Caenorhabditis elegans

10 known processes

his-60 (CELE_F55G1.11)

Protein HIS-60

his-60 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.283
embryo development ending in birth or egg hatching GO:0009792 2992 0.273
post embryonic development GO:0009791 2152 0.268
Worm
locomotion GO:0040011 1634 0.186
Worm
development of primary sexual characteristics GO:0045137 840 0.158
Worm
gonad development GO:0008406 840 0.155
Worm
single organism reproductive process GO:0044702 1196 0.145
Yeast Worm
reproductive structure development GO:0048608 850 0.140
Worm
reproductive system development GO:0061458 850 0.139
Worm
hermaphrodite genitalia development GO:0040035 734 0.137
Worm
organ development GO:0048513 1102 0.127
Worm
sex differentiation GO:0007548 909 0.123
Worm
multi organism reproductive process GO:0044703 867 0.121
Yeast
developmental process involved in reproduction GO:0003006 1165 0.120
Yeast Worm
genitalia development GO:0048806 741 0.109
Worm
aging GO:0007568 812 0.105
multicellular organism reproduction GO:0032504 819 0.102
multicellular organismal reproductive process GO:0048609 815 0.101
multicellular organismal aging GO:0010259 812 0.098
body morphogenesis GO:0010171 620 0.093
Worm
organelle organization GO:0006996 783 0.092
Yeast Worm
determination of adult lifespan GO:0008340 812 0.089
multicellular organismal reproductive behavior GO:0033057 384 0.086
multi organism reproductive behavior GO:0044705 387 0.085
oviposition GO:0018991 364 0.082
vesicle mediated transport GO:0016192 852 0.081
Worm
establishment of localization GO:0051234 1171 0.081
Worm
regulation of biological quality GO:0065008 741 0.076
Worm
receptor mediated endocytosis GO:0006898 715 0.075
Worm
macromolecule localization GO:0033036 771 0.073
Worm
behavior GO:0007610 527 0.071
transport GO:0006810 1093 0.071
Worm
negative regulation of biological process GO:0048519 567 0.070
Yeast
endocytosis GO:0006897 819 0.070
Worm
lipid localization GO:0010876 573 0.066
Worm
multi organism behavior GO:0051705 389 0.065
maintenance of location GO:0051235 580 0.063
Worm
multi multicellular organism process GO:0044706 390 0.062
lipid storage GO:0019915 565 0.062
Worm
regulation of primary metabolic process GO:0080090 292 0.060
Yeast Worm
sexual reproduction GO:0019953 546 0.060
Yeast
regulation of macromolecule metabolic process GO:0060255 421 0.059
Yeast Worm
cell cycle GO:0007049 526 0.059
Yeast
macromolecular complex subunit organization GO:0043933 320 0.057
Yeast Worm
tube development GO:0035295 126 0.057
Worm
regulation of multicellular organismal process GO:0051239 726 0.056
cell death GO:0008219 547 0.055
digestive system development GO:0055123 122 0.054
Worm
digestive tract development GO:0048565 122 0.054
Worm
reproductive behavior GO:0019098 387 0.053
organic substance biosynthetic process GO:1901576 323 0.052
Yeast Worm
regulation of metabolic process GO:0019222 478 0.052
Yeast Worm
single organism localization GO:1902578 518 0.051
Worm
transcription dna templated GO:0006351 168 0.050
Yeast Worm
nucleobase containing compound metabolic process GO:0006139 406 0.050
Yeast Worm
regulation of developmental process GO:0050793 684 0.050
death GO:0016265 547 0.049
biosynthetic process GO:0009058 323 0.049
Yeast Worm
head development GO:0060322 1 0.048
rna metabolic process GO:0016070 228 0.048
Yeast Worm
cell development GO:0048468 696 0.046
Worm
defense response GO:0006952 296 0.045
Worm
cellular biosynthetic process GO:0044249 315 0.044
Yeast Worm
negative regulation of macromolecule metabolic process GO:0010605 229 0.044
Yeast
gene expression GO:0010467 412 0.044
Yeast Worm
regulation of gene expression GO:0010468 366 0.044
Yeast Worm
programmed cell death GO:0012501 500 0.043
protein complex subunit organization GO:0071822 280 0.043
Worm
cellular macromolecule biosynthetic process GO:0034645 247 0.043
Yeast Worm
regulation of developmental growth GO:0048638 389 0.043
positive regulation of cellular process GO:0048522 332 0.042
Worm
multicellular organism growth GO:0035264 385 0.042
growth GO:0040007 562 0.042
cell cycle process GO:0022402 482 0.042
Yeast
negative regulation of gene expression epigenetic GO:0045814 2 0.041
Yeast
cellular component morphogenesis GO:0032989 318 0.041
Worm
macromolecule biosynthetic process GO:0009059 250 0.041
Yeast Worm
nucleic acid metabolic process GO:0090304 299 0.040
Yeast Worm
vulval development GO:0040025 333 0.040
cellular localization GO:0051641 360 0.040
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.040
single organism organelle organization GO:1902589 501 0.039
Yeast Worm
cellular nitrogen compound biosynthetic process GO:0044271 192 0.039
Yeast Worm
apoptotic process GO:0006915 478 0.039
negative regulation of gene expression GO:0010629 217 0.039
Yeast
organic cyclic compound biosynthetic process GO:1901362 195 0.039
Yeast Worm
positive regulation of growth GO:0045927 369 0.039
heterocycle biosynthetic process GO:0018130 187 0.039
Yeast Worm
regulation of multicellular organism growth GO:0040014 373 0.038
developmental growth GO:0048589 412 0.038
regulation of cellular metabolic process GO:0031323 305 0.038
Yeast Worm
pharynx development GO:0060465 51 0.038
Worm
regulation of growth GO:0040008 409 0.038
cellular component assembly GO:0022607 293 0.038
Worm
post embryonic organ development GO:0048569 336 0.038
positive regulation of developmental growth GO:0048639 354 0.037
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.037
Yeast Worm
organelle fission GO:0048285 363 0.037
positive regulation of multicellular organism growth GO:0040018 352 0.037
single organism transport GO:0044765 447 0.035
Worm
negative regulation of cellular process GO:0048523 239 0.035
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.035
Yeast Worm
negative regulation of metabolic process GO:0009892 240 0.035
Yeast
positive regulation of developmental process GO:0051094 408 0.034
rna biosynthetic process GO:0032774 169 0.034
Yeast Worm
nucleic acid templated transcription GO:0097659 169 0.034
Yeast Worm
cell division GO:0051301 262 0.034
protein metabolic process GO:0019538 422 0.033
Yeast
regulation of transcription dna templated GO:0006355 164 0.033
Yeast Worm
cellular component biogenesis GO:0044085 297 0.032
Worm
establishment of localization in cell GO:0051649 318 0.032
Worm
protein complex biogenesis GO:0070271 186 0.032
Worm
catabolic process GO:0009056 318 0.032
molting cycle GO:0042303 281 0.031
regulation of nematode larval development GO:0061062 260 0.031
immune response GO:0006955 192 0.031
cellular response to stress GO:0033554 162 0.031
nucleobase containing compound biosynthetic process GO:0034654 184 0.031
Yeast Worm
small molecule metabolic process GO:0044281 186 0.031
cytoskeleton organization GO:0007010 339 0.031
Worm
response to wounding GO:0009611 4 0.031
chromatin assembly or disassembly GO:0006333 1 0.031
regulation of multicellular organismal development GO:2000026 317 0.031
single organism signaling GO:0044700 401 0.030
transcription from rna polymerase ii promoter GO:0006366 149 0.030
Yeast Worm
regulation of nucleic acid templated transcription GO:1903506 165 0.029
Yeast Worm
cellular protein metabolic process GO:0044267 279 0.029
Yeast
aromatic compound biosynthetic process GO:0019438 192 0.029
Yeast Worm
regulation of post embryonic development GO:0048580 260 0.029
signal transduction GO:0007165 317 0.029
cellular component movement GO:0006928 388 0.029
meiotic cell cycle process GO:1903046 170 0.029
Yeast
response to chemical GO:0042221 356 0.029
localization of cell GO:0051674 313 0.029
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.029
Yeast Worm
regulation of macromolecule biosynthetic process GO:0010556 189 0.029
Yeast Worm
regulation of cellular biosynthetic process GO:0031326 189 0.029
Yeast Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.029
Yeast Worm
positive regulation of metabolic process GO:0009893 187 0.028
Worm
gamete generation GO:0007276 461 0.028
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.028
protein complex assembly GO:0006461 186 0.028
Worm
meiotic cell cycle GO:0051321 335 0.028
Yeast
negative regulation of multicellular organismal process GO:0051241 236 0.027
macromolecule modification GO:0043412 218 0.027
Yeast
negative regulation of nematode larval development GO:0061064 208 0.027
regulation of biosynthetic process GO:0009889 189 0.027
Yeast Worm
sensory organ morphogenesis GO:0090596 2 0.027
signaling GO:0023052 401 0.027
cellular protein complex assembly GO:0043623 178 0.027
Worm
regulation of cellular component organization GO:0051128 248 0.027
actin filament based process GO:0030029 191 0.026
Worm
organic substance catabolic process GO:1901575 294 0.026
cellular catabolic process GO:0044248 199 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.026
Yeast
regulation of rna biosynthetic process GO:2001141 165 0.026
Yeast Worm
regulation of gene expression epigenetic GO:0040029 163 0.026
Yeast
actin cytoskeleton organization GO:0030036 184 0.025
Worm
regulation of vulval development GO:0040028 248 0.025
negative regulation of developmental process GO:0051093 227 0.025
negative regulation of transcription dna templated GO:0045892 53 0.025
Yeast
regulation of rna metabolic process GO:0051252 173 0.025
Yeast Worm
negative regulation of post embryonic development GO:0048581 208 0.025
regulation of organelle organization GO:0033043 164 0.025
cell motility GO:0048870 313 0.025
anatomical structure formation involved in morphogenesis GO:0048646 250 0.025
Yeast Worm
meiotic nuclear division GO:0007126 300 0.024
organonitrogen compound metabolic process GO:1901564 151 0.024
negative regulation of nucleic acid templated transcription GO:1903507 53 0.023
Yeast
macromolecular complex assembly GO:0065003 193 0.023
Worm
cellular macromolecular complex assembly GO:0034622 184 0.023
Worm
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.023
regulation of localization GO:0032879 194 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.022
Yeast
secretion by cell GO:0032940 138 0.022
Worm
cell migration GO:0016477 306 0.022
mitotic cell cycle process GO:1903047 194 0.022
negative regulation of vulval development GO:0040027 206 0.022
microtubule based process GO:0007017 182 0.022
cellular response to dna damage stimulus GO:0006974 41 0.022
gene silencing GO:0016458 143 0.022
Yeast
germ cell development GO:0007281 351 0.022
secretion GO:0046903 147 0.022
Worm
response to external stimulus GO:0009605 289 0.022
regulation of cell cycle GO:0051726 194 0.022
macromolecule catabolic process GO:0009057 202 0.021
chromosome segregation GO:0007059 180 0.021
dna metabolic process GO:0006259 74 0.021
cellular protein modification process GO:0006464 207 0.021
Yeast
cellular component assembly involved in morphogenesis GO:0010927 183 0.021
Worm
protein modification process GO:0036211 207 0.021
Yeast
organelle assembly GO:0070925 214 0.020
Worm
positive regulation of cellular metabolic process GO:0031325 178 0.020
Worm
protein localization GO:0008104 205 0.020
innate immune response GO:0045087 190 0.020
phosphate containing compound metabolic process GO:0006796 232 0.019
regulation of nuclear division GO:0051783 115 0.019
dna repair GO:0006281 23 0.019
phosphorus metabolic process GO:0006793 232 0.019
striated muscle myosin thick filament assembly GO:0071688 138 0.019
Worm
regulation of meiotic cell cycle GO:0051445 136 0.019
establishment of organelle localization GO:0051656 123 0.019
cellular response to topologically incorrect protein GO:0035967 76 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
actomyosin structure organization GO:0031032 154 0.018
Worm
inductive cell migration GO:0040039 145 0.018
female gamete generation GO:0007292 254 0.018
regulation of cell cycle process GO:0010564 145 0.018
muscle cell differentiation GO:0042692 171 0.018
Worm
regulation of cell division GO:0051302 142 0.018
organic cyclic compound catabolic process GO:1901361 119 0.018
negative regulation of biosynthetic process GO:0009890 65 0.018
Yeast
posttranscriptional regulation of gene expression GO:0010608 166 0.018
myofibril assembly GO:0030239 154 0.018
Worm
negative regulation of cellular biosynthetic process GO:0031327 65 0.017
Yeast
regulation of response to stimulus GO:0048583 243 0.017
nervous system development GO:0007399 253 0.017
response to unfolded protein GO:0006986 71 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.017
Worm
negative regulation of rna biosynthetic process GO:1902679 53 0.017
Yeast
cell type specific apoptotic process GO:0097285 4 0.017
phagocytosis GO:0006909 115 0.017
myosin filament assembly GO:0031034 138 0.017
Worm
response to abiotic stimulus GO:0009628 152 0.017
striated muscle cell differentiation GO:0051146 158 0.017
Worm
er nucleus signaling pathway GO:0006984 66 0.016
response to topologically incorrect protein GO:0035966 82 0.016
nucleobase containing small molecule metabolic process GO:0055086 115 0.016
muscle structure development GO:0061061 191 0.016
Worm
oogenesis GO:0048477 229 0.016
oxoacid metabolic process GO:0043436 47 0.016
posttranscriptional gene silencing GO:0016441 143 0.016
aromatic compound catabolic process GO:0019439 116 0.016
negative regulation of cellular metabolic process GO:0031324 95 0.016
Yeast
muscle cell development GO:0055001 158 0.016
Worm
myosin filament organization GO:0031033 138 0.016
Worm
meiotic chromosome segregation GO:0045132 139 0.016
fertilization GO:0009566 63 0.016
cell morphogenesis GO:0000902 163 0.016
apoptotic cell clearance GO:0043277 111 0.016
regulation of lipid metabolic process GO:0019216 4 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
phagocytosis engulfment GO:0006911 98 0.016
chromosome organization GO:0051276 104 0.016
Yeast
regulation of cell communication GO:0010646 176 0.016
protein catabolic process GO:0030163 162 0.016
organic acid metabolic process GO:0006082 47 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
organelle localization GO:0051640 127 0.015
positive regulation of macromolecule metabolic process GO:0010604 149 0.015
Worm
striated muscle cell development GO:0055002 157 0.015
Worm
regulation of cytoplasmic transport GO:1903649 3 0.015
nucleobase containing compound catabolic process GO:0034655 114 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.015
Yeast
cellular response to unfolded protein GO:0034620 71 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
positive regulation of neuron differentiation GO:0045666 4 0.015
gene silencing by rna GO:0031047 143 0.015
membrane organization GO:0061024 135 0.015
cell projection organization GO:0030030 231 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
cell surface receptor signaling pathway GO:0007166 149 0.015
positive regulation of neurogenesis GO:0050769 4 0.015
neuron development GO:0048666 199 0.014
protein oligomerization GO:0051259 4 0.014
negative regulation of rna metabolic process GO:0051253 53 0.014
Yeast
cellular amino acid metabolic process GO:0006520 15 0.014
neurogenesis GO:0022008 236 0.014
regulation of meiosis GO:0040020 94 0.014
response to organic substance GO:0010033 131 0.014
regulation of signal transduction GO:0009966 135 0.014
nucleus organization GO:0006997 38 0.014
ribonucleotide metabolic process GO:0009259 99 0.014
nucleoside phosphate metabolic process GO:0006753 108 0.014
muscle tissue development GO:0060537 1 0.014
regulation of signaling GO:0023051 172 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.014
Worm
engulfment of apoptotic cell GO:0043652 94 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.014
Yeast
cuticle development GO:0042335 100 0.014
cell proliferation GO:0008283 116 0.014
carboxylic acid metabolic process GO:0019752 34 0.014
response to endoplasmic reticulum stress GO:0034976 71 0.013
neuron projection development GO:0031175 187 0.013
establishment of nucleus localization GO:0040023 55 0.013
membrane invagination GO:0010324 98 0.013
heterocycle catabolic process GO:0046700 119 0.013
cellular nitrogen compound catabolic process GO:0044270 119 0.013
rna interference GO:0016246 137 0.013
neuron differentiation GO:0030182 217 0.013
purine nucleoside metabolic process GO:0042278 92 0.013
neuromuscular junction development GO:0007528 2 0.013
amine metabolic process GO:0009308 15 0.013
carbohydrate derivative metabolic process GO:1901135 141 0.013
ribonucleoside triphosphate metabolic process GO:0009199 87 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.013
Yeast
organic substance transport GO:0071702 113 0.013
regulation of protein metabolic process GO:0051246 81 0.013
axon development GO:0061564 163 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.013
cellular amine metabolic process GO:0044106 15 0.013
embryonic morphogenesis GO:0048598 152 0.013
chromatin organization GO:0006325 32 0.013
Yeast
synaptic transmission GO:0007268 106 0.013
cellular response to organic substance GO:0071310 119 0.013
cell substrate adhesion GO:0031589 1 0.012
cell projection morphogenesis GO:0048858 148 0.012
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
adult behavior GO:0030534 3 0.012
cell morphogenesis involved in differentiation GO:0000904 112 0.012
purine nucleoside catabolic process GO:0006152 75 0.012
cellular response to abiotic stimulus GO:0071214 4 0.012
ribonucleoside metabolic process GO:0009119 98 0.012
nucleoside metabolic process GO:0009116 99 0.012
glycosyl compound metabolic process GO:1901657 100 0.012
response to temperature stimulus GO:0009266 66 0.012
generation of neurons GO:0048699 235 0.012
single organism catabolic process GO:0044712 129 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
ribonucleoprotein complex assembly GO:0022618 4 0.012
ribosome biogenesis GO:0042254 4 0.012
canonical wnt signaling pathway GO:0060070 3 0.012
ribose phosphate metabolic process GO:0019693 99 0.012
skeletal muscle organ development GO:0060538 3 0.012
glycosyl compound catabolic process GO:1901658 79 0.012
organophosphate metabolic process GO:0019637 125 0.012
nucleotide metabolic process GO:0009117 108 0.012
organonitrogen compound catabolic process GO:1901565 90 0.012
cell part morphogenesis GO:0032990 152 0.012
dauer larval development GO:0040024 92 0.012
single fertilization GO:0007338 61 0.012
spindle organization GO:0007051 92 0.012
pronuclear migration GO:0035046 51 0.012
feeding behavior GO:0007631 70 0.012
purine containing compound metabolic process GO:0072521 95 0.012
mitotic nuclear division GO:0007067 89 0.012
negative regulation of neurogenesis GO:0050768 4 0.011
pharyngeal pumping GO:0043050 58 0.011
regulation of response to wounding GO:1903034 1 0.011
system process GO:0003008 136 0.011
purine containing compound catabolic process GO:0072523 75 0.011
nucleotide catabolic process GO:0009166 77 0.011
nucleoside triphosphate metabolic process GO:0009141 87 0.011
phosphorylation GO:0016310 116 0.011
purine ribonucleotide catabolic process GO:0009154 75 0.011
positive regulation of nematode larval development GO:0061063 54 0.011
regulation of cell proliferation GO:0042127 105 0.011
chemotaxis GO:0006935 120 0.011
cellular ketone metabolic process GO:0042180 14 0.011
cellular response to chemical stimulus GO:0070887 129 0.011
cell cell signaling GO:0007267 118 0.011
purine ribonucleoside metabolic process GO:0046128 92 0.011
regeneration GO:0031099 4 0.011
positive regulation of biosynthetic process GO:0009891 109 0.011
Worm
regulation of epithelial cell differentiation GO:0030856 4 0.011
memory GO:0007613 3 0.011
nucleoside triphosphate catabolic process GO:0009143 72 0.011
nucleoside catabolic process GO:0009164 78 0.010
positive regulation of intracellular transport GO:0032388 2 0.010
response to other organism GO:0051707 101 0.010
positive regulation of rna metabolic process GO:0051254 103 0.010
Worm
eating behavior GO:0042755 59 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.010
purine ribonucleotide metabolic process GO:0009150 95 0.010
purine nucleotide metabolic process GO:0006163 95 0.010
regulation of cellular protein metabolic process GO:0032268 75 0.010
taxis GO:0042330 128 0.010

his-60 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.014