Caenorhabditis elegans

77 known processes

egl-3 (CELE_C51E3.7)

Protein EGL-3

egl-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization GO:0051234 1171 0.428
establishment of localization in cell GO:0051649 318 0.329
cell cell signaling GO:0007267 118 0.294
signaling GO:0023052 401 0.269
single organism transport GO:0044765 447 0.252
multicellular organismal aging GO:0010259 812 0.212
transport GO:0006810 1093 0.197
single organism localization GO:1902578 518 0.197
embryo development ending in birth or egg hatching GO:0009792 2992 0.190
Worm
cellular localization GO:0051641 360 0.181
multi organism reproductive process GO:0044703 867 0.179
organelle organization GO:0006996 783 0.162
embryo development GO:0009790 3052 0.149
Worm
determination of adult lifespan GO:0008340 812 0.134
secretion by cell GO:0032940 138 0.124
growth GO:0040007 562 0.116
post embryonic development GO:0009791 2152 0.114
Worm Fly
developmental process involved in reproduction GO:0003006 1165 0.110
single organism signaling GO:0044700 401 0.108
behavior GO:0007610 527 0.096
multicellular organismal reproductive process GO:0048609 815 0.093
single organism reproductive process GO:0044702 1196 0.091
hermaphrodite genitalia development GO:0040035 734 0.091
secretion GO:0046903 147 0.083
positive regulation of cellular process GO:0048522 332 0.080
sexual reproduction GO:0019953 546 0.078
multicellular organism reproduction GO:0032504 819 0.077
aging GO:0007568 812 0.076
regulation of biological quality GO:0065008 741 0.075
aromatic compound biosynthetic process GO:0019438 192 0.072
gonad development GO:0008406 840 0.070
nucleic acid metabolic process GO:0090304 299 0.068
organic substance biosynthetic process GO:1901576 323 0.067
body morphogenesis GO:0010171 620 0.061
Worm
cell development GO:0048468 696 0.060
Worm
cytoskeleton organization GO:0007010 339 0.057
lipid storage GO:0019915 565 0.057
development of primary sexual characteristics GO:0045137 840 0.055
protein complex subunit organization GO:0071822 280 0.055
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.055
Worm
maintenance of location GO:0051235 580 0.054
rna metabolic process GO:0016070 228 0.053
multi organism behavior GO:0051705 389 0.053
lipid localization GO:0010876 573 0.050
transcription dna templated GO:0006351 168 0.050
multi organism reproductive behavior GO:0044705 387 0.048
multi multicellular organism process GO:0044706 390 0.048
macromolecular complex subunit organization GO:0043933 320 0.048
oviposition GO:0018991 364 0.045
gamete generation GO:0007276 461 0.045
signal transduction GO:0007165 317 0.045
reproductive structure development GO:0048608 850 0.045
single organism behavior GO:0044708 83 0.044
Fly
molting cycle GO:0042303 281 0.042
Worm
biosynthetic process GO:0009058 323 0.042
nucleobase containing compound biosynthetic process GO:0034654 184 0.042
protein metabolic process GO:0019538 422 0.042
alpha amino acid metabolic process GO:1901605 10 0.040
microtubule based process GO:0007017 182 0.040
peptide metabolic process GO:0006518 7 0.040
single organism organelle organization GO:1902589 501 0.039
vesicle mediated transport GO:0016192 852 0.037
nucleoside phosphate metabolic process GO:0006753 108 0.036
reproductive system development GO:0061458 850 0.036
macromolecule localization GO:0033036 771 0.035
Worm
signal release GO:0023061 28 0.035
regulation of neurotransmitter levels GO:0001505 36 0.034
regulation of biosynthetic process GO:0009889 189 0.033
synaptic vesicle endocytosis GO:0048488 3 0.033
receptor mediated endocytosis GO:0006898 715 0.032
neurotransmitter secretion GO:0007269 26 0.032
cell fate commitment GO:0045165 139 0.032
cell death GO:0008219 547 0.032
regulation of gene expression GO:0010468 366 0.032
positive regulation of macromolecule metabolic process GO:0010604 149 0.032
negative regulation of biological process GO:0048519 567 0.031
response to abiotic stimulus GO:0009628 152 0.031
rna biosynthetic process GO:0032774 169 0.031
multicellular organismal reproductive behavior GO:0033057 384 0.031
ion transport GO:0006811 113 0.031
locomotion GO:0040011 1634 0.031
nucleobase containing compound metabolic process GO:0006139 406 0.031
germ cell development GO:0007281 351 0.031
genitalia development GO:0048806 741 0.030
regulation of cellular metabolic process GO:0031323 305 0.030
small molecule metabolic process GO:0044281 186 0.030
organonitrogen compound metabolic process GO:1901564 151 0.030
gene expression GO:0010467 412 0.029
apical junction assembly GO:0043297 1 0.029
protein modification process GO:0036211 207 0.029
regulation of developmental growth GO:0048638 389 0.029
anatomical structure formation involved in morphogenesis GO:0048646 250 0.029
protein localization GO:0008104 205 0.028
Worm
purine nucleotide metabolic process GO:0006163 95 0.028
multicellular organism growth GO:0035264 385 0.027
carbohydrate derivative metabolic process GO:1901135 141 0.027
response to mechanical stimulus GO:0009612 28 0.027
positive regulation of growth GO:0045927 369 0.027
organic substance catabolic process GO:1901575 294 0.027
positive regulation of multicellular organism growth GO:0040018 352 0.026
cognition GO:0050890 27 0.026
protein catabolic process GO:0030163 162 0.026
cellular protein metabolic process GO:0044267 279 0.026
phosphate containing compound metabolic process GO:0006796 232 0.026
membrane organization GO:0061024 135 0.025
cell cycle GO:0007049 526 0.025
sex differentiation GO:0007548 909 0.025
hormone transport GO:0009914 2 0.025
macromolecule biosynthetic process GO:0009059 250 0.024
cellular component assembly GO:0022607 293 0.024
regulation of primary metabolic process GO:0080090 292 0.024
organ development GO:0048513 1102 0.024
regulation of cellular biosynthetic process GO:0031326 189 0.024
endocytosis GO:0006897 819 0.024
regulation of multicellular organism growth GO:0040014 373 0.024
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.023
chromosome organization GO:0051276 104 0.023
cuticle development GO:0042335 100 0.023
Worm
nervous system development GO:0007399 253 0.023
Mouse Worm
reproductive behavior GO:0019098 387 0.022
cell cycle process GO:0022402 482 0.022
cellular component biogenesis GO:0044085 297 0.022
regulation of growth GO:0040008 409 0.022
peptide hormone processing GO:0016486 2 0.022
regulation of multi organism process GO:0043900 69 0.022
organonitrogen compound catabolic process GO:1901565 90 0.022
protein complex assembly GO:0006461 186 0.021
regulation of localization GO:0032879 194 0.021
learning or memory GO:0007611 27 0.021
cellular biosynthetic process GO:0044249 315 0.021
neuron projection morphogenesis GO:0048812 114 0.021
Worm
regulation of gene expression epigenetic GO:0040029 163 0.021
macromolecule catabolic process GO:0009057 202 0.021
adult behavior GO:0030534 3 0.021
muscle cell differentiation GO:0042692 171 0.021
regulation of multicellular organismal process GO:0051239 726 0.020
regulation of transport GO:0051049 91 0.020
mitotic cell cycle process GO:1903047 194 0.020
muscle structure development GO:0061061 191 0.020
protein complex biogenesis GO:0070271 186 0.019
regulation of cell communication GO:0010646 176 0.019
positive regulation of developmental growth GO:0048639 354 0.019
organic cyclic compound biosynthetic process GO:1901362 195 0.019
catabolic process GO:0009056 318 0.019
olfactory behavior GO:0042048 27 0.019
positive regulation of gene expression GO:0010628 112 0.019
carboxylic acid catabolic process GO:0046395 3 0.019
organic acid metabolic process GO:0006082 47 0.019
regulation of cellular component organization GO:0051128 248 0.018
hormone metabolic process GO:0042445 3 0.018
regulation of rna metabolic process GO:0051252 173 0.018
negative regulation of gene expression GO:0010629 217 0.018
gene silencing GO:0016458 143 0.018
intracellular signal transduction GO:0035556 96 0.018
negative regulation of macromolecule metabolic process GO:0010605 229 0.018
negative regulation of rna biosynthetic process GO:1902679 53 0.018
cation transport GO:0006812 78 0.018
locomotory behavior GO:0007626 40 0.017
organelle fission GO:0048285 363 0.017
cellular nitrogen compound catabolic process GO:0044270 119 0.017
memory GO:0007613 3 0.017
regulation of hormone secretion GO:0046883 2 0.017
heterocycle biosynthetic process GO:0018130 187 0.017
death GO:0016265 547 0.017
cellular nitrogen compound biosynthetic process GO:0044271 192 0.017
protein phosphorylation GO:0006468 85 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.017
intracellular transport GO:0046907 77 0.017
muscle cell development GO:0055001 158 0.017
regulation of organelle organization GO:0033043 164 0.016
regulation of catalytic activity GO:0050790 78 0.016
collagen and cuticulin based cuticle development GO:0040002 99 0.016
Worm
negative regulation of biosynthetic process GO:0009890 65 0.016
response to wounding GO:0009611 4 0.016
striated muscle cell differentiation GO:0051146 158 0.016
detection of external stimulus GO:0009581 4 0.016
oogenesis GO:0048477 229 0.016
inductive cell migration GO:0040039 145 0.015
cellular macromolecular complex assembly GO:0034622 184 0.015
macromolecule modification GO:0043412 218 0.015
nucleoside metabolic process GO:0009116 99 0.015
nucleoside triphosphate metabolic process GO:0009141 87 0.015
cellular protein complex assembly GO:0043623 178 0.015
ribonucleoside monophosphate metabolic process GO:0009161 45 0.015
organelle assembly GO:0070925 214 0.015
nucleic acid templated transcription GO:0097659 169 0.015
regulation of rna biosynthetic process GO:2001141 165 0.015
regulation of nitrogen compound metabolic process GO:0051171 222 0.015
synaptic transmission GO:0007268 106 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
neuron neuron synaptic transmission GO:0007270 22 0.014
negative regulation of response to dna damage stimulus GO:2001021 2 0.014
regulation of macromolecule metabolic process GO:0060255 421 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.014
regulation of metabolic process GO:0019222 478 0.014
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.013
regulation of developmental process GO:0050793 684 0.013
actomyosin structure organization GO:0031032 154 0.013
detection of abiotic stimulus GO:0009582 4 0.013
establishment or maintenance of cell polarity GO:0007163 63 0.013
macromolecular complex assembly GO:0065003 193 0.013
positive regulation of transcription dna templated GO:0045893 102 0.013
peptidyl amino acid modification GO:0018193 58 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 12 0.013
nitrogen compound transport GO:0071705 49 0.013
positive regulation of transferase activity GO:0051347 21 0.013
aromatic compound catabolic process GO:0019439 116 0.013
organelle localization GO:0051640 127 0.013
oxoacid metabolic process GO:0043436 47 0.013
regulation of locomotion GO:0040012 161 0.013
positive regulation of rna biosynthetic process GO:1902680 102 0.012
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.012
heterocycle catabolic process GO:0046700 119 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
negative regulation of gene expression epigenetic GO:0045814 2 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.012
response to chemical GO:0042221 356 0.012
spicule insertion GO:0034609 2 0.012
glycosyl compound metabolic process GO:1901657 100 0.012
regulation of transcription dna templated GO:0006355 164 0.012
organonitrogen compound biosynthetic process GO:1901566 44 0.012
cellular macromolecule biosynthetic process GO:0034645 247 0.012
regulation of cell cycle GO:0051726 194 0.012
myosin filament organization GO:0031033 138 0.012
regulation of signaling GO:0023051 172 0.012
actin filament based process GO:0030029 191 0.012
apoptotic process GO:0006915 478 0.011
organic cyclic compound catabolic process GO:1901361 119 0.011
developmental growth GO:0048589 412 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
regulation of synaptic transmission GO:0050804 34 0.011
establishment of cell polarity GO:0030010 46 0.011
adult locomotory behavior GO:0008344 1 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
protein homooligomerization GO:0051260 3 0.011
negative regulation of metabolic process GO:0009892 240 0.011
system process GO:0003008 136 0.011
Worm
myosin filament assembly GO:0031034 138 0.011
cellular amine metabolic process GO:0044106 15 0.011
insulin metabolic process GO:1901142 2 0.011
negative regulation of cellular process GO:0048523 239 0.011
learning GO:0007612 21 0.011
nucleotide metabolic process GO:0009117 108 0.011
cellular component movement GO:0006928 388 0.011
neurogenesis GO:0022008 236 0.011
Worm
organic substance transport GO:0071702 113 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.011
engulfment of apoptotic cell GO:0043652 94 0.011
regulation of intracellular signal transduction GO:1902531 77 0.011
cell motility GO:0048870 313 0.010
negative regulation of cellular metabolic process GO:0031324 95 0.010
mitotic nuclear division GO:0007067 89 0.010
actin cytoskeleton organization GO:0030036 184 0.010
cellular protein modification process GO:0006464 207 0.010
covalent chromatin modification GO:0016569 30 0.010
rna interference GO:0016246 137 0.010
regulation of cell cycle process GO:0010564 145 0.010
positive regulation of multicellular organismal process GO:0051240 417 0.010

egl-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.034
congenital muscular dystrophy DOID:0050557 0 0.034
muscular disease DOID:0080000 0 0.034
muscular dystrophy DOID:9884 0 0.034
disease of anatomical entity DOID:7 0 0.034
musculoskeletal system disease DOID:17 0 0.034
muscle tissue disease DOID:66 0 0.034
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
organ system cancer DOID:0050686 0 0.015
heart disease DOID:114 0 0.012
cardiomyopathy DOID:0050700 0 0.012
cardiovascular system disease DOID:1287 0 0.012