Caenorhabditis elegans

13 known processes

rskn-2 (CELE_C54G4.1)

Protein RSKN-2

rskn-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic cyclic compound biosynthetic process GO:1901362 195 0.487
Human Mouse Fly
organelle organization GO:0006996 783 0.413
Human Worm Fly
cation transport GO:0006812 78 0.380
multicellular organism reproduction GO:0032504 819 0.378
Fly
regulation of transcription dna templated GO:0006355 164 0.377
Human Mouse Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.356
Human
multicellular organismal aging GO:0010259 812 0.329
Worm
regulation of cellular biosynthetic process GO:0031326 189 0.282
Human Mouse Fly
embryo development GO:0009790 3052 0.271
single organism signaling GO:0044700 401 0.270
Human Mouse
single organism organelle organization GO:1902589 501 0.268
Human Fly
macromolecule localization GO:0033036 771 0.261
locomotion GO:0040011 1634 0.257
germ cell development GO:0007281 351 0.241
Fly
cellular biosynthetic process GO:0044249 315 0.238
Human Mouse Worm Fly
organic substance biosynthetic process GO:1901576 323 0.234
Human Mouse Worm Fly
gene expression GO:0010467 412 0.225
Human Mouse Worm Fly
nucleobase containing compound metabolic process GO:0006139 406 0.221
Human Mouse Fly
cell cycle GO:0007049 526 0.219
Fly
cell development GO:0048468 696 0.215
Fly
regulation of rna metabolic process GO:0051252 173 0.215
Human Mouse Fly
regulation of biosynthetic process GO:0009889 189 0.206
Human Mouse Fly
cellular component assembly GO:0022607 293 0.200
Worm
oogenesis GO:0048477 229 0.199
Fly
aromatic compound biosynthetic process GO:0019438 192 0.198
Human Mouse Fly
single organism transport GO:0044765 447 0.189
signaling GO:0023052 401 0.187
Human Mouse
multi organism reproductive process GO:0044703 867 0.187
Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.176
Human Mouse Fly
post embryonic development GO:0009791 2152 0.175
regulation of biological quality GO:0065008 741 0.175
Fly
biosynthetic process GO:0009058 323 0.172
Human Mouse Worm Fly
developmental process involved in reproduction GO:0003006 1165 0.172
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.167
Human Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 189 0.164
Human Mouse Fly
regulation of primary metabolic process GO:0080090 292 0.163
Human Mouse Fly
g protein coupled receptor signaling pathway GO:0007186 46 0.160
negative regulation of gene expression GO:0010629 217 0.159
Human Fly
nucleic acid metabolic process GO:0090304 299 0.157
Human Mouse Fly
rna metabolic process GO:0016070 228 0.152
Human Mouse Fly
positive regulation of multicellular organismal process GO:0051240 417 0.151
nucleic acid templated transcription GO:0097659 169 0.148
Human Mouse Fly
rna biosynthetic process GO:0032774 169 0.138
Human Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 149 0.137
Human
heterocycle biosynthetic process GO:0018130 187 0.136
Human Mouse Fly
cell cell signaling GO:0007267 118 0.136
monocarboxylic acid metabolic process GO:0032787 22 0.135
cytoskeleton organization GO:0007010 339 0.135
body morphogenesis GO:0010171 620 0.134
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.133
Human Fly
response to wounding GO:0009611 4 0.129
cellular macromolecule biosynthetic process GO:0034645 247 0.129
Human Mouse Worm Fly
regulation of cellular component organization GO:0051128 248 0.128
Human Worm
determination of adult lifespan GO:0008340 812 0.126
Worm
organelle assembly GO:0070925 214 0.125
Worm
regulation of signaling GO:0023051 172 0.124
cellular component biogenesis GO:0044085 297 0.124
Worm
transcription dna templated GO:0006351 168 0.124
Human Mouse Fly
aging GO:0007568 812 0.123
Worm
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.122
female gamete generation GO:0007292 254 0.121
Fly
negative regulation of cellular biosynthetic process GO:0031327 65 0.120
Human Fly
regulation of macromolecule metabolic process GO:0060255 421 0.120
Human Mouse Fly
protein modification process GO:0036211 207 0.119
Human Mouse Fly
oviposition GO:0018991 364 0.112
macromolecular complex assembly GO:0065003 193 0.106
sex differentiation GO:0007548 909 0.105
response to chemical GO:0042221 356 0.103
Human
positive regulation of multicellular organism growth GO:0040018 352 0.101
regulation of signal transduction GO:0009966 135 0.100
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.100
Human Fly
organ development GO:0048513 1102 0.098
lipid localization GO:0010876 573 0.093
cellular response to organic substance GO:0071310 119 0.092
Human
regulation of gene expression GO:0010468 366 0.090
Human Mouse Fly
multicellular organismal reproductive process GO:0048609 815 0.090
Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.090
Human Mouse Fly
maintenance of location GO:0051235 580 0.089
transport GO:0006810 1093 0.089
embryo development ending in birth or egg hatching GO:0009792 2992 0.088
organic acid metabolic process GO:0006082 47 0.088
positive regulation of growth GO:0045927 369 0.087
regulation of nucleic acid templated transcription GO:1903506 165 0.086
Human Mouse Fly
positive regulation of biosynthetic process GO:0009891 109 0.086
Human Fly
lipid storage GO:0019915 565 0.084
regulation of multicellular organism growth GO:0040014 373 0.082
cell division GO:0051301 262 0.082
negative regulation of cellular process GO:0048523 239 0.081
Human Fly
positive regulation of macromolecule metabolic process GO:0010604 149 0.080
Human Fly
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.079
Fly
cellular response to abiotic stimulus GO:0071214 4 0.078
macromolecular complex subunit organization GO:0043933 320 0.078
Human Fly
response to peptide hormone GO:0043434 14 0.077
nervous system development GO:0007399 253 0.077
neuron development GO:0048666 199 0.077
ion transport GO:0006811 113 0.075
phosphate containing compound metabolic process GO:0006796 232 0.074
Human Mouse Fly
single organism localization GO:1902578 518 0.072
regulation of rna biosynthetic process GO:2001141 165 0.069
Human Mouse Fly
negative regulation of biosynthetic process GO:0009890 65 0.069
Human Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.068
Human Fly
neuron projection development GO:0031175 187 0.067
multicellular organism growth GO:0035264 385 0.066
organonitrogen compound metabolic process GO:1901564 151 0.063
negative regulation of metabolic process GO:0009892 240 0.062
Human Fly
positive regulation of developmental growth GO:0048639 354 0.061
multi organism behavior GO:0051705 389 0.061
single organism behavior GO:0044708 83 0.061
protein complex subunit organization GO:0071822 280 0.061
single organism biosynthetic process GO:0044711 91 0.060
neurogenesis GO:0022008 236 0.060
organelle fission GO:0048285 363 0.060
Fly
negative regulation of biological process GO:0048519 567 0.059
Human Fly
generation of neurons GO:0048699 235 0.059
single organism reproductive process GO:0044702 1196 0.059
Fly
positive regulation of transcription dna templated GO:0045893 102 0.058
Human Fly
macromolecule modification GO:0043412 218 0.058
Human Mouse Fly
regulation of developmental growth GO:0048638 389 0.057
regulation of multicellular organismal process GO:0051239 726 0.057
cell projection organization GO:0030030 231 0.055
growth GO:0040007 562 0.053
regulation of metabolic process GO:0019222 478 0.053
Human Mouse Worm Fly
actin cytoskeleton organization GO:0030036 184 0.053
small molecule metabolic process GO:0044281 186 0.052
oxoacid metabolic process GO:0043436 47 0.052
gamete generation GO:0007276 461 0.051
Fly
dauer larval development GO:0040024 92 0.050
carboxylic acid metabolic process GO:0019752 34 0.050
negative regulation of rna metabolic process GO:0051253 53 0.050
Human Fly
establishment of localization GO:0051234 1171 0.050
macromolecule biosynthetic process GO:0009059 250 0.049
Human Mouse Worm Fly
system process GO:0003008 136 0.049
response to abiotic stimulus GO:0009628 152 0.049
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.046
Human Mouse Fly
protein complex assembly GO:0006461 186 0.045
organic substance transport GO:0071702 113 0.045
regulation of behavior GO:0050795 97 0.045
molting cycle GO:0042303 281 0.045
apoptotic process GO:0006915 478 0.044
death GO:0016265 547 0.043
regulation of cellular metabolic process GO:0031323 305 0.043
Human Mouse Worm Fly
regulation of neurotransmitter levels GO:0001505 36 0.043
regulation of secretion GO:0051046 29 0.043
regulation of nitrogen compound metabolic process GO:0051171 222 0.042
Human Mouse Fly
phosphorus metabolic process GO:0006793 232 0.042
Human Mouse Fly
reproductive behavior GO:0019098 387 0.042
programmed cell death GO:0012501 500 0.042
multi multicellular organism process GO:0044706 390 0.041
nitrogen compound transport GO:0071705 49 0.040
phosphorylation GO:0016310 116 0.040
Human Mouse Fly
cell cycle process GO:0022402 482 0.040
Fly
cellular localization GO:0051641 360 0.040
positive regulation of cellular metabolic process GO:0031325 178 0.040
Human Worm Fly
sexual reproduction GO:0019953 546 0.039
Fly
cell surface receptor signaling pathway GO:0007166 149 0.039
Human
actin filament based process GO:0030029 191 0.038
guanosine containing compound metabolic process GO:1901068 49 0.038
multi organism reproductive behavior GO:0044705 387 0.038
behavior GO:0007610 527 0.038
meiotic nuclear division GO:0007126 300 0.037
Fly
regulation of organelle organization GO:0033043 164 0.037
Human Worm
cellular macromolecular complex assembly GO:0034622 184 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.036
Human Fly
cell junction organization GO:0034330 18 0.036
localization of cell GO:0051674 313 0.036
cellular amino acid metabolic process GO:0006520 15 0.036
vesicle mediated transport GO:0016192 852 0.035
signal release GO:0023061 28 0.035
multicellular organismal reproductive behavior GO:0033057 384 0.034
regulation of programmed cell death GO:0043067 50 0.034
response to organic substance GO:0010033 131 0.034
Human
membrane organization GO:0061024 135 0.034
protein localization GO:0008104 205 0.034
cellular response to endogenous stimulus GO:0071495 32 0.034
intracellular transport GO:0046907 77 0.034
negative regulation of cellular metabolic process GO:0031324 95 0.034
Human Fly
regulation of developmental process GO:0050793 684 0.032
response to oxygen levels GO:0070482 22 0.032
actomyosin structure organization GO:0031032 154 0.032
response to osmotic stress GO:0006970 29 0.031
cellular lipid metabolic process GO:0044255 40 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.030
Human Fly
neurological system process GO:0050877 53 0.030
amine metabolic process GO:0009308 15 0.030
neuron differentiation GO:0030182 217 0.030
protein complex biogenesis GO:0070271 186 0.030
defense response to bacterium GO:0042742 86 0.030
regulation of apoptotic signaling pathway GO:2001233 1 0.029
cellular response to organonitrogen compound GO:0071417 14 0.029
regulation of pharyngeal pumping GO:0043051 36 0.029
homeostatic process GO:0042592 51 0.028
Fly
single organism intracellular transport GO:1902582 70 0.028
hermaphrodite genitalia development GO:0040035 734 0.027
regulation of g protein coupled receptor protein signaling pathway GO:0008277 4 0.027
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacterium GO:1902097 4 0.026
regulation of growth GO:0040008 409 0.026
mitotic cell cycle process GO:1903047 194 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.025
cellular amine metabolic process GO:0044106 15 0.025
cell death GO:0008219 547 0.025
cellular macromolecule localization GO:0070727 75 0.025
signal transduction GO:0007165 317 0.025
Human Mouse
mitochondrion organization GO:0007005 20 0.024
reproductive system development GO:0061458 850 0.024
pigmentation GO:0043473 2 0.024
posttranscriptional regulation of gene expression GO:0010608 166 0.023
digestive system development GO:0055123 122 0.023
striated muscle cell development GO:0055002 157 0.023
response to other organism GO:0051707 101 0.023
regulation of lipid biosynthetic process GO:0046890 1 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.023
Human
regulation of molecular function GO:0065009 89 0.022
Human
cellular component assembly involved in morphogenesis GO:0010927 183 0.022
nucleobase containing small molecule metabolic process GO:0055086 115 0.022
anatomical structure formation involved in morphogenesis GO:0048646 250 0.022
cellular protein metabolic process GO:0044267 279 0.022
Human Mouse Worm Fly
cell type specific apoptotic process GO:0097285 4 0.022
establishment of localization in cell GO:0051649 318 0.022
developmental growth GO:0048589 412 0.022
regulation of multi organism process GO:0043900 69 0.022
reproductive structure development GO:0048608 850 0.021
apoptotic cell clearance GO:0043277 111 0.021
response to oxygen containing compound GO:1901700 44 0.021
development of primary sexual characteristics GO:0045137 840 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
nucleoside triphosphate catabolic process GO:0009143 72 0.021
regulation of catalytic activity GO:0050790 78 0.021
cellular protein complex assembly GO:0043623 178 0.021
cellular component morphogenesis GO:0032989 318 0.020
carboxylic acid catabolic process GO:0046395 3 0.020
acetylcholine secretion GO:0061526 11 0.020
negative regulation of cell communication GO:0010648 61 0.020
cellular protein localization GO:0034613 75 0.020
cell motility GO:0048870 313 0.020
catabolic process GO:0009056 318 0.020
Worm
monosaccharide metabolic process GO:0005996 2 0.020
single organism catabolic process GO:0044712 129 0.019
Worm
metal ion transport GO:0030001 49 0.019
peptidyl tyrosine phosphorylation GO:0018108 2 0.019
regulation of locomotion GO:0040012 161 0.019
carbohydrate metabolic process GO:0005975 34 0.019
ribonucleoside catabolic process GO:0042454 77 0.019
organic substance catabolic process GO:1901575 294 0.019
synaptic transmission GO:0007268 106 0.019
regulation of feeding behavior GO:0060259 38 0.019
cellular ketone metabolic process GO:0042180 14 0.019
macromolecule catabolic process GO:0009057 202 0.019
regulation of phosphate metabolic process GO:0019220 81 0.019
Human
negative regulation of rna biosynthetic process GO:1902679 53 0.018
Human Fly
positive regulation of cell death GO:0010942 38 0.018
male sex differentiation GO:0046661 86 0.018
negative regulation of macromolecule metabolic process GO:0010605 229 0.018
Human Fly
striated muscle cell differentiation GO:0051146 158 0.018
response to bacterium GO:0009617 86 0.017
engulfment of apoptotic cell GO:0043652 94 0.017
chromosome segregation GO:0007059 180 0.017
Fly
cellular component movement GO:0006928 388 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 2 0.017
regulation of hormone secretion GO:0046883 2 0.017
protein metabolic process GO:0019538 422 0.016
Human Mouse Worm Fly
purine containing compound catabolic process GO:0072523 75 0.016
regulation of cell death GO:0010941 65 0.016
regulation of synaptic transmission GO:0050804 34 0.016
p38mapk cascade GO:0038066 2 0.016
posttranscriptional gene silencing GO:0016441 143 0.016
gene silencing GO:0016458 143 0.016
Fly
negative regulation of signaling GO:0023057 61 0.016
response to external stimulus GO:0009605 289 0.016
Worm
immune response GO:0006955 192 0.016
positive regulation of developmental process GO:0051094 408 0.016
organic anion transport GO:0015711 20 0.016
single organism carbohydrate metabolic process GO:0044723 29 0.015
monovalent inorganic cation transport GO:0015672 33 0.015
positive regulation of catalytic activity GO:0043085 59 0.015
regulation of oviposition GO:0046662 43 0.015
meiotic cell cycle GO:0051321 335 0.015
Fly
positive regulation of metabolic process GO:0009893 187 0.015
Human Worm Fly
regulation of gene expression epigenetic GO:0040029 163 0.015
Fly
membrane invagination GO:0010324 98 0.015
response to organonitrogen compound GO:0010243 15 0.014
intracellular receptor signaling pathway GO:0030522 2 0.014
ribose phosphate metabolic process GO:0019693 99 0.014
neuron projection morphogenesis GO:0048812 114 0.014
excretion GO:0007588 49 0.014
gene silencing by rna GO:0031047 143 0.014
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 2 0.014
regulation of carbohydrate metabolic process GO:0006109 2 0.014
locomotory behavior GO:0007626 40 0.014
regulation of localization GO:0032879 194 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
myosin filament organization GO:0031033 138 0.014
transmembrane transport GO:0055085 110 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
negative regulation of developmental process GO:0051093 227 0.014
memory GO:0007613 3 0.014
myosin filament assembly GO:0031034 138 0.013
lipid metabolic process GO:0006629 77 0.013
cyclic purine nucleotide metabolic process GO:0052652 2 0.013
positive regulation of cellular process GO:0048522 332 0.013
Human Worm Fly
generation of precursor metabolites and energy GO:0006091 18 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.013
regulation of mitotic cell cycle GO:0007346 76 0.013
organic cyclic compound catabolic process GO:1901361 119 0.013
gonad development GO:0008406 840 0.013
regulation of apoptotic process GO:0042981 36 0.013
cell part morphogenesis GO:0032990 152 0.013
enzyme linked receptor protein signaling pathway GO:0007167 50 0.013
feeding behavior GO:0007631 70 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.013
Human Fly
hormone transport GO:0009914 2 0.013
lipid biosynthetic process GO:0008610 28 0.013
regulation of cell cycle GO:0051726 194 0.012
positive regulation of programmed cell death GO:0043068 27 0.012
purine ribonucleoside metabolic process GO:0046128 92 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
rna interference GO:0016246 137 0.012
regulation of gene silencing GO:0060968 3 0.012
Fly
purine containing compound metabolic process GO:0072521 95 0.012
positive regulation of rna metabolic process GO:0051254 103 0.012
Human Fly
response to extracellular stimulus GO:0009991 38 0.012
Worm
collagen and cuticulin based cuticle development GO:0040002 99 0.012
genitalia development GO:0048806 741 0.012
endocytosis GO:0006897 819 0.011
cellular protein modification process GO:0006464 207 0.011
Human Mouse Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.011
Human Fly
intracellular signal transduction GO:0035556 96 0.011
Human Mouse
carbohydrate biosynthetic process GO:0016051 4 0.011
purine nucleoside metabolic process GO:0042278 92 0.011
purine nucleoside triphosphate catabolic process GO:0009146 72 0.011
cellular response to nitrogen compound GO:1901699 24 0.011
regulation of transport GO:0051049 91 0.011
negative regulation of cellular component organization GO:0051129 33 0.011
cellular response to stress GO:0033554 162 0.011
Worm
vulval development GO:0040025 333 0.011
positive regulation of response to stimulus GO:0048584 55 0.011
Worm
positive regulation of protein metabolic process GO:0051247 45 0.011
Human
negative regulation of transcription dna templated GO:0045892 53 0.011
Human Fly
muscle cell development GO:0055001 158 0.011
regulation of cell projection assembly GO:0060491 3 0.011
phagocytosis engulfment GO:0006911 98 0.011
negative regulation of dna dependent dna replication GO:2000104 1 0.011
muscle structure development GO:0061061 191 0.011
apoptotic mitochondrial changes GO:0008637 2 0.010
receptor mediated endocytosis GO:0006898 715 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
ribonucleotide metabolic process GO:0009259 99 0.010
response to biotic stimulus GO:0009607 101 0.010
copulation GO:0007620 2 0.010
regulation of lipid metabolic process GO:0019216 4 0.010
2 deoxyribonucleotide metabolic process GO:0009394 2 0.010
positive regulation of signaling GO:0023056 66 0.010
response to salt stress GO:0009651 1 0.010
defense response to gram negative bacterium GO:0050829 64 0.010

rskn-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
immune system disease DOID:2914 0 0.014
hematopoietic system disease DOID:74 0 0.014