Caenorhabditis elegans

57 known processes

rbr-2 (CELE_ZK593.4)

Protein RBR-2

rbr-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.704
organ development GO:0048513 1102 0.476
body morphogenesis GO:0010171 620 0.382
gonad development GO:0008406 840 0.371
post embryonic development GO:0009791 2152 0.367
taxis GO:0042330 128 0.367
locomotion GO:0040011 1634 0.361
oogenesis GO:0048477 229 0.346
sexual reproduction GO:0019953 546 0.344
multicellular organism reproduction GO:0032504 819 0.313
neuron projection guidance GO:0097485 82 0.313
negative regulation of biological process GO:0048519 567 0.271
Zebrafish
multi organism reproductive process GO:0044703 867 0.263
regulation of metabolic process GO:0019222 478 0.258
Human Fly
positive regulation of multicellular organismal process GO:0051240 417 0.251
developmental process involved in reproduction GO:0003006 1165 0.228
regulation of multicellular organismal process GO:0051239 726 0.224
signaling GO:0023052 401 0.223
neurogenesis GO:0022008 236 0.219
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.211
cell development GO:0048468 696 0.193
sex differentiation GO:0007548 909 0.184
macromolecule catabolic process GO:0009057 202 0.178
multicellular organismal reproductive process GO:0048609 815 0.170
female gamete generation GO:0007292 254 0.153
cellular component assembly involved in morphogenesis GO:0010927 183 0.151
negative regulation of macromolecule metabolic process GO:0010605 229 0.146
gamete generation GO:0007276 461 0.141
axon development GO:0061564 163 0.138
embryo development ending in birth or egg hatching GO:0009792 2992 0.136
negative regulation of cellular process GO:0048523 239 0.133
Zebrafish
development of primary sexual characteristics GO:0045137 840 0.130
regulation of biological quality GO:0065008 741 0.129
single organism organelle organization GO:1902589 501 0.127
head development GO:0060322 1 0.125
neuron development GO:0048666 199 0.125
muscle cell differentiation GO:0042692 171 0.124
organelle assembly GO:0070925 214 0.121
regulation of nitrogen compound metabolic process GO:0051171 222 0.117
Human Fly
germ cell development GO:0007281 351 0.113
cell projection organization GO:0030030 231 0.113
negative regulation of response to stimulus GO:0048585 73 0.111
oviposition GO:0018991 364 0.111
regulation of signaling GO:0023051 172 0.110
organic substance catabolic process GO:1901575 294 0.110
signal transduction GO:0007165 317 0.110
regulation of cellular metabolic process GO:0031323 305 0.109
Human Fly
positive regulation of growth GO:0045927 369 0.108
reproductive structure development GO:0048608 850 0.108
cell cell signaling GO:0007267 118 0.108
neuron differentiation GO:0030182 217 0.107
growth GO:0040007 562 0.106
tube development GO:0035295 126 0.106
single organism signaling GO:0044700 401 0.106
regulation of cellular biosynthetic process GO:0031326 189 0.104
Human Fly
multicellular organismal reproductive behavior GO:0033057 384 0.101
establishment of localization GO:0051234 1171 0.101
regulation of developmental process GO:0050793 684 0.100
striated muscle cell development GO:0055002 157 0.099
regulation of gene expression epigenetic GO:0040029 163 0.097
developmental growth GO:0048589 412 0.095
macromolecule localization GO:0033036 771 0.093
striated muscle cell differentiation GO:0051146 158 0.092
cellular component movement GO:0006928 388 0.091
protein metabolic process GO:0019538 422 0.090
negative regulation of cellular metabolic process GO:0031324 95 0.089
muscle cell development GO:0055001 158 0.089
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.089
actomyosin structure organization GO:0031032 154 0.084
multi multicellular organism process GO:0044706 390 0.081
lipid storage GO:0019915 565 0.081
sensory organ morphogenesis GO:0090596 2 0.079
myofibril assembly GO:0030239 154 0.078
protein catabolic process GO:0030163 162 0.077
transport GO:0006810 1093 0.077
muscle structure development GO:0061061 191 0.077
multi organism reproductive behavior GO:0044705 387 0.076
single organism localization GO:1902578 518 0.076
regulation of developmental growth GO:0048638 389 0.075
positive regulation of developmental growth GO:0048639 354 0.075
organ morphogenesis GO:0009887 67 0.073
regulation of growth GO:0040008 409 0.072
lipid localization GO:0010876 573 0.071
multi organism behavior GO:0051705 389 0.070
cellular component morphogenesis GO:0032989 318 0.070
hermaphrodite genitalia development GO:0040035 734 0.069
generation of neurons GO:0048699 235 0.069
protein complex biogenesis GO:0070271 186 0.068
protein complex subunit organization GO:0071822 280 0.068
axonogenesis GO:0007409 102 0.067
cell migration GO:0016477 306 0.065
positive regulation of cellular process GO:0048522 332 0.065
Human Fly
maintenance of location GO:0051235 580 0.065
cell recognition GO:0008037 85 0.064
positive regulation of developmental process GO:0051094 408 0.064
anatomical structure formation involved in morphogenesis GO:0048646 250 0.064
cell morphogenesis involved in differentiation GO:0000904 112 0.062
protein complex assembly GO:0006461 186 0.061
regulation of response to stimulus GO:0048583 243 0.061
regulation of signal transduction GO:0009966 135 0.061
synaptic transmission GO:0007268 106 0.059
regulation of vulval development GO:0040028 248 0.059
cell projection morphogenesis GO:0048858 148 0.059
organelle localization GO:0051640 127 0.057
single organism reproductive process GO:0044702 1196 0.057
cellular protein metabolic process GO:0044267 279 0.057
chromatin assembly or disassembly GO:0006333 1 0.056
erbb signaling pathway GO:0038127 9 0.055
cell motility GO:0048870 313 0.055
regulation of cell communication GO:0010646 176 0.054
organelle organization GO:0006996 783 0.054
chemotaxis GO:0006935 120 0.053
canonical wnt signaling pathway GO:0060070 3 0.053
cell part morphogenesis GO:0032990 152 0.053
actin filament based process GO:0030029 191 0.052
behavior GO:0007610 527 0.051
Fly
localization of cell GO:0051674 313 0.051
neuron projection development GO:0031175 187 0.051
response to abiotic stimulus GO:0009628 152 0.050
regulation of macromolecule metabolic process GO:0060255 421 0.050
Human Fly
negative regulation of metabolic process GO:0009892 240 0.050
regulation of multicellular organismal development GO:2000026 317 0.049
catabolic process GO:0009056 318 0.049
negative regulation of neurogenesis GO:0050768 4 0.048
reproductive behavior GO:0019098 387 0.047
regulation of multicellular organism growth GO:0040014 373 0.047
vulval development GO:0040025 333 0.046
cytoskeleton organization GO:0007010 339 0.046
regulation of behavior GO:0050795 97 0.045
aging GO:0007568 812 0.045
neuron projection morphogenesis GO:0048812 114 0.045
embryonic morphogenesis GO:0048598 152 0.045
gene silencing GO:0016458 143 0.044
phagocytosis GO:0006909 115 0.044
negative regulation of multicellular organismal process GO:0051241 236 0.044
striated muscle myosin thick filament assembly GO:0071688 138 0.043
response to chemical GO:0042221 356 0.043
multicellular organism growth GO:0035264 385 0.043
response to external stimulus GO:0009605 289 0.041
nucleobase containing compound metabolic process GO:0006139 406 0.041
Human Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.041
Human Fly
positive regulation of multicellular organism growth GO:0040018 352 0.041
death GO:0016265 547 0.041
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 165 0.041
Human Fly
cellular protein complex assembly GO:0043623 178 0.040
myosin filament assembly GO:0031034 138 0.039
negative regulation of biosynthetic process GO:0009890 65 0.039
regulation of localization GO:0032879 194 0.038
regulation of gene expression GO:0010468 366 0.037
Human Fly
transcription dna templated GO:0006351 168 0.037
Human Fly
neuron recognition GO:0008038 83 0.037
single organism transport GO:0044765 447 0.037
cellular component assembly GO:0022607 293 0.037
macromolecular complex subunit organization GO:0043933 320 0.037
cell surface receptor signaling pathway GO:0007166 149 0.036
protein localization GO:0008104 205 0.036
nervous system development GO:0007399 253 0.036
synaptic vesicle transport GO:0048489 21 0.035
regulation of biosynthetic process GO:0009889 189 0.035
Human Fly
regulation of reproductive process GO:2000241 66 0.034
mitotic nuclear division GO:0007067 89 0.034
actin cytoskeleton organization GO:0030036 184 0.034
cell division GO:0051301 262 0.034
axon guidance GO:0007411 82 0.033
chromatin organization GO:0006325 32 0.033
cell death GO:0008219 547 0.033
Zebrafish
rna metabolic process GO:0016070 228 0.033
Human Fly
negative regulation of signaling GO:0023057 61 0.032
regulation of multi organism process GO:0043900 69 0.032
regulation of post embryonic development GO:0048580 260 0.032
nucleobase containing compound biosynthetic process GO:0034654 184 0.032
Human Fly
programmed cell death GO:0012501 500 0.032
Zebrafish
intracellular signal transduction GO:0035556 96 0.032
establishment of organelle localization GO:0051656 123 0.031
regulation of pharyngeal pumping GO:0043051 36 0.031
cellular protein modification process GO:0006464 207 0.031
cellular component biogenesis GO:0044085 297 0.031
regulation of primary metabolic process GO:0080090 292 0.030
Human Fly
negative regulation of developmental process GO:0051093 227 0.030
aromatic compound biosynthetic process GO:0019438 192 0.029
Human Fly
myosin filament organization GO:0031033 138 0.029
regulation of cellular component organization GO:0051128 248 0.029
dosage compensation by hypoactivation of x chromosome GO:0042464 11 0.029
multicellular organismal aging GO:0010259 812 0.029
gene silencing by rna GO:0031047 143 0.028
negative regulation of rna biosynthetic process GO:1902679 53 0.028
genitalia development GO:0048806 741 0.028
oxoacid metabolic process GO:0043436 47 0.028
internal peptidyl lysine acetylation GO:0018393 3 0.027
Fly
endocytosis GO:0006897 819 0.026
proximal distal pattern formation GO:0009954 6 0.026
negative regulation of signal transduction GO:0009968 60 0.026
apoptotic process GO:0006915 478 0.026
Zebrafish
negative regulation of cell communication GO:0010648 61 0.026
negative regulation of gene expression GO:0010629 217 0.026
nuclear migration GO:0007097 54 0.025
negative regulation of nucleic acid templated transcription GO:1903507 53 0.024
cell cycle GO:0007049 526 0.024
system process GO:0003008 136 0.024
cellular catabolic process GO:0044248 199 0.023
microtubule polymerization or depolymerization GO:0031109 22 0.023
cellular macromolecule catabolic process GO:0044265 73 0.023
tissue morphogenesis GO:0048729 65 0.023
intracellular receptor signaling pathway GO:0030522 2 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.022
Human Fly
skeletal muscle organ development GO:0060538 3 0.022
axonal fasciculation GO:0007413 79 0.022
positive regulation of gene expression GO:0010628 112 0.022
Human Fly
meiotic cell cycle GO:0051321 335 0.022
organic cyclic compound biosynthetic process GO:1901362 195 0.022
Human Fly
macromolecule modification GO:0043412 218 0.022
positive regulation of neurogenesis GO:0050769 4 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.022
cellular ketone metabolic process GO:0042180 14 0.022
organic cyclic compound catabolic process GO:1901361 119 0.022
posttranscriptional gene silencing GO:0016441 143 0.021
mitotic cell cycle process GO:1903047 194 0.021
pronuclear migration GO:0035046 51 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.021
Human Fly
production of sirna involved in rna interference GO:0030422 6 0.021
negative regulation of rna metabolic process GO:0051253 53 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
dendrite development GO:0016358 42 0.021
pharyngeal pumping GO:0043050 58 0.021
regulation of cellular protein metabolic process GO:0032268 75 0.020
macromolecular complex assembly GO:0065003 193 0.020
organic substance transport GO:0071702 113 0.020
cytoskeleton dependent cytokinesis GO:0061640 35 0.020
regulation of catabolic process GO:0009894 57 0.020
nuclear pore distribution GO:0031081 2 0.020
organelle fission GO:0048285 363 0.019
regulation of organelle organization GO:0033043 164 0.019
response to biotic stimulus GO:0009607 101 0.019
dna conformation change GO:0071103 11 0.019
epidermal growth factor receptor signaling pathway GO:0007173 9 0.019
regulation of locomotion GO:0040012 161 0.018
establishment of localization in cell GO:0051649 318 0.018
cellular amino acid metabolic process GO:0006520 15 0.018
cell proliferation GO:0008283 116 0.018
posttranscriptional regulation of gene expression GO:0010608 166 0.018
amine metabolic process GO:0009308 15 0.018
regulation of rna biosynthetic process GO:2001141 165 0.018
Human Fly
dauer larval development GO:0040024 92 0.018
protein phosphorylation GO:0006468 85 0.018
regulation of cellular catabolic process GO:0031329 51 0.018
response to temperature stimulus GO:0009266 66 0.018
fertilization GO:0009566 63 0.018
regulation of canonical wnt signaling pathway GO:0060828 1 0.017
cellular biosynthetic process GO:0044249 315 0.017
Human Fly
receptor mediated endocytosis GO:0006898 715 0.017
digestive tract morphogenesis GO:0048546 76 0.017
digestive system development GO:0055123 122 0.017
vesicle mediated transport GO:0016192 852 0.017
regulation of rna metabolic process GO:0051252 173 0.017
Human Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
dna packaging GO:0006323 7 0.017
reproductive system development GO:0061458 850 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.016
Human Fly
posttranscriptional gene silencing by rna GO:0035194 143 0.016
response to wounding GO:0009611 4 0.016
negative regulation of cellular biosynthetic process GO:0031327 65 0.016
organic acid metabolic process GO:0006082 47 0.016
cellular macromolecular complex assembly GO:0034622 184 0.016
regulation of cell proliferation GO:0042127 105 0.016
secretion by cell GO:0032940 138 0.015
determination of adult lifespan GO:0008340 812 0.015
apoptotic cell clearance GO:0043277 111 0.015
eating behavior GO:0042755 59 0.015
nucleoside phosphate metabolic process GO:0006753 108 0.015
membrane organization GO:0061024 135 0.014
microtubule based process GO:0007017 182 0.014
regulation of cell differentiation GO:0045595 81 0.014
epithelial tube morphogenesis GO:0060562 1 0.014
feeding behavior GO:0007631 70 0.014
carboxylic acid metabolic process GO:0019752 34 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.014
gene expression GO:0010467 412 0.014
Human Fly
regulation of oviposition GO:0046662 43 0.014
cellular protein localization GO:0034613 75 0.014
muscle tissue development GO:0060537 1 0.014
synaptic vesicle localization GO:0097479 22 0.014
chromatin assembly GO:0031497 1 0.014
ras protein signal transduction GO:0007265 31 0.014
internal protein amino acid acetylation GO:0006475 3 0.014
Fly
post embryonic organ development GO:0048569 336 0.014
regulation of organ morphogenesis GO:2000027 4 0.014
chromosome segregation GO:0007059 180 0.014
nucleic acid templated transcription GO:0097659 169 0.013
Human Fly
rna interference GO:0016246 137 0.013
neurological system process GO:0050877 53 0.013
negative regulation of cellular component organization GO:0051129 33 0.013
establishment of protein localization to membrane GO:0090150 3 0.013
phagocytosis engulfment GO:0006911 98 0.013
regulation of feeding behavior GO:0060259 38 0.013
negative regulation of transcription dna templated GO:0045892 53 0.012
positive regulation of chromosome organization GO:2001252 2 0.012
detection of external stimulus GO:0009581 4 0.012
dsrna fragmentation GO:0031050 10 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
cellular localization GO:0051641 360 0.012
peptidyl lysine acetylation GO:0018394 3 0.012
Fly
phosphorus metabolic process GO:0006793 232 0.012
negative regulation of gene expression epigenetic GO:0045814 2 0.012
proteasomal protein catabolic process GO:0010498 20 0.012
developmental growth involved in morphogenesis GO:0060560 37 0.012
histone h3 acetylation GO:0043966 1 0.011
Fly
cell morphogenesis GO:0000902 163 0.011
regulation of nucleocytoplasmic transport GO:0046822 3 0.011
establishment of synaptic vesicle localization GO:0097480 21 0.011
macromolecule biosynthetic process GO:0009059 250 0.011
Human Fly
negative regulation of neuron differentiation GO:0045665 4 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.011
digestive tract development GO:0048565 122 0.011
carbohydrate biosynthetic process GO:0016051 4 0.011
regulation of wnt signaling pathway GO:0030111 9 0.011
negative regulation of ion transmembrane transport GO:0034766 3 0.011
detection of abiotic stimulus GO:0009582 4 0.011
regulation of protein metabolic process GO:0051246 81 0.011
establishment of vesicle localization GO:0051650 23 0.011
engulfment of apoptotic cell GO:0043652 94 0.010
pigmentation GO:0043473 2 0.010
nucleic acid metabolic process GO:0090304 299 0.010
Human Fly
response to other organism GO:0051707 101 0.010
translational initiation GO:0006413 2 0.010
wnt signaling pathway GO:0016055 27 0.010
organonitrogen compound metabolic process GO:1901564 151 0.010
cell fate commitment GO:0045165 139 0.010

rbr-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
reproductive organ cancer DOID:193 0 0.027
female reproductive organ cancer DOID:120 0 0.027
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.027
disease of anatomical entity DOID:7 0 0.012