Caenorhabditis elegans

169 known processes

tir-1 (CELE_F13B10.1)

Protein TIR-1

tir-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.622
post embryonic development GO:0009791 2152 0.551
single organism reproductive process GO:0044702 1196 0.527
embryo development ending in birth or egg hatching GO:0009792 2992 0.522
multicellular organism reproduction GO:0032504 819 0.442
cell cycle process GO:0022402 482 0.375
reproductive system development GO:0061458 850 0.348
gamete generation GO:0007276 461 0.296
establishment of localization GO:0051234 1171 0.285
transport GO:0006810 1093 0.282
multicellular organismal reproductive process GO:0048609 815 0.278
cell cycle GO:0007049 526 0.275
multicellular organismal reproductive behavior GO:0033057 384 0.273
organ development GO:0048513 1102 0.270
receptor mediated endocytosis GO:0006898 715 0.230
genitalia development GO:0048806 741 0.229
signaling GO:0023052 401 0.219
sexual reproduction GO:0019953 546 0.210
growth GO:0040007 562 0.199
vesicle mediated transport GO:0016192 852 0.191
hermaphrodite genitalia development GO:0040035 734 0.181
organelle fission GO:0048285 363 0.174
developmental process involved in reproduction GO:0003006 1165 0.170
multi organism reproductive process GO:0044703 867 0.169
cell death GO:0008219 547 0.166
Mouse
endocytosis GO:0006897 819 0.165
body morphogenesis GO:0010171 620 0.158
response to biotic stimulus GO:0009607 101 0.154
protein metabolic process GO:0019538 422 0.153
developmental growth GO:0048589 412 0.151
sex differentiation GO:0007548 909 0.147
regulation of response to stimulus GO:0048583 243 0.144
locomotion GO:0040011 1634 0.137
multi multicellular organism process GO:0044706 390 0.136
meiotic nuclear division GO:0007126 300 0.136
phosphorylation GO:0016310 116 0.135
gonad development GO:0008406 840 0.134
meiotic cell cycle GO:0051321 335 0.134
regulation of multicellular organismal process GO:0051239 726 0.129
Mouse
organelle organization GO:0006996 783 0.125
establishment of localization in cell GO:0051649 318 0.121
development of primary sexual characteristics GO:0045137 840 0.114
reproductive behavior GO:0019098 387 0.107
regulation of cell communication GO:0010646 176 0.105
multi organism behavior GO:0051705 389 0.097
regulation of multicellular organism growth GO:0040014 373 0.094
reproductive structure development GO:0048608 850 0.093
oviposition GO:0018991 364 0.092
multi organism reproductive behavior GO:0044705 387 0.092
multicellular organism growth GO:0035264 385 0.091
inductive cell migration GO:0040039 145 0.091
regulation of metabolic process GO:0019222 478 0.089
single organism transport GO:0044765 447 0.086
female gamete generation GO:0007292 254 0.082
regulation of phosphorylation GO:0042325 45 0.080
regulation of developmental process GO:0050793 684 0.079
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.078
macromolecule localization GO:0033036 771 0.077
regulation of developmental growth GO:0048638 389 0.076
cellular biosynthetic process GO:0044249 315 0.071
aging GO:0007568 812 0.071
organic substance biosynthetic process GO:1901576 323 0.071
protein modification process GO:0036211 207 0.066
response to other organism GO:0051707 101 0.066
muscle system process GO:0003012 43 0.065
system process GO:0003008 136 0.065
lipid localization GO:0010876 573 0.062
regulation of growth GO:0040008 409 0.061
stress activated mapk cascade GO:0051403 10 0.060
positive regulation of stress activated mapk cascade GO:0032874 3 0.059
single organism localization GO:1902578 518 0.059
positive regulation of developmental growth GO:0048639 354 0.058
germ cell development GO:0007281 351 0.058
phosphate containing compound metabolic process GO:0006796 232 0.058
sensory organ morphogenesis GO:0090596 2 0.057
positive regulation of multicellular organism growth GO:0040018 352 0.057
single organism organelle organization GO:1902589 501 0.055
positive regulation of jnk cascade GO:0046330 3 0.054
maintenance of location GO:0051235 580 0.053
multicellular organismal aging GO:0010259 812 0.051
lipid storage GO:0019915 565 0.050
signal transduction GO:0007165 317 0.050
programmed cell death GO:0012501 500 0.049
Mouse
macromolecule modification GO:0043412 218 0.049
macromolecular complex subunit organization GO:0043933 320 0.048
cellular localization GO:0051641 360 0.048
determination of adult lifespan GO:0008340 812 0.048
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.048
apoptotic process GO:0006915 478 0.047
Mouse
cellular protein metabolic process GO:0044267 279 0.047
behavior GO:0007610 527 0.047
single organism signaling GO:0044700 401 0.046
negative regulation of biological process GO:0048519 567 0.046
cell development GO:0048468 696 0.046
Mouse
oogenesis GO:0048477 229 0.046
regulation of cell cycle GO:0051726 194 0.045
stress activated protein kinase signaling cascade GO:0031098 10 0.045
regulation of mapk cascade GO:0043408 23 0.045
regulation of biological quality GO:0065008 741 0.044
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacterium GO:1902097 4 0.044
regulation of macromolecule metabolic process GO:0060255 421 0.044
positive regulation of growth GO:0045927 369 0.043
jnk cascade GO:0007254 8 0.043
regulation of nitrogen compound metabolic process GO:0051171 222 0.043
dorsal ventral axon guidance GO:0033563 19 0.041
positive regulation of cell cycle GO:0045787 55 0.041
synaptic transmission GO:0007268 106 0.040
tissue development GO:0009888 112 0.038
nervous system development GO:0007399 253 0.038
Mouse
regulation of cellular component organization GO:0051128 248 0.038
Mouse
gene expression GO:0010467 412 0.037
spermatogenesis GO:0007283 41 0.036
muscle contraction GO:0006936 43 0.036
phosphorus metabolic process GO:0006793 232 0.036
negative regulation of macromolecule metabolic process GO:0010605 229 0.036
male gamete generation GO:0048232 41 0.035
organic cyclic compound biosynthetic process GO:1901362 195 0.034
single organism cellular localization GO:1902580 72 0.034
response to abiotic stimulus GO:0009628 152 0.033
death GO:0016265 547 0.032
Mouse
positive regulation of cellular process GO:0048522 332 0.031
skeletal muscle organ development GO:0060538 3 0.031
dauer larval development GO:0040024 92 0.031
cell morphogenesis GO:0000902 163 0.031
Mouse
positive regulation of metabolic process GO:0009893 187 0.031
macromolecule catabolic process GO:0009057 202 0.030
biosynthetic process GO:0009058 323 0.030
establishment of cell polarity GO:0030010 46 0.030
protein phosphorylation GO:0006468 85 0.030
membrane organization GO:0061024 135 0.030
negative regulation of metabolic process GO:0009892 240 0.029
cellular response to organic substance GO:0071310 119 0.028
cellular component morphogenesis GO:0032989 318 0.028
Mouse
regulation of intracellular signal transduction GO:1902531 77 0.027
defense response to other organism GO:0098542 100 0.025
regulation of behavior GO:0050795 97 0.025
regulation of signaling GO:0023051 172 0.025
response to bacterium GO:0009617 86 0.025
meiotic cell cycle process GO:1903046 170 0.025
regulation of signal transduction GO:0009966 135 0.025
cellular macromolecule biosynthetic process GO:0034645 247 0.025
response to transition metal nanoparticle GO:1990267 18 0.025
regulation of molecular function GO:0065009 89 0.024
positive regulation of cell communication GO:0010647 69 0.024
positive regulation of cell death GO:0010942 38 0.024
response to chemical GO:0042221 356 0.023
Mouse
regulation of gene expression epigenetic GO:0040029 163 0.022
vulval development GO:0040025 333 0.022
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.021
protein complex subunit organization GO:0071822 280 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
oocyte axis specification GO:0007309 2 0.021
head development GO:0060322 1 0.020
post embryonic organ development GO:0048569 336 0.020
embryonic body morphogenesis GO:0010172 49 0.020
positive regulation of phosphate metabolic process GO:0045937 56 0.020
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.020
epithelial cell proliferation GO:0050673 1 0.020
organ morphogenesis GO:0009887 67 0.020
dna metabolic process GO:0006259 74 0.020
protein complex assembly GO:0006461 186 0.019
cell division GO:0051301 262 0.019
response to osmotic stress GO:0006970 29 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
mitotic cell cycle process GO:1903047 194 0.019
negative regulation of cellular process GO:0048523 239 0.019
positive regulation of macromolecule metabolic process GO:0010604 149 0.018
transcription from rna polymerase ii promoter GO:0006366 149 0.018
muscle tissue development GO:0060537 1 0.018
molting cycle GO:0042303 281 0.018
response to external biotic stimulus GO:0043207 101 0.018
nucleobase containing compound biosynthetic process GO:0034654 184 0.018
protein catabolic process GO:0030163 162 0.018
regulation of cellular protein metabolic process GO:0032268 75 0.018
cellular protein modification process GO:0006464 207 0.018
cellular macromolecule catabolic process GO:0044265 73 0.018
regulation of stress activated mapk cascade GO:0032872 5 0.018
ovulation GO:0030728 33 0.018
chromosome organization GO:0051276 104 0.017
secretion GO:0046903 147 0.017
regulation of reproductive process GO:2000241 66 0.017
chromosome segregation GO:0007059 180 0.017
cell motility GO:0048870 313 0.017
regulation of locomotion GO:0040012 161 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
positive regulation of phosphorus metabolic process GO:0010562 56 0.016
protein complex biogenesis GO:0070271 186 0.016
cellular nitrogen compound biosynthetic process GO:0044271 192 0.016
cytokinesis GO:0000910 80 0.016
cellular response to stress GO:0033554 162 0.015
regulation of primary metabolic process GO:0080090 292 0.015
response to temperature stimulus GO:0009266 66 0.015
er nucleus signaling pathway GO:0006984 66 0.015
protein localization GO:0008104 205 0.015
single fertilization GO:0007338 61 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.014
positive regulation of developmental process GO:0051094 408 0.014
fertilization GO:0009566 63 0.014
cellular response to abiotic stimulus GO:0071214 4 0.014
collagen and cuticulin based cuticle development GO:0040002 99 0.014
single organism behavior GO:0044708 83 0.014
intracellular receptor signaling pathway GO:0030522 2 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 5 0.014
regulation of macromolecule biosynthetic process GO:0010556 189 0.014
meiotic chromosome segregation GO:0045132 139 0.014
cellular component movement GO:0006928 388 0.014
negative regulation of cell communication GO:0010648 61 0.014
cellular protein complex assembly GO:0043623 178 0.014
gene silencing by rna GO:0031047 143 0.014
regulation of bmp signaling pathway GO:0030510 3 0.013
positive regulation of cellular metabolic process GO:0031325 178 0.013
cellular macromolecular complex assembly GO:0034622 184 0.013
axis specification GO:0009798 23 0.013
regulation of mitotic cell cycle GO:0007346 76 0.013
intracellular signal transduction GO:0035556 96 0.013
establishment of spindle orientation GO:0051294 34 0.013
negative regulation of response to stimulus GO:0048585 73 0.013
macromolecule biosynthetic process GO:0009059 250 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
response to acid chemical GO:0001101 4 0.013
macromolecular complex assembly GO:0065003 193 0.013
secretion by cell GO:0032940 138 0.013
muscle structure development GO:0061061 191 0.013
nucleobase containing compound metabolic process GO:0006139 406 0.013
response to oxygen containing compound GO:1901700 44 0.013
Mouse
cell proliferation GO:0008283 116 0.013
regulation of jnk cascade GO:0046328 5 0.013
oocyte construction GO:0007308 2 0.013
regulation of cell division GO:0051302 142 0.012
aromatic compound biosynthetic process GO:0019438 192 0.012
regulation of gene expression GO:0010468 366 0.012
chromatin remodeling GO:0006338 2 0.012
gene silencing GO:0016458 143 0.012
cellular protein localization GO:0034613 75 0.012
negative regulation of response to external stimulus GO:0032102 3 0.012
positive regulation of multicellular organismal process GO:0051240 417 0.012
defense response to gram negative bacterium GO:0050829 64 0.012
regulation of phosphate metabolic process GO:0019220 81 0.012
proteolysis GO:0006508 61 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
organic substance catabolic process GO:1901575 294 0.012
oxoacid metabolic process GO:0043436 47 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.011
regulation of cell cycle process GO:0010564 145 0.011
anatomical structure formation involved in morphogenesis GO:0048646 250 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
heterocycle biosynthetic process GO:0018130 187 0.011
positive regulation of programmed cell death GO:0043068 27 0.011
negative regulation of signaling GO:0023057 61 0.011
cell type specific apoptotic process GO:0097285 4 0.011
regulation of localization GO:0032879 194 0.011
regulation of phosphorus metabolic process GO:0051174 81 0.011
regulation of multicellular organismal development GO:2000026 317 0.011
Mouse
cellular response to chemical stimulus GO:0070887 129 0.011
establishment of protein localization to membrane GO:0090150 3 0.010
neuromuscular junction development GO:0007528 2 0.010
response to external stimulus GO:0009605 289 0.010
amine metabolic process GO:0009308 15 0.010
regulation of programmed cell death GO:0043067 50 0.010
Mouse
positive regulation of cell migration GO:0030335 3 0.010
negative regulation of molecular function GO:0044092 20 0.010
proteasomal protein catabolic process GO:0010498 20 0.010
organelle localization GO:0051640 127 0.010
cell migration GO:0016477 306 0.010
activation of jun kinase activity GO:0007257 3 0.010

tir-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.010