Caenorhabditis elegans

33 known processes

gap-2 (CELE_ZK899.8)

Protein GAP-2

gap-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.217
single organism reproductive process GO:0044702 1196 0.177
dorsal ventral axon guidance GO:0033563 19 0.161
developmental process involved in reproduction GO:0003006 1165 0.160
embryo development GO:0009790 3052 0.153
motor neuron axon guidance GO:0008045 13 0.152
genitalia development GO:0048806 741 0.149
positive regulation of cellular process GO:0048522 332 0.143
Human Mouse
positive regulation of stress activated mapk cascade GO:0032874 3 0.136
Human Mouse
hermaphrodite genitalia development GO:0040035 734 0.134
single organism signaling GO:0044700 401 0.134
positive regulation of neuron projection development GO:0010976 4 0.127
Mouse
behavior GO:0007610 527 0.123
positive regulation of rna biosynthetic process GO:1902680 102 0.116
Human
organ development GO:0048513 1102 0.108
Human Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.103
Human Mouse
signaling GO:0023052 401 0.102
response to external stimulus GO:0009605 289 0.098
Human Mouse
locomotion GO:0040011 1634 0.098
Human Mouse
phosphorus metabolic process GO:0006793 232 0.097
Human Mouse
macromolecule localization GO:0033036 771 0.097
Mouse
positive regulation of cell projection organization GO:0031346 4 0.097
Mouse
positive regulation of intracellular signal transduction GO:1902533 24 0.096
Human Mouse
multicellular organismal aging GO:0010259 812 0.092
multi organism behavior GO:0051705 389 0.092
post embryonic development GO:0009791 2152 0.092
filopodium assembly GO:0046847 2 0.091
guanosine containing compound metabolic process GO:1901068 49 0.089
Human Mouse
cell death GO:0008219 547 0.088
Human Mouse
sex differentiation GO:0007548 909 0.080
regulation of cellular metabolic process GO:0031323 305 0.080
Human Mouse
multi organism reproductive process GO:0044703 867 0.079
synaptic target recognition GO:0008039 3 0.079
positive regulation of molecular function GO:0044093 61 0.078
Human Mouse
phosphate containing compound metabolic process GO:0006796 232 0.078
Human Mouse
multicellular organismal reproductive process GO:0048609 815 0.077
receptor mediated endocytosis GO:0006898 715 0.077
cell motility GO:0048870 313 0.076
Human Mouse
regulation of catabolic process GO:0009894 57 0.075
Human Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.074
single organism cellular localization GO:1902580 72 0.074
Mouse
regulation of mapk cascade GO:0043408 23 0.069
Human Mouse
regulation of behavior GO:0050795 97 0.068
anterior posterior axon guidance GO:0033564 5 0.068
molting cycle GO:0042303 281 0.068
maintenance of location GO:0051235 580 0.068
determination of adult lifespan GO:0008340 812 0.067
lipid storage GO:0019915 565 0.067
development of primary sexual characteristics GO:0045137 840 0.065
cell development GO:0048468 696 0.065
Human Mouse
lipid localization GO:0010876 573 0.061
positive regulation of jnk cascade GO:0046330 3 0.059
Human Mouse
phosphorylation GO:0016310 116 0.059
Human Mouse
regulation of biological quality GO:0065008 741 0.058
Mouse
multicellular organism reproduction GO:0032504 819 0.058
nervous system development GO:0007399 253 0.058
Mouse
regulation of multicellular organismal process GO:0051239 726 0.057
Human Mouse
reproductive structure development GO:0048608 850 0.057
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.056
Human
reproductive system development GO:0061458 850 0.056
cellular localization GO:0051641 360 0.056
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.055
Human
positive regulation of neurogenesis GO:0050769 4 0.055
Mouse
regulation of primary metabolic process GO:0080090 292 0.054
Human Mouse
intracellular signal transduction GO:0035556 96 0.053
positive regulation of gtpase activity GO:0043547 28 0.053
cellular protein modification process GO:0006464 207 0.052
Human Mouse
regulation of developmental process GO:0050793 684 0.051
Human Mouse
cellular component assembly GO:0022607 293 0.049
Human Mouse
endocytosis GO:0006897 819 0.049
positive regulation of catalytic activity GO:0043085 59 0.047
Human Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.046
regulation of nucleoside metabolic process GO:0009118 37 0.046
Human Mouse
regulation of response to stimulus GO:0048583 243 0.045
transport GO:0006810 1093 0.045
Mouse
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.044
response to mechanical stimulus GO:0009612 28 0.043
negative regulation of biological process GO:0048519 567 0.042
regulation of metabolic process GO:0019222 478 0.041
Human Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.041
Human Mouse
aging GO:0007568 812 0.040
regulation of nitrogen compound metabolic process GO:0051171 222 0.040
Human Mouse
regulation of multicellular organismal development GO:2000026 317 0.039
Human Mouse
positive regulation of phosphate metabolic process GO:0045937 56 0.039
Human Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.039
Human Mouse
regulation of gene expression GO:0010468 366 0.039
Human
regulation of gtpase activity GO:0043087 30 0.039
Human Mouse
regulation of cell development GO:0060284 49 0.039
Human Mouse
positive regulation of phosphorus metabolic process GO:0010562 56 0.038
Human Mouse
regulation of small gtpase mediated signal transduction GO:0051056 41 0.038
regulation of molecular function GO:0065009 89 0.037
Human Mouse
rho protein signal transduction GO:0007266 2 0.037
cell projection organization GO:0030030 231 0.037
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.037
Human
ras protein signal transduction GO:0007265 31 0.037
apoptotic process GO:0006915 478 0.036
Human Mouse
developmental growth GO:0048589 412 0.036
lamellipodium organization GO:0097581 2 0.036
defense response to gram negative bacterium GO:0050829 64 0.036
secretion GO:0046903 147 0.035
multi multicellular organism process GO:0044706 390 0.035
regulation of protein localization GO:0032880 50 0.035
Mouse
reproductive behavior GO:0019098 387 0.035
establishment of localization in cell GO:0051649 318 0.035
Mouse
regulation of cellular component movement GO:0051270 62 0.035
Human Mouse
purine containing compound catabolic process GO:0072523 75 0.034
Human Mouse
regulation of phosphate metabolic process GO:0019220 81 0.034
Human Mouse
regulation of ras gtpase activity GO:0032318 21 0.034
Human Mouse
positive regulation of developmental process GO:0051094 408 0.034
Mouse
vesicle mediated transport GO:0016192 852 0.033
localization of cell GO:0051674 313 0.033
Human Mouse
regulation of axon extension GO:0030516 20 0.033
mechanosensory behavior GO:0007638 25 0.033
activation of jun kinase activity GO:0007257 3 0.033
Human
death GO:0016265 547 0.032
Human Mouse
cell type specific apoptotic process GO:0097285 4 0.032
regulation of growth GO:0040008 409 0.032
cell migration GO:0016477 306 0.031
Human Mouse
programmed cell death GO:0012501 500 0.031
Human Mouse
positive regulation of ras gtpase activity GO:0032320 19 0.031
oviposition GO:0018991 364 0.031
regulation of localization GO:0032879 194 0.031
Human Mouse
small gtpase mediated signal transduction GO:0007264 32 0.030
neuron development GO:0048666 199 0.030
Mouse
regulation of cellular component organization GO:0051128 248 0.030
Human Mouse
protein metabolic process GO:0019538 422 0.030
Human Mouse
response to abiotic stimulus GO:0009628 152 0.030
signal transduction GO:0007165 317 0.030
sexual reproduction GO:0019953 546 0.029
protein complex subunit organization GO:0071822 280 0.029
Human Mouse
generation of neurons GO:0048699 235 0.028
Mouse
regulation of intracellular signal transduction GO:1902531 77 0.028
catabolic process GO:0009056 318 0.028
Human Mouse
transcription dna templated GO:0006351 168 0.028
Human
organonitrogen compound catabolic process GO:1901565 90 0.028
Human Mouse
cellular protein metabolic process GO:0044267 279 0.028
Human Mouse
organelle organization GO:0006996 783 0.028
chemotaxis GO:0006935 120 0.028
muscle organ morphogenesis GO:0048644 4 0.028
heterocycle catabolic process GO:0046700 119 0.027
Human Mouse
positive regulation of cell death GO:0010942 38 0.027
Human Mouse
regulation of cell communication GO:0010646 176 0.027
regulation of cellular protein metabolic process GO:0032268 75 0.027
Human Mouse
neuron projection development GO:0031175 187 0.027
Mouse
response to osmotic stress GO:0006970 29 0.026
vulval development GO:0040025 333 0.026
gtp metabolic process GO:0046039 46 0.026
Human Mouse
regulation of developmental growth GO:0048638 389 0.026
regulation of cell cycle GO:0051726 194 0.026
Human
cellular component biogenesis GO:0044085 297 0.026
Human Mouse
dendrite development GO:0016358 42 0.025
Mouse
positive regulation of macromolecule metabolic process GO:0010604 149 0.025
Human Mouse
single organism localization GO:1902578 518 0.025
Mouse
positive regulation of neuron differentiation GO:0045666 4 0.025
Mouse
response to external biotic stimulus GO:0043207 101 0.025
Human Mouse
guanosine containing compound catabolic process GO:1901069 48 0.025
Human Mouse
asymmetric protein localization GO:0008105 35 0.024
membrane organization GO:0061024 135 0.024
regulation of multicellular organism growth GO:0040014 373 0.024
gonad development GO:0008406 840 0.024
multi organism reproductive behavior GO:0044705 387 0.024
regulation of purine nucleotide catabolic process GO:0033121 35 0.024
Human Mouse
muscle tissue development GO:0060537 1 0.024
small molecule metabolic process GO:0044281 186 0.024
Human Mouse
regulation of cell projection organization GO:0031344 38 0.024
Mouse
regulation of purine nucleotide metabolic process GO:1900542 37 0.024
Human Mouse
regulation of transcription dna templated GO:0006355 164 0.023
Human
positive regulation of hydrolase activity GO:0051345 38 0.023
regulation of jun kinase activity GO:0043506 3 0.023
Human Mouse
negative regulation of developmental process GO:0051093 227 0.023
Human Mouse
neuromuscular junction development GO:0007528 2 0.023
regulation of nucleic acid templated transcription GO:1903506 165 0.023
Human
establishment of localization GO:0051234 1171 0.022
Mouse
organophosphate catabolic process GO:0046434 81 0.022
Human Mouse
post embryonic organ development GO:0048569 336 0.022
cellular response to abiotic stimulus GO:0071214 4 0.022
protein localization GO:0008104 205 0.022
Mouse
axon development GO:0061564 163 0.022
cellular macromolecule biosynthetic process GO:0034645 247 0.022
Human
response to other organism GO:0051707 101 0.022
Human Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.022
response to wounding GO:0009611 4 0.022
regulation of extent of cell growth GO:0061387 20 0.022
positive regulation of multicellular organismal process GO:0051240 417 0.021
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.021
nucleobase containing compound catabolic process GO:0034655 114 0.021
Human Mouse
oogenesis GO:0048477 229 0.021
positive regulation of cell migration GO:0030335 3 0.021
Mouse
protein modification process GO:0036211 207 0.021
Human Mouse
aromatic compound biosynthetic process GO:0019438 192 0.021
Human
defense response GO:0006952 296 0.021
nucleoside triphosphate catabolic process GO:0009143 72 0.021
Human Mouse
regulation of axonogenesis GO:0050770 24 0.020
cellular protein complex assembly GO:0043623 178 0.020
organic substance catabolic process GO:1901575 294 0.020
Human Mouse
neuron projection extension GO:1990138 37 0.020
rna metabolic process GO:0016070 228 0.020
Human
negative regulation of multicellular organismal process GO:0051241 236 0.020
Human Mouse
multicellular organism growth GO:0035264 385 0.020
regulation of nervous system development GO:0051960 41 0.020
Mouse
ribose phosphate metabolic process GO:0019693 99 0.020
Human Mouse
cellular nitrogen compound catabolic process GO:0044270 119 0.020
Human Mouse
purine nucleotide metabolic process GO:0006163 95 0.020
Human Mouse
system process GO:0003008 136 0.020
cell growth GO:0016049 44 0.020
organelle assembly GO:0070925 214 0.019
purine ribonucleoside metabolic process GO:0046128 92 0.019
Human Mouse
regulation of actin filament based process GO:0032970 22 0.019
cellular component movement GO:0006928 388 0.019
Human Mouse
regulation of cell cell adhesion GO:0022407 1 0.019
cellular component morphogenesis GO:0032989 318 0.019
Human Mouse
stress activated protein kinase signaling cascade GO:0031098 10 0.018
Human Mouse
regulation of mitotic cell cycle GO:0007346 76 0.018
positive regulation of response to stimulus GO:0048584 55 0.018
Human Mouse
purine ribonucleoside catabolic process GO:0046130 75 0.018
Human Mouse
regulation of neuron projection development GO:0010975 31 0.018
Mouse
neuromuscular process GO:0050905 1 0.018
nucleic acid metabolic process GO:0090304 299 0.018
Human
developmental growth involved in morphogenesis GO:0060560 37 0.018
cellular response to stress GO:0033554 162 0.018
Human Mouse
gtp catabolic process GO:0006184 46 0.018
Human Mouse
positive regulation of gtp catabolic process GO:0033126 28 0.018
positive regulation of metabolic process GO:0009893 187 0.018
Human Mouse
regulation of response to wounding GO:1903034 1 0.018
posttranscriptional gene silencing GO:0016441 143 0.017
positive regulation of signal transduction GO:0009967 40 0.017
Human Mouse
response to chemical GO:0042221 356 0.017
Human Mouse
mapk cascade GO:0000165 31 0.017
Human Mouse
axon extension GO:0048675 37 0.017
macromolecule modification GO:0043412 218 0.017
Human Mouse
positive regulation of multicellular organism growth GO:0040018 352 0.017
head development GO:0060322 1 0.017
Mouse
negative regulation of transmembrane transport GO:0034763 3 0.017
organic substance transport GO:0071702 113 0.017
Mouse
dephosphorylation GO:0016311 17 0.017
regulation of nematode larval development GO:0061062 260 0.017
apoptotic cell clearance GO:0043277 111 0.016
positive regulation of developmental growth GO:0048639 354 0.016
establishment of spindle localization GO:0051293 51 0.016
cell matrix adhesion GO:0007160 1 0.016
purine nucleoside metabolic process GO:0042278 92 0.016
Human Mouse
cytoskeleton organization GO:0007010 339 0.016
lamellipodium assembly GO:0030032 2 0.016
positive regulation of cellular component organization GO:0051130 34 0.016
Mouse
regulation of cell death GO:0010941 65 0.016
Human Mouse
spindle organization GO:0007051 92 0.016
positive regulation of nucleotide catabolic process GO:0030813 28 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
neuron recognition GO:0008038 83 0.016
oocyte differentiation GO:0009994 45 0.016
synapse organization GO:0050808 24 0.016
Mouse
microtubule based movement GO:0007018 33 0.016
nucleobase containing compound metabolic process GO:0006139 406 0.016
Human Mouse
neurogenesis GO:0022008 236 0.016
Mouse
protein complex assembly GO:0006461 186 0.016
Human Mouse
meiotic cell cycle GO:0051321 335 0.016
regulation of phosphorus metabolic process GO:0051174 81 0.015
Human Mouse
synaptic growth at neuromuscular junction GO:0051124 1 0.015
cell recognition GO:0008037 85 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
regulation of catalytic activity GO:0050790 78 0.015
Human Mouse
positive regulation of nucleoside metabolic process GO:0045979 28 0.015
purine ribonucleotide catabolic process GO:0009154 75 0.015
Human Mouse
regulation of synapse assembly GO:0051963 2 0.015
organonitrogen compound metabolic process GO:1901564 151 0.015
Human Mouse
positive regulation of cell development GO:0010720 6 0.015
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.015
Human Mouse
positive regulation of cell adhesion GO:0045785 1 0.015
gamete generation GO:0007276 461 0.015
regulation of hydrolase activity GO:0051336 45 0.015
Human Mouse
regulation of nucleotide catabolic process GO:0030811 35 0.015
Human Mouse
regulation of ras protein signal transduction GO:0046578 41 0.015
positive regulation of growth GO:0045927 369 0.014
defense response to bacterium GO:0042742 86 0.014
regulation of signal transduction GO:0009966 135 0.014
epidermis development GO:0008544 24 0.014
excretion GO:0007588 49 0.014
regulation of signaling GO:0023051 172 0.014
striated muscle cell differentiation GO:0051146 158 0.014
positive chemotaxis GO:0050918 3 0.014
feeding behavior GO:0007631 70 0.014
ribonucleoside metabolic process GO:0009119 98 0.014
Human Mouse
regulation of cellular localization GO:0060341 42 0.014
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 72 0.014
Human Mouse
protein localization to membrane GO:0072657 11 0.014
actin cytoskeleton reorganization GO:0031532 4 0.014
actin cytoskeleton organization GO:0030036 184 0.014
positive regulation of cdc42 gtpase activity GO:0043089 3 0.014
organelle fission GO:0048285 363 0.014
regulation of cell morphogenesis GO:0022604 40 0.014
Human
regeneration GO:0031099 4 0.014
regulation of canonical wnt signaling pathway GO:0060828 1 0.013
Human
protein polymerization GO:0051258 26 0.013
positive regulation of cellular catabolic process GO:0031331 35 0.013
Human
single organism organelle organization GO:1902589 501 0.013
regulation of gtp catabolic process GO:0033124 32 0.013
Human Mouse
purine nucleoside triphosphate catabolic process GO:0009146 72 0.013
Human Mouse
glycosyl compound metabolic process GO:1901657 100 0.013
Human Mouse
negative regulation of protein metabolic process GO:0051248 27 0.013
Human Mouse
negative regulation of cellular process GO:0048523 239 0.013
actomyosin structure organization GO:0031032 154 0.013
positive regulation of rna metabolic process GO:0051254 103 0.013
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
defense response to other organism GO:0098542 100 0.013
positive regulation of cell communication GO:0010647 69 0.013
Human Mouse
cellular macromolecular complex assembly GO:0034622 184 0.013
female gamete generation GO:0007292 254 0.013
actin filament based process GO:0030029 191 0.013
formation of anatomical boundary GO:0048859 1 0.013
ribonucleoprotein complex assembly GO:0022618 4 0.013
purine nucleotide catabolic process GO:0006195 75 0.013
Human Mouse
positive regulation of protein transport GO:0051222 4 0.013
microtubule polymerization or depolymerization GO:0031109 22 0.013
protein oligomerization GO:0051259 4 0.013
macromolecular complex subunit organization GO:0043933 320 0.013
Human Mouse
hormone secretion GO:0046879 2 0.013
regulation of protein serine threonine kinase activity GO:0071900 18 0.013
Human Mouse
actin filament bundle assembly GO:0051017 3 0.013
carboxylic acid metabolic process GO:0019752 34 0.013
positive regulation of synapse assembly GO:0051965 1 0.013
growth GO:0040007 562 0.013
cellular biosynthetic process GO:0044249 315 0.012
Human
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.012
negative regulation of cell communication GO:0010648 61 0.012
aromatic compound catabolic process GO:0019439 116 0.012
Human Mouse
cell maturation GO:0048469 26 0.012
regulation of protein targeting GO:1903533 3 0.012
Mouse
response to bacterium GO:0009617 86 0.012
Human Mouse
neuron projection guidance GO:0097485 82 0.012
canonical wnt signaling pathway GO:0060070 3 0.012
Human
amine metabolic process GO:0009308 15 0.012
regulation of cell size GO:0008361 30 0.012
response to heat GO:0009408 50 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.012
Human Mouse
regulation of apoptotic signaling pathway GO:2001233 1 0.012
Human
myosin filament organization GO:0031033 138 0.012
dauer larval development GO:0040024 92 0.012
cell proliferation GO:0008283 116 0.012
Human Mouse
positive regulation of protein modification process GO:0031401 29 0.012
Human Mouse
microtubule based process GO:0007017 182 0.012
gene silencing GO:0016458 143 0.012
gene silencing by rna GO:0031047 143 0.012
homeostatic process GO:0042592 51 0.012
single organism behavior GO:0044708 83 0.012
nitrogen compound transport GO:0071705 49 0.012
organic substance biosynthetic process GO:1901576 323 0.012
Human
regulation of post embryonic development GO:0048580 260 0.012
cell cycle GO:0007049 526 0.012
Human
carbohydrate derivative catabolic process GO:1901136 82 0.012
Human Mouse
positive regulation of phosphorylation GO:0042327 27 0.012
Human Mouse
male anatomical structure morphogenesis GO:0090598 78 0.012
positive regulation of signaling GO:0023056 66 0.012
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.012
Human
regulation of filopodium assembly GO:0051489 2 0.011
regulation of organelle organization GO:0033043 164 0.011
single organism membrane organization GO:0044802 35 0.011
defense response to fungus GO:0050832 19 0.011
nucleotide catabolic process GO:0009166 77 0.011
Human Mouse
regulation of cytoplasmic transport GO:1903649 3 0.011
Mouse
purine containing compound metabolic process GO:0072521 95 0.011
Human Mouse
body morphogenesis GO:0010171 620 0.011
regulation of cytoskeleton organization GO:0051493 41 0.011
macromolecular complex assembly GO:0065003 193 0.011
Human Mouse
regulation of secretion GO:0051046 29 0.011
regulation of cell proliferation GO:0042127 105 0.011
Human Mouse
developmental cell growth GO:0048588 39 0.011
heterocycle biosynthetic process GO:0018130 187 0.011
Human
rna biosynthetic process GO:0032774 169 0.011
Human
positive regulation of axonogenesis GO:0050772 4 0.011
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.011
Human
sensory organ morphogenesis GO:0090596 2 0.011
negative regulation of response to external stimulus GO:0032102 3 0.011
organelle localization GO:0051640 127 0.011
immune response GO:0006955 192 0.010
nucleus localization GO:0051647 55 0.010
ribonucleotide metabolic process GO:0009259 99 0.010
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 102 0.010
Human
actin filament based movement GO:0030048 4 0.010
regulation of transport GO:0051049 91 0.010
Mouse
endomembrane system organization GO:0010256 22 0.010
positive regulation of transcription dna templated GO:0045893 102 0.010
Human
establishment of organelle localization GO:0051656 123 0.010
oxoacid metabolic process GO:0043436 47 0.010
regulation of reproductive process GO:2000241 66 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.010
response to oxidative stress GO:0006979 42 0.010

gap-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
disease of anatomical entity DOID:7 0 0.013
gastrointestinal system cancer DOID:3119 0 0.011