Caenorhabditis elegans

0 known processes

F01E11.3 (CELE_F01E11.3)

Protein F01E11.3

F01E11.3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.235
embryo development ending in birth or egg hatching GO:0009792 2992 0.230
organ development GO:0048513 1102 0.228
locomotion GO:0040011 1634 0.165
single organism reproductive process GO:0044702 1196 0.161
multicellular organism reproduction GO:0032504 819 0.160
positive regulation of cellular process GO:0048522 332 0.156
developmental process involved in reproduction GO:0003006 1165 0.132
organelle organization GO:0006996 783 0.132
development of primary sexual characteristics GO:0045137 840 0.125
multi organism reproductive process GO:0044703 867 0.125
cell development GO:0048468 696 0.124
sex differentiation GO:0007548 909 0.124
reproductive system development GO:0061458 850 0.123
cell cycle GO:0007049 526 0.119
reproductive structure development GO:0048608 850 0.111
cell morphogenesis GO:0000902 163 0.106
cellular protein metabolic process GO:0044267 279 0.104
protein modification process GO:0036211 207 0.102
cell cycle process GO:0022402 482 0.102
cell projection organization GO:0030030 231 0.099
regulation of vulval development GO:0040028 248 0.099
neurogenesis GO:0022008 236 0.097
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.093
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.093
multicellular organismal reproductive process GO:0048609 815 0.090
regulation of biological quality GO:0065008 741 0.090
head development GO:0060322 1 0.089
macromolecule modification GO:0043412 218 0.089
protein metabolic process GO:0019538 422 0.088
gene expression GO:0010467 412 0.088
signaling GO:0023052 401 0.088
cellular component movement GO:0006928 388 0.086
regulation of multicellular organismal process GO:0051239 726 0.086
establishment of localization in cell GO:0051649 318 0.084
cell part morphogenesis GO:0032990 152 0.082
signal transduction GO:0007165 317 0.081
regulation of cellular component organization GO:0051128 248 0.081
positive regulation of cellular metabolic process GO:0031325 178 0.081
multicellular organismal aging GO:0010259 812 0.079
genitalia development GO:0048806 741 0.079
single organism localization GO:1902578 518 0.079
rna biosynthetic process GO:0032774 169 0.078
single organism transport GO:0044765 447 0.077
macromolecule localization GO:0033036 771 0.077
regulation of developmental process GO:0050793 684 0.077
gonad development GO:0008406 840 0.076
post embryonic development GO:0009791 2152 0.076
cellular component morphogenesis GO:0032989 318 0.076
rna metabolic process GO:0016070 228 0.074
single organism organelle organization GO:1902589 501 0.074
cell motility GO:0048870 313 0.073
regulation of gene expression GO:0010468 366 0.072
regulation of primary metabolic process GO:0080090 292 0.071
regulation of metabolic process GO:0019222 478 0.071
cellular protein modification process GO:0006464 207 0.071
behavior GO:0007610 527 0.070
determination of adult lifespan GO:0008340 812 0.070
establishment of localization GO:0051234 1171 0.068
positive regulation of nucleic acid templated transcription GO:1903508 102 0.068
neuron differentiation GO:0030182 217 0.068
positive regulation of transcription dna templated GO:0045893 102 0.068
organ morphogenesis GO:0009887 67 0.067
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.066
nucleobase containing compound metabolic process GO:0006139 406 0.065
post embryonic organ development GO:0048569 336 0.065
transport GO:0006810 1093 0.064
programmed cell death GO:0012501 500 0.064
sexual reproduction GO:0019953 546 0.064
cellular localization GO:0051641 360 0.064
neuron development GO:0048666 199 0.064
meiotic nuclear division GO:0007126 300 0.064
regulation of locomotion GO:0040012 161 0.063
regulation of transcription dna templated GO:0006355 164 0.063
cytoskeleton organization GO:0007010 339 0.062
generation of neurons GO:0048699 235 0.062
muscle tissue development GO:0060537 1 0.062
positive regulation of macromolecule metabolic process GO:0010604 149 0.061
nucleic acid templated transcription GO:0097659 169 0.061
microtubule based process GO:0007017 182 0.061
localization of cell GO:0051674 313 0.061
apoptotic process GO:0006915 478 0.060
gamete generation GO:0007276 461 0.060
lipid localization GO:0010876 573 0.059
regulation of post embryonic development GO:0048580 260 0.059
nervous system development GO:0007399 253 0.059
lipid storage GO:0019915 565 0.058
maintenance of location GO:0051235 580 0.058
cellular component assembly GO:0022607 293 0.058
death GO:0016265 547 0.057
regulation of macromolecule metabolic process GO:0060255 421 0.057
aging GO:0007568 812 0.056
negative regulation of biological process GO:0048519 567 0.056
cell death GO:0008219 547 0.056
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.055
regulation of nitrogen compound metabolic process GO:0051171 222 0.054
regulation of multicellular organismal development GO:2000026 317 0.054
organic substance catabolic process GO:1901575 294 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.053
sensory organ morphogenesis GO:0090596 2 0.053
response to chemical GO:0042221 356 0.053
cell migration GO:0016477 306 0.053
mitotic cell cycle process GO:1903047 194 0.053
cell morphogenesis involved in differentiation GO:0000904 112 0.052
neuron projection development GO:0031175 187 0.052
vulval development GO:0040025 333 0.051
regulation of macromolecule biosynthetic process GO:0010556 189 0.051
cell surface receptor signaling pathway GO:0007166 149 0.050
regulation of rna metabolic process GO:0051252 173 0.050
cellular component biogenesis GO:0044085 297 0.049
regulation of rna biosynthetic process GO:2001141 165 0.049
cellular macromolecule biosynthetic process GO:0034645 247 0.049
organelle fission GO:0048285 363 0.048
nucleic acid metabolic process GO:0090304 299 0.048
regulation of localization GO:0032879 194 0.047
phosphorus metabolic process GO:0006793 232 0.047
muscle structure development GO:0061061 191 0.047
positive regulation of rna biosynthetic process GO:1902680 102 0.047
negative regulation of multicellular organismal process GO:0051241 236 0.047
multicellular organism growth GO:0035264 385 0.047
regulation of cellular metabolic process GO:0031323 305 0.046
regulation of nucleic acid templated transcription GO:1903506 165 0.045
cell projection morphogenesis GO:0048858 148 0.045
growth GO:0040007 562 0.045
single organism signaling GO:0044700 401 0.045
regulation of cell cycle process GO:0010564 145 0.045
meiotic cell cycle GO:0051321 335 0.044
regulation of biosynthetic process GO:0009889 189 0.044
positive regulation of biosynthetic process GO:0009891 109 0.044
regulation of growth GO:0040008 409 0.044
organic substance biosynthetic process GO:1901576 323 0.043
protein phosphorylation GO:0006468 85 0.043
negative regulation of developmental process GO:0051093 227 0.043
phosphate containing compound metabolic process GO:0006796 232 0.042
regulation of cell cycle GO:0051726 194 0.042
anatomical structure formation involved in morphogenesis GO:0048646 250 0.042
oviposition GO:0018991 364 0.042
regulation of nematode larval development GO:0061062 260 0.041
multi multicellular organism process GO:0044706 390 0.041
developmental growth GO:0048589 412 0.041
positive regulation of multicellular organismal process GO:0051240 417 0.041
regulation of organelle organization GO:0033043 164 0.041
positive regulation of metabolic process GO:0009893 187 0.040
cell fate commitment GO:0045165 139 0.040
regulation of developmental growth GO:0048638 389 0.040
phosphorylation GO:0016310 116 0.040
cell proliferation GO:0008283 116 0.039
hermaphrodite genitalia development GO:0040035 734 0.039
aromatic compound biosynthetic process GO:0019438 192 0.038
macromolecular complex subunit organization GO:0043933 320 0.038
cell division GO:0051301 262 0.038
cellular nitrogen compound biosynthetic process GO:0044271 192 0.038
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.037
catabolic process GO:0009056 318 0.037
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.037
response to external stimulus GO:0009605 289 0.037
neuron projection morphogenesis GO:0048812 114 0.037
regulation of cellular component movement GO:0051270 62 0.036
nucleobase containing compound biosynthetic process GO:0034654 184 0.036
positive regulation of developmental growth GO:0048639 354 0.036
actin cytoskeleton organization GO:0030036 184 0.036
ion transport GO:0006811 113 0.036
multi organism behavior GO:0051705 389 0.036
skeletal muscle organ development GO:0060538 3 0.035
receptor mediated endocytosis GO:0006898 715 0.035
transcription from rna polymerase ii promoter GO:0006366 149 0.035
regulation of response to stimulus GO:0048583 243 0.035
phagocytosis GO:0006909 115 0.035
intracellular signal transduction GO:0035556 96 0.034
macromolecule biosynthetic process GO:0009059 250 0.034
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.034
vesicle mediated transport GO:0016192 852 0.034
biosynthetic process GO:0009058 323 0.034
body morphogenesis GO:0010171 620 0.034
cell cell signaling GO:0007267 118 0.033
regulation of multicellular organism growth GO:0040014 373 0.033
protein catabolic process GO:0030163 162 0.033
regulation of cell motility GO:2000145 57 0.033
macromolecule catabolic process GO:0009057 202 0.032
positive regulation of gene expression GO:0010628 112 0.032
reproductive behavior GO:0019098 387 0.032
multicellular organismal reproductive behavior GO:0033057 384 0.032
protein localization GO:0008104 205 0.031
protein complex subunit organization GO:0071822 280 0.031
chromosome organization GO:0051276 104 0.031
positive regulation of developmental process GO:0051094 408 0.030
regulation of cell migration GO:0030334 55 0.030
positive regulation of growth GO:0045927 369 0.030
regulation of cellular biosynthetic process GO:0031326 189 0.030
negative regulation of gene expression GO:0010629 217 0.030
negative regulation of cellular process GO:0048523 239 0.030
positive regulation of rna metabolic process GO:0051254 103 0.029
cellular component assembly involved in morphogenesis GO:0010927 183 0.029
female gamete generation GO:0007292 254 0.029
multi organism reproductive behavior GO:0044705 387 0.029
cellular catabolic process GO:0044248 199 0.029
positive regulation of catalytic activity GO:0043085 59 0.029
taxis GO:0042330 128 0.028
embryonic morphogenesis GO:0048598 152 0.028
organelle localization GO:0051640 127 0.028
positive regulation of cellular biosynthetic process GO:0031328 109 0.028
response to wounding GO:0009611 4 0.028
regulation of mitotic cell cycle GO:0007346 76 0.027
positive regulation of multicellular organism growth GO:0040018 352 0.027
tissue morphogenesis GO:0048729 65 0.027
negative regulation of macromolecule metabolic process GO:0010605 229 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.027
axon guidance GO:0007411 82 0.027
organic cyclic compound biosynthetic process GO:1901362 195 0.027
cellular biosynthetic process GO:0044249 315 0.026
synaptic transmission GO:0007268 106 0.026
protein complex biogenesis GO:0070271 186 0.026
regulation of cell division GO:0051302 142 0.026
small molecule metabolic process GO:0044281 186 0.026
heterocycle biosynthetic process GO:0018130 187 0.026
cellular response to abiotic stimulus GO:0071214 4 0.026
negative regulation of metabolic process GO:0009892 240 0.025
adult behavior GO:0030534 3 0.025
axon development GO:0061564 163 0.025
apoptotic cell clearance GO:0043277 111 0.025
cell projection assembly GO:0030031 35 0.025
germ cell development GO:0007281 351 0.024
negative regulation of post embryonic development GO:0048581 208 0.024
axonogenesis GO:0007409 102 0.024
organelle assembly GO:0070925 214 0.024
response to abiotic stimulus GO:0009628 152 0.024
endocytosis GO:0006897 819 0.024
actin filament based process GO:0030029 191 0.024
secretion by cell GO:0032940 138 0.024
regulation of nuclear division GO:0051783 115 0.024
regulation of cell differentiation GO:0045595 81 0.024
transcription dna templated GO:0006351 168 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.023
macromolecular complex assembly GO:0065003 193 0.023
cellular protein complex assembly GO:0043623 178 0.023
system process GO:0003008 136 0.023
molting cycle GO:0042303 281 0.023
organonitrogen compound metabolic process GO:1901564 151 0.023
mitotic nuclear division GO:0007067 89 0.022
regulation of molecular function GO:0065009 89 0.022
muscle cell development GO:0055001 158 0.022
oogenesis GO:0048477 229 0.022
chemotaxis GO:0006935 120 0.022
cell type specific apoptotic process GO:0097285 4 0.022
regulation of cell morphogenesis GO:0022604 40 0.022
protein complex assembly GO:0006461 186 0.021
tissue development GO:0009888 112 0.021
regulation of signaling GO:0023051 172 0.021
regulation of cell communication GO:0010646 176 0.021
gene silencing GO:0016458 143 0.021
positive regulation of phosphorus metabolic process GO:0010562 56 0.021
purine nucleoside triphosphate metabolic process GO:0009144 87 0.021
establishment of organelle localization GO:0051656 123 0.020
regulation of phosphorus metabolic process GO:0051174 81 0.020
single organism behavior GO:0044708 83 0.020
regulation of organ morphogenesis GO:2000027 4 0.020
organic cyclic compound catabolic process GO:1901361 119 0.020
regulation of meiosis GO:0040020 94 0.020
regulation of behavior GO:0050795 97 0.020
defense response GO:0006952 296 0.020
engulfment of apoptotic cell GO:0043652 94 0.020
guanosine containing compound catabolic process GO:1901069 48 0.020
nucleobase containing compound catabolic process GO:0034655 114 0.020
canonical wnt signaling pathway GO:0060070 3 0.020
chromosome segregation GO:0007059 180 0.020
muscle cell differentiation GO:0042692 171 0.020
positive regulation of molecular function GO:0044093 61 0.019
secretion GO:0046903 147 0.019
regeneration GO:0031099 4 0.019
locomotory behavior GO:0007626 40 0.019
ribonucleoside metabolic process GO:0009119 98 0.019
regulation of phosphate metabolic process GO:0019220 81 0.019
digestive tract development GO:0048565 122 0.019
striated muscle cell differentiation GO:0051146 158 0.019
positive regulation of post embryonic development GO:0048582 54 0.019
regulation of cell proliferation GO:0042127 105 0.019
cellular macromolecular complex assembly GO:0034622 184 0.018
spindle localization GO:0051653 51 0.018
nucleoside phosphate catabolic process GO:1901292 77 0.018
regulation of signal transduction GO:0009966 135 0.018
posttranscriptional gene silencing by rna GO:0035194 143 0.018
gene silencing by rna GO:0031047 143 0.018
membrane invagination GO:0010324 98 0.018
heterocycle catabolic process GO:0046700 119 0.018
establishment of mitotic spindle localization GO:0040001 41 0.018
cellular response to stress GO:0033554 162 0.018
neuron recognition GO:0008038 83 0.018
regulation of response to wounding GO:1903034 1 0.018
regulation of protein metabolic process GO:0051246 81 0.018
posttranscriptional gene silencing GO:0016441 143 0.018
organophosphate metabolic process GO:0019637 125 0.018
negative regulation of neurogenesis GO:0050768 4 0.018
peptidyl amino acid modification GO:0018193 58 0.018
regulation of anatomical structure morphogenesis GO:0022603 51 0.018
rho protein signal transduction GO:0007266 2 0.018
regulation of cellular protein metabolic process GO:0032268 75 0.018
ribonucleoside triphosphate metabolic process GO:0009199 87 0.017
cell substrate adhesion GO:0031589 1 0.017
regulation of gene expression epigenetic GO:0040029 163 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.017
cellular nitrogen compound catabolic process GO:0044270 119 0.017
digestive system development GO:0055123 122 0.017
epithelial tube morphogenesis GO:0060562 1 0.017
positive regulation of cell migration GO:0030335 3 0.017
small gtpase mediated signal transduction GO:0007264 32 0.017
regulation of reproductive process GO:2000241 66 0.017
purine nucleoside metabolic process GO:0042278 92 0.017
posttranscriptional regulation of gene expression GO:0010608 166 0.016
intracellular receptor signaling pathway GO:0030522 2 0.016
single organism cellular localization GO:1902580 72 0.016
lamellipodium organization GO:0097581 2 0.016
aromatic compound catabolic process GO:0019439 116 0.016
regulation of cell projection organization GO:0031344 38 0.016
neuron projection guidance GO:0097485 82 0.016
rna interference GO:0016246 137 0.016
striated muscle myosin thick filament assembly GO:0071688 138 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
regulation of catalytic activity GO:0050790 78 0.016
cellular response to organic substance GO:0071310 119 0.016
phagocytosis engulfment GO:0006911 98 0.016
adult locomotory behavior GO:0008344 1 0.015
male anatomical structure morphogenesis GO:0090598 78 0.015
epithelial cell proliferation GO:0050673 1 0.015
response to temperature stimulus GO:0009266 66 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
protein oligomerization GO:0051259 4 0.015
microtubule based movement GO:0007018 33 0.015
memory GO:0007613 3 0.015
tube development GO:0035295 126 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.015
detection of external stimulus GO:0009581 4 0.015
neuromuscular junction development GO:0007528 2 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.015
intracellular transport GO:0046907 77 0.015
regulation of meiotic cell cycle GO:0051445 136 0.015
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.015
positive regulation of cell projection organization GO:0031346 4 0.015
digestive tract morphogenesis GO:0048546 76 0.014
myosin filament organization GO:0031033 138 0.014
actomyosin structure organization GO:0031032 154 0.014
dna metabolic process GO:0006259 74 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
striated muscle cell development GO:0055002 157 0.014
response to organic substance GO:0010033 131 0.014
homeostatic process GO:0042592 51 0.014
nucleoside catabolic process GO:0009164 78 0.014
neurological system process GO:0050877 53 0.014
cellular response to chemical stimulus GO:0070887 129 0.014
response to other organism GO:0051707 101 0.014
response to acid chemical GO:0001101 4 0.014
dendrite development GO:0016358 42 0.014
regulation of synapse assembly GO:0051963 2 0.014
positive regulation of phosphate metabolic process GO:0045937 56 0.014
ras protein signal transduction GO:0007265 31 0.014
positive regulation of nematode larval development GO:0061063 54 0.014
oxoacid metabolic process GO:0043436 47 0.013
purine nucleotide catabolic process GO:0006195 75 0.013
establishment of spindle localization GO:0051293 51 0.013
muscle organ morphogenesis GO:0048644 4 0.013
sensory perception GO:0007600 27 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
carbohydrate derivative metabolic process GO:1901135 141 0.013
feeding behavior GO:0007631 70 0.013
myosin filament assembly GO:0031034 138 0.013
positive regulation of intracellular transport GO:0032388 2 0.013
organic acid metabolic process GO:0006082 47 0.013
cell matrix adhesion GO:0007160 1 0.013
nucleoside metabolic process GO:0009116 99 0.013
glycosyl compound metabolic process GO:1901657 100 0.013
myofibril assembly GO:0030239 154 0.013
nucleotide catabolic process GO:0009166 77 0.013
regulation of epithelial cell proliferation GO:0050678 1 0.013
tube morphogenesis GO:0035239 79 0.013
regulation of hormone secretion GO:0046883 2 0.013
wnt signaling pathway GO:0016055 27 0.013
male sex differentiation GO:0046661 86 0.013
single organism catabolic process GO:0044712 129 0.013
response to external biotic stimulus GO:0043207 101 0.013
cell recognition GO:0008037 85 0.013
nucleobase containing small molecule metabolic process GO:0055086 115 0.012
ribonucleotide catabolic process GO:0009261 75 0.012
defense response to bacterium GO:0042742 86 0.012
dorsal ventral axon guidance GO:0033563 19 0.012
amine metabolic process GO:0009308 15 0.012
carbohydrate derivative catabolic process GO:1901136 82 0.012
cellular amine metabolic process GO:0044106 15 0.012
organic substance transport GO:0071702 113 0.012
long term memory GO:0007616 2 0.012
purine ribonucleoside metabolic process GO:0046128 92 0.012
purine ribonucleoside catabolic process GO:0046130 75 0.012
microtubule based transport GO:0010970 19 0.012
negative regulation of cellular metabolic process GO:0031324 95 0.012
asymmetric cell division GO:0008356 36 0.012
internal peptidyl lysine acetylation GO:0018393 3 0.012
inductive cell migration GO:0040039 145 0.012
organonitrogen compound catabolic process GO:1901565 90 0.012
regulation of lipid metabolic process GO:0019216 4 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
ribonucleoside catabolic process GO:0042454 77 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
g protein coupled receptor signaling pathway GO:0007186 46 0.011
purine nucleoside catabolic process GO:0006152 75 0.011
negative regulation of signal transduction GO:0009968 60 0.011
histone modification GO:0016570 30 0.011
lipid metabolic process GO:0006629 77 0.011
regulation of cell death GO:0010941 65 0.011
filopodium assembly GO:0046847 2 0.011
cellular ketone metabolic process GO:0042180 14 0.011
glycosyl compound catabolic process GO:1901658 79 0.011
cellular macromolecule catabolic process GO:0044265 73 0.011
nucleoside phosphate metabolic process GO:0006753 108 0.011
pigmentation GO:0043473 2 0.011
regulation of stem cell differentiation GO:2000736 1 0.011
ion transmembrane transport GO:0034220 91 0.011
negative regulation of neuron differentiation GO:0045665 4 0.011
hormone transport GO:0009914 2 0.011
mitotic spindle organization GO:0007052 81 0.011
chemosensory behavior GO:0007635 33 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.011
negative regulation of cell cycle GO:0045786 53 0.011
ribonucleoside triphosphate catabolic process GO:0009203 72 0.011
positive regulation of phosphorylation GO:0042327 27 0.011
chromatin remodeling GO:0006338 2 0.011
lamellipodium assembly GO:0030032 2 0.011
regulation of cell development GO:0060284 49 0.011
embryonic body morphogenesis GO:0010172 49 0.011
eating behavior GO:0042755 59 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
axonal fasciculation GO:0007413 79 0.011
nucleoside triphosphate metabolic process GO:0009141 87 0.011
nucleoside triphosphate catabolic process GO:0009143 72 0.011
peptidyl tyrosine phosphorylation GO:0018108 2 0.010
cytoskeleton dependent intracellular transport GO:0030705 19 0.010
regulation of jun kinase activity GO:0043506 3 0.010
purine ribonucleotide catabolic process GO:0009154 75 0.010
neuron apoptotic process GO:0051402 4 0.010
regulation of cytoplasmic transport GO:1903649 3 0.010
cilium morphogenesis GO:0060271 33 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
regulation of phosphorylation GO:0042325 45 0.010
negative regulation of response to external stimulus GO:0032102 3 0.010
regulation of intracellular signal transduction GO:1902531 77 0.010
ribonucleotide metabolic process GO:0009259 99 0.010
olfactory behavior GO:0042048 27 0.010

F01E11.3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.012