Caenorhabditis elegans

47 known processes

efn-4 (CELE_F56A11.3)

Protein EFN-4

efn-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.360
head development GO:0060322 1 0.332
Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.286
reproductive structure development GO:0048608 850 0.220
developmental process involved in reproduction GO:0003006 1165 0.218
sex differentiation GO:0007548 909 0.188
organ development GO:0048513 1102 0.183
Worm Fly
regulation of macromolecule metabolic process GO:0060255 421 0.182
multicellular organism reproduction GO:0032504 819 0.182
Worm
vesicle mediated transport GO:0016192 852 0.175
cell development GO:0048468 696 0.172
Fly
establishment of localization GO:0051234 1171 0.170
reproductive system development GO:0061458 850 0.167
regulation of developmental process GO:0050793 684 0.166
transport GO:0006810 1093 0.163
neuron projection development GO:0031175 187 0.162
Fly
heterocycle biosynthetic process GO:0018130 187 0.159
regulation of rna metabolic process GO:0051252 173 0.140
multicellular organismal reproductive process GO:0048609 815 0.140
Worm
neuron differentiation GO:0030182 217 0.137
Fly
gonad development GO:0008406 840 0.132
transcription dna templated GO:0006351 168 0.127
locomotion GO:0040011 1634 0.123
single organism organelle organization GO:1902589 501 0.121
multi organism reproductive process GO:0044703 867 0.118
Worm
development of primary sexual characteristics GO:0045137 840 0.114
hermaphrodite genitalia development GO:0040035 734 0.114
gene expression GO:0010467 412 0.113
regulation of multicellular organismal process GO:0051239 726 0.108
Worm
single organism signaling GO:0044700 401 0.108
Worm
macromolecule localization GO:0033036 771 0.108
genitalia development GO:0048806 741 0.107
post embryonic development GO:0009791 2152 0.105
neurogenesis GO:0022008 236 0.103
Fly
gamete generation GO:0007276 461 0.099
Worm
regulation of transcription dna templated GO:0006355 164 0.098
generation of neurons GO:0048699 235 0.097
Fly
receptor mediated endocytosis GO:0006898 715 0.097
protein metabolic process GO:0019538 422 0.097
cell fate commitment GO:0045165 139 0.096
regulation of biological quality GO:0065008 741 0.096
axon development GO:0061564 163 0.093
Fly
sexual reproduction GO:0019953 546 0.093
Worm
cellular biosynthetic process GO:0044249 315 0.093
signal transduction GO:0007165 317 0.092
Worm
negative regulation of biological process GO:0048519 567 0.089
Worm
gastrulation GO:0007369 58 0.088
body morphogenesis GO:0010171 620 0.087
organelle organization GO:0006996 783 0.087
aromatic compound biosynthetic process GO:0019438 192 0.086
post embryonic organ development GO:0048569 336 0.084
single organism reproductive process GO:0044702 1196 0.083
Worm
regulation of response to stimulus GO:0048583 243 0.082
positive regulation of multicellular organismal process GO:0051240 417 0.082
taxis GO:0042330 128 0.078
Fly
nucleobase containing compound metabolic process GO:0006139 406 0.077
regulation of multicellular organismal development GO:2000026 317 0.076
regulation of vulval development GO:0040028 248 0.075
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.075
nucleic acid metabolic process GO:0090304 299 0.071
germ cell development GO:0007281 351 0.071
organic substance biosynthetic process GO:1901576 323 0.070
nucleic acid templated transcription GO:0097659 169 0.069
cellular nitrogen compound biosynthetic process GO:0044271 192 0.068
positive regulation of cellular process GO:0048522 332 0.067
oviposition GO:0018991 364 0.067
cell death GO:0008219 547 0.067
multicellular organismal reproductive behavior GO:0033057 384 0.067
behavior GO:0007610 527 0.067
regulation of cell communication GO:0010646 176 0.067
neuron development GO:0048666 199 0.066
Fly
rna biosynthetic process GO:0032774 169 0.066
growth GO:0040007 562 0.066
maintenance of location GO:0051235 580 0.065
regulation of nitrogen compound metabolic process GO:0051171 222 0.065
regulation of rna biosynthetic process GO:2001141 165 0.063
negative regulation of metabolic process GO:0009892 240 0.063
lipid localization GO:0010876 573 0.062
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.062
multi organism reproductive behavior GO:0044705 387 0.061
lipid storage GO:0019915 565 0.061
organic cyclic compound biosynthetic process GO:1901362 195 0.060
positive regulation of metabolic process GO:0009893 187 0.059
single organism localization GO:1902578 518 0.059
vulval development GO:0040025 333 0.058
single organism transport GO:0044765 447 0.058
developmental growth GO:0048589 412 0.058
response to external stimulus GO:0009605 289 0.058
Fly
regulation of metabolic process GO:0019222 478 0.058
biosynthetic process GO:0009058 323 0.057
transcription from rna polymerase ii promoter GO:0006366 149 0.057
regulation of primary metabolic process GO:0080090 292 0.057
localization of cell GO:0051674 313 0.057
programmed cell death GO:0012501 500 0.057
cell motility GO:0048870 313 0.056
neuron recognition GO:0008038 83 0.055
signaling GO:0023052 401 0.055
Worm
cell cycle GO:0007049 526 0.055
response to chemical GO:0042221 356 0.055
Fly
apoptotic process GO:0006915 478 0.054
organonitrogen compound metabolic process GO:1901564 151 0.053
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.052
oogenesis GO:0048477 229 0.051
determination of adult lifespan GO:0008340 812 0.051
regulation of gene expression GO:0010468 366 0.050
regulation of post embryonic development GO:0048580 260 0.050
system process GO:0003008 136 0.049
regulation of biosynthetic process GO:0009889 189 0.049
axonogenesis GO:0007409 102 0.049
Fly
positive regulation of cellular metabolic process GO:0031325 178 0.048
negative regulation of macromolecule metabolic process GO:0010605 229 0.048
cellular localization GO:0051641 360 0.047
cell cycle process GO:0022402 482 0.047
cellular component morphogenesis GO:0032989 318 0.047
Fly
establishment of localization in cell GO:0051649 318 0.046
positive regulation of cell communication GO:0010647 69 0.046
multicellular organismal aging GO:0010259 812 0.046
cellular component movement GO:0006928 388 0.045
endocytosis GO:0006897 819 0.045
small molecule metabolic process GO:0044281 186 0.045
positive regulation of transcription dna templated GO:0045893 102 0.045
regulation of developmental growth GO:0048638 389 0.045
macromolecule biosynthetic process GO:0009059 250 0.044
reproductive behavior GO:0019098 387 0.044
muscle tissue development GO:0060537 1 0.044
aging GO:0007568 812 0.044
macromolecule modification GO:0043412 218 0.044
cell projection morphogenesis GO:0048858 148 0.043
Fly
regulation of cellular metabolic process GO:0031323 305 0.043
regulation of localization GO:0032879 194 0.042
multi multicellular organism process GO:0044706 390 0.042
cell migration GO:0016477 306 0.042
positive regulation of gene expression GO:0010628 112 0.042
negative regulation of gene expression GO:0010629 217 0.042
positive regulation of developmental growth GO:0048639 354 0.042
positive regulation of developmental process GO:0051094 408 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.040
cell division GO:0051301 262 0.040
regulation of nematode larval development GO:0061062 260 0.040
cell cell signaling GO:0007267 118 0.040
cellular macromolecule biosynthetic process GO:0034645 247 0.040
cellular component biogenesis GO:0044085 297 0.039
regulation of multicellular organism growth GO:0040014 373 0.039
nucleobase containing compound biosynthetic process GO:0034654 184 0.039
death GO:0016265 547 0.039
multi organism behavior GO:0051705 389 0.039
female gamete generation GO:0007292 254 0.039
Worm
negative regulation of cellular metabolic process GO:0031324 95 0.039
regulation of signaling GO:0023051 172 0.038
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.038
negative regulation of multicellular organismal process GO:0051241 236 0.037
Worm
negative regulation of neurogenesis GO:0050768 4 0.037
positive regulation of growth GO:0045927 369 0.037
positive regulation of nematode larval development GO:0061063 54 0.036
regulation of cell cycle process GO:0010564 145 0.036
regulation of cell differentiation GO:0045595 81 0.036
cellular component assembly GO:0022607 293 0.036
cellular protein modification process GO:0006464 207 0.036
regulation of signal transduction GO:0009966 135 0.035
multicellular organism growth GO:0035264 385 0.035
regulation of macromolecule biosynthetic process GO:0010556 189 0.035
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.035
catabolic process GO:0009056 318 0.034
cell morphogenesis GO:0000902 163 0.034
Fly
positive regulation of vulval development GO:0040026 52 0.034
positive regulation of rna biosynthetic process GO:1902680 102 0.034
phosphate containing compound metabolic process GO:0006796 232 0.033
positive regulation of rna metabolic process GO:0051254 103 0.033
positive regulation of biosynthetic process GO:0009891 109 0.033
rna metabolic process GO:0016070 228 0.033
cell surface receptor signaling pathway GO:0007166 149 0.033
Worm
phosphorus metabolic process GO:0006793 232 0.033
negative regulation of cellular process GO:0048523 239 0.032
positive regulation of multicellular organism growth GO:0040018 352 0.032
cell projection organization GO:0030030 231 0.032
Fly
molting cycle GO:0042303 281 0.032
organic substance catabolic process GO:1901575 294 0.032
positive regulation of signaling GO:0023056 66 0.032
cellular protein metabolic process GO:0044267 279 0.032
cell proliferation GO:0008283 116 0.031
protein localization GO:0008104 205 0.031
regulation of cell fate commitment GO:0010453 22 0.031
cellular response to chemical stimulus GO:0070887 129 0.031
regulation of growth GO:0040008 409 0.031
carbohydrate derivative metabolic process GO:1901135 141 0.031
regulation of nucleic acid templated transcription GO:1903506 165 0.031
tissue development GO:0009888 112 0.031
organelle fission GO:0048285 363 0.030
chemosensory behavior GO:0007635 33 0.030
response to organic substance GO:0010033 131 0.030
cell recognition GO:0008037 85 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.030
oxoacid metabolic process GO:0043436 47 0.030
cellular catabolic process GO:0044248 199 0.030
macromolecular complex subunit organization GO:0043933 320 0.029
secretion GO:0046903 147 0.029
regulation of cellular component organization GO:0051128 248 0.029
positive regulation of neurogenesis GO:0050769 4 0.029
anatomical structure formation involved in morphogenesis GO:0048646 250 0.029
digestive tract development GO:0048565 122 0.029
regulation of cellular biosynthetic process GO:0031326 189 0.029
regulation of locomotion GO:0040012 161 0.029
neuron projection guidance GO:0097485 82 0.028
Fly
chemotaxis GO:0006935 120 0.028
Fly
tube morphogenesis GO:0035239 79 0.027
asymmetric cell division GO:0008356 36 0.027
protein modification process GO:0036211 207 0.027
positive regulation of macromolecule metabolic process GO:0010604 149 0.027
cellular macromolecular complex assembly GO:0034622 184 0.026
organic acid metabolic process GO:0006082 47 0.025
positive regulation of nucleic acid templated transcription GO:1903508 102 0.025
heterocycle catabolic process GO:0046700 119 0.024
dauer larval development GO:0040024 92 0.024
regulation of cell division GO:0051302 142 0.024
regulation of cell proliferation GO:0042127 105 0.024
regulation of cellular component movement GO:0051270 62 0.024
regulation of organelle organization GO:0033043 164 0.023
sensory organ morphogenesis GO:0090596 2 0.023
meiotic nuclear division GO:0007126 300 0.023
neuron projection extension GO:1990138 37 0.023
collagen and cuticulin based cuticle development GO:0040002 99 0.023
regulation of neuron differentiation GO:0045664 40 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.023
Fly
regulation of organ morphogenesis GO:2000027 4 0.023
positive regulation of cellular biosynthetic process GO:0031328 109 0.022
regulation of transport GO:0051049 91 0.022
negative regulation of response to stimulus GO:0048585 73 0.022
organophosphate catabolic process GO:0046434 81 0.022
negative regulation of post embryonic development GO:0048581 208 0.022
phagocytosis GO:0006909 115 0.021
ribonucleotide catabolic process GO:0009261 75 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.021
nervous system development GO:0007399 253 0.021
Fly
regulation of cellular amine metabolic process GO:0033238 0 0.021
single organism cellular localization GO:1902580 72 0.021
epithelial tube morphogenesis GO:0060562 1 0.021
digestive system development GO:0055123 122 0.021
inductive cell migration GO:0040039 145 0.021
positive regulation of post embryonic development GO:0048582 54 0.021
secretion by cell GO:0032940 138 0.021
canonical wnt signaling pathway GO:0060070 3 0.021
response to wounding GO:0009611 4 0.021
carboxylic acid metabolic process GO:0019752 34 0.021
negative regulation of cell communication GO:0010648 61 0.020
intracellular signal transduction GO:0035556 96 0.020
regulation of behavior GO:0050795 97 0.020
negative regulation of developmental process GO:0051093 227 0.020
cell part morphogenesis GO:0032990 152 0.020
Fly
negative regulation of rna metabolic process GO:0051253 53 0.020
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.020
cell type specific apoptotic process GO:0097285 4 0.020
pattern specification process GO:0007389 59 0.020
striated muscle cell differentiation GO:0051146 158 0.019
meiotic cell cycle GO:0051321 335 0.019
cellular ketone metabolic process GO:0042180 14 0.019
protein complex biogenesis GO:0070271 186 0.019
cellular response to organic substance GO:0071310 119 0.019
cellular amino acid metabolic process GO:0006520 15 0.019
positive regulation of signal transduction GO:0009967 40 0.019
digestive tract morphogenesis GO:0048546 76 0.019
tube development GO:0035295 126 0.019
skeletal muscle organ development GO:0060538 3 0.019
organic cyclic compound catabolic process GO:1901361 119 0.019
purine ribonucleotide metabolic process GO:0009150 95 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
protein phosphorylation GO:0006468 85 0.018
axonal fasciculation GO:0007413 79 0.018
macromolecule catabolic process GO:0009057 202 0.018
regulation of gene expression epigenetic GO:0040029 163 0.018
cellular amine metabolic process GO:0044106 15 0.018
membrane organization GO:0061024 135 0.018
muscle structure development GO:0061061 191 0.018
regulation of cell development GO:0060284 49 0.018
organ morphogenesis GO:0009887 67 0.018
cuticle development GO:0042335 100 0.017
chromosome organization GO:0051276 104 0.017
cellular macromolecule localization GO:0070727 75 0.017
nucleoside phosphate metabolic process GO:0006753 108 0.017
single organism behavior GO:0044708 83 0.017
phosphorylation GO:0016310 116 0.017
establishment or maintenance of cell polarity GO:0007163 63 0.017
posttranscriptional regulation of gene expression GO:0010608 166 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.017
synaptic transmission GO:0007268 106 0.017
muscle cell differentiation GO:0042692 171 0.016
striated muscle cell development GO:0055002 157 0.016
aromatic compound catabolic process GO:0019439 116 0.016
rna interference GO:0016246 137 0.016
dendrite development GO:0016358 42 0.016
negative regulation of signal transduction GO:0009968 60 0.016
regeneration GO:0031099 4 0.016
protein complex assembly GO:0006461 186 0.016
organonitrogen compound catabolic process GO:1901565 90 0.016
regulation of response to wounding GO:1903034 1 0.016
gene silencing GO:0016458 143 0.016
positive regulation of neuron differentiation GO:0045666 4 0.016
regionalization GO:0003002 31 0.016
purine containing compound metabolic process GO:0072521 95 0.016
ribonucleoprotein complex assembly GO:0022618 4 0.016
cellular protein complex assembly GO:0043623 178 0.016
myofibril assembly GO:0030239 154 0.015
pharynx development GO:0060465 51 0.015
organelle assembly GO:0070925 214 0.015
nucleobase containing compound catabolic process GO:0034655 114 0.015
embryonic morphogenesis GO:0048598 152 0.015
ribonucleotide metabolic process GO:0009259 99 0.015
apoptotic cell clearance GO:0043277 111 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
cilium organization GO:0044782 32 0.015
regulation of hormone secretion GO:0046883 2 0.015
single organism biosynthetic process GO:0044711 91 0.015
negative regulation of nematode larval development GO:0061064 208 0.015
nucleobase containing small molecule metabolic process GO:0055086 115 0.015
regulation of molecular function GO:0065009 89 0.015
small molecule biosynthetic process GO:0044283 38 0.015
muscle organ morphogenesis GO:0048644 4 0.014
cellular response to stress GO:0033554 162 0.014
regulation of epithelial cell proliferation GO:0050678 1 0.014
regulation of cell fate specification GO:0042659 22 0.014
nucleoside triphosphate metabolic process GO:0009141 87 0.014
gene silencing by rna GO:0031047 143 0.014
negative regulation of neuron differentiation GO:0045665 4 0.014
defense response GO:0006952 296 0.014
Fly
olfactory behavior GO:0042048 27 0.014
organonitrogen compound biosynthetic process GO:1901566 44 0.014
negative regulation of vulval development GO:0040027 206 0.014
purine ribonucleotide catabolic process GO:0009154 75 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
adult behavior GO:0030534 3 0.014
response to temperature stimulus GO:0009266 66 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.014
muscle fiber development GO:0048747 2 0.014
amine metabolic process GO:0009308 15 0.014
regulation of cell motility GO:2000145 57 0.014
developmental cell growth GO:0048588 39 0.014
membrane invagination GO:0010324 98 0.014
myosin filament organization GO:0031033 138 0.014
negative regulation of cellular biosynthetic process GO:0031327 65 0.013
regulation of stem cell differentiation GO:2000736 1 0.013
gabaergic neuron differentiation GO:0097154 1 0.013
purine ribonucleoside catabolic process GO:0046130 75 0.013
positive regulation of response to stimulus GO:0048584 55 0.013
nucleoside catabolic process GO:0009164 78 0.013
purine containing compound catabolic process GO:0072523 75 0.013
gtp catabolic process GO:0006184 46 0.013
phagocytosis engulfment GO:0006911 98 0.013
cell morphogenesis involved in differentiation GO:0000904 112 0.013
Fly
muscle cell development GO:0055001 158 0.013
regulation of intracellular signal transduction GO:1902531 77 0.013
engulfment of apoptotic cell GO:0043652 94 0.013
cellular component assembly involved in morphogenesis GO:0010927 183 0.013
protein complex subunit organization GO:0071822 280 0.013
purine nucleoside triphosphate metabolic process GO:0009144 87 0.013
negative regulation of nucleic acid templated transcription GO:1903507 53 0.013
epithelial cell proliferation GO:0050673 1 0.013
organic substance transport GO:0071702 113 0.013
glycosyl compound catabolic process GO:1901658 79 0.013
pigmentation GO:0043473 2 0.013
cellular nitrogen compound catabolic process GO:0044270 119 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.012
response to other organism GO:0051707 101 0.012
regulation of cell migration GO:0030334 55 0.012
actomyosin structure organization GO:0031032 154 0.012
purine nucleoside catabolic process GO:0006152 75 0.012
cytoskeleton organization GO:0007010 339 0.012
ribonucleoside catabolic process GO:0042454 77 0.012
regulation of nucleocytoplasmic transport GO:0046822 3 0.012
negative regulation of signaling GO:0023057 61 0.012
embryonic body morphogenesis GO:0010172 49 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
purine ribonucleoside metabolic process GO:0046128 92 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
response to biotic stimulus GO:0009607 101 0.012
ribonucleoside triphosphate metabolic process GO:0009199 87 0.012
bmp signaling pathway GO:0030509 3 0.012
axon extension GO:0048675 37 0.012
positive regulation of molecular function GO:0044093 61 0.012
protein catabolic process GO:0030163 162 0.012
locomotory behavior GO:0007626 40 0.012
neuromuscular junction development GO:0007528 2 0.012
ribonucleoside metabolic process GO:0009119 98 0.012
response to external biotic stimulus GO:0043207 101 0.012
posttranscriptional gene silencing GO:0016441 143 0.011
defense response to other organism GO:0098542 100 0.011
organelle localization GO:0051640 127 0.011
male anatomical structure morphogenesis GO:0090598 78 0.011
response to abiotic stimulus GO:0009628 152 0.011
regulation of meiosis GO:0040020 94 0.011
regulation of nuclear division GO:0051783 115 0.011
regulation of filopodium assembly GO:0051489 2 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.011
hormone transport GO:0009914 2 0.011
small gtpase mediated signal transduction GO:0007264 32 0.011
neuron projection morphogenesis GO:0048812 114 0.011
Fly
establishment of organelle localization GO:0051656 123 0.011
ribonucleoside triphosphate catabolic process GO:0009203 72 0.011
regulation of gastrulation GO:0010470 4 0.011
nucleoside phosphate catabolic process GO:1901292 77 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
proximal distal pattern formation GO:0009954 6 0.011
nucleoside triphosphate catabolic process GO:0009143 72 0.011
nucleotide metabolic process GO:0009117 108 0.011
regulation of protein localization GO:0032880 50 0.011
glycosyl compound metabolic process GO:1901657 100 0.011
nematode male tail tip morphogenesis GO:0045138 77 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.011
negative regulation of transcription dna templated GO:0045892 53 0.011
actin filament based process GO:0030029 191 0.011
positive regulation of intracellular transport GO:0032388 2 0.011
regulation of protein metabolic process GO:0051246 81 0.011
regulation of cytoplasmic transport GO:1903649 3 0.011
cell substrate adhesion GO:0031589 1 0.011
tissue morphogenesis GO:0048729 65 0.011
myosin filament assembly GO:0031034 138 0.011
regulation of multi organism process GO:0043900 69 0.011
Worm
regulation of reproductive process GO:2000241 66 0.011
Worm
negative regulation of gene expression epigenetic GO:0045814 2 0.010
positive regulation of protein metabolic process GO:0051247 45 0.010
detection of external stimulus GO:0009581 4 0.010
ribose phosphate metabolic process GO:0019693 99 0.010
regulation of cell cycle GO:0051726 194 0.010
microtubule based process GO:0007017 182 0.010
epithelium development GO:0060429 68 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.010
regulation of canonical wnt signaling pathway GO:0060828 1 0.010
anterior posterior pattern specification GO:0009952 27 0.010

efn-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.011