Caenorhabditis elegans

98 known processes

lon-2 (CELE_C39E6.1)

Protein LON-2

lon-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.593
embryo development ending in birth or egg hatching GO:0009792 2992 0.478
embryo development GO:0009790 3052 0.419
locomotion GO:0040011 1634 0.288
multi organism reproductive process GO:0044703 867 0.240
phosphate containing compound metabolic process GO:0006796 232 0.219
phosphorus metabolic process GO:0006793 232 0.203
innate immune response GO:0045087 190 0.184
defense response GO:0006952 296 0.182
organelle organization GO:0006996 783 0.167
regulation of multicellular organismal process GO:0051239 726 0.154
multicellular organismal reproductive process GO:0048609 815 0.153
negative regulation of biological process GO:0048519 567 0.141
behavior GO:0007610 527 0.137
vulval development GO:0040025 333 0.135
positive regulation of multicellular organismal process GO:0051240 417 0.133
multicellular organism reproduction GO:0032504 819 0.132
multi organism reproductive behavior GO:0044705 387 0.129
positive regulation of metabolic process GO:0009893 187 0.126
nervous system development GO:0007399 253 0.126
organophosphate catabolic process GO:0046434 81 0.123
response to external stimulus GO:0009605 289 0.123
organophosphate metabolic process GO:0019637 125 0.121
multi organism behavior GO:0051705 389 0.120
catabolic process GO:0009056 318 0.120
response to abiotic stimulus GO:0009628 152 0.117
regulation of biological quality GO:0065008 741 0.114
single organism signaling GO:0044700 401 0.112
sexual reproduction GO:0019953 546 0.112
meiotic cell cycle process GO:1903046 170 0.108
determination of adult lifespan GO:0008340 812 0.108
single organism reproductive process GO:0044702 1196 0.105
regulation of metabolic process GO:0019222 478 0.105
growth GO:0040007 562 0.105
signaling GO:0023052 401 0.102
nucleobase containing compound metabolic process GO:0006139 406 0.102
macromolecule localization GO:0033036 771 0.100
multicellular organismal aging GO:0010259 812 0.099
meiotic cell cycle GO:0051321 335 0.096
cellular component morphogenesis GO:0032989 318 0.094
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.094
death GO:0016265 547 0.093
negative regulation of vulval development GO:0040027 206 0.091
meiotic chromosome segregation GO:0045132 139 0.088
organic substance catabolic process GO:1901575 294 0.086
cell morphogenesis GO:0000902 163 0.084
post embryonic organ development GO:0048569 336 0.084
aging GO:0007568 812 0.083
carbohydrate derivative catabolic process GO:1901136 82 0.083
cell cycle process GO:0022402 482 0.082
body morphogenesis GO:0010171 620 0.082
mating behavior GO:0007617 32 0.081
response to chemical GO:0042221 356 0.081
signal transduction GO:0007165 317 0.081
cellular catabolic process GO:0044248 199 0.081
transport GO:0006810 1093 0.081
cell development GO:0048468 696 0.079
biosynthetic process GO:0009058 323 0.079
regulation of cellular component organization GO:0051128 248 0.079
nucleoside phosphate catabolic process GO:1901292 77 0.078
receptor mediated endocytosis GO:0006898 715 0.078
neuron development GO:0048666 199 0.078
gamete generation GO:0007276 461 0.077
regulation of multicellular organism growth GO:0040014 373 0.076
nucleoside metabolic process GO:0009116 99 0.076
organelle fission GO:0048285 363 0.076
organic substance biosynthetic process GO:1901576 323 0.074
single organism catabolic process GO:0044712 129 0.074
cellular component biogenesis GO:0044085 297 0.074
meiotic nuclear division GO:0007126 300 0.073
developmental process involved in reproduction GO:0003006 1165 0.072
organ development GO:0048513 1102 0.072
macromolecular complex subunit organization GO:0043933 320 0.071
neurotransmitter transport GO:0006836 32 0.070
germ cell development GO:0007281 351 0.068
lipid localization GO:0010876 573 0.067
positive regulation of developmental process GO:0051094 408 0.067
maintenance of location GO:0051235 580 0.067
chromosome segregation GO:0007059 180 0.067
regulation of vulval development GO:0040028 248 0.065
aromatic compound catabolic process GO:0019439 116 0.065
multicellular organism growth GO:0035264 385 0.064
regulation of locomotion GO:0040012 161 0.064
lipid storage GO:0019915 565 0.062
multicellular organismal reproductive behavior GO:0033057 384 0.060
regulation of cellular metabolic process GO:0031323 305 0.060
cation transport GO:0006812 78 0.060
regulation of localization GO:0032879 194 0.059
neuron differentiation GO:0030182 217 0.058
multi multicellular organism process GO:0044706 390 0.058
cellular component assembly GO:0022607 293 0.058
regulation of post embryonic development GO:0048580 260 0.058
cellular localization GO:0051641 360 0.058
organonitrogen compound catabolic process GO:1901565 90 0.058
positive regulation of cellular metabolic process GO:0031325 178 0.058
organelle assembly GO:0070925 214 0.057
regulation of developmental growth GO:0048638 389 0.057
establishment of localization GO:0051234 1171 0.056
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.055
purine ribonucleotide catabolic process GO:0009154 75 0.054
purine containing compound catabolic process GO:0072523 75 0.054
single organism transport GO:0044765 447 0.053
cell cycle GO:0007049 526 0.053
positive regulation of cellular process GO:0048522 332 0.052
cell motility GO:0048870 313 0.052
head development GO:0060322 1 0.051
organonitrogen compound metabolic process GO:1901564 151 0.051
positive regulation of growth GO:0045927 369 0.050
macromolecule modification GO:0043412 218 0.050
purine nucleoside catabolic process GO:0006152 75 0.050
developmental growth GO:0048589 412 0.049
oogenesis GO:0048477 229 0.049
cell cell signaling GO:0007267 118 0.049
secretion GO:0046903 147 0.049
cellular biosynthetic process GO:0044249 315 0.048
cell projection organization GO:0030030 231 0.048
oviposition GO:0018991 364 0.048
immune response GO:0006955 192 0.048
development of primary sexual characteristics GO:0045137 840 0.047
heterocycle biosynthetic process GO:0018130 187 0.047
regulation of gene expression GO:0010468 366 0.047
gene expression GO:0010467 412 0.046
small molecule metabolic process GO:0044281 186 0.046
purine nucleotide catabolic process GO:0006195 75 0.045
cellular protein modification process GO:0006464 207 0.045
purine nucleotide metabolic process GO:0006163 95 0.045
cellular response to topologically incorrect protein GO:0035967 76 0.045
response to topologically incorrect protein GO:0035966 82 0.045
regulation of nematode larval development GO:0061062 260 0.044
single organism localization GO:1902578 518 0.043
regulation of developmental process GO:0050793 684 0.043
synaptic transmission GO:0007268 106 0.043
nucleoside triphosphate catabolic process GO:0009143 72 0.043
reproductive behavior GO:0019098 387 0.042
purine nucleoside triphosphate metabolic process GO:0009144 87 0.042
ribonucleotide catabolic process GO:0009261 75 0.042
cell surface receptor signaling pathway GO:0007166 149 0.042
cellular component movement GO:0006928 388 0.042
protein complex biogenesis GO:0070271 186 0.042
negative regulation of nematode larval development GO:0061064 208 0.042
regulation of signaling GO:0023051 172 0.042
purine ribonucleotide metabolic process GO:0009150 95 0.041
positive regulation of cell communication GO:0010647 69 0.040
regulation of growth GO:0040008 409 0.040
nucleoside phosphate metabolic process GO:0006753 108 0.040
ribonucleoside catabolic process GO:0042454 77 0.039
regulation of protein metabolic process GO:0051246 81 0.039
guanosine containing compound metabolic process GO:1901068 49 0.039
organic cyclic compound catabolic process GO:1901361 119 0.039
nucleobase containing small molecule metabolic process GO:0055086 115 0.038
ribose phosphate metabolic process GO:0019693 99 0.038
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.038
positive regulation of multicellular organism growth GO:0040018 352 0.037
cellular macromolecular complex assembly GO:0034622 184 0.037
female gamete generation GO:0007292 254 0.037
cellular response to unfolded protein GO:0034620 71 0.037
muscle structure development GO:0061061 191 0.036
heterocycle catabolic process GO:0046700 119 0.036
regulation of neurotransmitter levels GO:0001505 36 0.036
negative regulation of macromolecule metabolic process GO:0010605 229 0.035
sex differentiation GO:0007548 909 0.035
carbohydrate derivative metabolic process GO:1901135 141 0.035
cellular response to stress GO:0033554 162 0.035
system process GO:0003008 136 0.035
glycosyl compound catabolic process GO:1901658 79 0.034
ribonucleoside metabolic process GO:0009119 98 0.034
negative regulation of metabolic process GO:0009892 240 0.034
regulation of catabolic process GO:0009894 57 0.034
dauer larval development GO:0040024 92 0.034
macromolecular complex assembly GO:0065003 193 0.034
actomyosin structure organization GO:0031032 154 0.034
purine nucleoside metabolic process GO:0042278 92 0.033
regulation of response to stimulus GO:0048583 243 0.033
positive regulation of cellular catabolic process GO:0031331 35 0.033
defense response to other organism GO:0098542 100 0.033
posttranscriptional regulation of gene expression GO:0010608 166 0.033
regulation of cell migration GO:0030334 55 0.033
positive regulation of developmental growth GO:0048639 354 0.032
purine ribonucleoside metabolic process GO:0046128 92 0.032
cell division GO:0051301 262 0.032
phosphorylation GO:0016310 116 0.032
nucleotide catabolic process GO:0009166 77 0.031
cellular nitrogen compound biosynthetic process GO:0044271 192 0.031
neuron projection development GO:0031175 187 0.031
endocytosis GO:0006897 819 0.031
amine metabolic process GO:0009308 15 0.031
nucleobase containing compound catabolic process GO:0034655 114 0.031
response to other organism GO:0051707 101 0.031
purine nucleoside triphosphate catabolic process GO:0009146 72 0.031
regulation of phosphate metabolic process GO:0019220 81 0.031
protein metabolic process GO:0019538 422 0.030
positive regulation of catabolic process GO:0009896 38 0.030
nucleobase containing compound biosynthetic process GO:0034654 184 0.030
secretion by cell GO:0032940 138 0.030
regulation of cell division GO:0051302 142 0.030
regulation of gene expression epigenetic GO:0040029 163 0.030
regulation of cell cycle GO:0051726 194 0.030
protein complex subunit organization GO:0071822 280 0.030
cellular amine metabolic process GO:0044106 15 0.030
aromatic compound biosynthetic process GO:0019438 192 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.029
localization of cell GO:0051674 313 0.029
p38mapk cascade GO:0038066 2 0.029
transcription from rna polymerase ii promoter GO:0006366 149 0.029
single organism organelle organization GO:1902589 501 0.029
programmed cell death GO:0012501 500 0.029
cellular nitrogen compound catabolic process GO:0044270 119 0.029
purine containing compound metabolic process GO:0072521 95 0.028
reproductive structure development GO:0048608 850 0.028
guanosine containing compound catabolic process GO:1901069 48 0.028
cellular response to organic substance GO:0071310 119 0.028
cell migration GO:0016477 306 0.028
response to wounding GO:0009611 4 0.028
gene silencing GO:0016458 143 0.028
regulation of synapse assembly GO:0051963 2 0.028
cellular protein metabolic process GO:0044267 279 0.027
cytoskeleton organization GO:0007010 339 0.027
reproductive system development GO:0061458 850 0.027
regulation of cellular biosynthetic process GO:0031326 189 0.027
regulation of response to wounding GO:1903034 1 0.027
cellular macromolecule biosynthetic process GO:0034645 247 0.027
regulation of macromolecule metabolic process GO:0060255 421 0.026
single organism behavior GO:0044708 83 0.026
response to biotic stimulus GO:0009607 101 0.026
negative regulation of developmental process GO:0051093 227 0.026
purine ribonucleoside catabolic process GO:0046130 75 0.026
taxis GO:0042330 128 0.026
gene silencing by rna GO:0031047 143 0.025
regulation of biosynthetic process GO:0009889 189 0.025
generation of neurons GO:0048699 235 0.025
apoptotic process GO:0006915 478 0.025
hermaphrodite genitalia development GO:0040035 734 0.025
nucleotide metabolic process GO:0009117 108 0.025
nucleic acid metabolic process GO:0090304 299 0.025
mitotic nuclear division GO:0007067 89 0.024
response to organic substance GO:0010033 131 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.024
cell projection morphogenesis GO:0048858 148 0.024
ribonucleoside triphosphate catabolic process GO:0009203 72 0.024
posttranscriptional gene silencing by rna GO:0035194 143 0.024
regulation of secretion GO:0051046 29 0.024
macromolecule biosynthetic process GO:0009059 250 0.024
regulation of filopodium assembly GO:0051489 2 0.024
protein modification process GO:0036211 207 0.024
regulation of phosphorus metabolic process GO:0051174 81 0.024
metal ion transport GO:0030001 49 0.023
positive regulation of secretion GO:0051047 17 0.023
regulation of cell motility GO:2000145 57 0.023
protein complex assembly GO:0006461 186 0.023
rna interference GO:0016246 137 0.023
homeostatic process GO:0042592 51 0.023
regulation of transport GO:0051049 91 0.023
cell death GO:0008219 547 0.023
myofibril assembly GO:0030239 154 0.022
macromolecule catabolic process GO:0009057 202 0.022
posttranscriptional gene silencing GO:0016441 143 0.022
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.021
collagen and cuticulin based cuticle development GO:0040002 99 0.021
glycosyl compound metabolic process GO:1901657 100 0.021
cellular response to abiotic stimulus GO:0071214 4 0.021
actin filament based process GO:0030029 191 0.021
response to unfolded protein GO:0006986 71 0.021
single organism biosynthetic process GO:0044711 91 0.021
protein catabolic process GO:0030163 162 0.020
protein localization GO:0008104 205 0.020
cellular response to nutrient levels GO:0031669 13 0.020
regulation of organelle organization GO:0033043 164 0.020
positive regulation of signaling GO:0023056 66 0.020
nucleoside catabolic process GO:0009164 78 0.020
regulation of primary metabolic process GO:0080090 292 0.020
g protein coupled receptor signaling pathway GO:0007186 46 0.020
regulation of nuclear division GO:0051783 115 0.020
nucleoside monophosphate metabolic process GO:0009123 46 0.020
intracellular receptor signaling pathway GO:0030522 2 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
cellular amino acid metabolic process GO:0006520 15 0.019
neuron projection morphogenesis GO:0048812 114 0.019
cellular protein complex assembly GO:0043623 178 0.019
positive regulation of nematode larval development GO:0061063 54 0.019
negative regulation of post embryonic development GO:0048581 208 0.019
negative regulation of gene expression GO:0010629 217 0.019
negative regulation of cellular process GO:0048523 239 0.019
genitalia development GO:0048806 741 0.019
skeletal muscle organ development GO:0060538 3 0.019
gtp catabolic process GO:0006184 46 0.019
actin cytoskeleton organization GO:0030036 184 0.019
regulation of cellular catabolic process GO:0031329 51 0.019
regulation of signal transduction GO:0009966 135 0.018
regulation of macromolecule biosynthetic process GO:0010556 189 0.018
rna metabolic process GO:0016070 228 0.018
phagocytosis engulfment GO:0006911 98 0.018
striated muscle cell differentiation GO:0051146 158 0.018
ribonucleotide metabolic process GO:0009259 99 0.018
regulation of synaptic transmission GO:0050804 34 0.018
engulfment of apoptotic cell GO:0043652 94 0.018
myosin filament organization GO:0031033 138 0.017
regulation of cell communication GO:0010646 176 0.017
chemotaxis GO:0006935 120 0.017
regulation of cell cycle process GO:0010564 145 0.017
regulation of cellular protein metabolic process GO:0032268 75 0.017
positive regulation of intracellular transport GO:0032388 2 0.017
vesicle mediated transport GO:0016192 852 0.017
regulation of nucleocytoplasmic transport GO:0046822 3 0.017
organic cyclic compound biosynthetic process GO:1901362 195 0.017
molting cycle GO:0042303 281 0.017
detection of external stimulus GO:0009581 4 0.017
ion transport GO:0006811 113 0.017
inductive cell migration GO:0040039 145 0.017
nucleic acid templated transcription GO:0097659 169 0.017
neurogenesis GO:0022008 236 0.017
response to transition metal nanoparticle GO:1990267 18 0.017
apoptotic cell clearance GO:0043277 111 0.017
organonitrogen compound biosynthetic process GO:1901566 44 0.017
cell part morphogenesis GO:0032990 152 0.017
neuron projection guidance GO:0097485 82 0.016
response to temperature stimulus GO:0009266 66 0.016
nucleoside triphosphate metabolic process GO:0009141 87 0.016
autophagy GO:0006914 29 0.016
defense response to bacterium GO:0042742 86 0.016
positive regulation of locomotion GO:0040017 42 0.016
negative regulation of signal transduction GO:0009968 60 0.016
response to oxygen containing compound GO:1901700 44 0.016
response to extracellular stimulus GO:0009991 38 0.015
small gtpase mediated signal transduction GO:0007264 32 0.015
signal release GO:0023061 28 0.015
regulation of multicellular organismal development GO:2000026 317 0.015
pigment metabolic process GO:0042440 2 0.015
cell morphogenesis involved in differentiation GO:0000904 112 0.015
lipid metabolic process GO:0006629 77 0.015
mitotic cell cycle process GO:1903047 194 0.015
positive regulation of molecular function GO:0044093 61 0.015
regulation of nitrogen compound metabolic process GO:0051171 222 0.015
gonad development GO:0008406 840 0.014
er nucleus signaling pathway GO:0006984 66 0.014
adult locomotory behavior GO:0008344 1 0.014
ribonucleoprotein complex assembly GO:0022618 4 0.014
striated muscle cell development GO:0055002 157 0.014
positive regulation of cell migration GO:0030335 3 0.014
regulation of neurotransmitter transport GO:0051588 16 0.014
spindle organization GO:0007051 92 0.014
response to starvation GO:0042594 26 0.014
ribonucleoside monophosphate metabolic process GO:0009161 45 0.014
response to external biotic stimulus GO:0043207 101 0.014
myosin filament assembly GO:0031034 138 0.014
neurotransmitter secretion GO:0007269 26 0.014
positive regulation of protein metabolic process GO:0051247 45 0.014
establishment of localization in cell GO:0051649 318 0.014
organic substance transport GO:0071702 113 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
mitotic spindle organization GO:0007052 81 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.013
positive regulation of secretion by cell GO:1903532 14 0.013
cell proliferation GO:0008283 116 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
positive regulation of macromolecule metabolic process GO:0010604 149 0.013
intracellular signal transduction GO:0035556 96 0.013
regulation of protein targeting GO:1903533 3 0.013
translation GO:0006412 37 0.013
protein oligomerization GO:0051259 4 0.013
axon guidance GO:0007411 82 0.013
memory GO:0007613 3 0.013
negative regulation of multicellular organismal process GO:0051241 236 0.013
regulation of cellular localization GO:0060341 42 0.013
regulation of cytoplasmic transport GO:1903649 3 0.013
positive regulation of neurogenesis GO:0050769 4 0.013
positive regulation of phosphorus metabolic process GO:0010562 56 0.013
membrane invagination GO:0010324 98 0.013
regulation of organ morphogenesis GO:2000027 4 0.013
transmembrane transport GO:0055085 110 0.013
positive regulation of vulval development GO:0040026 52 0.013
positive regulation of cellular protein catabolic process GO:1903364 3 0.013
negative regulation of cell communication GO:0010648 61 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
positive regulation of protein transport GO:0051222 4 0.012
regulation of behavior GO:0050795 97 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.012
detection of abiotic stimulus GO:0009582 4 0.012
mating GO:0007618 34 0.012
regulation of transcription dna templated GO:0006355 164 0.012
negative regulation of gene expression epigenetic GO:0045814 2 0.012
regulation of protein import into nucleus GO:0042306 3 0.012
translational initiation GO:0006413 2 0.012
single organism carbohydrate metabolic process GO:0044723 29 0.012
copulation GO:0007620 2 0.012
positive regulation of rna biosynthetic process GO:1902680 102 0.012
regulation of ion transport GO:0043269 39 0.012
synaptic transmission cholinergic GO:0007271 21 0.012
negative regulation of response to stimulus GO:0048585 73 0.012
regulation of intracellular signal transduction GO:1902531 77 0.012
positive regulation of stem cell differentiation GO:2000738 1 0.012
gtp metabolic process GO:0046039 46 0.011
regulation of oviposition GO:0046662 43 0.011
negative regulation of cellular biosynthetic process GO:0031327 65 0.011
muscle cell differentiation GO:0042692 171 0.011
actin cytoskeleton reorganization GO:0031532 4 0.011
cellular protein localization GO:0034613 75 0.011
regulation of programmed cell death GO:0043067 50 0.011
response to endoplasmic reticulum stress GO:0034976 71 0.011
regulation of meiotic cell cycle GO:0051445 136 0.011
male mating behavior GO:0060179 26 0.011
asymmetric cell division GO:0008356 36 0.011
muscle tissue development GO:0060537 1 0.011
macroautophagy GO:0016236 11 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.011
response to nutrient levels GO:0031667 35 0.011
excretion GO:0007588 49 0.011
response to bacterium GO:0009617 86 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
acetate ester transport GO:1901374 16 0.011
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
sensory organ morphogenesis GO:0090596 2 0.011
regulation of hydrolase activity GO:0051336 45 0.011
protein phosphorylation GO:0006468 85 0.011
positive regulation of transport GO:0051050 32 0.011
ribonucleoside triphosphate metabolic process GO:0009199 87 0.010
adult behavior GO:0030534 3 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
carbohydrate metabolic process GO:0005975 34 0.010
single organism cellular localization GO:1902580 72 0.010
negative regulation of cellular metabolic process GO:0031324 95 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.010
negative regulation of biosynthetic process GO:0009890 65 0.010
cell type specific apoptotic process GO:0097285 4 0.010

lon-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
disease of metabolism DOID:0014667 0 0.014