Caenorhabditis elegans

0 known processes

dct-18 (CELE_F58G1.4)

Protein DCT-18

dct-18 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
endoplasmic reticulum unfolded protein response GO:0030968 66 0.717
biosynthetic process GO:0009058 323 0.618
response to topologically incorrect protein GO:0035966 82 0.455
post embryonic development GO:0009791 2152 0.455
transport GO:0006810 1093 0.450
establishment of localization GO:0051234 1171 0.449
response to unfolded protein GO:0006986 71 0.376
embryo development GO:0009790 3052 0.367
er nucleus signaling pathway GO:0006984 66 0.362
aromatic compound biosynthetic process GO:0019438 192 0.358
nucleobase containing compound metabolic process GO:0006139 406 0.355
single organism transport GO:0044765 447 0.353
single organism localization GO:1902578 518 0.330
organic substance biosynthetic process GO:1901576 323 0.325
cellular nitrogen compound biosynthetic process GO:0044271 192 0.314
cellular response to topologically incorrect protein GO:0035967 76 0.312
cellular response to unfolded protein GO:0034620 71 0.303
programmed cell death GO:0012501 500 0.301
microvillus organization GO:0032528 1 0.298
cell migration GO:0016477 306 0.294
vesicle mediated transport GO:0016192 852 0.271
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.264
rna metabolic process GO:0016070 228 0.254
receptor mediated endocytosis GO:0006898 715 0.239
negative regulation of biological process GO:0048519 567 0.236
cellular biosynthetic process GO:0044249 315 0.232
endocytosis GO:0006897 819 0.231
heterocycle biosynthetic process GO:0018130 187 0.231
signaling GO:0023052 401 0.230
locomotion GO:0040011 1634 0.228
reproductive system development GO:0061458 850 0.223
embryo development ending in birth or egg hatching GO:0009792 2992 0.221
single organism signaling GO:0044700 401 0.220
single organism reproductive process GO:0044702 1196 0.213
organ development GO:0048513 1102 0.207
response to endoplasmic reticulum stress GO:0034976 71 0.207
multicellular organism reproduction GO:0032504 819 0.205
cell death GO:0008219 547 0.198
apoptotic process GO:0006915 478 0.191
regulation of biological quality GO:0065008 741 0.177
cellular response to stress GO:0033554 162 0.176
developmental process involved in reproduction GO:0003006 1165 0.173
immune response GO:0006955 192 0.172
hermaphrodite genitalia development GO:0040035 734 0.167
cell development GO:0048468 696 0.166
organonitrogen compound metabolic process GO:1901564 151 0.164
phosphate containing compound metabolic process GO:0006796 232 0.163
inductive cell migration GO:0040039 145 0.163
death GO:0016265 547 0.157
small molecule metabolic process GO:0044281 186 0.148
reproductive structure development GO:0048608 850 0.144
nucleic acid templated transcription GO:0097659 169 0.144
organic cyclic compound biosynthetic process GO:1901362 195 0.142
glycosyl compound metabolic process GO:1901657 100 0.142
aging GO:0007568 812 0.142
macromolecule localization GO:0033036 771 0.140
organophosphate metabolic process GO:0019637 125 0.138
nucleobase containing small molecule metabolic process GO:0055086 115 0.137
gene expression GO:0010467 412 0.136
regulation of nitrogen compound metabolic process GO:0051171 222 0.134
rna biosynthetic process GO:0032774 169 0.134
lipid biosynthetic process GO:0008610 28 0.132
sexual reproduction GO:0019953 546 0.130
cellular macromolecule biosynthetic process GO:0034645 247 0.129
regulation of gene expression GO:0010468 366 0.126
regulation of response to stimulus GO:0048583 243 0.117
genitalia development GO:0048806 741 0.116
response to chemical GO:0042221 356 0.114
regulation of developmental process GO:0050793 684 0.113
regulation of multicellular organismal process GO:0051239 726 0.113
response to organic substance GO:0010033 131 0.110
muscle tissue development GO:0060537 1 0.110
body morphogenesis GO:0010171 620 0.103
development of primary sexual characteristics GO:0045137 840 0.103
regulation of signaling GO:0023051 172 0.101
anatomical structure formation involved in morphogenesis GO:0048646 250 0.101
multi organism reproductive process GO:0044703 867 0.100
regulation of rna metabolic process GO:0051252 173 0.099
phosphorus metabolic process GO:0006793 232 0.099
gamete generation GO:0007276 461 0.098
cell projection organization GO:0030030 231 0.098
gonad development GO:0008406 840 0.096
organic substance catabolic process GO:1901575 294 0.094
nucleobase containing compound biosynthetic process GO:0034654 184 0.094
determination of adult lifespan GO:0008340 812 0.093
response to wounding GO:0009611 4 0.093
cell motility GO:0048870 313 0.091
negative regulation of transcription dna templated GO:0045892 53 0.086
positive regulation of developmental process GO:0051094 408 0.086
lipid storage GO:0019915 565 0.085
nuclear pore localization GO:0051664 2 0.085
nervous system development GO:0007399 253 0.085
lipid localization GO:0010876 573 0.084
maintenance of location GO:0051235 580 0.082
regulation of transcription dna templated GO:0006355 164 0.079
regulation of metabolic process GO:0019222 478 0.078
nucleoside metabolic process GO:0009116 99 0.078
innate immune response GO:0045087 190 0.077
negative regulation of gene expression GO:0010629 217 0.077
signal transduction GO:0007165 317 0.076
regulation of signal transduction GO:0009966 135 0.076
tissue development GO:0009888 112 0.074
transcription dna templated GO:0006351 168 0.074
multicellular organismal aging GO:0010259 812 0.072
lipid metabolic process GO:0006629 77 0.072
secretion GO:0046903 147 0.071
cellular component movement GO:0006928 388 0.071
establishment of localization in cell GO:0051649 318 0.067
regulation of primary metabolic process GO:0080090 292 0.066
cellular localization GO:0051641 360 0.066
small molecule biosynthetic process GO:0044283 38 0.065
catabolic process GO:0009056 318 0.064
positive regulation of cellular process GO:0048522 332 0.062
carbohydrate derivative metabolic process GO:1901135 141 0.062
cellular response to dna damage stimulus GO:0006974 41 0.061
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.061
negative regulation of rna biosynthetic process GO:1902679 53 0.061
regulation of multicellular organismal development GO:2000026 317 0.061
single organism biosynthetic process GO:0044711 91 0.060
positive regulation of multicellular organismal process GO:0051240 417 0.060
meiotic cell cycle GO:0051321 335 0.059
macromolecule modification GO:0043412 218 0.059
generation of neurons GO:0048699 235 0.058
multicellular organismal reproductive process GO:0048609 815 0.058
cellular protein modification process GO:0006464 207 0.057
positive regulation of developmental growth GO:0048639 354 0.057
regulation of lipid biosynthetic process GO:0046890 1 0.056
positive regulation of macromolecule metabolic process GO:0010604 149 0.056
sex differentiation GO:0007548 909 0.056
regulation of rna biosynthetic process GO:2001141 165 0.055
regulation of nucleic acid templated transcription GO:1903506 165 0.053
macromolecule biosynthetic process GO:0009059 250 0.053
female gamete generation GO:0007292 254 0.053
oviposition GO:0018991 364 0.052
meiotic nuclear division GO:0007126 300 0.052
regulation of biosynthetic process GO:0009889 189 0.051
positive regulation of neuron projection development GO:0010976 4 0.051
nucleotide metabolic process GO:0009117 108 0.050
tube morphogenesis GO:0035239 79 0.050
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.050
negative regulation of metabolic process GO:0009892 240 0.049
protein localization GO:0008104 205 0.049
multi organism behavior GO:0051705 389 0.049
regulation of cellular biosynthetic process GO:0031326 189 0.049
protein metabolic process GO:0019538 422 0.048
regulation of anatomical structure morphogenesis GO:0022603 51 0.046
organic substance transport GO:0071702 113 0.046
microvillus assembly GO:0030033 1 0.045
cellular protein metabolic process GO:0044267 279 0.044
multi organism reproductive behavior GO:0044705 387 0.043
cellular protein localization GO:0034613 75 0.043
negative regulation of macromolecule metabolic process GO:0010605 229 0.043
muscle organ morphogenesis GO:0048644 4 0.042
cellular lipid metabolic process GO:0044255 40 0.042
monovalent inorganic cation homeostasis GO:0055067 6 0.041
germ cell development GO:0007281 351 0.040
response to external biotic stimulus GO:0043207 101 0.040
reproductive behavior GO:0019098 387 0.040
regulation of localization GO:0032879 194 0.039
defense response GO:0006952 296 0.039
multicellular organismal reproductive behavior GO:0033057 384 0.038
organic cyclic compound catabolic process GO:1901361 119 0.037
regulation of growth GO:0040008 409 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.037
nucleoside phosphate metabolic process GO:0006753 108 0.037
regulation of macromolecule metabolic process GO:0060255 421 0.037
negative regulation of cellular biosynthetic process GO:0031327 65 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.036
developmental growth GO:0048589 412 0.036
positive regulation of multicellular organism growth GO:0040018 352 0.036
multi multicellular organism process GO:0044706 390 0.036
oogenesis GO:0048477 229 0.036
regulation of response to wounding GO:1903034 1 0.035
cellular response to chemical stimulus GO:0070887 129 0.034
regulation of lipid metabolic process GO:0019216 4 0.034
response to acid chemical GO:0001101 4 0.033
protein modification process GO:0036211 207 0.033
cellular amine metabolic process GO:0044106 15 0.033
regulation of cell communication GO:0010646 176 0.032
heterocycle catabolic process GO:0046700 119 0.032
system process GO:0003008 136 0.032
nuclear pore distribution GO:0031081 2 0.031
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.031
regulation of developmental growth GO:0048638 389 0.031
oxoacid metabolic process GO:0043436 47 0.031
phospholipid biosynthetic process GO:0008654 11 0.031
localization of cell GO:0051674 313 0.031
positive regulation of neuron differentiation GO:0045666 4 0.030
tube development GO:0035295 126 0.029
regulation of gene expression epigenetic GO:0040029 163 0.029
regulation of cellular ketone metabolic process GO:0010565 3 0.029
regulation of cellular metabolic process GO:0031323 305 0.029
regulation of multicellular organism growth GO:0040014 373 0.029
nucleic acid metabolic process GO:0090304 299 0.028
cytoskeleton organization GO:0007010 339 0.028
cellular component assembly GO:0022607 293 0.028
cell fate commitment GO:0045165 139 0.028
inactivation of mapkkk activity GO:0051390 2 0.028
cell division GO:0051301 262 0.027
negative regulation of multicellular organismal process GO:0051241 236 0.027
amine metabolic process GO:0009308 15 0.027
ribonucleoside metabolic process GO:0009119 98 0.027
regulation of cell proliferation GO:0042127 105 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.027
regulation of phosphorus metabolic process GO:0051174 81 0.027
organ morphogenesis GO:0009887 67 0.027
positive regulation of cell projection organization GO:0031346 4 0.027
organonitrogen compound biosynthetic process GO:1901566 44 0.026
tissue morphogenesis GO:0048729 65 0.026
positive regulation of growth GO:0045927 369 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.026
growth GO:0040007 562 0.026
organonitrogen compound catabolic process GO:1901565 90 0.026
nucleoside catabolic process GO:0009164 78 0.025
regulation of catalytic activity GO:0050790 78 0.025
phosphorylation GO:0016310 116 0.025
response to biotic stimulus GO:0009607 101 0.025
cellular component assembly involved in morphogenesis GO:0010927 183 0.025
chemical homeostasis GO:0048878 29 0.024
secretion by cell GO:0032940 138 0.024
positive regulation of response to stimulus GO:0048584 55 0.024
neuron development GO:0048666 199 0.024
aromatic compound catabolic process GO:0019439 116 0.024
cellular nitrogen compound catabolic process GO:0044270 119 0.024
phagocytosis GO:0006909 115 0.024
positive regulation of biosynthetic process GO:0009891 109 0.023
negative regulation of biosynthetic process GO:0009890 65 0.023
response to bacterium GO:0009617 86 0.023
cell surface receptor signaling pathway GO:0007166 149 0.023
regulation of apoptotic signaling pathway GO:2001233 1 0.023
dna repair GO:0006281 23 0.023
positive regulation of cellular biosynthetic process GO:0031328 109 0.023
intracellular receptor signaling pathway GO:0030522 2 0.023
cellular component morphogenesis GO:0032989 318 0.022
mitotic nuclear envelope reassembly GO:0007084 3 0.022
muscle structure development GO:0061061 191 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.022
cellular protein complex assembly GO:0043623 178 0.022
sensory organ morphogenesis GO:0090596 2 0.022
myosin filament organization GO:0031033 138 0.021
striated muscle cell differentiation GO:0051146 158 0.021
gene silencing GO:0016458 143 0.021
organic acid metabolic process GO:0006082 47 0.021
chromosome segregation GO:0007059 180 0.020
regulation of cellular component organization GO:0051128 248 0.020
protein catabolic process GO:0030163 162 0.020
cellular catabolic process GO:0044248 199 0.020
cellular response to organic substance GO:0071310 119 0.020
chromosome organization GO:0051276 104 0.019
carboxylic acid metabolic process GO:0019752 34 0.019
positive regulation of cellular metabolic process GO:0031325 178 0.019
cellular component biogenesis GO:0044085 297 0.019
negative regulation of developmental process GO:0051093 227 0.019
contractile ring contraction GO:0036213 3 0.019
ribonucleoside triphosphate catabolic process GO:0009203 72 0.018
organophosphate biosynthetic process GO:0090407 26 0.018
regulation of molecular function GO:0065009 89 0.018
ribonucleotide metabolic process GO:0009259 99 0.018
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.018
cell recognition GO:0008037 85 0.018
carbohydrate derivative catabolic process GO:1901136 82 0.018
striated muscle myosin thick filament assembly GO:0071688 138 0.018
cellular ketone metabolic process GO:0042180 14 0.018
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.017
cellular amino acid metabolic process GO:0006520 15 0.017
membrane organization GO:0061024 135 0.017
ribose phosphate metabolic process GO:0019693 99 0.017
cellular macromolecule localization GO:0070727 75 0.017
intracellular transport GO:0046907 77 0.017
single organism carbohydrate metabolic process GO:0044723 29 0.017
transcription from rna polymerase ii promoter GO:0006366 149 0.017
cuticle development GO:0042335 100 0.017
dna metabolic process GO:0006259 74 0.017
ovulation GO:0030728 33 0.017
organelle organization GO:0006996 783 0.016
neuron differentiation GO:0030182 217 0.016
negative regulation of vulval development GO:0040027 206 0.016
purine containing compound metabolic process GO:0072521 95 0.016
negative regulation of response to stimulus GO:0048585 73 0.016
molting cycle GO:0042303 281 0.015
glycosyl compound catabolic process GO:1901658 79 0.015
defense response to bacterium GO:0042742 86 0.015
regulation of macromolecule biosynthetic process GO:0010556 189 0.015
negative regulation of cellular process GO:0048523 239 0.015
cell projection morphogenesis GO:0048858 148 0.014
response to other organism GO:0051707 101 0.014
negative regulation of rna metabolic process GO:0051253 53 0.014
ion homeostasis GO:0050801 21 0.014
intercellular transport GO:0010496 1 0.014
behavior GO:0007610 527 0.014
positive regulation of metabolic process GO:0009893 187 0.014
positive regulation of neurogenesis GO:0050769 4 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
head development GO:0060322 1 0.014
macromolecule catabolic process GO:0009057 202 0.014
macromolecular complex assembly GO:0065003 193 0.014
negative regulation of post embryonic development GO:0048581 208 0.013
negative regulation of nematode larval development GO:0061064 208 0.013
cell cycle process GO:0022402 482 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.013
cell proliferation GO:0008283 116 0.013
regulation of vulval development GO:0040028 248 0.013
cell morphogenesis GO:0000902 163 0.013
regulation of phosphate metabolic process GO:0019220 81 0.013
negative regulation of cellular metabolic process GO:0031324 95 0.013
homeostatic process GO:0042592 51 0.013
purine nucleoside metabolic process GO:0042278 92 0.013
response to inorganic substance GO:0010035 50 0.013
muscle cell differentiation GO:0042692 171 0.013
regulation of response to stress GO:0080134 28 0.013
axon development GO:0061564 163 0.012
regulation of post embryonic development GO:0048580 260 0.012
regulation of cell migration GO:0030334 55 0.012
monocarboxylic acid metabolic process GO:0032787 22 0.012
protein transport GO:0015031 45 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
regulation of transport GO:0051049 91 0.012
establishment of rna localization GO:0051236 3 0.012
myosin filament assembly GO:0031034 138 0.012
actin cytoskeleton organization GO:0030036 184 0.012
rna interference GO:0016246 137 0.012
actomyosin structure organization GO:0031032 154 0.012
protein localization to organelle GO:0033365 37 0.012
cellular response to inorganic substance GO:0071241 3 0.012
purine ribonucleoside metabolic process GO:0046128 92 0.012
protein complex assembly GO:0006461 186 0.012
peptidyl amino acid modification GO:0018193 58 0.012
response to metal ion GO:0010038 33 0.012
internal peptidyl lysine acetylation GO:0018393 3 0.012
neurological system process GO:0050877 53 0.012
lipid modification GO:0030258 4 0.011
organelle assembly GO:0070925 214 0.011
defense response to other organism GO:0098542 100 0.011
mitotic cell cycle process GO:1903047 194 0.011
negative regulation of nucleic acid templated transcription GO:1903507 53 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.011
intracellular signal transduction GO:0035556 96 0.011
actin filament based process GO:0030029 191 0.011
regulation of cell motility GO:2000145 57 0.011
purine nucleoside triphosphate metabolic process GO:0009144 87 0.011
muscle organ development GO:0007517 26 0.011
phagocytosis engulfment GO:0006911 98 0.011
adult behavior GO:0030534 3 0.011
multicellular organism growth GO:0035264 385 0.011
lipid oxidation GO:0034440 1 0.011
gene silencing by rna GO:0031047 143 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.011
posttranscriptional gene silencing by rna GO:0035194 143 0.011
excretion GO:0007588 49 0.011
neuron projection development GO:0031175 187 0.011
response to abiotic stimulus GO:0009628 152 0.010
ion transport GO:0006811 113 0.010
regulation of programmed cell death GO:0043067 50 0.010
cell type specific apoptotic process GO:0097285 4 0.010
cation homeostasis GO:0055080 20 0.010
regulation of cell death GO:0010941 65 0.010
fatty acid oxidation GO:0019395 1 0.010
positive regulation of cell death GO:0010942 38 0.010

dct-18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.074
congenital muscular dystrophy DOID:0050557 0 0.074
muscular disease DOID:0080000 0 0.074
muscular dystrophy DOID:9884 0 0.074
disease of anatomical entity DOID:7 0 0.074
musculoskeletal system disease DOID:17 0 0.074
muscle tissue disease DOID:66 0 0.074
lipodystrophy DOID:811 0 0.063
skin disease DOID:37 0 0.063
integumentary system disease DOID:16 0 0.063
familial partial lipodystrophy DOID:0050440 0 0.063
progeria DOID:3911 0 0.040
limb girdle muscular dystrophy DOID:11724 0 0.021
heart disease DOID:114 0 0.018
cardiomyopathy DOID:0050700 0 0.018
cardiovascular system disease DOID:1287 0 0.018
nervous system disease DOID:863 0 0.016
emery dreifuss muscular dystrophy DOID:11726 0 0.013