Caenorhabditis elegans

29 known processes

apm-3 (CELE_F53H8.1)

Protein APM-3

apm-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.713
post embryonic development GO:0009791 2152 0.408
organelle fission GO:0048285 363 0.396
multicellular organismal reproductive process GO:0048609 815 0.371
sex differentiation GO:0007548 909 0.356
locomotion GO:0040011 1634 0.353
neuron projection guidance GO:0097485 82 0.319
regulation of biosynthetic process GO:0009889 189 0.290
organ development GO:0048513 1102 0.276
mesodermal cell migration GO:0008078 9 0.274
neuron differentiation GO:0030182 217 0.268
cellular macromolecule biosynthetic process GO:0034645 247 0.257
embryo development ending in birth or egg hatching GO:0009792 2992 0.255
regulation of macromolecule biosynthetic process GO:0010556 189 0.235
regulation of transcription dna templated GO:0006355 164 0.231
macromolecule biosynthetic process GO:0009059 250 0.222
signaling GO:0023052 401 0.211
Mouse
development of primary sexual characteristics GO:0045137 840 0.205
negative regulation of biological process GO:0048519 567 0.205
establishment of localization GO:0051234 1171 0.199
Mouse
single organism transport GO:0044765 447 0.191
Mouse
organic cyclic compound biosynthetic process GO:1901362 195 0.190
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.190
axon development GO:0061564 163 0.188
cellular biosynthetic process GO:0044249 315 0.181
transport GO:0006810 1093 0.177
Mouse
biosynthetic process GO:0009058 323 0.174
reproductive structure development GO:0048608 850 0.173
meiotic cell cycle GO:0051321 335 0.169
cell development GO:0048468 696 0.167
death GO:0016265 547 0.167
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.163
growth GO:0040007 562 0.162
cell migration GO:0016477 306 0.160
regulation of primary metabolic process GO:0080090 292 0.155
taxis GO:0042330 128 0.149
organic substance biosynthetic process GO:1901576 323 0.147
rna metabolic process GO:0016070 228 0.146
hermaphrodite genitalia development GO:0040035 734 0.144
cell projection organization GO:0030030 231 0.142
multicellular organism reproduction GO:0032504 819 0.142
single organism localization GO:1902578 518 0.135
Mouse
neuron development GO:0048666 199 0.135
cell morphogenesis involved in differentiation GO:0000904 112 0.134
body morphogenesis GO:0010171 620 0.133
single organism reproductive process GO:0044702 1196 0.132
meiotic nuclear division GO:0007126 300 0.130
regulation of nitrogen compound metabolic process GO:0051171 222 0.130
regulation of cell cycle GO:0051726 194 0.128
developmental process involved in reproduction GO:0003006 1165 0.126
regulation of multicellular organismal development GO:2000026 317 0.125
signal transduction GO:0007165 317 0.124
single organism signaling GO:0044700 401 0.121
Mouse
transcription dna templated GO:0006351 168 0.118
protein metabolic process GO:0019538 422 0.117
mitotic cell cycle process GO:1903047 194 0.116
gonad development GO:0008406 840 0.115
regulation of nucleic acid templated transcription GO:1903506 165 0.115
cellular protein metabolic process GO:0044267 279 0.114
rna biosynthetic process GO:0032774 169 0.114
endocytosis GO:0006897 819 0.113
cell motility GO:0048870 313 0.113
generation of neurons GO:0048699 235 0.112
cellular component movement GO:0006928 388 0.111
Mouse
regulation of growth GO:0040008 409 0.111
nucleic acid templated transcription GO:0097659 169 0.111
aromatic compound biosynthetic process GO:0019438 192 0.111
positive regulation of multicellular organismal process GO:0051240 417 0.109
gene expression GO:0010467 412 0.108
negative regulation of cellular process GO:0048523 239 0.107
regulation of multicellular organismal process GO:0051239 726 0.107
nucleobase containing compound metabolic process GO:0006139 406 0.105
cell cycle GO:0007049 526 0.105
response to external stimulus GO:0009605 289 0.104
developmental growth GO:0048589 412 0.102
apoptotic process GO:0006915 478 0.101
neuron projection development GO:0031175 187 0.100
cell cell signaling GO:0007267 118 0.099
Mouse
multicellular organismal aging GO:0010259 812 0.099
cell cycle process GO:0022402 482 0.098
post embryonic organ development GO:0048569 336 0.097
aging GO:0007568 812 0.097
regulation of cell communication GO:0010646 176 0.097
cellular protein modification process GO:0006464 207 0.096
regulation of biological quality GO:0065008 741 0.095
nervous system development GO:0007399 253 0.094
regulation of nematode larval development GO:0061062 260 0.094
protein modification process GO:0036211 207 0.092
nucleobase containing compound biosynthetic process GO:0034654 184 0.092
heterocycle biosynthetic process GO:0018130 187 0.092
epithelium development GO:0060429 68 0.089
multi organism reproductive process GO:0044703 867 0.088
vesicle mediated transport GO:0016192 852 0.088
Mouse
receptor mediated endocytosis GO:0006898 715 0.087
axon guidance GO:0007411 82 0.085
reproductive system development GO:0061458 850 0.085
mitotic nuclear division GO:0007067 89 0.084
response to chemical GO:0042221 356 0.083
neurogenesis GO:0022008 236 0.082
regulation of developmental growth GO:0048638 389 0.080
regulation of response to stimulus GO:0048583 243 0.078
regulation of signaling GO:0023051 172 0.078
organ morphogenesis GO:0009887 67 0.078
positive regulation of cellular process GO:0048522 332 0.078
chemotaxis GO:0006935 120 0.075
positive regulation of growth GO:0045927 369 0.075
regulation of macromolecule metabolic process GO:0060255 421 0.075
multicellular organism growth GO:0035264 385 0.074
programmed cell death GO:0012501 500 0.073
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.073
neuron projection morphogenesis GO:0048812 114 0.072
regulation of cell cycle process GO:0010564 145 0.072
positive regulation of developmental growth GO:0048639 354 0.071
negative regulation of multicellular organismal process GO:0051241 236 0.070
regulation of multicellular organism growth GO:0040014 373 0.070
regulation of localization GO:0032879 194 0.070
regulation of metabolic process GO:0019222 478 0.069
genitalia development GO:0048806 741 0.069
negative regulation of developmental process GO:0051093 227 0.068
macromolecule localization GO:0033036 771 0.068
muscle structure development GO:0061061 191 0.067
regulation of post embryonic development GO:0048580 260 0.067
cell death GO:0008219 547 0.067
regulation of cellular metabolic process GO:0031323 305 0.066
regulation of cellular biosynthetic process GO:0031326 189 0.066
head development GO:0060322 1 0.065
epithelial tube morphogenesis GO:0060562 1 0.065
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.064
lipid storage GO:0019915 565 0.064
axonogenesis GO:0007409 102 0.064
oogenesis GO:0048477 229 0.064
macromolecule modification GO:0043412 218 0.064
organelle organization GO:0006996 783 0.063
determination of adult lifespan GO:0008340 812 0.063
regulation of rna biosynthetic process GO:2001141 165 0.063
establishment of localization in cell GO:0051649 318 0.062
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.061
regulation of developmental process GO:0050793 684 0.060
nucleic acid metabolic process GO:0090304 299 0.060
negative regulation of macromolecule metabolic process GO:0010605 229 0.059
negative regulation of cellular biosynthetic process GO:0031327 65 0.058
cellular component morphogenesis GO:0032989 318 0.056
lipid localization GO:0010876 573 0.056
cell part morphogenesis GO:0032990 152 0.055
behavior GO:0007610 527 0.055
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.055
cytoskeleton organization GO:0007010 339 0.054
maintenance of location GO:0051235 580 0.054
positive regulation of cellular metabolic process GO:0031325 178 0.053
canonical wnt signaling pathway GO:0060070 3 0.053
oviposition GO:0018991 364 0.052
cell proliferation GO:0008283 116 0.051
localization of cell GO:0051674 313 0.050
positive regulation of developmental process GO:0051094 408 0.050
striated muscle cell development GO:0055002 157 0.049
regulation of signal transduction GO:0009966 135 0.048
negative regulation of metabolic process GO:0009892 240 0.047
inductive cell migration GO:0040039 145 0.045
synaptic transmission GO:0007268 106 0.045
Mouse
catabolic process GO:0009056 318 0.042
cell morphogenesis GO:0000902 163 0.042
cellular protein complex assembly GO:0043623 178 0.042
single organism organelle organization GO:1902589 501 0.042
regulation of vulval development GO:0040028 248 0.041
cell division GO:0051301 262 0.041
multi organism behavior GO:0051705 389 0.041
cellular component biogenesis GO:0044085 297 0.041
transcription from rna polymerase ii promoter GO:0006366 149 0.041
gamete generation GO:0007276 461 0.040
positive regulation of gene expression GO:0010628 112 0.040
regulation of gene expression GO:0010468 366 0.039
cellular component assembly GO:0022607 293 0.039
positive regulation of macromolecule metabolic process GO:0010604 149 0.039
sexual reproduction GO:0019953 546 0.039
rho protein signal transduction GO:0007266 2 0.039
phagocytosis GO:0006909 115 0.038
regulation of neurogenesis GO:0050767 40 0.037
regulation of reproductive process GO:2000241 66 0.037
cellular macromolecular complex assembly GO:0034622 184 0.037
regulation of cellular component organization GO:0051128 248 0.036
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.036
positive regulation of metabolic process GO:0009893 187 0.036
response to organic substance GO:0010033 131 0.035
positive regulation of multicellular organism growth GO:0040018 352 0.035
multicellular organismal reproductive behavior GO:0033057 384 0.035
small molecule metabolic process GO:0044281 186 0.035
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.035
negative regulation of vulval development GO:0040027 206 0.034
positive regulation of signaling GO:0023056 66 0.034
establishment of organelle localization GO:0051656 123 0.033
Mouse
regulation of canonical wnt signaling pathway GO:0060828 1 0.033
cell type specific apoptotic process GO:0097285 4 0.033
regulation of cellular protein metabolic process GO:0032268 75 0.032
phagocytosis engulfment GO:0006911 98 0.032
reproductive behavior GO:0019098 387 0.032
secretion GO:0046903 147 0.031
vulval development GO:0040025 333 0.031
striated muscle cell differentiation GO:0051146 158 0.031
positive regulation of cell communication GO:0010647 69 0.030
cellular nitrogen compound biosynthetic process GO:0044271 192 0.030
regulation of cell proliferation GO:0042127 105 0.030
regulation of molecular function GO:0065009 89 0.030
tube development GO:0035295 126 0.030
response to wounding GO:0009611 4 0.029
negative regulation of cellular metabolic process GO:0031324 95 0.029
multi multicellular organism process GO:0044706 390 0.029
regulation of transport GO:0051049 91 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.028
actomyosin structure organization GO:0031032 154 0.028
response to topologically incorrect protein GO:0035966 82 0.028
female gamete generation GO:0007292 254 0.028
regulation of nucleocytoplasmic transport GO:0046822 3 0.028
phosphorus metabolic process GO:0006793 232 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.027
protein complex subunit organization GO:0071822 280 0.027
cellular localization GO:0051641 360 0.027
Mouse
negative regulation of nematode larval development GO:0061064 208 0.027
regulation of mitotic cell cycle GO:0007346 76 0.027
meiotic chromosome segregation GO:0045132 139 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 12 0.027
positive regulation of cell projection organization GO:0031346 4 0.027
meiotic cell cycle process GO:1903046 170 0.026
regulation of rna metabolic process GO:0051252 173 0.026
multi organism reproductive behavior GO:0044705 387 0.026
negative regulation of gene expression GO:0010629 217 0.026
positive regulation of biosynthetic process GO:0009891 109 0.026
regulation of cellular ketone metabolic process GO:0010565 3 0.026
regulation of neuron differentiation GO:0045664 40 0.025
negative regulation of biosynthetic process GO:0009890 65 0.025
membrane invagination GO:0010324 98 0.025
macromolecular complex assembly GO:0065003 193 0.025
muscle cell development GO:0055001 158 0.025
protein localization GO:0008104 205 0.025
organic substance catabolic process GO:1901575 294 0.025
negative regulation of rna biosynthetic process GO:1902679 53 0.025
positive regulation of rna metabolic process GO:0051254 103 0.025
regulation of nuclear division GO:0051783 115 0.024
chromosome segregation GO:0007059 180 0.024
oxoacid metabolic process GO:0043436 47 0.024
response to abiotic stimulus GO:0009628 152 0.024
positive regulation of cell cycle GO:0045787 55 0.024
regulation of cell division GO:0051302 142 0.023
cellular response to organic substance GO:0071310 119 0.023
cell surface receptor signaling pathway GO:0007166 149 0.023
macromolecule catabolic process GO:0009057 202 0.023
intracellular transport GO:0046907 77 0.022
Mouse
single organism carbohydrate metabolic process GO:0044723 29 0.022
homeostatic process GO:0042592 51 0.022
regulation of intracellular signal transduction GO:1902531 77 0.022
regulation of protein metabolic process GO:0051246 81 0.022
organic substance transport GO:0071702 113 0.022
actin cytoskeleton organization GO:0030036 184 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 16 0.022
apoptotic cell clearance GO:0043277 111 0.022
regulation of phosphate metabolic process GO:0019220 81 0.022
neuron recognition GO:0008038 83 0.021
lamellipodium assembly GO:0030032 2 0.021
enzyme linked receptor protein signaling pathway GO:0007167 50 0.021
regulation of cellular component movement GO:0051270 62 0.021
regulation of cellular component size GO:0032535 40 0.021
negative regulation of response to stimulus GO:0048585 73 0.021
single organism intracellular transport GO:1902582 70 0.020
Mouse
secretion by cell GO:0032940 138 0.020
negative regulation of cell communication GO:0010648 61 0.020
negative regulation of post embryonic development GO:0048581 208 0.020
pattern specification process GO:0007389 59 0.020
organic acid metabolic process GO:0006082 47 0.020
organelle assembly GO:0070925 214 0.019
muscle organ morphogenesis GO:0048644 4 0.019
regulation of endocytosis GO:0030100 25 0.019
positive regulation of neuron projection development GO:0010976 4 0.019
regulation of ras protein signal transduction GO:0046578 41 0.019
carboxylic acid metabolic process GO:0019752 34 0.019
myofibril assembly GO:0030239 154 0.019
cellular response to stress GO:0033554 162 0.019
regulation of cell differentiation GO:0045595 81 0.019
protein complex biogenesis GO:0070271 186 0.019
regulation of phosphorus metabolic process GO:0051174 81 0.019
peptidyl tyrosine phosphorylation GO:0018108 2 0.018
actin cytoskeleton reorganization GO:0031532 4 0.018
response to biotic stimulus GO:0009607 101 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
regulation of behavior GO:0050795 97 0.017
negative regulation of rna metabolic process GO:0051253 53 0.017
ras protein signal transduction GO:0007265 31 0.017
regulation of locomotion GO:0040012 161 0.017
glycoprotein metabolic process GO:0009100 29 0.017
sensory organ morphogenesis GO:0090596 2 0.017
germ cell development GO:0007281 351 0.017
positive regulation of protein transport GO:0051222 4 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
response to endoplasmic reticulum stress GO:0034976 71 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
glycosylation GO:0070085 20 0.017
positive regulation of rna biosynthetic process GO:1902680 102 0.016
tissue morphogenesis GO:0048729 65 0.016
positive regulation of post embryonic development GO:0048582 54 0.016
mechanosensory behavior GO:0007638 25 0.016
dorsal ventral axon guidance GO:0033563 19 0.016
cellular amine metabolic process GO:0044106 15 0.015
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.015
cell projection morphogenesis GO:0048858 148 0.015
protein catabolic process GO:0030163 162 0.015
proteolysis GO:0006508 61 0.015
membrane organization GO:0061024 135 0.015
positive regulation of phosphorus metabolic process GO:0010562 56 0.014
regulation of meiotic cell cycle GO:0051445 136 0.014
regulation of wnt signaling pathway GO:0030111 9 0.014
dendrite development GO:0016358 42 0.014
muscle cell differentiation GO:0042692 171 0.014
amine metabolic process GO:0009308 15 0.014
response to temperature stimulus GO:0009266 66 0.014
macromolecular complex subunit organization GO:0043933 320 0.014
single organism cellular localization GO:1902580 72 0.014
myosin filament assembly GO:0031034 138 0.014
negative regulation of cell cycle GO:0045786 53 0.014
regulation of neurotransmitter levels GO:0001505 36 0.014
single organism behavior GO:0044708 83 0.014
organonitrogen compound catabolic process GO:1901565 90 0.014
cellular ketone metabolic process GO:0042180 14 0.013
negative regulation of neurogenesis GO:0050768 4 0.013
actin filament based process GO:0030029 191 0.013
immune response GO:0006955 192 0.013
cellular protein localization GO:0034613 75 0.013
negative regulation of signaling GO:0023057 61 0.013
regulation of organelle organization GO:0033043 164 0.013
tissue development GO:0009888 112 0.013
engulfment of apoptotic cell GO:0043652 94 0.013
positive regulation of cellular biosynthetic process GO:0031328 109 0.013
small gtpase mediated signal transduction GO:0007264 32 0.013
cellular response to unfolded protein GO:0034620 71 0.013
carbohydrate metabolic process GO:0005975 34 0.013
regulation of vesicle mediated transport GO:0060627 27 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
peptidyl amino acid modification GO:0018193 58 0.013
cell recognition GO:0008037 85 0.012
lamellipodium organization GO:0097581 2 0.012
protein modification by small protein conjugation or removal GO:0070647 40 0.012
negative regulation of neuron differentiation GO:0045665 4 0.012
myosin filament organization GO:0031033 138 0.012
response to bacterium GO:0009617 86 0.012
positive regulation of nucleic acid templated transcription GO:1903508 102 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.012
response to external biotic stimulus GO:0043207 101 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
regulation of protein targeting GO:1903533 3 0.012
cellular response to endogenous stimulus GO:0071495 32 0.012
cellular homeostasis GO:0019725 22 0.012
axonal fasciculation GO:0007413 79 0.012
cellular macromolecule catabolic process GO:0044265 73 0.012
phosphate containing compound metabolic process GO:0006796 232 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
skeletal muscle organ development GO:0060538 3 0.012
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.012
wnt signaling pathway GO:0016055 27 0.012
regulation of epithelial cell proliferation GO:0050678 1 0.011
regulation of cell death GO:0010941 65 0.011
positive regulation of transport GO:0051050 32 0.011
positive regulation of molecular function GO:0044093 61 0.011
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
regulation of protein stability GO:0031647 3 0.011
response to other organism GO:0051707 101 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
negative regulation of response to external stimulus GO:0032102 3 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.010
microtubule based process GO:0007017 182 0.010
Mouse
protein transport GO:0015031 45 0.010
negative regulation of signal transduction GO:0009968 60 0.010
regulation of protein import into nucleus GO:0042306 3 0.010
positive regulation of neuron differentiation GO:0045666 4 0.010
regulation of cellular ph GO:0030641 4 0.010
defense response GO:0006952 296 0.010
response to heat GO:0009408 50 0.010
organonitrogen compound metabolic process GO:1901564 151 0.010
regulation of protein modification process GO:0031399 46 0.010
regulation of anatomical structure morphogenesis GO:0022603 51 0.010
regulation of cell motility GO:2000145 57 0.010
cell fate commitment GO:0045165 139 0.010

apm-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
nervous system disease DOID:863 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012