Caenorhabditis elegans

72 known processes

exc-7 (CELE_F35H8.5)

Protein EXC-7

exc-7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gene expression GO:0010467 412 0.460
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.392
Fly
rna metabolic process GO:0016070 228 0.363
oviposition GO:0018991 364 0.355
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.353
multi organism reproductive behavior GO:0044705 387 0.344
regulation of gene expression GO:0010468 366 0.312
embryo development ending in birth or egg hatching GO:0009792 2992 0.300
single organism signaling GO:0044700 401 0.284
regulation of developmental process GO:0050793 684 0.282
regulation of rna metabolic process GO:0051252 173 0.246
multi organism behavior GO:0051705 389 0.241
multicellular organismal reproductive behavior GO:0033057 384 0.235
sexual reproduction GO:0019953 546 0.230
Fly
embryo development GO:0009790 3052 0.229
post embryonic development GO:0009791 2152 0.229
death GO:0016265 547 0.208
regulation of metabolic process GO:0019222 478 0.206
developmental growth GO:0048589 412 0.201
locomotion GO:0040011 1634 0.196
cell development GO:0048468 696 0.193
multi multicellular organism process GO:0044706 390 0.193
regulation of multicellular organismal development GO:2000026 317 0.192
programmed cell death GO:0012501 500 0.185
positive regulation of cellular process GO:0048522 332 0.183
Human Mouse Rat
multicellular organismal aging GO:0010259 812 0.181
regulation of cell differentiation GO:0045595 81 0.173
germ cell development GO:0007281 351 0.167
Fly
female gamete generation GO:0007292 254 0.166
Fly
regulation of nitrogen compound metabolic process GO:0051171 222 0.164
regulation of cellular metabolic process GO:0031323 305 0.161
regulation of cell communication GO:0010646 176 0.157
neurogenesis GO:0022008 236 0.157
cell cycle GO:0007049 526 0.156
cell death GO:0008219 547 0.154
nucleic acid metabolic process GO:0090304 299 0.151
generation of neurons GO:0048699 235 0.150
behavior GO:0007610 527 0.147
Mouse
reproductive behavior GO:0019098 387 0.146
multi organism reproductive process GO:0044703 867 0.145
Fly
post embryonic organ development GO:0048569 336 0.143
negative regulation of nematode larval development GO:0061064 208 0.143
multicellular organism growth GO:0035264 385 0.141
oogenesis GO:0048477 229 0.139
Fly
aging GO:0007568 812 0.135
establishment of localization GO:0051234 1171 0.134
regulation of multicellular organismal process GO:0051239 726 0.133
regulation of growth GO:0040008 409 0.133
positive regulation of cell communication GO:0010647 69 0.131
regulation of macromolecule metabolic process GO:0060255 421 0.131
cellular biosynthetic process GO:0044249 315 0.130
Human Mouse
regulation of developmental growth GO:0048638 389 0.125
regulation of biological quality GO:0065008 741 0.120
signaling GO:0023052 401 0.115
embryonic morphogenesis GO:0048598 152 0.110
regulation of multicellular organism growth GO:0040014 373 0.108
positive regulation of signaling GO:0023056 66 0.108
growth GO:0040007 562 0.106
receptor mediated endocytosis GO:0006898 715 0.103
determination of adult lifespan GO:0008340 812 0.100
negative regulation of gene expression GO:0010629 217 0.098
negative regulation of macromolecule metabolic process GO:0010605 229 0.098
gamete generation GO:0007276 461 0.097
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.096
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.095
organic substance biosynthetic process GO:1901576 323 0.093
Human Mouse
organ development GO:0048513 1102 0.092
cell migration GO:0016477 306 0.091
positive regulation of growth GO:0045927 369 0.090
negative regulation of cellular process GO:0048523 239 0.089
Mouse
mrna metabolic process GO:0016071 31 0.089
positive regulation of multicellular organism growth GO:0040018 352 0.087
regulation of nematode larval development GO:0061062 260 0.086
apoptotic process GO:0006915 478 0.086
positive regulation of developmental growth GO:0048639 354 0.085
positive regulation of multicellular organismal process GO:0051240 417 0.084
Zebrafish Rat
regulation of rna splicing GO:0043484 7 0.084
cell motility GO:0048870 313 0.083
nervous system development GO:0007399 253 0.083
negative regulation of vulval development GO:0040027 206 0.081
synaptic transmission GO:0007268 106 0.081
negative regulation of biological process GO:0048519 567 0.080
Mouse
body morphogenesis GO:0010171 620 0.080
neuron differentiation GO:0030182 217 0.079
single organism reproductive process GO:0044702 1196 0.077
Fly
developmental process involved in reproduction GO:0003006 1165 0.077
Fly
regulation of cell cycle GO:0051726 194 0.076
establishment of localization in cell GO:0051649 318 0.075
mesodermal cell migration GO:0008078 9 0.075
regulation of synaptic transmission GO:0050804 34 0.072
regulation of signaling GO:0023051 172 0.071
positive regulation of developmental process GO:0051094 408 0.070
Zebrafish Rat
negative regulation of metabolic process GO:0009892 240 0.069
cellular component assembly GO:0022607 293 0.069
rna splicing GO:0008380 8 0.068
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.066
Mouse
regulation of macromolecule biosynthetic process GO:0010556 189 0.065
Human Mouse
vesicle mediated transport GO:0016192 852 0.063
system process GO:0003008 136 0.063
Mouse
sex differentiation GO:0007548 909 0.062
transport GO:0006810 1093 0.061
organelle organization GO:0006996 783 0.061
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.060
ribonucleoprotein complex assembly GO:0022618 4 0.060
multicellular organismal reproductive process GO:0048609 815 0.059
Fly
positive regulation of synaptic transmission GO:0050806 24 0.058
aromatic compound biosynthetic process GO:0019438 192 0.058
nucleobase containing compound biosynthetic process GO:0034654 184 0.056
sensory organ morphogenesis GO:0090596 2 0.056
vulval development GO:0040025 333 0.055
organic cyclic compound biosynthetic process GO:1901362 195 0.055
cellular localization GO:0051641 360 0.055
endocytosis GO:0006897 819 0.054
single organism organelle organization GO:1902589 501 0.054
macromolecule localization GO:0033036 771 0.054
secretion by cell GO:0032940 138 0.054
regulation of locomotion GO:0040012 161 0.054
nucleobase containing compound metabolic process GO:0006139 406 0.053
lipid biosynthetic process GO:0008610 28 0.053
maintenance of location GO:0051235 580 0.052
cell cycle process GO:0022402 482 0.051
lipid localization GO:0010876 573 0.051
regulation of cellular component organization GO:0051128 248 0.051
Rat
cellular macromolecule biosynthetic process GO:0034645 247 0.051
Human Mouse
localization of cell GO:0051674 313 0.050
negative regulation of post embryonic development GO:0048581 208 0.050
cell division GO:0051301 262 0.049
lipid storage GO:0019915 565 0.048
regulation of nervous system development GO:0051960 41 0.047
biosynthetic process GO:0009058 323 0.046
Human Mouse
cell fate commitment GO:0045165 139 0.046
regulation of vulval development GO:0040028 248 0.046
signal transduction GO:0007165 317 0.046
regulation of cell development GO:0060284 49 0.046
phosphorus metabolic process GO:0006793 232 0.045
regulation of signal transduction GO:0009966 135 0.045
rna splicing via transesterification reactions GO:0000375 8 0.044
collagen and cuticulin based cuticle development GO:0040002 99 0.044
cellular protein metabolic process GO:0044267 279 0.044
Human Mouse
macromolecule biosynthetic process GO:0009059 250 0.042
Human Mouse
negative regulation of rna metabolic process GO:0051253 53 0.041
cellular component movement GO:0006928 388 0.041
cuticle development GO:0042335 100 0.041
organ morphogenesis GO:0009887 67 0.040
regulation of neuron projection development GO:0010975 31 0.040
Rat
axon development GO:0061564 163 0.040
organelle fission GO:0048285 363 0.039
secretion GO:0046903 147 0.038
negative regulation of developmental process GO:0051093 227 0.038
Mouse
protein metabolic process GO:0019538 422 0.038
Human Mouse
cell cell signaling GO:0007267 118 0.038
positive regulation of gene expression GO:0010628 112 0.038
Human Mouse
regulation of primary metabolic process GO:0080090 292 0.037
male gamete generation GO:0048232 41 0.037
ras protein signal transduction GO:0007265 31 0.037
regulation of mrna splicing via spliceosome GO:0048024 7 0.036
regulation of post embryonic development GO:0048580 260 0.036
catabolic process GO:0009056 318 0.036
negative regulation of multicellular organismal process GO:0051241 236 0.035
cellular component biogenesis GO:0044085 297 0.035
g protein coupled receptor signaling pathway GO:0007186 46 0.035
head development GO:0060322 1 0.035
cellular macromolecular complex assembly GO:0034622 184 0.035
single organism localization GO:1902578 518 0.034
nuclear migration GO:0007097 54 0.034
phosphate containing compound metabolic process GO:0006796 232 0.033
positive regulation of metabolic process GO:0009893 187 0.033
Human Mouse
cell surface receptor signaling pathway GO:0007166 149 0.033
neuron neuron synaptic transmission GO:0007270 22 0.033
cell projection morphogenesis GO:0048858 148 0.033
Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.033
Human Mouse Rat
response to chemical GO:0042221 356 0.032
cytoskeleton organization GO:0007010 339 0.032
response to external stimulus GO:0009605 289 0.032
organic substance catabolic process GO:1901575 294 0.031
regulation of nucleocytoplasmic transport GO:0046822 3 0.031
organophosphate metabolic process GO:0019637 125 0.031
heterocycle biosynthetic process GO:0018130 187 0.031
regulation of transcription dna templated GO:0006355 164 0.031
developmental growth involved in morphogenesis GO:0060560 37 0.030
protein modification process GO:0036211 207 0.030
organophosphate catabolic process GO:0046434 81 0.030
meiotic cell cycle GO:0051321 335 0.030
chemotaxis GO:0006935 120 0.030
neuron projection guidance GO:0097485 82 0.030
single organism transport GO:0044765 447 0.029
neuron projection development GO:0031175 187 0.029
Mouse Rat
cellular component morphogenesis GO:0032989 318 0.029
Mouse
protein complex subunit organization GO:0071822 280 0.028
transcription from rna polymerase ii promoter GO:0006366 149 0.028
negative regulation of cellular metabolic process GO:0031324 95 0.028
cellular catabolic process GO:0044248 199 0.028
protein phosphorylation GO:0006468 85 0.027
regulation of meiotic cell cycle GO:0051445 136 0.027
inductive cell migration GO:0040039 145 0.027
fertilization GO:0009566 63 0.027
developmental cell growth GO:0048588 39 0.026
regulation of rna biosynthetic process GO:2001141 165 0.026
rna biosynthetic process GO:0032774 169 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.026
axon guidance GO:0007411 82 0.026
protein localization GO:0008104 205 0.026
neuron development GO:0048666 199 0.026
Mouse Rat
regulation of cytoplasmic transport GO:1903649 3 0.026
positive regulation of macromolecule metabolic process GO:0010604 149 0.026
Human Mouse
positive regulation of signal transduction GO:0009967 40 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.026
regulation of organelle organization GO:0033043 164 0.026
molting cycle GO:0042303 281 0.025
macromolecular complex subunit organization GO:0043933 320 0.025
genitalia development GO:0048806 741 0.025
skeletal muscle organ development GO:0060538 3 0.025
transcription dna templated GO:0006351 168 0.025
regulation of protein targeting GO:1903533 3 0.025
negative regulation of cellular biosynthetic process GO:0031327 65 0.024
macromolecule modification GO:0043412 218 0.024
single fertilization GO:0007338 61 0.024
regulation of neurogenesis GO:0050767 40 0.024
adult behavior GO:0030534 3 0.024
regulation of apoptotic signaling pathway GO:2001233 1 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.024
multicellular organism reproduction GO:0032504 819 0.024
Fly
regulation of neuron differentiation GO:0045664 40 0.024
taxis GO:0042330 128 0.023
nematode male tail tip morphogenesis GO:0045138 77 0.023
reproductive structure development GO:0048608 850 0.023
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.023
nucleus localization GO:0051647 55 0.023
striated muscle contraction involved in embryonic body morphogenesis GO:0061199 13 0.022
regulation of response to stimulus GO:0048583 243 0.022
establishment of nucleus localization GO:0040023 55 0.022
axonal fasciculation GO:0007413 79 0.022
nucleic acid templated transcription GO:0097659 169 0.021
negative regulation of cell cycle GO:0045786 53 0.021
organic substance transport GO:0071702 113 0.021
regulation of catabolic process GO:0009894 57 0.021
muscle contraction GO:0006936 43 0.021
membrane depolarization GO:0051899 1 0.021
nucleobase containing small molecule metabolic process GO:0055086 115 0.021
regulation of cell cycle process GO:0010564 145 0.020
synaptic transmission cholinergic GO:0007271 21 0.020
neuron recognition GO:0008038 83 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.020
positive regulation of vulval development GO:0040026 52 0.020
regulation of alternative mrna splicing via spliceosome GO:0000381 7 0.020
cellular protein modification process GO:0006464 207 0.019
pronuclear migration GO:0035046 51 0.019
intracellular signal transduction GO:0035556 96 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
Zebrafish
striated muscle contraction GO:0006941 17 0.019
small molecule metabolic process GO:0044281 186 0.019
cell recognition GO:0008037 85 0.019
myofibril assembly GO:0030239 154 0.019
digestive tract development GO:0048565 122 0.019
organelle assembly GO:0070925 214 0.019
male sex differentiation GO:0046661 86 0.018
adult locomotory behavior GO:0008344 1 0.018
organelle localization GO:0051640 127 0.018
actin cytoskeleton organization GO:0030036 184 0.018
establishment of cell polarity GO:0030010 46 0.018
regulation of organ morphogenesis GO:2000027 4 0.018
mitotic cell cycle process GO:1903047 194 0.018
positive regulation of neuron differentiation GO:0045666 4 0.018
Rat
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 8 0.018
nucleoside phosphate metabolic process GO:0006753 108 0.018
macromolecular complex assembly GO:0065003 193 0.018
regulation of cellular biosynthetic process GO:0031326 189 0.018
Human Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.018
Human Mouse
monocarboxylic acid biosynthetic process GO:0072330 13 0.018
carboxylic acid biosynthetic process GO:0046394 21 0.018
positive regulation of neurogenesis GO:0050769 4 0.017
Rat
positive regulation of cell cycle GO:0045787 55 0.017
establishment of organelle localization GO:0051656 123 0.017
positive regulation of intracellular transport GO:0032388 2 0.017
meiotic chromosome segregation GO:0045132 139 0.017
regulation of meiosis GO:0040020 94 0.017
development of primary male sexual characteristics GO:0046546 4 0.017
regulation of cell size GO:0008361 30 0.017
dendrite development GO:0016358 42 0.017
Mouse Rat
axonogenesis GO:0007409 102 0.017
purine containing compound metabolic process GO:0072521 95 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.016
ribonucleotide metabolic process GO:0009259 99 0.016
tube development GO:0035295 126 0.016
striated muscle cell differentiation GO:0051146 158 0.016
hermaphrodite genitalia development GO:0040035 734 0.016
neuron projection extension GO:1990138 37 0.016
positive regulation of cellular metabolic process GO:0031325 178 0.016
Human Mouse
negative regulation of neurogenesis GO:0050768 4 0.016
purine nucleoside triphosphate metabolic process GO:0009144 87 0.016
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.016
carbohydrate derivative metabolic process GO:1901135 141 0.016
mitotic nuclear division GO:0007067 89 0.016
regulation of axonogenesis GO:0050770 24 0.016
positive regulation of protein transport GO:0051222 4 0.015
meiotic cell cycle process GO:1903046 170 0.015
positive regulation of neuron projection development GO:0010976 4 0.015
Rat
golgi vesicle transport GO:0048193 3 0.015
detection of external stimulus GO:0009581 4 0.015
neuron projection morphogenesis GO:0048812 114 0.015
Mouse
regulation of extent of cell growth GO:0061387 20 0.015
cellular nitrogen compound biosynthetic process GO:0044271 192 0.015
single organism catabolic process GO:0044712 129 0.015
chromosome segregation GO:0007059 180 0.015
regulation of cellular component size GO:0032535 40 0.015
cellular lipid metabolic process GO:0044255 40 0.015
regulation of transport GO:0051049 91 0.015
mrna splicing via spliceosome GO:0000398 8 0.015
small gtpase mediated signal transduction GO:0007264 32 0.015
regulation of protein import into nucleus GO:0042306 3 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.015
cell projection organization GO:0030030 231 0.015
Mouse Rat
response to extracellular stimulus GO:0009991 38 0.014
single organism behavior GO:0044708 83 0.014
Mouse
lipid metabolic process GO:0006629 77 0.014
response to wounding GO:0009611 4 0.014
single organism biosynthetic process GO:0044711 91 0.014
pigmentation GO:0043473 2 0.014
defense response GO:0006952 296 0.014
regulation of synaptic transmission cholinergic GO:0032222 7 0.014
macromolecule catabolic process GO:0009057 202 0.014
positive regulation of meiotic cell cycle GO:0051446 47 0.014
purine nucleotide metabolic process GO:0006163 95 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.014
cyclic purine nucleotide metabolic process GO:0052652 2 0.014
digestive tract morphogenesis GO:0048546 76 0.014
negative regulation of gene expression epigenetic GO:0045814 2 0.014
cellular protein complex assembly GO:0043623 178 0.014
muscle attachment GO:0016203 3 0.014
male anatomical structure morphogenesis GO:0090598 78 0.014
regulation of cellular localization GO:0060341 42 0.013
digestive system development GO:0055123 122 0.013
purine ribonucleoside metabolic process GO:0046128 92 0.013
regulation of mitotic cell cycle GO:0007346 76 0.013
cell morphogenesis GO:0000902 163 0.013
Mouse
regulation of cellular catabolic process GO:0031329 51 0.013
gonad development GO:0008406 840 0.013
muscle system process GO:0003012 43 0.013
cell morphogenesis involved in differentiation GO:0000904 112 0.013
Mouse
actin filament based process GO:0030029 191 0.013
protein catabolic process GO:0030163 162 0.013
ribose phosphate metabolic process GO:0019693 99 0.013
regulation of nucleic acid templated transcription GO:1903506 165 0.013
membrane invagination GO:0010324 98 0.013
mechanosensory behavior GO:0007638 25 0.013
carboxylic acid metabolic process GO:0019752 34 0.012
negative regulation of locomotion GO:0040013 21 0.012
regulation of cell projection organization GO:0031344 38 0.012
Rat
muscle tissue development GO:0060537 1 0.012
ectoderm development GO:0007398 3 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
Human Mouse
dna templated transcription elongation GO:0006354 1 0.012
organonitrogen compound metabolic process GO:1901564 151 0.012
reproductive system development GO:0061458 850 0.012
response to bacterium GO:0009617 86 0.012
detection of abiotic stimulus GO:0009582 4 0.012
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 2 0.012
spindle organization GO:0007051 92 0.012
positive regulation of catabolic process GO:0009896 38 0.012
embryonic body morphogenesis GO:0010172 49 0.012
gtp catabolic process GO:0006184 46 0.012
phagocytosis engulfment GO:0006911 98 0.012
ribonucleoprotein complex biogenesis GO:0022613 8 0.012
rna localization GO:0006403 3 0.012
cell type specific apoptotic process GO:0097285 4 0.012
membrane organization GO:0061024 135 0.012
regulation of nuclear division GO:0051783 115 0.011
glycosyl compound metabolic process GO:1901657 100 0.011
regulation of protein localization GO:0032880 50 0.011
regulation of axon extension GO:0030516 20 0.011
myosin filament organization GO:0031033 138 0.011
single organism cellular localization GO:1902580 72 0.011
single organism intracellular transport GO:1902582 70 0.011
rna interference GO:0016246 137 0.011
mrna processing GO:0006397 13 0.011
regulation of cell division GO:0051302 142 0.011
neuromuscular junction development GO:0007528 2 0.011
carbohydrate derivative catabolic process GO:1901136 82 0.011
gene silencing by rna GO:0031047 143 0.011
regulation of bmp signaling pathway GO:0030510 3 0.011
cell growth GO:0016049 44 0.011
neurological system process GO:0050877 53 0.011
Mouse
single organism carbohydrate metabolic process GO:0044723 29 0.011
development of primary sexual characteristics GO:0045137 840 0.011
tissue morphogenesis GO:0048729 65 0.011
regulation of anatomical structure morphogenesis GO:0022603 51 0.011
Zebrafish
apoptotic cell clearance GO:0043277 111 0.011
positive regulation of biosynthetic process GO:0009891 109 0.011
Human Mouse
regulation of phosphate metabolic process GO:0019220 81 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.010
protein complex biogenesis GO:0070271 186 0.010
nucleotide metabolic process GO:0009117 108 0.010
negative regulation of mitotic cell cycle GO:0045930 42 0.010
cell proliferation GO:0008283 116 0.010
Fly
rna processing GO:0006396 34 0.010
cellular component assembly involved in morphogenesis GO:0010927 183 0.010
regulation of endocytosis GO:0030100 25 0.010
negative regulation of neuron differentiation GO:0045665 4 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.010
cell substrate adhesion GO:0031589 1 0.010
phosphorylation GO:0016310 116 0.010
canonical wnt signaling pathway GO:0060070 3 0.010
nucleobase containing compound catabolic process GO:0034655 114 0.010
regulation of biosynthetic process GO:0009889 189 0.010
Human Mouse
myosin filament assembly GO:0031034 138 0.010

exc-7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
nervous system disease DOID:863 0 0.015
gastrointestinal system cancer DOID:3119 0 0.011
musculoskeletal system disease DOID:17 0 0.011