Caenorhabditis elegans

22 known processes

maco-1 (CELE_D2092.5)

Protein MACO-1

maco-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism reproductive process GO:0044702 1196 0.235
embryo development ending in birth or egg hatching GO:0009792 2992 0.189
locomotion GO:0040011 1634 0.182
embryo development GO:0009790 3052 0.162
developmental process involved in reproduction GO:0003006 1165 0.153
establishment of localization GO:0051234 1171 0.144
multicellular organism reproduction GO:0032504 819 0.143
endocytosis GO:0006897 819 0.142
regulation of gene expression GO:0010468 366 0.127
regulation of metabolic process GO:0019222 478 0.118
gonad development GO:0008406 840 0.114
post embryonic development GO:0009791 2152 0.113
development of primary sexual characteristics GO:0045137 840 0.111
genitalia development GO:0048806 741 0.106
reproductive structure development GO:0048608 850 0.103
transport GO:0006810 1093 0.100
negative regulation of biological process GO:0048519 567 0.098
cellular component movement GO:0006928 388 0.097
sex differentiation GO:0007548 909 0.096
gene expression GO:0010467 412 0.088
regulation of cellular metabolic process GO:0031323 305 0.084
vesicle mediated transport GO:0016192 852 0.082
multicellular organismal aging GO:0010259 812 0.079
multi organism reproductive process GO:0044703 867 0.079
determination of adult lifespan GO:0008340 812 0.078
localization of cell GO:0051674 313 0.074
reproductive system development GO:0061458 850 0.073
regulation of gene expression epigenetic GO:0040029 163 0.073
regulation of biological quality GO:0065008 741 0.073
negative regulation of metabolic process GO:0009892 240 0.071
cell development GO:0048468 696 0.068
cell death GO:0008219 547 0.067
aging GO:0007568 812 0.067
maintenance of location GO:0051235 580 0.066
programmed cell death GO:0012501 500 0.065
organ development GO:0048513 1102 0.065
lipid storage GO:0019915 565 0.062
receptor mediated endocytosis GO:0006898 715 0.062
positive regulation of multicellular organismal process GO:0051240 417 0.061
gene silencing GO:0016458 143 0.061
macromolecule localization GO:0033036 771 0.061
cell motility GO:0048870 313 0.061
multi multicellular organism process GO:0044706 390 0.060
multicellular organismal reproductive process GO:0048609 815 0.059
death GO:0016265 547 0.059
lipid localization GO:0010876 573 0.058
body morphogenesis GO:0010171 620 0.053
regulation of developmental process GO:0050793 684 0.053
neuron differentiation GO:0030182 217 0.053
gamete generation GO:0007276 461 0.053
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.052
heterocycle biosynthetic process GO:0018130 187 0.052
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.051
cell cycle GO:0007049 526 0.050
sexual reproduction GO:0019953 546 0.049
apoptotic process GO:0006915 478 0.048
female gamete generation GO:0007292 254 0.047
rna biosynthetic process GO:0032774 169 0.043
organelle organization GO:0006996 783 0.043
cellular component morphogenesis GO:0032989 318 0.043
negative regulation of cellular process GO:0048523 239 0.042
nucleobase containing compound metabolic process GO:0006139 406 0.042
multi organism reproductive behavior GO:0044705 387 0.042
cellular biosynthetic process GO:0044249 315 0.042
regulation of macromolecule biosynthetic process GO:0010556 189 0.041
response to wounding GO:0009611 4 0.041
cell migration GO:0016477 306 0.040
multi organism behavior GO:0051705 389 0.040
single organism localization GO:1902578 518 0.040
hermaphrodite genitalia development GO:0040035 734 0.038
inductive cell migration GO:0040039 145 0.038
posttranscriptional gene silencing GO:0016441 143 0.038
organic cyclic compound biosynthetic process GO:1901362 195 0.038
aromatic compound biosynthetic process GO:0019438 192 0.038
regulation of nitrogen compound metabolic process GO:0051171 222 0.038
biosynthetic process GO:0009058 323 0.037
regulation of multicellular organismal process GO:0051239 726 0.037
negative regulation of gene expression GO:0010629 217 0.037
regulation of developmental growth GO:0048638 389 0.037
germ cell development GO:0007281 351 0.037
regulation of growth GO:0040008 409 0.037
regulation of biosynthetic process GO:0009889 189 0.036
regulation of multicellular organism growth GO:0040014 373 0.036
protein metabolic process GO:0019538 422 0.036
nucleobase containing compound biosynthetic process GO:0034654 184 0.035
regulation of macromolecule metabolic process GO:0060255 421 0.035
negative regulation of macromolecule metabolic process GO:0010605 229 0.035
oviposition GO:0018991 364 0.035
posttranscriptional gene silencing by rna GO:0035194 143 0.035
negative regulation of gene expression epigenetic GO:0045814 2 0.034
nucleic acid templated transcription GO:0097659 169 0.034
positive regulation of cellular process GO:0048522 332 0.033
chromatin assembly or disassembly GO:0006333 1 0.033
developmental growth GO:0048589 412 0.033
cellular macromolecule biosynthetic process GO:0034645 247 0.032
oogenesis GO:0048477 229 0.032
regulation of localization GO:0032879 194 0.032
reproductive behavior GO:0019098 387 0.032
positive regulation of developmental process GO:0051094 408 0.032
behavior GO:0007610 527 0.031
generation of neurons GO:0048699 235 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.031
positive regulation of developmental growth GO:0048639 354 0.030
negative regulation of multicellular organismal process GO:0051241 236 0.030
regulation of primary metabolic process GO:0080090 292 0.030
neuron projection development GO:0031175 187 0.030
posttranscriptional regulation of gene expression GO:0010608 166 0.030
single organism transport GO:0044765 447 0.030
growth GO:0040007 562 0.030
chemotaxis GO:0006935 120 0.030
regulation of cellular component organization GO:0051128 248 0.029
cell part morphogenesis GO:0032990 152 0.029
cell cycle process GO:0022402 482 0.029
positive regulation of growth GO:0045927 369 0.029
muscle organ morphogenesis GO:0048644 4 0.029
regulation of transcription dna templated GO:0006355 164 0.028
molting cycle GO:0042303 281 0.028
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.028
signaling GO:0023052 401 0.028
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.028
single organism signaling GO:0044700 401 0.028
positive regulation of stress activated mapk cascade GO:0032874 3 0.028
muscle structure development GO:0061061 191 0.027
multicellular organism growth GO:0035264 385 0.027
positive regulation of multicellular organism growth GO:0040018 352 0.027
response to chemical GO:0042221 356 0.027
nervous system development GO:0007399 253 0.027
cellular nitrogen compound biosynthetic process GO:0044271 192 0.027
signal transduction GO:0007165 317 0.026
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.026
rna interference GO:0016246 137 0.026
nucleic acid metabolic process GO:0090304 299 0.026
organic substance biosynthetic process GO:1901576 323 0.026
gene silencing by rna GO:0031047 143 0.026
small molecule metabolic process GO:0044281 186 0.026
cellular localization GO:0051641 360 0.025
catabolic process GO:0009056 318 0.025
negative regulation of developmental process GO:0051093 227 0.025
post embryonic organ development GO:0048569 336 0.025
cellular component assembly GO:0022607 293 0.025
cell projection organization GO:0030030 231 0.025
regulation of nucleic acid templated transcription GO:1903506 165 0.025
organelle fission GO:0048285 363 0.024
macromolecular complex subunit organization GO:0043933 320 0.024
axon development GO:0061564 163 0.024
regulation of vulval development GO:0040028 248 0.024
response to external stimulus GO:0009605 289 0.024
transcription from rna polymerase ii promoter GO:0006366 149 0.024
skeletal muscle organ development GO:0060538 3 0.023
organelle assembly GO:0070925 214 0.023
neurogenesis GO:0022008 236 0.023
regulation of cellular biosynthetic process GO:0031326 189 0.023
regulation of rna metabolic process GO:0051252 173 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.023
transcription dna templated GO:0006351 168 0.023
chromosome segregation GO:0007059 180 0.022
cellular component biogenesis GO:0044085 297 0.022
meiotic chromosome segregation GO:0045132 139 0.022
neuron projection morphogenesis GO:0048812 114 0.022
secretion GO:0046903 147 0.022
regulation of rna biosynthetic process GO:2001141 165 0.022
positive regulation of neurogenesis GO:0050769 4 0.022
cytoskeleton organization GO:0007010 339 0.022
cell division GO:0051301 262 0.022
oxoacid metabolic process GO:0043436 47 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.022
regulation of locomotion GO:0040012 161 0.021
cellular protein modification process GO:0006464 207 0.021
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.021
positive regulation of macromolecule metabolic process GO:0010604 149 0.021
negative regulation of cellular metabolic process GO:0031324 95 0.021
positive regulation of cellular metabolic process GO:0031325 178 0.020
positive regulation of neuron differentiation GO:0045666 4 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.020
macromolecule biosynthetic process GO:0009059 250 0.020
cell projection morphogenesis GO:0048858 148 0.020
epithelial tube morphogenesis GO:0060562 1 0.019
regulation of response to wounding GO:1903034 1 0.019
positive regulation of gene expression GO:0010628 112 0.019
cell morphogenesis GO:0000902 163 0.019
regulation of organelle organization GO:0033043 164 0.019
cellular protein metabolic process GO:0044267 279 0.019
regulation of signaling GO:0023051 172 0.018
regulation of cell cycle GO:0051726 194 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.018
regulation of protein metabolic process GO:0051246 81 0.018
negative regulation of cellular biosynthetic process GO:0031327 65 0.018
regulation of apoptotic signaling pathway GO:2001233 1 0.018
regulation of cytoplasmic transport GO:1903649 3 0.017
macromolecule modification GO:0043412 218 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.017
collagen and cuticulin based cuticle development GO:0040002 99 0.017
cell type specific apoptotic process GO:0097285 4 0.017
positive regulation of metabolic process GO:0009893 187 0.017
regulation of molecular function GO:0065009 89 0.017
actomyosin structure organization GO:0031032 154 0.017
multicellular organismal reproductive behavior GO:0033057 384 0.017
axonogenesis GO:0007409 102 0.017
chromosome organization GO:0051276 104 0.016
cellular response to organic substance GO:0071310 119 0.016
macromolecular complex assembly GO:0065003 193 0.016
anatomical structure formation involved in morphogenesis GO:0048646 250 0.016
vulval development GO:0040025 333 0.016
response to organic substance GO:0010033 131 0.016
neuron projection guidance GO:0097485 82 0.016
positive regulation of jnk cascade GO:0046330 3 0.016
synaptic vesicle endocytosis GO:0048488 3 0.016
organic substance catabolic process GO:1901575 294 0.016
muscle cell differentiation GO:0042692 171 0.016
cell morphogenesis involved in differentiation GO:0000904 112 0.016
protein localization GO:0008104 205 0.016
myosin filament organization GO:0031033 138 0.016
striated muscle cell development GO:0055002 157 0.016
small gtpase mediated signal transduction GO:0007264 32 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
rna metabolic process GO:0016070 228 0.016
regeneration GO:0031099 4 0.015
negative regulation of nucleic acid templated transcription GO:1903507 53 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
muscle cell development GO:0055001 158 0.015
rho protein signal transduction GO:0007266 2 0.015
regulation of organ morphogenesis GO:2000027 4 0.015
regulation of cell division GO:0051302 142 0.015
regulation of multicellular organismal development GO:2000026 317 0.015
cell fate commitment GO:0045165 139 0.015
negative regulation of biosynthetic process GO:0009890 65 0.015
intracellular receptor signaling pathway GO:0030522 2 0.015
meiotic cell cycle process GO:1903046 170 0.015
actin filament based process GO:0030029 191 0.015
neuromuscular junction development GO:0007528 2 0.015
secretion by cell GO:0032940 138 0.015
protein modification process GO:0036211 207 0.015
sensory organ morphogenesis GO:0090596 2 0.015
regulation of post embryonic development GO:0048580 260 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.015
single organism organelle organization GO:1902589 501 0.014
cellular amine metabolic process GO:0044106 15 0.014
phagocytosis GO:0006909 115 0.014
positive regulation of cell migration GO:0030335 3 0.014
amine metabolic process GO:0009308 15 0.014
organic acid metabolic process GO:0006082 47 0.014
embryonic morphogenesis GO:0048598 152 0.014
cellular amino acid metabolic process GO:0006520 15 0.014
regulation of nucleocytoplasmic transport GO:0046822 3 0.014
regulation of hydrolase activity GO:0051336 45 0.014
cell recognition GO:0008037 85 0.014
canonical wnt signaling pathway GO:0060070 3 0.014
striated muscle cell differentiation GO:0051146 158 0.014
cell surface receptor signaling pathway GO:0007166 149 0.014
regulation of cell death GO:0010941 65 0.014
protein complex assembly GO:0006461 186 0.014
regulation of jun kinase activity GO:0043506 3 0.014
regulation of protein import into nucleus GO:0042306 3 0.014
negative regulation of vulval development GO:0040027 206 0.014
regulation of cellular protein metabolic process GO:0032268 75 0.014
response to acid chemical GO:0001101 4 0.014
negative regulation of transcription dna templated GO:0045892 53 0.014
defense response GO:0006952 296 0.013
ribonucleoprotein complex assembly GO:0022618 4 0.013
single organism biosynthetic process GO:0044711 91 0.013
actin cytoskeleton organization GO:0030036 184 0.013
organonitrogen compound metabolic process GO:1901564 151 0.013
axon guidance GO:0007411 82 0.013
positive regulation of intracellular transport GO:0032388 2 0.013
phosphorus metabolic process GO:0006793 232 0.013
regulation of nuclear division GO:0051783 115 0.013
neuron development GO:0048666 199 0.013
positive regulation of rna metabolic process GO:0051254 103 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
taxis GO:0042330 128 0.013
meiotic nuclear division GO:0007126 300 0.013
positive regulation of protein transport GO:0051222 4 0.013
cellular macromolecular complex assembly GO:0034622 184 0.013
positive regulation of transcription dna templated GO:0045893 102 0.013
negative regulation of nematode larval development GO:0061064 208 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
regulation of cell communication GO:0010646 176 0.013
myofibril assembly GO:0030239 154 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
regulation of lipid metabolic process GO:0019216 4 0.012
negative regulation of rna metabolic process GO:0051253 53 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
protein complex subunit organization GO:0071822 280 0.012
regulation of response to stimulus GO:0048583 243 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.012
system process GO:0003008 136 0.012
regulation of reproductive process GO:2000241 66 0.012
muscle tissue development GO:0060537 1 0.012
regulation of programmed cell death GO:0043067 50 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.012
cellular ketone metabolic process GO:0042180 14 0.012
regulation of nematode larval development GO:0061062 260 0.012
regulation of cell migration GO:0030334 55 0.012
regulation of system process GO:0044057 27 0.012
chromatin remodeling GO:0006338 2 0.011
protein catabolic process GO:0030163 162 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
mitotic cell cycle process GO:1903047 194 0.011
response to abiotic stimulus GO:0009628 152 0.011
macromolecule catabolic process GO:0009057 202 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.011
chromatin assembly GO:0031497 1 0.011
positive regulation of rna biosynthetic process GO:1902680 102 0.011
organophosphate metabolic process GO:0019637 125 0.011
protein complex biogenesis GO:0070271 186 0.011
regulation of meiotic cell cycle GO:0051445 136 0.011
negative regulation of post embryonic development GO:0048581 208 0.011
regulation of catalytic activity GO:0050790 78 0.011
tube development GO:0035295 126 0.011
myosin filament assembly GO:0031034 138 0.011
protein oligomerization GO:0051259 4 0.011
head development GO:0060322 1 0.011
regulation of protein targeting GO:1903533 3 0.011
cellular catabolic process GO:0044248 199 0.011
negative regulation of rna biosynthetic process GO:1902679 53 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
adult behavior GO:0030534 3 0.011
tube morphogenesis GO:0035239 79 0.010
negative regulation of neurogenesis GO:0050768 4 0.010
regulation of transport GO:0051049 91 0.010
cellular response to abiotic stimulus GO:0071214 4 0.010
regulation of cell cycle process GO:0010564 145 0.010
phosphorylation GO:0016310 116 0.010
carbohydrate derivative metabolic process GO:1901135 141 0.010
response to temperature stimulus GO:0009266 66 0.010
organic cyclic compound catabolic process GO:1901361 119 0.010
ras protein signal transduction GO:0007265 31 0.010
single organism catabolic process GO:0044712 129 0.010
negative regulation of cell communication GO:0010648 61 0.010
heterocycle catabolic process GO:0046700 119 0.010
regulation of synapse assembly GO:0051963 2 0.010
positive regulation of locomotion GO:0040017 42 0.010
adult locomotory behavior GO:0008344 1 0.010
meiotic cell cycle GO:0051321 335 0.010
epithelial cell proliferation GO:0050673 1 0.010
positive regulation of neuron projection development GO:0010976 4 0.010
nucleobase containing small molecule metabolic process GO:0055086 115 0.010

maco-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011