Caenorhabditis elegans

55 known processes

ptc-1 (CELE_ZK675.1)

Protein PTC-1

ptc-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.736
multicellular organismal reproductive process GO:0048609 815 0.702
germ cell development GO:0007281 351 0.693
sexual reproduction GO:0019953 546 0.689
embryo development ending in birth or egg hatching GO:0009792 2992 0.617
organelle organization GO:0006996 783 0.598
developmental process involved in reproduction GO:0003006 1165 0.546
multicellular organism reproduction GO:0032504 819 0.481
post embryonic development GO:0009791 2152 0.468
locomotion GO:0040011 1634 0.401
multi organism reproductive process GO:0044703 867 0.342
single organism reproductive process GO:0044702 1196 0.336
cell development GO:0048468 696 0.324
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.313
organ development GO:0048513 1102 0.302
Zebrafish Mouse Fly
transport GO:0006810 1093 0.287
axon development GO:0061564 163 0.282
Zebrafish Fly
protein metabolic process GO:0019538 422 0.215
Mouse
gamete generation GO:0007276 461 0.211
cell part morphogenesis GO:0032990 152 0.196
Zebrafish Fly
reproductive system development GO:0061458 850 0.190
Fly
nucleic acid metabolic process GO:0090304 299 0.167
death GO:0016265 547 0.164
Fly
regulation of macromolecule metabolic process GO:0060255 421 0.156
regulation of cell morphogenesis GO:0022604 40 0.147
development of primary sexual characteristics GO:0045137 840 0.146
Fly
cell cycle GO:0007049 526 0.146
Mouse Fly
catabolic process GO:0009056 318 0.145
establishment of localization GO:0051234 1171 0.134
female gamete generation GO:0007292 254 0.131
apoptotic process GO:0006915 478 0.130
Fly
regulation of cellular metabolic process GO:0031323 305 0.127
regulation of metabolic process GO:0019222 478 0.122
neuron projection development GO:0031175 187 0.120
Zebrafish Fly
gene expression GO:0010467 412 0.118
Mouse
sex differentiation GO:0007548 909 0.115
Fly
programmed cell death GO:0012501 500 0.113
Fly
hermaphrodite genitalia development GO:0040035 734 0.112
meiotic cell cycle GO:0051321 335 0.112
body morphogenesis GO:0010171 620 0.106
negative regulation of biological process GO:0048519 567 0.101
Zebrafish Mouse Fly
nucleobase containing compound metabolic process GO:0006139 406 0.101
regulation of primary metabolic process GO:0080090 292 0.098
macromolecule catabolic process GO:0009057 202 0.094
cell recognition GO:0008037 85 0.094
regulation of development heterochronic GO:0040034 18 0.094
regulation of organelle organization GO:0033043 164 0.093
multicellular organismal reproductive behavior GO:0033057 384 0.087
multicellular organismal aging GO:0010259 812 0.087
regulation of gene expression GO:0010468 366 0.086
response to chemical GO:0042221 356 0.084
Zebrafish Mouse Fly
cell division GO:0051301 262 0.084
Mouse
pattern specification process GO:0007389 59 0.082
Zebrafish Mouse
macromolecule localization GO:0033036 771 0.081
meiotic nuclear division GO:0007126 300 0.080
reproductive structure development GO:0048608 850 0.079
Fly
response to wounding GO:0009611 4 0.079
cell death GO:0008219 547 0.075
Fly
neuron projection morphogenesis GO:0048812 114 0.074
Zebrafish Fly
oogenesis GO:0048477 229 0.071
ribonucleoprotein complex assembly GO:0022618 4 0.071
neurogenesis GO:0022008 236 0.071
Zebrafish Mouse Fly
regulation of response to stimulus GO:0048583 243 0.069
Zebrafish Mouse Fly
multi organism behavior GO:0051705 389 0.068
multi organism reproductive behavior GO:0044705 387 0.067
cytoskeleton organization GO:0007010 339 0.066
cell cycle process GO:0022402 482 0.065
oviposition GO:0018991 364 0.065
regulation of biological quality GO:0065008 741 0.065
growth GO:0040007 562 0.064
Mouse Worm
maintenance of location GO:0051235 580 0.062
genitalia development GO:0048806 741 0.061
single organism signaling GO:0044700 401 0.061
Zebrafish Mouse Fly
biosynthetic process GO:0009058 323 0.061
neuron recognition GO:0008038 83 0.060
determination of adult lifespan GO:0008340 812 0.059
single organism organelle organization GO:1902589 501 0.059
regulation of developmental process GO:0050793 684 0.059
Zebrafish Mouse Worm Fly
regulation of behavior GO:0050795 97 0.058
cell morphogenesis involved in differentiation GO:0000904 112 0.056
Zebrafish Fly
positive regulation of multicellular organismal process GO:0051240 417 0.056
Worm
lipid storage GO:0019915 565 0.056
negative regulation of macromolecule metabolic process GO:0010605 229 0.054
cellular response to metal ion GO:0071248 3 0.052
embryonic body morphogenesis GO:0010172 49 0.052
ovulation GO:0030728 33 0.052
sensory organ morphogenesis GO:0090596 2 0.050
Zebrafish Fly
regulation of cellular component organization GO:0051128 248 0.050
protein localization GO:0008104 205 0.050
Mouse Fly
gonad development GO:0008406 840 0.050
Fly
regulation of multicellular organismal process GO:0051239 726 0.049
Zebrafish Mouse Worm Fly
regulation of developmental growth GO:0048638 389 0.048
Mouse Worm
cell proliferation GO:0008283 116 0.048
Mouse
regulation of biosynthetic process GO:0009889 189 0.047
neuron differentiation GO:0030182 217 0.047
Zebrafish Mouse Fly
rna metabolic process GO:0016070 228 0.046
positive regulation of developmental process GO:0051094 408 0.046
Worm
single organism localization GO:1902578 518 0.046
Fly
regulation of multicellular organismal development GO:2000026 317 0.046
Zebrafish Fly
protein complex subunit organization GO:0071822 280 0.045
organic substance biosynthetic process GO:1901576 323 0.044
cellular biosynthetic process GO:0044249 315 0.044
head development GO:0060322 1 0.043
Mouse
vesicle mediated transport GO:0016192 852 0.043
multi multicellular organism process GO:0044706 390 0.043
lipid localization GO:0010876 573 0.043
response to organic substance GO:0010033 131 0.041
Mouse
reproductive behavior GO:0019098 387 0.040
oocyte differentiation GO:0009994 45 0.040
macromolecule modification GO:0043412 218 0.039
cellular protein modification process GO:0006464 207 0.039
organelle localization GO:0051640 127 0.038
cellular protein metabolic process GO:0044267 279 0.038
muscle tissue development GO:0060537 1 0.038
regulation of rna metabolic process GO:0051252 173 0.036
negative regulation of gene expression GO:0010629 217 0.036
endocytosis GO:0006897 819 0.036
actin filament based process GO:0030029 191 0.036
behavior GO:0007610 527 0.035
negative regulation of metabolic process GO:0009892 240 0.035
response to external stimulus GO:0009605 289 0.035
Zebrafish Fly
skeletal muscle organ development GO:0060538 3 0.035
receptor mediated endocytosis GO:0006898 715 0.034
synaptic transmission GO:0007268 106 0.034
regulation of oviposition GO:0046662 43 0.033
cellular localization GO:0051641 360 0.033
Fly
macromolecule biosynthetic process GO:0009059 250 0.033
organic cyclic compound biosynthetic process GO:1901362 195 0.032
divalent inorganic cation transport GO:0072511 17 0.032
heterocycle catabolic process GO:0046700 119 0.032
regionalization GO:0003002 31 0.031
Zebrafish Mouse
gene silencing GO:0016458 143 0.031
regulation of meiotic cell cycle GO:0051445 136 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.030
positive regulation of developmental growth GO:0048639 354 0.030
Worm
rna interference GO:0016246 137 0.030
divalent metal ion transport GO:0070838 17 0.030
gene silencing by rna GO:0031047 143 0.030
protein modification by small protein conjugation or removal GO:0070647 40 0.030
protein modification process GO:0036211 207 0.029
signal transduction GO:0007165 317 0.029
Zebrafish Mouse Fly
digestive tract development GO:0048565 122 0.029
posttranscriptional regulation of gene expression GO:0010608 166 0.029
organic substance catabolic process GO:1901575 294 0.029
negative regulation of cellular process GO:0048523 239 0.029
Zebrafish Mouse Fly
cell morphogenesis GO:0000902 163 0.028
Zebrafish Fly
male gamete generation GO:0048232 41 0.028
organelle fission GO:0048285 363 0.027
establishment of organelle localization GO:0051656 123 0.027
cell fate commitment GO:0045165 139 0.027
Fly
regulation of cell cycle GO:0051726 194 0.027
Mouse Fly
regulation of multicellular organism growth GO:0040014 373 0.027
Mouse Worm
regulation of nuclear division GO:0051783 115 0.027
developmental growth GO:0048589 412 0.026
Mouse Worm
regulation of gene expression epigenetic GO:0040029 163 0.026
molting cycle GO:0042303 281 0.026
cellular response to chemical stimulus GO:0070887 129 0.026
Mouse
nervous system development GO:0007399 253 0.025
Zebrafish Mouse Fly
cell migration GO:0016477 306 0.025
Fly
epidermal cell fate specification GO:0009957 5 0.025
regulation of localization GO:0032879 194 0.025
Mouse Fly
cellular component assembly GO:0022607 293 0.025
microtubule based process GO:0007017 182 0.024
cell substrate adhesion GO:0031589 1 0.024
cellular response to stress GO:0033554 162 0.024
macromolecular complex subunit organization GO:0043933 320 0.024
establishment of localization in cell GO:0051649 318 0.024
Fly
posttranscriptional gene silencing GO:0016441 143 0.024
chromosome segregation GO:0007059 180 0.024
cellular response to organic substance GO:0071310 119 0.023
Mouse
secretion by cell GO:0032940 138 0.023
meiotic cell cycle process GO:1903046 170 0.023
regulation of nitrogen compound metabolic process GO:0051171 222 0.023
cellular component movement GO:0006928 388 0.023
Zebrafish Fly
localization of cell GO:0051674 313 0.023
Fly
positive regulation of neuron differentiation GO:0045666 4 0.023
aging GO:0007568 812 0.023
muscle structure development GO:0061061 191 0.022
Zebrafish
collagen and cuticulin based cuticle development GO:0040002 99 0.022
positive regulation of multicellular organism growth GO:0040018 352 0.022
Worm
transcription from rna polymerase ii promoter GO:0006366 149 0.021
spermatogenesis GO:0007283 41 0.021
heterocycle biosynthetic process GO:0018130 187 0.021
intracellular receptor signaling pathway GO:0030522 2 0.021
rna processing GO:0006396 34 0.021
regulation of growth GO:0040008 409 0.021
Mouse Worm
regulation of macromolecule biosynthetic process GO:0010556 189 0.021
vulval development GO:0040025 333 0.021
signaling GO:0023052 401 0.021
Zebrafish Mouse Fly
response to acid chemical GO:0001101 4 0.020
Mouse
axonal fasciculation GO:0007413 79 0.020
organic cyclic compound catabolic process GO:1901361 119 0.020
protein modification by small protein conjugation GO:0032446 31 0.020
single organism cellular localization GO:1902580 72 0.020
Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.020
negative regulation of cellular metabolic process GO:0031324 95 0.020
regulation of protein metabolic process GO:0051246 81 0.019
cellular macromolecule biosynthetic process GO:0034645 247 0.019
chemotaxis GO:0006935 120 0.019
Zebrafish Fly
nematode male tail tip morphogenesis GO:0045138 77 0.019
regulation of cell proliferation GO:0042127 105 0.019
Mouse
digestive system development GO:0055123 122 0.019
striated muscle cell differentiation GO:0051146 158 0.019
regulation of cell cycle process GO:0010564 145 0.019
negative regulation of developmental process GO:0051093 227 0.019
Zebrafish Mouse
generation of neurons GO:0048699 235 0.019
Zebrafish Mouse Fly
protein transmembrane transport GO:0071806 4 0.018
regulation of cytoplasmic transport GO:1903649 3 0.018
Fly
glycoprotein metabolic process GO:0009100 29 0.018
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.018
actomyosin structure organization GO:0031032 154 0.018
oocyte development GO:0048599 44 0.018
positive regulation of chromosome organization GO:2001252 2 0.018
pre mirna processing GO:0031054 3 0.018
actin cytoskeleton organization GO:0030036 184 0.018
regulation of canonical wnt signaling pathway GO:0060828 1 0.017
regulation of cell communication GO:0010646 176 0.017
Zebrafish Mouse Fly
nucleobase containing compound catabolic process GO:0034655 114 0.017
defense response GO:0006952 296 0.017
cell cell signaling GO:0007267 118 0.017
lamellipodium organization GO:0097581 2 0.017
tissue development GO:0009888 112 0.017
Zebrafish Mouse
cell motility GO:0048870 313 0.017
Fly
gastrulation GO:0007369 58 0.017
positive regulation of growth GO:0045927 369 0.017
Worm
post embryonic organ development GO:0048569 336 0.017
Fly
regulation of cytoskeleton organization GO:0051493 41 0.017
intracellular protein transmembrane transport GO:0065002 4 0.017
regulation of cell differentiation GO:0045595 81 0.017
cuticle development GO:0042335 100 0.017
cation transport GO:0006812 78 0.016
male anatomical structure morphogenesis GO:0090598 78 0.016
organelle fusion GO:0048284 8 0.016
cell projection morphogenesis GO:0048858 148 0.016
Zebrafish Fly
neuron development GO:0048666 199 0.016
Zebrafish Fly
regulation of cellular protein metabolic process GO:0032268 75 0.016
positive regulation of cellular component organization GO:0051130 34 0.016
response to dsrna GO:0043331 10 0.016
positive regulation of catalytic activity GO:0043085 59 0.016
myofibril assembly GO:0030239 154 0.016
protein catabolic process GO:0030163 162 0.016
neuron projection extension GO:1990138 37 0.016
striated muscle cell development GO:0055002 157 0.016
cellular macromolecular complex assembly GO:0034622 184 0.016
meiotic chromosome segregation GO:0045132 139 0.015
response to temperature stimulus GO:0009266 66 0.015
peptidyl lysine acetylation GO:0018394 3 0.015
response to heat GO:0009408 50 0.015
regulation of axonogenesis GO:0050770 24 0.015
embryonic morphogenesis GO:0048598 152 0.015
Mouse
formation of anatomical boundary GO:0048859 1 0.015
tissue morphogenesis GO:0048729 65 0.015
Zebrafish Mouse
striated muscle myosin thick filament assembly GO:0071688 138 0.015
internal peptidyl lysine acetylation GO:0018393 3 0.015
protein oligomerization GO:0051259 4 0.014
lamellipodium assembly GO:0030032 2 0.014
regulation of cell division GO:0051302 142 0.014
Mouse
establishment of protein localization GO:0045184 50 0.014
Fly
chromosome organization involved in meiosis GO:0070192 25 0.014
cell projection organization GO:0030030 231 0.014
Zebrafish Fly
positive regulation of organ growth GO:0046622 4 0.014
bmp signaling pathway GO:0030509 3 0.014
nucleic acid templated transcription GO:0097659 169 0.014
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
female meiotic division GO:0007143 17 0.014
regulation of response to wounding GO:1903034 1 0.014
rna catabolic process GO:0006401 21 0.014
feminization of hermaphroditic germ line GO:0040022 34 0.014
establishment of spindle localization GO:0051293 51 0.014
single organism transport GO:0044765 447 0.013
Fly
regulation of locomotion GO:0040012 161 0.013
Fly
regulation of organ morphogenesis GO:2000027 4 0.013
axis specification GO:0009798 23 0.013
Mouse
posttranscriptional gene silencing by rna GO:0035194 143 0.013
positive regulation of response to external stimulus GO:0032103 6 0.013
cellular catabolic process GO:0044248 199 0.013
regulation of reproductive process GO:2000241 66 0.013
regulation of bmp signaling pathway GO:0030510 3 0.013
response to abiotic stimulus GO:0009628 152 0.013
anatomical structure formation involved in morphogenesis GO:0048646 250 0.013
Mouse
muscle cell development GO:0055001 158 0.013
secretion GO:0046903 147 0.013
ion transport GO:0006811 113 0.013
regulation of protein import into nucleus GO:0042306 3 0.013
Fly
muscle organ development GO:0007517 26 0.013
Zebrafish
cytoskeleton dependent cytokinesis GO:0061640 35 0.013
transmembrane transport GO:0055085 110 0.013
synaptonemal complex assembly GO:0007130 6 0.013
positive regulation of cell fate commitment GO:0010455 1 0.013
organic substance transport GO:0071702 113 0.013
Fly
regulation of meiosis GO:0040020 94 0.012
synaptic vesicle recycling GO:0036465 3 0.012
cellular nitrogen compound biosynthetic process GO:0044271 192 0.012
single fertilization GO:0007338 61 0.012
detection of external stimulus GO:0009581 4 0.012
positive regulation of neurogenesis GO:0050769 4 0.012
cellular component biogenesis GO:0044085 297 0.012
myosin filament assembly GO:0031034 138 0.012
system process GO:0003008 136 0.012
single organism catabolic process GO:0044712 129 0.012
male sex differentiation GO:0046661 86 0.012
cell cell junction assembly GO:0007043 2 0.012
organelle assembly GO:0070925 214 0.012
myosin filament organization GO:0031033 138 0.012
macromolecular complex assembly GO:0065003 193 0.012
cellular component morphogenesis GO:0032989 318 0.012
Zebrafish Fly
taxis GO:0042330 128 0.011
Zebrafish Fly
regulation of cell migration GO:0030334 55 0.011
Fly
ion transmembrane transport GO:0034220 91 0.011
internal protein amino acid acetylation GO:0006475 3 0.011
detection of abiotic stimulus GO:0009582 4 0.011
proteolysis GO:0006508 61 0.011
response to external biotic stimulus GO:0043207 101 0.011
positive regulation of catabolic process GO:0009896 38 0.011
regulation of protein targeting GO:1903533 3 0.011
Fly
regulation of cell motility GO:2000145 57 0.011
Fly
organonitrogen compound metabolic process GO:1901564 151 0.011
pigment metabolic process GO:0042440 2 0.011
intracellular protein transmembrane import GO:0044743 3 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.011
Zebrafish Fly
oocyte axis specification GO:0007309 2 0.011
apical junction assembly GO:0043297 1 0.011
phosphate containing compound metabolic process GO:0006796 232 0.010
regulation of kinase activity GO:0043549 29 0.010
mitotic nuclear division GO:0007067 89 0.010
negative regulation of post embryonic development GO:0048581 208 0.010
secondary metabolic process GO:0019748 3 0.010
cellular response to inorganic substance GO:0071241 3 0.010
meiosis i GO:0007127 19 0.010
pharynx development GO:0060465 51 0.010
small molecule metabolic process GO:0044281 186 0.010
regulation of cellular biosynthetic process GO:0031326 189 0.010
cytokinesis GO:0000910 80 0.010
phosphorus metabolic process GO:0006793 232 0.010
dsrna fragmentation GO:0031050 10 0.010
regulation of cell shape GO:0008360 6 0.010
actin filament based movement GO:0030048 4 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010

ptc-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041