Caenorhabditis elegans

183 known processes

daf-16 (CELE_R13H8.1)

Protein DAF-16

daf-16 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of primary metabolic process GO:0080090 292 0.766
developmental process involved in reproduction GO:0003006 1165 0.444
Mouse
embryo development ending in birth or egg hatching GO:0009792 2992 0.375
positive regulation of cellular biosynthetic process GO:0031328 109 0.374
dauer larval development GO:0040024 92 0.369
hermaphrodite genitalia development GO:0040035 734 0.354
single organism reproductive process GO:0044702 1196 0.335
Mouse
development of primary sexual characteristics GO:0045137 840 0.320
Mouse
organ development GO:0048513 1102 0.303
Mouse Fly
multicellular organismal reproductive process GO:0048609 815 0.302
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.298
embryo development GO:0009790 3052 0.279
Zebrafish
cell development GO:0048468 696 0.277
Mouse Fly
regulation of rna biosynthetic process GO:2001141 165 0.276
gonad development GO:0008406 840 0.255
Mouse
rna metabolic process GO:0016070 228 0.244
reproductive system development GO:0061458 850 0.243
Mouse
multi organism reproductive process GO:0044703 867 0.234
Mouse
establishment of localization GO:0051234 1171 0.229
sex differentiation GO:0007548 909 0.224
Mouse
determination of adult lifespan GO:0008340 812 0.222
vesicle mediated transport GO:0016192 852 0.214
genitalia development GO:0048806 741 0.209
regulation of gene expression GO:0010468 366 0.194
negative regulation of cellular process GO:0048523 239 0.194
Human Zebrafish Mouse Fly
negative regulation of metabolic process GO:0009892 240 0.187
Human Mouse Fly
endocytosis GO:0006897 819 0.173
single organism localization GO:1902578 518 0.170
regulation of biological quality GO:0065008 741 0.165
Mouse Fly
system process GO:0003008 136 0.162
positive regulation of macromolecule metabolic process GO:0010604 149 0.159
organelle organization GO:0006996 783 0.159
Fly
regulation of multicellular organismal process GO:0051239 726 0.155
small molecule metabolic process GO:0044281 186 0.150
Mouse Fly
locomotion GO:0040011 1634 0.150
post embryonic development GO:0009791 2152 0.150
oogenesis GO:0048477 229 0.149
Mouse
transport GO:0006810 1093 0.147
regulation of developmental process GO:0050793 684 0.147
gamete generation GO:0007276 461 0.146
Mouse
germ cell development GO:0007281 351 0.145
Mouse
receptor mediated endocytosis GO:0006898 715 0.145
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.138
macromolecule localization GO:0033036 771 0.137
Fly
gene expression GO:0010467 412 0.137
nucleic acid metabolic process GO:0090304 299 0.136
single organism organelle organization GO:1902589 501 0.132
Fly
protein metabolic process GO:0019538 422 0.131
Human
reproductive structure development GO:0048608 850 0.130
Mouse
nucleobase containing compound metabolic process GO:0006139 406 0.130
response to external stimulus GO:0009605 289 0.126
regulation of multicellular organism growth GO:0040014 373 0.125
response to chemical GO:0042221 356 0.125
muscle cell differentiation GO:0042692 171 0.124
Fly
transcription dna templated GO:0006351 168 0.123
establishment of localization in cell GO:0051649 318 0.122
developmental growth GO:0048589 412 0.121
organic substance biosynthetic process GO:1901576 323 0.121
macromolecule catabolic process GO:0009057 202 0.120
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.118
Mouse
female gamete generation GO:0007292 254 0.117
Mouse
defense response GO:0006952 296 0.117
body morphogenesis GO:0010171 620 0.116
cell morphogenesis GO:0000902 163 0.112
Fly
organelle localization GO:0051640 127 0.109
macromolecule biosynthetic process GO:0009059 250 0.106
regulation of epithelial cell proliferation GO:0050678 1 0.105
regulation of cellular metabolic process GO:0031323 305 0.104
regulation of lipid biosynthetic process GO:0046890 1 0.103
positive regulation of growth GO:0045927 369 0.102
generation of neurons GO:0048699 235 0.101
Fly
regulation of vulval development GO:0040028 248 0.100
single organism cellular localization GO:1902580 72 0.100
positive regulation of cell communication GO:0010647 69 0.100
Fly
negative regulation of nematode larval development GO:0061064 208 0.098
protein modification process GO:0036211 207 0.097
protein catabolic process GO:0030163 162 0.094
Human
vulval development GO:0040025 333 0.093
cell projection organization GO:0030030 231 0.092
Fly
lipid localization GO:0010876 573 0.092
Fly
regulation of macromolecule biosynthetic process GO:0010556 189 0.091
negative regulation of biological process GO:0048519 567 0.089
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.088
cell fate commitment GO:0045165 139 0.088
regulation of metabolic process GO:0019222 478 0.087
transcription from rna polymerase ii promoter GO:0006366 149 0.086
negative regulation of gene expression GO:0010629 217 0.086
Mouse Fly
cytoskeleton organization GO:0007010 339 0.083
Fly
regulation of nematode larval development GO:0061062 260 0.083
maintenance of location GO:0051235 580 0.081
Fly
regulation of organelle organization GO:0033043 164 0.079
post embryonic organ development GO:0048569 336 0.079
Fly
regulation of rna metabolic process GO:0051252 173 0.079
cellular nitrogen compound biosynthetic process GO:0044271 192 0.078
growth GO:0040007 562 0.078
lipid storage GO:0019915 565 0.078
Fly
negative regulation of developmental process GO:0051093 227 0.077
multicellular organismal aging GO:0010259 812 0.077
positive regulation of developmental growth GO:0048639 354 0.077
sexual reproduction GO:0019953 546 0.076
Mouse
nervous system development GO:0007399 253 0.075
Zebrafish Fly
lipid metabolic process GO:0006629 77 0.073
macromolecule modification GO:0043412 218 0.072
behavior GO:0007610 527 0.071
Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.071
Mouse Fly
negative regulation of vulval development GO:0040027 206 0.071
oxidation reduction process GO:0055114 59 0.070
Fly
cellular biosynthetic process GO:0044249 315 0.070
protein complex subunit organization GO:0071822 280 0.070
programmed cell death GO:0012501 500 0.069
multi multicellular organism process GO:0044706 390 0.069
single organism behavior GO:0044708 83 0.068
Fly
regulation of response to stimulus GO:0048583 243 0.068
embryonic morphogenesis GO:0048598 152 0.067
oviposition GO:0018991 364 0.067
neuron differentiation GO:0030182 217 0.067
Fly
negative regulation of cellular metabolic process GO:0031324 95 0.067
Human Mouse Fly
fatty acid metabolic process GO:0006631 16 0.067
positive regulation of nucleic acid templated transcription GO:1903508 102 0.066
single organism catabolic process GO:0044712 129 0.066
Fly
neuron development GO:0048666 199 0.065
Fly
regulation of growth GO:0040008 409 0.065
cellular localization GO:0051641 360 0.064
protein localization GO:0008104 205 0.064
regulation of post embryonic development GO:0048580 260 0.064
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.064
carboxylic acid metabolic process GO:0019752 34 0.062
head development GO:0060322 1 0.061
epithelial cell proliferation GO:0050673 1 0.061
cell proliferation GO:0008283 116 0.060
Mouse Fly
negative regulation of multicellular organismal process GO:0051241 236 0.060
heterocycle biosynthetic process GO:0018130 187 0.060
cellular component morphogenesis GO:0032989 318 0.059
Fly
neuron projection development GO:0031175 187 0.059
Fly
positive regulation of developmental process GO:0051094 408 0.058
dna metabolic process GO:0006259 74 0.058
aging GO:0007568 812 0.056
regulation of biosynthetic process GO:0009889 189 0.056
multicellular organism reproduction GO:0032504 819 0.055
Mouse
cell projection morphogenesis GO:0048858 148 0.055
Fly
cellular component assembly GO:0022607 293 0.054
homeostatic process GO:0042592 51 0.053
Mouse Fly
single organism transport GO:0044765 447 0.053
aromatic compound biosynthetic process GO:0019438 192 0.053
regulation of locomotion GO:0040012 161 0.053
g protein coupled receptor signaling pathway GO:0007186 46 0.052
Fly
positive regulation of intracellular transport GO:0032388 2 0.052
regulation of localization GO:0032879 194 0.052
Fly
muscle tissue development GO:0060537 1 0.052
regulation of cytoplasmic transport GO:1903649 3 0.052
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.051
multicellular organismal reproductive behavior GO:0033057 384 0.051
regeneration GO:0031099 4 0.051
phosphorylation GO:0016310 116 0.050
Human
negative regulation of post embryonic development GO:0048581 208 0.049
neurogenesis GO:0022008 236 0.049
Fly
multi organism reproductive behavior GO:0044705 387 0.049
biosynthetic process GO:0009058 323 0.049
positive regulation of gene expression GO:0010628 112 0.049
death GO:0016265 547 0.048
macromolecular complex subunit organization GO:0043933 320 0.047
macromolecular complex assembly GO:0065003 193 0.047
neurological system process GO:0050877 53 0.047
positive regulation of multicellular organism growth GO:0040018 352 0.047
positive regulation of epithelial cell proliferation GO:0050679 1 0.047
multicellular organism growth GO:0035264 385 0.046
molting cycle GO:0042303 281 0.046
organic acid metabolic process GO:0006082 47 0.046
cognition GO:0050890 27 0.045
positive regulation of response to stimulus GO:0048584 55 0.045
response to endogenous stimulus GO:0009719 33 0.044
cellular component biogenesis GO:0044085 297 0.044
nucleobase containing compound biosynthetic process GO:0034654 184 0.044
cellular macromolecule biosynthetic process GO:0034645 247 0.044
cellular protein modification process GO:0006464 207 0.043
reproductive behavior GO:0019098 387 0.043
regulation of nitrogen compound metabolic process GO:0051171 222 0.043
cellular response to abiotic stimulus GO:0071214 4 0.043
pattern specification process GO:0007389 59 0.042
immune response GO:0006955 192 0.042
cellular protein metabolic process GO:0044267 279 0.042
regulation of transport GO:0051049 91 0.042
actin filament based process GO:0030029 191 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.041
posttranscriptional regulation of gene expression GO:0010608 166 0.041
multi organism behavior GO:0051705 389 0.041
regulation of multicellular organismal development GO:2000026 317 0.041
Zebrafish
rna localization GO:0006403 3 0.040
response to abiotic stimulus GO:0009628 152 0.040
response to osmotic stress GO:0006970 29 0.040
tissue development GO:0009888 112 0.040
epithelium development GO:0060429 68 0.040
endomembrane system organization GO:0010256 22 0.039
establishment or maintenance of cell polarity GO:0007163 63 0.039
phosphorus metabolic process GO:0006793 232 0.039
Human Fly
regulation of developmental growth GO:0048638 389 0.039
regulation of nucleic acid templated transcription GO:1903506 165 0.039
actin cytoskeleton reorganization GO:0031532 4 0.039
cellular response to hormone stimulus GO:0032870 14 0.039
positive regulation of transport GO:0051050 32 0.038
response to wounding GO:0009611 4 0.038
positive regulation of neuron differentiation GO:0045666 4 0.038
rna biosynthetic process GO:0032774 169 0.037
organelle assembly GO:0070925 214 0.037
anatomical structure formation involved in morphogenesis GO:0048646 250 0.037
Fly
positive regulation of cell projection organization GO:0031346 4 0.036
regulation of nucleocytoplasmic transport GO:0046822 3 0.036
nucleic acid templated transcription GO:0097659 169 0.036
catabolic process GO:0009056 318 0.036
Human Fly
cell death GO:0008219 547 0.036
cellular lipid metabolic process GO:0044255 40 0.035
cell surface receptor signaling pathway GO:0007166 149 0.035
single organism signaling GO:0044700 401 0.035
positive regulation of multicellular organismal process GO:0051240 417 0.035
muscle cell development GO:0055001 158 0.035
actin cytoskeleton organization GO:0030036 184 0.035
oxoacid metabolic process GO:0043436 47 0.035
muscle structure development GO:0061061 191 0.034
Fly
memory GO:0007613 3 0.034
phosphate containing compound metabolic process GO:0006796 232 0.034
Human Fly
cellular component movement GO:0006928 388 0.034
positive regulation of neuron projection development GO:0010976 4 0.034
protein complex assembly GO:0006461 186 0.034
oocyte axis specification GO:0007309 2 0.034
signaling GO:0023052 401 0.033
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.033
membrane organization GO:0061024 135 0.033
organic cyclic compound biosynthetic process GO:1901362 195 0.033
regulation of gene expression epigenetic GO:0040029 163 0.033
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.033
organonitrogen compound metabolic process GO:1901564 151 0.033
Fly
axon development GO:0061564 163 0.033
apoptotic process GO:0006915 478 0.032
positive regulation of cellular metabolic process GO:0031325 178 0.032
positive regulation of neurogenesis GO:0050769 4 0.032
establishment of mitotic spindle orientation GO:0000132 28 0.032
peptidyl amino acid modification GO:0018193 58 0.031
cell cycle process GO:0022402 482 0.031
secretion GO:0046903 147 0.031
striated muscle cell differentiation GO:0051146 158 0.031
Fly
monocarboxylic acid metabolic process GO:0032787 22 0.031
regulation of cellular component organization GO:0051128 248 0.031
Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.031
Mouse
regulation of multi organism process GO:0043900 69 0.031
regulation of response to wounding GO:1903034 1 0.031
response to acid chemical GO:0001101 4 0.030
organic substance catabolic process GO:1901575 294 0.030
Human
synaptic transmission GO:0007268 106 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.030
asymmetric cell division GO:0008356 36 0.030
protein complex biogenesis GO:0070271 186 0.029
nucleotide catabolic process GO:0009166 77 0.029
sensory organ morphogenesis GO:0090596 2 0.029
Fly
regulation of oviposition GO:0046662 43 0.029
cell migration GO:0016477 306 0.029
positive regulation of locomotion GO:0040017 42 0.029
regulation of cell cycle GO:0051726 194 0.029
purine ribonucleotide metabolic process GO:0009150 95 0.029
Fly
ribosome biogenesis GO:0042254 4 0.028
chromosome organization GO:0051276 104 0.028
intracellular transport GO:0046907 77 0.028
histone modification GO:0016570 30 0.028
nucleus organization GO:0006997 38 0.027
positive regulation of cellular process GO:0048522 332 0.027
ion transport GO:0006811 113 0.026
establishment of organelle localization GO:0051656 123 0.026
secretion by cell GO:0032940 138 0.026
cellular ketone metabolic process GO:0042180 14 0.026
Mouse
regulation of meiotic cell cycle GO:0051445 136 0.026
response to other organism GO:0051707 101 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.025
response to organic substance GO:0010033 131 0.025
synaptic vesicle transport GO:0048489 21 0.025
jnk cascade GO:0007254 8 0.025
cellular component assembly involved in morphogenesis GO:0010927 183 0.024
positive regulation of signal transduction GO:0009967 40 0.024
Fly
regulation of cellular component size GO:0032535 40 0.024
Fly
actomyosin structure organization GO:0031032 154 0.024
cell division GO:0051301 262 0.024
striated muscle myosin thick filament assembly GO:0071688 138 0.024
regulation of reproductive process GO:2000241 66 0.024
myofibril assembly GO:0030239 154 0.024
positive regulation of rna metabolic process GO:0051254 103 0.024
cellular catabolic process GO:0044248 199 0.024
Human Fly
gene silencing by rna GO:0031047 143 0.023
response to external biotic stimulus GO:0043207 101 0.023
regulation of signaling GO:0023051 172 0.023
Human Zebrafish Mouse Fly
response to heat GO:0009408 50 0.023
regulation of anatomical structure size GO:0090066 46 0.023
Fly
peptidyl serine phosphorylation GO:0018105 20 0.022
positive regulation of cell migration GO:0030335 3 0.022
striated muscle cell development GO:0055002 157 0.022
cell motility GO:0048870 313 0.022
cellular response to organic substance GO:0071310 119 0.022
response to temperature stimulus GO:0009266 66 0.022
oocyte differentiation GO:0009994 45 0.022
Mouse
positive regulation of biosynthetic process GO:0009891 109 0.022
regulation of transcription dna templated GO:0006355 164 0.022
gene silencing GO:0016458 143 0.022
cellular protein complex assembly GO:0043623 178 0.022
cellular response to dna damage stimulus GO:0006974 41 0.022
response to peptide hormone GO:0043434 14 0.022
amine metabolic process GO:0009308 15 0.021
skeletal muscle organ development GO:0060538 3 0.021
nucleotide metabolic process GO:0009117 108 0.021
Fly
monosaccharide metabolic process GO:0005996 2 0.021
Mouse
cell type specific apoptotic process GO:0097285 4 0.021
Zebrafish
posttranscriptional gene silencing by rna GO:0035194 143 0.021
regulation of cell differentiation GO:0045595 81 0.021
Mouse Fly
single organism biosynthetic process GO:0044711 91 0.021
chemotaxis GO:0006935 120 0.020
cellular amine metabolic process GO:0044106 15 0.020
cellular response to nitrogen compound GO:1901699 24 0.020
rna interference GO:0016246 137 0.020
carbohydrate derivative metabolic process GO:1901135 141 0.020
Fly
negative regulation of transcription dna templated GO:0045892 53 0.020
Mouse Fly
nucleoside triphosphate metabolic process GO:0009141 87 0.020
cation transport GO:0006812 78 0.019
regulation of lipid metabolic process GO:0019216 4 0.019
negative regulation of nucleic acid templated transcription GO:1903507 53 0.019
Mouse Fly
meiotic cell cycle GO:0051321 335 0.019
asymmetric protein localization GO:0008105 35 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
meiotic nuclear division GO:0007126 300 0.018
cellular macromolecular complex assembly GO:0034622 184 0.018
oocyte construction GO:0007308 2 0.018
protein phosphorylation GO:0006468 85 0.018
cell cycle GO:0007049 526 0.018
cell morphogenesis involved in differentiation GO:0000904 112 0.018
Fly
vesicle localization GO:0051648 24 0.018
neuron projection morphogenesis GO:0048812 114 0.018
Fly
cellular amino acid metabolic process GO:0006520 15 0.017
response to extracellular stimulus GO:0009991 38 0.017
Human Fly
lipid biosynthetic process GO:0008610 28 0.017
heterocycle catabolic process GO:0046700 119 0.017
positive regulation of intracellular protein transport GO:0090316 2 0.017
adult behavior GO:0030534 3 0.017
positive regulation of metabolic process GO:0009893 187 0.017
digestive system development GO:0055123 122 0.016
cellular response to chemical stimulus GO:0070887 129 0.016
positive regulation of organ growth GO:0046622 4 0.016
regulation of synapse assembly GO:0051963 2 0.016
cellular nitrogen compound catabolic process GO:0044270 119 0.016
regulation of cell cycle process GO:0010564 145 0.016
regulation of organ morphogenesis GO:2000027 4 0.016
localization of cell GO:0051674 313 0.016
phagocytosis GO:0006909 115 0.016
negative regulation of biosynthetic process GO:0009890 65 0.016
Mouse Fly
mating behavior GO:0007617 32 0.016
cellular response to stress GO:0033554 162 0.016
carbohydrate biosynthetic process GO:0016051 4 0.016
Mouse
posttranscriptional gene silencing GO:0016441 143 0.016
regulation of nuclear division GO:0051783 115 0.016
regulation of cellular localization GO:0060341 42 0.016
ribose phosphate metabolic process GO:0019693 99 0.016
Fly
nucleoside metabolic process GO:0009116 99 0.015
muscle system process GO:0003012 43 0.015
regulation of protein targeting GO:1903533 3 0.015
cellular macromolecule localization GO:0070727 75 0.015
learning or memory GO:0007611 27 0.015
myosin filament organization GO:0031033 138 0.015
regulation of protein import into nucleus GO:0042306 3 0.015
negative regulation of neurogenesis GO:0050768 4 0.015
negative regulation of rna biosynthetic process GO:1902679 53 0.015
Mouse Fly
nitrogen compound transport GO:0071705 49 0.015
cellular response to endogenous stimulus GO:0071495 32 0.015
axonogenesis GO:0007409 102 0.015
regulation of cellular protein metabolic process GO:0032268 75 0.015
engulfment of apoptotic cell GO:0043652 94 0.015
organophosphate metabolic process GO:0019637 125 0.015
Fly
positive regulation of rna biosynthetic process GO:1902680 102 0.014
regulation of cell motility GO:2000145 57 0.014
positive regulation of protein transport GO:0051222 4 0.014
taxis GO:0042330 128 0.014
covalent chromatin modification GO:0016569 30 0.014
regulation of cell migration GO:0030334 55 0.014
hyperosmotic response GO:0006972 19 0.014
rrna processing GO:0006364 3 0.014
regulation of meiosis GO:0040020 94 0.014
positive regulation of chromosome organization GO:2001252 2 0.014
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.014
single organism nuclear import GO:1902593 6 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.014
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.014
regulation of cellular biosynthetic process GO:0031326 189 0.014
response to insulin GO:0032868 14 0.014
intracellular signal transduction GO:0035556 96 0.014
Human Mouse
phagocytosis engulfment GO:0006911 98 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.014
Mouse Fly
organonitrogen compound biosynthetic process GO:1901566 44 0.014
Fly
g1 s transition of mitotic cell cycle GO:0000082 2 0.014
translation GO:0006412 37 0.014
cellular protein localization GO:0034613 75 0.014
negative regulation of cellular component organization GO:0051129 33 0.014
neuromuscular process GO:0050905 1 0.013
response to biotic stimulus GO:0009607 101 0.013
apical junction assembly GO:0043297 1 0.013
synaptic vesicle localization GO:0097479 22 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
chemosensory behavior GO:0007635 33 0.013
regulation of phosphate metabolic process GO:0019220 81 0.013
Human
signal transduction by phosphorylation GO:0023014 31 0.013
Human
regulation of anatomical structure morphogenesis GO:0022603 51 0.013
cellular response to metal ion GO:0071248 3 0.013
regulation of phosphorus metabolic process GO:0051174 81 0.013
Human
oocyte development GO:0048599 44 0.013
Mouse
glycosyl compound metabolic process GO:1901657 100 0.013
rna transport GO:0050658 3 0.013
regulation of protein localization GO:0032880 50 0.013
transmembrane transport GO:0055085 110 0.013
apoptotic cell clearance GO:0043277 111 0.013
regulation of pharyngeal pumping GO:0043051 36 0.013
cell cycle g1 s phase transition GO:0044843 2 0.013
male gamete generation GO:0048232 41 0.013
calcium ion transport GO:0006816 16 0.013
anion transport GO:0006820 30 0.013
dendrite development GO:0016358 42 0.013
Fly
regulation of translation GO:0006417 19 0.013
aromatic compound catabolic process GO:0019439 116 0.012
single organism intracellular transport GO:1902582 70 0.012
signal transduction GO:0007165 317 0.012
negative regulation of response to stimulus GO:0048585 73 0.012
Human Zebrafish Mouse Fly
pharyngeal pumping GO:0043050 58 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
locomotory behavior GO:0007626 40 0.012
Fly
neuromuscular junction development GO:0007528 2 0.012
positive regulation of signaling GO:0023056 66 0.012
Fly
regulation of neurogenesis GO:0050767 40 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
organelle fission GO:0048285 363 0.012
lipid modification GO:0030258 4 0.012
cell cycle phase transition GO:0044770 19 0.012
Mouse
cell cell signaling GO:0007267 118 0.012
regulation of hydrolase activity GO:0051336 45 0.012
myosin filament assembly GO:0031034 138 0.012
calcium mediated signaling GO:0019722 3 0.012
negative regulation of signal transduction GO:0009968 60 0.012
Human Zebrafish Mouse Fly
cellular macromolecule catabolic process GO:0044265 73 0.012
ribonucleoprotein complex assembly GO:0022618 4 0.011
purine nucleotide metabolic process GO:0006163 95 0.011
Fly
protein oligomerization GO:0051259 4 0.011
metal ion transport GO:0030001 49 0.011
nucleic acid transport GO:0050657 3 0.011
negative regulation of cell communication GO:0010648 61 0.011
Human Zebrafish Mouse Fly
rhythmic behavior GO:0007622 3 0.011
Fly
microtubule based process GO:0007017 182 0.011
Fly
regulation of cell development GO:0060284 49 0.011
chromatin organization GO:0006325 32 0.011
sensory perception of bitter taste GO:0050913 3 0.011
organic substance transport GO:0071702 113 0.011
chromatin modification GO:0016568 32 0.011
nucleobase containing small molecule metabolic process GO:0055086 115 0.011
Fly
divalent metal ion transport GO:0070838 17 0.011
regulation of feeding behavior GO:0060259 38 0.011
Fly
digestive tract development GO:0048565 122 0.011
regulation of synaptic transmission GO:0050804 34 0.011
regulation of cell communication GO:0010646 176 0.011
Human Zebrafish Mouse Fly
positive regulation of cellular component organization GO:0051130 34 0.011
positive regulation of transcription dna templated GO:0045893 102 0.011
regulation of catabolic process GO:0009894 57 0.011
Human Fly
nematode male tail tip morphogenesis GO:0045138 77 0.011
negative regulation of catabolic process GO:0009895 9 0.011
regulation of chromatin modification GO:1903308 2 0.011
innate immune response GO:0045087 190 0.011
negative regulation of cellular biosynthetic process GO:0031327 65 0.011
Mouse Fly
establishment of nucleus localization GO:0040023 55 0.011
cell junction organization GO:0034330 18 0.011
regulation of intracellular signal transduction GO:1902531 77 0.011
Human
somatic muscle development GO:0007525 1 0.011
Fly
chromatin remodeling GO:0006338 2 0.011
regulation of calcium ion transport GO:0051924 3 0.011
response to oxidative stress GO:0006979 42 0.010
Mouse Fly
cellular response to inorganic substance GO:0071241 3 0.010
Mouse
defense response to gram negative bacterium GO:0050829 64 0.010
mrna metabolic process GO:0016071 31 0.010
feeding behavior GO:0007631 70 0.010
Fly
regulation of cell proliferation GO:0042127 105 0.010
Mouse Fly
negative regulation of rna metabolic process GO:0051253 53 0.010
Mouse Fly
protein modification by small protein conjugation or removal GO:0070647 40 0.010
response to mechanical stimulus GO:0009612 28 0.010
peptidyl threonine modification GO:0018210 14 0.010
meiotic cell cycle process GO:1903046 170 0.010
organic acid catabolic process GO:0016054 3 0.010
vesicle organization GO:0016050 15 0.010
regulation of molecular function GO:0065009 89 0.010
regulation of g protein coupled receptor protein signaling pathway GO:0008277 4 0.010
Fly
negative regulation of response to external stimulus GO:0032102 3 0.010
synaptic vesicle recycling GO:0036465 3 0.010

daf-16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.076
cancer DOID:162 0 0.024
Human
disease of cellular proliferation DOID:14566 0 0.024
Human
organ system cancer DOID:0050686 0 0.021
Human
disease of metabolism DOID:0014667 0 0.021
nervous system disease DOID:863 0 0.013
musculoskeletal system disease DOID:17 0 0.011