Caenorhabditis elegans

10 known processes

acl-14 (CELE_K07B1.5)

Protein ACL-14

acl-14 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multicellular organism reproduction GO:0032504 819 0.685
multi organism reproductive process GO:0044703 867 0.603
single organism localization GO:1902578 518 0.463
embryo development GO:0009790 3052 0.417
single organism transport GO:0044765 447 0.308
locomotion GO:0040011 1634 0.303
secretion by cell GO:0032940 138 0.302
post embryonic development GO:0009791 2152 0.282
establishment of localization in cell GO:0051649 318 0.280
developmental process involved in reproduction GO:0003006 1165 0.276
secretion GO:0046903 147 0.275
embryo development ending in birth or egg hatching GO:0009792 2992 0.270
multicellular organismal reproductive process GO:0048609 815 0.262
cellular component assembly GO:0022607 293 0.249
anatomical structure formation involved in morphogenesis GO:0048646 250 0.248
organelle organization GO:0006996 783 0.229
vesicle mediated transport GO:0016192 852 0.226
single organism organelle organization GO:1902589 501 0.224
organ development GO:0048513 1102 0.221
gene expression GO:0010467 412 0.217
single organism reproductive process GO:0044702 1196 0.207
signaling GO:0023052 401 0.202
protein metabolic process GO:0019538 422 0.201
cell death GO:0008219 547 0.189
nucleobase containing small molecule metabolic process GO:0055086 115 0.181
cellular component biogenesis GO:0044085 297 0.180
apoptotic process GO:0006915 478 0.180
multicellular organismal aging GO:0010259 812 0.174
regulation of signaling GO:0023051 172 0.172
aging GO:0007568 812 0.168
establishment of localization GO:0051234 1171 0.163
cellular component movement GO:0006928 388 0.162
endocytosis GO:0006897 819 0.151
cell surface receptor signaling pathway GO:0007166 149 0.149
macromolecule localization GO:0033036 771 0.148
Worm
nucleobase containing compound metabolic process GO:0006139 406 0.147
death GO:0016265 547 0.137
embryonic morphogenesis GO:0048598 152 0.132
determination of adult lifespan GO:0008340 812 0.123
transport GO:0006810 1093 0.122
sexual reproduction GO:0019953 546 0.117
negative regulation of biological process GO:0048519 567 0.116
regulation of multicellular organismal process GO:0051239 726 0.114
reproductive behavior GO:0019098 387 0.114
ribonucleoside triphosphate metabolic process GO:0009199 87 0.114
biosynthetic process GO:0009058 323 0.113
behavior GO:0007610 527 0.112
oviposition GO:0018991 364 0.111
macromolecular complex subunit organization GO:0043933 320 0.111
regulation of localization GO:0032879 194 0.109
protein localization GO:0008104 205 0.106
single organism signaling GO:0044700 401 0.106
reproductive system development GO:0061458 850 0.102
multi multicellular organism process GO:0044706 390 0.101
localization of cell GO:0051674 313 0.099
purine ribonucleotide metabolic process GO:0009150 95 0.096
ribonucleotide metabolic process GO:0009259 99 0.094
organic substance catabolic process GO:1901575 294 0.093
multicellular organismal reproductive behavior GO:0033057 384 0.093
response to chemical GO:0042221 356 0.092
multi organism reproductive behavior GO:0044705 387 0.091
cellular component morphogenesis GO:0032989 318 0.085
small molecule metabolic process GO:0044281 186 0.085
hermaphrodite genitalia development GO:0040035 734 0.084
signal transduction GO:0007165 317 0.084
response to external stimulus GO:0009605 289 0.083
cell development GO:0048468 696 0.081
programmed cell death GO:0012501 500 0.081
striated muscle cell differentiation GO:0051146 158 0.079
cellular protein modification process GO:0006464 207 0.079
macromolecule biosynthetic process GO:0009059 250 0.079
cellular protein complex assembly GO:0043623 178 0.078
protein complex subunit organization GO:0071822 280 0.076
organonitrogen compound metabolic process GO:1901564 151 0.075
regulation of response to stimulus GO:0048583 243 0.073
maintenance of location GO:0051235 580 0.073
Worm
lipid localization GO:0010876 573 0.072
Worm
neuron development GO:0048666 199 0.072
cellular biosynthetic process GO:0044249 315 0.070
cellular localization GO:0051641 360 0.070
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.068
regulation of cell communication GO:0010646 176 0.068
carbohydrate derivative metabolic process GO:1901135 141 0.068
carbohydrate derivative catabolic process GO:1901136 82 0.068
catabolic process GO:0009056 318 0.067
defense response GO:0006952 296 0.067
translation GO:0006412 37 0.067
cellular macromolecular complex assembly GO:0034622 184 0.067
cell migration GO:0016477 306 0.067
lipid storage GO:0019915 565 0.065
Worm
inactivation of mapkkk activity GO:0051390 2 0.065
apoptotic cell clearance GO:0043277 111 0.065
purine ribonucleoside metabolic process GO:0046128 92 0.064
development of primary sexual characteristics GO:0045137 840 0.064
gonad development GO:0008406 840 0.061
purine ribonucleoside catabolic process GO:0046130 75 0.060
membrane organization GO:0061024 135 0.059
nucleotide catabolic process GO:0009166 77 0.058
muscle structure development GO:0061061 191 0.058
organelle fission GO:0048285 363 0.058
organic substance transport GO:0071702 113 0.057
receptor mediated endocytosis GO:0006898 715 0.057
post embryonic organ development GO:0048569 336 0.057
glycosyl compound metabolic process GO:1901657 100 0.057
actomyosin structure organization GO:0031032 154 0.057
muscle cell differentiation GO:0042692 171 0.056
growth GO:0040007 562 0.055
nucleotide metabolic process GO:0009117 108 0.054
nucleoside phosphate catabolic process GO:1901292 77 0.054
nucleic acid metabolic process GO:0090304 299 0.053
cell motility GO:0048870 313 0.053
engulfment of apoptotic cell GO:0043652 94 0.052
nucleobase containing compound catabolic process GO:0034655 114 0.052
macromolecular complex assembly GO:0065003 193 0.051
positive regulation of cellular process GO:0048522 332 0.051
organic substance biosynthetic process GO:1901576 323 0.051
muscle cell development GO:0055001 158 0.051
nuclear migration GO:0007097 54 0.050
regulation of cellular component organization GO:0051128 248 0.050
multi organism behavior GO:0051705 389 0.050
nucleoside catabolic process GO:0009164 78 0.050
organelle assembly GO:0070925 214 0.050
negative regulation of transporter activity GO:0032410 3 0.049
regulation of biological quality GO:0065008 741 0.049
Worm
glycosyl compound catabolic process GO:1901658 79 0.049
body morphogenesis GO:0010171 620 0.047
nucleoside phosphate metabolic process GO:0006753 108 0.047
membrane invagination GO:0010324 98 0.046
nucleoside metabolic process GO:0009116 99 0.046
actin cytoskeleton organization GO:0030036 184 0.046
purine nucleotide catabolic process GO:0006195 75 0.045
cellular protein metabolic process GO:0044267 279 0.045
regulation of cation channel activity GO:2001257 3 0.045
myofibril assembly GO:0030239 154 0.045
regulation of secretion GO:0051046 29 0.044
cytoskeleton organization GO:0007010 339 0.044
genitalia development GO:0048806 741 0.044
ribose phosphate metabolic process GO:0019693 99 0.044
regulation of cellular metabolic process GO:0031323 305 0.044
purine nucleoside triphosphate catabolic process GO:0009146 72 0.043
proteolysis GO:0006508 61 0.043
regulation of growth GO:0040008 409 0.042
female gamete generation GO:0007292 254 0.042
organonitrogen compound catabolic process GO:1901565 90 0.042
organelle fusion GO:0048284 8 0.041
purine ribonucleotide catabolic process GO:0009154 75 0.040
purine nucleoside metabolic process GO:0042278 92 0.040
cellular component assembly involved in morphogenesis GO:0010927 183 0.040
ribonucleoside triphosphate catabolic process GO:0009203 72 0.040
head development GO:0060322 1 0.039
positive regulation of developmental process GO:0051094 408 0.039
striated muscle myosin thick filament assembly GO:0071688 138 0.039
organophosphate metabolic process GO:0019637 125 0.038
purine nucleoside catabolic process GO:0006152 75 0.037
protein complex biogenesis GO:0070271 186 0.037
sex differentiation GO:0007548 909 0.037
protein complex assembly GO:0006461 186 0.037
negative regulation of ion transmembrane transport GO:0034766 3 0.036
negative regulation of cation channel activity GO:2001258 2 0.036
response to biotic stimulus GO:0009607 101 0.036
synaptic transmission GO:0007268 106 0.035
organ morphogenesis GO:0009887 67 0.035
phagocytosis GO:0006909 115 0.035
striated muscle cell development GO:0055002 157 0.035
gamete generation GO:0007276 461 0.035
regulation of signal transduction GO:0009966 135 0.034
regulation of defecation rhythm GO:2000746 3 0.034
lipid metabolic process GO:0006629 77 0.034
actin filament based process GO:0030029 191 0.034
positive regulation of growth GO:0045927 369 0.034
intracellular signal transduction GO:0035556 96 0.033
intracellular transport GO:0046907 77 0.033
regulation of phosphate metabolic process GO:0019220 81 0.033
single organism catabolic process GO:0044712 129 0.032
purine containing compound catabolic process GO:0072523 75 0.032
regulation of transport GO:0051049 91 0.032
positive regulation of developmental growth GO:0048639 354 0.032
regulation of developmental process GO:0050793 684 0.032
regeneration GO:0031099 4 0.032
regulation of metabolic process GO:0019222 478 0.032
cellular catabolic process GO:0044248 199 0.032
single organism intracellular transport GO:1902582 70 0.032
purine nucleotide metabolic process GO:0006163 95 0.031
phagocytosis engulfment GO:0006911 98 0.031
muscle tissue development GO:0060537 1 0.031
meiotic cell cycle GO:0051321 335 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.031
regulation of developmental growth GO:0048638 389 0.030
multicellular organism growth GO:0035264 385 0.029
reproductive structure development GO:0048608 850 0.029
negative regulation of transmembrane transport GO:0034763 3 0.029
germ cell development GO:0007281 351 0.029
calcium mediated signaling GO:0019722 3 0.029
regulation of reproductive process GO:2000241 66 0.029
positive regulation of response to stimulus GO:0048584 55 0.029
positive regulation of multicellular organismal process GO:0051240 417 0.029
protein catabolic process GO:0030163 162 0.029
negative regulation of cellular process GO:0048523 239 0.029
protein modification process GO:0036211 207 0.028
regulation of multicellular organismal development GO:2000026 317 0.028
cytokinesis GO:0000910 80 0.028
negative regulation of developmental process GO:0051093 227 0.028
autophagy GO:0006914 29 0.027
oogenesis GO:0048477 229 0.027
sensory organ morphogenesis GO:0090596 2 0.026
regulation of synapse assembly GO:0051963 2 0.026
neuron projection development GO:0031175 187 0.026
enzyme linked receptor protein signaling pathway GO:0007167 50 0.025
cellular response to chemical stimulus GO:0070887 129 0.025
regulation of lipid metabolic process GO:0019216 4 0.025
regulation of multi organism process GO:0043900 69 0.025
defecation rhythm GO:0035882 3 0.025
negative regulation of multicellular organismal process GO:0051241 236 0.025
response to other organism GO:0051707 101 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.025
pattern specification process GO:0007389 59 0.025
positive regulation of cell projection organization GO:0031346 4 0.025
myosin filament organization GO:0031033 138 0.024
ribonucleoside metabolic process GO:0009119 98 0.024
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.024
regulation of multicellular organism growth GO:0040014 373 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.023
regulation of exocytosis GO:0017157 1 0.023
neuron differentiation GO:0030182 217 0.023
oxoacid metabolic process GO:0043436 47 0.023
phosphate containing compound metabolic process GO:0006796 232 0.023
cellular nitrogen compound catabolic process GO:0044270 119 0.022
response to anesthetic GO:0072347 1 0.022
regulation of neuromuscular synaptic transmission GO:1900073 1 0.022
cell type specific apoptotic process GO:0097285 4 0.022
regulation of behavior GO:0050795 97 0.022
aromatic compound catabolic process GO:0019439 116 0.022
regulation of post embryonic development GO:0048580 260 0.021
myosin filament assembly GO:0031034 138 0.021
response to external biotic stimulus GO:0043207 101 0.021
inductive cell migration GO:0040039 145 0.021
cellular response to organic substance GO:0071310 119 0.020
cell cycle GO:0007049 526 0.020
regulation of cellular component size GO:0032535 40 0.020
cell cell signaling GO:0007267 118 0.020
regulation of gene expression epigenetic GO:0040029 163 0.020
meiotic nuclear division GO:0007126 300 0.020
regulation of synaptic transmission GO:0050804 34 0.020
establishment of protein localization to membrane GO:0090150 3 0.019
macromolecule catabolic process GO:0009057 202 0.019
macromolecule modification GO:0043412 218 0.019
nucleoside triphosphate metabolic process GO:0009141 87 0.019
ribonucleotide catabolic process GO:0009261 75 0.019
positive regulation of signaling GO:0023056 66 0.019
organophosphate catabolic process GO:0046434 81 0.019
axonal fasciculation GO:0007413 79 0.019
digestive tract development GO:0048565 122 0.019
purine containing compound metabolic process GO:0072521 95 0.018
cellular response to stress GO:0033554 162 0.018
response to organic substance GO:0010033 131 0.018
developmental growth GO:0048589 412 0.018
establishment of protein localization GO:0045184 50 0.018
tube development GO:0035295 126 0.018
asymmetric cell division GO:0008356 36 0.018
synaptic growth at neuromuscular junction GO:0051124 1 0.018
defense response to other organism GO:0098542 100 0.018
detection of external stimulus GO:0009581 4 0.018
negative regulation of post embryonic development GO:0048581 208 0.018
regulation of vulval development GO:0040028 248 0.017
cellular macromolecule biosynthetic process GO:0034645 247 0.017
regulation of cell size GO:0008361 30 0.017
neurogenesis GO:0022008 236 0.017
negative regulation of macromolecule metabolic process GO:0010605 229 0.017
ribonucleoside catabolic process GO:0042454 77 0.017
protein transport GO:0015031 45 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.017
organic cyclic compound catabolic process GO:1901361 119 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 5 0.016
purine nucleoside monophosphate metabolic process GO:0009126 43 0.016
positive regulation of multicellular organism growth GO:0040018 352 0.016
organic acid metabolic process GO:0006082 47 0.016
chemical homeostasis GO:0048878 29 0.016
regionalization GO:0003002 31 0.016
response to extracellular stimulus GO:0009991 38 0.016
nucleoside triphosphate catabolic process GO:0009143 72 0.016
regulation of cellular protein metabolic process GO:0032268 75 0.015
response to wounding GO:0009611 4 0.015
regulation of cell death GO:0010941 65 0.015
regulation of protein metabolic process GO:0051246 81 0.015
digestive tract morphogenesis GO:0048546 76 0.015
feeding behavior GO:0007631 70 0.015
cellular macromolecule localization GO:0070727 75 0.015
intercellular transport GO:0010496 1 0.015
cell morphogenesis involved in differentiation GO:0000904 112 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.014
purine nucleoside triphosphate metabolic process GO:0009144 87 0.014
single organism cellular localization GO:1902580 72 0.014
digestive system development GO:0055123 122 0.014
cell fate commitment GO:0045165 139 0.014
notch signaling pathway GO:0007219 22 0.014
neuron projection guidance GO:0097485 82 0.014
intracellular receptor signaling pathway GO:0030522 2 0.014
regulation of nematode larval development GO:0061062 260 0.014
response to unfolded protein GO:0006986 71 0.014
regulation of biosynthetic process GO:0009889 189 0.013
positive regulation of catabolic process GO:0009896 38 0.013
fertilization GO:0009566 63 0.013
generation of neurons GO:0048699 235 0.013
internal peptidyl lysine acetylation GO:0018393 3 0.013
cellular protein localization GO:0034613 75 0.013
regulation of intracellular signal transduction GO:1902531 77 0.013
vulval development GO:0040025 333 0.013
collagen and cuticulin based cuticle development GO:0040002 99 0.012
regulation of locomotion GO:0040012 161 0.012
spermatogenesis GO:0007283 41 0.012
response to abiotic stimulus GO:0009628 152 0.012
neurotransmitter secretion GO:0007269 26 0.012
neuromuscular junction development GO:0007528 2 0.012
chromatin remodeling GO:0006338 2 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
regulation of secretion by cell GO:1903530 21 0.012
response to nutrient levels GO:0031667 35 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
single organism behavior GO:0044708 83 0.012
negative regulation of gene expression GO:0010629 217 0.012
modification dependent protein catabolic process GO:0019941 32 0.012
dna conformation change GO:0071103 11 0.011
detection of abiotic stimulus GO:0009582 4 0.011
heterocycle catabolic process GO:0046700 119 0.011
positive regulation of cell communication GO:0010647 69 0.011
pharyngeal pumping GO:0043050 58 0.011
nucleoside monophosphate metabolic process GO:0009123 46 0.011
endosomal transport GO:0016197 26 0.011
rna interference GO:0016246 137 0.011
posttranscriptional gene silencing by rna GO:0035194 143 0.011
gene silencing by rna GO:0031047 143 0.011
regulation of cellular component biogenesis GO:0044087 26 0.011
cell proliferation GO:0008283 116 0.011
regulation of gene silencing GO:0060968 3 0.011
mesoderm development GO:0007498 27 0.011
rna biosynthetic process GO:0032774 169 0.011
oocyte differentiation GO:0009994 45 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
response to bacterium GO:0009617 86 0.010
neurological system process GO:0050877 53 0.010
cellular protein complex localization GO:0034629 3 0.010
regulation of protein import into nucleus GO:0042306 3 0.010
tissue morphogenesis GO:0048729 65 0.010
taxis GO:0042330 128 0.010
establishment of nucleus localization GO:0040023 55 0.010

acl-14 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
organ system cancer DOID:0050686 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
gastrointestinal system cancer DOID:3119 0 0.012