Caenorhabditis elegans

25 known processes

chk-2 (CELE_Y60A3A.12)

Protein CHK-2

chk-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.175
embryo development GO:0009790 3052 0.166
post embryonic development GO:0009791 2152 0.145
establishment of localization GO:0051234 1171 0.145
single organism reproductive process GO:0044702 1196 0.098
Fly
organ development GO:0048513 1102 0.097
endocytosis GO:0006897 819 0.096
vesicle mediated transport GO:0016192 852 0.095
reproductive structure development GO:0048608 850 0.093
developmental process involved in reproduction GO:0003006 1165 0.091
Fly
organelle organization GO:0006996 783 0.089
transport GO:0006810 1093 0.088
locomotion GO:0040011 1634 0.086
reproductive system development GO:0061458 850 0.085
macromolecule localization GO:0033036 771 0.080
gonad development GO:0008406 840 0.080
sex differentiation GO:0007548 909 0.080
regulation of biological quality GO:0065008 741 0.077
Human
development of primary sexual characteristics GO:0045137 840 0.077
receptor mediated endocytosis GO:0006898 715 0.070
negative regulation of biological process GO:0048519 567 0.067
Human Fly
determination of adult lifespan GO:0008340 812 0.067
cell development GO:0048468 696 0.064
Fly
multicellular organismal aging GO:0010259 812 0.064
aging GO:0007568 812 0.063
maintenance of location GO:0051235 580 0.062
lipid storage GO:0019915 565 0.060
multi organism reproductive process GO:0044703 867 0.058
Fly
lipid localization GO:0010876 573 0.057
genitalia development GO:0048806 741 0.054
regulation of developmental process GO:0050793 684 0.052
hermaphrodite genitalia development GO:0040035 734 0.051
body morphogenesis GO:0010171 620 0.051
localization of cell GO:0051674 313 0.051
growth GO:0040007 562 0.051
regulation of macromolecule metabolic process GO:0060255 421 0.051
Human Fly
regulation of multicellular organismal process GO:0051239 726 0.050
single organism localization GO:1902578 518 0.050
single organism transport GO:0044765 447 0.049
gene expression GO:0010467 412 0.048
Human Fly
signal transduction GO:0007165 317 0.048
Human Mouse Fly
head development GO:0060322 1 0.048
organic substance biosynthetic process GO:1901576 323 0.045
Human Fly
multicellular organismal reproductive process GO:0048609 815 0.045
Fly
cellular component movement GO:0006928 388 0.045
regulation of metabolic process GO:0019222 478 0.044
Human Fly
macromolecular complex subunit organization GO:0043933 320 0.044
Human
behavior GO:0007610 527 0.042
response to chemical GO:0042221 356 0.042
cell cycle GO:0007049 526 0.041
cell motility GO:0048870 313 0.041
single organism signaling GO:0044700 401 0.040
Human Mouse Fly
macromolecule biosynthetic process GO:0009059 250 0.040
Human Fly
protein metabolic process GO:0019538 422 0.040
Human Fly
positive regulation of developmental growth GO:0048639 354 0.040
biosynthetic process GO:0009058 323 0.039
Human Fly
multicellular organism reproduction GO:0032504 819 0.039
Fly
positive regulation of multicellular organismal process GO:0051240 417 0.039
cell migration GO:0016477 306 0.039
developmental growth GO:0048589 412 0.038
cellular localization GO:0051641 360 0.038
cellular protein metabolic process GO:0044267 279 0.038
Human Fly
multi organism behavior GO:0051705 389 0.038
regulation of growth GO:0040008 409 0.037
positive regulation of developmental process GO:0051094 408 0.037
cellular component biogenesis GO:0044085 297 0.037
Human
regulation of multicellular organismal development GO:2000026 317 0.036
vulval development GO:0040025 333 0.036
post embryonic organ development GO:0048569 336 0.036
regulation of vulval development GO:0040028 248 0.036
multi multicellular organism process GO:0044706 390 0.036
regulation of multicellular organism growth GO:0040014 373 0.036
protein complex subunit organization GO:0071822 280 0.035
Human
positive regulation of cellular process GO:0048522 332 0.035
Human Fly
cellular component assembly GO:0022607 293 0.035
Human
signaling GO:0023052 401 0.035
Human Mouse Fly
oviposition GO:0018991 364 0.035
cytoskeleton organization GO:0007010 339 0.035
Human
regulation of primary metabolic process GO:0080090 292 0.034
Human Fly
cell cycle process GO:0022402 482 0.034
multi organism reproductive behavior GO:0044705 387 0.034
nucleic acid metabolic process GO:0090304 299 0.034
Human Fly
neuron development GO:0048666 199 0.033
rna metabolic process GO:0016070 228 0.033
Human Fly
neurogenesis GO:0022008 236 0.033
cellular component morphogenesis GO:0032989 318 0.032
single organism organelle organization GO:1902589 501 0.032
Human
positive regulation of multicellular organism growth GO:0040018 352 0.032
nucleobase containing compound metabolic process GO:0006139 406 0.032
Human Fly
establishment of localization in cell GO:0051649 318 0.031
regulation of response to stimulus GO:0048583 243 0.031
Fly
regulation of cellular biosynthetic process GO:0031326 189 0.031
Human Fly
reproductive behavior GO:0019098 387 0.031
death GO:0016265 547 0.030
Human Mouse Fly
multicellular organismal reproductive behavior GO:0033057 384 0.030
cellular macromolecule biosynthetic process GO:0034645 247 0.030
Human Fly
regulation of developmental growth GO:0048638 389 0.030
regulation of gene expression GO:0010468 366 0.030
Human Fly
programmed cell death GO:0012501 500 0.030
Human Mouse Fly
generation of neurons GO:0048699 235 0.030
regulation of localization GO:0032879 194 0.030
regulation of cellular metabolic process GO:0031323 305 0.029
Human Fly
cellular biosynthetic process GO:0044249 315 0.029
Human Fly
negative regulation of cellular process GO:0048523 239 0.029
Human Fly
cell death GO:0008219 547 0.029
Human Mouse Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.029
regulation of nematode larval development GO:0061062 260 0.029
multicellular organism growth GO:0035264 385 0.029
regulation of nitrogen compound metabolic process GO:0051171 222 0.029
Human Fly
apoptotic process GO:0006915 478 0.028
Human Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.028
Human Fly
meiotic cell cycle GO:0051321 335 0.027
neuron differentiation GO:0030182 217 0.027
negative regulation of developmental process GO:0051093 227 0.027
organonitrogen compound metabolic process GO:1901564 151 0.027
positive regulation of growth GO:0045927 369 0.027
regulation of post embryonic development GO:0048580 260 0.026
protein complex assembly GO:0006461 186 0.026
Human
nervous system development GO:0007399 253 0.026
molting cycle GO:0042303 281 0.025
heterocycle biosynthetic process GO:0018130 187 0.025
Human Fly
catabolic process GO:0009056 318 0.025
Human
negative regulation of multicellular organismal process GO:0051241 236 0.025
cell projection organization GO:0030030 231 0.024
organic substance catabolic process GO:1901575 294 0.024
Human
cell division GO:0051301 262 0.024
negative regulation of gene expression GO:0010629 217 0.024
aromatic compound biosynthetic process GO:0019438 192 0.024
Human Fly
organelle assembly GO:0070925 214 0.024
Human
negative regulation of metabolic process GO:0009892 240 0.024
Human
regulation of macromolecule biosynthetic process GO:0010556 189 0.024
Human Fly
response to wounding GO:0009611 4 0.023
regulation of locomotion GO:0040012 161 0.023
protein modification process GO:0036211 207 0.023
Human Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.023
Human Fly
regulation of cell communication GO:0010646 176 0.023
organic cyclic compound biosynthetic process GO:1901362 195 0.023
Human Fly
sexual reproduction GO:0019953 546 0.023
Fly
sensory organ morphogenesis GO:0090596 2 0.023
regulation of cellular component organization GO:0051128 248 0.023
actin cytoskeleton organization GO:0030036 184 0.023
protein complex biogenesis GO:0070271 186 0.023
Human
actin filament based process GO:0030029 191 0.022
response to external stimulus GO:0009605 289 0.022
regulation of cell cycle GO:0051726 194 0.022
Human Fly
nucleic acid templated transcription GO:0097659 169 0.022
Human Fly
regulation of signaling GO:0023051 172 0.022
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.022
gamete generation GO:0007276 461 0.022
Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.022
Human
defense response GO:0006952 296 0.022
organelle fission GO:0048285 363 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.022
Human Fly
cellular macromolecular complex assembly GO:0034622 184 0.021
macromolecule catabolic process GO:0009057 202 0.021
Human
cellular protein modification process GO:0006464 207 0.021
Human Fly
secretion by cell GO:0032940 138 0.021
microtubule based process GO:0007017 182 0.021
Human
germ cell development GO:0007281 351 0.021
Fly
membrane organization GO:0061024 135 0.021
axon development GO:0061564 163 0.020
rna biosynthetic process GO:0032774 169 0.020
Human Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.020
Human Fly
taxis GO:0042330 128 0.020
cellular protein complex assembly GO:0043623 178 0.020
inductive cell migration GO:0040039 145 0.020
organelle localization GO:0051640 127 0.020
transcription from rna polymerase ii promoter GO:0006366 149 0.020
Fly
small molecule metabolic process GO:0044281 186 0.020
oxoacid metabolic process GO:0043436 47 0.019
regulation of rna biosynthetic process GO:2001141 165 0.019
Human Fly
secretion GO:0046903 147 0.019
transcription dna templated GO:0006351 168 0.019
Human Fly
phosphate containing compound metabolic process GO:0006796 232 0.019
Human Fly
dauer larval development GO:0040024 92 0.019
macromolecular complex assembly GO:0065003 193 0.019
Human
macromolecule modification GO:0043412 218 0.019
Human Fly
regulation of rna metabolic process GO:0051252 173 0.019
Human Fly
negative regulation of post embryonic development GO:0048581 208 0.019
striated muscle cell differentiation GO:0051146 158 0.018
posttranscriptional regulation of gene expression GO:0010608 166 0.018
Human
regeneration GO:0031099 4 0.018
regulation of organelle organization GO:0033043 164 0.018
protein localization GO:0008104 205 0.018
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.018
Fly
cell part morphogenesis GO:0032990 152 0.018
regulation of transcription dna templated GO:0006355 164 0.018
Human Fly
cellular catabolic process GO:0044248 199 0.018
Human
positive regulation of cell projection organization GO:0031346 4 0.018
regulation of nucleic acid templated transcription GO:1903506 165 0.018
Human Fly
regulation of cell migration GO:0030334 55 0.018
skeletal muscle organ development GO:0060538 3 0.018
phosphorus metabolic process GO:0006793 232 0.018
Human Fly
apoptotic cell clearance GO:0043277 111 0.017
neuron projection development GO:0031175 187 0.017
regulation of biosynthetic process GO:0009889 189 0.017
Human Fly
regulation of organ morphogenesis GO:2000027 4 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.017
meiotic nuclear division GO:0007126 300 0.017
muscle cell development GO:0055001 158 0.017
establishment of organelle localization GO:0051656 123 0.017
carboxylic acid metabolic process GO:0019752 34 0.017
epithelial cell proliferation GO:0050673 1 0.016
intracellular signal transduction GO:0035556 96 0.016
Human Mouse Fly
system process GO:0003008 136 0.016
striated muscle cell development GO:0055002 157 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.016
Fly
negative regulation of nematode larval development GO:0061064 208 0.016
cellular component assembly involved in morphogenesis GO:0010927 183 0.016
regulation of cytoplasmic transport GO:1903649 3 0.016
muscle cell differentiation GO:0042692 171 0.016
cell projection morphogenesis GO:0048858 148 0.016
cell recognition GO:0008037 85 0.016
muscle structure development GO:0061061 191 0.016
regulation of nucleocytoplasmic transport GO:0046822 3 0.016
regulation of signal transduction GO:0009966 135 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.016
Fly
immune response GO:0006955 192 0.015
phagocytosis GO:0006909 115 0.015
neuromuscular junction development GO:0007528 2 0.015
cellular response to chemical stimulus GO:0070887 129 0.015
epithelial tube morphogenesis GO:0060562 1 0.015
gene silencing by rna GO:0031047 143 0.015
cell morphogenesis GO:0000902 163 0.015
positive regulation of cellular metabolic process GO:0031325 178 0.015
Human Fly
oogenesis GO:0048477 229 0.015
cellular response to organic substance GO:0071310 119 0.015
positive regulation of neurogenesis GO:0050769 4 0.015
cellular amino acid metabolic process GO:0006520 15 0.015
myofibril assembly GO:0030239 154 0.015
muscle tissue development GO:0060537 1 0.015
amine metabolic process GO:0009308 15 0.015
organic acid metabolic process GO:0006082 47 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
actomyosin structure organization GO:0031032 154 0.015
gene silencing GO:0016458 143 0.015
regulation of gene expression epigenetic GO:0040029 163 0.015
single organism catabolic process GO:0044712 129 0.014
regulation of reproductive process GO:2000241 66 0.014
cell morphogenesis involved in differentiation GO:0000904 112 0.014
negative regulation of vulval development GO:0040027 206 0.014
rna localization GO:0006403 3 0.014
rna interference GO:0016246 137 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
cellular response to abiotic stimulus GO:0071214 4 0.014
Fly
mitotic cell cycle process GO:1903047 194 0.014
Human Fly
phagocytosis engulfment GO:0006911 98 0.014
spindle organization GO:0007051 92 0.014
Human
cell fate commitment GO:0045165 139 0.014
positive regulation of vulval development GO:0040026 52 0.014
engulfment of apoptotic cell GO:0043652 94 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
cellular amine metabolic process GO:0044106 15 0.014
cell proliferation GO:0008283 116 0.014
membrane invagination GO:0010324 98 0.014
regulation of cell cycle process GO:0010564 145 0.014
Human Fly
positive regulation of neuron differentiation GO:0045666 4 0.014
positive regulation of nematode larval development GO:0061063 54 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
positive regulation of metabolic process GO:0009893 187 0.014
Human Fly
posttranscriptional gene silencing by rna GO:0035194 143 0.014
regulation of cell projection assembly GO:0060491 3 0.014
cell type specific apoptotic process GO:0097285 4 0.013
regulation of cell motility GO:2000145 57 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
protein catabolic process GO:0030163 162 0.013
Human
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.013
Human Fly
adult behavior GO:0030534 3 0.013
female gamete generation GO:0007292 254 0.013
axonogenesis GO:0007409 102 0.013
regulation of synapse assembly GO:0051963 2 0.013
response to organic substance GO:0010033 131 0.013
myosin filament assembly GO:0031034 138 0.013
regulation of epithelial cell proliferation GO:0050678 1 0.013
fertilization GO:0009566 63 0.013
ras protein signal transduction GO:0007265 31 0.013
cell surface receptor signaling pathway GO:0007166 149 0.013
negative regulation of gene expression epigenetic GO:0045814 2 0.013
myosin filament organization GO:0031033 138 0.013
cell cell signaling GO:0007267 118 0.013
neuron recognition GO:0008038 83 0.013
regulation of cell proliferation GO:0042127 105 0.013
protein oligomerization GO:0051259 4 0.012
axonal fasciculation GO:0007413 79 0.012
negative regulation of neurogenesis GO:0050768 4 0.012
collagen and cuticulin based cuticle development GO:0040002 99 0.012
positive regulation of post embryonic development GO:0048582 54 0.012
single organism biosynthetic process GO:0044711 91 0.012
Human
positive regulation of cell migration GO:0030335 3 0.012
regulation of cell division GO:0051302 142 0.012
regulation of phosphate metabolic process GO:0019220 81 0.012
meiotic cell cycle process GO:1903046 170 0.012
synaptic transmission GO:0007268 106 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
phosphorylation GO:0016310 116 0.012
Human Fly
regulation of lipid metabolic process GO:0019216 4 0.012
canonical wnt signaling pathway GO:0060070 3 0.012
regulation of cellular component movement GO:0051270 62 0.012
cuticle development GO:0042335 100 0.012
carbohydrate derivative metabolic process GO:1901135 141 0.011
cellular response to stress GO:0033554 162 0.011
Human Zebrafish Mouse Fly
tube development GO:0035295 126 0.011
regulation of meiotic cell cycle GO:0051445 136 0.011
positive regulation of macromolecule metabolic process GO:0010604 149 0.011
Human Fly
ribonucleoprotein complex assembly GO:0022618 4 0.011
embryonic morphogenesis GO:0048598 152 0.011
digestive tract development GO:0048565 122 0.011
innate immune response GO:0045087 190 0.011
chromatin remodeling GO:0006338 2 0.011
response to abiotic stimulus GO:0009628 152 0.011
Mouse Fly
detection of external stimulus GO:0009581 4 0.011
nucleobase containing small molecule metabolic process GO:0055086 115 0.011
regulation of response to wounding GO:1903034 1 0.011
regulation of protein import into nucleus GO:0042306 3 0.011
male sex differentiation GO:0046661 86 0.011
regulation of nuclear division GO:0051783 115 0.011
negative regulation of neuron differentiation GO:0045665 4 0.011
muscle fiber development GO:0048747 2 0.011
response to acid chemical GO:0001101 4 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
Human
regulation of phosphorus metabolic process GO:0051174 81 0.011
ribosome biogenesis GO:0042254 4 0.011
organ morphogenesis GO:0009887 67 0.010
male anatomical structure morphogenesis GO:0090598 78 0.010
regulation of protein targeting GO:1903533 3 0.010
positive regulation of intracellular transport GO:0032388 2 0.010
single fertilization GO:0007338 61 0.010
tissue development GO:0009888 112 0.010
acetylcholine metabolic process GO:0008291 4 0.010
regulation of cell differentiation GO:0045595 81 0.010
single organism intracellular transport GO:1902582 70 0.010
ion transport GO:0006811 113 0.010
adult locomotory behavior GO:0008344 1 0.010
neuron projection morphogenesis GO:0048812 114 0.010
intracellular transport GO:0046907 77 0.010
regulation of behavior GO:0050795 97 0.010
nematode male tail tip morphogenesis GO:0045138 77 0.010

chk-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.011