Caenorhabditis elegans

38 known processes

cyb-2.1 (CELE_Y43E12A.1)

Protein CYB-2.1

cyb-2.1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic chromosome segregation GO:0045132 139 0.594
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.540
single organism reproductive process GO:0044702 1196 0.503
reproductive system development GO:0061458 850 0.492
Worm
embryo development GO:0009790 3052 0.482
gamete generation GO:0007276 461 0.450
genitalia development GO:0048806 741 0.436
Worm
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.431
sexual reproduction GO:0019953 546 0.421
germ cell development GO:0007281 351 0.411
apoptotic process GO:0006915 478 0.403
meiotic cell cycle process GO:1903046 170 0.377
Worm
multicellular organism reproduction GO:0032504 819 0.376
regulation of cell cycle GO:0051726 194 0.371
Human Mouse Worm Fly
female gamete generation GO:0007292 254 0.365
receptor mediated endocytosis GO:0006898 715 0.363
locomotion GO:0040011 1634 0.362
cell cycle GO:0007049 526 0.344
Human Mouse Worm Fly
development of primary sexual characteristics GO:0045137 840 0.336
Worm
meiotic cell cycle GO:0051321 335 0.327
Worm
developmental process involved in reproduction GO:0003006 1165 0.320
cell development GO:0048468 696 0.301
multicellular organismal reproductive process GO:0048609 815 0.299
regulation of mitotic spindle organization GO:0060236 3 0.297
Human
programmed cell death GO:0012501 500 0.288
reproductive structure development GO:0048608 850 0.277
Worm
death GO:0016265 547 0.265
establishment of localization GO:0051234 1171 0.262
Human Worm Fly
organ development GO:0048513 1102 0.254
Mouse Worm
pronuclear migration GO:0035046 51 0.243
Worm
oogenesis GO:0048477 229 0.242
organelle fission GO:0048285 363 0.227
Human Worm Fly
multi organism reproductive process GO:0044703 867 0.219
sex differentiation GO:0007548 909 0.216
Worm
negative regulation of biological process GO:0048519 567 0.214
Human
cell death GO:0008219 547 0.214
chromosome segregation GO:0007059 180 0.203
Human Worm Fly
post embryonic development GO:0009791 2152 0.162
negative regulation of developmental process GO:0051093 227 0.151
signaling GO:0023052 401 0.148
nucleobase containing compound metabolic process GO:0006139 406 0.142
Mouse
regulation of organelle organization GO:0033043 164 0.141
Human Worm
hermaphrodite genitalia development GO:0040035 734 0.140
Worm
gonad development GO:0008406 840 0.133
Worm
mitotic spindle stabilization GO:0043148 2 0.132
Human
macromolecule localization GO:0033036 771 0.126
Human Fly
positive regulation of cellular metabolic process GO:0031325 178 0.118
Worm
transport GO:0006810 1093 0.116
endocytosis GO:0006897 819 0.115
single organism organelle organization GO:1902589 501 0.108
Human Mouse Worm Fly
microtubule polymerization or depolymerization GO:0031109 22 0.100
Human
muscle structure development GO:0061061 191 0.097
meiotic nuclear division GO:0007126 300 0.097
Worm
oocyte development GO:0048599 44 0.092
negative regulation of organelle organization GO:0010639 20 0.092
Human
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.092
cell cycle process GO:0022402 482 0.091
Human Worm Fly
regulation of metabolic process GO:0019222 478 0.090
Worm Fly
regulation of cellular component organization GO:0051128 248 0.086
Human Worm
nervous system development GO:0007399 253 0.084
regulation of microtubule cytoskeleton organization GO:0070507 21 0.083
Human
protein localization GO:0008104 205 0.083
Human Fly
regulation of developmental process GO:0050793 684 0.083
Worm
regulation of biological quality GO:0065008 741 0.082
Human Mouse Fly
response to external stimulus GO:0009605 289 0.082
cytoskeleton dependent cytokinesis GO:0061640 35 0.080
Fly
growth GO:0040007 562 0.078
Mouse Worm
maintenance of location GO:0051235 580 0.076
Human Fly
regulation of chromosome organization GO:0033044 20 0.075
Worm
digestive system development GO:0055123 122 0.073
anatomical structure formation involved in morphogenesis GO:0048646 250 0.073
cell division GO:0051301 262 0.073
Worm Fly
organic substance biosynthetic process GO:1901576 323 0.071
multicellular organismal aging GO:0010259 812 0.069
lipid localization GO:0010876 573 0.067
positive regulation of cellular process GO:0048522 332 0.067
Human Mouse Worm
signal transduction GO:0007165 317 0.065
defense response GO:0006952 296 0.065
aging GO:0007568 812 0.065
negative regulation of cellular component organization GO:0051129 33 0.064
Human
positive regulation of multicellular organismal process GO:0051240 417 0.063
Worm
cellular component morphogenesis GO:0032989 318 0.063
establishment of nucleus localization GO:0040023 55 0.061
Worm
lipid storage GO:0019915 565 0.061
cellular catabolic process GO:0044248 199 0.061
Worm
muscle cell differentiation GO:0042692 171 0.060
regulation of intracellular signal transduction GO:1902531 77 0.059
establishment of localization in cell GO:0051649 318 0.058
Human Worm Fly
regulation of macromolecule metabolic process GO:0060255 421 0.058
Worm Fly
developmental growth GO:0048589 412 0.058
Worm
biosynthetic process GO:0009058 323 0.057
regulation of growth GO:0040008 409 0.056
Worm
cytoskeleton organization GO:0007010 339 0.055
Human Worm Fly
regulation of mitosis GO:0007088 18 0.055
Worm
regulation of response to stimulus GO:0048583 243 0.055
positive regulation of chromosome segregation GO:0051984 1 0.055
Human Worm
regulation of chromosome segregation GO:0051983 20 0.054
Human Worm
establishment of organelle localization GO:0051656 123 0.054
Human Worm Fly
positive regulation of developmental process GO:0051094 408 0.053
Worm
cellular biosynthetic process GO:0044249 315 0.052
organic substance catabolic process GO:1901575 294 0.052
Worm
regulation of signaling GO:0023051 172 0.051
multicellular organism growth GO:0035264 385 0.051
Worm
negative regulation of multicellular organismal process GO:0051241 236 0.050
regulation of transcription dna templated GO:0006355 164 0.049
protein complex subunit organization GO:0071822 280 0.049
Human Worm
regulation of macromolecule biosynthetic process GO:0010556 189 0.049
regulation of cellular biosynthetic process GO:0031326 189 0.048
macromolecular complex subunit organization GO:0043933 320 0.048
Human Mouse Worm
body morphogenesis GO:0010171 620 0.047
catabolic process GO:0009056 318 0.046
Worm
cellular component assembly GO:0022607 293 0.046
single organism signaling GO:0044700 401 0.045
regulation of primary metabolic process GO:0080090 292 0.044
Worm Fly
dna metabolic process GO:0006259 74 0.044
Mouse
regulation of meiotic cell cycle GO:0051445 136 0.044
microtubule depolymerization GO:0007019 10 0.044
Human
protein complex assembly GO:0006461 186 0.044
cytokinesis GO:0000910 80 0.044
Fly
cellular response to stress GO:0033554 162 0.043
Fly
organelle localization GO:0051640 127 0.043
Human Worm Fly
oocyte differentiation GO:0009994 45 0.043
localization of cell GO:0051674 313 0.042
positive regulation of cellular component organization GO:0051130 34 0.042
Human Worm
regulation of cell cycle process GO:0010564 145 0.042
Human Worm
transcription from rna polymerase ii promoter GO:0006366 149 0.041
fertilization GO:0009566 63 0.040
Worm
cellular macromolecule biosynthetic process GO:0034645 247 0.040
regulation of signal transduction GO:0009966 135 0.038
protein catabolic process GO:0030163 162 0.038
Worm
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.037
regulation of cell division GO:0051302 142 0.037
Worm
regulation of developmental growth GO:0048638 389 0.036
Worm
homeostatic process GO:0042592 51 0.036
Mouse
neuron differentiation GO:0030182 217 0.036
cellular protein localization GO:0034613 75 0.036
Human Fly
aromatic compound biosynthetic process GO:0019438 192 0.036
intracellular signal transduction GO:0035556 96 0.035
vulval development GO:0040025 333 0.035
regulation of multicellular organismal process GO:0051239 726 0.035
Worm
nucleobase containing compound biosynthetic process GO:0034654 184 0.035
cellular protein complex disassembly GO:0043624 18 0.035
Human
positive regulation of developmental growth GO:0048639 354 0.035
Worm
nucleus localization GO:0051647 55 0.035
Worm
reproductive behavior GO:0019098 387 0.034
macromolecule biosynthetic process GO:0009059 250 0.034
regulation of nitrogen compound metabolic process GO:0051171 222 0.033
regulation of cell differentiation GO:0045595 81 0.033
regulation of gene expression GO:0010468 366 0.033
nuclear migration GO:0007097 54 0.032
Worm
regulation of cell communication GO:0010646 176 0.032
regulation of nematode larval development GO:0061062 260 0.031
organelle assembly GO:0070925 214 0.031
cellular component movement GO:0006928 388 0.031
Fly
neuron development GO:0048666 199 0.030
positive regulation of chromosome organization GO:2001252 2 0.030
Worm
negative regulation of cellular metabolic process GO:0031324 95 0.030
multi organism reproductive behavior GO:0044705 387 0.030
multi organism behavior GO:0051705 389 0.030
multi multicellular organism process GO:0044706 390 0.030
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.030
Worm
embryonic morphogenesis GO:0048598 152 0.029
digestive tract morphogenesis GO:0048546 76 0.029
negative regulation of cellular process GO:0048523 239 0.028
Human
cellular component assembly involved in morphogenesis GO:0010927 183 0.028
protein complex biogenesis GO:0070271 186 0.028
regulation of cellular metabolic process GO:0031323 305 0.028
Worm Fly
behavior GO:0007610 527 0.028
heterocycle biosynthetic process GO:0018130 187 0.028
striated muscle cell differentiation GO:0051146 158 0.028
phosphorus metabolic process GO:0006793 232 0.027
Mouse Worm Fly
digestive tract development GO:0048565 122 0.027
nucleic acid metabolic process GO:0090304 299 0.027
Mouse
single organism localization GO:1902578 518 0.027
Human Fly
single organism transport GO:0044765 447 0.026
negative regulation of cell cycle GO:0045786 53 0.026
Human
mitotic nuclear division GO:0007067 89 0.026
Human Worm Fly
organic cyclic compound biosynthetic process GO:1901362 195 0.026
vesicle mediated transport GO:0016192 852 0.026
pattern specification process GO:0007389 59 0.026
protein metabolic process GO:0019538 422 0.025
Mouse Worm Fly
protein phosphorylation GO:0006468 85 0.025
Mouse Worm Fly
neuron projection development GO:0031175 187 0.025
tube development GO:0035295 126 0.025
post embryonic organ development GO:0048569 336 0.024
positive regulation of multicellular organism growth GO:0040018 352 0.024
Worm
positive regulation of cellular protein catabolic process GO:1903364 3 0.024
Worm
cellular localization GO:0051641 360 0.024
Human Worm Fly
cell projection organization GO:0030030 231 0.024
cell fate commitment GO:0045165 139 0.024
organelle organization GO:0006996 783 0.023
Human Mouse Worm Fly
dna packaging GO:0006323 7 0.023
Mouse
negative regulation of metabolic process GO:0009892 240 0.023
regulation of microtubule based process GO:0032886 21 0.023
Human
regulation of cell cycle phase transition GO:1901987 13 0.022
Human Worm
cell migration GO:0016477 306 0.022
multicellular organismal reproductive behavior GO:0033057 384 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.022
hatching GO:0035188 48 0.022
cellular nitrogen compound biosynthetic process GO:0044271 192 0.021
mitotic sister chromatid segregation GO:0000070 38 0.021
Human Worm Fly
organism emergence from protective structure GO:0071684 48 0.021
cellular component biogenesis GO:0044085 297 0.021
muscle cell development GO:0055001 158 0.020
negative regulation of mitotic cell cycle GO:0045930 42 0.020
Human
phosphate containing compound metabolic process GO:0006796 232 0.020
Mouse Worm Fly
cellular protein modification process GO:0006464 207 0.020
Mouse Worm Fly
mitotic cell cycle checkpoint GO:0007093 5 0.020
Human
actin filament based process GO:0030029 191 0.020
transcription dna templated GO:0006351 168 0.020
actin cytoskeleton organization GO:0030036 184 0.020
positive regulation of growth GO:0045927 369 0.020
Worm
cell motility GO:0048870 313 0.019
mitotic spindle organization GO:0007052 81 0.019
Human
kinetochore organization GO:0051383 7 0.019
Worm
phosphorylation GO:0016310 116 0.019
Mouse Worm Fly
protein modification process GO:0036211 207 0.019
Mouse Worm Fly
determination of adult lifespan GO:0008340 812 0.019
muscle tissue development GO:0060537 1 0.018
positive regulation of macromolecule metabolic process GO:0010604 149 0.018
Worm
regulation of multicellular organism growth GO:0040014 373 0.018
Worm
immune response GO:0006955 192 0.018
rna biosynthetic process GO:0032774 169 0.018
single fertilization GO:0007338 61 0.018
Worm
myosin filament assembly GO:0031034 138 0.018
negative regulation of post embryonic development GO:0048581 208 0.018
oviposition GO:0018991 364 0.018
cell part morphogenesis GO:0032990 152 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.017
regulation of cytoskeleton organization GO:0051493 41 0.017
Human
regulation of nucleic acid templated transcription GO:1903506 165 0.017
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.017
Worm
mitotic cell cycle process GO:1903047 194 0.017
Human Worm Fly
negative regulation of cellular biosynthetic process GO:0031327 65 0.017
striated muscle cell development GO:0055002 157 0.017
regulation of multicellular organismal development GO:2000026 317 0.017
regulation of rna biosynthetic process GO:2001141 165 0.017
cell projection morphogenesis GO:0048858 148 0.017
cellular protein metabolic process GO:0044267 279 0.017
Mouse Worm Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.017
myosin filament organization GO:0031033 138 0.017
spindle organization GO:0007051 92 0.016
Human
positive regulation of nucleic acid templated transcription GO:1903508 102 0.016
membrane organization GO:0061024 135 0.016
macromolecule catabolic process GO:0009057 202 0.016
Worm
negative regulation of macromolecule metabolic process GO:0010605 229 0.016
microtubule based process GO:0007017 182 0.016
Human Worm Fly
organophosphate metabolic process GO:0019637 125 0.015
gene expression GO:0010467 412 0.015
regulation of post embryonic development GO:0048580 260 0.015
chromatin remodeling GO:0006338 2 0.015
cell cycle phase transition GO:0044770 19 0.015
Human Worm
cellular protein complex assembly GO:0043623 178 0.015
negative regulation of cellular protein metabolic process GO:0032269 27 0.015
head development GO:0060322 1 0.015
striated muscle myosin thick filament assembly GO:0071688 138 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.015
regulation of biosynthetic process GO:0009889 189 0.015
single organism catabolic process GO:0044712 129 0.015
Worm
response to abiotic stimulus GO:0009628 152 0.015
negative regulation of biosynthetic process GO:0009890 65 0.015
response to chemical GO:0042221 356 0.015
positive regulation of phosphorus metabolic process GO:0010562 56 0.014
Worm
cell proliferation GO:0008283 116 0.014
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.014
regulation of vulval development GO:0040028 248 0.014
developmental maturation GO:0021700 26 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
nucleoside triphosphate metabolic process GO:0009141 87 0.014
carbohydrate derivative catabolic process GO:1901136 82 0.014
molting cycle GO:0042303 281 0.014
cellular macromolecule catabolic process GO:0044265 73 0.014
Worm
negative regulation of response to stimulus GO:0048585 73 0.013
regulation of catabolic process GO:0009894 57 0.013
Worm
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
negative regulation of signal transduction GO:0009968 60 0.013
regulation of protein metabolic process GO:0051246 81 0.013
Worm Fly
positive regulation of catabolic process GO:0009896 38 0.013
Worm
adult behavior GO:0030534 3 0.013
regulation of localization GO:0032879 194 0.013
Human
positive regulation of metabolic process GO:0009893 187 0.013
Worm
generation of neurons GO:0048699 235 0.013
myofibril assembly GO:0030239 154 0.013
regulation of mitotic cell cycle GO:0007346 76 0.013
Human Worm
regulation of synapse assembly GO:0051963 2 0.013
regulation of phosphate metabolic process GO:0019220 81 0.013
Worm Fly
macromolecule modification GO:0043412 218 0.013
Mouse Worm Fly
positive regulation of cellular catabolic process GO:0031331 35 0.012
Worm
macromolecular complex assembly GO:0065003 193 0.012
metaphase anaphase transition of cell cycle GO:0044784 15 0.012
Worm
regulation of mitotic sister chromatid segregation GO:0033047 16 0.012
Worm
response to wounding GO:0009611 4 0.012
ribonucleoside triphosphate catabolic process GO:0009203 72 0.012
negative regulation of nematode larval development GO:0061064 208 0.012
peptidyl serine modification GO:0018209 20 0.012
Mouse
signal transduction by phosphorylation GO:0023014 31 0.012
regulation of cellular localization GO:0060341 42 0.012
Human
chromatin assembly GO:0031497 1 0.012
rna metabolic process GO:0016070 228 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
meiosis ii GO:0007135 16 0.011
Worm
cellular response to dna damage stimulus GO:0006974 41 0.011
Fly
purine nucleoside metabolic process GO:0042278 92 0.011
aromatic compound catabolic process GO:0019439 116 0.011
excretion GO:0007588 49 0.011
negative regulation of vulval development GO:0040027 206 0.011
mapk cascade GO:0000165 31 0.011
regulation of lipid metabolic process GO:0019216 4 0.011
cuticle development GO:0042335 100 0.011
spindle checkpoint GO:0031577 4 0.011
Human
neuromuscular junction development GO:0007528 2 0.011
neurogenesis GO:0022008 236 0.011
negative regulation of cell communication GO:0010648 61 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
regeneration GO:0031099 4 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
ribonucleoside triphosphate metabolic process GO:0009199 87 0.010
dendrite development GO:0016358 42 0.010
attachment of spindle microtubules to kinetochore GO:0008608 8 0.010
Human Fly
tissue morphogenesis GO:0048729 65 0.010
protein oligomerization GO:0051259 4 0.010
regulation of cellular protein metabolic process GO:0032268 75 0.010
Worm Fly
ubiquitin dependent protein catabolic process GO:0006511 32 0.010
Worm

cyb-2.1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
thyroid carcinoma DOID:3963 0 0.014
endocrine gland cancer DOID:170 0 0.014
thyroid cancer DOID:1781 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014