Caenorhabditis elegans

16 known processes

pyk-1 (CELE_F25H5.3)

Protein PYK-1

pyk-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multi organism reproductive process GO:0044703 867 0.403
multicellular organism reproduction GO:0032504 819 0.382
reproductive structure development GO:0048608 850 0.353
developmental process involved in reproduction GO:0003006 1165 0.338
single organism reproductive process GO:0044702 1196 0.310
locomotion GO:0040011 1634 0.270
single organism transport GO:0044765 447 0.235
establishment of localization GO:0051234 1171 0.234
organ development GO:0048513 1102 0.228
transport GO:0006810 1093 0.222
single organism localization GO:1902578 518 0.212
embryo development ending in birth or egg hatching GO:0009792 2992 0.191
organelle organization GO:0006996 783 0.188
Worm
gonad development GO:0008406 840 0.176
macromolecular complex subunit organization GO:0043933 320 0.164
Worm
gamete generation GO:0007276 461 0.150
regulation of multicellular organismal process GO:0051239 726 0.150
female gamete generation GO:0007292 254 0.145
behavior GO:0007610 527 0.144
embryo development GO:0009790 3052 0.137
multicellular organismal reproductive process GO:0048609 815 0.137
death GO:0016265 547 0.130
Human
cellular component biogenesis GO:0044085 297 0.124
Worm
multicellular organismal reproductive behavior GO:0033057 384 0.124
vesicle mediated transport GO:0016192 852 0.121
cellular localization GO:0051641 360 0.118
aging GO:0007568 812 0.116
endocytosis GO:0006897 819 0.113
regulation of biological quality GO:0065008 741 0.111
molting cycle GO:0042303 281 0.111
hermaphrodite genitalia development GO:0040035 734 0.105
macromolecule localization GO:0033036 771 0.102
single organism organelle organization GO:1902589 501 0.102
Worm
determination of adult lifespan GO:0008340 812 0.100
macromolecule catabolic process GO:0009057 202 0.097
reproductive behavior GO:0019098 387 0.095
signal transduction GO:0007165 317 0.092
multicellular organismal aging GO:0010259 812 0.091
catabolic process GO:0009056 318 0.091
Mouse
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.090
cell development GO:0048468 696 0.090
Worm
sexual reproduction GO:0019953 546 0.086
post embryonic development GO:0009791 2152 0.083
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.081
regulation of metabolic process GO:0019222 478 0.080
single organism signaling GO:0044700 401 0.079
cellular component assembly GO:0022607 293 0.079
Worm
regulation of macromolecule metabolic process GO:0060255 421 0.076
reproductive system development GO:0061458 850 0.075
protein metabolic process GO:0019538 422 0.075
multi organism behavior GO:0051705 389 0.074
organic substance biosynthetic process GO:1901576 323 0.073
establishment of localization in cell GO:0051649 318 0.073
cytoskeleton organization GO:0007010 339 0.069
Worm
oviposition GO:0018991 364 0.069
nucleobase containing compound metabolic process GO:0006139 406 0.069
positive regulation of developmental process GO:0051094 408 0.069
multi organism reproductive behavior GO:0044705 387 0.068
germ cell development GO:0007281 351 0.068
cell death GO:0008219 547 0.068
Human
cell cycle process GO:0022402 482 0.066
body morphogenesis GO:0010171 620 0.066
cellular component assembly involved in morphogenesis GO:0010927 183 0.065
Worm
sex differentiation GO:0007548 909 0.064
receptor mediated endocytosis GO:0006898 715 0.063
multi multicellular organism process GO:0044706 390 0.062
organic substance catabolic process GO:1901575 294 0.062
Mouse
lipid storage GO:0019915 565 0.060
programmed cell death GO:0012501 500 0.060
Human
regulation of multicellular organism growth GO:0040014 373 0.059
cell cycle GO:0007049 526 0.059
regulation of gene expression GO:0010468 366 0.058
maintenance of location GO:0051235 580 0.058
regulation of localization GO:0032879 194 0.058
regulation of growth GO:0040008 409 0.057
regulation of transport GO:0051049 91 0.057
signaling GO:0023052 401 0.056
cellular component movement GO:0006928 388 0.055
neuron differentiation GO:0030182 217 0.054
lipid localization GO:0010876 573 0.054
response to external stimulus GO:0009605 289 0.053
Mouse
cellular component morphogenesis GO:0032989 318 0.052
Worm
secretion GO:0046903 147 0.052
oogenesis GO:0048477 229 0.052
secretion by cell GO:0032940 138 0.051
regulation of developmental growth GO:0048638 389 0.050
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.050
head development GO:0060322 1 0.050
regulation of cellular component organization GO:0051128 248 0.049
regulation of developmental process GO:0050793 684 0.048
developmental growth GO:0048589 412 0.048
regulation of response to stimulus GO:0048583 243 0.047
cell migration GO:0016477 306 0.046
muscle cell differentiation GO:0042692 171 0.046
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.045
development of primary sexual characteristics GO:0045137 840 0.044
positive regulation of growth GO:0045927 369 0.043
organelle localization GO:0051640 127 0.042
multicellular organism growth GO:0035264 385 0.042
biosynthetic process GO:0009058 323 0.042
cellular catabolic process GO:0044248 199 0.040
membrane organization GO:0061024 135 0.040
growth GO:0040007 562 0.040
organonitrogen compound metabolic process GO:1901564 151 0.039
ion transmembrane transport GO:0034220 91 0.039
spindle organization GO:0007051 92 0.039
apoptotic process GO:0006915 478 0.039
nucleobase containing compound biosynthetic process GO:0034654 184 0.038
macromolecular complex assembly GO:0065003 193 0.038
Worm
cell projection assembly GO:0030031 35 0.037
posttranscriptional gene silencing GO:0016441 143 0.037
cell morphogenesis involved in differentiation GO:0000904 112 0.037
striated muscle cell differentiation GO:0051146 158 0.037
Worm
genitalia development GO:0048806 741 0.036
meiotic nuclear division GO:0007126 300 0.036
fertilization GO:0009566 63 0.035
muscle structure development GO:0061061 191 0.035
Worm
microtubule based process GO:0007017 182 0.034
establishment of organelle localization GO:0051656 123 0.034
posttranscriptional regulation of gene expression GO:0010608 166 0.034
protein catabolic process GO:0030163 162 0.034
negative regulation of biological process GO:0048519 567 0.034
small molecule metabolic process GO:0044281 186 0.033
Mouse
positive regulation of developmental growth GO:0048639 354 0.033
phosphorus metabolic process GO:0006793 232 0.032
Mouse
positive regulation of response to stimulus GO:0048584 55 0.032
regulation of gene expression epigenetic GO:0040029 163 0.032
apoptotic cell clearance GO:0043277 111 0.032
response to wounding GO:0009611 4 0.032
cell projection organization GO:0030030 231 0.032
protein complex biogenesis GO:0070271 186 0.032
Worm
positive regulation of multicellular organism growth GO:0040018 352 0.032
actin filament based process GO:0030029 191 0.031
Worm
oocyte construction GO:0007308 2 0.031
posttranscriptional gene silencing by rna GO:0035194 143 0.031
cellular biosynthetic process GO:0044249 315 0.031
heterocycle biosynthetic process GO:0018130 187 0.029
protein complex subunit organization GO:0071822 280 0.028
Worm
cation transmembrane transport GO:0098655 59 0.028
actomyosin structure organization GO:0031032 154 0.028
Worm
gene expression GO:0010467 412 0.027
transmembrane transport GO:0055085 110 0.027
organelle fission GO:0048285 363 0.027
cell motility GO:0048870 313 0.026
g protein coupled receptor signaling pathway GO:0007186 46 0.026
proteolysis GO:0006508 61 0.026
meiotic cell cycle GO:0051321 335 0.026
positive regulation of signaling GO:0023056 66 0.025
rna interference GO:0016246 137 0.025
protein localization GO:0008104 205 0.025
striated muscle cell development GO:0055002 157 0.025
Worm
muscle cell development GO:0055001 158 0.025
Worm
localization of cell GO:0051674 313 0.025
gene silencing GO:0016458 143 0.025
purine containing compound metabolic process GO:0072521 95 0.024
regulation of cell communication GO:0010646 176 0.024
tissue development GO:0009888 112 0.024
defense response GO:0006952 296 0.024
cation transport GO:0006812 78 0.024
positive regulation of cellular process GO:0048522 332 0.024
muscle tissue development GO:0060537 1 0.024
protein complex assembly GO:0006461 186 0.023
Worm
positive regulation of transport GO:0051050 32 0.023
mating GO:0007618 34 0.023
macromolecule modification GO:0043412 218 0.023
system process GO:0003008 136 0.023
gene silencing by rna GO:0031047 143 0.023
actin cytoskeleton organization GO:0030036 184 0.023
Worm
regulation of signaling GO:0023051 172 0.022
oxoacid metabolic process GO:0043436 47 0.022
Mouse
regulation of multi organism process GO:0043900 69 0.022
meiotic cell cycle process GO:1903046 170 0.022
axonogenesis GO:0007409 102 0.022
regulation of multicellular organismal development GO:2000026 317 0.021
myofibril assembly GO:0030239 154 0.021
Worm
regeneration GO:0031099 4 0.021
anatomical structure formation involved in morphogenesis GO:0048646 250 0.021
Worm
organelle assembly GO:0070925 214 0.021
Worm
cellular protein metabolic process GO:0044267 279 0.021
post embryonic organ development GO:0048569 336 0.021
nitrogen compound transport GO:0071705 49 0.021
ion transport GO:0006811 113 0.020
carbohydrate derivative metabolic process GO:1901135 141 0.020
positive regulation of cell communication GO:0010647 69 0.020
oocyte development GO:0048599 44 0.019
pronuclear migration GO:0035046 51 0.019
response to abiotic stimulus GO:0009628 152 0.019
neurological system process GO:0050877 53 0.019
regulation of organelle organization GO:0033043 164 0.018
nucleotide metabolic process GO:0009117 108 0.018
phagocytosis engulfment GO:0006911 98 0.018
chromosome organization GO:0051276 104 0.018
ovulation GO:0030728 33 0.018
taxis GO:0042330 128 0.018
chromosome segregation GO:0007059 180 0.018
aromatic compound biosynthetic process GO:0019438 192 0.018
digestive tract development GO:0048565 122 0.017
organophosphate metabolic process GO:0019637 125 0.017
chemotaxis GO:0006935 120 0.017
homeostatic process GO:0042592 51 0.017
rna localization GO:0006403 3 0.017
establishment or maintenance of cell polarity GO:0007163 63 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.017
single fertilization GO:0007338 61 0.017
neuron projection development GO:0031175 187 0.017
negative regulation of post embryonic development GO:0048581 208 0.017
cellular macromolecule localization GO:0070727 75 0.017
cell division GO:0051301 262 0.017
myosin filament organization GO:0031033 138 0.016
Worm
neuron projection guidance GO:0097485 82 0.016
mitotic cell cycle process GO:1903047 194 0.016
inorganic cation transmembrane transport GO:0098662 46 0.016
positive regulation of intracellular transport GO:0032388 2 0.016
engulfment of apoptotic cell GO:0043652 94 0.016
digestive system development GO:0055123 122 0.016
phagocytosis GO:0006909 115 0.016
regulation of oviposition GO:0046662 43 0.016
myosin filament assembly GO:0031034 138 0.016
Worm
protein oligomerization GO:0051259 4 0.016
establishment of nucleus localization GO:0040023 55 0.016
organic substance transport GO:0071702 113 0.015
regulation of ion transport GO:0043269 39 0.015
single organism behavior GO:0044708 83 0.015
anatomical structure homeostasis GO:0060249 11 0.015
embryonic morphogenesis GO:0048598 152 0.015
nucleobase containing small molecule metabolic process GO:0055086 115 0.015
regulation of cytoplasmic transport GO:1903649 3 0.015
detection of external stimulus GO:0009581 4 0.015
membrane invagination GO:0010324 98 0.015
cell projection morphogenesis GO:0048858 148 0.015
protein modification process GO:0036211 207 0.015
regulation of reproductive process GO:2000241 66 0.015
cell surface receptor signaling pathway GO:0007166 149 0.015
regulation of locomotion GO:0040012 161 0.015
nucleus localization GO:0051647 55 0.015
regulation of vulval development GO:0040028 248 0.014
positive regulation of intracellular signal transduction GO:1902533 24 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.014
carbohydrate derivative biosynthetic process GO:1901137 46 0.014
hormone transport GO:0009914 2 0.014
cell morphogenesis GO:0000902 163 0.014
positive regulation of signal transduction GO:0009967 40 0.014
inorganic ion transmembrane transport GO:0098660 54 0.014
regulation of behavior GO:0050795 97 0.014
response to chemical GO:0042221 356 0.014
establishment of protein localization to membrane GO:0090150 3 0.014
skeletal muscle organ development GO:0060538 3 0.014
regulation of post embryonic development GO:0048580 260 0.013
organonitrogen compound biosynthetic process GO:1901566 44 0.013
neuron projection morphogenesis GO:0048812 114 0.013
phosphate containing compound metabolic process GO:0006796 232 0.013
Mouse
negative regulation of cellular process GO:0048523 239 0.013
generation of neurons GO:0048699 235 0.013
rna metabolic process GO:0016070 228 0.013
nuclear migration GO:0007097 54 0.013
cell part morphogenesis GO:0032990 152 0.013
cellular nitrogen compound biosynthetic process GO:0044271 192 0.013
lipid metabolic process GO:0006629 77 0.012
tissue morphogenesis GO:0048729 65 0.012
axon guidance GO:0007411 82 0.012
organic cyclic compound biosynthetic process GO:1901362 195 0.012
cellular response to stress GO:0033554 162 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
Mouse
positive regulation of neurogenesis GO:0050769 4 0.012
nucleoside phosphate metabolic process GO:0006753 108 0.012
negative regulation of vulval development GO:0040027 206 0.012
negative regulation of nematode larval development GO:0061064 208 0.012
regulation of protein stability GO:0031647 3 0.011
intracellular signal transduction GO:0035556 96 0.011
vulval development GO:0040025 333 0.011
neuron development GO:0048666 199 0.011
regulation of nematode larval development GO:0061062 260 0.011
negative regulation of multicellular organismal process GO:0051241 236 0.011
positive regulation of protein transport GO:0051222 4 0.011
nucleoside metabolic process GO:0009116 99 0.011
cellular protein complex assembly GO:0043623 178 0.011
Worm
cell proliferation GO:0008283 116 0.011
macromolecule biosynthetic process GO:0009059 250 0.011
negative regulation of metabolic process GO:0009892 240 0.011
regulation of cellular localization GO:0060341 42 0.011
muscle contraction GO:0006936 43 0.011
pharyngeal pumping GO:0043050 58 0.011
cell adhesion GO:0007155 21 0.011
regulation of signal transduction GO:0009966 135 0.011
muscle system process GO:0003012 43 0.011
glycosyl compound catabolic process GO:1901658 79 0.011
mitotic spindle organization GO:0007052 81 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.010
negative regulation of signaling GO:0023057 61 0.010
mitotic nuclear division GO:0007067 89 0.010
cellular protein localization GO:0034613 75 0.010
feeding behavior GO:0007631 70 0.010
regulation of hormone secretion GO:0046883 2 0.010
nervous system development GO:0007399 253 0.010
organic acid metabolic process GO:0006082 47 0.010
Mouse
epithelial cell proliferation GO:0050673 1 0.010

pyk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
disease of metabolism DOID:0014667 0 0.012
nervous system disease DOID:863 0 0.012
musculoskeletal system disease DOID:17 0 0.011