Caenorhabditis elegans

33 known processes

gap-2 (CELE_ZK899.8)

Protein GAP-2

gap-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.217
single organism reproductive process GO:0044702 1196 0.177
dorsal ventral axon guidance GO:0033563 19 0.161
developmental process involved in reproduction GO:0003006 1165 0.160
embryo development GO:0009790 3052 0.153
motor neuron axon guidance GO:0008045 13 0.152
genitalia development GO:0048806 741 0.149
positive regulation of cellular process GO:0048522 332 0.143
Human Mouse
positive regulation of stress activated mapk cascade GO:0032874 3 0.136
Human Mouse
hermaphrodite genitalia development GO:0040035 734 0.134
single organism signaling GO:0044700 401 0.134
positive regulation of neuron projection development GO:0010976 4 0.127
Mouse
behavior GO:0007610 527 0.123
positive regulation of rna biosynthetic process GO:1902680 102 0.116
Human
organ development GO:0048513 1102 0.108
Human Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.103
Human Mouse
signaling GO:0023052 401 0.102
response to external stimulus GO:0009605 289 0.098
Human Mouse
locomotion GO:0040011 1634 0.098
Human Mouse
phosphorus metabolic process GO:0006793 232 0.097
Human Mouse
macromolecule localization GO:0033036 771 0.097
Mouse
positive regulation of cell projection organization GO:0031346 4 0.097
Mouse
positive regulation of intracellular signal transduction GO:1902533 24 0.096
Human Mouse
multicellular organismal aging GO:0010259 812 0.092
multi organism behavior GO:0051705 389 0.092
post embryonic development GO:0009791 2152 0.092
filopodium assembly GO:0046847 2 0.091
guanosine containing compound metabolic process GO:1901068 49 0.089
Human Mouse
cell death GO:0008219 547 0.088
Human Mouse
sex differentiation GO:0007548 909 0.080
regulation of cellular metabolic process GO:0031323 305 0.080
Human Mouse
multi organism reproductive process GO:0044703 867 0.079
synaptic target recognition GO:0008039 3 0.079
positive regulation of molecular function GO:0044093 61 0.078
Human Mouse
phosphate containing compound metabolic process GO:0006796 232 0.078
Human Mouse
multicellular organismal reproductive process GO:0048609 815 0.077
receptor mediated endocytosis GO:0006898 715 0.077
cell motility GO:0048870 313 0.076
Human Mouse
regulation of catabolic process GO:0009894 57 0.075
Human Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.074
single organism cellular localization GO:1902580 72 0.074
Mouse
regulation of mapk cascade GO:0043408 23 0.069
Human Mouse
regulation of behavior GO:0050795 97 0.068
anterior posterior axon guidance GO:0033564 5 0.068
molting cycle GO:0042303 281 0.068
maintenance of location GO:0051235 580 0.068
determination of adult lifespan GO:0008340 812 0.067
lipid storage GO:0019915 565 0.067
development of primary sexual characteristics GO:0045137 840 0.065
cell development GO:0048468 696 0.065
Human Mouse
lipid localization GO:0010876 573 0.061
positive regulation of jnk cascade GO:0046330 3 0.059
Human Mouse
phosphorylation GO:0016310 116 0.059
Human Mouse
regulation of biological quality GO:0065008 741 0.058
Mouse
multicellular organism reproduction GO:0032504 819 0.058
nervous system development GO:0007399 253 0.058
Mouse
regulation of multicellular organismal process GO:0051239 726 0.057
Human Mouse
reproductive structure development GO:0048608 850 0.057
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.056
Human
reproductive system development GO:0061458 850 0.056
cellular localization GO:0051641 360 0.056
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.055
Human
positive regulation of neurogenesis GO:0050769 4 0.055
Mouse
regulation of primary metabolic process GO:0080090 292 0.054
Human Mouse
intracellular signal transduction GO:0035556 96 0.053
positive regulation of gtpase activity GO:0043547 28 0.053
cellular protein modification process GO:0006464 207 0.052
Human Mouse
regulation of developmental process GO:0050793 684 0.051
Human Mouse
cellular component assembly GO:0022607 293 0.049
Human Mouse
endocytosis GO:0006897 819 0.049
positive regulation of catalytic activity GO:0043085 59 0.047
Human Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.046
regulation of nucleoside metabolic process GO:0009118 37 0.046
Human Mouse
regulation of response to stimulus GO:0048583 243 0.045
transport GO:0006810 1093 0.045
Mouse
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.044
response to mechanical stimulus GO:0009612 28 0.043
negative regulation of biological process GO:0048519 567 0.042
regulation of metabolic process GO:0019222 478 0.041
Human Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.041
Human Mouse
aging GO:0007568 812 0.040
regulation of nitrogen compound metabolic process GO:0051171 222 0.040
Human Mouse
regulation of multicellular organismal development GO:2000026 317 0.039
Human Mouse
positive regulation of phosphate metabolic process GO:0045937 56 0.039
Human Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.039
Human Mouse
regulation of gene expression GO:0010468 366 0.039
Human
regulation of gtpase activity GO:0043087 30 0.039
Human Mouse
regulation of cell development GO:0060284 49 0.039
Human Mouse
positive regulation of phosphorus metabolic process GO:0010562 56 0.038
Human Mouse
regulation of small gtpase mediated signal transduction GO:0051056 41 0.038
regulation of molecular function GO:0065009 89 0.037
Human Mouse
rho protein signal transduction GO:0007266 2 0.037
cell projection organization GO:0030030 231 0.037
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.037
Human
ras protein signal transduction GO:0007265 31 0.037
apoptotic process GO:0006915 478 0.036
Human Mouse
developmental growth GO:0048589 412 0.036
lamellipodium organization GO:0097581 2 0.036
defense response to gram negative bacterium GO:0050829 64 0.036
secretion GO:0046903 147 0.035
multi multicellular organism process GO:0044706 390 0.035
regulation of protein localization GO:0032880 50 0.035
Mouse
reproductive behavior GO:0019098 387 0.035
establishment of localization in cell GO:0051649 318 0.035
Mouse
regulation of cellular component movement GO:0051270 62 0.035
Human Mouse
purine containing compound catabolic process GO:0072523 75 0.034
Human Mouse
regulation of phosphate metabolic process GO:0019220 81 0.034
Human Mouse
regulation of ras gtpase activity GO:0032318 21 0.034
Human Mouse
positive regulation of developmental process GO:0051094 408 0.034
Mouse
vesicle mediated transport GO:0016192 852 0.033
localization of cell GO:0051674 313 0.033
Human Mouse
regulation of axon extension GO:0030516 20 0.033
mechanosensory behavior GO:0007638 25 0.033
activation of jun kinase activity GO:0007257 3 0.033
Human
death GO:0016265 547 0.032
Human Mouse
cell type specific apoptotic process GO:0097285 4 0.032
regulation of growth GO:0040008 409 0.032
cell migration GO:0016477 306 0.031
Human Mouse
programmed cell death GO:0012501 500 0.031
Human Mouse
positive regulation of ras gtpase activity GO:0032320 19 0.031
oviposition GO:0018991 364 0.031
regulation of localization GO:0032879 194 0.031
Human Mouse
small gtpase mediated signal transduction GO:0007264 32 0.030
neuron development GO:0048666 199 0.030
Mouse
regulation of cellular component organization GO:0051128 248 0.030
Human Mouse
protein metabolic process GO:0019538 422 0.030
Human Mouse
response to abiotic stimulus GO:0009628 152 0.030
signal transduction GO:0007165 317 0.030
sexual reproduction GO:0019953 546 0.029
protein complex subunit organization GO:0071822 280 0.029
Human Mouse
generation of neurons GO:0048699 235 0.028
Mouse
regulation of intracellular signal transduction GO:1902531 77 0.028
catabolic process GO:0009056 318 0.028
Human Mouse
transcription dna templated GO:0006351 168 0.028
Human
organonitrogen compound catabolic process GO:1901565 90 0.028
Human Mouse
cellular protein metabolic process GO:0044267 279 0.028
Human Mouse
organelle organization GO:0006996 783 0.028
chemotaxis GO:0006935 120 0.028
muscle organ morphogenesis GO:0048644 4 0.028
heterocycle catabolic process GO:0046700 119 0.027
Human Mouse
positive regulation of cell death GO:0010942 38 0.027
Human Mouse
regulation of cell communication GO:0010646 176 0.027
regulation of cellular protein metabolic process GO:0032268 75 0.027
Human Mouse
neuron projection development GO:0031175 187 0.027
Mouse
response to osmotic stress GO:0006970 29 0.026
vulval development GO:0040025 333 0.026
gtp metabolic process GO:0046039 46 0.026
Human Mouse
regulation of developmental growth GO:0048638 389 0.026
regulation of cell cycle GO:0051726 194 0.026
Human
cellular component biogenesis GO:0044085 297 0.026
Human Mouse
dendrite development GO:0016358 42 0.025
Mouse
positive regulation of macromolecule metabolic process GO:0010604 149 0.025
Human Mouse
single organism localization GO:1902578 518 0.025
Mouse
positive regulation of neuron differentiation GO:0045666 4 0.025
Mouse
response to external biotic stimulus GO:0043207 101 0.025
Human Mouse
guanosine containing compound catabolic process GO:1901069 48 0.025
Human Mouse
asymmetric protein localization GO:0008105 35 0.024
membrane organization GO:0061024 135 0.024
regulation of multicellular organism growth GO:0040014 373 0.024
gonad development GO:0008406 840 0.024
multi organism reproductive behavior GO:0044705 387 0.024
regulation of purine nucleotide catabolic process GO:0033121 35 0.024
Human Mouse
muscle tissue development GO:0060537 1 0.024
small molecule metabolic process GO:0044281 186 0.024
Human Mouse
regulation of cell projection organization GO:0031344 38 0.024
Mouse
regulation of purine nucleotide metabolic process GO:1900542 37 0.024
Human Mouse
regulation of transcription dna templated GO:0006355 164 0.023
Human
positive regulation of hydrolase activity GO:0051345 38 0.023
regulation of jun kinase activity GO:0043506 3 0.023
Human Mouse
negative regulation of developmental process GO:0051093 227 0.023
Human Mouse
neuromuscular junction development GO:0007528 2 0.023
regulation of nucleic acid templated transcription GO:1903506 165 0.023
Human
establishment of localization GO:0051234 1171 0.022
Mouse
organophosphate catabolic process GO:0046434 81 0.022
Human Mouse
post embryonic organ development GO:0048569 336 0.022
cellular response to abiotic stimulus GO:0071214 4 0.022
protein localization GO:0008104 205 0.022
Mouse
axon development GO:0061564 163 0.022
cellular macromolecule biosynthetic process GO:0034645 247 0.022
Human
response to other organism GO:0051707 101 0.022
Human Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.022
response to wounding GO:0009611 4 0.022
regulation of extent of cell growth GO:0061387 20 0.022
positive regulation of multicellular organismal process GO:0051240 417 0.021
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.021
nucleobase containing compound catabolic process GO:0034655 114 0.021
Human Mouse
oogenesis GO:0048477 229 0.021
positive regulation of cell migration GO:0030335 3 0.021
Mouse
protein modification process GO:0036211 207 0.021
Human Mouse
aromatic compound biosynthetic process GO:0019438 192 0.021
Human
defense response GO:0006952 296 0.021
nucleoside triphosphate catabolic process GO:0009143 72 0.021
Human Mouse
regulation of axonogenesis GO:0050770 24 0.020
cellular protein complex assembly GO:0043623 178 0.020
organic substance catabolic process GO:1901575 294 0.020
Human Mouse
neuron projection extension GO:1990138 37 0.020
rna metabolic process GO:0016070 228 0.020
Human
negative regulation of multicellular organismal process GO:0051241 236 0.020
Human Mouse
multicellular organism growth GO:0035264 385 0.020
regulation of nervous system development GO:0051960 41 0.020
Mouse
ribose phosphate metabolic process GO:0019693 99 0.020
Human Mouse
cellular nitrogen compound catabolic process GO:0044270 119 0.020
Human Mouse
purine nucleotide metabolic process GO:0006163 95 0.020
Human Mouse
system process GO:0003008 136 0.020
cell growth GO:0016049 44 0.020
organelle assembly GO:0070925 214 0.019
purine ribonucleoside metabolic process GO:0046128 92 0.019
Human Mouse
regulation of actin filament based process GO:0032970 22 0.019
cellular component movement GO:0006928 388 0.019
Human Mouse
regulation of cell cell adhesion GO:0022407 1 0.019
cellular component morphogenesis GO:0032989 318 0.019
Human Mouse
stress activated protein kinase signaling cascade GO:0031098 10 0.018
Human Mouse
regulation of mitotic cell cycle GO:0007346 76 0.018
positive regulation of response to stimulus GO:0048584 55 0.018
Human Mouse
purine ribonucleoside catabolic process GO:0046130 75 0.018
Human Mouse
regulation of neuron projection development GO:0010975 31 0.018
Mouse
neuromuscular process GO:0050905 1 0.018
nucleic acid metabolic process GO:0090304 299 0.018
Human
developmental growth involved in morphogenesis GO:0060560 37 0.018
cellular response to stress GO:0033554 162 0.018
Human Mouse
gtp catabolic process GO:0006184 46 0.018
Human Mouse
positive regulation of gtp catabolic process GO:0033126 28 0.018
positive regulation of metabolic process GO:0009893 187 0.018
Human Mouse
regulation of response to wounding GO:1903034 1 0.018
posttranscriptional gene silencing GO:0016441 143 0.017
positive regulation of signal transduction GO:0009967 40 0.017
Human Mouse
response to chemical GO:0042221 356 0.017
Human Mouse
mapk cascade GO:0000165 31 0.017
Human Mouse
axon extension GO:0048675 37 0.017
macromolecule modification GO:0043412 218 0.017
Human Mouse
positive regulation of multicellular organism growth GO:0040018 352 0.017
head development GO:0060322 1 0.017
Mouse
negative regulation of transmembrane transport GO:0034763 3 0.017
organic substance transport GO:0071702 113 0.017
Mouse
dephosphorylation GO:0016311 17 0.017
regulation of nematode larval development GO:0061062 260 0.017
apoptotic cell clearance GO:0043277 111 0.016
positive regulation of developmental growth GO:0048639 354 0.016
establishment of spindle localization GO:0051293 51 0.016
cell matrix adhesion GO:0007160 1 0.016
purine nucleoside metabolic process GO:0042278 92 0.016
Human Mouse
cytoskeleton organization GO:0007010 339 0.016
lamellipodium assembly GO:0030032 2 0.016
positive regulation of cellular component organization GO:0051130 34 0.016
Mouse
regulation of cell death GO:0010941 65 0.016
Human Mouse
spindle organization GO:0007051 92 0.016
positive regulation of nucleotide catabolic process GO:0030813 28 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
neuron recognition GO:0008038 83 0.016
oocyte differentiation GO:0009994 45 0.016
synapse organization GO:0050808 24 0.016
Mouse
microtubule based movement GO:0007018 33 0.016
nucleobase containing compound metabolic process GO:0006139 406 0.016
Human Mouse
neurogenesis GO:0022008 236 0.016
Mouse
protein complex assembly GO:0006461 186 0.016
Human Mouse
meiotic cell cycle GO:0051321 335 0.016
regulation of phosphorus metabolic process GO:0051174 81 0.015
Human Mouse
synaptic growth at neuromuscular junction GO:0051124 1 0.015
cell recognition GO:0008037 85 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
regulation of catalytic activity GO:0050790 78 0.015
Human Mouse
positive regulation of nucleoside metabolic process GO:0045979 28 0.015
purine ribonucleotide catabolic process GO:0009154 75 0.015
Human Mouse
regulation of synapse assembly GO:0051963 2 0.015
organonitrogen compound metabolic process GO:1901564 151 0.015
Human Mouse
positive regulation of cell development GO:0010720 6 0.015
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.015
Human Mouse
positive regulation of cell adhesion GO:0045785 1 0.015
gamete generation GO:0007276 461 0.015
regulation of hydrolase activity GO:0051336 45 0.015
Human Mouse
regulation of nucleotide catabolic process GO:0030811 35 0.015
Human Mouse
regulation of ras protein signal transduction GO:0046578 41 0.015
positive regulation of growth GO:0045927 369 0.014
defense response to bacterium GO:0042742 86 0.014
regulation of signal transduction GO:0009966 135 0.014
epidermis development GO:0008544 24 0.014
excretion GO:0007588 49 0.014
regulation of signaling GO:0023051 172 0.014
striated muscle cell differentiation GO:0051146 158 0.014
positive chemotaxis GO:0050918 3 0.014
feeding behavior GO:0007631 70 0.014
ribonucleoside metabolic process GO:0009119 98 0.014
Human Mouse
regulation of cellular localization GO:0060341 42 0.014
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 72 0.014
Human Mouse
protein localization to membrane GO:0072657 11 0.014
actin cytoskeleton reorganization GO:0031532 4 0.014
actin cytoskeleton organization GO:0030036 184 0.014
positive regulation of cdc42 gtpase activity GO:0043089 3 0.014
organelle fission GO:0048285 363 0.014
regulation of cell morphogenesis GO:0022604 40 0.014
Human
regeneration GO:0031099 4 0.014
regulation of canonical wnt signaling pathway GO:0060828 1 0.013
Human
protein polymerization GO:0051258 26 0.013
positive regulation of cellular catabolic process GO:0031331 35 0.013
Human
single organism organelle organization GO:1902589 501 0.013
regulation of gtp catabolic process GO:0033124 32 0.013
Human Mouse
purine nucleoside triphosphate catabolic process GO:0009146 72 0.013
Human Mouse
glycosyl compound metabolic process GO:1901657 100 0.013
Human Mouse
negative regulation of protein metabolic process GO:0051248 27 0.013
Human Mouse
negative regulation of cellular process GO:0048523 239 0.013
actomyosin structure organization GO:0031032 154 0.013
positive regulation of rna metabolic process GO:0051254 103 0.013
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
defense response to other organism GO:0098542 100 0.013
positive regulation of cell communication GO:0010647 69 0.013
Human Mouse
cellular macromolecular complex assembly GO:0034622 184 0.013
female gamete generation GO:0007292 254 0.013
actin filament based process GO:0030029 191 0.013
formation of anatomical boundary GO:0048859 1 0.013
ribonucleoprotein complex assembly GO:0022618 4 0.013
purine nucleotide catabolic process GO:0006195 75 0.013
Human Mouse
positive regulation of protein transport GO:0051222 4 0.013
microtubule polymerization or depolymerization GO:0031109 22 0.013
protein oligomerization GO:0051259 4 0.013
macromolecular complex subunit organization GO:0043933 320 0.013
Human Mouse
hormone secretion GO:0046879 2 0.013
regulation of protein serine threonine kinase activity GO:0071900 18 0.013
Human Mouse
actin filament bundle assembly GO:0051017 3 0.013
carboxylic acid metabolic process GO:0019752 34 0.013
positive regulation of synapse assembly GO:0051965 1 0.013
growth GO:0040007 562 0.013
cellular biosynthetic process GO:0044249 315 0.012
Human
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.012
negative regulation of cell communication GO:0010648 61 0.012
aromatic compound catabolic process GO:0019439 116 0.012
Human Mouse
cell maturation GO:0048469 26 0.012
regulation of protein targeting GO:1903533 3 0.012
Mouse
response to bacterium GO:0009617 86 0.012
Human Mouse
neuron projection guidance GO:0097485 82 0.012
canonical wnt signaling pathway GO:0060070 3 0.012
Human
amine metabolic process GO:0009308 15 0.012
regulation of cell size GO:0008361 30 0.012
response to heat GO:0009408 50 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.012
Human Mouse
regulation of apoptotic signaling pathway GO:2001233 1 0.012
Human
myosin filament organization GO:0031033 138 0.012
dauer larval development GO:0040024 92 0.012
cell proliferation GO:0008283 116 0.012
Human Mouse
positive regulation of protein modification process GO:0031401 29 0.012
Human Mouse
microtubule based process GO:0007017 182 0.012
gene silencing GO:0016458 143 0.012
gene silencing by rna GO:0031047 143 0.012
homeostatic process GO:0042592 51 0.012
single organism behavior GO:0044708 83 0.012
nitrogen compound transport GO:0071705 49 0.012
organic substance biosynthetic process GO:1901576 323 0.012
Human
regulation of post embryonic development GO:0048580 260 0.012
cell cycle GO:0007049 526 0.012
Human
carbohydrate derivative catabolic process GO:1901136 82 0.012
Human Mouse
positive regulation of phosphorylation GO:0042327 27 0.012
Human Mouse
male anatomical structure morphogenesis GO:0090598 78 0.012
positive regulation of signaling GO:0023056 66 0.012
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.012
Human
regulation of filopodium assembly GO:0051489 2 0.011
regulation of organelle organization GO:0033043 164 0.011
single organism membrane organization GO:0044802 35 0.011
defense response to fungus GO:0050832 19 0.011
nucleotide catabolic process GO:0009166 77 0.011
Human Mouse
regulation of cytoplasmic transport GO:1903649 3 0.011
Mouse
purine containing compound metabolic process GO:0072521 95 0.011
Human Mouse
body morphogenesis GO:0010171 620 0.011
regulation of cytoskeleton organization GO:0051493 41 0.011
macromolecular complex assembly GO:0065003 193 0.011
Human Mouse
regulation of secretion GO:0051046 29 0.011
regulation of cell proliferation GO:0042127 105 0.011
Human Mouse
developmental cell growth GO:0048588 39 0.011
heterocycle biosynthetic process GO:0018130 187 0.011
Human
rna biosynthetic process GO:0032774 169 0.011
Human
positive regulation of axonogenesis GO:0050772 4 0.011
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.011
Human
sensory organ morphogenesis GO:0090596 2 0.011
negative regulation of response to external stimulus GO:0032102 3 0.011
organelle localization GO:0051640 127 0.011
immune response GO:0006955 192 0.010
nucleus localization GO:0051647 55 0.010
ribonucleotide metabolic process GO:0009259 99 0.010
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 102 0.010
Human
actin filament based movement GO:0030048 4 0.010
regulation of transport GO:0051049 91 0.010
Mouse
endomembrane system organization GO:0010256 22 0.010
positive regulation of transcription dna templated GO:0045893 102 0.010
Human
establishment of organelle localization GO:0051656 123 0.010
oxoacid metabolic process GO:0043436 47 0.010
regulation of reproductive process GO:2000241 66 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.010
response to oxidative stress GO:0006979 42 0.010

gap-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
disease of anatomical entity DOID:7 0 0.013
gastrointestinal system cancer DOID:3119 0 0.011