell polarity GO:0030010 46 0.010
establishment of spindle localization GO:0051293 51 0.010

unc-5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org