Caenorhabditis elegans

16 known processes

rev-1 (CELE_ZK675.2)

Protein REV-1

rev-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multicellular organismal reproductive process GO:0048609 815 0.510
reproductive structure development GO:0048608 850 0.330
sexual reproduction GO:0019953 546 0.291
embryo development GO:0009790 3052 0.289
single organism reproductive process GO:0044702 1196 0.287
sex differentiation GO:0007548 909 0.233
reproductive system development GO:0061458 850 0.228
developmental process involved in reproduction GO:0003006 1165 0.208
gamete generation GO:0007276 461 0.203
negative regulation of biological process GO:0048519 567 0.197
locomotion GO:0040011 1634 0.194
regulation of cell cycle process GO:0010564 145 0.193
multicellular organism reproduction GO:0032504 819 0.179
cell division GO:0051301 262 0.178
organ development GO:0048513 1102 0.168
organophosphate metabolic process GO:0019637 125 0.166
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.152
negative regulation of vulval development GO:0040027 206 0.143
protein complex subunit organization GO:0071822 280 0.143
regulation of cell cycle GO:0051726 194 0.140
development of primary sexual characteristics GO:0045137 840 0.120
post embryonic development GO:0009791 2152 0.117
multi organism reproductive process GO:0044703 867 0.113
regulation of multicellular organismal development GO:2000026 317 0.108
regulation of biological quality GO:0065008 741 0.100
negative regulation of multicellular organismal process GO:0051241 236 0.097
hermaphrodite genitalia development GO:0040035 734 0.096
regulation of cell division GO:0051302 142 0.095
negative regulation of developmental process GO:0051093 227 0.094
mitotic cell cycle process GO:1903047 194 0.093
cell cycle process GO:0022402 482 0.092
regulation of multicellular organismal process GO:0051239 726 0.091
vulval development GO:0040025 333 0.090
regulation of nuclear division GO:0051783 115 0.086
regulation of cellular component organization GO:0051128 248 0.085
determination of adult lifespan GO:0008340 812 0.085
germ cell development GO:0007281 351 0.083
single organism organelle organization GO:1902589 501 0.080
regulation of cell migration GO:0030334 55 0.079
macromolecule catabolic process GO:0009057 202 0.077
positive regulation of epithelial cell proliferation GO:0050679 1 0.077
cellular component movement GO:0006928 388 0.075
innate immune response GO:0045087 190 0.073
lipid storage GO:0019915 565 0.072
macromolecule modification GO:0043412 218 0.071
maintenance of location GO:0051235 580 0.071
lipid localization GO:0010876 573 0.069
regulation of metabolic process GO:0019222 478 0.068
Fly
macromolecule localization GO:0033036 771 0.068
striated muscle cell differentiation GO:0051146 158 0.068
localization of cell GO:0051674 313 0.067
transport GO:0006810 1093 0.066
aging GO:0007568 812 0.064
single organism cellular localization GO:1902580 72 0.064
small molecule metabolic process GO:0044281 186 0.060
heterocycle catabolic process GO:0046700 119 0.059
catabolic process GO:0009056 318 0.059
post embryonic organ development GO:0048569 336 0.058
female gamete generation GO:0007292 254 0.056
genitalia development GO:0048806 741 0.056
multicellular organismal aging GO:0010259 812 0.056
cell cycle GO:0007049 526 0.055
cellular catabolic process GO:0044248 199 0.054
cellular response to stress GO:0033554 162 0.053
Mouse Fly
cell migration GO:0016477 306 0.053
exocytosis GO:0006887 15 0.052
regulation of macromolecule metabolic process GO:0060255 421 0.051
Fly
cellular nitrogen compound catabolic process GO:0044270 119 0.050
gene silencing GO:0016458 143 0.048
cellular component biogenesis GO:0044085 297 0.048
purine nucleoside metabolic process GO:0042278 92 0.048
aromatic compound catabolic process GO:0019439 116 0.048
organonitrogen compound metabolic process GO:1901564 151 0.047
protein modification process GO:0036211 207 0.046
regulation of gene expression GO:0010468 366 0.046
regulation of organelle organization GO:0033043 164 0.045
glycosyl compound metabolic process GO:1901657 100 0.045
nucleobase containing small molecule metabolic process GO:0055086 115 0.045
single organism localization GO:1902578 518 0.045
embryo development ending in birth or egg hatching GO:0009792 2992 0.044
nucleoside phosphate metabolic process GO:0006753 108 0.044
purine ribonucleoside metabolic process GO:0046128 92 0.044
negative regulation of post embryonic development GO:0048581 208 0.043
regulation of gene expression epigenetic GO:0040029 163 0.043
response to external stimulus GO:0009605 289 0.041
nucleobase containing compound catabolic process GO:0034655 114 0.041
negative regulation of nematode larval development GO:0061064 208 0.041
cellular component assembly involved in morphogenesis GO:0010927 183 0.040
regulation of mitotic cell cycle GO:0007346 76 0.039
defense response GO:0006952 296 0.039
anatomical structure formation involved in morphogenesis GO:0048646 250 0.039
negative regulation of macromolecule metabolic process GO:0010605 229 0.039
organic substance catabolic process GO:1901575 294 0.038
nucleoside metabolic process GO:0009116 99 0.038
organophosphate catabolic process GO:0046434 81 0.038
regulation of cell morphogenesis GO:0022604 40 0.037
cell motility GO:0048870 313 0.036
posttranscriptional gene silencing by rna GO:0035194 143 0.036
nucleotide metabolic process GO:0009117 108 0.036
regulation of primary metabolic process GO:0080090 292 0.036
Fly
immune response GO:0006955 192 0.036
regulation of cellular component movement GO:0051270 62 0.035
single organism catabolic process GO:0044712 129 0.035
organonitrogen compound catabolic process GO:1901565 90 0.035
regulation of developmental process GO:0050793 684 0.034
cell development GO:0048468 696 0.034
oogenesis GO:0048477 229 0.034
organic cyclic compound catabolic process GO:1901361 119 0.034
rna interference GO:0016246 137 0.033
negative regulation of metabolic process GO:0009892 240 0.033
nucleoside triphosphate metabolic process GO:0009141 87 0.032
cellular component morphogenesis GO:0032989 318 0.032
molting cycle GO:0042303 281 0.032
vesicle mediated transport GO:0016192 852 0.032
regulation of nucleocytoplasmic transport GO:0046822 3 0.032
mrna metabolic process GO:0016071 31 0.032
organelle organization GO:0006996 783 0.032
response to wounding GO:0009611 4 0.031
protein metabolic process GO:0019538 422 0.030
gonad development GO:0008406 840 0.030
cytoskeleton organization GO:0007010 339 0.029
single organism behavior GO:0044708 83 0.029
cellular protein metabolic process GO:0044267 279 0.029
purine containing compound catabolic process GO:0072523 75 0.029
nucleobase containing compound metabolic process GO:0006139 406 0.028
Mouse Fly
actin filament based process GO:0030029 191 0.028
positive regulation of gtpase activity GO:0043547 28 0.028
purine ribonucleotide catabolic process GO:0009154 75 0.028
nucleoside phosphate catabolic process GO:1901292 77 0.027
cellular protein modification process GO:0006464 207 0.027
ribose phosphate metabolic process GO:0019693 99 0.027
meiotic cell cycle GO:0051321 335 0.027
regulation of response to stimulus GO:0048583 243 0.027
Fly
nucleic acid metabolic process GO:0090304 299 0.027
Mouse Fly
regulation of growth GO:0040008 409 0.026
ribonucleoside catabolic process GO:0042454 77 0.026
single organism transport GO:0044765 447 0.026
regulation of nematode larval development GO:0061062 260 0.025
glycosyl compound catabolic process GO:1901658 79 0.024
positive regulation of developmental process GO:0051094 408 0.024
regulation of developmental growth GO:0048638 389 0.024
purine nucleotide catabolic process GO:0006195 75 0.024
posttranscriptional gene silencing GO:0016441 143 0.024
regulation of chromosome organization GO:0033044 20 0.024
regulation of cytoplasmic transport GO:1903649 3 0.024
response to external biotic stimulus GO:0043207 101 0.023
ribonucleotide metabolic process GO:0009259 99 0.023
purine ribonucleotide metabolic process GO:0009150 95 0.023
ribonucleoprotein complex assembly GO:0022618 4 0.023
growth GO:0040007 562 0.023
nucleoside catabolic process GO:0009164 78 0.022
striated muscle cell development GO:0055002 157 0.022
chromosome organization GO:0051276 104 0.022
response to abiotic stimulus GO:0009628 152 0.022
Human
regulation of post embryonic development GO:0048580 260 0.022
gene silencing by rna GO:0031047 143 0.022
establishment of localization GO:0051234 1171 0.022
regulation of cell motility GO:2000145 57 0.021
mitotic g2 m transition checkpoint GO:0044818 1 0.021
muscle structure development GO:0061061 191 0.021
ribonucleoside triphosphate metabolic process GO:0009199 87 0.021
cell proliferation GO:0008283 116 0.021
purine nucleoside triphosphate catabolic process GO:0009146 72 0.020
ribonucleoside triphosphate catabolic process GO:0009203 72 0.020
ribonucleoside metabolic process GO:0009119 98 0.020
regulation of localization GO:0032879 194 0.020
regulation of chromosome segregation GO:0051983 20 0.020
negative regulation of gene expression epigenetic GO:0045814 2 0.020
carbohydrate derivative metabolic process GO:1901135 141 0.020
muscle cell differentiation GO:0042692 171 0.020
proteolysis GO:0006508 61 0.019
positive regulation of multicellular organismal process GO:0051240 417 0.019
cell cycle phase transition GO:0044770 19 0.019
secondary metabolite biosynthetic process GO:0044550 3 0.019
regulation of phosphorus metabolic process GO:0051174 81 0.019
response to other organism GO:0051707 101 0.019
purine nucleotide metabolic process GO:0006163 95 0.019
nucleoside triphosphate catabolic process GO:0009143 72 0.019
programmed cell death GO:0012501 500 0.019
regulation of transport GO:0051049 91 0.018
purine nucleoside triphosphate metabolic process GO:0009144 87 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.018
response to biotic stimulus GO:0009607 101 0.018
intracellular signal transduction GO:0035556 96 0.018
negative regulation of transcription dna templated GO:0045892 53 0.018
regulation of nucleotide catabolic process GO:0030811 35 0.018
receptor mediated endocytosis GO:0006898 715 0.018
spermatogenesis GO:0007283 41 0.018
cellular macromolecule catabolic process GO:0044265 73 0.018
carbohydrate derivative catabolic process GO:1901136 82 0.018
death GO:0016265 547 0.017
signaling GO:0023052 401 0.017
negative regulation of gene expression GO:0010629 217 0.017
regulation of vulval development GO:0040028 248 0.017
cuticle development GO:0042335 100 0.017
establishment of localization in cell GO:0051649 318 0.017
inductive cell migration GO:0040039 145 0.016
positive regulation of growth GO:0045927 369 0.016
nucleotide catabolic process GO:0009166 77 0.016
dna metabolic process GO:0006259 74 0.016
Mouse Fly
myofibril assembly GO:0030239 154 0.016
biosynthetic process GO:0009058 323 0.016
Mouse
body morphogenesis GO:0010171 620 0.016
multi organism reproductive behavior GO:0044705 387 0.016
organic substance transport GO:0071702 113 0.016
posttranscriptional regulation of gene expression GO:0010608 166 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
reproductive behavior GO:0019098 387 0.015
macromolecular complex assembly GO:0065003 193 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.015
organic substance biosynthetic process GO:1901576 323 0.015
Mouse
ribonucleotide catabolic process GO:0009261 75 0.015
epithelial cell proliferation GO:0050673 1 0.015
mitotic nuclear division GO:0007067 89 0.014
homeostatic process GO:0042592 51 0.014
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.014
behavior GO:0007610 527 0.014
oocyte differentiation GO:0009994 45 0.014
negative regulation of cell cycle GO:0045786 53 0.014
organelle localization GO:0051640 127 0.013
purine containing compound metabolic process GO:0072521 95 0.013
myosin filament organization GO:0031033 138 0.013
cell morphogenesis GO:0000902 163 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.013
localization within membrane GO:0051668 2 0.013
neuron differentiation GO:0030182 217 0.013
carbohydrate metabolic process GO:0005975 34 0.013
mitotic sister chromatid segregation GO:0000070 38 0.013
regulation of cell differentiation GO:0045595 81 0.013
myosin filament assembly GO:0031034 138 0.013
regulation of epithelial cell proliferation GO:0050678 1 0.013
cellular protein localization GO:0034613 75 0.013
organelle assembly GO:0070925 214 0.012
regulation of cellular metabolic process GO:0031323 305 0.012
Fly
macromolecular complex subunit organization GO:0043933 320 0.012
signal transduction GO:0007165 317 0.012
organelle fission GO:0048285 363 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
actin cytoskeleton organization GO:0030036 184 0.012
oocyte development GO:0048599 44 0.012
positive regulation of phosphate metabolic process GO:0045937 56 0.012
rna localization GO:0006403 3 0.012
multi organism behavior GO:0051705 389 0.012
muscle cell development GO:0055001 158 0.012
regulation of mitosis GO:0007088 18 0.012
spindle localization GO:0051653 51 0.012
gene expression GO:0010467 412 0.012
positive regulation of innate immune response GO:0045089 4 0.012
single organism biosynthetic process GO:0044711 91 0.011
Mouse
regulation of histone modification GO:0031056 1 0.011
amine metabolic process GO:0009308 15 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.011
purine nucleoside catabolic process GO:0006152 75 0.011
defense response to other organism GO:0098542 100 0.011
single organism carbohydrate metabolic process GO:0044723 29 0.011
regulation of endocytosis GO:0030100 25 0.011
cell type specific apoptotic process GO:0097285 4 0.011
positive regulation of developmental growth GO:0048639 354 0.011
cellular response to dna damage stimulus GO:0006974 41 0.010
Mouse Fly
skeletal muscle organ development GO:0060538 3 0.010
regulation of vesicle mediated transport GO:0060627 27 0.010
regulation of molecular function GO:0065009 89 0.010
phosphorus metabolic process GO:0006793 232 0.010
neuron development GO:0048666 199 0.010
regulation of purine nucleotide catabolic process GO:0033121 35 0.010
mitotic cell cycle checkpoint GO:0007093 5 0.010
chromosome separation GO:0051304 19 0.010
purine ribonucleoside catabolic process GO:0046130 75 0.010
system process GO:0003008 136 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 28 0.010
feeding behavior GO:0007631 70 0.010
regulation of chromatin modification GO:1903308 2 0.010
regulation of behavior GO:0050795 97 0.010

rev-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.053
disease of anatomical entity DOID:7 0 0.039
cancer DOID:162 0 0.028
organ system cancer DOID:0050686 0 0.023
gastrointestinal system cancer DOID:3119 0 0.020
nervous system disease DOID:863 0 0.011
reproductive organ cancer DOID:193 0 0.011
female reproductive organ cancer DOID:120 0 0.011